Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP127134.RAc8Hwejg3TKbbjqpafxOPWYEXoJ453tKgZCafHP9C1kE130_assertion description "[NAIP-deltaEx10-11: a novel splice variant of the apoptosis inhibitor NAIP is differently expressed in drug-sensitive and multidrug-resistant HL60 leukemia cells/transcripts might be involved in tumor resistance to chemotherapeutic agents.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127134.RAc8Hwejg3TKbbjqpafxOPWYEXoJ453tKgZCafHP9C1kE130_provenance.
- NP127135.RAU6p2CWui9d2MOmlrURLRWDb8KhjJtdKliAMtGr0nAdo130_assertion description "[Review/is translocated or mutated in various lymphomas & leukemias, forming fusion proteins or NPM mutant products/structural, functional, biological, clinical & pathological features of normal & mutant NPM1 & its malignancies are reviewed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127135.RAU6p2CWui9d2MOmlrURLRWDb8KhjJtdKliAMtGr0nAdo130_provenance.
- NP127138.RAfEANSqkhvsIG6CvrZf43W7EDLKT353d4XU557Gp75U4130_assertion description "[expression of bcr/abl hybridized gene in chronic myeloid leukemia (CML), acute lymphatic leukemia (ALL) and polycythemia vera (PV), and its clinical significance ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127138.RAfEANSqkhvsIG6CvrZf43W7EDLKT353d4XU557Gp75U4130_provenance.
- NP127140.RAY0yGgc2gTJoxNTmdJSVcplWUeYyVs9-Uhe5EZNVLBck130_assertion description "[Describe RT-PCR/capillary electrophoresis method for quantification of bcr-abl transcripts in leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127140.RAY0yGgc2gTJoxNTmdJSVcplWUeYyVs9-Uhe5EZNVLBck130_provenance.
- NP127142.RAe7trjU-b9oM08KwC1rX5049nTjV7ZsQCIY3IgKxXuMo130_assertion description "[Along with BCR, deleted in leukemia, myeloid, philadelphia-positive.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127142.RAe7trjU-b9oM08KwC1rX5049nTjV7ZsQCIY3IgKxXuMo130_provenance.
- NP127143.RAZd9BOh5FIN4NXiNdJomZnmtDNdWdQN50jbiFyXyV_58130_assertion description "[In CREB-overexpressing transfected cells, Meis1 RNA expression was 3-fold higher than in untransfected cells/AML cells, it was 5- to 10-fold higher than in the control cells/overexpression may result in leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127143.RAZd9BOh5FIN4NXiNdJomZnmtDNdWdQN50jbiFyXyV_58130_provenance.
- NP127144.RAahl16CT9NHK23hLQfudZl5p1esBZL5OvLP1SYjOcWtA130_assertion description "[survivin has a role in proliferation of leukemia cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127144.RAahl16CT9NHK23hLQfudZl5p1esBZL5OvLP1SYjOcWtA130_provenance.
- NP127147.RAZOR-RyGAqJoYOh-MK2oCL-VVVawwk0zBfA11NNt0mjg130_assertion description "[Activation of the thyroid hormone receptor beta/retinoid X receptor alpha heterodimer by T (3) stimulated expression of the hepatic leukemia factor, which increases HIF-1alpha gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127147.RAZOR-RyGAqJoYOh-MK2oCL-VVVawwk0zBfA11NNt0mjg130_provenance.
- NP127155.RAZ9gcLC00AaE5pypvg5AxRSfHrIwqPvbLwYE4HdgT7Vw130_assertion description "[promyelocytic leukemia protein (PML) and hDaxx, mediate an intrinsic immune response against HCMV infection by contributing independently to the silencing of HCMV IE gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127155.RAZ9gcLC00AaE5pypvg5AxRSfHrIwqPvbLwYE4HdgT7Vw130_provenance.
- NP127159.RARagDBa2-qomiODG-MXG3NRIUoEnCk13jndLt6Y7tqDg130_assertion description "[Promyelocytic leukemia protein PML inhibits Nur77-mediated transcription through specific functional interactions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127159.RARagDBa2-qomiODG-MXG3NRIUoEnCk13jndLt6Y7tqDg130_provenance.
- NP127160.RAVgbnQIu7qKQobc2OGA4qQSM25mfxLoE0aZDLKLCUHB4130_assertion description "[Angiopoetin-Tie2 autocrine pathway works in primary acute meylocytic leukemia cells or not by using soluble Tie2-Fc, which inhibits Angiopoietins from binding to Tie2 receptor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127160.RAVgbnQIu7qKQobc2OGA4qQSM25mfxLoE0aZDLKLCUHB4130_provenance.
- NP127161.RAXpp2_CcUACFehQ6dYrvInaGbJC1ME0TSQIz-ksIYs7U130_assertion description "[VEGF-D could contribute to leukemia and lymphoma growth via the induction of angiogenesis in bone marrow and lymphoid tissues ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127161.RAXpp2_CcUACFehQ6dYrvInaGbJC1ME0TSQIz-ksIYs7U130_provenance.
