Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP125159.RAQX3gsk5CqoW5xBmZkj4h6hfABBrt4t-xWIJP3yiOHGE130_assertion description "[Acute myelocytic leukemia cells expresse INDO mRNA, but not IDO protein when exposed to optimal concentrations of IFN-gamma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125159.RAQX3gsk5CqoW5xBmZkj4h6hfABBrt4t-xWIJP3yiOHGE130_provenance.
- NP125160.RARlbKOqvc6GWyiQKv4Rn6LdGXr-ISnG4S2Wq4isprf6Q130_assertion description "[determined INDO mRNA expression in leukemic blasts of 286 patients with acute myeloid leukemia by gene-expression profiling; high INDO expression is a strong negative independent predicting variable for overall and relapse-free survival ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125160.RARlbKOqvc6GWyiQKv4Rn6LdGXr-ISnG4S2Wq4isprf6Q130_provenance.
- NP125163.RAWz1czA-DXviZEgTVVU_8FNiFySMcZ4ObGNvYiwSHdps130_assertion description "[Translocations in acute myeloid leukemia (AML) is the t (8; 21) is characterized by AML1-MTG8 (ETO) mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125163.RAWz1czA-DXviZEgTVVU_8FNiFySMcZ4ObGNvYiwSHdps130_provenance.
- NP125166.RAeUpt7D_722aGlLhJYRTlQ1inMzflSwO2VPZ4lJGGVFY130_assertion description "[The t (8; 21) fusion protein, AML1 ETO, specifically represses the transcription of the p14 (ARF) tumor suppressor in acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125166.RAeUpt7D_722aGlLhJYRTlQ1inMzflSwO2VPZ4lJGGVFY130_provenance.
- NP125169.RAf7Fr43OCuFrw-DPTf8mmVh7f-udAcUHtaRYaTbj99tg130_assertion description "[plasma levels of adiponectin and TNFalpha are upregulated in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125169.RAf7Fr43OCuFrw-DPTf8mmVh7f-udAcUHtaRYaTbj99tg130_provenance.
- NP125181.RAecwAWmAJ4gJxOpf_bjsdM0heBJ495IvIYSJQf6K-_p4130_assertion description "[In the Acute Myeloid Leukemia patients, detected MLL rearrangements consisting of MLL/AF6, MLL/AF9, MLL/AF17, MLL/ELL and MLL partial tandem duplication/rearrangement include chromosome translocation and partial tandem duplication.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125181.RAecwAWmAJ4gJxOpf_bjsdM0heBJ495IvIYSJQf6K-_p4130_provenance.
- NP125186.RAQrZ02Gvkf0pVtF9Sz5_fkd0QGis8cHQwlrJlj97CTAk130_assertion description "[Translocation 11q23 and MLL gene rearrangements observed in acute myeloid leukemia in a 15-yeaar-old girl.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125186.RAQrZ02Gvkf0pVtF9Sz5_fkd0QGis8cHQwlrJlj97CTAk130_provenance.
- NP125188.RAf9t5lA2ia1qgtnTbyoc05Fp7mPaGmY3Mx-XJarGZnnE130_assertion description "[In acute myeloid leukemia with mixed lineage leukemia partial tandem duplication, the SLC5A8 tumor suppressor gene promoter was more frequently hypermethylated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125188.RAf9t5lA2ia1qgtnTbyoc05Fp7mPaGmY3Mx-XJarGZnnE130_provenance.
- NP125191.RAWFBMtXbnqtRYtNQlN7e-_g4pM81EzXhRJuewplqh_wM130_assertion description "[SEPTIN6, a human homologue to mouse Septin6, is fused to MLL in infant acute myeloid leukemia with complex chromosomal abnormalities involving 11q23 and Xq24.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125191.RAWFBMtXbnqtRYtNQlN7e-_g4pM81EzXhRJuewplqh_wM130_provenance.
- NP125193.RAYJxezUuXHxFV2nf0HOslBhKtF7GStQSfAj34SWqDT_M130_assertion description "[demonstrated that TET1 is fused to MLL in a case of pediatric acute myeloid leukemia containing the t (10; 11) (q22; q23) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125193.RAYJxezUuXHxFV2nf0HOslBhKtF7GStQSfAj34SWqDT_M130_provenance.
- NP125194.RAcmPiWELfo3rZDM0ORx7RGb2r3WzwZNWXAUuGBZWHwAk130_assertion description "[extensive methylation of hmlh1 is associated with the presence of a defective DNA mismatch repair pathway resulting in microsatellite instability in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125194.RAcmPiWELfo3rZDM0ORx7RGb2r3WzwZNWXAUuGBZWHwAk130_provenance.
- NP125195.RAbZx99vP0YCDRRFAZYoZnKQOkvAykea4GzSis1CtkoHs130_assertion description "[Aberrant promoter methylation of DNA mismatch repair enzyme MLH1 is detectable in a small number of acute myeloid leukemia cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125195.RAbZx99vP0YCDRRFAZYoZnKQOkvAykea4GzSis1CtkoHs130_provenance.
