Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP125532.RAd_x2Cxby9wTB6L5tcjIpp-_O-iaxB0GUL9l1nUA8M1o130_assertion description "[Serum CA125 was significantly higher in patients with ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125532.RAd_x2Cxby9wTB6L5tcjIpp-_O-iaxB0GUL9l1nUA8M1o130_provenance.
- NP125535.RAcvWT35qOkqlEIKZTvp4VoHiz4r63Q4U7XOgpQ9A4I2Q130_assertion description "[Higher blood levels may be indicative of ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125535.RAcvWT35qOkqlEIKZTvp4VoHiz4r63Q4U7XOgpQ9A4I2Q130_provenance.
- NP125549.RAeQISdI2pv4G9nhfmhjuQdOEFauLfxzuMMS2f1Uls95s130_assertion description "[Caspase-3-dependent activation of calcium-independent phospholipase A2 enhances cell migration in non-apoptotic ovarian cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125549.RAeQISdI2pv4G9nhfmhjuQdOEFauLfxzuMMS2f1Uls95s130_provenance.
- NP125556.RAUelqj-EbJ7P2_XiHBuBANJ1ZiW-YW-phF1iEWp7OOKU130_assertion description "[Our study shows that LPAAT-beta is upregulated in ovarian cancer and is more prevalent in poorly differentiated tumours ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125556.RAUelqj-EbJ7P2_XiHBuBANJ1ZiW-YW-phF1iEWp7OOKU130_provenance.
- NP125563.RAcBOrPx91ubkSBkevR_xP19pJ_399VOQ_oPDR8h4d1TA130_assertion description "[Cyclin D1, p53, and p21Waf1/Cip1 have roles in progression of serous epithelial ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125563.RAcBOrPx91ubkSBkevR_xP19pJ_399VOQ_oPDR8h4d1TA130_provenance.
- NP125565.RAZdfE0UE-zClOH9dAgzj1JB6oy-km1qxnN2m7NDcHxUc130_assertion description "[The Expression of pygopus 2 protein mRNA levels were significantly higher in the epithelial ovarian cancer cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125565.RAZdfE0UE-zClOH9dAgzj1JB6oy-km1qxnN2m7NDcHxUc130_provenance.
- NP125570.RAWitOhRLz2kYZtW-jkIixlwvr6U1TstVd1U98O___srQ130_assertion description "[EGFR and TrkB crosstalk each other in response to EGF and BDNF, leading to cell survival pathway activation in ovarian cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125570.RAWitOhRLz2kYZtW-jkIixlwvr6U1TstVd1U98O___srQ130_provenance.
- NP125573.RAd600pEpHtxRawPeh7_l3csdAmKogVreW5Z-muJCslUA130_assertion description "[analysis of PAFR activation and pleiotropic effects on tyrosine phospho-EGFR/Src/FAK/paxillin in ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125573.RAd600pEpHtxRawPeh7_l3csdAmKogVreW5Z-muJCslUA130_provenance.
- NP125574.RAf21AEgnox8dwu_Fdv71wbVAo2VeqDMv_xf_2nBMVpv4130_assertion description "[analysis of activating mutations in catalytic domain of EGFR in 3.5% (2 of 57) of ovarian cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125574.RAf21AEgnox8dwu_Fdv71wbVAo2VeqDMv_xf_2nBMVpv4130_provenance.
- NP125579.RAUd0Gk0ZhOS4nCXLUtsaYZDKr9p4x4nYaSt7fJadQo-0130_assertion description "[we propose that HNF1beta overexpression in the ovarian cancer participates in the altered expression pattern ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125579.RAUd0Gk0ZhOS4nCXLUtsaYZDKr9p4x4nYaSt7fJadQo-0130_provenance.
- NP125589.RAUI6UfsWJwYLwWniteM7hT1HifscOFN5BbIkKUWqaclY130_assertion description "[study demonstrates that platelet-derived growth factor receptor alpha and beta, and c-kit protein are expressed in a high percentage of epithelial ovarian cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125589.RAUI6UfsWJwYLwWniteM7hT1HifscOFN5BbIkKUWqaclY130_provenance.
- NP125594.RAZoGzUIRFd0py2zc8CjpigyX3xZbL1qw4L6XtapBN9z0130_assertion description "[N-WASP plays a pivotal role in regulating hyaluronan-mediated CD44-ErbB2 interaction, beta-catenin signaling, and actin cytoskeleton functions that are required for tumor-specific behaviors and ovarian cancer progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125594.RAZoGzUIRFd0py2zc8CjpigyX3xZbL1qw4L6XtapBN9z0130_provenance.
- NP125598.RAQTJqIDJlmyqWKHHxKneh7gQ5a_-9O_J4LN_7HtBtCBg130_assertion description "[Overexpression of P-AKT and NF-kappaB p65 were involved in the carcinogenesis and metastasis of ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125598.RAQTJqIDJlmyqWKHHxKneh7gQ5a_-9O_J4LN_7HtBtCBg130_provenance.
