Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP123195.RAYvbagGOmcsRa7IneLN14rGOnt6UzQAu3EW_VOgvJHxA130_assertion description "[Racial differences may play an important role concerning the association of variants in the dopamine receptor type 1 gene with essential hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123195.RAYvbagGOmcsRa7IneLN14rGOnt6UzQAu3EW_VOgvJHxA130_provenance.
- NP123197.RAegRqu7Ihjkw_Zx9lIrfDny33F8XDRXQJIWowFtANABo130_assertion description "[4G/4G genotype associated with elevated plasma PAI-1 in Chinese with and without hypertension/of PAI-1 genotype seemed larger in women/hypertensives carrying the 4G/4G genotype, higher TG was correlated with higher PAI-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123197.RAegRqu7Ihjkw_Zx9lIrfDny33F8XDRXQJIWowFtANABo130_provenance.
- NP123204.RAQZuIZQBpXxOyTweYiWgsUaCOjhf1mMCNHyZfkFJC9ng130_assertion description "[Single-nucleotide polymorphims of WNK4 in whites and African Americans with hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123204.RAQZuIZQBpXxOyTweYiWgsUaCOjhf1mMCNHyZfkFJC9ng130_provenance.
- NP123205.RAc6dDOp3Oku9y0oUVuorCuVk5w3_rqOx8aQJvJLxJ5lU130_assertion description "[These data are consistent with the notion that a R44H missense mutation in human RGS2 produces a hypomorphic allele that may lead to altered receptor-mediated G (q) inhibition and contribute to the development of hypertension in affected subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123205.RAc6dDOp3Oku9y0oUVuorCuVk5w3_rqOx8aQJvJLxJ5lU130_provenance.
- NP123209.RAXDLQLK1gTjBYXfPqtRd9zWOWy3kMxrucVE7WIqf2vCc130_assertion description "[REN 10631A alleles are significantly associated with essential hypertension in the Emirati population ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123209.RAXDLQLK1gTjBYXfPqtRd9zWOWy3kMxrucVE7WIqf2vCc130_provenance.
- NP123217.RASlDg8UGd4ils54Y49qjf9KAosLDDVnfUYS-PX87M44U130_assertion description "[ROBO4 mRNA decreases during pulmonary fibrosis and hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123217.RASlDg8UGd4ils54Y49qjf9KAosLDDVnfUYS-PX87M44U130_provenance.
- NP123218.RAQL9-WG98nljhuZVPhXjpqjxrOdVYaMgEL0jweQh8kxE130_assertion description "[These results suggest that polymorphisms -337GA and 565+64CT of XDH gene are related with blood pressure and oxidative stress in hypertension, adding evidence to the role of xanthine oxidoreductase and oxidative stress in blood pressure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123218.RAQL9-WG98nljhuZVPhXjpqjxrOdVYaMgEL0jweQh8kxE130_provenance.
- NP123223.RAd_z13TruCQANSoQvmEu2j-t5o8VFczvMVnuFy4xOtSs130_assertion description "[The current study provides additional evidence that variability at the 11 [beta]HSD1 gene begets the development of hypertension and that over the years changes in the environment have modified the effect of 11 [beta]HSD1 on blood pressure in Pima Indians.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123223.RAd_z13TruCQANSoQvmEu2j-t5o8VFczvMVnuFy4xOtSs130_provenance.
- NP123230.RAWPy2y8wUrOnWVd3xXL3_FKmcR3RlYB_Doc5D4-lgptM130_assertion description "[The present study suggests that none of the major genetic polymorphisms in the RAA system (angiotensinogen, angiotensin-converting enzyme, angiotensin II type 1 receptor, and aldosterone synthase) strongly influence the onset of essential hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123230.RAWPy2y8wUrOnWVd3xXL3_FKmcR3RlYB_Doc5D4-lgptM130_provenance.
- NP123236.RAdc9HnYF0BlpDtAasQCWMvyOeuSblq91tRQphEg49q0E130_assertion description "[90 kDa ACE isoform may be a marker for hypertension which may be related to the development of early atherosclerotic changes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123236.RAdc9HnYF0BlpDtAasQCWMvyOeuSblq91tRQphEg49q0E130_provenance.
- NP123238.RAU9swfZKocUuVjHXIGSHKArfayBdqTU-Z4OIi53ES73M130_assertion description "[ACE2 might play an important role in maintaining a balanced status of local renin-angiotensin system synergistically with ACE by counterregulatory effects confounded by the presence of hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123238.RAU9swfZKocUuVjHXIGSHKArfayBdqTU-Z4OIi53ES73M130_provenance.
- NP123239.RAQihy6-HYSi2UJOseRgtrl9kRBWp04r02b_nbvNuUt5k130_assertion description "[patients with hypertension and congestive heart failure demonstrated the DD angiotensin-converting enzyme genotype and the CC angiotensin II type 1 receptor genotype ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123239.RAQihy6-HYSi2UJOseRgtrl9kRBWp04r02b_nbvNuUt5k130_provenance.