- NP125197.RAStMeRzjwzqfwu6NAri2Eiw_g3EcgbDf0PCrd-3VazJg130_assertion description "[Mutated in acute myelocytic leukemia combined with acute lymphocytic leukemia in a case report.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125197.RAStMeRzjwzqfwu6NAri2Eiw_g3EcgbDf0PCrd-3VazJg130_provenance.
- NP125202.RAcbNfw8n2f80H_8F9qhFggQozqiicfQNYLDxNpNAKJ1g130_assertion description "[In contrast to children, adult acute myeloid leukemia cells do not express nonfunctional Ikaros isoforms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125202.RAcbNfw8n2f80H_8F9qhFggQozqiicfQNYLDxNpNAKJ1g130_provenance.
- NP125204.RAb8dpBEY_JPJG9mOkmfjQuN-6PdtK00Z3YuagPaKhJJQ130_assertion description "[The genotype distribution of the XRCC3 gene does not indicate a role for base excision repair in the development of therapy-related acute myeloblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125204.RAb8dpBEY_JPJG9mOkmfjQuN-6PdtK00Z3YuagPaKhJJQ130_provenance.
- NP125206.RAetZvuvPLr3YRJR4VA_n77c77iDRuV-e8VOr3k3b7pm8130_assertion description "[Bcl-2 is over-expressed in CD34+ acute myeloid leukemia (AML); conversely, MDR1 is over-expressed in CD34- AML.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125206.RAetZvuvPLr3YRJR4VA_n77c77iDRuV-e8VOr3k3b7pm8130_provenance.
- NP125218.RAa3awqRoPOB7klqYWmut-gozBrKW-xt_ECW_J_sQ9QnQ130_assertion description "[Blood levels are elevated in myelodysplastic syndromes and in acute myeloid leukemia/corrected for the peripheral blood platelet count is a marker of disease progression in MDS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125218.RAa3awqRoPOB7klqYWmut-gozBrKW-xt_ECW_J_sQ9QnQ130_provenance.
- NP125221.RATLCZmBhJevjKFYZ6-k7QxARXv51ghLSbXJBKijy_q6M130_assertion description "[up-regulated by the AML1-MTG8 fusion protein, suggesting a role in the granulocytic maturation characteristic of the t (8; 21) acute myelogenous leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125221.RATLCZmBhJevjKFYZ6-k7QxARXv51ghLSbXJBKijy_q6M130_provenance.
- NP125222.RARksfwShcwY855Ps_j2nBr3HoqVd_P2JKMe96hFflFAs130_assertion description "[analysis of the role of deregulated PcG genes in acute myeloid leukemia, and the downstream PcG targets HOXA4, HOXA9 and MEIS1 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125222.RARksfwShcwY855Ps_j2nBr3HoqVd_P2JKMe96hFflFAs130_provenance.
- NP125225.RAUR-ba52SuQuRMFIciejFbfimQCjsq7OmSoUvhl0SE_M130_assertion description "[Determination of P-glycoprotein, MDR-related protein 1, breast cancer resistance protein, and lung-resistance protein expression in leukemic stem cells of acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125225.RAUR-ba52SuQuRMFIciejFbfimQCjsq7OmSoUvhl0SE_M130_provenance.
- NP125226.RAV4ftggtheFtpjCZNK_E9E1BSe45CL4Nt7IkxSKbJCLk130_assertion description "[Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125226.RAV4ftggtheFtpjCZNK_E9E1BSe45CL4Nt7IkxSKbJCLk130_provenance.
- NP125229.RAVWYq9shrANSQ7jrxUJCh0pOjPR7atRu3SyPck4JI8zk130_assertion description "[MLL-CBL fusion was the result of an interstitial deletion in patients with de novo acute myeloid leukemia (FAB-M1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125229.RAVWYq9shrANSQ7jrxUJCh0pOjPR7atRu3SyPck4JI8zk130_provenance.
- NP125231.RAYVnEQkwaKBL62kGAy4HUzSgDzO7pPjZ8HCO0cW4vb-8130_assertion description "[C/EBPdelta is a novel tumor suppressor gene in acute myeloid leukemia that is silenced by promoter methylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125231.RAYVnEQkwaKBL62kGAy4HUzSgDzO7pPjZ8HCO0cW4vb-8130_provenance.
- NP125234.RAT1OAUICYx6TOXr_nh70fyMfyWnLsz69-jyDvhCvgslc130_assertion description "[Methylation of p15INK4B is associated with myelodysplasia and acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125234.RAT1OAUICYx6TOXr_nh70fyMfyWnLsz69-jyDvhCvgslc130_provenance.
- NP125237.RAeyFLwF-9PlZ-l5gHev7NbAJqE4xt5m5OK-8P9KNvTwI130_assertion description "[The IL-8 is increased of native human acute myelogenous leukemia (AML) blasts and nonleukemic cells in the bone marrow microenvironment seem important both for disease development chemosensitivity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125237.RAeyFLwF-9PlZ-l5gHev7NbAJqE4xt5m5OK-8P9KNvTwI130_provenance.