- NP125599.RAQ2YFxozt--OrrQ2oBKfrW0EJD_grCTi_zFCXwViCsiE130_assertion description "[Jagged-1 is the primary Notch3 ligand in ovarian carcinoma and Jagged-1/Notch3 interaction constitutes a juxtacrine loop promoting proliferation and dissemination of ovarian cancer cells within the intraperitoneal cavity ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125599.RAQ2YFxozt--OrrQ2oBKfrW0EJD_grCTi_zFCXwViCsiE130_provenance.
- NP125602.RAbE5DTyGYFHTrEUfFzzDXPE4iaHnIyFaEmflJiCFnbgE130_assertion description "[Decreased/lost ALCAM membrane expression is a marker of poorer outcome in epithelial ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125602.RAbE5DTyGYFHTrEUfFzzDXPE4iaHnIyFaEmflJiCFnbgE130_provenance.
- NP125607.RAY-hQ5Rc8S4pnNQxwlBs-uPIhvpaNnybAk2ZU3B6CedE130_assertion description "[MTHFR polymorphism is associated with marked mtx-induced hyperhomocysteinemia in ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125607.RAY-hQ5Rc8S4pnNQxwlBs-uPIhvpaNnybAk2ZU3B6CedE130_provenance.
- NP125614.RAaOufiNkiuNwt4_1BDZPfI2B6aeXJtOnJCaAEiv-pUn4130_assertion description "[In ovarian metastases from undiagnosed colorectal adenocarcinomas, elevated CA-125 levels and frequent coexpression of cytokeratin 7 are features that can contribute to misclassification of these metastases as primary ovarian neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125614.RAaOufiNkiuNwt4_1BDZPfI2B6aeXJtOnJCaAEiv-pUn4130_provenance.
- NP125630.RASwKpFAAlK9tOzI5PO8RTceEztugVp2-7_AwqDfugtcM130_assertion description "[TNF-alpha is differentially regulated in ovarian cancer cells compared with untransformed cells and modulates production of several cytokines that may promote ovarian tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125630.RASwKpFAAlK9tOzI5PO8RTceEztugVp2-7_AwqDfugtcM130_provenance.
- NP125639.RAeTjwILDXKzE9_bthvZ8GsDMg7vlaJF7vDnhbbYHWrIs130_assertion description "[A significant MHC class I-restricted cytotoxic T-lymphocyte killing was demonstrated against Her-2/neu-positive ovarian cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125639.RAeTjwILDXKzE9_bthvZ8GsDMg7vlaJF7vDnhbbYHWrIs130_provenance.
- NP125646.RAS9PM0bz_q-L-O9-SBHl0gw3PzJWCFIcREeNgxTVac4U130_assertion description "[High cIAP membranous expression is associated with epithelial ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125646.RAS9PM0bz_q-L-O9-SBHl0gw3PzJWCFIcREeNgxTVac4U130_provenance.
- NP125647.RAcakeV8_3odOieZoIMWOxQ9xSEz88hmdsh2E2AhWeTkk130_assertion description "[data indicate that PPAR-gamma activation by selective agonists is a valid strategy for ovarian cancer therapy and prevention, and should be tested alone and in combination with other anticancer drugs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125647.RAcakeV8_3odOieZoIMWOxQ9xSEz88hmdsh2E2AhWeTkk130_provenance.
- NP125649.RAUpds4OnZftx6wH2LBXvssCwZ_-05wQWdFW_lgnorJQM130_assertion description "[B7-H4 mRNA and protein are overexpressed in human serous ovarian cancers and breast cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125649.RAUpds4OnZftx6wH2LBXvssCwZ_-05wQWdFW_lgnorJQM130_provenance.
- NP125651.RAQOXLZ74hvvgZ2reeKdHzXa78WVGhXFUpNSmyKo57q3o130_assertion description "[We investigated Emi1 protein expression in ovarian neoplasms ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125651.RAQOXLZ74hvvgZ2reeKdHzXa78WVGhXFUpNSmyKo57q3o130_provenance.
- NP125652.RAZeciadqI3kcFHil5iOWDIKLF6SEYrum3tnker0o4xYk130_assertion description "[Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125652.RAZeciadqI3kcFHil5iOWDIKLF6SEYrum3tnker0o4xYk130_provenance.
- NP125654.RAek5cj8QGqkjIj2yd3Z4iDkI4QuI4QegCtwfAc6sfJkA130_assertion description "[epigenetic silencing by hypermethylation of the CTGF promoter leads to a loss of CTGF function, which may be a factor in the carcinogenesis of ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125654.RAek5cj8QGqkjIj2yd3Z4iDkI4QuI4QegCtwfAc6sfJkA130_provenance.
