Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP127530.RARdlYbo3wrqCsqpK-f6JTIuKgjlEFPiUlQr_y-td2sFI130_assertion description "[The level of CDD mRNA expression varies at the different stage of acute leukemia/expression level of CDD seems not to be a prognostic factor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127530.RARdlYbo3wrqCsqpK-f6JTIuKgjlEFPiUlQr_y-td2sFI130_provenance.
- NP127533.RAeHmb2HKSKiZB4CxN0IAAm1M-ZFbQjHHY_Mb6POR_ngo130_assertion description "[REVIEW: Association of expression of bFGF with clinical characteristics in human leukemia and lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127533.RAeHmb2HKSKiZB4CxN0IAAm1M-ZFbQjHHY_Mb6POR_ngo130_provenance.
- NP127538.RARs5G19NbZWWqj4XEKZXsG3pOD8Svne37DKhaI7iKlmU130_assertion description "[REVIEW: Characteristics of the C282Y mutation in childhood ALL, in contrast to other cancers, is male-specific, lacks a gene-dosage effect, and exhibits associations suggesting the involvement of another HLA-linked gene in leukemia susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127538.RARs5G19NbZWWqj4XEKZXsG3pOD8Svne37DKhaI7iKlmU130_provenance.
- NP127541.RAaPYRC4i2SI7IFBwUCd8EhplxlM2RStWPVXi1V9b-rsA130_assertion description "[TRIM5alpha, potently restricted infection by N-tropic murine leukemia virus (N-MLV) and moderately restricted human immunodeficiency virus type 1 (HIV-1) infection ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127541.RAaPYRC4i2SI7IFBwUCd8EhplxlM2RStWPVXi1V9b-rsA130_provenance.
- NP127544.RAZhjzMQHju9WvjgjdHdFgaji13xAa5V3YMEodmH45TY8130_assertion description "[demonstrate using RNAi that Stat3 activation is necessary in the invasive phenotype of trophoblast cells and can be controlled via Leukemia Inhibitory Factor (LIF) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127544.RAZhjzMQHju9WvjgjdHdFgaji13xAa5V3YMEodmH45TY8130_provenance.
- NP127547.RAZIxIdMGBldjXzqWH50Wu43eRC3bYJSrnuQk9dnQRfcY130_assertion description "[Targeted-E2A-PBX1 inhibition leads to reduced expression of the EB-1 and Wnt16b genes; aberrant expression of these genes may be a key step in leukemogenesis in t (1; 19) -positive pre-B leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127547.RAZIxIdMGBldjXzqWH50Wu43eRC3bYJSrnuQk9dnQRfcY130_provenance.
- NP127549.RAb6_lozq2CTalRMtI7PBUjAjZ2bMDK-8hHDV7lsOzGDU130_assertion description "[SENP1 restored the promyelocytic leukemia protein mediated suppression of STAT3 activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127549.RAb6_lozq2CTalRMtI7PBUjAjZ2bMDK-8hHDV7lsOzGDU130_provenance.
- NP127555.RAcDR0sU2VwlmqeTwJepyzySG4KQGVBAGCvaVGGUdsgDQ130_assertion description "[a complex interplay between Ets/Id family members and c-Myc that may be an important determinant of the diversity of telomerase activity in leukemia and other cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127555.RAcDR0sU2VwlmqeTwJepyzySG4KQGVBAGCvaVGGUdsgDQ130_provenance.
- NP127559.RAdEevAtx2HgP5Y9uu1ZSus0jMsUzB4wh_ouZssRf1BFs130_assertion description "[The MYB (dup) alteration was associated with T-cell acute leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127559.RAdEevAtx2HgP5Y9uu1ZSus0jMsUzB4wh_ouZssRf1BFs130_provenance.
- NP127561.RARZJqZJfa6c2ovmoDWHnxQdvN2RNb59TWDp2QMiNJyMw130_assertion description "[analysis of cytoplasmic function of mutant promyelocytic leukemia (PML) and PML-retinoic acid receptor-alpha ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127561.RARZJqZJfa6c2ovmoDWHnxQdvN2RNb59TWDp2QMiNJyMw130_provenance.
- NP127565.RATxSaNCfkfUnysuGtcVugim7031lYpLqseLGn7K82xLc130_assertion description "[higher level of NRP-1 mRNA was expressed in leukemias and NRP-1 promoted proliferation and chemotaxis of leukemic cells in response to VEGF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127565.RATxSaNCfkfUnysuGtcVugim7031lYpLqseLGn7K82xLc130_provenance.
- NP127566.RATT7hcdm0b1FQAeB936qYukRHKnXNTjTg1A9pjMZCwWk130_assertion description "[Fusion with RUNX1 may provide circumstantial evidence of an increased risk of relapse in leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127566.RATT7hcdm0b1FQAeB936qYukRHKnXNTjTg1A9pjMZCwWk130_provenance.