- NP125240.RAWz59NVi7syw-5r4yS-3wm2XwNCLZ9Eif9yosWV-UxH4130_assertion description "[Acute myelocytic leukemia patienets with elevated IGFBP2 concentrations had a poorer outcome after sten cell transplantation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125240.RAWz59NVi7syw-5r4yS-3wm2XwNCLZ9Eif9yosWV-UxH4130_provenance.
- NP125242.RARL5bCChHiCm05-bxTSnQV7BsZ7OIBM0_P19Vd33PQ4A130_assertion description "[Loss of PRAME is associated with childhood acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125242.RARL5bCChHiCm05-bxTSnQV7BsZ7OIBM0_P19Vd33PQ4A130_provenance.
- NP125248.RAct8zf-iE3LY9c4RDvzNFv5gxTevQiV-tJS8B7OqcE8I130_assertion description "[CEBPa is a target for MiR-124a in acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125248.RAct8zf-iE3LY9c4RDvzNFv5gxTevQiV-tJS8B7OqcE8I130_provenance.
- NP125255.RAeiWh52MfUfqaeF42WjTK5gKPwaPGej3Q8FJxNlu31XE130_assertion description "[The genotype distribution of the NQO1 gene does not indicate a role for base excision repair in the development of therapy-related acute myeloblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125255.RAeiWh52MfUfqaeF42WjTK5gKPwaPGej3Q8FJxNlu31XE130_provenance.
- NP125260.RAVaTG8joKuSxOtg3jfpw2CMSU-fh22Ad8py4Ve3_IJKI130_assertion description "[The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125260.RAVaTG8joKuSxOtg3jfpw2CMSU-fh22Ad8py4Ve3_IJKI130_provenance.
- NP125263.RASf9-n9HrzSmoZ2zJGmblrpZ_kMPovxYg4thfOZe8oEg130_assertion description "[CD96 is a cell surface marker present on many acute myeloid leukemia leukemic stem cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125263.RASf9-n9HrzSmoZ2zJGmblrpZ_kMPovxYg4thfOZe8oEg130_provenance.
- NP125268.RAQx45etpOVBUvNfVUWJjojhld6V2EoDRLSBybsL4QuRw130_assertion description "[Analysus if 2502 patients with acute myeloid leukemia at diagnosis for NRAS mutations around hot spots at codons 12, 13, and 61 and correlation of the the results with cytomorphology, cytogenetics, other molecular markers, and prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125268.RAQx45etpOVBUvNfVUWJjojhld6V2EoDRLSBybsL4QuRw130_provenance.
- NP125272.RAQq7dCh686FbPcYpY_NAHH0Sq3BDNI_QC2wT367g-ypc130_assertion description "[CYP1A1*2a may have a role in progression of acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125272.RAQq7dCh686FbPcYpY_NAHH0Sq3BDNI_QC2wT367g-ypc130_provenance.
- NP125274.RAaByRhXBjnnEXnuVEJ5UwOfz7Vmm9f1wYbyVJcRBnFVk130_assertion description "[NUR77 is a critical tumor suppressor of myeloid leukemogenesis that is downregulated in leukemic blasts from acute myeloid leukemia patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125274.RAaByRhXBjnnEXnuVEJ5UwOfz7Vmm9f1wYbyVJcRBnFVk130_provenance.
- NP125276.RAWuKS2YBQWHgNQiVujI6jrbhrrgj2Y2_AojMZz6Ap1ZU130_assertion description "[Abundant expression of fibronectin is a major feature of leukemic dendritic cells differentiated from patients with acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125276.RAWuKS2YBQWHgNQiVujI6jrbhrrgj2Y2_AojMZz6Ap1ZU130_provenance.
- NP125279.RAU3v-Rb0vXkbUsWvIwMfpdmvgQNrPcNuGIOX9ogoXEqA130_assertion description "[overexpressed in acute myelogenous leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125279.RAU3v-Rb0vXkbUsWvIwMfpdmvgQNrPcNuGIOX9ogoXEqA130_provenance.
- NP125285.RAaDFDIKimdQMrNPxeMcnS6AR2b_zMFsktjO9iyDMwIu4130_assertion description "[Aberrant regulation of STAT5 has been observed in solid tumors as well as in patients with either chronic or acute myeloid leukemia [review].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125285.RAaDFDIKimdQMrNPxeMcnS6AR2b_zMFsktjO9iyDMwIu4130_provenance.
- NP125289.RAebLTAIoCVfGqxN6MpHzkWLgyelx2utZeZLFCHZPKNoU130_assertion description "[Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125289.RAebLTAIoCVfGqxN6MpHzkWLgyelx2utZeZLFCHZPKNoU130_provenance.
- NP125291.RAbw4vr68m5MH23zg5lP_bLBr8YsM0dFkB75TnMSPGMfg130_assertion description "[study shows that NUP98-NSD1 induces acute myeloid leukemia in vivo, sustains self-renewal of myeloid stem cells in vitro, and enforces expression of the HoxA7, HoxA9, HoxA10 and Meis1 proto-oncogenes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125291.RAbw4vr68m5MH23zg5lP_bLBr8YsM0dFkB75TnMSPGMfg130_provenance.