- NP125658.RAVODYNnuCtD-dRNjd3NNijSLVxMVYTMbaHlXscoloo4g130_assertion description "[overexpression of the CHP2 gene affects the biological behavior of ovarian cancer cell line OVCAR3 and is one of key mechanisms for ovarian carcinoma progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125658.RAVODYNnuCtD-dRNjd3NNijSLVxMVYTMbaHlXscoloo4g130_provenance.
- NP125659.RAbvFtmzbGbcwz2K6T2dmgtuvE0OuND1ET8RQdt7Qc8OU130_assertion description "[CCL2 may play role in pathobiology of ovarian cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125659.RAbvFtmzbGbcwz2K6T2dmgtuvE0OuND1ET8RQdt7Qc8OU130_provenance.
- NP125669.RAXazs4aTOHM0QjPjihEJ-6NbRag2SzptgkKXajgS4q70130_assertion description "[This study demonstrates a novel mechanism of EGF-induced VEGF and HIF-1alpha expression through production of H2O2 and activation of AKT and p70S6K1 in human ovarian cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125669.RAXazs4aTOHM0QjPjihEJ-6NbRag2SzptgkKXajgS4q70130_provenance.
- NP125670.RAe00fsjQywElhFHO1eWMgb9ZcGFjxHE3QkS93oW4Aj8k130_assertion description "[high expression of this protein is associated with favorable ovarian cancer survival ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125670.RAe00fsjQywElhFHO1eWMgb9ZcGFjxHE3QkS93oW4Aj8k130_provenance.
- NP125673.RAQPqbryHC_at4Tu9ktI2UpwndvKDXAYwqXEdHL0iftQk130_assertion description "[PGRMC1 plays an important role in promoting ovarian cancer cell viability and that attenuating PGRMC1's action makes the ovarian cancer cells more sensitive to cisplatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125673.RAQPqbryHC_at4Tu9ktI2UpwndvKDXAYwqXEdHL0iftQk130_provenance.
- NP125674.RAYfcAvQMQpIUZDF_yu9JePIlESXZpwqjRfyn0xEhVrOw130_assertion description "[FLIP plays a significant role in the regulation of apoptosis in human ovarian cancer cells and their sensitivity to cisplatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125674.RAYfcAvQMQpIUZDF_yu9JePIlESXZpwqjRfyn0xEhVrOw130_provenance.
- NP125693.RAW0_WnkbP_OLKBgDGMwRIDnXhHkFydNzbsomr8Ev6keo130_assertion description "[Cyclooxygenase-2 (COX-2), epidermal growth factor receptor (EGFR), and Her-2/neu are expressed in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125693.RAW0_WnkbP_OLKBgDGMwRIDnXhHkFydNzbsomr8Ev6keo130_provenance.
- NP125698.RATPTwNhqbz80hKE5tV31STno1-_AnsPFB8HaXDxiDRQQ130_assertion description "[Upregulation of ERCC1 and XPD protein expression was associated with resistance process to platinum-based chemotherapy in advanced epithelial ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125698.RATPTwNhqbz80hKE5tV31STno1-_AnsPFB8HaXDxiDRQQ130_provenance.
- NP125699.RASTC62Pa3wQgI_dpc_a_bIqtq4PzK6e9vJp66k7tjf6M130_assertion description "[role of urokinase plasminogen activator receptor (uPAR) and c-erbB-2 in breast and ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125699.RASTC62Pa3wQgI_dpc_a_bIqtq4PzK6e9vJp66k7tjf6M130_provenance.
- NP125700.RARdS-WhnKsv0dX5r_GIeK7vR6QIKGuh9iwtetVNiQbv8130_assertion description "[procathepsin D interacts with prosaposin in human breast and ovarian cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125700.RARdS-WhnKsv0dX5r_GIeK7vR6QIKGuh9iwtetVNiQbv8130_provenance.
- NP125708.RAS5or7GtFFb-Evwnk3j1NABqFr2lhGVvS7et07FkGtq8130_assertion description "[Data show that p38 MAPK is necessary for HGF sensitization of ovarian cancer cells to low-doses of CDDP and PTX and might be sufficient to overcome activation of survival pathways.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125708.RAS5or7GtFFb-Evwnk3j1NABqFr2lhGVvS7et07FkGtq8130_provenance.
- NP125722.RAdBmJUClKltc5xNKuoZEJucmccXhQvW27ucOvencZm6k130_assertion description "[Epo has a role in reducing expression of apoptosis-related proteins Bcl-2 and Bcl-10 in ovarian cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125722.RAdBmJUClKltc5xNKuoZEJucmccXhQvW27ucOvencZm6k130_provenance.
- NP125724.RAaJ6TAxBwrXjc-iM9sicg7W9BPaeaYrqunu-Jb6HLDVY130_assertion description "[Overexpression of EphB4 is associated with ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125724.RAaJ6TAxBwrXjc-iM9sicg7W9BPaeaYrqunu-Jb6HLDVY130_provenance.
