Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP128809.RAVgeAx8R1NFBlLTu9XMMpsjvIUS5Slo6IsnHipJ0dLms130_assertion description "[novel pathogenic CDKL5 mutations were identified in three girls, two of whom had initially been diagnosed with the early onset seizure variant of Rett Syndrome (RTT) and the other with early onset seizures and some features of RTT ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128809.RAVgeAx8R1NFBlLTu9XMMpsjvIUS5Slo6IsnHipJ0dLms130_provenance.
- NP128814.RAVxa1N3GDeaZbzFm4xbRM21F7qkG8PQK0nsYznsfOqq8130_assertion description "[We broadened the clinical spectrum associated with SLC1A3 mutations to include milder manifestations of EA without seizures or alternating hemiplegia/severity of EA6 symptoms is related to the extent of glutamate transporter dysfunction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128814.RAVxa1N3GDeaZbzFm4xbRM21F7qkG8PQK0nsYznsfOqq8130_provenance.
- NP128818.RAW3MFMID9mj1T5VbPW9mFmq8FFooNCmZHK8D_3xBAiAU130_assertion description "[This study report an case of ombination of infantile spasms, non-epileptic seizures and complex movement disorder on the electroclinical features of a 4-year-old boy with an expansion of the trinucleotide repeat in the ARX gene ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128818.RAW3MFMID9mj1T5VbPW9mFmq8FFooNCmZHK8D_3xBAiAU130_provenance.
- NP128819.RAQgrT0FxTk6DX7vwPT_b3DVDM20FRAL31k_seE6PzYuw130_assertion description "[Mutational screening of CLCN2 gene, revealed a homozygous mutation G2003C (exon 17), leading to a Ser/Thr substitution at the codon 668, in two of the three in malignant migrating partial seizures patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128819.RAQgrT0FxTk6DX7vwPT_b3DVDM20FRAL31k_seE6PzYuw130_provenance.
- NP128820.RATwFj6cEf0AVYOYj0RfdEZhn7b53_GWI573WiJX65-0k130_assertion description "[serum and CSF S100B levels were raised in neruopsychiatric systemic lupus erythematosus, especially in patients with organic brain syndrome, seizures, cerebral vascular accident, and psychosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128820.RATwFj6cEf0AVYOYj0RfdEZhn7b53_GWI573WiJX65-0k130_provenance.
- NP128822.RAd3BR5uxAerHWt10PPxu3o0viYB-85WDo9_zb-RrtUPs130_assertion description "[report of a homozygous mutation of CNTNAP2 in Old Order Amish children with cortical dysplasia, focal epilepsy, relative macrocephaly, and diminished deep-tendon reflexes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128822.RAd3BR5uxAerHWt10PPxu3o0viYB-85WDo9_zb-RrtUPs130_provenance.
- NP128824.RAe3CkWgu0f0paKo1Z_ab67XhiCHWGXVeAtr5dtMgiODY130_assertion description "[A novel F318C substitution alters a highly conserved residue in a predicted repeat domain of LGI1 which may participate in the development of the " autosomal dominant partial epilepsy with auditory features " phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128824.RAe3CkWgu0f0paKo1Z_ab67XhiCHWGXVeAtr5dtMgiODY130_provenance.
- NP128826.RAZ4xZ-gw56JPbOpK28yp4AvUCdgV6Uw90HDzs4tH7azE130_assertion description "[mutations cause autosomal-dominant partial epilepsy with auditory features ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128826.RAZ4xZ-gw56JPbOpK28yp4AvUCdgV6Uw90HDzs4tH7azE130_provenance.
- NP128828.RAehcUxrUr8JrPB1KJEEvVggeXlaFFumbBtZTWYl-UD2E130_assertion description "[We found a nonsense mutation of SCN2A in a patient with intractable epilepsy and severe mental decline/phenotype is like severe myoclonic epilepsy in infancy but distinct because of partial epilepsy, delayed onset and no temperature sensitivity ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128828.RAehcUxrUr8JrPB1KJEEvVggeXlaFFumbBtZTWYl-UD2E130_provenance.
- NP128833.RAXUjVkbOfSSogMxQeYT4NCPu4t7-IkLpL_hy5gNQTUqE130_assertion description "[In patients with mesial temporal lobe epilepsy, mGluR1 may increase hippocampal excitability through postsynaptic activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128833.RAXUjVkbOfSSogMxQeYT4NCPu4t7-IkLpL_hy5gNQTUqE130_provenance.
- NP128835.RAY2CH7Jvmb6P_dYaLoS_NFC-7qSxS48tsD5KOt4v8WVU130_assertion description "[findings illustrate that SCN1A mutations can cause simple febrile seizures associated with temporal lobe epilepsy, which differ from the characteristic clinical spectrum of generalized epilepsy with febrile seizures plus ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128835.RAY2CH7Jvmb6P_dYaLoS_NFC-7qSxS48tsD5KOt4v8WVU130_provenance.
