Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP124037.RAeWHKsv7RdMDZpQ59gXandl-SEnH1Y-vk93AAClT7GnM130_assertion description "[an association between Cdx2 and beta-catenin signaling may participate in induction of transdifferentiation of differentiation in endometrial cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124037.RAeWHKsv7RdMDZpQ59gXandl-SEnH1Y-vk93AAClT7GnM130_provenance.
- NP124045.RAYn1WBRpyHz36-QraKKMcoaahVw82byq9hwyEzIasAb0130_assertion description "[COX-2, MMP-2 and MMP-9 were expressed in a high percentage of primary endometrial carcinomas and their expressions may be associated closely with parameters of tumor aggressiveness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124045.RAYn1WBRpyHz36-QraKKMcoaahVw82byq9hwyEzIasAb0130_provenance.
- NP124049.RAXYnxGTAOyoBmNoM5Jx2FAC54v1lcdURSFae1wuyHSD8130_assertion description "[Cyr61 has a role in suppressing growth of human endometrial cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124049.RAXYnxGTAOyoBmNoM5Jx2FAC54v1lcdURSFae1wuyHSD8130_provenance.
- NP124050.RATWFBqjbGRHcYBFNcrRMZjuVkTFO0PxB0BWtruGPe75Y130_assertion description "[Cyr61 is highly expressed in some endometrial cancer of endometrioid subtype/expression and positive lymph node metastases were independent prognostic factors for patients with endometrioid adenocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124050.RATWFBqjbGRHcYBFNcrRMZjuVkTFO0PxB0BWtruGPe75Y130_provenance.
- NP124051.RAfIfY-WE7RQ839_IuaEBjO7f6y5twaew_XqjuP1d8qqA130_assertion description "[In normal endometrium Cyr61 expression is highest in proliferatory phase; it is overexpressed in midsecretory phase in polycystic ovary syndrome (PCOS) and endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124051.RAfIfY-WE7RQ839_IuaEBjO7f6y5twaew_XqjuP1d8qqA130_provenance.
- NP124055.RAbnzw7LEIfcc-fMHJvsaJ-s1lzpLBj5iTll9xVY-QSEQ130_assertion description "[From a population database of BRCA1 and 2 mutation carriers in Southwestern Ontario, Canada, we identified three women with advanced-stage endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124055.RAbnzw7LEIfcc-fMHJvsaJ-s1lzpLBj5iTll9xVY-QSEQ130_provenance.
- NP124057.RAXMHb96-MFLFzRM3BQ1xKWtTAiFRuS6Q0IRhHCFg7q8w130_assertion description "[The G/G genotype (rs2070959) in the UGT1A1 gene may decrease the risk of endometrial cancer in women with low levels of endogenous estrogen or with low soy intake.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124057.RAXMHb96-MFLFzRM3BQ1xKWtTAiFRuS6Q0IRhHCFg7q8w130_provenance.
- NP124060.RAcFnRcmVBx-KhZ6BU3I8i70E5pdk1ykEQ1JdOGTPIWck130_assertion description "[both SF1 and LRH1 can transcriptionally cooperate with the AP-1 family members c-JUN and c-FOS, known to be associated with enhanced proliferation of endometrial carcinoma cells, to further enhance activation of the STAR, HSD3B2, and CYP19A1 PII promoters ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124060.RAcFnRcmVBx-KhZ6BU3I8i70E5pdk1ykEQ1JdOGTPIWck130_provenance.
- NP124065.RAUQ1KSDDuQfSVbO8R64bayqCeKyOdkfc6C-LCZ1jbxQI130_assertion description "[Increased aromatase expression is associated with endometrioid endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124065.RAUQ1KSDDuQfSVbO8R64bayqCeKyOdkfc6C-LCZ1jbxQI130_provenance.
- NP124067.RASw9yWTDZ9HyJFIk4-kqgN1GF57uNIsTM771IuP3BTco130_assertion description "[cytochrome P450 side chain cleavage mRNA was increased threefold in the ovarian stroma of postmenopausal women with endometrial cancer and endometrial hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124067.RASw9yWTDZ9HyJFIk4-kqgN1GF57uNIsTM771IuP3BTco130_provenance.
- NP124068.RAYkPNZGSXXbUsIRbTTZoCC9Aa6JCgjwm1FzlWtp446bU130_assertion description "[These results suggested that tumor-produced COX-2, which was associated with inhibiting apoptosis and promoting angiogenesis, provided additional prognostic information in endometrial cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124068.RAYkPNZGSXXbUsIRbTTZoCC9Aa6JCgjwm1FzlWtp446bU130_provenance.
- NP124070.RAao2P0h96PbSCjg1IOntVIU6kMK_Rm0tpASS_dKpI-AQ130_assertion description "[These data also suggest that location of intragenic PTEN mutations and their coexistence with the CMYC amplification may play a crucial part in the development of various subtypes of endometrial carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124070.RAao2P0h96PbSCjg1IOntVIU6kMK_Rm0tpASS_dKpI-AQ130_provenance.