- NP125293.RAdYcNWM3SU5NIQ6a5dVsXGc4q6TUTFtAMjjse5WT3VYs130_assertion description "[Loss of dcc gene expression is associated with acute myelogenous leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125293.RAdYcNWM3SU5NIQ6a5dVsXGc4q6TUTFtAMjjse5WT3VYs130_provenance.
- NP125295.RAZFUx3-0ZcZqXrZmCPojkby6uWEuyDwwTUqtGK3NXye8130_assertion description "[Higher endogenous VEGFC levels of acute myeloid leukemia cells are related to decreased in vitro and in vivo drug responsiveness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125295.RAZFUx3-0ZcZqXrZmCPojkby6uWEuyDwwTUqtGK3NXye8130_provenance.
- NP125296.RAY1PVx-BlojquSV-JKLVarC7019_Uff8r91uoVhPQQFI130_assertion description "[upregulated significantly in acute myeloid leukemia patients whose white blood cell count was higher than 100 x 10 (9)/L cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125296.RAY1PVx-BlojquSV-JKLVarC7019_Uff8r91uoVhPQQFI130_provenance.
- NP125298.RAe7GkS3NDNKwuwbqnLQ1tO0C_IdRR1a84bWCE2tzp8ok130_assertion description "[The chromosome translocation t (7; 11) (p15; p15) in acute myeloid leukemia results in fusion of the NUP98 gene with HOXA13.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125298.RAe7GkS3NDNKwuwbqnLQ1tO0C_IdRR1a84bWCE2tzp8ok130_provenance.
- NP125299.RATDUaHmH9bW7sajee4D_4kQ3tWq0wnpqxs3fshoXjxGA130_assertion description "[constitutive SHP2 activation synergizes with HoxA10 overexpression to accelerate progression to acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125299.RATDUaHmH9bW7sajee4D_4kQ3tWq0wnpqxs3fshoXjxGA130_provenance.
- NP125310.RAb8s6NZtJ0mAfdY9edGGmoqkCWJ3fECPf-qPmOd6cGhE130_assertion description "[The t (7; 11) (p15; p15) translocation, observed in acute myelogenous leukemia and myelodysplastic syndrome, generates a chimeric gene where the 5'portion of the sequence encoding the human nucleoporin NUP98 protein is fused to the 3'region of HOXA9.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125310.RAb8s6NZtJ0mAfdY9edGGmoqkCWJ3fECPf-qPmOd6cGhE130_provenance.
- NP125313.RARvaYFEZX-Q4Es806lFQfj9c_qSFcZsVKEBZntV38aLE130_assertion description "[The mutational status of the FLT3 tyrosine kinase domain (FLT3-TLD) in 3082 patients with newly diagnosed acute myeloid leukemia, was characterized.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125313.RARvaYFEZX-Q4Es806lFQfj9c_qSFcZsVKEBZntV38aLE130_provenance.
- NP125314.RAZ1TUgfaLCJgZTeox9_vRR-X2KYRaJLxkVijB-Bz_XFk130_assertion description "[Activating mutations of FLT3 is associated with acute myelogenous leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125314.RAZ1TUgfaLCJgZTeox9_vRR-X2KYRaJLxkVijB-Bz_XFk130_provenance.
- NP125315.RAUQHpvrXU8L-Xh4SjmuYbuu5uApgYp5M87hhzCqpK9Ps130_assertion description "[Elderly patients (range 60-85 yr) with acute myeloid leukemia carrying Flt3 internal tandem duplications (ITD) have a significant worse overall survival compared to Flt3-ITD wildtype patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125315.RAUQHpvrXU8L-Xh4SjmuYbuu5uApgYp5M87hhzCqpK9Ps130_provenance.
- NP125318.RAREMXGbJg7Cu_x38jHfwKt1JW44L_DWpq8tJUsZOmaYg130_assertion description "[This protein, which is mutated in majority of cases of acute myeloid leukemia, is used as an example or a method which may apply to the quantitation of several other proteins without the need for intact cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125318.RAREMXGbJg7Cu_x38jHfwKt1JW44L_DWpq8tJUsZOmaYg130_provenance.
- NP125328.RAZLYAYZRgcO5ya4rQ2duYjygeVlA9RysdixipXzgjcgA130_assertion description "[Unfavorable clinical implications for HLA-G expression in acute myeloid leukemia are reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125328.RAZLYAYZRgcO5ya4rQ2duYjygeVlA9RysdixipXzgjcgA130_provenance.
- NP125330.RAW5CtvU0tYkZFdOeyIWxsAYcNYxjH1-UFlLStV49IeGs130_assertion description "[In the Acute Myeloid Leukemia patients, detected MLL rearrangements consisting of MLL/AF6, MLL/AF9, MLL/AF17, MLL/ELL and MLL partial tandem duplication/rearrangement include chromosome translocation and partial tandem duplication.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125330.RAW5CtvU0tYkZFdOeyIWxsAYcNYxjH1-UFlLStV49IeGs130_provenance.