- NP127570.RAfQxMen_tavQWiDivhNhh0v2p8ClnTObNeG_l3D6xMW4130_assertion description "[CD154 can sensitize leukemia cells to apoptosis via the c-Abl-dependent activation of p73 and mitigate the resistance of p53-deficient CLL cells to anticancer drug therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127570.RAfQxMen_tavQWiDivhNhh0v2p8ClnTObNeG_l3D6xMW4130_provenance.
- NP127573.RAVrobLhqHvSizdQ-uVsVaR3u8Y-FzFU1xwEuNekCjMT4130_assertion description "[hTERT levels are significantly high in childhood acute lymphoblastic leukemia with the highest level of pre-B cell leukemia before treatment ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127573.RAVrobLhqHvSizdQ-uVsVaR3u8Y-FzFU1xwEuNekCjMT4130_provenance.
- NP127577.RAX2v4Q4A5IujlywpoKOcnERgs0X67TkBFV71quqHYrS4130_assertion description "[The silencing of USO-containing hERG1 isoforms induces a higher I (hERG1) density in tumors, an effect that apparently regulates neurite outgrowth in neuroblastoma cells and apoptosis in leukemia cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127577.RAX2v4Q4A5IujlywpoKOcnERgs0X67TkBFV71quqHYrS4130_provenance.
- NP127587.RAY61lkdiFilOBMD-Ig5dyBwCA9Ijn8i2VEnmfu7Q6AJ8130_assertion description "[Monitoring of the plasma level of sL-selectin is possibly useful for early diagnosis of relapse and extramedullary infiltration in acute leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127587.RAY61lkdiFilOBMD-Ig5dyBwCA9Ijn8i2VEnmfu7Q6AJ8130_provenance.
- NP127591.RAXpg5Hem2zqtx6lF1KwcQRFqdu9y2TpL2xgx4RJBZbQs130_assertion description "[alpha-lipoic acid controls cellular redox status, and upregulates quinone reductase NQO1 via Nrf2 activation in human leukemia HL-60 cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127591.RAXpg5Hem2zqtx6lF1KwcQRFqdu9y2TpL2xgx4RJBZbQs130_provenance.
- NP127592.RAUeEbLS3gOYwVeYW7jIEsmiStY0r0-47xWpxHnDdg8kc130_assertion description "[suppresses the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127592.RAUeEbLS3gOYwVeYW7jIEsmiStY0r0-47xWpxHnDdg8kc130_provenance.
- NP127599.RAannVxOdpTgRm0UysvkNQrvusKAfCMdChJeV78kXxo_g130_assertion description "[Anticancer-drug-induced apoptotic cell death in leukemia cells is associated with proteolysis of beta-catenin/plays a role in promoting Jurkat survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127599.RAannVxOdpTgRm0UysvkNQrvusKAfCMdChJeV78kXxo_g130_provenance.
- NP127601.RARY6h_nIkXimlnoxLFLNLlafxYS3oKzsPJkyUWU04gcg130_assertion description "[The response of promyelocytic leukemia nuclear bodies to DNA double-strand breaks is regulated by NBS1, ATM, Chk2, and ATR.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127601.RARY6h_nIkXimlnoxLFLNLlafxYS3oKzsPJkyUWU04gcg130_provenance.
- NP127603.RAQ5OFu7hqai_1zou1N_oWM6vK22XfvIETc8qc9Nrh8pA130_assertion description "[Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127603.RAQ5OFu7hqai_1zou1N_oWM6vK22XfvIETc8qc9Nrh8pA130_provenance.
- NP127606.RAamUMg4oXEsGsOhKsSYlqBhZz_p-iQGB6mjkXC0w3kj0130_assertion description "[GSTs play an important role in detoxifying the chemotherapeutic agents used to kill leukemia cells/simultaneous deletion of both the GSTM1 and GSTT1 genes is more predictive than any other parameter of early relapse of childhood B-precursor ALL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127606.RAamUMg4oXEsGsOhKsSYlqBhZz_p-iQGB6mjkXC0w3kj0130_provenance.
- NP127608.RAVorE2_z3-Eid1zoxTLu8OQXHMbu-dgeTn1pA-cXSy78130_assertion description "[leukemia SET-CAN fusion protein inhibited proliferation of U937 cells, most likely by interfering with hCRM1, but it also partially blocks differentiation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127608.RAVorE2_z3-Eid1zoxTLu8OQXHMbu-dgeTn1pA-cXSy78130_provenance.
- NP127610.RAXS4j_Ok9_OLmvulIWPoFcWqv0JZS25vb4h8DZfn6IOo130_assertion description "[Constitutive expression of cytokines in brain induces changes in gene expression characteristic of chronic inflammation leading to either temporal weight reduction (CNTF) or severe cachexia (leukemia inhibitory factor).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127610.RAXS4j_Ok9_OLmvulIWPoFcWqv0JZS25vb4h8DZfn6IOo130_provenance.
- NP127612.RASCkwJmiuUoTULn6Fi72O2ELL9bnJppMkKFSdRBSmWp8130_assertion description "[DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127612.RASCkwJmiuUoTULn6Fi72O2ELL9bnJppMkKFSdRBSmWp8130_provenance.