- NP125726.RAedLEmf3V2qIxDP2PNCLBM-U9Z4yW0QeSzkM56-FMoAw130_assertion description "[High tumor KLK6 protein expression is associated with inferior patient outcome in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125726.RAedLEmf3V2qIxDP2PNCLBM-U9Z4yW0QeSzkM56-FMoAw130_provenance.
- NP125728.RAax1Sca1AaFmCAjl2V4uiOY8KKGF6L0g-IQYVT17wx8U130_assertion description "[BRAF and MEK1/2 mutations may be more common than anticipated in ovarian cancer which could have important implications for treatment of patients with this disease and suggests potential new therapeutic avenues ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125728.RAax1Sca1AaFmCAjl2V4uiOY8KKGF6L0g-IQYVT17wx8U130_provenance.
- NP125730.RAbANCXBmXE36EnA0UtzA0gweww2p7JgWyRR9sMenCSY4130_assertion description "[regulation of human CD4+ IL-17-producing T cells in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125730.RAbANCXBmXE36EnA0UtzA0gweww2p7JgWyRR9sMenCSY4130_provenance.
- NP125731.RATYvkfhvqaxxd9qeFSNbtBT6tZEXgJTKbC_Mjl8ywUqM130_assertion description "[TSG101 negatively regulates p21 levels, and up-regulation of TSG101 is associated with poor prognosis in ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125731.RATYvkfhvqaxxd9qeFSNbtBT6tZEXgJTKbC_Mjl8ywUqM130_provenance.
- NP125732.RAQ6wLPG-TN14T9-3D_QZHhATLNpprUahTJpszHyN_6oE130_assertion description "[There is a functional relevance of DR4 expression in ovarian neoplasms, with perhaps a substantial contribution of DR4 hyper-methylation and consequent loss of DR4 expression to ovarian cancer pathogenesis, particularly in premenopausal patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125732.RAQ6wLPG-TN14T9-3D_QZHhATLNpprUahTJpszHyN_6oE130_provenance.
- NP125733.RAdND9jHYDUPub8xw2ZruihkC9U0953Po9YkBep0Kr7wQ130_assertion description "[Variants of the GSTM1 gene may modify the association between genital talc use and risk of total and serous invasive ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125733.RAdND9jHYDUPub8xw2ZruihkC9U0953Po9YkBep0Kr7wQ130_provenance.
- NP125737.RAUaajaAWR-HMTkbL9zzUsjY04_g6PDpsLW2bSXxV1-6s130_assertion description "[Integrin beta (3) Leu33Pro homozygotes have an increased risk of ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125737.RAUaajaAWR-HMTkbL9zzUsjY04_g6PDpsLW2bSXxV1-6s130_provenance.
- NP125739.RAVv95gouq-Xea_YEQ_wXRLJcoyxI5bHo2J6dY6G0plOg130_assertion description "[PEA-15 expression is an important prognostic marker in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125739.RAVv95gouq-Xea_YEQ_wXRLJcoyxI5bHo2J6dY6G0plOg130_provenance.
- NP125745.RAW8rddlDc6RkavuN0wIemDI61IiOuxJhfptk0q7BbDDU130_assertion description "[analysis of PIK3CA mutations in ovarian cancer [letter]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125745.RAW8rddlDc6RkavuN0wIemDI61IiOuxJhfptk0q7BbDDU130_provenance.
- NP125746.RASOsNVg4t9i6tVxDvXDfLGFun4ovk6kAuYPAQ_UuWV5I130_assertion description "[In ovarian metastases from undiagnosed colorectal adenocarcinomas, elevated CA-125 levels and frequent coexpression of cytokeratin 7 are features that can contribute to misclassification of these metastases as primary ovarian neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125746.RASOsNVg4t9i6tVxDvXDfLGFun4ovk6kAuYPAQ_UuWV5I130_provenance.
- NP125747.RAXKCzDH7wLhBwyhyINwpsE3swNShb99gEZjzd4au1PqE130_assertion description "[RNASET2 found to significantly decrease the metastatic potential of ovarian cancer cell line in vivo; tumor suppression by RNASET2 is suggested to not be mediated by its ribonuclease activity ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125747.RAXKCzDH7wLhBwyhyINwpsE3swNShb99gEZjzd4au1PqE130_provenance.
- NP125751.RAaLZTsejHSoY2CjamI7Ep7b-RVi60RhYhdqWX3tNJz94130_assertion description "[IL-8 expression is negatively linked to ER status of breast and ovarian cancer cells.IL-8 expression is associated with a higher invasiveness potential of cancer cells in vitro, which suggests that IL-8 could be a novel marker of tumor aggressiveness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125751.RAaLZTsejHSoY2CjamI7Ep7b-RVi60RhYhdqWX3tNJz94130_provenance.
- NP125755.RAU3tvwAdvVOhs14yApdCugsrLcQUPE7PfvxxC5A4JE_4130_assertion description "[Results suggest that epigenetic alterations in p15INK4b have an important role in ovarian carcinogenesis and that mechanisms other than methylation may exist to reduce gene expression of p15INK4b in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125755.RAU3tvwAdvVOhs14yApdCugsrLcQUPE7PfvxxC5A4JE_4130_provenance.