- NP125333.RAbO7XlZZ6Vo2x4qdADcA3klOMMrFNVd8LiI_eSt_ph7s130_assertion description "[The myelodysplastic syndrome patients, bearing the deletion, rapidly evolved to acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125333.RAbO7XlZZ6Vo2x4qdADcA3klOMMrFNVd8LiI_eSt_ph7s130_provenance.
- NP125334.RAfpHzFbc3DJiY7mgCKQQGpnnI-GahlNv0MHGVpqHpYCc130_assertion description "[FLT3 overexpression is associated with acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125334.RAfpHzFbc3DJiY7mgCKQQGpnnI-GahlNv0MHGVpqHpYCc130_provenance.
- NP125336.RAYW8jOvk7kCA3T_tL2zPe9PkCReVoPZrlKGnQMe3YAPA130_assertion description "[Activated FLT3 cooperates with MLL-AF9 to accelerate onset of acute myelogenous leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125336.RAYW8jOvk7kCA3T_tL2zPe9PkCReVoPZrlKGnQMe3YAPA130_provenance.
- NP125344.RAX09JveFN4lgpecfVkFKxyMYf86mw2aG3za_YZJRNEqE130_assertion description "[AML1-ETO and JAK2 may have a role in leukemogenesis, as shown by a myeloproliferative syndrome progressing to acute myeloid leukemia [case report]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125344.RAX09JveFN4lgpecfVkFKxyMYf86mw2aG3za_YZJRNEqE130_provenance.
- NP125346.RAdJTwlp90pxdlAFtCDVKKMS7PFr482nCCC5wWmFOjptM130_assertion description "[found ABC transporter A3 to be expressed consistently in acute myeloid leukemia samples/expression of ABCA3 is associated with unfavorable treatment outcome, and in vitro, elevated expression induces resistance to a broad spectrum of cytostatics ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125346.RAdJTwlp90pxdlAFtCDVKKMS7PFr482nCCC5wWmFOjptM130_provenance.
- NP125347.RAR1GWkvawNJeXQBbFkNYp8EgQLml7j0vUvoYZZNAV_vU130_assertion description "[CD13 was expressed in 73% of acute myeloid leukemia patients, CD15 was expressed in 43% of patients, CD33 was expressed in 64% of patients, and CD34 was expressed in 66% of patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125347.RAR1GWkvawNJeXQBbFkNYp8EgQLml7j0vUvoYZZNAV_vU130_provenance.
- NP125356.RAcIrZ0UUFg7SmwhbR8OeFhKNtF_-SKXG7BvF9FR6FCHM130_assertion description "[Median survival time of cytoplasmic CD79 alpha positive group was shorter than that of cytCD79a negative group in acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125356.RAcIrZ0UUFg7SmwhbR8OeFhKNtF_-SKXG7BvF9FR6FCHM130_provenance.
- NP125357.RAdVgvtuAnHjdpyp4Q4BsZTfq9CVgV4t4-36Fw6Ghx1Qk130_assertion description "[Differential effects of FGF4, EGF and TGFB1 on functional development of stromal layers (progenitor cell-outputs) in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125357.RAdVgvtuAnHjdpyp4Q4BsZTfq9CVgV4t4-36Fw6Ghx1Qk130_provenance.
- NP125371.RAVRXMHrrGnG9H0FhkbJ_6f9KT7KtLaEowKl49K0omrJ8130_assertion description "[correlation between expression of VEGF and p27 (Kip1) was observed in bone marrows from patients with acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125371.RAVRXMHrrGnG9H0FhkbJ_6f9KT7KtLaEowKl49K0omrJ8130_provenance.
- NP125375.RAVYCqo6dyYGauNA4-RQ8h-vQegysN8FbXw-l6XdsyJqc130_assertion description "[The use of reverse-transcription polymerase chain reaction for the detection of the PML-RARA and RARA-PML fusion genes that allow for monitoring of acute myelocytic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125375.RAVYCqo6dyYGauNA4-RQ8h-vQegysN8FbXw-l6XdsyJqc130_provenance.
- NP125380.RAZi3kfmo3Kuko95NZ6hi8rR94tWSN3x8yMrtq72jvemk130_assertion description "[secretion from acute myelogenous leukemia blasts was up-regulated by leptin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125380.RAZi3kfmo3Kuko95NZ6hi8rR94tWSN3x8yMrtq72jvemk130_provenance.
- NP125381.RAQS9Wn7-I95kO68nTCWTv2CUxnIR_pp-NkopM6W_SuL8130_assertion description "[plasma levels of adiponectin and TNFalpha are upregulated in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125381.RAQS9Wn7-I95kO68nTCWTv2CUxnIR_pp-NkopM6W_SuL8130_provenance.