- NP123247.RAYtfCp7gQWlsILmZCx6eoPSwYoytQsYxg_HLVibK-3Go130_assertion description "[The polymorphisms of intron 8 in lipoprotein lipase influence the blood-lipid metabolism, induce blood vessel rebuilding and play an important role in the invasion and development of Essential Hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123247.RAYtfCp7gQWlsILmZCx6eoPSwYoytQsYxg_HLVibK-3Go130_provenance.
- NP123252.RAc0P9J2h5EOqxfLF6Zito72PS6J7mkL1p13d8iWwO0kI130_assertion description "[OPG is increased in pulmonary arterial hypertension and may regulate pulmonary artery smooth muscle cell proliferation and migration ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123252.RAc0P9J2h5EOqxfLF6Zito72PS6J7mkL1p13d8iWwO0kI130_provenance.
- NP123254.RAdOC34-W6KWsQFWJlG-oZDaZrBd2R_FCNi0LOfFJoENc130_assertion description "[Activin A and inhibin A appear to be viable candidates as laboratory parameters for detection of pregnancy induced hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123254.RAdOC34-W6KWsQFWJlG-oZDaZrBd2R_FCNi0LOfFJoENc130_provenance.
- NP123259.RASQyt35x8nelkK-aM0PrwIjuDtnjyNf3ROikQNNK8qM0130_assertion description "[Our data suggest that hypoadiponectinaemia may be involved in the pathogenesis of hypertension in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123259.RASQyt35x8nelkK-aM0PrwIjuDtnjyNf3ROikQNNK8qM0130_provenance.
- NP123263.RAUcWTlQ6xsUzP_QofSkirqfIM6t2B-MFDv5duZMGPj58130_assertion description "[In lungs from patients with idiopathic pulmonary arterial hypertension, NOX4 expression in the tunica media was 2.5-fold upregulated, supporting an important role for NOX4 in the vascular remodeling associated with pulmonary hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123263.RAUcWTlQ6xsUzP_QofSkirqfIM6t2B-MFDv5duZMGPj58130_provenance.
- NP123266.RAeW1bfGcJpoa6BOesy8KqrJZvuHILgp2haMF9gItla6w130_assertion description "[the increase in LVM prevalent in human essential hypertension is directly associated with serum GH levels and inversely related to circulating IGF-1 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123266.RAeW1bfGcJpoa6BOesy8KqrJZvuHILgp2haMF9gItla6w130_provenance.
- NP123276.RAYZ9oa8c4Hl76IJcjvre6D2AIVLsbuujGzgjjklP1y-U130_assertion description "[BMPR2 gene rearrangements have a role in mutations in familial and idiopathic pulmonary arterial hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123276.RAYZ9oa8c4Hl76IJcjvre6D2AIVLsbuujGzgjjklP1y-U130_provenance.
- NP123278.RAWdF3gDatWK4QLRMRorAuCvTKvaG7TfNHzuP6I-LYSKQ130_assertion description "[Stoichiometric imbalance, due to either haplo-insufficiency or loss of optimal receptor-receptor interactions impairs BMPR-II mediated signalling in pulmonary arterial hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123278.RAWdF3gDatWK4QLRMRorAuCvTKvaG7TfNHzuP6I-LYSKQ130_provenance.
- NP123282.RAbkTC-QtKeHcJdIbHGfpZ6zqmFeASBH1XoztCmURZ3eA130_assertion description "[The integration of signals at the level of Id gene expression may contribute to the pathogenesis of familial pulmonary arterial hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123282.RAbkTC-QtKeHcJdIbHGfpZ6zqmFeASBH1XoztCmURZ3eA130_provenance.
- NP123285.RAS8v2MDEUIcDgFoh4mSDDOxqr9FzlhJ3E_e7hNkm84QE130_assertion description "[The Ala92 allele of the type 2 iodothyronine deiodinase increases risk for the development of hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123285.RAS8v2MDEUIcDgFoh4mSDDOxqr9FzlhJ3E_e7hNkm84QE130_provenance.
- NP123289.RAUomv8eTTzwonwZwbKElshtueJxekNaoVEILoA_ylpLQ130_assertion description "[Membrane-bound ATP synthase functions as a receptor for CF6 and may have a previously unsuspected role in the genesis of hypertension by modulating the concentration of intracellular hydrogen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123289.RAUomv8eTTzwonwZwbKElshtueJxekNaoVEILoA_ylpLQ130_provenance.
- NP123295.RAQLWrSuO4sL2DO-2mib35LREvHEZkwTCyD1DX6usLPbE130_assertion description "[High salivary lysozyme levels are associated with the odds of hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123295.RAQLWrSuO4sL2DO-2mib35LREvHEZkwTCyD1DX6usLPbE130_provenance.
- NP123297.RAb5D64tOb1fzkh2vzv-NL9e1-KbqvaU3Pa5zmwhGz8eM130_assertion description "[Significant association between several SNPs and hypertension in US whites, Greek whites, and African-Americans/variation in NEDD4L may play role in development or progression of some forms of hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123297.RAb5D64tOb1fzkh2vzv-NL9e1-KbqvaU3Pa5zmwhGz8eM130_provenance.