- NP125756.RAex43zxhD7VmW_C7eT-P-U-jh80yywo6PhRW6BYIfi8M130_assertion description "[Overexpression of antiapoptotic proteins Bcl-2 and Bcl-X (L) and down-regulation of caspase-3 activity may be associated with cisplatin resistance in human ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125756.RAex43zxhD7VmW_C7eT-P-U-jh80yywo6PhRW6BYIfi8M130_provenance.
- NP125762.RAQ5cmz3dsil90cu7zkc1yQUfCV_u4kcpmJNNzrv0G52E130_assertion description "[TSG101 negatively regulates p21 levels, and up-regulation of TSG101 is associated with poor prognosis in ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125762.RAQ5cmz3dsil90cu7zkc1yQUfCV_u4kcpmJNNzrv0G52E130_provenance.
- NP125764.RATdQ3SQmn1XNWmZLY_Lr9Tzrae8SueUZ_O8iJYhYUTmY130_assertion description "[serum starvation induces G1 arrest through suppression of Skp2-dependent CDK2 activity and Skp2-independent CDK4 activity in human SK-OV-3 ovarian cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125764.RATdQ3SQmn1XNWmZLY_Lr9Tzrae8SueUZ_O8iJYhYUTmY130_provenance.
- NP125766.RAe8lq-DzY8MRAheSi80xJhtPTeEVjfOw5l-ybVkSyGVw130_assertion description "[p53 appears to regulate EphA2 expression and clinical outcome in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125766.RAe8lq-DzY8MRAheSi80xJhtPTeEVjfOw5l-ybVkSyGVw130_provenance.
- NP125772.RAUydqfi68q68xkznEBMWqis7KAG6jfFrWXtKMlLy-dKI130_assertion description "[These results suggest that PEA3 is regulated by EGFR and that the elevated PEA3 expression detected in human ovarian cancer may divert cells to a more invasive phenotype by regulating MMP-9 and MMP-14.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125772.RAUydqfi68q68xkznEBMWqis7KAG6jfFrWXtKMlLy-dKI130_provenance.
- NP125773.RATXWs_vDew-6bUS1ePAIW2RBF2691Q_0oXbwCB8fdICE130_assertion description "[IL-7 levels were found to be strongly associated with ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125773.RATXWs_vDew-6bUS1ePAIW2RBF2691Q_0oXbwCB8fdICE130_provenance.
- NP125775.RAV19VI1K3byln7dbxdHSI1m0iN9eMsFE2hHkKz1HqVko130_assertion description "[results suggest that TCF2 is involved in the development of ovarian cancers and may represent a useful target for their detection and treatment ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125775.RAV19VI1K3byln7dbxdHSI1m0iN9eMsFE2hHkKz1HqVko130_provenance.
- NP125778.RAQqvOjHduB1LIhzXouK9kevSQZuXB-c_93HSWk-Udkdo130_assertion description "[Integrin-linked kinase functions as a downstream mediator of the ET-1/ET (A) R axis to potentiate aggressive cellular behavior in ovarian cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125778.RAQqvOjHduB1LIhzXouK9kevSQZuXB-c_93HSWk-Udkdo130_provenance.
- NP125788.RAehfJnoU2coQBkf7KkUJ6DWngWtHFPESJFp_GM817DHE130_assertion description "[Assays measuring HE4 in serum and other bodily fluids are likely to be clinically useful for patients with ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125788.RAehfJnoU2coQBkf7KkUJ6DWngWtHFPESJFp_GM817DHE130_provenance.
- NP125789.RAdDSQrEESZvBfkYSROmNiLgjtfiUCFe18Gn_f1YyMAlg130_assertion description "[Over-expression of CD24 is associated with primary and relapsed ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125789.RAdDSQrEESZvBfkYSROmNiLgjtfiUCFe18Gn_f1YyMAlg130_provenance.
- NP125795.RAb6t9Rsq2y9tvCsRtJEm4V-_FclxO_DIOOUrCDzs4ttI130_assertion description "[High expression of insulin-like growth factor binding protein-2 messenger RNA is associated with epithelial ovarian cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125795.RAb6t9Rsq2y9tvCsRtJEm4V-_FclxO_DIOOUrCDzs4ttI130_provenance.
- NP125798.RAcOk3q_4KbU77HhpSZA8E2IgUI2XuANCjn4PsSDYtnfg130_assertion description "[The G > A nt-93 variant of the MLH1 gene is associated with an increased risk of invasive ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125798.RAcOk3q_4KbU77HhpSZA8E2IgUI2XuANCjn4PsSDYtnfg130_provenance.