- NP124072.RAZ3dldDfuJdngIqw1-zQp-LlkH6ooEeue7QyLufQyDGc130_assertion description "[Mutations in endometrial cancer are the consequence of mismatch repair deficiencies in HNPCC-related cases, but may precede them in sporadic cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124072.RAZ3dldDfuJdngIqw1-zQp-LlkH6ooEeue7QyLufQyDGc130_provenance.
- NP124074.RAQwOz7UhYxoXCSV3iQNPMdZYpeE0P30pfgdFP6DS3EWM130_assertion description "[mTOR signaling pathway is activated in two endometrial carcinoma cell strains and the status of activation is related with PTEN expression of the cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124074.RAQwOz7UhYxoXCSV3iQNPMdZYpeE0P30pfgdFP6DS3EWM130_provenance.
- NP124075.RAZPTJzYATcyG82cfRXdRhqlDKjO-LmM10a-QattQIVBY130_assertion description "[High levels of p-AKT expression occurred independently of the presence of PTEN or PIK3CA mutations in endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124075.RAZPTJzYATcyG82cfRXdRhqlDKjO-LmM10a-QattQIVBY130_provenance.
- NP124079.RAYkmZnmU88nIWd2OWcmrUkyNbOgQjtzaItY-tPhXekIY130_assertion description "[Study demonstrated that PTEN-positive and phosphorylated-Akt-negative expression was a predictor of survival for patients with advanced endometrial carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124079.RAYkmZnmU88nIWd2OWcmrUkyNbOgQjtzaItY-tPhXekIY130_provenance.
- NP124084.RAZ2CJyTaK8oBUNjWS_SqPWfpvJk0iuVmjoaaA053dz8g130_assertion description "[Rare polymorphisms at codons 119 and 432 of CYP1B1 gene have higher risk for endometrial cancer, and positive correlations with ERalpha and ERbeta expressions in endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124084.RAZ2CJyTaK8oBUNjWS_SqPWfpvJk0iuVmjoaaA053dz8g130_provenance.
- NP124089.RAagJN3_bLTKaPUGXDylZmi9-7NNk4HUZE-x7ysYk_yWU130_assertion description "[The SULT1A1*2 allele and long-term use of estrogen replacement therapy were associated with statistically significantly higher risk of endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124089.RAagJN3_bLTKaPUGXDylZmi9-7NNk4HUZE-x7ysYk_yWU130_provenance.
- NP124095.RAf851lnSVWY1CJeH0KdjR2zk4b58zG03clhytxC9Jt0c130_assertion description "[both SF1 and LRH1 can transcriptionally cooperate with the AP-1 family members c-JUN and c-FOS, known to be associated with enhanced proliferation of endometrial carcinoma cells, to further enhance activation of the STAR, HSD3B2, and CYP19A1 PII promoters ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124095.RAf851lnSVWY1CJeH0KdjR2zk4b58zG03clhytxC9Jt0c130_provenance.
- NP124098.RAUt1Aeb-Ljjdg2EJIXVqoSkKE_8edDW_cs8j7XVuAEQI130_assertion description "[The combination of the MDM2 SNP309 and the three TP53 polymorphisms appear to be related to a higher grade of endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124098.RAUt1Aeb-Ljjdg2EJIXVqoSkKE_8edDW_cs8j7XVuAEQI130_provenance.
- NP124101.RASgMoSere9kxdTNgUKZuCGK82qMorQy4UG6abYRBaoug130_assertion description "[The beta-catenin-cyclin D1 pathway might be involved in the growth of endometrial carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124101.RASgMoSere9kxdTNgUKZuCGK82qMorQy4UG6abYRBaoug130_provenance.
- NP124102.RAcdekszFZuyFMXxwVRfw9qp7I-1zo8iblRyHAx_jo8_Q130_assertion description "[These results suggest that soy consumption may interact with polymorphisms in the 17beta-HSD1 gene in relation to endometrial cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124102.RAcdekszFZuyFMXxwVRfw9qp7I-1zo8iblRyHAx_jo8_Q130_provenance.
- NP124103.RAZTij5JqjOHCpgb90ZVIY4pTopbOCv91jgjbji38aJoA130_assertion description "[mTOR signaling pathway is activated in two endometrial carcinoma cell strains and the status of activation is related with PTEN expression of the cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124103.RAZTij5JqjOHCpgb90ZVIY4pTopbOCv91jgjbji38aJoA130_provenance.
- NP124109.RAUYSlkECFRgEF-MhTyyHBnkhm1RApnOlsfvuY-xR2GUY130_assertion description "[The insertion/deletion variant in CYP19A1 (cytochrome P450 family 19 subfamily A polypeptide 1) appears to be related to risk of endometrial cancer; risk associated with variants in this gene may vary according to Body mass idnex ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124109.RAUYSlkECFRgEF-MhTyyHBnkhm1RApnOlsfvuY-xR2GUY130_provenance.