- NP127164.RAUie93-z-Nf1auyynFnPuD8nCbqZw_bFjj5qg1DXGtNY130_assertion description "[REVIEW: Role of erythropoietin receptor in myelodysplastic syndrome and leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127164.RAUie93-z-Nf1auyynFnPuD8nCbqZw_bFjj5qg1DXGtNY130_provenance.
- NP127166.RAfGsbrLYR6uMIrDU_ZdaZKYk93Q6GYZQY4VsykzuDZys130_assertion description "[No JAK2 gene mutations or deletions are associated with Philadelphia chromosome-positive leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127166.RAfGsbrLYR6uMIrDU_ZdaZKYk93Q6GYZQY4VsykzuDZys130_provenance.
- NP127167.RAblV_Drd_pUZbbflqEh2ZmrpBtdZR93I3YLTz5MyU9Ss130_assertion description "[JAK2 V617F mutations in CBF leukemias have a role in disease progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127167.RAblV_Drd_pUZbbflqEh2ZmrpBtdZR93I3YLTz5MyU9Ss130_provenance.
- NP127170.RAW0R4CkuLWo17aDHTAyWzhr7v-QKb4T4S-kQUw3THEAk130_assertion description "[data reveal new properties for the leucine zipper domain and thus might provide new clues to understanding the mechanisms by which AF10 fusion proteins in which the PHD domain is lost might trigger leukemias in humans ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127170.RAW0R4CkuLWo17aDHTAyWzhr7v-QKb4T4S-kQUw3THEAk130_provenance.
- NP127189.RAZdm5N9qBHMCMCpQ4IaGUUooVNNwfARoCtJRID9JtRhw130_assertion description "[Expression of p53 and bcl-2 proteins in acute leukemias: an immunocytochemical study ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127189.RAZdm5N9qBHMCMCpQ4IaGUUooVNNwfARoCtJRID9JtRhw130_provenance.
- NP127190.RAc37EjVQR3hvUeUDozGkzxaBvelcpqOMh3tHCPqLZ1sQ130_assertion description "[Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127190.RAc37EjVQR3hvUeUDozGkzxaBvelcpqOMh3tHCPqLZ1sQ130_provenance.
- NP127192.RAcbWkAX8dC6iKM80qbdPjVX02UNIrMaG4KIX3K4bdhKU130_assertion description "[expression of hBex1 in leukemic cells is a novel mechanism by which chemoresistance is achieved and suggests that hBex1 is a potential molecular target for the development of novel leukemia treatments ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127192.RAcbWkAX8dC6iKM80qbdPjVX02UNIrMaG4KIX3K4bdhKU130_provenance.
- NP127193.RAbtFFOxlOGV0feaZ8OLDa_HdSWtOlzheXXqsFhSwexoI130_assertion description "[immaturity of NK cells and inhibitory effect of NKG2A override graft versus leukemia effect ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127193.RAbtFFOxlOGV0feaZ8OLDa_HdSWtOlzheXXqsFhSwexoI130_provenance.
- NP127194.RAf0-Rf5wA4EAEeCQfa5UYhc3qKyg2gN_X_AEbOyP0FyQ130_assertion description "[Nox1 partially restores the defective oxidases of gp91phox-deficient PLB-985 leukemia cells and peripheral blood stem cells of X-linked chronic granulomatous disease patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127194.RAf0-Rf5wA4EAEeCQfa5UYhc3qKyg2gN_X_AEbOyP0FyQ130_provenance.
- NP127195.RATqdee3yHtdipfBJZ5UXkqBFEDyUz_1stg5kIb9u31ek130_assertion description "[lipocalin 2 has at least two functions related to tumorigenesis, one involving apoptosis induction of normal hematopoietic cells and the other being tissue invasion by leukemia cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127195.RATqdee3yHtdipfBJZ5UXkqBFEDyUz_1stg5kIb9u31ek130_provenance.
- NP127208.RAVsXvt8x5k8oTelyE9GunEW1_VpTg6T0mkO-ZIr7z_pI130_assertion description "[During the G1-to-S phase transition, HCF-1 recruits the mixed-lineage leukemia (MLL) and Set-1 histone H3 lysine 4 methyltransferases to E2F-responsive promoters and induces histone methylation and transcriptional activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127208.RAVsXvt8x5k8oTelyE9GunEW1_VpTg6T0mkO-ZIr7z_pI130_provenance.
- NP127209.RAYC8pNMYveHGfdZtK1h2_kcKEG4SNa7_u9FB9cwucvmw130_assertion description "[expression of NM23-H (1) gene in acute leukemia (AL) and evaluate the relationship between NM23-H (1) expression and clinical features ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127209.RAYC8pNMYveHGfdZtK1h2_kcKEG4SNa7_u9FB9cwucvmw130_provenance.
- NP127212.RAZVr9aNOopc13sQVZBSAK_Jsjqnfxi-s3S3z9OvCOFWY130_assertion description "[REVIEW: Congenital neutropenia patients with acquired CSF3R mutations define a group with high risk for development of leukemia; discussion of possible pathomechanism ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127212.RAZVr9aNOopc13sQVZBSAK_Jsjqnfxi-s3S3z9OvCOFWY130_provenance.