- NP128836.RAXOgEGaeWu6pWfO5GExYYvRyB7RXbJUr3QsEepabnB8E130_assertion description "[Data show that TLN2n presents only in the CSF of temporal lobe epilepsy patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128836.RAXOgEGaeWu6pWfO5GExYYvRyB7RXbJUr3QsEepabnB8E130_provenance.
- NP128837.RATaZIGbepsY-NgXqq6yZqflBIQKwxhBuWkNM-l2gNV-k130_assertion description "[the presence of Prnp variant alleles was found not to be significantly associated to cognitive performance of patients with mesial temporal lobe epilepsy with hippocampal sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128837.RATaZIGbepsY-NgXqq6yZqflBIQKwxhBuWkNM-l2gNV-k130_provenance.
- NP128838.RAQplWU8-030HMYBR3VPIFY12hqhFkELUS7LZNiUwWL6E130_assertion description "[This is the first publication of data that support the hypothesis that the common methionine/valine polymorphism at codon 129 of the PRNP gene may modify the susceptibility of women to mild temporal lobe epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128838.RAQplWU8-030HMYBR3VPIFY12hqhFkELUS7LZNiUwWL6E130_provenance.
- NP128840.RARTkNtq9z6YqnTTwMpyrQYwtagMsBp46ttV6YX9Gm3Fk130_assertion description "[Present data from a Chinese population fail to show a strong association of the variation at position -511 of the IL-1 beta gene promoter region in temporal lobe epilepsy patients with hippocampal sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128840.RARTkNtq9z6YqnTTwMpyrQYwtagMsBp46ttV6YX9Gm3Fk130_provenance.
- NP128841.RARtfwmTbToXvMJO9JQRJy8uDXq-Fu551NkmIGav8EaLE130_assertion description "[significant decrease of crmp-2 protein may represent or underlie impaired neuronal plasticity, neurodegeneration, wiring of the brain in mesial temporal lobe epilepsy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128841.RARtfwmTbToXvMJO9JQRJy8uDXq-Fu551NkmIGav8EaLE130_provenance.
- NP128844.RAQP0USED4Z8vj7FWLsZIY0HrCvVAkB6VPTEHYCj7AVGo130_assertion description "[In temporal lobe epilepsy, mutations in LGI1 are specific for autosomal dominant partial epilepsy with auditory features { ADPEAF } but do not occur in all families; ADPEAF is genetically heterogeneous ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128844.RAQP0USED4Z8vj7FWLsZIY0HrCvVAkB6VPTEHYCj7AVGo130_provenance.
- NP128846.RAS1kjnm1c1FuYeUCHMqNDfU8YQ3Mri3YjIqZ4L9lKaIU130_assertion description "[This report indicates pronounced adaptive changes in the expression of these GABA (A) receptor subunits related to seizure activity and indicates altered assembly of GABA (A) receptors in temporal lobe epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128846.RAS1kjnm1c1FuYeUCHMqNDfU8YQ3Mri3YjIqZ4L9lKaIU130_provenance.
- NP128849.RAc49PPKi501q-gzXry0SZIg4lSWmP_ENwJW1H061r65k130_assertion description "[The GABA (B [1]) polymorphism (G1465A) confers a highly increased susceptibility to temporal lobe epilepsy/, it seems to influence the severity of this common epileptic disorder ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128849.RAc49PPKi501q-gzXry0SZIg4lSWmP_ENwJW1H061r65k130_provenance.
- NP128851.RARueK0O1Te7or15PHXtsad1oA7qCMATh_pUOPGl5Elsk130_assertion description "[Patients with severe mesial temporal lobe epilepsy show reduced 5-HT1A receptor binding potential in the EEG-focus, and its limbic connections.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128851.RARueK0O1Te7or15PHXtsad1oA7qCMATh_pUOPGl5Elsk130_provenance.
- NP128853.RASKnq5M7Awo9aSRpD-bUmi3Ga20Ar5aXRx_eHVq_7J80130_assertion description "[Data show that vitamin D-binding protein (DBP) is elevated in the CSF of temporal lobe epilepsy patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128853.RASKnq5M7Awo9aSRpD-bUmi3Ga20Ar5aXRx_eHVq_7J80130_provenance.
- NP128857.RAROSSw8sO2Ry9JPN1cEcbdMZOuVbUu9NnSqxUYR23Jfg130_assertion description "[tendency towards association with the prodynorphin low expression (L) alleles was found in the small group of Autosomal dominant lateral temporal epilepsy index cases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128857.RAROSSw8sO2Ry9JPN1cEcbdMZOuVbUu9NnSqxUYR23Jfg130_provenance.
- NP128865.RAS_HmXJ4dwHyWc_KkWL5RcN6CkZ1GTRMtU9RoJS1piBE130_assertion description "[levels of CAD were significantly higher in the nuclear fraction of temporal lobe epilepsy samples ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128865.RAS_HmXJ4dwHyWc_KkWL5RcN6CkZ1GTRMtU9RoJS1piBE130_provenance.