- NP124112.RAfusnGUKhRKdNip94xspRLdhG-4LQtLecqrOL1nQt4IA130_assertion description "[Three CYP19A1 polymorphisms (rs1065779, rs752760, rs1870050) are related to risk of endometrial cancer, effects modified by tea consumption.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124112.RAfusnGUKhRKdNip94xspRLdhG-4LQtLecqrOL1nQt4IA130_provenance.
- NP124113.RAffCLZZSpa3kDwIbqLaMNpN_PTNCEToECpzY-7LGUkko130_assertion description "[Common variants in CYP19A1 (the A alleles of rs749292 and rs727479) influences susceptibility to endometrial cancer, particularly among older and obese women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124113.RAffCLZZSpa3kDwIbqLaMNpN_PTNCEToECpzY-7LGUkko130_provenance.
- NP124115.RAermtcp-mvGdtcWp37G6UtD7NIHI2IbFHeLoMfJoz9Z8130_assertion description "[For CYP17A1 (cytochrome P450 family 17 subfamily A polypeptide 1) risk of endometrial cancer was somewhat lower among women with the C/C genotype at T-34C (rs743572) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124115.RAermtcp-mvGdtcWp37G6UtD7NIHI2IbFHeLoMfJoz9Z8130_provenance.
- NP124117.RAU1XS5uAbDTQSw3BjQ5egVSBm9BIFHd9lcHgR809wOWo130_assertion description "[CYP17 genetic polymorphism is associated with endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124117.RAU1XS5uAbDTQSw3BjQ5egVSBm9BIFHd9lcHgR809wOWo130_provenance.
- NP124119.RAfPR-1x5n8KjEibG3KRFghM2xX8QftstoLi6sIRp4oVw130_assertion description "[we analyzed the signal transduction and COX-2 expression in endometrial cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124119.RAfPR-1x5n8KjEibG3KRFghM2xX8QftstoLi6sIRp4oVw130_provenance.
- NP124124.RARDri0aMrIJ551vmPEkTx-5ZLnIwThE96ggf1MiEoVNQ130_assertion description "[The presence of UG significantly correlated with the expression of estrogen receptor alpha and Progesterone rseceptor in endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124124.RARDri0aMrIJ551vmPEkTx-5ZLnIwThE96ggf1MiEoVNQ130_provenance.
- NP124125.RAXXm1Q8Itj-49xqa3T7mMgKlz0t9qjt-qFzNyACtePVA130_assertion description "[both SF1 and LRH1 can transcriptionally cooperate with the AP-1 family members c-JUN and c-FOS, known to be associated with enhanced proliferation of endometrial carcinoma cells, to further enhance activation of the STAR, HSD3B2, and CYP19A1 PII promoters ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124125.RAXXm1Q8Itj-49xqa3T7mMgKlz0t9qjt-qFzNyACtePVA130_provenance.
- NP124131.RAQWxMWrUEroTIK1BWz13aGKUOZqM4_iPQQtnXiVgah10130_assertion description "[cytochrome P450 17alpha-hydroxylase mRNA was detected in the ovarian stroma of all women with endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124131.RAQWxMWrUEroTIK1BWz13aGKUOZqM4_iPQQtnXiVgah10130_provenance.
- NP124135.RAZDXAYb1Py_XBMP-x-K-U4ZTdsEFUyX4Ja1FmeIgN28I130_assertion description "[CK2 regulates endometrial carcinoma cell sensitivity to TRAIL and Fas by regulating FLIP levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124135.RAZDXAYb1Py_XBMP-x-K-U4ZTdsEFUyX4Ja1FmeIgN28I130_provenance.
- NP124140.RAa0RNvjsB1mOB-VioCk9y7zJGUky5r7w3Lzp6r0PJoQA130_assertion description "[We conclude that the cell adhesion molecule CD44 is expressed infrequently in papillary serous endometrial carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124140.RAa0RNvjsB1mOB-VioCk9y7zJGUky5r7w3Lzp6r0PJoQA130_provenance.
- NP124147.RAQySxsZcgMmEozguALDz3LSJxXN6hPeT0Tyy7ddF4sEs130_assertion description "[KAI-1 and p53 show inverse expression in uterine and endometrial carcinomas and sarcomas/reduced KAI-1 expression may be the result of dysregulated p53 function and could be a step in endometrial carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124147.RAQySxsZcgMmEozguALDz3LSJxXN6hPeT0Tyy7ddF4sEs130_provenance.
- NP124153.RATsFoWwBc1alB4yPWEK1eD_euijQ7fBZ_2YxKdbsjVSQ130_assertion description "[TCF4 expression mediated by beta-catenin/p300 may be important for initial steps during trans-differentiation of endometrial carcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124153.RATsFoWwBc1alB4yPWEK1eD_euijQ7fBZ_2YxKdbsjVSQ130_provenance.
- NP124156.RAfN-E-CKZd7T03CPoOcB4h3rqcgykpYp3auIxXhLixD8130_assertion description "[ESR1 polymorphism maybe associated with risk of endometrial neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124156.RAfN-E-CKZd7T03CPoOcB4h3rqcgykpYp3auIxXhLixD8130_provenance.