- NP127214.RAf2vXveYBoI-4sgaiIcGigrWBTnYxdutw_rJyW-bPaeA130_assertion description "[Data suggest that FEZ1 has an important centrosomal function and supply new mechanistic insights to the formation of flower-like nuclei, which are a phenotypical hallmark of human leukemia cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127214.RAf2vXveYBoI-4sgaiIcGigrWBTnYxdutw_rJyW-bPaeA130_provenance.
- NP127222.RAR_pFhORm5icB5LpgaAHlVmSYKULuAH50hcR6TMT2Vx0130_assertion description "[Drug-resistant and drug-sensitive acute leukemia patients were compared for single nucleotide polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127222.RAR_pFhORm5icB5LpgaAHlVmSYKULuAH50hcR6TMT2Vx0130_provenance.
- NP127223.RAa2pFjweRhd79N6Y0_A6PrHHenOWxITxKSro5cT78zGg130_assertion description "[MDR1 expression affects complete remission and survival rates in acute leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127223.RAa2pFjweRhd79N6Y0_A6PrHHenOWxITxKSro5cT78zGg130_provenance.
- NP127234.RAatg5OtSH0TYQEGRY1Sb7D6jYXVecsSH3dAAoKDx6ijo130_assertion description "[Amplification of this gene in childhood acute lymphoblsatic leukemia is associatd with poor outcome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127234.RAatg5OtSH0TYQEGRY1Sb7D6jYXVecsSH3dAAoKDx6ijo130_provenance.
- NP127237.RAZIjyqHy-ubffpKvrwDGIz4b2oQ8r588qbf2OOLySYbY130_assertion description "[The potentially functional genetic polymorphism 454CA of the JWA gene appears to contribute to the risk of multiple kinds of leukemia in a south Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127237.RAZIjyqHy-ubffpKvrwDGIz4b2oQ8r588qbf2OOLySYbY130_provenance.
- NP127238.RAWzcXG-G-0s5LpGqeM4heJx-2zN8jnTlMqHHBh_qSmMc130_assertion description "[Transcriptional repression of the p15 gene by dna methylation is associated with adult acute leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127238.RAWzcXG-G-0s5LpGqeM4heJx-2zN8jnTlMqHHBh_qSmMc130_provenance.
- NP127240.RATPER_SUNrpzoBvXvkzP3mJGoF11hYx1DNwDXb9TkZCk130_assertion description "[Data show that caspase-3 antisense oligodeoxynucleotides inhibit apoptosis in gamma-irradiated human leukemia HL-60 cells.(]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127240.RATPER_SUNrpzoBvXvkzP3mJGoF11hYx1DNwDXb9TkZCk130_provenance.
- NP127241.RAVPi5otZOWf-xutNsRN9yytYKvEf5Mv7cnhs2CVE-GMc130_assertion description "[These findings suggest a role for ANKHD1 as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127241.RAVPi5otZOWf-xutNsRN9yytYKvEf5Mv7cnhs2CVE-GMc130_provenance.
- NP127243.RAV_zbhEe6fKXhsktGTFe-0okK0S0gDuqgbq4BB5nkIHs130_assertion description "[characterization of the TCF4 with microsatellite instability (MSI) in colon cancer and leukemia cell lines; results delineate a novel role for MSI+TCF4 in leukemia and colon cancer progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127243.RAV_zbhEe6fKXhsktGTFe-0okK0S0gDuqgbq4BB5nkIHs130_provenance.
- NP127245.RAftS7JxPVU9RhmtLlGsJrVT5BQmucACkmhKK-XT9Esrg130_assertion description "[concetration in children with acute lymphoblbastic leukemia after chemotherapy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127245.RAftS7JxPVU9RhmtLlGsJrVT5BQmucACkmhKK-XT9Esrg130_provenance.
- NP127250.RAeQLs-NIcQtCDSpXtawEBWl3P3VDPXabV1V4_CbiR2iE130_assertion description "[Data demonstrate that PML (promyelocytic leukemia) interacts with Chk2 and activates Chk2 by mediating its autophosphorylation step.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127250.RAeQLs-NIcQtCDSpXtawEBWl3P3VDPXabV1V4_CbiR2iE130_provenance.
- NP127254.RATqFJA_WFxox6y-CYF94alcpIw2VIfXgGfjTu5ll0bdQ130_assertion description "[analysis of a rare MLL-AF4 (MLL-AFF1) fusion rearrangement in infant leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127254.RATqFJA_WFxox6y-CYF94alcpIw2VIfXgGfjTu5ll0bdQ130_provenance.
- NP127255.RAcNJTwJig07fn5WD5G6XbVG7JWfxPVTT94BuhpHrio-4130_assertion description "[the cell cycle control exerted by MLL-AF4 may be responsible of resistance to cell-death promoting stimuli in leukemia carrying the t (4; 11) translocation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127255.RAcNJTwJig07fn5WD5G6XbVG7JWfxPVTT94BuhpHrio-4130_provenance.
- NP127256.RAfjF-USy-PAzuDunuzvTTunVWa2IbvFBrbN3y86KIg3c130_assertion description "[analysis of a rare MLL-AF4 (MLL-AFF1) fusion rearrangement in infant leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127256.RAfjF-USy-PAzuDunuzvTTunVWa2IbvFBrbN3y86KIg3c130_provenance.