- NP125799.RARlZcriLVfbVJl1yzY6j4zt9_LUBgXT6SCqWC17qf4rU130_assertion description "[Frequent LOH at hMLH1, a highly variable SNP in hMSH3, and negligible coding instability occur in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125799.RARlZcriLVfbVJl1yzY6j4zt9_LUBgXT6SCqWC17qf4rU130_provenance.
- NP125800.RAYIq8anAEpUP5DZ85Q6mX0kjDP8inJ4NGeMVTK1_DtRk130_assertion description "[The immunohistochemical expression of hMLH1 and hMSH2 proteins in ovarian cancer has no predictive value in resistance to cisplatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125800.RAYIq8anAEpUP5DZ85Q6mX0kjDP8inJ4NGeMVTK1_DtRk130_provenance.
- NP125808.RAXW1TJKV5kuCV12063kkuZq0Jv0fP4qwNV5OoHhV7Ps8130_assertion description "[Insulin-degrading enzyme protein expression was found in normal tissues of the kidney, liver, lung, brain, breast and skeletal muscle, as well as in breast and ovarian cancer tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125808.RAXW1TJKV5kuCV12063kkuZq0Jv0fP4qwNV5OoHhV7Ps8130_provenance.
- NP125809.RAU5wlbYyJrLBZL2KZPCrLC1vNHyBXv50lFFhShwpRk6c130_assertion description "[class III beta-tubulin has a role in paclitaxel resistance in ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125809.RAU5wlbYyJrLBZL2KZPCrLC1vNHyBXv50lFFhShwpRk6c130_provenance.
- NP125820.RAaejv4t5OGBgTgWPz_ZAbhdSj0DrwJN0KHKk_LU3lOVI130_assertion description "[BRCA2 genomic rearrangements is associated with breast and ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125820.RAaejv4t5OGBgTgWPz_ZAbhdSj0DrwJN0KHKk_LU3lOVI130_provenance.
- NP125821.RASjhdBgoeO5uOeF8uBE65CjeoOtOmV6Xlw0YJGIXilM8130_assertion description "[Sixty-four Polish families with a history of breast and/or ovarian cancer were screened for mutations in the BRCA1/2 genes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125821.RASjhdBgoeO5uOeF8uBE65CjeoOtOmV6Xlw0YJGIXilM8130_provenance.
- NP125824.RAc2LsoGK5ctwQ46jGhkwhnGUMJ4OhVoIxCkSxjoF8ZZM130_assertion description "[Data indicate that BRCA2 are the major susceptibility genes for ovarian cancer but that other susceptibility genes may exist.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125824.RAc2LsoGK5ctwQ46jGhkwhnGUMJ4OhVoIxCkSxjoF8ZZM130_provenance.
- NP125828.RAR0mRB3VUIxuQ9VAat7cDokOS9qqXAnutihkxArieOkg130_assertion description "[truncated proteins arising from BRCA1 185delAG mutation increase Akt-mediated apoptosis, suggesting a possible mechanism by which ovarian cancer patients with this germline BRCA1 mutation may respond better to initial chemotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125828.RAR0mRB3VUIxuQ9VAat7cDokOS9qqXAnutihkxArieOkg130_provenance.
- NP125829.RAQVpDfGwm7L8k25svtrOhOCSeap9lGk0A-asmDzXsWN8130_assertion description "[one large deletion in BRCA1, deleting the most part of the gene (exon 1A-13) in one family with family history of ovarian cancer in Finland ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125829.RAQVpDfGwm7L8k25svtrOhOCSeap9lGk0A-asmDzXsWN8130_provenance.
- NP125840.RAaiicQQ102XJj8bQdIVQbvBd5ZNzGUAfKsVc6nDExANM130_assertion description "[There is a highly significant reduction in life expectancy in BRCA1 compared with BRCA2 carriers in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125840.RAaiicQQ102XJj8bQdIVQbvBd5ZNzGUAfKsVc6nDExANM130_provenance.
- NP125851.RAbMbDy7UYhEHhpJsS-gAkQdW31OhbrLue_QbI2WBV8Ys130_assertion description "[Aurora-A kinase is overexpressed by a substantial proportion of ovarian cancers and is associated with centrosome amplification and poor prognosis andsurvival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125851.RAbMbDy7UYhEHhpJsS-gAkQdW31OhbrLue_QbI2WBV8Ys130_provenance.
- NP125852.RAeEGy79wwxlICdAx3qN_diyNIbxnFI4TtvcmSvJsR0Mg130_assertion description "[Higher BTAK expression was found in ovarian cancer cells compared to ovaries without cancer but with known BRCA1/2 mutation or strong family history.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125852.RAeEGy79wwxlICdAx3qN_diyNIbxnFI4TtvcmSvJsR0Mg130_provenance.
- NP125871.RAZOEqY_uF1mfL9MXFhCrzDDFGiKNde4anPHydZ-9rbfM130_assertion description "[OPN promotes ovarian cancer progression and cell survival and increases HIF-1alpha expression through the PI3-K/Akt pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125871.RAZOEqY_uF1mfL9MXFhCrzDDFGiKNde4anPHydZ-9rbfM130_provenance.