- NP123302.RAaBk4gWzDXGJNS24bXXRoz6qrI3hxgCeKPwcNM3ZEKpY130_assertion description "[aldosterone synthase gene polymorphism is not associated with progression of diabetic nephropathy, but it may contribute to the development of hypertension associated with increased aldosterone secretion in type 2 diabetic patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123302.RAaBk4gWzDXGJNS24bXXRoz6qrI3hxgCeKPwcNM3ZEKpY130_provenance.
- NP123308.RAX2dmPnK5BPGRdCwDA3Vzk6cinL7a-vM5ohfYX6jMoyY130_assertion description "[The correlation of the intron-2 conversion allele with high systolic blood pressure and plasma renin ratio associates it with hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123308.RAX2dmPnK5BPGRdCwDA3Vzk6cinL7a-vM5ohfYX6jMoyY130_provenance.
- NP123311.RAeQuvt0r16S-dnRZ1rjMjNqTnZFYLOqMWv1Zr6RPvRWg130_assertion description "[The ACE I/D, alpha-adducin Gly460Trp and aldosterone synthase -344C/T polymorphisms interact to influence systolic blood pressure in Chinese, suggesting that these genes might indeed predispose to hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123311.RAeQuvt0r16S-dnRZ1rjMjNqTnZFYLOqMWv1Zr6RPvRWg130_provenance.
- NP123312.RAVGO5jaY6uPur73dPDCdV7tlbxj-yluNNkTGWNWJD7xs130_assertion description "[Essential hypertension is associated with the TC + TT genotype of rs1126742 in the human CYP4A11 gene ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123312.RAVGO5jaY6uPur73dPDCdV7tlbxj-yluNNkTGWNWJD7xs130_provenance.
- NP123313.RAVZlJApNvrCWsezdXSZQWZ--Q3uOqAftqvY2oSoQymJM130_assertion description "[a functional variant (-845A/G) of CYP4A11 is significantly associated with hypertension and appears to be a novel candidate for a predisposing factor for hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123313.RAVZlJApNvrCWsezdXSZQWZ--Q3uOqAftqvY2oSoQymJM130_provenance.
- NP123314.RAa0zsKh8uXob-gM6lsbGd6qYA5TRaLCgA1w7rVwnjb1A130_assertion description "[Our data strengthen the association between the T8590C polymorphism of CYP4A11 and hypertension and suggest a recessive mode of inheritance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123314.RAa0zsKh8uXob-gM6lsbGd6qYA5TRaLCgA1w7rVwnjb1A130_provenance.
- NP123324.RATTJ5WvK0IPE5qoKFahqjqTcY9GxeDKbC1O-oVtOPvDY130_assertion description "[roles of Thr418Ser polymorphism of the CLCNKB gene and Arg904Gln polymorphism in the TSC gene on essential hypertension need to be explored in other ethnic groups ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123324.RATTJ5WvK0IPE5qoKFahqjqTcY9GxeDKbC1O-oVtOPvDY130_provenance.
- NP123325.RAY3PxyG_nN96OQylKANONDq8hFJaZd33GZtslDUgytBs130_assertion description "[Gitelmans syndrome heterozygotes are partially protected from hypertension through partial genetic loss of function of the NCCT.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123325.RAY3PxyG_nN96OQylKANONDq8hFJaZd33GZtslDUgytBs130_provenance.
- NP123335.RAUnHo3_6iNeqnYwQSP35w9g_jYXrBFKGAz6d8ANzqjLM130_assertion description "[Elevated PAI-1 levels are associated with target organ damage in subjects with newly diagnosed arterial hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123335.RAUnHo3_6iNeqnYwQSP35w9g_jYXrBFKGAz6d8ANzqjLM130_provenance.
- NP123339.RAV8vklKefKf58X8UxZsKL-B0vzf-e9CMJ6c2gQFanK5Y130_assertion description "[Ang II decreases activity of 11beta-HSD2 by AT2 receptor- and MAPK-dependent mechanism/activity of 11beta-HSD2 increases intracellular availability of cortisol/be relevant for pathogenesis of hypertension and preeclampsia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123339.RAV8vklKefKf58X8UxZsKL-B0vzf-e9CMJ6c2gQFanK5Y130_provenance.
- NP123344.RARMUsfxSPaImoodcxcY-pvjYrnHlZvdnp6fH-weXIqrU130_assertion description "[Atp1a1 activity in VSMC and REC cells of rats, dog, and human show that Atp1a1 does not mediate the involvement of ouabain in the development of hypertension in rats, suggesting that the pathogenesis of human and rat hypertension may differ.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123344.RARMUsfxSPaImoodcxcY-pvjYrnHlZvdnp6fH-weXIqrU130_provenance.
- NP123345.RAdOwi9qLOhRdylQn0aTgvcwacE2f1c9LDloXJ-HFs9Mw130_assertion description "[data suggest that Lp (a) and peroxidative stress may be involved as cofactors in essential hypertension, with a mechanism that remains to be elucidated ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123345.RAdOwi9qLOhRdylQn0aTgvcwacE2f1c9LDloXJ-HFs9Mw130_provenance.