- NP128867.RAVrINuTLSX6kLx-f2nUyLzDy5tdejRQxWPsO6l34N_dk130_assertion description "[cell loss and up-regulation of glutamate receptor subunits appear early in temporal lobe epilepsy and contribute to the synaptic plasticity that may facilitate the subsequent sprouting of mossy fiber collaterals ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128867.RAVrINuTLSX6kLx-f2nUyLzDy5tdejRQxWPsO6l34N_dk130_provenance.
- NP128869.RAeHu91irGU1TtoV88PlOvhidNhU76ahrlbdAxJ89DJh8130_assertion description "[cell loss and up-regulation of glutamate receptor subunits appear early in temporal lobe epilepsy and contribute to the synaptic plasticity that may facilitate the subsequent sprouting of mossy fiber collaterals ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128869.RAeHu91irGU1TtoV88PlOvhidNhU76ahrlbdAxJ89DJh8130_provenance.
- NP128874.RAZep00ngBJTV5R7xrr1i4hKyea_jYO5ajnDCDUvt2hq4130_assertion description "[Immunohistochemistry localized elevated p53 to a mainly nuclear distribution in neurons and glia in sections from temporal lobe epilepsy hippocampus ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128874.RAZep00ngBJTV5R7xrr1i4hKyea_jYO5ajnDCDUvt2hq4130_provenance.
- NP128875.RAYHL6DJN1vfiNgGzt9an62N37oxNZDz6nYcM0OX0c1Hg130_assertion description "[Highest expression of alphavbeta3 integrin is associated with metastatic potential of osteosarcoma cells by enhancing the ability of the cells to migrate specifically to the lung ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128875.RAYHL6DJN1vfiNgGzt9an62N37oxNZDz6nYcM0OX0c1Hg130_provenance.
- NP128876.RAddbOFDLqz7Gi-39KLA3smYwOAERxuPRvfivarH5T__k130_assertion description "[mediates adhesion of osteosarcoma to the core region of thrombospondin 1 (alpha 4 beta 1 integrin) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128876.RAddbOFDLqz7Gi-39KLA3smYwOAERxuPRvfivarH5T__k130_provenance.
- NP128881.RAUTDsPh3YII06kkoVn8FReNYqZa4avaUMzAYEkCblgUk130_assertion description "[mediates adhesion of osteosarcoma to the core region of thrombospondin 1 (alpha 4 beta 1 integrin) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128881.RAUTDsPh3YII06kkoVn8FReNYqZa4avaUMzAYEkCblgUk130_provenance.
- NP128886.RAXFjGzZA-HT2WIl-h6b_CsIbUYjrg09iQ_l-bPJ4za0U130_assertion description "[In cotransfection experiments with an osteocalcin (OC) promoter construct, we confirmed that only RUNX2wt and RUNX2Delta7 could upregulate the OC promoter activity in the osteosarcoma cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128886.RAXFjGzZA-HT2WIl-h6b_CsIbUYjrg09iQ_l-bPJ4za0U130_provenance.
- NP128888.RAZ5ydAqaB7IfHyL_VYMu5pv_6gCAm5jfd82VQme1nZz0130_assertion description "[alpha-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128888.RAZ5ydAqaB7IfHyL_VYMu5pv_6gCAm5jfd82VQme1nZz0130_provenance.
- NP128893.RAVEuc-7RhDCLf3xsSzXPK3bAr84rE7VBxvP1shLBATpE130_assertion description "[PEDF-overexpressing tumors exhibited reduced intratumoral angiogenesis, and PEDF may be a new and promising approach for the treatment of osteosarcoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128893.RAVEuc-7RhDCLf3xsSzXPK3bAr84rE7VBxvP1shLBATpE130_provenance.
- NP128899.RAXUgzcH55oQtcF7TQZ4KQa-n0yf2kOqw_Av3SADe2My4130_assertion description "[inactivation of p53 in osteosarcomas directly by mutation versus indirectly by HDM2 amplification may have different cellular consequences with respect to the stability of the genome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128899.RAXUgzcH55oQtcF7TQZ4KQa-n0yf2kOqw_Av3SADe2My4130_provenance.
- NP128900.RAXbOmwesrpd6FmlawiDdeWQSf_zhilNApbCZaA0TAZl0130_assertion description "[the number of p53 gene alterations in low-grade central osteosarcomas is lower than that in conventional high-grade osteosarcomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128900.RAXbOmwesrpd6FmlawiDdeWQSf_zhilNApbCZaA0TAZl0130_provenance.
- NP128904.RAcRB9UQ2GkgQkCkAlDgDBIgaEp7IDc7aBpKzEWf1uup0130_assertion description "[Cell surface expression of Her-2 is associated with osteosarcoma pathogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128904.RAcRB9UQ2GkgQkCkAlDgDBIgaEp7IDc7aBpKzEWf1uup0130_provenance.