- NP124159.RAY13x5fvWfyC1eliy9GCj4SDqve_Bwz1S2Nab0Y2CEAI130_assertion description "[results suggest that the expression of heparanase may influence different malignant behaviors in endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124159.RAY13x5fvWfyC1eliy9GCj4SDqve_Bwz1S2Nab0Y2CEAI130_provenance.
- NP124160.RAahchu4elnXB9NN6lLivJtKOqxdBZNYHQa6S9BWqOBP8130_assertion description "[RASSF1A methylation was observed in a high frequency in endometrioid endometrial carcinoma whereas K-ras and B-raf mutations were observed in a low frequency ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124160.RAahchu4elnXB9NN6lLivJtKOqxdBZNYHQa6S9BWqOBP8130_provenance.
- NP124167.RAWJoIlJJ_RJGo5mz3BcddETOxRyJ10Jk1Ge9jjCpZgWM130_assertion description "[implication of activation of the APC/beta-catenin signalling pathway due to beta-catenin mutations in the development of a subset of endometrial carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124167.RAWJoIlJJ_RJGo5mz3BcddETOxRyJ10Jk1Ge9jjCpZgWM130_provenance.
- NP124172.RAQJUINhvbzYgkH89Ig0CZ2iXgZKgHZOcJovseOLdrjK4130_assertion description "[stimulation of beta-catenin and suppression of gamma-catenin expression, occur within endometrial carcinomas with squamous differentiation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124172.RAQJUINhvbzYgkH89Ig0CZ2iXgZKgHZOcJovseOLdrjK4130_provenance.
- NP124173.RASo-gF2efMi8y2CBRGA9C_2PsucPCPy7AtjVistOiITw130_assertion description "[Findings show that in endometrial hyperplasia and low-grade endometrioid endometrial carcinoma, coordinate increase in cdc25B and phosphorylated ER-alpha occurs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124173.RASo-gF2efMi8y2CBRGA9C_2PsucPCPy7AtjVistOiITw130_provenance.
- NP124174.RAZLJ_hMzACdyHh8KKCpEHzakX9FuThanN_yxbCFZL-rg130_assertion description "[The current results suggested that the codon 327 Asn allele in the SHBG gene may be related to a reduced risk of endometrial cancer among postmenopausal women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124174.RAZLJ_hMzACdyHh8KKCpEHzakX9FuThanN_yxbCFZL-rg130_provenance.
- NP124175.RAfYjwkszaPPIUROXYRpPUS8T3YpJWZVozYNYgMsGkw8Q130_assertion description "[Mutant-type [(12) Asp]K-ras4B can enhance the expression of estrogen receptor alpha and beta proteins and their transcriptional activity as a transcription factor in endometrial carcinoma HEC-1A cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124175.RAfYjwkszaPPIUROXYRpPUS8T3YpJWZVozYNYgMsGkw8Q130_provenance.
- NP124182.RAZEx7MjGO-lmQoR7YuSZNha7yQX5M2nNGeka-iccXOeQ130_assertion description "[loss of Hugl-1 expression in endometrial cancer may contribute to lymph node metastasis and it can be a factor of poor prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124182.RAZEx7MjGO-lmQoR7YuSZNha7yQX5M2nNGeka-iccXOeQ130_provenance.
- NP124186.RAbIQqkoUsr5hjQuZ8FjLeQ1qDtvB5ildX2ox5sxV8mvw130_assertion description "[CK2 regulates endometrial carcinoma cell sensitivity to TRAIL and Fas by regulating FLIP levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124186.RAbIQqkoUsr5hjQuZ8FjLeQ1qDtvB5ildX2ox5sxV8mvw130_provenance.
- NP124189.RAe8zeDdfjfCrrDzbXisQ2s_QcrTq7AglTaCZFOWbcGCc130_assertion description "[Rare polymorphisms at codons 119 and 432 of CYP1B1 gene have higher risk for endometrial cancer, and positive correlations with ERalpha and ERbeta expressions in endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124189.RAe8zeDdfjfCrrDzbXisQ2s_QcrTq7AglTaCZFOWbcGCc130_provenance.
- NP124195.RAbZlAMxw-9bTEYMOM56pTL4tc7_76lgjMFSLZINC9i6c130_assertion description "[Down-regulation of KIAA1324 protein is associated with endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124195.RAbZlAMxw-9bTEYMOM56pTL4tc7_76lgjMFSLZINC9i6c130_provenance.
- NP124203.RAT5Eu-cMwfDKlB3EM-0EQPa9oI2ZQ81j1kxf1EgeyEcs130_assertion description "[Features confirm the pleiotropic effect of ARX gene duplication in X-linked mental retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124203.RAT5Eu-cMwfDKlB3EM-0EQPa9oI2ZQ81j1kxf1EgeyEcs130_provenance.
- NP124206.RASBUJlQGJyDMJOyhx_3r2OBBanRNvBm2LSzD_Avm2VM8130_assertion description "[deletion of the PHF8 gene is associated with the X-linked mental retardation Siderius-Hamel syndrome and the larger size of the Xp11.22 deletion including genes FAM120C and WNK3 may be involved in the pathogenesis of autism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124206.RASBUJlQGJyDMJOyhx_3r2OBBanRNvBm2LSzD_Avm2VM8130_provenance.