- NP127614.RATFeVnE2Os9CXlntctGY7liDJdCRRhgayzBeIwTiNZGE130_assertion description "[Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127614.RATFeVnE2Os9CXlntctGY7liDJdCRRhgayzBeIwTiNZGE130_provenance.
- NP127616.RAUsHflRffsANw87UYHokzUdOZb0dnpUClLJDGqRtewoE130_assertion description "[Results indicated that the JNK and Akt pathways and inhibition of NF-kappaB activity were key regulators of apoptosis in response to withaferin A in human leukemia U937 cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127616.RAUsHflRffsANw87UYHokzUdOZb0dnpUClLJDGqRtewoE130_provenance.
- NP127617.RARe_2Qm8vNA9Efm6fDkylRBwQmkGqGneRRvX1Tiy6dwQ130_assertion description "[Inhibition of ERK1/2 and activation of p38 are involved in diallyl disulfide induced apoptosis of leukemia HL-60 cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127617.RARe_2Qm8vNA9Efm6fDkylRBwQmkGqGneRRvX1Tiy6dwQ130_provenance.
- NP127632.RAUJVV9w2dorWGywngA7Xqn3K05f6jhL_wOxPyIqmNE38130_assertion description "[An analysis of 2, 162 case-controls demonstrated the first evidence of association between a BAT2 polymorphism (rs1046089) and severe malaria.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127632.RAUJVV9w2dorWGywngA7Xqn3K05f6jhL_wOxPyIqmNE38130_provenance.
- NP127633.RAVS4r3B_schYcC4fAHjpmsX_2VjZwus3ps2JYGPTuf0Q130_assertion description "[expression is increased in malaria, thus producing more nitric oxide ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127633.RAVS4r3B_schYcC4fAHjpmsX_2VjZwus3ps2JYGPTuf0Q130_provenance.
- NP127654.RAeilT--sKw3Ut5MBRtXh5jwW-rFROEXIh04dLjt8SMd4130_assertion description "[HLA-B23 and HLA-B46 allele are associated with severe malaria in endemic populations ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127654.RAeilT--sKw3Ut5MBRtXh5jwW-rFROEXIh04dLjt8SMd4130_provenance.
- NP127661.RAXLf0WDLOeBsIQ0JJ0FcECjDH7vZ71xMpQ8DzU7kUZMQ130_assertion description "[Patients with severe and mild malaria showed increased surface expression of TLR2 and TLR4 on CD14 (+) monocytes and myeloid dendritic cells and decreased intracellular expression of TLR9 on plasmacytoid dendritic cells compared to healthy controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127661.RAXLf0WDLOeBsIQ0JJ0FcECjDH7vZ71xMpQ8DzU7kUZMQ130_provenance.
- NP127674.RAYIsCcubZ-QiujOrjm1qjYZNB4bOZVY0Ql9UmyYS5Ato130_assertion description "[analysis of superoxide dismutase and catalase polymorphisms in smokers with COPD ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127674.RAYIsCcubZ-QiujOrjm1qjYZNB4bOZVY0Ql9UmyYS5Ato130_provenance.
- NP127677.RAZ6oMtNQHVel1AIpy5vfHhzgiB64KTdilBj7MIBUivys130_assertion description "[Plasma concentrations of IL-13 show associations with increasing severity of chronic obstructive lung disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127677.RAZ6oMtNQHVel1AIpy5vfHhzgiB64KTdilBj7MIBUivys130_provenance.
- NP127681.RAdRr7mROZ123zMGHXLVU61VEWHlkGE-IwGuiOua8EgQ8130_assertion description "[Blood oxygenation affects exercise-induced IL-6 response in hypoxemic chronic obstructive pulmonary disease patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127681.RAdRr7mROZ123zMGHXLVU61VEWHlkGE-IwGuiOua8EgQ8130_provenance.
- NP127684.RAbpUhGpvbHye0dgb191rK_LPaZO7XJnxlesMLX52ufyY130_assertion description "[polymorphisms in chronic obstructive pulmonary disease patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127684.RAbpUhGpvbHye0dgb191rK_LPaZO7XJnxlesMLX52ufyY130_provenance.
- NP127687.RAYsedvMSGd4K39aUKV6SbJv1HOdY4Gmfw0v6L7q-fqfQ130_assertion description "[Chronic obstructive pulmonary disease patients produce greater quantities of MMP-12 than controls ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127687.RAYsedvMSGd4K39aUKV6SbJv1HOdY4Gmfw0v6L7q-fqfQ130_provenance.
- NP127688.RAX9iNg0ScwdQNDKC4juAUbhr0mFHHT08dly6WO__6XsY130_assertion description "[Smoking and disease itself may stimulate MMP-12 expression in airway compartments (sputum and bronchoalveolar lavage) from chronic obstructive pulmonary disease patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127688.RAX9iNg0ScwdQNDKC4juAUbhr0mFHHT08dly6WO__6XsY130_provenance.