- NP127259.RASQLK4adEvQ2zk7KRBdgxg40UuYtRx1Uonyo9-l6PSHE130_assertion description "[review considers recent advances in understanding of the role of MLL gene rearrangements in pediatric leukemia [review]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127259.RASQLK4adEvQ2zk7KRBdgxg40UuYtRx1Uonyo9-l6PSHE130_provenance.
- NP127260.RAQu-liN3wTshhwSm3JsK1sDyeSyjfHpi7RfhKSMNGPrg130_assertion description "[In acute myeloid leukemia with mixed lineage leukemia partial tandem duplication, the SLC5A8 tumor suppressor gene promoter was more frequently hypermethylated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127260.RAQu-liN3wTshhwSm3JsK1sDyeSyjfHpi7RfhKSMNGPrg130_provenance.
- NP127263.RAb8w2825XJId7m1_YDyWCAexIwhrQyJUUmM8-finBu-w130_assertion description "[interactions between DNA repair genes hMLH1, APEX1, MGMT, XRCC1 and XPD and electric transformers and power line distances from the houses of childhood acute leukemia patients revealed gene-environment interaction existed with XRCC1 Ex9+16 A allele ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127263.RAb8w2825XJId7m1_YDyWCAexIwhrQyJUUmM8-finBu-w130_provenance.
- NP127265.RAZ79hQb89wwUAWK87-9QNChX-xLErkftLEl7hACTe4lI130_assertion description "[candidate tumor suppressor genes PARK2 and PACRG are epigenetically regulated in human leukemia, suggesting that abnormal methylation and regulation of PARK2 and PACRG may play a role in the pathogenesis and development of this hematological neoplasm ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127265.RAZ79hQb89wwUAWK87-9QNChX-xLErkftLEl7hACTe4lI130_provenance.
- NP127267.RAXhiYp3q5qCalE6OLW8oq0au5kVDfBXXAcEs88VIu3W8130_assertion description "[studies link menin with the MLL histone methyltransferase machinery, with implications for Hox gene expression in leukemia pathogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127267.RAXhiYp3q5qCalE6OLW8oq0au5kVDfBXXAcEs88VIu3W8130_provenance.
- NP127268.RAbnyp0guBkhenq_naCTncB3DHuDgmfWEzg0xlwdhVQC0130_assertion description "[identified 6 children in 5 kindreds exhibiting the co-occurrence of BRCA2 mutations, FA, and early onset acute leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127268.RAbnyp0guBkhenq_naCTncB3DHuDgmfWEzg0xlwdhVQC0130_provenance.
- NP127277.RAYAL7FJDsU5KhIxp_KBUs4d2lI51okGVa9TX_M5PCkx0130_assertion description "[compared BCR-ABL transcript type and level with kinase domain (KD) mutation status, genotype, and phenotype in 1855 Ph (+) leukemias ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127277.RAYAL7FJDsU5KhIxp_KBUs4d2lI51okGVa9TX_M5PCkx0130_provenance.
- NP127280.RAXOcthyA2S1rvOuzTODIDYCIDyQ0yfbzZTj-s6kcOkhk130_assertion description "[renin expression observed in leukemia cells disappeared with remission induction, but did not disappear with induction of cell differentiation in vivo, indicating that renin expression is associated with a blastic phenotype rather than cell proliferation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127280.RAXOcthyA2S1rvOuzTODIDYCIDyQ0yfbzZTj-s6kcOkhk130_provenance.
- NP127281.RAXuii-31JADe8pOpQbPyCfNtIqhSQ7Ubkadk5YhEgCTg130_assertion description "[in contrast to results for ACE blood and bone marrow levels in leukemia patients, renin levels did not vary significantly between bone marrow and peripheral blood.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127281.RAXuii-31JADe8pOpQbPyCfNtIqhSQ7Ubkadk5YhEgCTg130_provenance.
- NP127285.RAXdfRixO2cUBtJ_kWAFkE50-m5_tGR9CTSIs_FKHp-Lg130_assertion description "[Id1 is an important target of constitutively activated tyrosine kinases and may be a therapeutic target for leukemias associated with oncogenic tyrosine kinases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127285.RAXdfRixO2cUBtJ_kWAFkE50-m5_tGR9CTSIs_FKHp-Lg130_provenance.
- NP127294.RAcSzEUnmxefCBDZ8FixSCvgFRe1SoF4PsalCccMfKj2s130_assertion description "[The data indicate an increase in the expression and total activity of endogenous p60 (c-Src) in several GM-CSF-independent 1 cultured leukemia cell mutants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127294.RAcSzEUnmxefCBDZ8FixSCvgFRe1SoF4PsalCccMfKj2s130_provenance.
- NP127296.RAZIWKvzxB-hxLpD038os5upFdRRshyOQHApUwV8Pm7HM130_assertion description "[These data provide an explanation for apoptosome inhibition by activated leukemogenic tyrosine kinases and suggest that alterations in Hsp90beta-apoptosome interactions may contribute to chemoresistance in leukemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127296.RAZIWKvzxB-hxLpD038os5upFdRRshyOQHApUwV8Pm7HM130_provenance.