- NP124211.RARCXp9ZEr7vXibUaAGBDre0Elc7br-DZND5NYbx_tVFo130_assertion description "[MECP2 gene mutations are correlated with non-syndromic X-linked mental retardation phenotypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124211.RARCXp9ZEr7vXibUaAGBDre0Elc7br-DZND5NYbx_tVFo130_provenance.
- NP124212.RAZyQDH2NDVjsjgvvzYv2cC9Fj4NwtJlfhOIb1qR1jseE130_assertion description "[IL1RAPL1 plays an important role in the etiology of X-linked mental retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124212.RAZyQDH2NDVjsjgvvzYv2cC9Fj4NwtJlfhOIb1qR1jseE130_provenance.
- NP124218.RAbXm5vn4L1J4nRJZLhlmqUVaRLInCFlZFbeJ1L5sI0DQ130_assertion description "[Mutation in CUL4B causes X-linked mental retardation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124218.RAbXm5vn4L1J4nRJZLhlmqUVaRLInCFlZFbeJ1L5sI0DQ130_provenance.
- NP124223.RAcIzZYXRd1EiFBpe4AQKwQk06cHxog2WEBz6S_fCF0Sw130_assertion description "[May play a role in the regulation of translation/cause X-linked mental retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124223.RAcIzZYXRd1EiFBpe4AQKwQk06cHxog2WEBz6S_fCF0Sw130_provenance.
- NP124225.RAQ3sxUHIT9qiUT8Brl_YpO3UO4Zq__eiuximO8JuV63M130_assertion description "[identified a novel FTSJ1 mutation in an X-linked mental retardation family through mutation screening of a cohort of 73 unrelated Japanese male probands with MR ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124225.RAQ3sxUHIT9qiUT8Brl_YpO3UO4Zq__eiuximO8JuV63M130_provenance.
- NP124226.RAaKJmLPqzyf2KHnVg9C5yhQUbECKVhytCc6_dXJDcanw130_assertion description "[Involved in protein ubiquitination in the brain/gene for X-linked mental retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124226.RAaKJmLPqzyf2KHnVg9C5yhQUbECKVhytCc6_dXJDcanw130_provenance.
- NP124230.RAcOcq6QScZPpJtN6fuj2xHifDAguT4eK2nS0G9TEVlpo130_assertion description "[JARID1C may have a role in X-Linked Mental Retardation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124230.RAcOcq6QScZPpJtN6fuj2xHifDAguT4eK2nS0G9TEVlpo130_provenance.
- NP124233.RAaYou8BTncSIcOPjr2Kn50wWF2ZEFsFo_YJD5VEC9KIQ130_assertion description "[SNF2L mutations are not a cause of X-linked mental retardation in our cohort of patients, although we cannot exclude the possibility that regulatory mutations might exist ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124233.RAaYou8BTncSIcOPjr2Kn50wWF2ZEFsFo_YJD5VEC9KIQ130_provenance.
- NP124237.RAV3fN0iYOJXC28MYjEZiL9BP0ofTNXF1W2QG0fuG6Ccs130_assertion description "[Mutations in the polyglutamine-binding protein 1 gene is associated with X-linked mental retardation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124237.RAV3fN0iYOJXC28MYjEZiL9BP0ofTNXF1W2QG0fuG6Ccs130_provenance.
- NP124240.RAd_9THRr23T5aaBUn75KQrfciTYNFMJiN5qLVnx87K0Q130_assertion description "[Increased gene dosage of HSD17B10, HUWE1, or both contribute to the etiology of X-Linked Mental Retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124240.RAd_9THRr23T5aaBUn75KQrfciTYNFMJiN5qLVnx87K0Q130_provenance.
- NP124242.RAUSTPRJXTbJQIQ9WmZI2IBTmo6b7r6L9SYYZCkPcS0L0130_assertion description "[FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124242.RAUSTPRJXTbJQIQ9WmZI2IBTmo6b7r6L9SYYZCkPcS0L0130_provenance.
- NP124244.RAfzrKptlXRuLbQ-sUjq-GGFEJTzuj-na8yMTaKh_vez4130_assertion description "[Single nucleotide polymorphisms, but no disease-associated mutations, were identified in X-linked mental retardation patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124244.RAfzrKptlXRuLbQ-sUjq-GGFEJTzuj-na8yMTaKh_vez4130_provenance.
- NP124252.RARGfIo-i1_2cyi1w5Jj8FwghKwUOQF0g1T0zN_1HHvT8130_assertion description "[are suggestive of the association of ITGA1 with osteoporosis and related risk in postmenopausal women ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124252.RARGfIo-i1_2cyi1w5Jj8FwghKwUOQF0g1T0zN_1HHvT8130_provenance.