- NP128906.RAXttVQO4ujHRwtvsdfSjE5NNTGFGHJup5nB6LuKHJP0M130_assertion description "[Expression of HER2/neu is not a poor prognostic factor in low-grade osteosarcoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128906.RAXttVQO4ujHRwtvsdfSjE5NNTGFGHJup5nB6LuKHJP0M130_provenance.
- NP128907.RAXnFNR-Lf8qKm-86wGHu4cHTmonFUSntOT22HcwX4v0w130_assertion description "[Her-2/neu overexpression in patients with osteosarcoma is associated with an increased risk of lung metastasis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128907.RAXnFNR-Lf8qKm-86wGHu4cHTmonFUSntOT22HcwX4v0w130_provenance.
- NP128908.RAfgiVrU4k7Sgx_pEsEWtZ8tr28JotXseUn_SOLtV3HQg130_assertion description "[Data show that patients with osteosarcomas with higher c-kit protein expression levels were significantly more likely to experience local disease recurrence and had a significantly lower survival time than patients with lower c-kit expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128908.RAfgiVrU4k7Sgx_pEsEWtZ8tr28JotXseUn_SOLtV3HQg130_provenance.
- NP128911.RAWgcjBZGHlK32a15_FPqx1GgsE8tgUNsaIhFzYbJTz6s130_assertion description "[c-Met and HGF-SF have roles in the growth and progression of human and canine osteosarcoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128911.RAWgcjBZGHlK32a15_FPqx1GgsE8tgUNsaIhFzYbJTz6s130_provenance.
- NP128912.RASKuI7ag5I4BsTqCzenC71Q-MewbuMyBefcIecvciEQ0130_assertion description "[genetic polymorphisms of the vitamin D receptor, estrogen receptor, and collagen Ialpha1 genes were characterized in 72 osteosarcoma and 53 Ewing sarcomas and in a group of 143 healthy matched children.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128912.RASKuI7ag5I4BsTqCzenC71Q-MewbuMyBefcIecvciEQ0130_provenance.
- NP128917.RAdcrS5-Dx0nxr7E5YZaSAs-C8OYm4fGD_1VxS3HyPyFc130_assertion description "[The proper combination of IFNalpha and conventional chemotherapeutic agents may be a rational strategy for the treatment of human osteosarcoma with functional p53.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128917.RAdcrS5-Dx0nxr7E5YZaSAs-C8OYm4fGD_1VxS3HyPyFc130_provenance.
- NP128918.RAbSRoZjfD30071zxlhMyHfKzNvIALSbsT0OpOFdY7BbA130_assertion description "[CLUAP1 (clusterin-associated protein 1) is highly expressed in osteosarcoma, ovarian, colon, and lung cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128918.RAbSRoZjfD30071zxlhMyHfKzNvIALSbsT0OpOFdY7BbA130_provenance.
- NP128922.RAYvOdPkLex-Uf-dXiR1Rt9cCoeEmgMlGf2-px6T3_xHw130_assertion description "[Alleleic loss at 10q26 in osteosarcoma is reported in the region of FGFR2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128922.RAYvOdPkLex-Uf-dXiR1Rt9cCoeEmgMlGf2-px6T3_xHw130_provenance.
- NP128929.RASmp3ak2GLnn27FMqGULEg5dOOd-cHZCN4F0aYJek9Ls130_assertion description "[DR5 expression is upregulated in human osteosarcoma cells after administration of sulforaphane ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128929.RASmp3ak2GLnn27FMqGULEg5dOOd-cHZCN4F0aYJek9Ls130_provenance.
- NP128930.RAfyiRFMHpNTeQjBex8eQe82ad7ltTxd3ZM018RqbwwCI130_assertion description "[a functional RANK expressed on osteosarcoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128930.RAfyiRFMHpNTeQjBex8eQe82ad7ltTxd3ZM018RqbwwCI130_provenance.
- NP128932.RAdz255jrxwmTkKOwF2hooXd8bVP_bnsBn8Zyw0g_KPo4130_assertion description "[High Livin expression is associated with osteosarcoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128932.RAdz255jrxwmTkKOwF2hooXd8bVP_bnsBn8Zyw0g_KPo4130_provenance.
- NP128933.RAZ1kWC9vVk21_d00-NnbC2uftmVv2GAgepyu3p05wEtY130_assertion description "[IGF-I activates specific apoptotic pathways (Caspase-3 activation, Annexin-V binding and DNA degradation in an osteosarcoma cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128933.RAZ1kWC9vVk21_d00-NnbC2uftmVv2GAgepyu3p05wEtY130_provenance.
- NP128939.RAR5IE4CrF9mNrIDzd1kjDS0oKWa_X_bwnQGWGzcYOIZI130_assertion description "[The expression of ephrin-B1 was correlated with a poorer clinical prognosis/protein was expressed by osteosarcoma cells and blood vessels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128939.RAR5IE4CrF9mNrIDzd1kjDS0oKWa_X_bwnQGWGzcYOIZI130_provenance.