- NP127297.RASPaXeVwrFrJDouCYmt1XW9XCUK-aityYmPjSADW51SE130_assertion description "[These findings suggest that downregulating CIAPIN1 could sensitize leukemia cells to chemotherapeutic drugs by downregulating MDR-1 and Bcl-2 and by upregulating Bax.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127297.RASPaXeVwrFrJDouCYmt1XW9XCUK-aityYmPjSADW51SE130_provenance.
- NP127301.RAXz9at26H9XIhSVwtznBVgKE5nrruzM_2ZLeQ0hLPxH0130_assertion description "[Expression of a CALM-AF10 fusion gene leads to Hoxa cluster overexpression and acute leukemia in transgenic mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127301.RAXz9at26H9XIhSVwtznBVgKE5nrruzM_2ZLeQ0hLPxH0130_provenance.
- NP127314.RAYMiygfkmYPAPHNNC8FDhxJO4YTlyntK0lcll2WmroqA130_assertion description "[Cytotoxic T lymphocytes display strong cytotoxic activity against leukemia cells expressing WT1 endogenously but not against WT1 (-) human tumor cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127314.RAYMiygfkmYPAPHNNC8FDhxJO4YTlyntK0lcll2WmroqA130_provenance.
- NP127321.RAeedJZZMpavP2cztobsaMO8swpYWVk4f4YsAHFUlN158130_assertion description "[in leukemia patients, the ACE concentration was found to be significantly higher in the bone marrow than in the peripheral blood, with level correlated with blast percentages, indicating presence of a local BM renin angiotensin system ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127321.RAeedJZZMpavP2cztobsaMO8swpYWVk4f4YsAHFUlN158130_provenance.
- NP127327.RAdu6Q1LbExT8wB0ORTo0dK32rXKiNa1ci5wD8-OQsdZo130_assertion description "[REVIEW: Association of expression of VEGF and receptors in human leukemia and lymphoma, resulting in the generation of autocrine loops that may support cancer cell survival and proliferation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127327.RAdu6Q1LbExT8wB0ORTo0dK32rXKiNa1ci5wD8-OQsdZo130_provenance.
- NP127329.RAR6OGB3ZY5qfax8iN4ruCeabcixXHysctS7Yq0dhCdE0130_assertion description "[Leukemia patients showing parallel activation of the studied proteins trended to exhibit higher incidence of fatal outcome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127329.RAR6OGB3ZY5qfax8iN4ruCeabcixXHysctS7Yq0dhCdE0130_provenance.
- NP127340.RAQDG_tdlmCLUcoXwQeQXwSpZ1T_oPjV3hPK5_Wa70-V8130_assertion description "[The expression of mRNA for MDR1 and LRP was determined in bone marrow samples from control, de novo acute myelocytic leukemia, myelodysplastic syndrome (MDS), MDS at the time of overt leukemia (OL) transformation (MDS -- > OL), and after transformation (OL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127340.RAQDG_tdlmCLUcoXwQeQXwSpZ1T_oPjV3hPK5_Wa70-V8130_provenance.
- NP127344.RAfFFDCK9DFAJyNr--At7EwyzkDNpvdCfMwxCAL0u2Ebo130_assertion description "[aberrant methylation of p16 and EDNRB was highly prevalent in leukemia patients in Taiwan.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127344.RAfFFDCK9DFAJyNr--At7EwyzkDNpvdCfMwxCAL0u2Ebo130_provenance.
- NP127351.RAZ6X7SuhkQve0-CdNQzTSftvsfLPPaVnyl7B58JcZXvA130_assertion description "[In addition to SOCS3 expression, IL-10 induces SOCS1 up-regulation in all cell lines tested, including murine Ba/F3 pro-B cells, MC/9 mast cells, M1 leukemia cells, U3A human fibroblasts, and primary mouse CD+ T cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127351.RAZ6X7SuhkQve0-CdNQzTSftvsfLPPaVnyl7B58JcZXvA130_provenance.
- NP127353.RAXqBFS2wQQWidfS9XPLdAZxMlSmnrd9SfprCdBPNMwIU130_assertion description "[Proliferating NK cells were simultaneously positive for CXCR1 in all aggressive NK cell leukemia patients examined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127353.RAXqBFS2wQQWidfS9XPLdAZxMlSmnrd9SfprCdBPNMwIU130_provenance.
- NP127354.RAZe36Xc_srlftFy41CfbBfEM2H0NZJsbgfRb7gCEZMco130_assertion description "[Genetic variants of IL4 could contribute to the development of chronic disseminated candidiasis in adult patients with acute leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127354.RAZe36Xc_srlftFy41CfbBfEM2H0NZJsbgfRb7gCEZMco130_provenance.
- NP127359.RAcuLySMh9QKyPBT1qLBwMMK0HoQp7svsamYCuXIT5dcA130_assertion description "[The results from this study reveal that cannabidiol, acting through CB2 and regulation of Nox4 and p22 (phox) expression, may be a novel and highly selective treatment for leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127359.RAcuLySMh9QKyPBT1qLBwMMK0HoQp7svsamYCuXIT5dcA130_provenance.