- NP127689.RAbBNpFLMShdiEByrDX1FB2ZMNJzcgeaapgQdE5u9_eYA130_assertion description "[There is distinct airways expression of TSLP and chemokines which preferentially attract T helper (Th) type 1- and Th2-type T cells, and influx of T cells bearing their receptors in asthma and chronic obstructive pulmonary disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127689.RAbBNpFLMShdiEByrDX1FB2ZMNJzcgeaapgQdE5u9_eYA130_provenance.
- NP127691.RAeKrF-5gZcqTZuoFAsLM8b5MxNIzNvUtpP7-UPSomqmM130_assertion description "[Determine pulmonary and systemic hepatocyte and keratinocyte growth factors in patients with chronic obstructive pulmonary disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127691.RAeKrF-5gZcqTZuoFAsLM8b5MxNIzNvUtpP7-UPSomqmM130_provenance.
- NP127693.RAT1mQS2onf4w7Aka-XS5eSWPafWxpsbIUQZ1gqlBz63c130_assertion description "[Cigarette smoke may directly cause the release of IL-8 from HASMC, an effect enhanced by TNF-alpha which is overexpressed in COPD ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127693.RAT1mQS2onf4w7Aka-XS5eSWPafWxpsbIUQZ1gqlBz63c130_provenance.
- NP127703.RAeRBmex8DIWP8_ahzl8FnWOFmDdGjV3r33TZl3TXdyn0130_assertion description "[Determine pulmonary and systemic hepatocyte and keratinocyte growth factors in patients with chronic obstructive pulmonary disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127703.RAeRBmex8DIWP8_ahzl8FnWOFmDdGjV3r33TZl3TXdyn0130_provenance.
- NP127707.RASMX5ns0WrDCaqZqlG690N3p8oR2yf2m2yyDVvpGYA4c130_assertion description "[Production of both TNFalpha and IL-10 in COPD lung tissue following exposure to bacterial LPS may have important biological implications for both episodes of exacerbation, disease progression and amelioration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127707.RASMX5ns0WrDCaqZqlG690N3p8oR2yf2m2yyDVvpGYA4c130_provenance.
- NP127717.RAZB1CkMepREJ4f3ubWcqPZTaE9T_ZWBw25EyDsZnaku0130_assertion description "[increased expression of NOS2 in bronchial tissue & smooth muscle cells in COPD patients; upregulation of NOS2 in COPD is involved in airway tone regulation & functional airflow limitation; increased arginase activity is involved in airway sensitivity ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127717.RAZB1CkMepREJ4f3ubWcqPZTaE9T_ZWBw25EyDsZnaku0130_provenance.
- NP127718.RAX-9A2SOiijab59I3cbciHBjn8x449N-R94M-lV9Hrrg130_assertion description "[ADRbeta2 genetic variations may affect beta-agonist responses in controlling brochoconstriction in asthma and chronic obstructive pulmonary disease, [REVIEW]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127718.RAX-9A2SOiijab59I3cbciHBjn8x449N-R94M-lV9Hrrg130_provenance.
- NP127719.RAUHesLKZszI4TRsqSQU--4mO4AXwAn9N_M86R1PDyNNw130_assertion description "[Beta2-adrenergic receptor polymorphisms may have roles in asthma and COPD in adults ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127719.RAUHesLKZszI4TRsqSQU--4mO4AXwAn9N_M86R1PDyNNw130_provenance.
- NP127722.RAZR1_uxoAqx2o6jxQYMZ6JYuiHMrlosDQrJDOQEus-uw130_assertion description "[p38 mitogen-activated protein kinase pathway activation appears to be involved in the pathogenesis of chronic obstructive pulmonary disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127722.RAZR1_uxoAqx2o6jxQYMZ6JYuiHMrlosDQrJDOQEus-uw130_provenance.
- NP127725.RAd6sYfkYfEY3bkdEunQxDZLpyCVpkk3qI7bpx0MpV8aE130_assertion description "[CD11b may play an important role in pathogenic process (in COPD) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127725.RAd6sYfkYfEY3bkdEunQxDZLpyCVpkk3qI7bpx0MpV8aE130_provenance.
- NP127734.RAVxEswoK9y1RXpWw40-TA2a1WwV8l6lI8ubpCP81WQ_8130_assertion description "[Data show that matrix metalloproteinase-9 expression in human lung parenchyma is associated with cigarette smoking and with obstruction of airflow, suggesting that MMP-9 may play a role in the pathogenesis of COPD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127734.RAVxEswoK9y1RXpWw40-TA2a1WwV8l6lI8ubpCP81WQ_8130_provenance.
- NP127745.RAUhqbjseBubbb55bMD0cLEFpQyrzy3eesnyUZ3qLafNQ130_assertion description "[Synthesized locally at mucosal sites/inhibit target enzymes released into interstitium/be important in controlling excessive neutrophil elastase release in chronic obstructive pulmonary disease and cystic fibrosis.(review) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127745.RAUhqbjseBubbb55bMD0cLEFpQyrzy3eesnyUZ3qLafNQ130_provenance.