- NP124264.RAX4YHyv_aT6r1eGgMM6WWQZKyoOamozzS-b4sOLrLNr8130_assertion description "[The influence of ERalpha polymorphism should be taken into account among the negative factors influencing the development of osteoporosis, especially in the case of prolonged lack or minimal physical activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124264.RAX4YHyv_aT6r1eGgMM6WWQZKyoOamozzS-b4sOLrLNr8130_provenance.
- NP124265.RAY79wBIotR7rogoqkd6CGqmi1sFYQCDROlfcJ2p55XyI130_assertion description "[The specific XbaI and PvuII polymorphisms of the Er gene are associated with low bMD at all bMD measurement sites in the bulgarian female population.they might become useful genetic markers in osteoporosis risk assessment in this specific population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124265.RAY79wBIotR7rogoqkd6CGqmi1sFYQCDROlfcJ2p55XyI130_provenance.
- NP124269.RAdOmHwEFlKS2oQMUhehbpEK8i0RzpG4HjbgGEeueqN2k130_assertion description "[Analysis of the Collal alleles provides early detection of the individuals with hereditary predisposition to osteoporosis and prophylaxis of the disease at the presymptomatic stage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124269.RAdOmHwEFlKS2oQMUhehbpEK8i0RzpG4HjbgGEeueqN2k130_provenance.
- NP124273.RAff3T7arSIBw1gUiXGh6lzOmCQh8F2UvnxXmtmygBTQU130_assertion description "[there were no differences in the -308 TNF-alpha (tumor necrosis factor-alpha) gene promoter polymorphism alleles or geneotype frequencies among patients with or without osteoporosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124273.RAff3T7arSIBw1gUiXGh6lzOmCQh8F2UvnxXmtmygBTQU130_provenance.
- NP124278.RAXoiBCUKV_uNx2zyW3KQpe0WKOKG2_AlCSshUqiHcRlk130_assertion description "[Altered osteoblast proliferation in human osteoporosis may result from dysregulation of IGF-I receptor signaling, including constitutive activation of the IRS-2/Erk signaling pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124278.RAXoiBCUKV_uNx2zyW3KQpe0WKOKG2_AlCSshUqiHcRlk130_provenance.
- NP124281.RASu_B2rmMSoR4OqrwILldsZiHcwRK-g0oDYeda1ZmUks130_assertion description "[Heterozygous carriers of sclerosteosis have bone mineral density consistently higher than mean of healthy subjects without any bone complications encountered in homozygotes/obvious significance for the development of new therapeutics for osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124281.RASu_B2rmMSoR4OqrwILldsZiHcwRK-g0oDYeda1ZmUks130_provenance.
- NP124285.RAV2Eh4yA94ltsUr6FMsYgFv4gXZ8QaH1GoiNkfIN3jNM130_assertion description "[alleles exerting a beneficial effect in young women may subsequently contribute to phenotypes associated with osteoporosis risk in elderly women ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124285.RAV2Eh4yA94ltsUr6FMsYgFv4gXZ8QaH1GoiNkfIN3jNM130_provenance.
- NP124288.RAQe5l8HmHKNKaP1rfBNQ08efwdqXvooJIHQhEPla0kTA130_assertion description "[Variations may be important determinants of osteoporosis in Japanese women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124288.RAQe5l8HmHKNKaP1rfBNQ08efwdqXvooJIHQhEPla0kTA130_provenance.
- NP124290.RAXe8sMC2Z1OSqwYsYNwswe-8apXyG8LMSsHkWaTgPbOo130_assertion description "[The genotype frequencies of VDR were not statistically different between patients with osteoporosis and the control group/VDR haplotypes, bbAATT and bbTtAa are more frequent in the osteoporosis group than the control group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124290.RAXe8sMC2Z1OSqwYsYNwswe-8apXyG8LMSsHkWaTgPbOo130_provenance.
- NP124302.RAdqMTwevnDP7Ln8CLMvgzKn_KYrh0LHCzhxuGQLfmIB0130_assertion description "[Review/RANKL/RANK/OPG system may mediate links between the vascular, skeletal, & immune systems and play a central role in regulating the vascular calcification coincident with declines in skeletal mineralization with age, osteoporosis, or disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124302.RAdqMTwevnDP7Ln8CLMvgzKn_KYrh0LHCzhxuGQLfmIB0130_provenance.
- NP124310.RAbCOYqLD8R1RyQsiU_W7XWuZfzwvKtWzdSrDu7ycc_BI130_assertion description "[RIL and its variant sequences may be an important determinant of osteoporosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124310.RAbCOYqLD8R1RyQsiU_W7XWuZfzwvKtWzdSrDu7ycc_BI130_provenance.
- NP124315.RAeJCxG80YAqMBhClQ1sTnfidUBx3lDarMD-pQVPm4P3k130_assertion description "[both cytochrome P450, family 17 and cytochrome P450, family 19 are candidate genes for osteoporosis in postmenopausal women ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124315.RAeJCxG80YAqMBhClQ1sTnfidUBx3lDarMD-pQVPm4P3k130_provenance.