- NP127361.RAZyRTPugFv7DsGKscr5_c4s6vI-eIBhQWMPXQlKpGdQk130_assertion description "[During the G1-to-S phase transition, HCF-1 recruits the mixed-lineage leukemia (MLL) and Set-1 histone H3 lysine 4 methyltransferases to E2F-responsive promoters and induces histone methylation and transcriptional activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127361.RAZyRTPugFv7DsGKscr5_c4s6vI-eIBhQWMPXQlKpGdQk130_provenance.
- NP127364.RASyLLIXdb6TZWULNiPC4cjchhanpv3Q6JeV4hkKrGQZY130_assertion description "[Data demonstrate that the Drosophila homologs of mixed-lineage leukemia protein and host cell factor 1, called Trithorax and dHCF, are both cleaved by Drosophila taspase 1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127364.RASyLLIXdb6TZWULNiPC4cjchhanpv3Q6JeV4hkKrGQZY130_provenance.
- NP127366.RAYiEhLV0bStwrK7pVqOxUjK8b1QhW-VUFjNDFPBBeCB4130_assertion description "[The correlation between infant leukemia and in utero exposure to topoisomerase II (topo-II) inhibitor has been clarified.in vitro effect of etoposide on cleavage of the MLL gene in cord and peripheral blood mononuclear cells (MNCs).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127366.RAYiEhLV0bStwrK7pVqOxUjK8b1QhW-VUFjNDFPBBeCB4130_provenance.
- NP127370.RAV1oL5nNSUc9QBJT8nHcWZxKVcFy1UrnbZztGbN2Lj-s130_assertion description "[GATA1 mutations in Down syndrome and its altered role in DS and myeloid leukemia may lead to an increased understanding of why children with DS are markedly predisposed to leukemia.(review) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127370.RAV1oL5nNSUc9QBJT8nHcWZxKVcFy1UrnbZztGbN2Lj-s130_provenance.
- NP127371.RAXKN-caS1PxJnpv20I7CEc34ovWOCedI-DizoRqOep-8130_assertion description "[Overexpression of PRAME was associated with childhood acute leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127371.RAXKN-caS1PxJnpv20I7CEc34ovWOCedI-DizoRqOep-8130_provenance.
- NP127377.RAaHIpnaXdkCPdI3n5-OqMAfMq_ikjEE-8MN9FmpSklQ0130_assertion description "[Overexpression of mdm2 was seen predominantly in blastoid mantle cell leukemia, seemed unrelated to gain of chromosome 12, did not reflect a high proliferative rate, but might indicate an alternative mechanism of inactivating p53.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127377.RAaHIpnaXdkCPdI3n5-OqMAfMq_ikjEE-8MN9FmpSklQ0130_provenance.
- NP127380.RAVjl9nrEN61GwDyZcHQc9OmRya7SpwsKirrnePPhLLKI130_assertion description "[sorcin plays an important role in the emergence of MDR in leukemia cells via regulating cell apoptosis pathways ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127380.RAVjl9nrEN61GwDyZcHQc9OmRya7SpwsKirrnePPhLLKI130_provenance.
- NP127391.RAfiy56tuDovpNmNqdoFK1j2g2fWKsQE6McSHVvhAqPEY130_assertion description "[Results suggest that the sumoylated COOH terminus of EAAT2 associates with the promyelocytic leukemia nuclear bodies in hSod1 mutatnt transgenic mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127391.RAfiy56tuDovpNmNqdoFK1j2g2fWKsQE6McSHVvhAqPEY130_provenance.
- NP127409.RAWKPEI83_nqhMdcyUHj4glOXharwOc_MypSQwbmQ_aMs130_assertion description "[it is suggested that a high level of GCS in leukemia is possible contributed to multidrug resistance of leukemia cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127409.RAWKPEI83_nqhMdcyUHj4glOXharwOc_MypSQwbmQ_aMs130_provenance.
- NP127414.RAZWRlNaRsymiY95tSTC_QuCp8xSwES-AWDYg60Mcoew0130_assertion description "[The lower Cyclin A gene expression would predict drug resistance for acute leukemia patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127414.RAZWRlNaRsymiY95tSTC_QuCp8xSwES-AWDYg60Mcoew0130_provenance.
- NP127415.RATrMUp2aFuX3WQxV7lgcua-lKYCV1b85e3DDPfVqZVA0130_assertion description "[Data describe ZNF451, a nuclear protein that can be associated with promyelocytic leukemia bodies, and exerts its effects via SUMO modification machinery and trafficking of transcription regulators between promyelocytic leukemia bodies and nucleoplasm.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127415.RATrMUp2aFuX3WQxV7lgcua-lKYCV1b85e3DDPfVqZVA0130_provenance.
- NP127420.RAc3PvhSPRDVX3YvRfAIatgH4k4QcKPyLJgiwwWRS6yMU130_assertion description "[In acute leukemias with a t (11: 19) translocation, 50% of the analyzed breakpoints were within the MLLT1 gene introns/MLL gene was fused to the intact MLLT1 gene by transcriptional readthrough & a splice event, or by trans-splicing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127420.RAc3PvhSPRDVX3YvRfAIatgH4k4QcKPyLJgiwwWRS6yMU130_provenance.
- NP127424.RARV13vMN2_EeN_cAnGcgp4okuFrueiA-uEr9LPGkxicg130_assertion description "[DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127424.RARV13vMN2_EeN_cAnGcgp4okuFrueiA-uEr9LPGkxicg130_provenance.