- NP127747.RAWpoHilLAF2FKohSz223SHxjtyb2L72bARk1UTrg4LzY130_assertion description "[The CFTR M470V gene variant as a potential modifier of COPD severity in a Serbain population is reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127747.RAWpoHilLAF2FKohSz223SHxjtyb2L72bARk1UTrg4LzY130_provenance.
- NP127749.RAWJNBJW1uQu9QgPYxPDfKTR_Lhn4PV1pYa0oDqVjKgS0130_assertion description "[polymorphisms in chronic obstructive pulmonary disease patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127749.RAWJNBJW1uQu9QgPYxPDfKTR_Lhn4PV1pYa0oDqVjKgS0130_provenance.
- NP127751.RAXWLJT4yp4ZcRXY35Z_ZsMlmIUDjZqUgzhPlak1RjccE130_assertion description "[PDE4A4 is specifically up-regulated in macrophages from smokers with chronic obstructive pulmonary disease (COPD) and may provide a specific therapeutic target.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127751.RAXWLJT4yp4ZcRXY35Z_ZsMlmIUDjZqUgzhPlak1RjccE130_provenance.
- NP127756.RAWZ8DuuM-HePvvZjeGcIExJE7X6DE19mtPvgtFapKam4130_assertion description "[determination of whether the levels of complement factors C3a, C4a, and C5a are elevated at the site of inflammation in chronic obstructive pulmonary disease and in asthma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127756.RAWZ8DuuM-HePvvZjeGcIExJE7X6DE19mtPvgtFapKam4130_provenance.
- NP127760.RAYOxGQbxZ34go-THJ9Iq7p3GninMmuS3RSSH83q2YEJk130_assertion description "[Polymorphisms in the MBL2 gene reduce serum MBL levels in chronic obstructive pulmonary disease patients and are associated with risk of infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127760.RAYOxGQbxZ34go-THJ9Iq7p3GninMmuS3RSSH83q2YEJk130_provenance.
- NP127761.RAQFkieIoIUJhzCs0aDsUaXBktaJeAN4OnpLq9wL04i-k130_assertion description "[1 serine protease inhibitor genotype is a significant risk factor for chronic obstructive pulmonary disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127761.RAQFkieIoIUJhzCs0aDsUaXBktaJeAN4OnpLq9wL04i-k130_provenance.
- NP127762.RAbz1meO8lN_zMmJ7EmgdveWEQTrxz0-y_mQ-s-4qbYy4130_assertion description "[two novel polymorphisms in a conserved region of the SOD3 gene are associated with lung function or chronic obstructive pulmonary disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127762.RAbz1meO8lN_zMmJ7EmgdveWEQTrxz0-y_mQ-s-4qbYy4130_provenance.
- NP127763.RAbqK8kDdlo4VLVNPuaOu93sXwav0IeppoHM9l4Tf-TKI130_assertion description "[Angiotensin-converting enzyme and C-reactive protein may have roles in chronic obstructive pulmonary disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127763.RAbqK8kDdlo4VLVNPuaOu93sXwav0IeppoHM9l4Tf-TKI130_provenance.
- NP127767.RAVi4w_GY-xwUUvUPGItmTrMTwiOhux6bhDgrXAZWyepo130_assertion description "[MUC5B (mucin 5B) is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127767.RAVi4w_GY-xwUUvUPGItmTrMTwiOhux6bhDgrXAZWyepo130_provenance.
- NP127770.RAS5vSLjt611W2KQlUuLF2g_SZsGLG5KWBKwIlCVVgk_c130_assertion description "[The CYP2E1 and NAT2 variants associated with COPD ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127770.RAS5vSLjt611W2KQlUuLF2g_SZsGLG5KWBKwIlCVVgk_c130_provenance.
- NP127779.RARJ-cx_uwsQZrx-EoXbpqsK87VwQpjVUSHkmFGZs43iU130_assertion description "[The +2254A to G variant in intron 3 of AQP5 was associated with a decreased risk of COPD in a Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127779.RARJ-cx_uwsQZrx-EoXbpqsK87VwQpjVUSHkmFGZs43iU130_provenance.
- NP127780.RAS5bQWn4_jyqmS8m1huepHDCDViAujG3EtN3jlB84XvQ130_assertion description "[Findings suggest that the SLC11A1 polymorphisms could be used as markers for genetic susceptibility to chronic obstructive pulmonary disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127780.RAS5bQWn4_jyqmS8m1huepHDCDViAujG3EtN3jlB84XvQ130_provenance.
- NP127783.RAWHdJpIHRfIeS3AyimReLCAvya6aTiQPlj2A0INtePOE130_assertion description "[GLUT4 was reduced by 28% in vastus lateralis in chronic obstructive pulmonary disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127783.RAWHdJpIHRfIeS3AyimReLCAvya6aTiQPlj2A0INtePOE130_provenance.