- NP125384.RASiMJJboszOZ_hYip5L42pX3ukWnlAuTZuBwzQKMusGo130_assertion description "[ERC1-PDGFRB fusion is associated with acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125384.RASiMJJboszOZ_hYip5L42pX3ukWnlAuTZuBwzQKMusGo130_provenance.
- NP125385.RAX4dTu-kBW_JChfkh8-WCK9aK0mj61jbgUnj3k1Xte0g130_assertion description "[FANCD2 mutations were also common in Microsatellite instability+ Therapy-related acute myeloid leukemia/myelodysplastic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125385.RAX4dTu-kBW_JChfkh8-WCK9aK0mj61jbgUnj3k1Xte0g130_provenance.
- NP125391.RAS2yrXEcv93AdGxuxhgxlMbwt467omF0i7yPyzuvtzks130_assertion description "[TNFalpha- and FasL-stimulated acute myeloid leukemia cell lytic induction is regulated by a signalling pathway involving sequentially, radical oxygen species generation, Trx oxidation, ASK1 activation, p38MAPK stimulation and GrB induction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125391.RAS2yrXEcv93AdGxuxhgxlMbwt467omF0i7yPyzuvtzks130_provenance.
- NP125395.RARdiFqCjcuuDVKVkIrjTNse9lF-GQPVJDnYDE3nHoIpQ130_assertion description "[Overexpression of KIS protein kinase is associated with acute myelogenous leukemia, myelodysplastic syndrome and acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125395.RARdiFqCjcuuDVKVkIrjTNse9lF-GQPVJDnYDE3nHoIpQ130_provenance.
- NP125404.RARmctZtMQuqgMFQDj-0xvKY-7bOqAA-kO93zduiCwS18130_assertion description "[BCL11B is involved in hematological neoplasms of T-cells but not acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125404.RARmctZtMQuqgMFQDj-0xvKY-7bOqAA-kO93zduiCwS18130_provenance.
- NP125409.RAbDb2fOhtB4bc-Jh05TOc9zCvL82FvkymAUPgdQu3yLo130_assertion description "[TRAIL-R2 downmodulation results in resistance to TRAIL-mediated apoptosis in acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125409.RAbDb2fOhtB4bc-Jh05TOc9zCvL82FvkymAUPgdQu3yLo130_provenance.
- NP125411.RAf5ElWXx6qbeNdtypePDZb6P4jORwp5CDnE0Y9eaO7EY130_assertion description "[AML1 point mutation is one of the major driving forces of myelodysplastic syndrome and acute myeloid leukemia, and these mutations may represent a distinct clinicopathologic-genetic entity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125411.RAf5ElWXx6qbeNdtypePDZb6P4jORwp5CDnE0Y9eaO7EY130_provenance.
- NP125416.RAS4G8QbR5F8l5h1CKVxeG1GLq_YT9pyr4lbI4jjJWmVw130_assertion description "[C-terminal truncated AML1 mutant (S291fsX300) induced pancytopenia with erythroid dysplasia in transplanted mice, followed by progression to Myelodysplastic syndrome or acute myelogenous leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125416.RAS4G8QbR5F8l5h1CKVxeG1GLq_YT9pyr4lbI4jjJWmVw130_provenance.
- NP125418.RAYKgmC_aFRwEP98rr4jzptrJmrivYG0jl7TRdjsFAj6M130_assertion description "[MMP-9 abnormal expression may play a role in the increased vessel density notoriously found in bone marrow of acute myeloid leukemia (AML) patients at diagnosis and thus it may be involved in the leukemogenic process and in myelodysplastic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125418.RAYKgmC_aFRwEP98rr4jzptrJmrivYG0jl7TRdjsFAj6M130_provenance.
- NP125423.RAX_IGe_hhIHmheyLNoR5n4_c1iNsA4HHFo1STaqzxnEA130_assertion description "[transcription mediated by AML1 is impaired by mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125423.RAX_IGe_hhIHmheyLNoR5n4_c1iNsA4HHFo1STaqzxnEA130_provenance.
- NP125426.RAdECIyynO_MjGqmtYkVNGYLLl-lNrDVRQJ5nLZQLatTQ130_assertion description "[Increased CD69 of T lymphocytes, along with abnormally elevated immunologically active molecules play an important role in immune pathogenesis of patients with myelodysplastic syndrome (MDS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125426.RAdECIyynO_MjGqmtYkVNGYLLl-lNrDVRQJ5nLZQLatTQ130_provenance.
- NP125427.RAb8FDvueQyo6HDlczMturXolGzFbOV-_d4BEgAuuNOiI130_assertion description "[Lack of glutathione S-transferase M1 is associated with aplastic anemia and myelodysplastic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125427.RAb8FDvueQyo6HDlczMturXolGzFbOV-_d4BEgAuuNOiI130_provenance.
- NP125431.RAYJl-EArKKZjxzRaaR3M5RxS509rTRMeZXmhF9Vzoxfo130_assertion description "[among the 101 myelodysplastic syndromes patients in our cohort, we detected JAK2 mutations ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125431.RAYJl-EArKKZjxzRaaR3M5RxS509rTRMeZXmhF9Vzoxfo130_provenance.