- NP125872.RAdn_szMVIkb8pRY9zH-nGPhFm0lQfZtDDpoomh2MLE_c130_assertion description "[an association between levels of a biomarker, osteopontin, and ovarian cancer suggest its clinical usefulness ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125872.RAdn_szMVIkb8pRY9zH-nGPhFm0lQfZtDDpoomh2MLE_c130_provenance.
- NP125875.RASHgE0q3RGyE8nuQdqntpdVOxCWOY9dnIsckZyq-uHPk130_assertion description "[Oncogenic RAS activity is directly responsible for OPCML promoter hypermethylation & epigenetic gene silencing/of the RAS signaling pathway may play an important role in epigenetic inactivation of OPCML in human epithelial ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125875.RASHgE0q3RGyE8nuQdqntpdVOxCWOY9dnIsckZyq-uHPk130_provenance.
- NP125877.RAZNcerrLaZMUM76G99Z5iRm_NsjgQKfz3VGMjQNLawQU130_assertion description "[VEGF and HIF-1alpha expression are inhibited by SU5416 through the inhibition of PI3K/AKT/p70S6K1 pathway in ovarian cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125877.RAZNcerrLaZMUM76G99Z5iRm_NsjgQKfz3VGMjQNLawQU130_provenance.
- NP125882.RAVFfWeE0bk98iLjEUZrkwxslb3VKCq6i2bYOSYyJn3zQ130_assertion description "[overexpression of VEGF, its receptors flt-1, KDR/flk-1 and TGF-beta interaction may play an important role in the ovarian cancer biology, with potential effects on tumor growth and angiogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125882.RAVFfWeE0bk98iLjEUZrkwxslb3VKCq6i2bYOSYyJn3zQ130_provenance.
- NP125883.RAYoZ3gkJ0gnS3Rr0OpCs2xzysa5lRK--GDviR_-pxLP4130_assertion description "[Increased VEGF in ovarian cancers ascitic fluid may have an important role in its peritoneal spread and be a prognostic factor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125883.RAYoZ3gkJ0gnS3Rr0OpCs2xzysa5lRK--GDviR_-pxLP4130_provenance.
- NP125888.RAZWpiVqFJtFRXF3ymJyWCHBBxGYbWzBtsN7vMGiIh8i0130_assertion description "[Presence is ssociated with regulation of ovarian cancer cell mesothelial invasion and metastatic progression and offers the possibility of novel therapeutic targets.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125888.RAZWpiVqFJtFRXF3ymJyWCHBBxGYbWzBtsN7vMGiIh8i0130_provenance.
- NP125892.RAUHNFroPuwfMkjg8RZMCWU1ICeKe4pLn-mPEB_7ixOYY130_assertion description "[DLEC1 suppresses the growth of ovarian cancer cells and its downregulation is closely associated with promoter hypermethylation and histone hypoacetylation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125892.RAUHNFroPuwfMkjg8RZMCWU1ICeKe4pLn-mPEB_7ixOYY130_provenance.
- NP125895.RAVgqE9cHcauMa1RnTB6W_75OMB2y1wxMsnFOwI9qAwaY130_assertion description "[study showed that ovarian cancer cell lines expressiing cytoplasmic maspin are more sensitive to cisplatin and that cytoplasmic and nuclear maspin expressing ovarian carcinoma patients have longer survival rates ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125895.RAVgqE9cHcauMa1RnTB6W_75OMB2y1wxMsnFOwI9qAwaY130_provenance.
- NP125899.RAbIMHMZY1YGCBdeTWNE6_bZ_A8t_bMKUcTczwJ0TlhK4130_assertion description "[EPHA2 may have a role in progression of ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125899.RAbIMHMZY1YGCBdeTWNE6_bZ_A8t_bMKUcTczwJ0TlhK4130_provenance.
- NP125900.RAfvgO0F7ueclH5Ns6NkCgz4KksVq1YU40xZuCQaBnmEQ130_assertion description "[Suggest that ZNF217 might play a crucial role in the proliferation and invasion of ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125900.RAfvgO0F7ueclH5Ns6NkCgz4KksVq1YU40xZuCQaBnmEQ130_provenance.
- NP125901.RAZrA8oTVZWoyo0Bqd1SDidIlNbk3asxe_WH7TXO28XYc130_assertion description "[Data show that low IL-1 RA levels in ascites are associated with a significant improvement in postoperative and progression-free ovarian cancer survival, and suggest that IL-1 RA shows a prognostic relevance in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125901.RAZrA8oTVZWoyo0Bqd1SDidIlNbk3asxe_WH7TXO28XYc130_provenance.