- NP123346.RAW3UyndkS0tTz0AMuo3SY-dnXD4Mp8aZltpO9lDwebSQ130_assertion description "[a variant of Secretogranin II has a role in regulation by PHOX2 transcription factors and in hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123346.RAW3UyndkS0tTz0AMuo3SY-dnXD4Mp8aZltpO9lDwebSQ130_provenance.
- NP123354.RAZbZWLnagXL28PiCfBeKiE0YMYWT2Pi7igBcsKgGDbeU130_assertion description "[Identification of a new p22 (phox) polymorphism associated with hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123354.RAZbZWLnagXL28PiCfBeKiE0YMYWT2Pi7igBcsKgGDbeU130_provenance.
- NP123365.RAQcMshvTwZv1kLDcqJqywTI90M2xbyP2TA6wBJPkPrYU130_assertion description "[variants in the FMO3 gene do not predispose to essential hypertension in a cardiovascular disease population of 1649 individuals, 691 (41.9%) of whom had a history of hypertension requiring drug treatment ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123365.RAQcMshvTwZv1kLDcqJqywTI90M2xbyP2TA6wBJPkPrYU130_provenance.
- NP123366.RAbkQtdHytpyfBqe317bjsGIlwsEbhytWan-iijtC8isQ130_assertion description "[Study found that the HLA-DRB1*0406-DQB1*0302 haplotype is associated with idiopathic pulmonary arterial hypertension in Korean patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123366.RAbkQtdHytpyfBqe317bjsGIlwsEbhytWan-iijtC8isQ130_provenance.
- NP123380.RAdcDqV-G-twSaHkkKF6NiozL_2cewb6iS9NlwgXKehv8130_assertion description "[The present study suggests that the SNPs rs482843 and rs1021737 of the CTH gene were not associated with essential hypertension in the Northern Chinese Han population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123380.RAdcDqV-G-twSaHkkKF6NiozL_2cewb6iS9NlwgXKehv8130_provenance.
- NP123384.RAfT_cRLFHSOygHLaMtZQZfWpg012hCHgwOH11nqrLJGo130_assertion description "[A polymorphism in the (alpha) 2B adrenoceptor gene associates with hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123384.RAfT_cRLFHSOygHLaMtZQZfWpg012hCHgwOH11nqrLJGo130_provenance.
- NP123387.RAQhkGbdeMAjr1dxYmDT0gTCUS9cgmhXC-NRJF5IxN0Po130_assertion description "[These results suggest that polymorphisms of ABCA1 and ROS1 are determinants of blood pressure and the development of hypertension in Japanese individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123387.RAQhkGbdeMAjr1dxYmDT0gTCUS9cgmhXC-NRJF5IxN0Po130_provenance.
- NP123397.RARoBJGceLhkzH82gKEluwcRvU06OLbRT53bndZvKNL2o130_assertion description "[Angiotensinogen/renin transgenic rats develop hypertension/in the heart conduction sytsem leads to ventricular tachycardia and sudden arrhythmic death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123397.RARoBJGceLhkzH82gKEluwcRvU06OLbRT53bndZvKNL2o130_provenance.
- NP123406.RAX3wFeXSgKAGK6gImEEWvXv8bWNtRA19o4uteClblXoU130_assertion description "[Common variants of the ENaC gamma subunit confer susceptibility to human essential hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123406.RAX3wFeXSgKAGK6gImEEWvXv8bWNtRA19o4uteClblXoU130_provenance.
- NP123410.RAQSRKbkWWnHOKcwo0WhOI5ADSfyNlqILLkMKzutiFDnY130_assertion description "[Polymorphisms of the angiotensin II receptor, type 2 gene is associated with increased risk of coronary heart disease in hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123410.RAQSRKbkWWnHOKcwo0WhOI5ADSfyNlqILLkMKzutiFDnY130_provenance.
- NP123411.RASCnUs3f5q0xOtGasddCd23eVijtMlUpK5K3UtwQC444130_assertion description "[Hemizygosity for the G allele was found to be susceptibility factor for hypertension in males ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123411.RASCnUs3f5q0xOtGasddCd23eVijtMlUpK5K3UtwQC444130_provenance.
- NP123413.RARh3QImiU1Y4EYFbyVQuUE_EgAvMyEL3V3HF8PR5_nfg130_assertion description "[mitochondrial abnormalities that disturb the reactive O (2) species HIF-1alpha-Kv1.5 O (2) -sensing pathway contribute to the pathogenesis of pulmonary arterial hypertension and cancer--REVIEW ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123413.RARh3QImiU1Y4EYFbyVQuUE_EgAvMyEL3V3HF8PR5_nfg130_provenance.
- NP123414.RAfAoK1-Qb1kzdynFKkCWiwphf0q2HFuo9OSIPISETA6I130_assertion description "[Missense mutation in PTK2B gene is associated with hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123414.RAfAoK1-Qb1kzdynFKkCWiwphf0q2HFuo9OSIPISETA6I130_provenance.
- NP123422.RAZrcUUb2L0VhwLNLszSXBwWFYiL9R4gLtTChi-Va2MvI130_assertion description "[The present findings are compatible with an association of KCNMA1 genetic variations with increased risk of systolic severe hypertension and myocardial infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123422.RAZrcUUb2L0VhwLNLszSXBwWFYiL9R4gLtTChi-Va2MvI130_provenance.