- NP127784.RAftLR5sx0aXkuPvHRQgla3Zc_EpjtY1dzP4KjY8WtMf4130_assertion description "[The CYP2E1 and NAT2 variants associated with COPD ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127784.RAftLR5sx0aXkuPvHRQgla3Zc_EpjtY1dzP4KjY8WtMf4130_provenance.
- NP127787.RATdyycuiW_qRz11Ykprhec6ROlusU857WXounex09o4E130_assertion description "[The polymorphism of GSTP1 gene is linked to a genetic susceptibility to COPD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127787.RATdyycuiW_qRz11Ykprhec6ROlusU857WXounex09o4E130_provenance.
- NP127803.RAbqWNZWtcmsu_UoaNiVdx_z_HBBSle1hlRL24LHTvslc130_assertion description "[Production of both TNFalpha and IL-10 in COPD lung tissue following exposure to bacterial LPS may have important biological implications for both episodes of exacerbation, disease progression and amelioration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127803.RAbqWNZWtcmsu_UoaNiVdx_z_HBBSle1hlRL24LHTvslc130_provenance.
- NP127810.RAWUQqCkJhmc0zbCa0rKYyez8IkUNZo-dnIthkH5fxiRs130_assertion description "[Induced-sputum innate immune factor levels discriminate inflammatory changes in cystic fibrosis, COPD, and asthma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127810.RAWUQqCkJhmc0zbCa0rKYyez8IkUNZo-dnIthkH5fxiRs130_provenance.
- NP127811.RAdqiDvdb4-7Iw0zRJx-iQJy9U89o9FAcugVTkCQvfCzI130_assertion description "[polymorphisms in chronic obstructive pulmonary disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127811.RAdqiDvdb4-7Iw0zRJx-iQJy9U89o9FAcugVTkCQvfCzI130_provenance.
- NP127819.RAfK8xl8icfbhmlc910QXWfKs5r1bRr1Wa_0hgJ8Qa1g4130_assertion description "[Polymorphisms of eNOS contribute to disturbed pulmonary function and oxidative stress in Chronic Obstructive Pulmonary Disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127819.RAfK8xl8icfbhmlc910QXWfKs5r1bRr1Wa_0hgJ8Qa1g4130_provenance.
- NP127827.RAT7ufT_UVoWu3j8bURN0Mye7vNCUTrDFN-xYq5nNtEPA130_assertion description "[B7-H1 is expressed in muscle cells and may have a negative immune regulatory function in idiopathic inflammatory myopathies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127827.RAT7ufT_UVoWu3j8bURN0Mye7vNCUTrDFN-xYq5nNtEPA130_provenance.
- NP127828.RAe3v1xZo83uj548pmwUk8_2dQTv1DGBfG00GkN8dacXA130_assertion description "[The role of TLR3 in the immunobiology of muscle is reported; its implications for the understanding of the pathogenesis of inflammatory myopathies or therapeutic interventions are included.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127828.RAe3v1xZo83uj548pmwUk8_2dQTv1DGBfG00GkN8dacXA130_provenance.
- NP127833.RAbIwollVh_cen-HyZ7EVOOCN4fnYtX9R_6f0tCXLPT5I130_assertion description "[In sporadic inclusion-body myositis, UBB+1 may be pathogenic by inhibiting proteasome, thereby promoting accumulation of cytotoxic misfolded amyloid-beta and phosphorylated-tau.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127833.RAbIwollVh_cen-HyZ7EVOOCN4fnYtX9R_6f0tCXLPT5I130_provenance.
- NP127835.RAWbygeJ2ZiPqnVHWN2hVNBU1V-fbL9RhUHvwR1ZKIZDE130_assertion description "[The role of TLR3 in the immunobiology of muscle is reported; its implications for the understanding of the pathogenesis of inflammatory myopathies or therapeutic interventions are included.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127835.RAWbygeJ2ZiPqnVHWN2hVNBU1V-fbL9RhUHvwR1ZKIZDE130_provenance.
- NP127840.RAXx9zWcpCHbEVYWb9w_9lqFu-V81W719iAZTXxQmAcLY130_assertion description "[The selective expression of CCR7 in JDM may open new perspectives in the understanding of the pathogenesis of inflammatory myopathies, offering a new tool for the differential diagnosis of these disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127840.RAXx9zWcpCHbEVYWb9w_9lqFu-V81W719iAZTXxQmAcLY130_provenance.
- NP127845.RAXLs0crQlQ9BNMEdct3sEtCsjrT7LWUqv35tAZSnkHUw130_assertion description "[Human aspartyl (asparaginyl) beta-hydroxylase (HAAH) mRNA is overexpressed in biliary cancer cell lines and possibly involved in the pathogenesis of bile duct cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127845.RAXLs0crQlQ9BNMEdct3sEtCsjrT7LWUqv35tAZSnkHUw130_provenance.
- NP127846.RAZnLF029dywf0rwqVU3pJ-2Ns_wsD18FVSPZzIAiVnZE130_assertion description "[Homeobox B7 (HoxB7) mRNA is overexpressed in biliary cancer cell lines and possibly involved in the pathogenesis of bile duct cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127846.RAZnLF029dywf0rwqVU3pJ-2Ns_wsD18FVSPZzIAiVnZE130_provenance.