- NP124317.RAY7kghX6rQaPENo2GnlcoH5omPTsSxJjgqqJLwasQATY130_assertion description "[both cytochrome P450, family 17 and cytochrome P450, family 19 are candidate genes for osteoporosis in postmenopausal women ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124317.RAY7kghX6rQaPENo2GnlcoH5omPTsSxJjgqqJLwasQATY130_provenance.
- NP124327.RAdm3a_OQzAjiLU7cSXc7tloF2zjOvwmoF-LByIS8-wrc130_assertion description "[the C4887A polymorphism of the CYP1A1 gene has an effect on the rate of estrogen catabolism and may represent a possible genetic risk factor for osteoporosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124327.RAdm3a_OQzAjiLU7cSXc7tloF2zjOvwmoF-LByIS8-wrc130_provenance.
- NP124330.RAZmnFntnHBtW6SHELWvkIACSJnXCAICNHqlXZj1kssPA130_assertion description "[REVIEW: role of PYK2 in bone resorption and possible target to prevent osteoporosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124330.RAZmnFntnHBtW6SHELWvkIACSJnXCAICNHqlXZj1kssPA130_provenance.
- NP124333.RAd_3NsGVXMyAAAhrMZRTiOOjVjdmy-_lFr3OsEojfrjI130_assertion description "[A role is demonstrated for the peripherally expressed CB2 receptor in the etiology of osteoporosis, whereas no convincing association is found for cannabinoid receptor type 1 (Cnr1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124333.RAd_3NsGVXMyAAAhrMZRTiOOjVjdmy-_lFr3OsEojfrjI130_provenance.
- NP124334.RAV-FQ4keLapbSWjvt6HtLXgOxOckJ1kSG_JqabTICmm4130_assertion description "[Genetic variations in QPCT are important factors affecting the bone mineral density of adult women that contribute to susceptibility for osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124334.RAV-FQ4keLapbSWjvt6HtLXgOxOckJ1kSG_JqabTICmm4130_provenance.
- NP124341.RAQ64MVcW-XO6BUXAA7TcxLrQ-Lpt7DkNkXwWSgLFpruU130_assertion description "[SHBG may play a key role in male patients with idiopathic or secondary osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124341.RAQ64MVcW-XO6BUXAA7TcxLrQ-Lpt7DkNkXwWSgLFpruU130_provenance.
- NP124345.RAZLUVpYUaKkzQyBy3hra6VGIRwGa42YdAOfeoGRf34qw130_assertion description "[Subjects with the C allele of T-1213C were associated with higher risks of osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124345.RAZLUVpYUaKkzQyBy3hra6VGIRwGa42YdAOfeoGRf34qw130_provenance.
- NP124350.RAbMAcMHAKwKvwT8QUCFuP7QmXMhD59q3vl7uXEpxaSfg130_assertion description "[tumor-specific downregulation of expression and methylation of CDH13 and CDH1, alone or in combination, may be involved in the development and invasive growth of pituitary adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124350.RAbMAcMHAKwKvwT8QUCFuP7QmXMhD59q3vl7uXEpxaSfg130_provenance.
- NP124352.RAYvuA66UF7Y2e74Qx1UYyFMgANy1YKxVUKBkEId7cOHY130_assertion description "[Cox-2 and TBXAS may play an important role in pituitary tumor development and progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124352.RAYvuA66UF7Y2e74Qx1UYyFMgANy1YKxVUKBkEId7cOHY130_provenance.
- NP124354.RAVIe2HLU4Ukp7dxnWEVALq1KXFyjSnyjir9IhQwYaq4k130_assertion description "[Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124354.RAVIe2HLU4Ukp7dxnWEVALq1KXFyjSnyjir9IhQwYaq4k130_provenance.
- NP124361.RAWMh0d8VTMdJMHubvWG4NbISgLi9unFFxpCBTpnowZEI130_assertion description "[strong expression of PPARgamma in human pituitary adenomas and its possible involvement in control of cell proliferation in these tumors ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124361.RAWMh0d8VTMdJMHubvWG4NbISgLi9unFFxpCBTpnowZEI130_provenance.
- NP124364.RAe_fCd-sG0IAZ57G0yZ07P2rJsomN0gK6xzzS4kgp8Ek130_assertion description "[NeuroD1 is differentially expressed in pituitary adenomas and its possible ontogenetic and/or pathogenetic implications in non-corticotroph tumors are discussed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124364.RAe_fCd-sG0IAZ57G0yZ07P2rJsomN0gK6xzzS4kgp8Ek130_provenance.
- NP124372.RAY_56qgUQfFq5k0xuea1pE0oxXfY31Yvp54Fe7KkJyvQ130_assertion description "[PTTG participates in the pathogenesis of various tumors, including pituitary tumors, by inducing aneuploidy and upregulating FGF-2, a potent mitogenic and angiogenic factor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124372.RAY_56qgUQfFq5k0xuea1pE0oxXfY31Yvp54Fe7KkJyvQ130_provenance.