- NP123423.RAU-rRfYaMzixlTMZEckeC4ditYSQTiBL8reRUvSnBjj0130_assertion description "[the frequency of the 6-base insertion in intron 7 of ENG differs between systemic sclerosis patients with or without pulmonary arterial hypertension, suggesting the implication of ENG in this devastating vascular complication of systemic sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123423.RAU-rRfYaMzixlTMZEckeC4ditYSQTiBL8reRUvSnBjj0130_provenance.
- NP123425.RATFTPm9fzQK66TWVmx8v2A42DfykeOr8H9qsSDho6qas130_assertion description "[Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123425.RATFTPm9fzQK66TWVmx8v2A42DfykeOr8H9qsSDho6qas130_provenance.
- NP123435.RAWaMk-RA0UljHnw5-lSYORwJ8BMx4wQTVL0IRi6FQgfo130_assertion description "[These findings argue against important role of coding regions of Sgk1 in blood pressure regulation and hypertension and in the hypertension-related progression of renal diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123435.RAWaMk-RA0UljHnw5-lSYORwJ8BMx4wQTVL0IRi6FQgfo130_provenance.
- NP123443.RASWaIThWhXKa6G7yi_nBx-PdYS_aGNXsjuIJt29uAeXw130_assertion description "[There are polymorphisms in regulatory region of human tissue kallikrein gene in Chinese Han people/in both allele and genotype frequencies show association of hypertension with polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123443.RASWaIThWhXKa6G7yi_nBx-PdYS_aGNXsjuIJt29uAeXw130_provenance.
- NP123447.RAXm0X4ctHnJZJdDiSl2NJ0WXV6fwY964aKi3dciysE-8130_assertion description "[Novel features of this family include a novel DAX1 mutation, marked variability in age of presentation, hypertension on'standard'doses of 9alpha-fludrocortisone and mild testicular enlargement.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123447.RAXm0X4ctHnJZJdDiSl2NJ0WXV6fwY964aKi3dciysE-8130_provenance.
- NP123452.RAQoaHF3QlIP1qj9UgXozgZfzSwqlVghnYoC8Cdyyz8RY130_assertion description "[A novel nonsense polymorphism in the aminopeptidase-a gene was associated with hypertension among postmenopausal women, and those with marginal calcium and vitamin D intake.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123452.RAQoaHF3QlIP1qj9UgXozgZfzSwqlVghnYoC8Cdyyz8RY130_provenance.
- NP123457.RARPdwkVSijE5sQejM9iZLwxwWndC66hGi8k5htFGcuhA130_assertion description "[Catecholamine secretion is influenced by genetic variation in the adrenergic pathway encoding catecholamine synthesis at the rate-limiting step, TH.which may suggest new strategies to approach diagnosis and treatment of hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123457.RARPdwkVSijE5sQejM9iZLwxwWndC66hGi8k5htFGcuhA130_provenance.
- NP123466.RAbq4PUH17KKQU_54EtVRKapqBdRVlKuU4FZxG_xHn0-Y130_assertion description "[Height velocity in the first year of treatment was significantly greater than the pretreatment value/age advanced in the 12 months after commencing treatment/of hGH may be beneficial in treatment of Noonan syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123466.RAbq4PUH17KKQU_54EtVRKapqBdRVlKuU4FZxG_xHn0-Y130_provenance.
- NP123470.RAanQ3HU8r4yr3kVsZjFRXthorRodpk3ga-KLUqQWoNxw130_assertion description "[Mutations in the SOS1 are associated with Noonan syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123470.RAanQ3HU8r4yr3kVsZjFRXthorRodpk3ga-KLUqQWoNxw130_provenance.
- NP123475.RATz9mgX8kQH2G3KLZVzqT9fXCnU-Ht1CYKr5hecqnQfk130_assertion description "[Mutations in the PTPN11 are associated with Noonan syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123475.RATz9mgX8kQH2G3KLZVzqT9fXCnU-Ht1CYKr5hecqnQfk130_provenance.
- NP123478.RAXtcaDbdp1ND9J4fedVla4YUh-MUmBBhfveTP2HM3qFo130_assertion description "[PTPN11 mutations are responsible for Noonan syndrome in Taiwanese patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123478.RAXtcaDbdp1ND9J4fedVla4YUh-MUmBBhfveTP2HM3qFo130_provenance.
- NP123481.RAXcMmrHDY35zGg34lzPB5810ojC4b3FU2Rehvth5Mueo130_assertion description "[SHP-2 mutations in Noonan syndrome cause mild GH resistance by postreceptor signaling defect, partially compensated for by elevated GH secretion/contribute to short stature phenotype in children with SHP-2 mutations and poor response to rhGH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123481.RAXcMmrHDY35zGg34lzPB5810ojC4b3FU2Rehvth5Mueo130_provenance.
- NP123485.RATjaDt8yomsujIFijcvRaTfVpBlcWHlWsO2elPHn_Fsc130_assertion description "[Pathogenesis of Noonan syndrome and leukemia is associated with enhanced phosphatase activity of mutant SHP-2 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123485.RATjaDt8yomsujIFijcvRaTfVpBlcWHlWsO2elPHn_Fsc130_provenance.