- NP128941.RAbWnS3QwudVeyX6JJ9-m44KqKJU9sgLdTSqyKSrIwSos130_assertion description "[a link between RhoA, JNK, c-Jun, and MMP2 activity that is functionally involved in the reduction in osteosarcoma cell invasion by the statin/suggests a novel strategy targeting RhoA-JNK-c-Jun signaling to reduce osteosarcoma cell tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128941.RAbWnS3QwudVeyX6JJ9-m44KqKJU9sgLdTSqyKSrIwSos130_provenance.
- NP128944.RAZySwXbp91LMNboak4EszdfzQoC0HvH9h3xT1OxxbKlk130_assertion description "[Our data showed that MICA is prevalently expressed in osteosarcoma both in mRNA and protein level.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128944.RAZySwXbp91LMNboak4EszdfzQoC0HvH9h3xT1OxxbKlk130_provenance.
- NP128947.RAUE7QxfvsgAa1Inj3J9DiT8C7km9kxQK8MLGVX4Sh6lU130_assertion description "[The Poly (ADP-ribose) polymerase-1-regulated endonuclease DNAS1L3 is required for etoposide-induced internucleosomal DNA fragmentation and increases etoposide cytotoxicity in transfected osteosarcoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128947.RAUE7QxfvsgAa1Inj3J9DiT8C7km9kxQK8MLGVX4Sh6lU130_provenance.
- NP128952.RAT7EEjhzxSoghgRtKchSRYwfVGxMnist-wsdoM_Hdwms130_assertion description "[Bax gene therapy with cationic liposomes will be useful for osteosarcoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128952.RAT7EEjhzxSoghgRtKchSRYwfVGxMnist-wsdoM_Hdwms130_provenance.
- NP128958.RAblZgRjEIOqJV1_uL0hzYa2ncIBYCxJRivwZOUvqMKKM130_assertion description "[Ezrin and alpha-smooth muscle actin are predictive immunohistochemical prognostic markers for patients with an osteosarcoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128958.RAblZgRjEIOqJV1_uL0hzYa2ncIBYCxJRivwZOUvqMKKM130_provenance.
- NP128960.RAa4vPYd_sfU762PqMORUf4_kH2bmqHH-kTRa0zwuveQk130_assertion description "[Report expression of VEGF-C/VEGFR3 in osteosarcomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128960.RAa4vPYd_sfU762PqMORUf4_kH2bmqHH-kTRa0zwuveQk130_provenance.
- NP128963.RAczkGTAas-VpONnBPYo9NCG04K1snpo0EZfx8MMTgzbU130_assertion description "[Involvement of this protein in osteosarcoma biology and capability to identify novel therapeutic approaches targeting RANK-positive osteosarcomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128963.RAczkGTAas-VpONnBPYo9NCG04K1snpo0EZfx8MMTgzbU130_provenance.
- NP128965.RASJiE17XCw1wKGEpVyXmsF7TqmHXqUj4e_hjjyP86nis130_assertion description "[Caspase-8 protein expression is uniformly negative among patients with primary osteosarcoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128965.RASJiE17XCw1wKGEpVyXmsF7TqmHXqUj4e_hjjyP86nis130_provenance.
- NP128966.RAfdqKJKxtboXbyKHax4HgMcbAE-ErgbclqXKjC20W50M130_assertion description "[CDKIs mediate growth arrest in human osteosarcoma cell lines and provides further evidence of the existence of molecular links between cellular mortality and immortality.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128966.RAfdqKJKxtboXbyKHax4HgMcbAE-ErgbclqXKjC20W50M130_provenance.
- NP128967.RAa4CPzql-u3A83efbgBTQzCY22W4G2YJRX0a5P74yVPk130_assertion description "[senescence induced by the forced expression of p16 in early passage IMR90 fibroblasts or osteosarcoma U2OS cells was accompanied by expression of the two most acidic p16 variants ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128967.RAa4CPzql-u3A83efbgBTQzCY22W4G2YJRX0a5P74yVPk130_provenance.
- NP128969.RAYBAdq6PXmBRdFvyRCNrqloxN2KhCBEVD4y5CRDKYsn8130_assertion description "[Cell surface expression of EGFR is associated with osteosarcoma pathogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128969.RAYBAdq6PXmBRdFvyRCNrqloxN2KhCBEVD4y5CRDKYsn8130_provenance.
- NP128974.RAZ-vbB6bjcYgJT_hOanCRmxt4k0lyUW3tq__LGMLriD8130_assertion description "[IGF-I treatment stimulated cell growth and proliferation, but also mildly induces apoptosis in an osteosarcoma cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128974.RAZ-vbB6bjcYgJT_hOanCRmxt4k0lyUW3tq__LGMLriD8130_provenance.