- NP127849.RATJVkkpcwxJVRrCnU4ugyTNlIgqBkez0Q4KS0FqDwzWQ130_assertion description "[Male carriers of the T allele of APOB IVS6+360C > T had a 2-fold risk of bile duct cancer/T-T haplotype had a 1.6-fold risk of bile duct cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127849.RATJVkkpcwxJVRrCnU4ugyTNlIgqBkez0Q4KS0FqDwzWQ130_provenance.
- NP127870.RAd3R-UwkvY7WVYXRE40hcsg5eQqxq5H_K59hPew1Cg1U130_assertion description "[Glycine N-methyltransferase is a favorable prognostic marker for human cholangiocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127870.RAd3R-UwkvY7WVYXRE40hcsg5eQqxq5H_K59hPew1Cg1U130_provenance.
- NP127876.RAfS0Y6AMOatN4goYr283iwjaWONcrOj6P3zOxVTXP50Q130_assertion description "[HBx gene transfection can upregulate the transcriptional expression of hTERT mRNA; transactivation of hTERT gene by HBx gene is a newfound mechanism for pathogenesis of hepatocarcinomas and cholangiocarcinomas after HBV infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127876.RAfS0Y6AMOatN4goYr283iwjaWONcrOj6P3zOxVTXP50Q130_provenance.
- NP127878.RAXU9IzC6cV_IsAVg48HLJJNkCcvnoL854idXu66PAHAI130_assertion description "[Our results suggest that the Hedgehog and ERK1/2 pathways are important for cholangiocarcinoma cell proliferation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127878.RAXU9IzC6cV_IsAVg48HLJJNkCcvnoL854idXu66PAHAI130_provenance.
- NP127879.RAY6SMfrmByGEX1X7FMnXKTAPTb42I1W5BdKPHW7bcG7w130_assertion description "[These results imply that ERK2 may be important for the differentiation of tubular-type cholangiocarcinoma (CCA).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127879.RAY6SMfrmByGEX1X7FMnXKTAPTb42I1W5BdKPHW7bcG7w130_provenance.
- NP127888.RARz5MCzD6pcngDF-dd28g_YTIRe5YSoNnPW7lDcf_t-4130_assertion description "[CDX2 expression was observed in 22 of the 59 (37.3%) cholangiocarcinoma cases, and was much higher in papillary-type than tubular-type cholangiocarcinoma (P = 0.002).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127888.RARz5MCzD6pcngDF-dd28g_YTIRe5YSoNnPW7lDcf_t-4130_provenance.
- NP127892.RAWzTXVVAl0nKHOKv6UbjJ4a8a3pO2VvV2kotw5YQLUwM130_assertion description "[Overexpression of CD24 is associated with intrahepatic cholangiocarcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127892.RAWzTXVVAl0nKHOKv6UbjJ4a8a3pO2VvV2kotw5YQLUwM130_provenance.
- NP127898.RAcBrpx1bCnmwdABXzdaWr3ucD9pjPACK8v2K1sUHssRc130_assertion description "[Overexpression of cyclin D1 is associated with cholangiocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127898.RAcBrpx1bCnmwdABXzdaWr3ucD9pjPACK8v2K1sUHssRc130_provenance.
- NP127902.RAd6NlH2F-TxKVik4pMRbH7IPgI_5DkLUYviqz4i4lC9k130_assertion description "[SOCS-3 epigenetic silencing is responsible for sustained IL-6/STAT-3 signaling and enhanced Mcl-1 expression in cholangiocarcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127902.RAd6NlH2F-TxKVik4pMRbH7IPgI_5DkLUYviqz4i4lC9k130_provenance.
- NP127904.RAfIpBch6FSZUUud7lmmUD4pGB0BmpCiJAMhvTvUhFDZA130_assertion description "[RASSF1A which we have been searching for at 3p21.3 may be one of the key tumor suppressor gene and play an important role in the pathogenesis of extrahepatic cholangiocarcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127904.RAfIpBch6FSZUUud7lmmUD4pGB0BmpCiJAMhvTvUhFDZA130_provenance.
- NP127906.RAQ9QRM4cYKyBg0OQqap8rSPWg7Zug-dJDNKHJMOhjX0I130_assertion description "[Overexpression of COX-2 plays crucial role in carcinogenesis and development of extra-hepatic cholangiocarcinoma, indicating that COX-2 may serve as target for chemoprevention of extra-hepatic cholangiocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127906.RAQ9QRM4cYKyBg0OQqap8rSPWg7Zug-dJDNKHJMOhjX0I130_provenance.
- NP127913.RAf1TmyUgx5VX4N3QA7aKUcp4vA3_ORuYVG6AzY4MODl8130_assertion description "[LAPTM4B-35 positively expressed in a great portion of extrahepatic cholangiocarcinoma and might be a novel molecular maker of progression, invasiveness and poor prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127913.RAf1TmyUgx5VX4N3QA7aKUcp4vA3_ORuYVG6AzY4MODl8130_provenance.