- NP123493.RARY9wjdpupT70a7c5QKWEsa5qAb1eiDxK3K82J6WP0Os130_assertion description "[Polymorphisms in the HSD17B5 gene are not associated with risk of polycystic ovary syndrome or elevated testosterone levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123493.RARY9wjdpupT70a7c5QKWEsa5qAb1eiDxK3K82J6WP0Os130_provenance.
- NP123494.RAb-d5sejdb7elXvC-frm2_4EHbH6kUUz87i9zo3ODz5g130_assertion description "[C/T polymorphism in exon 17 of the INSR gene is not associated with susceptibility of polycystic ovary syndrome in a Korean population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123494.RAb-d5sejdb7elXvC-frm2_4EHbH6kUUz87i9zo3ODz5g130_provenance.
- NP123499.RAShw_pmVI4IZ-fO7OsZwo8a6ojp7aDUSa8TolSbkG518130_assertion description "[Relationship of genotypes to phenotypic features of polycystic ovary syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123499.RAShw_pmVI4IZ-fO7OsZwo8a6ojp7aDUSa8TolSbkG518130_provenance.
- NP123501.RAbYbPiM0DJfJklgzN2uPbdZuwOeXi4NaxLQUG6xsVx78130_assertion description "[Negative correlation between serum adiponectin and resistin in polycystic ovary syndrome which might increase of insulin resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123501.RAbYbPiM0DJfJklgzN2uPbdZuwOeXi4NaxLQUG6xsVx78130_provenance.
- NP123503.RAcULlVk5daga5vr_k3lgTHYeUSdgqVBSArTI7VPhdfeg130_assertion description "[Direct inhibitory effect of androgen excess on adiponectin secretion by adipocytes in obese polycystic ovary syndrome patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123503.RAcULlVk5daga5vr_k3lgTHYeUSdgqVBSArTI7VPhdfeg130_provenance.
- NP123505.RAWqtVs0x5KeMjGNQnkXp-4ilRjdvnqc4u7bbrARAqbmE130_assertion description "[Serum adiponectin levels are reduced in obese women with polycystic ovary syndrome/adiponectin does not seem to be actively involved in pathogenesis of PCOS, there seems to be interaction between adiponectin and steroid synthesis or action.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123505.RAWqtVs0x5KeMjGNQnkXp-4ilRjdvnqc4u7bbrARAqbmE130_provenance.
- NP123506.RAX2y9JJ71nhOhP3miAdExLNOG2u2E6IKXexduaPEqOrs130_assertion description "[Both circulating adiponectin levels and the portion present as the most active HMW form are reduced in polycystic ovary syndrome, with differences related to the degree of glucose intolerance and insulin resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123506.RAX2y9JJ71nhOhP3miAdExLNOG2u2E6IKXexduaPEqOrs130_provenance.
- NP123508.RAXi-R8S5orXuOI9L1By9_tsGjo4WSz75y3UAf2Whem5o130_assertion description "[Adipocytokine expression in fat tissue appears to be down-regulated by an increased fat mass; this is particularly evident in the case of adiponectin expression in women with polycystic ovary syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123508.RAXi-R8S5orXuOI9L1By9_tsGjo4WSz75y3UAf2Whem5o130_provenance.
- NP123514.RAUq86Mtg5l4FNr7CCatlebI6tY8wPrualnptxHAOWH0Y130_assertion description "[study suggests that Pro12Ala polymorphism of the proliferator-activated receptor-gamma gene may be a modifier of insulin resistance in women with polycystic ovary syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123514.RAUq86Mtg5l4FNr7CCatlebI6tY8wPrualnptxHAOWH0Y130_provenance.
- NP123515.RAQFX6pw60A4uPv-vA3qei36UGkYGg_Og1Q4-4DEzs5oU130_assertion description "[Higher frequency of C-- > T substitution in exon 6 of PPAR-gamma gene in polycystic ovary syndrome (PCOS)/play role in complex pathogenesis of obesity in PCOS/( 12) Ala polymorphism does not seem to affect body mass index in PCOS women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123515.RAQFX6pw60A4uPv-vA3qei36UGkYGg_Og1Q4-4DEzs5oU130_provenance.
- NP123517.RASBulQ-rFJzWudfF7g8kU2cKYAnRBmmyQMOg16sZllV0130_assertion description "[N-terminal pro-B-type brain natriuretic peptide may have a role in cardiac wall stress in women with polycystic ovary syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123517.RASBulQ-rFJzWudfF7g8kU2cKYAnRBmmyQMOg16sZllV0130_provenance.
- NP123529.RAc9ue0OUn_yi-6KT96Ws_JZFLE1anWlQFZ_33nrtHETY130_assertion description "[Ghrelin levels in women with polycystic ovary syndrome were significantly higher than in obese women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123529.RAc9ue0OUn_yi-6KT96Ws_JZFLE1anWlQFZ_33nrtHETY130_provenance.