- NP128975.RAf2otV-qas32jK42tbTFviOv-JqhkHK5sDpCCMEKQyS0130_assertion description "[c-Met and HGF-SF have roles in the growth and progression of human and canine osteosarcoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128975.RAf2otV-qas32jK42tbTFviOv-JqhkHK5sDpCCMEKQyS0130_provenance.
- NP128986.RAb9Yci5VSuSWUeIaRjQeo2KL496BrvH2TlfwlaGH1RhU130_assertion description "[zoledronate induces DNA damage and S phase arrest, accompanied by activation of the ATM/Chk1/cdc25 pathway in a human osteosarcoma cell line ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128986.RAb9Yci5VSuSWUeIaRjQeo2KL496BrvH2TlfwlaGH1RhU130_provenance.
- NP128991.RAYhUegQDUdfjT4wweSVgvq5zXyk6r1mxIRrGSrKkxDFk130_assertion description "[a link between RhoA, JNK, c-Jun, and MMP2 activity that is functionally involved in the reduction in osteosarcoma cell invasion by the statin/suggests a novel strategy targeting RhoA-JNK-c-Jun signaling to reduce osteosarcoma cell tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP128991.RAYhUegQDUdfjT4wweSVgvq5zXyk6r1mxIRrGSrKkxDFk130_provenance.
- NP129000.RAShAjNUZ0WUWbkKffmXiF3qE_lH4RHx8NGIpzIncLGUs130_assertion description "[Topors enhances the formation of high-molecular weight SUMO-1 conjugates of TOP1 in a reconstituted in vitro system and also in human osteosarcoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129000.RAShAjNUZ0WUWbkKffmXiF3qE_lH4RHx8NGIpzIncLGUs130_provenance.
- NP129001.RAUQl-H6o2aBpBvCr0ZITxjLdUwgMsGv7McRzIaNWKFhg130_assertion description "[Expression of SPP1 in osteosarcoma is associated with an inflammatory response and bone remodeling, making it a good biomarker.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129001.RAUQl-H6o2aBpBvCr0ZITxjLdUwgMsGv7McRzIaNWKFhg130_provenance.
- NP129003.RAXpGc_yMTtQVENpaP_cruWf0dQJNXObBPf0xdxq6IizY130_assertion description "[analysis of an exception to the decorin oncosuppression model using human osteosarcoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129003.RAXpGc_yMTtQVENpaP_cruWf0dQJNXObBPf0xdxq6IizY130_provenance.
- NP129004.RAY1R0j-wihluNHity-vPMhijhNprXw6tsVtVsb533V2A130_assertion description "[Overexpression of vitamin D receptor in MG-63 osteosarcoma cells induced the expression of histamine H1 receptor and dermatopontin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129004.RAY1R0j-wihluNHity-vPMhijhNprXw6tsVtVsb533V2A130_provenance.
- NP129006.RAfPCdGGgHUEZcTMIBHlAmgxAeffyhlvSHAslyMNzsUYE130_assertion description "[RMO1 is expressed and deleted in osteosarcoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129006.RAfPCdGGgHUEZcTMIBHlAmgxAeffyhlvSHAslyMNzsUYE130_provenance.
- NP129011.RAbCVUCiNKp4jdxAjFADhYYSu5XlWt1UgF5SiUyUGGcfo130_assertion description "[PXR plays a critical role in the regulation of P450 3A4 expression in osteosarcoma and that its expression and activation in these tumors may influence the effect of chemotherapeutic agents on the induction of target genes implicated in drug resistance ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129011.RAbCVUCiNKp4jdxAjFADhYYSu5XlWt1UgF5SiUyUGGcfo130_provenance.
- NP129019.RAc3n8k87pJXT52RT5WqJlG6807ZNW_68aoocS7OH2YVo130_assertion description "[Increase of CD44s, MMP-9, and Ki-67 were involved in the growth and local invasion of osteosarcoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129019.RAc3n8k87pJXT52RT5WqJlG6807ZNW_68aoocS7OH2YVo130_provenance.
- NP129026.RAflDOJtr1az6njk2gy2vDe2K6XDIrATz64r-_QBK4smk130_assertion description "[In glioma and osteosarcoma cells, endogenous merlin was targeted to the nucleus in a cell cycle-specific manner.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129026.RAflDOJtr1az6njk2gy2vDe2K6XDIrATz64r-_QBK4smk130_provenance.
- NP129032.RAT2c0Hf7w-1eJyRDv9BLzCSrMJaNJavhuelHHclaj8es130_assertion description "[Transfection of Dkk-3 and dominant-negative LRP5 into osteosarcoma cells significantly reduces invasion capacity and cell motility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129032.RAT2c0Hf7w-1eJyRDv9BLzCSrMJaNJavhuelHHclaj8es130_provenance.