- NP127917.RAbjqMt0sDLoik9oe5PBvVrG-OksA4Cc4mGe4B0YnFzWY130_assertion description "[the DAPK gene epigenetically affected by methylation may be associated with the carcinogenesis of cholangiocarcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127917.RAbjqMt0sDLoik9oe5PBvVrG-OksA4Cc4mGe4B0YnFzWY130_provenance.
- NP127926.RARUMoOGLt-Pi8bHk9MjHFV7jvOYUxo1g0g4RfxBcigXM130_assertion description "[study suggests that the NAT2 polymorphism may be a modifier of individual risk to cholangiocarcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127926.RARUMoOGLt-Pi8bHk9MjHFV7jvOYUxo1g0g4RfxBcigXM130_provenance.
- NP127928.RAZiC5gAJXi2H3iYaaiZpkgEmZsJztTrJqZ0DHpSKidjE130_assertion description "[Amplification of the c-myc proto-oncogene occurs in hepatocellular carcinoma (HCC) and colorectal adenocarcinoma (MCA); its detection may have a useful diagnostic significance in differentiating intrahepatic cholangiocarcinoma (ICC) from MCA or HCC from ICC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127928.RAZiC5gAJXi2H3iYaaiZpkgEmZsJztTrJqZ0DHpSKidjE130_provenance.
- NP127930.RAaGlCTW3NErvhwMo8abla3MVp6OhJABX3gva2OCzJwq4130_assertion description "[The alterations of the p53 gene evaluated by DNA sequence analysis is relatively accurate/of P53 protein could not act as an independent index to estimate the prognosis of cholangiocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127930.RAaGlCTW3NErvhwMo8abla3MVp6OhJABX3gva2OCzJwq4130_provenance.
- NP127932.RAXeDKe7SdqLqVpW5BlbPs0o-ngBE8uKJucUJwR-lWqWE130_assertion description "[Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127932.RAXeDKe7SdqLqVpW5BlbPs0o-ngBE8uKJucUJwR-lWqWE130_provenance.
- NP127934.RARvPMpkK5GuSAop8nsojHoB-emPicju6vIquiDKmwf0c130_assertion description "[Her-2/neu protein overexpression by HER-2 gene amplification may occur in extrahepatic cholangiocarcinoma and constitute an independent prognostic factor in patients with lymph node metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127934.RARvPMpkK5GuSAop8nsojHoB-emPicju6vIquiDKmwf0c130_provenance.
- NP127939.RAfCRu1U8jEJO4h0tUYpuk6IyMWfFb5xCvzSYBWGm2soQ130_assertion description "[serum a-fetoprotein may have a similar role in intrahepatic cholangiocarcinoma and hepatocellular carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127939.RAfCRu1U8jEJO4h0tUYpuk6IyMWfFb5xCvzSYBWGm2soQ130_provenance.
- NP127940.RAZ12U316K-BX2Bgc4Q5kHtBw0KpFdmUla0MOpdlcnv7k130_assertion description "[In patients with cholangiocellular carcinoma, the presence of cells expresing Grp94 is related to CD83-positive dendritic cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127940.RAZ12U316K-BX2Bgc4Q5kHtBw0KpFdmUla0MOpdlcnv7k130_provenance.
- NP127945.RAQ8V2t08FpS5O6SNJytqn7NaZbEcIxuo_xTXAVF7igYM130_assertion description "[granulysin is involved in spontaneous abortion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127945.RAQ8V2t08FpS5O6SNJytqn7NaZbEcIxuo_xTXAVF7igYM130_provenance.
- NP127949.RAb3sTpKLMxIcJwheI5mindZxzQb_dbknBFRcowspZrK8130_assertion description "[The mutations of methylenetetrahydrofolate reductase C677T and A1298C play a role in the mechanism of unexplained recurrent spontaneous abortion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127949.RAb3sTpKLMxIcJwheI5mindZxzQb_dbknBFRcowspZrK8130_provenance.
- NP127950.RAW5SXYVG-uRYeO9mb1V7XeuCNFw_f1E5vF9fx8oYU8kM130_assertion description "[Findings suggest that genetic polymorphisms of plasminogen activator inhibitor-1 gene 4G/5G and 5, 10-methylenetetrahydrofolate reductase C677T were associated with recurrent early spontaneous abortion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127950.RAW5SXYVG-uRYeO9mb1V7XeuCNFw_f1E5vF9fx8oYU8kM130_provenance.
- NP127958.RAVb6pQ9WodwlNdsreqNBiQXgPdkbPctOTUEOeFlGlqI4130_assertion description "[The vasoconstrictively acting genotype NOS3 4/4 is of similar prevalence in recurrent spontaneous abortions patients and in controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP127958.RAVb6pQ9WodwlNdsreqNBiQXgPdkbPctOTUEOeFlGlqI4130_provenance.