- NP127425.RAezV-EulhPFzyDqhcmkgBMrzTlyhbgpG4E_8F4adeFOU130_assertion description "[No evidence was found for STAT5b rearrangement at the chromosomal or molecular levels in primary leukemias/activation is probably a secondary event in most leukemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127425.RAezV-EulhPFzyDqhcmkgBMrzTlyhbgpG4E_8F4adeFOU130_provenance.
- NP127431.RAdUAgL9yr057tBW4WF4MtLtYQ_XbI0hh0Hx9J8i6kPrA130_assertion description "[In addition, B cell lymphoma leukemia (Bcl) -x (L), an antiapoptotic regulator, was also highly expressed in macrophages from smokers compared with nonsmokers and subjects with asthma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127431.RAdUAgL9yr057tBW4WF4MtLtYQ_XbI0hh0Hx9J8i6kPrA130_provenance.
- NP127432.RAYRgZoBbMDYtc2FoHOAXXZzB-Ltj681mxoupkZhuqLkg130_assertion description "[These findings suggest that downregulating CIAPIN1 could sensitize leukemia cells to chemotherapeutic drugs by downregulating MDR-1 and Bcl-2 and by upregulating Bax.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127432.RAYRgZoBbMDYtc2FoHOAXXZzB-Ltj681mxoupkZhuqLkg130_provenance.
- NP127433.RATN6V7bYUiQqsAEMQ_zOzA0HBVemvE4TsFDrhpOZ5z6Q130_assertion description "[bcl-2 protein positivity did not affect significantly the AgNOR distribution either in p53 protein positive or p53-negative cases of leukemia patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127433.RATN6V7bYUiQqsAEMQ_zOzA0HBVemvE4TsFDrhpOZ5z6Q130_provenance.
- NP127434.RAefj6sglOIUKK1aExmLoETf8hBfK2rAD40oY3YByewX0130_assertion description "[Chemotherapy induced Bcl-2 cleavage was blunted by inhibition of caspase activity in leukemia cells; however, coculture with bone marrow stromal cells resulted in reduced levels of 23 kDa Bcl-2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127434.RAefj6sglOIUKK1aExmLoETf8hBfK2rAD40oY3YByewX0130_provenance.
- NP127439.RAeKbb7vUQZ9hkFlzJGIXYk99Gle-j1OSl8niJbb9aLMU130_assertion description "[results show overexpression of RAF-1 in mantle cell leukemia compared with tonsilar B-lymphocytes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127439.RAeKbb7vUQZ9hkFlzJGIXYk99Gle-j1OSl8niJbb9aLMU130_provenance.
- NP127456.RAYaBdWTlFNkbcn4BA_P4_DNve03-vaRyXSNZ6hwAzYBE130_assertion description "[Dimethylsulfoxide induced upregulation of PTEN in HL-60 leukemia cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127456.RAYaBdWTlFNkbcn4BA_P4_DNve03-vaRyXSNZ6hwAzYBE130_provenance.
- NP127468.RAT1_GnjLzRCViU34ImOM4Q46tdcaLX4evsuEfnUWhnY4130_assertion description "[FLT3 is a therapeutic target and inhibition of FLT3 tyrosine kinase activity may provide a new approach in the treatment of leukemia carrying these mutations.(review) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127468.RAT1_GnjLzRCViU34ImOM4Q46tdcaLX4evsuEfnUWhnY4130_provenance.
- NP127470.RAeyvzT-wAoHOv7Nxq0nkAs1cz4f_GxsDMA8MxCEonGvc130_assertion description "[In the present quite limited series, FLT3 mutations do not seem to have a major impact on global gene expression pattern in childhood acute leukemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127470.RAeyvzT-wAoHOv7Nxq0nkAs1cz4f_GxsDMA8MxCEonGvc130_provenance.
- NP127472.RAVwOBvJr_gbBxH6jxgihHiruqbEKC3BHCg5HG189XtNU130_assertion description "[FLT-3 is primarily expressed by hematopoietic cells & plays an important role in hematopoiesis/is also expressed in the majority of acute leukemias, in which the presence of FLT-3 activating mutations is associated with poor prognosis [review]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127472.RAVwOBvJr_gbBxH6jxgihHiruqbEKC3BHCg5HG189XtNU130_provenance.
- NP127473.RAX6hignK-7kVso00u7PzQ-o8fqQjF5OgtDZ8HDilg6c8130_assertion description "[FLT-1 targeting on subsets of acute leukemias may delay the onset of extramedullary disease, which may be advantageous in combinatorial therapeutic settings.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127473.RAX6hignK-7kVso00u7PzQ-o8fqQjF5OgtDZ8HDilg6c8130_provenance.
- NP127474.RATWuMFJl_cpYQOurY-eskIg-wPP9z7VuQsJ-7INQR7y4130_assertion description "[Involved in the pathogenesis of mature leukemias and lymphomas: mature T-cell leukemia and chronic lymphocytic leukemia (review) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127474.RATWuMFJl_cpYQOurY-eskIg-wPP9z7VuQsJ-7INQR7y4130_provenance.