- NP129033.RAXcZrRZeZS7yGlXL_bU4891l291LF_K96SdtZIqdIvB8130_assertion description "[while S100A6 is commonly overexpressed in human osteosarcoma, loss of its expression correlates with a metastatic phenotype ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129033.RAXcZrRZeZS7yGlXL_bU4891l291LF_K96SdtZIqdIvB8130_provenance.
- NP129034.RAcNFg37q0a2qDbPws5DA1X06R74xfVU2ux0ZhxiibqOk130_assertion description "[Ezrin and alpha-smooth muscle actin are predictive immunohistochemical prognostic markers for patients with an osteosarcoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129034.RAcNFg37q0a2qDbPws5DA1X06R74xfVU2ux0ZhxiibqOk130_provenance.
- NP129036.RARkAGsB_vHmqxDOxEMw9xOIanqHmTZgDmn1mBMZKvtIc130_assertion description "[a link between RhoA, JNK, c-Jun, and MMP2 activity that is functionally involved in the reduction in osteosarcoma cell invasion by the statin/suggests a novel strategy targeting RhoA-JNK-c-Jun signaling to reduce osteosarcoma cell tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129036.RARkAGsB_vHmqxDOxEMw9xOIanqHmTZgDmn1mBMZKvtIc130_provenance.
- NP129043.RAcpQJBoO2n7T3xL_jkteAUdeshmOFnyhzL6ZvQT0X7JQ130_assertion description "[cDNA microarray and quantitative RT-PCR analyses demonstrate that RANK-positive osteosarcoma cells are the target of RANKL as well as osteoclasts/osteoclast precursors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129043.RAcpQJBoO2n7T3xL_jkteAUdeshmOFnyhzL6ZvQT0X7JQ130_provenance.
- NP129053.RAXPfUf3BlcXEh7ucHcvjzdpgAAlMw_q5Ul3fnU7KUpFQ130_assertion description "[We describe two patients, a woman and her daughter, with muscle weakness and distal arthrogryposis (DA) type 2B, caused by a heterozygous missense mutation, R133W.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129053.RAXPfUf3BlcXEh7ucHcvjzdpgAAlMw_q5Ul3fnU7KUpFQ130_provenance.
- NP129054.RAdpyFwdr70AN2Y-3146LAZ4aqbEZv2ywg_PBpArrm320130_assertion description "[We describe a novel heart-hand syndrome involving familial cardiac myxomas and distal arthrogryposis and demonstrate that these disorders are caused by a founder mutation in the MYH8 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129054.RAdpyFwdr70AN2Y-3146LAZ4aqbEZv2ywg_PBpArrm320130_provenance.
- NP129058.RAfc2Mgl5XuLyhW_PBpn711LZ1Y50nO_q8evRxTWkQuxc130_assertion description "[mediastinal B-cell lymphoma and hodgkin lymphoma cells share overlapping features and defective tumor suppressor gene SOCS-1 triggers an oncogenic pathway operative in both Hodgkin and non-Hodgkin lymphomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129058.RAfc2Mgl5XuLyhW_PBpn711LZ1Y50nO_q8evRxTWkQuxc130_provenance.
- NP129064.RAS6GFuJDsLQWVq3e9z0AI0Wnb1JN-dpc64uLoUDzFE2M130_assertion description "[In Hodgkin's lymphoma Carriers of the IL-6-174GG genotype had a significantly lower probability of freedom from treatment failure ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129064.RAS6GFuJDsLQWVq3e9z0AI0Wnb1JN-dpc64uLoUDzFE2M130_provenance.
- NP129068.RAQpuCaACjD8AGJfQHofvgZQn_PF5e3T55-4WwJs_gNmo130_assertion description "[PD-1 is an immunomarker of follicular T-cell rosettes in nodular lymphocyte-predominant Hodgkin lymphoma and in a subset of lymphocyte-rich classic Hodgkin lymphomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129068.RAQpuCaACjD8AGJfQHofvgZQn_PF5e3T55-4WwJs_gNmo130_provenance.
- NP129072.RASSbSMoD-AU6urErQkjerV7dSznxzTpoEy1sOA1fzw7E130_assertion description "[Notch activation interferes with dedifferentiation of neoplastic B cells in Hodgkin lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129072.RASSbSMoD-AU6urErQkjerV7dSznxzTpoEy1sOA1fzw7E130_provenance.
- NP129078.RAReMB19DBUl90_pq_YptqAgT8Cx4rbfdlQBUZi02npYk130_assertion description "[Galectin-1 mediated suppression of Epstein-Barr virus specific T-cell immunity is associated with Hodgkin lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129078.RAReMB19DBUl90_pq_YptqAgT8Cx4rbfdlQBUZi02npYk130_provenance.
- NP129079.RAeWyZrkYnma_8XJLcopKFgetF1WH0dUWzrCS-gMgKios130_assertion description "[Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129079.RAeWyZrkYnma_8XJLcopKFgetF1WH0dUWzrCS-gMgKios130_provenance.