- NP124375.RAUfen_zIoI6Uy-_dm4KODqtKqNkuKcCSodoNb08I2dfU130_assertion description "[Overexpression of B-Raf mRNA and protein may be a feature of nonfunctioning pituitary adenomas, highlighting overactivity of the Ras-B-Raf-MAP kinase pathway in these tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124375.RAUfen_zIoI6Uy-_dm4KODqtKqNkuKcCSodoNb08I2dfU130_provenance.
- NP124376.RAetEEA9UFkLK0weNxoFJSR_3cUYMdCpmxX4rOtvq6viE130_assertion description "[SSTR1 selective activation inhibits hormone secretion and cell viability in GH- and PRL-secreting adenomas in/analogs with affinity for SSTR1 may be useful to control hormone hypersecretion and reduce neoplastic growth of pituitary adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124376.RAetEEA9UFkLK0weNxoFJSR_3cUYMdCpmxX4rOtvq6viE130_provenance.
- NP124381.RAdhX3FH6tnncWxZ8BEXuIJKfu6s1MQ8SCur_jYd_a-wA130_assertion description "[The VEGF-C system may be involved in controlling tumour angiogenesis in the pituitary adenomas lacking lymphatic vessels, but may also play a role in starting the process of tumour lymphangiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124381.RAdhX3FH6tnncWxZ8BEXuIJKfu6s1MQ8SCur_jYd_a-wA130_provenance.
- NP124384.RARxoyLFSVVqiuDkGPH9JHR0luIyjMAgOB-CL4thAIf_M130_assertion description "[findings implicate altered VEGF and KDR signaling in pituitary tumorigenesis; PTTG stimulation of FGF-2 and VEGF expression in the presence of up-regulated growth factor receptors may account for angiogenic growth and progression of human pituitary tumors ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124384.RARxoyLFSVVqiuDkGPH9JHR0luIyjMAgOB-CL4thAIf_M130_provenance.
- NP124388.RAVd2_BhvE4Z5Jvm1UfbzEbuD0AXD-nqg_jAxgsnC6JWg130_assertion description "[Secretagogin might play a role in human non-functional pituitary adenomas/novel finding may provide clues to clarify the basic molecular mechanisms of pituitary adenoma formation, and to identify new tumor-related markers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124388.RAVd2_BhvE4Z5Jvm1UfbzEbuD0AXD-nqg_jAxgsnC6JWg130_provenance.
- NP124391.RAfYOZUP8ejWL2KjN4JkJ_1NJnlt3gVtUcVwczC-sDHpA130_assertion description "[Results strongly suggest that DDR1 mediates cell invasion-related signaling between collagen type I and MMP-2 and -9 in pituitary adenoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124391.RAfYOZUP8ejWL2KjN4JkJ_1NJnlt3gVtUcVwczC-sDHpA130_provenance.
- NP124392.RAXzltWFysAO148oGsXgEhG4Deo4C8tBxbxTEVhV1cVmY130_assertion description "[increases invasion in human pituitary adenoma cell line ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124392.RAXzltWFysAO148oGsXgEhG4Deo4C8tBxbxTEVhV1cVmY130_provenance.
- NP124395.RAfd3nbHR2KuiNWXKQmdblyj7SfUA21eE-8g3vgRljgwU130_assertion description "[Results provide novel evidence for a permissive role of retinoids on the expression of dopamine D2 receptors in a good proportion of pituitary tumors and on the generation of pro-apoptotic signals in GH3 cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124395.RAfd3nbHR2KuiNWXKQmdblyj7SfUA21eE-8g3vgRljgwU130_provenance.
- NP124396.RASW4ZTl5I3mdq1dLhsgr4vgejRKAX3pTyJDFrffKLNks130_assertion description "[Functional D (2) receptors were expressed in approximately 80% of corticotroph pituitary tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124396.RASW4ZTl5I3mdq1dLhsgr4vgejRKAX3pTyJDFrffKLNks130_provenance.
- NP124397.RAcf01T_caMK3xwMqE6dTM72XNF52TjUQrdMokMSxRhJ8130_assertion description "[Results suggest that the expression pattern of dopamine receptor 2 and somatostatin receptor 5 may influence the effects of SRIF analogs in growth hormone-secreting pituitary adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124397.RAcf01T_caMK3xwMqE6dTM72XNF52TjUQrdMokMSxRhJ8130_provenance.
- NP124404.RAfgYjptxLxH-l-sEWLSu5gJ-S6rTgUDOs2gHP--z0lyQ130_assertion description "[an increased CCNB2 expression in human pituitary adenomas of different histotypes that is directly correlated with HMGA1 and HMGA2 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124404.RAfgYjptxLxH-l-sEWLSu5gJ-S6rTgUDOs2gHP--z0lyQ130_provenance.
- NP124406.RAX9KKKV94OY9udH6UcCwiW4nSPI2x9x_siHv8_odfnXI130_assertion description "[The relationship between pituitary tumour transforming gene (PTTG) expression and in vitro growth hormone and vascular endothelial growth factor (VEGF) secretion from human pituitary adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124406.RAX9KKKV94OY9udH6UcCwiW4nSPI2x9x_siHv8_odfnXI130_provenance.