- NP125435.RAfi_R8qCi0ik1q6gxLDpbPUeoOcyZ2fWqKZxe-sS32cE130_assertion description "[TRAIL has a role in the anemia of myelodysplastic syndromes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125435.RAfi_R8qCi0ik1q6gxLDpbPUeoOcyZ2fWqKZxe-sS32cE130_provenance.
- NP125437.RARoBMAQpRXQS68URrCr3V_blrGhESRAkWOL-hhhbufC0130_assertion description "[CD34 may have a role in apoptosis and drug resistance in acute myeloid leukemia and myelodysplastic syndromes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125437.RARoBMAQpRXQS68URrCr3V_blrGhESRAkWOL-hhhbufC0130_provenance.
- NP125444.RAd5UyUdzBtK54O7nenpGdz6YFSUNwA6lSpyAfFRgo8TY130_assertion description "[Unregulated activation of STAT-5, ERK1/2 and c-Fos may contribute to the phenotypic transformation from myelodysplastic syndrome to acute leukaemia/ERK1/2 signalling pathways were activated only by GM-CSF but not by Epo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125444.RAd5UyUdzBtK54O7nenpGdz6YFSUNwA6lSpyAfFRgo8TY130_provenance.
- NP125447.RARVNnem2qqf-CUQagdfV-twH8wN_iifHq5y3OIsOJUnM130_assertion description "[Novel variant involved in induction of cell proliferation; myelodysplastic syndrome; a deletion of three nucleotides (2128-2130) in the juxtamembrane domain of the G-CSFR resulted in a conversion of Asn (630) Arg (631) to Lys (630).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125447.RARVNnem2qqf-CUQagdfV-twH8wN_iifHq5y3OIsOJUnM130_provenance.
- NP125450.RAVp7zb_w6tglUh-byijgW7Bs17nLBLK_bS9tElXh8jbc130_assertion description "[MNDA has a role regulating programmed cell death in myeloid progenitor cells, and that its down-regulation in myelodysplastic syndromes is related to granulocyte-macrophage progenitor cell sensitivity to TRAIL-induced programmed cell death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125450.RAVp7zb_w6tglUh-byijgW7Bs17nLBLK_bS9tElXh8jbc130_provenance.
- NP125453.RAXEF0C69hshEw5XwD9cGA3sMg_cjKUbdr7cm989BLu40130_assertion description "[The RAP1B gene mutation is a rare event in myelodysplastic syndromes (MDS) bone marrow cells, in detecting RAP1B mutations, random mutagenesis was performed in RAP1B exons 2 and 3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125453.RAXEF0C69hshEw5XwD9cGA3sMg_cjKUbdr7cm989BLu40130_provenance.
- NP125455.RAehv1kUUAQZt6WKLxyTtuCB39Gr-9EbpYfuXoEpne-50130_assertion description "[Data suggest that Dido might be one of the tumor suppressor genes at chromosome 20q and that the Dido-targeted mouse may be a suitable model for studying myeloproliferative diseases and myelodysplastic syndromes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125455.RAehv1kUUAQZt6WKLxyTtuCB39Gr-9EbpYfuXoEpne-50130_provenance.
- NP125460.RAfll-UR1zuxb36SQvrujr34hrlF6_gxkO8ODUlXckHCg130_assertion description "[The PTPN11 protein mutation can be acquired during progression of myelodysplastic syndrome JMML.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125460.RAfll-UR1zuxb36SQvrujr34hrlF6_gxkO8ODUlXckHCg130_provenance.
- NP125464.RAVCFPfzrDOL6lTCHvZ0SrGaA5R1MsoVi5UfvfxvG3qn0130_assertion description "[The expression of mRNA for MDR1 and LRP was determined in bone marrow samples from control, de novo acute myelocytic leukemia, myelodysplastic syndrome (MDS), MDS at the time of overt leukemia (OL) transformation (MDS -- > OL), and after transformation (OL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125464.RAVCFPfzrDOL6lTCHvZ0SrGaA5R1MsoVi5UfvfxvG3qn0130_provenance.
- NP125465.RAT5B3vAW5jhxW2affNAWjOx6k8lQd3qkkv8UtGDA39p0130_assertion description "[The emergence of a mutation in this protein is involved in the clonal evolution of myelodysplastic syndromes towards secondary acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125465.RAT5B3vAW5jhxW2affNAWjOx6k8lQd3qkkv8UtGDA39p0130_provenance.
- NP125471.RAQkS2-bwR2d4MJVYSmL2brn1Pd5FEf0mkiyEX5Ilj8jo130_assertion description "[overexpression of IGF-IR exists in hematopoietic cells in myelodysplastic syndrome and acute myeloid leukemia marrows, which appears to contribute to disease progress ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125471.RAQkS2-bwR2d4MJVYSmL2brn1Pd5FEf0mkiyEX5Ilj8jo130_provenance.