- NP125905.RAfAJB_sNAHs6jRtxL76uOoN2eZjH9jJjaNzVzvGsWDOw130_assertion description "[In PDGFR-expressing immortalized ovarian cancer cells, PDGF strongly induced VEGF secretion, suggesting a correlation between the PDGF & VEGF networks in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125905.RAfAJB_sNAHs6jRtxL76uOoN2eZjH9jJjaNzVzvGsWDOw130_provenance.
- NP125906.RARd-o75e3VDSn4FKJioeH46uDkHloHFdNxOupvFmF0o0130_assertion description "[up-regulation of DDR1, CLDN3, and epithelial cell adhesion molecule are early events in the development of epithelial ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125906.RARd-o75e3VDSn4FKJioeH46uDkHloHFdNxOupvFmF0o0130_provenance.
- NP125907.RARetByTwA1QUxdW-f-ZBYeROKvrtWf3ELmCgyJbF6bEQ130_assertion description "[study demonstrated the existence of somatic mutations and methylation of CHD5 in primary epithelial ovarian cancers; CHD5 may play a role as a tumor suppressor gene in ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125907.RARetByTwA1QUxdW-f-ZBYeROKvrtWf3ELmCgyJbF6bEQ130_provenance.
- NP125914.RAXQlzPxiPPrrrBwJpeWm5z5URQlUyAQGOnTh-E0YVTxk130_assertion description "[Proliferation-promoting E2F transcription factor E2F-2 plays a pivotal role in the tumor biology of ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125914.RAXQlzPxiPPrrrBwJpeWm5z5URQlUyAQGOnTh-E0YVTxk130_provenance.
- NP125915.RAQ2KlnjDnkH7_or-VKJuajKkBgEFY3R3TcsQhSh3dpUQ130_assertion description "[GGT1 is a biological tumor marker for epithelial ovarian cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125915.RAQ2KlnjDnkH7_or-VKJuajKkBgEFY3R3TcsQhSh3dpUQ130_provenance.
- NP125922.RAR0T_SI1R7MmAq-BGP2S3lVbcvCDdbbFwMbhktL31APA130_assertion description "[TK1 gene expression together with TS, TP and DPD gene expression may play important roles in influencing the malignant behavior of epithelial ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125922.RAR0T_SI1R7MmAq-BGP2S3lVbcvCDdbbFwMbhktL31APA130_provenance.
- NP125925.RAdCCIpkH4tUmOgdRfSYu6ZDcMCan07Rh0iDKB-aQbBWA130_assertion description "[Loss of heterozygosity and microsatellite instability at the Xq28 and the A/G heterozygosity of the QM gene are associated with ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125925.RAdCCIpkH4tUmOgdRfSYu6ZDcMCan07Rh0iDKB-aQbBWA130_provenance.
- NP125934.RAcHg5Q5oNZ77_As9u4M0mM0EOwlv-t8iRPPTMdYfjKeA130_assertion description "[Inhibition of STAT3 reduced the motility of ovarian cancer cells in vitro, and activated STAT3 localized not only to nuclei but also to focal adhesions in these cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125934.RAcHg5Q5oNZ77_As9u4M0mM0EOwlv-t8iRPPTMdYfjKeA130_provenance.
- NP125939.RAR87x1WBgd9nA6haF3t3-XPkD5Ltyh5pD0j3SW8xUblU130_assertion description "[Expression of LPA2 during ovarian carcinogenesis contributes to ovarian cancer aggressiveness, suggesting that the targeting of LPA production and action may have potential for the treatment of ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125939.RAR87x1WBgd9nA6haF3t3-XPkD5Ltyh5pD0j3SW8xUblU130_provenance.
- NP125942.RAaIpug3_v-aodEDQS7GNUV3sm99KEaP59MjgZ8afsXm4130_assertion description "[High XRCC1 mRNA levels is associated with Clear cell tumors of epithelial ovarian cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125942.RAaIpug3_v-aodEDQS7GNUV3sm99KEaP59MjgZ8afsXm4130_provenance.
- NP125961.RAc9z3x6OmC7Lp71EnNoPWeB8VFbdeEZ5R_zBwR0cvdgM130_assertion description "[Our findings indicate that levels of Dicer and Drosha mRNA in ovarian-cancer cells have associations with outcomes in patients with ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125961.RAc9z3x6OmC7Lp71EnNoPWeB8VFbdeEZ5R_zBwR0cvdgM130_provenance.
- NP125963.RAbRrJy92rMH8JIsasMmWCtsXi2pv4SdB9kVCmiH2y0Fk130_assertion description "[Single-nucleotide polymorphisms in the CYP19A1 is associated with ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125963.RAbRrJy92rMH8JIsasMmWCtsXi2pv4SdB9kVCmiH2y0Fk130_provenance.
- NP125964.RAfwNHwbh_j5LqRMFMsP3UzYwP94nY7WUItBXvxtKtr-c130_assertion description "[CYP19 polymorphism is associated with ovarian cancer and endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125964.RAfwNHwbh_j5LqRMFMsP3UzYwP94nY7WUItBXvxtKtr-c130_provenance.