- NP123531.RAXBB2MxOu4eqYhcyazUlJp21vnYM8PCU9hKu7VudEYgc130_assertion description "[Polycystic ovary syndrome (PCOS) women have higher ghrelin levels than controls/negatively correlates with BMI and insulin levels in PCOS group/relation between ghrelin and SHBG was observed/could be possible link in PCOS etiology.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123531.RAXBB2MxOu4eqYhcyazUlJp21vnYM8PCU9hKu7VudEYgc130_provenance.
- NP123537.RAVujWAGTwTOVR2_FQrti0N5euuiPMMDQuNEcJXI8k7fs130_assertion description "[lipolytic catecholamine resistance of sc adipocytes in polycystic ovary syndrome is probably due to a combination of decreased amounts of beta (2) -adrenergic receptors, the regulatory II beta-component of protein kinase A, and hormone-sensitive lipase ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123537.RAVujWAGTwTOVR2_FQrti0N5euuiPMMDQuNEcJXI8k7fs130_provenance.
- NP123543.RATFqU0UIQiU9VthAalzSmYnk8ixYZeZxWTCVllNG4Mck130_assertion description "[a relative deficiency of AMH in primordial and transitional follicles in ovaries may contribute to disordered early follicle development in polycystic ovary syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123543.RATFqU0UIQiU9VthAalzSmYnk8ixYZeZxWTCVllNG4Mck130_provenance.
- NP123549.RAbX1GPc2_3IWZEYJ8_L0IylgqlRpYrY0yHxWqxOXOpJk130_assertion description "[lipolytic catecholamine resistance of sc adipocytes in polycystic ovary syndrome is probably due to a combination of decreased amounts of beta (2) -adrenergic receptors, the regulatory II beta-component of protein kinase A, and hormone-sensitive lipase ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123549.RAbX1GPc2_3IWZEYJ8_L0IylgqlRpYrY0yHxWqxOXOpJk130_provenance.
- NP123552.RAQgUkrnKL6chi_-F7i0A7KbTivmwFsyYxvxlyll0qE5E130_assertion description "[dimeric inhibins do not play a central role in the endocrinological imbalance observed in polycystic ovary syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123552.RAQgUkrnKL6chi_-F7i0A7KbTivmwFsyYxvxlyll0qE5E130_provenance.
- NP123553.RAScP8t7bznxMHTo0-6qBcKg3b2WYlLPE40ngZUcIT-2w130_assertion description "[Women with polycystic ovary syndrome have high serum concentration of total inhibin but not of inhibin A or inhibin B.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123553.RAScP8t7bznxMHTo0-6qBcKg3b2WYlLPE40ngZUcIT-2w130_provenance.
- NP123554.RAWy8_Z3r1MEBFXBlplKJXjHitNEvVPAaQuMd_0-LIgM4130_assertion description "[dimeric inhibins do not play a central role in the endocrinological imbalance observed in polycystic ovary syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123554.RAWy8_Z3r1MEBFXBlplKJXjHitNEvVPAaQuMd_0-LIgM4130_provenance.
- NP123559.RAYDXv9ge31-DRoXvyWy9dwJgkGIZaHG7gM81YUQshucI130_assertion description "[The action of growth hormone might be responsible for elevated luteinizing hormone levels and the consequent hyperandrogenic anovulation observed in normal weight women with polycystic ovary syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123559.RAYDXv9ge31-DRoXvyWy9dwJgkGIZaHG7gM81YUQshucI130_provenance.
- NP123561.RAS-ebFDfBScEUOLesedoTdP8UHlmkj_65k2buho8uKhY130_assertion description "[The action of insulin-like growth factor-1 might be responsible for elevated luteinizing hormone levels and the consequent hyperandrogenic anovulation observed in normal weight women with polycystic ovary syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123561.RAS-ebFDfBScEUOLesedoTdP8UHlmkj_65k2buho8uKhY130_provenance.
- NP123564.RAY-P8ecX3rkp5pE-JlHzY_YHi1KWHFIxUeK7rsF847JU130_assertion description "[Elevation in PAI-1 in transgenic mice contributes to the development of polycystic ovary syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123564.RAY-P8ecX3rkp5pE-JlHzY_YHi1KWHFIxUeK7rsF847JU130_provenance.
- NP123566.RAa6_hVxA1weIDn4xOd3KZjI6k_Pb9O5M_aAV9OVBXY0U130_assertion description "[plasminogen activator inhibitor-1 (PAI-1) genotypic subtypes 4G/4G and 4G/5G in polycystic ovary syndrome (PCOS) were present with a statistically higher frequency and PCOS women had higher levels of PAI-1 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123566.RAa6_hVxA1weIDn4xOd3KZjI6k_Pb9O5M_aAV9OVBXY0U130_provenance.
- NP123578.RAXIaMmNMaaG3Pw-0fr2SlzNajU63fchnlLytuMzBB3rQ130_assertion description "[Omentin-1 (ITLN1) is downregulated by insulin and glucose which may explain the decreased omentin-1 levels observed in our overweight women with polycystic ovary syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123578.RAXIaMmNMaaG3Pw-0fr2SlzNajU63fchnlLytuMzBB3rQ130_provenance.