- NP127476.RASTCrSOr32QKabw5xf1q3MKmYnRxG3gj07H_Dqee1dHo130_assertion description "[AbetaPP and the AIDA-1 proteins interact in vitro, in living cells and, endogenously, in leukemia cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127476.RASTCrSOr32QKabw5xf1q3MKmYnRxG3gj07H_Dqee1dHo130_provenance.
- NP127478.RAQSuFbp_DK8_QyW1EvR8xpbkJ-dbXAp-EZxRhjGO_VSI130_assertion description "[Fluorescence in situ hybridization analysis localized the Sirt7 gene to chromosome 17q25.3; a region which is frequently affected by chromosomal alterations in acute leukemias and lymphomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127478.RAQSuFbp_DK8_QyW1EvR8xpbkJ-dbXAp-EZxRhjGO_VSI130_provenance.
- NP127482.RAeJXshitIxW-EnFv9ey8MqIuoyJ1BSdHcAIcXFJnufQ8130_assertion description "[Direct interactions between the Cajal body (CB) protein coilin and the promyelocytic leukemia (PML) body protein PIASy have a role in mediating association of CBs to PML bodies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127482.RAeJXshitIxW-EnFv9ey8MqIuoyJ1BSdHcAIcXFJnufQ8130_provenance.
- NP127489.RAWpau71h-witO0TDQxh92y_vhRHZImJ1uBQos9RPdSco130_assertion description "[Activation of the thyroid hormone receptor beta/retinoid X receptor alpha heterodimer by T (3) stimulated expression of the hepatic leukemia factor, which increases HIF-1alpha gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127489.RAWpau71h-witO0TDQxh92y_vhRHZImJ1uBQos9RPdSco130_provenance.
- NP127493.RAVQfhTSGFNbg-HxU6tdHkuFYWRI39QVOCjCbcRLLDD2M130_assertion description "[data indicate an unrecognized role for the NOD2/CARD15 gene in unrelated donor hematopoietic stem cell transplantation for acute leukemia; increased risk of disease relapse suggests the wild-type gene product may contribute to graft-versus-leukemia effect ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127493.RAVQfhTSGFNbg-HxU6tdHkuFYWRI39QVOCjCbcRLLDD2M130_provenance.
- NP127496.RARwTVUNlVm5Wh75mMLorZcGCbSbPZoG-bihvT5MUkbMo130_assertion description "[Our study suggests that KIT activating mutations in AML with t (8; 21) are associated with diminished CD 19 and positive CD56 expression on leukemic blasts and, thus, can be phenotypically distinguished from AML1-ETO leukemias ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127496.RARwTVUNlVm5Wh75mMLorZcGCbSbPZoG-bihvT5MUkbMo130_provenance.
- NP127497.RAbAt_O17Pq_QikKuhxDcBTatkv2k0Zg4z7I9VGQcPPNQ130_assertion description "[Point mutations in c-Kit in core binding factor leukemias correlate with white blood cell count and the white blood cell index ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127497.RAbAt_O17Pq_QikKuhxDcBTatkv2k0Zg4z7I9VGQcPPNQ130_provenance.
- NP127502.RAYa7k0zv20SZzXyLr5oBx0pvvixtgx_Jl35j0Dal4amc130_assertion description "[Transcription levels of the MYCN gene in blood cell subpopulations of Patients with leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127502.RAYa7k0zv20SZzXyLr5oBx0pvvixtgx_Jl35j0Dal4amc130_provenance.
- NP127504.RASjke-UugpBuGxdkOrb0xsGoiLVXtIDRk9y2MMOIbGNc130_assertion description "[KIR3DL1 allotypes contribute to development of an inhibitory response to HLA-Bw4 ligands in transduced natural killer (NK) leukemia cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127504.RASjke-UugpBuGxdkOrb0xsGoiLVXtIDRk9y2MMOIbGNc130_provenance.
- NP127516.RAXpN2u1AOQ5sRZUYMyM994WqRsyHpLWHBUbEmhZkRSBk130_assertion description "[Promyelocytic leukemia protein (PML) functions as a glucocorticoid receptor co-activator by sequestering Daxx to the PML oncogenic domains (PODs) to enhance its transactivation potential.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127516.RAXpN2u1AOQ5sRZUYMyM994WqRsyHpLWHBUbEmhZkRSBk130_provenance.
- NP127519.RAUZ0fwxGj4kvT0xfSMqgFPV2E0GUOfBvrw_WuwzrZPM0130_assertion description "[ETV6/RUNX1 leads to EPOR up-regulation and that activation by EPO might be of relevance to the biology of ETV6/RUNX1-positive acute lymphoblastic leukemias ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127519.RAUZ0fwxGj4kvT0xfSMqgFPV2E0GUOfBvrw_WuwzrZPM0130_provenance.
- NP127524.RAY9uomxQSu8C1QivdoTAZ5MYAhSpIQzrLhLB3snUYOg8130_assertion description "[TEL-AML1 fusion in transgenic zebrafish induces a B cell differentiation arrest and demonstrates leukemia development associated with loss of TEL expression and elevated Bcl2/Bax ratio.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127524.RAY9uomxQSu8C1QivdoTAZ5MYAhSpIQzrLhLB3snUYOg8130_provenance.