- NP125476.RATsaU3nFm8W1jFvqdfCQo8NFZ589oNYjW8ruNeCBSVic130_assertion description "[series of novel point mutations in ATRX detected in archival DNA samples from marrow and/or blood of patients with myelodysplastic syndrome associated with alpha-thalassemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125476.RATsaU3nFm8W1jFvqdfCQo8NFZ589oNYjW8ruNeCBSVic130_provenance.
- NP125478.RAXthsA1-QJTyNlD5cebdNlp_K6EY9gZgXprR3qKwcpf0130_assertion description "[Blood levels are elevated in myelodysplastic syndromes and in acute myeloid leukemia/corrected for the peripheral blood platelet count is a marker of disease progression in MDS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125478.RAXthsA1-QJTyNlD5cebdNlp_K6EY9gZgXprR3qKwcpf0130_provenance.
- NP125479.RAVTV7XEcl8ktLmX0acJ4CvuxUwTusXmUWB6T2HhUJg5s130_assertion description "[The Vascular Endothelial Growth Factor is expressed in bone marrow cells in patients with myelodysplastic syndromes (MDS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125479.RAVTV7XEcl8ktLmX0acJ4CvuxUwTusXmUWB6T2HhUJg5s130_provenance.
- NP125484.RASeOLivtOGd-3365-9GKF7bJecuxW53ftrAeNYlIhA7A130_assertion description "[Data propose that over-expression of RAP1GAP gene may play a role in the pathogenesis of myelodysplastic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125484.RASeOLivtOGd-3365-9GKF7bJecuxW53ftrAeNYlIhA7A130_provenance.
- NP125485.RAeYa2VqNt3yy3LU5S5aLTbP1InaFFThnbo07QfaGl1I8130_assertion description "[Aberrant DNA methylation of frizzled 9 protein is associated with myelodysplastic syndrome progression to acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125485.RAeYa2VqNt3yy3LU5S5aLTbP1InaFFThnbo07QfaGl1I8130_provenance.
- NP125495.RAeYPwEMemVBwQOsaLRJAqtSAcNXWTeXNs7-oiirsaUjc130_assertion description "[FLT3 internal tandem repeat is associated with a high probability of evolution of myelodysplastic syndrome to acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125495.RAeYPwEMemVBwQOsaLRJAqtSAcNXWTeXNs7-oiirsaUjc130_provenance.
- NP125496.RAW08nNo6jJEqS-Mn94j0Waog_kvFH7uZEMlNdRpaUO0Y130_assertion description "[High expression of ERCC1, FLT1, NME4 and PCNA in myelodysplastic syndrome was associated with poor prognosis and disease progression along the sequence of 5q-syndrome/RCMD/RAEB/de novo AML ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125496.RAW08nNo6jJEqS-Mn94j0Waog_kvFH7uZEMlNdRpaUO0Y130_provenance.
- NP125501.RAYcVCI_8m1-Iz849nWUYAnWluUW3NhQVB67l66uLrBPg130_assertion description "[GAB2 is a novel target of 11q amplification in acute myeloid leukemia and myelodysplastic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125501.RAYcVCI_8m1-Iz849nWUYAnWluUW3NhQVB67l66uLrBPg130_provenance.
- NP125518.RAYF30Vt3OFKdQkBlfx790ZYUk11eRrc0M7K4Bqwowr4s130_assertion description "[Lack of glutathione S-transferase theta 1 is associated with aplastic anemia and myelodysplastic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125518.RAYF30Vt3OFKdQkBlfx790ZYUk11eRrc0M7K4Bqwowr4s130_provenance.
- NP125523.RAcd1uQRy5Po_L5GfApO_q0Zxba1e6nMxb-Z5z8Dl24Xk130_assertion description "[Upregulation of iNOS in myelodysplastic syndromes has no significant correlation with apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125523.RAcd1uQRy5Po_L5GfApO_q0Zxba1e6nMxb-Z5z8Dl24Xk130_provenance.
- NP125526.RASWbm2KLlHAgWnRPYHyUochQkMxX9KY3i3aiJujm6K_s130_assertion description "[These data suggest that coexpression of the MET and RON receptors confer a selective advantage to ovarian cancer cells and might promote ovarian cancer progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125526.RASWbm2KLlHAgWnRPYHyUochQkMxX9KY3i3aiJujm6K_s130_provenance.
- NP125529.RARwR3MmGRXpkH7s00mcHtSvJWL0OB5EHmS6IHEld_ZT8130_assertion description "[In ovarian cancer there is a dramatic decrease of HtrA3 mRNA and protein levels in all ovarian tumor groups; HtrA3 may function as a tumor suppressor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125529.RARwR3MmGRXpkH7s00mcHtSvJWL0OB5EHmS6IHEld_ZT8130_provenance.
- NP125530.RAYN6NTygXPJxEiv5B83MlvAIDjdU3nwzfYQ485vs72yo130_assertion description "[insulin receptor may play a role in the regulation of ovarian cancer cell growth ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125530.RAYN6NTygXPJxEiv5B83MlvAIDjdU3nwzfYQ485vs72yo130_provenance.