- NP123579.RAQVlsLMuE57wt2cn6qnFvP6DYaK6WplC5k3IBEGPiJBA130_assertion description "[Results suggest that gene polymorphism of IL-6 -174 G > C is a risk factor for polycystic ovary syndrome in Turkish patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123579.RAQVlsLMuE57wt2cn6qnFvP6DYaK6WplC5k3IBEGPiJBA130_provenance.
- NP123583.RAZj2eDhmOc4r9RCNBdc0qT9J0aaOIxeJXjJnARopkh_U130_assertion description "[a common polymorphism of the interleukin-1alpha gene is associated with the presence of polycystic ovary syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123583.RAZj2eDhmOc4r9RCNBdc0qT9J0aaOIxeJXjJnARopkh_U130_provenance.
- NP123585.RATq6Yvg5nT64s_8IuVNn9Cp1284HeNgqRzCXGT_Dyt20130_assertion description "[Obese women with polycystic ovary syndrome have elevated serum concentrations of MMP-9.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123585.RATq6Yvg5nT64s_8IuVNn9Cp1284HeNgqRzCXGT_Dyt20130_provenance.
- NP123586.RAZLAi4uPlUTLMeMnbqm6muE64ByJhcQN3tluHb2C8Kzw130_assertion description "[it is concluded that FST is not a susceptibility locus for polycystic ovary syndrome (PCOS); however, the SNP rs3797297 from FST gene was associated with androgenic markers for PCOS and may be of importance in the hyperandrogenaemia of the disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123586.RAZLAi4uPlUTLMeMnbqm6muE64ByJhcQN3tluHb2C8Kzw130_provenance.
- NP123588.RAcsnKZqRTMjs6e08bzXlEps7JojrTMsELWE1ewi58agM130_assertion description "[In normal endometrium Cyr61 expression is highest in proliferatory phase; it is overexpressed in midsecretory phase in polycystic ovary syndrome (PCOS) and endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123588.RAcsnKZqRTMjs6e08bzXlEps7JojrTMsELWE1ewi58agM130_provenance.
- NP123591.RAX6Yjj-hzGkJFDY5xQo_RXKH5KnLbuG4GvEUMUXgkRgo130_assertion description "[first study to quantify discrete plasminogen activator inhibitor-1 elevations that persist in the setting of polycystic ovary syndrome even with normal or low ambient insulin levels ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123591.RAX6Yjj-hzGkJFDY5xQo_RXKH5KnLbuG4GvEUMUXgkRgo130_provenance.
- NP123594.RAQuxNt7GMCEoUOC7_WhqQXC92UixIYcUD9MjEL8qlk_w130_assertion description "[Changes in 5alpha-reductase, 11beta-HSD1, and 20alpha/beta-HSD enzyme activities observed in polycystic ovary syndrome may contribute to increased production of cortisol and androgens.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123594.RAQuxNt7GMCEoUOC7_WhqQXC92UixIYcUD9MjEL8qlk_w130_provenance.
- NP123604.RAY_bOeyH0aTs7Oy1wnku0cCwSO8mFIBt0RzwMLkjFRMQ130_assertion description "[In codon 462 of exon 7, patients with polycystic ovary syndrome had a 7.4-fold higher frequency of any Val genotype (Ile/Val or Val/Val).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123604.RAY_bOeyH0aTs7Oy1wnku0cCwSO8mFIBt0RzwMLkjFRMQ130_provenance.
- NP123610.RATiDXAVJXNyrBJ5D8wGoHsl-w00lGNIuhVapjX9xCnlo130_assertion description "[In polycystic ovary syndrome (PCOS) theca cells, GATA6 gene transcription and stability of GATA6 mRNA are increased/gene transcription and mRNA stability are likely due to intrinsic differences in PCOS theca cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123610.RATiDXAVJXNyrBJ5D8wGoHsl-w00lGNIuhVapjX9xCnlo130_provenance.
- NP123617.RAQKlLJDNqzXjulEx9MZsSGHK1UBlok4jt61sU-Nshjlg130_assertion description "[diminished NF-1C-dependent repression may be one mechanism underlying increased basal CYP17 promoter activity and altered gene expression in PCOS (polycystic ovary syndrome) theca cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123617.RAQKlLJDNqzXjulEx9MZsSGHK1UBlok4jt61sU-Nshjlg130_provenance.
- NP123618.RAbvWR3qqZowKKyK4vzT_GkF6DKfqSX3WerdpvemBW5yY130_assertion description "[CYP17 promoter is more active in polycystic ovary syndrome theca cells than in normal theca cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123618.RAbvWR3qqZowKKyK4vzT_GkF6DKfqSX3WerdpvemBW5yY130_provenance.
- NP123620.RAbPS_nqMEfkMLK_Wr0TK6Tjy2nrRdSd7pJYK0eStG9_I130_assertion description "[The AR gene CAG repeat polymorphism may contribute to the serum concentration of free testosterone in polycystic ovary syndrome patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123620.RAbPS_nqMEfkMLK_Wr0TK6Tjy2nrRdSd7pJYK0eStG9_I130_provenance.