- NP129080.RAWLBm8kLI3bD1elj92uqw_U2MI2FXUJ86pLoDRwp2Oy4130_assertion description "[regulatory T cells and LAG-3 have pivotal roles in the suppression of EBV-specific cell-mediated immunity in Hodgkin lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129080.RAWLBm8kLI3bD1elj92uqw_U2MI2FXUJ86pLoDRwp2Oy4130_provenance.
- NP129081.RAaq8q8kRkBFBM1kkp0Uj5kl9AhOs4hBQIf5GprqHBgqk130_assertion description "[TopoIIalpha was an independent adverse predictor of failure-free survival in Hodgkin's lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129081.RAaq8q8kRkBFBM1kkp0Uj5kl9AhOs4hBQIf5GprqHBgqk130_provenance.
- NP129086.RAcr1WjVg-1qgTFvinHoylIF9J9uiWbRHBMhF2i7HdOjI130_assertion description "[Smac/DIABLO is differentially expressed in various types of B-cell non-Hodgkin lymphomas and Hodgkin lymphomas, suggesting that apoptotic mechanisms are differentially involved in the pathogenesis of these diseases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129086.RAcr1WjVg-1qgTFvinHoylIF9J9uiWbRHBMhF2i7HdOjI130_provenance.
- NP129088.RAYtRyTlA5UsQ-4fZxYtGqkKpIVcQP_6lRqA-ffmi9RGE130_assertion description "[Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129088.RAYtRyTlA5UsQ-4fZxYtGqkKpIVcQP_6lRqA-ffmi9RGE130_provenance.
- NP129089.RAQteK5REYX83NEAN0wLhpO9_-2AfI9P51BDFcTDIIu1k130_assertion description "[nutlin-3A stabilized p53 by preventing MDM2-mediated p53 degradation in and Reed-Sternberg (HRS) cells of Hodgkin's lymphoma (HL) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129089.RAQteK5REYX83NEAN0wLhpO9_-2AfI9P51BDFcTDIIu1k130_provenance.
- NP129092.RAdNW47YIoKeOp6wUJtCRZVrdGsoTK49UpPsZw6WgGah4130_assertion description "[p18INK4c may function as a tumor suppressor in Hodgkin lymphoma, and inactivation may contribute to cell cycle deregulation and defective terminal differentiation of the Reed-Sternberg cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129092.RAdNW47YIoKeOp6wUJtCRZVrdGsoTK49UpPsZw6WgGah4130_provenance.
- NP129102.RAUdq3qPJaYDlJ6kgZETnqymZmmsLjxrwdT80AJPaiyBA130_assertion description "[ERK5 probably mediates HOXB9 expression by repressing BMI1 in Hodgkin lymphoma cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129102.RAUdq3qPJaYDlJ6kgZETnqymZmmsLjxrwdT80AJPaiyBA130_provenance.
- NP129109.RAf7QyKDQZbqepWSzmIxYIuvZpbv07VzGAHPzuRueEL3k130_assertion description "[significantly higher positivity of c-REL protein expression in Reed-Sternberg cells in classic Hodgkin lymphoma was seen compared with positivity of lymphocytic and histiocytic (L & H) cells in nodular lymphocyte predominant Hodgkin lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129109.RAf7QyKDQZbqepWSzmIxYIuvZpbv07VzGAHPzuRueEL3k130_provenance.
- NP129111.RAU8Os_e3xYkV2_UBDgODC6Aeb4WWLYjBUxTDBokap_JY130_assertion description "[STAT6 overexpression detected in a classical Hodgkins lymphoma cell line ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129111.RAU8Os_e3xYkV2_UBDgODC6Aeb4WWLYjBUxTDBokap_JY130_provenance.
- NP129118.RAQU3KX43AzvZ1MBHpr5vQ-j8FJz7FDZ_xubRe-KRArdc130_assertion description "[Increased levels of VEGF in circulating blood is associated with non-Hodgkin's lymphoma or Hodgkin's lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129118.RAQU3KX43AzvZ1MBHpr5vQ-j8FJz7FDZ_xubRe-KRArdc130_provenance.
- NP129119.RAY6qL3FBGpC21gw_6e3xuj2OUJbHPDsM8Sek7MG5pNqc130_assertion description "[VEGF, HIF-1alpha, and predominantly PDGFRalpha are expressed in neoplastic cells in the majority of Hodgkin lymphomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129119.RAY6qL3FBGpC21gw_6e3xuj2OUJbHPDsM8Sek7MG5pNqc130_provenance.
- NP129132.RAYdP-vgzMuQ1mKRZvPfG3bRc1rb3eW9k6fqM9Ok8vA1Q130_assertion description "[nutlin-3A stabilized p53 by preventing MDM2-mediated p53 degradation in and Reed-Sternberg (HRS) cells of Hodgkin's lymphoma (HL) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129132.RAYdP-vgzMuQ1mKRZvPfG3bRc1rb3eW9k6fqM9Ok8vA1Q130_provenance.
- NP129147.RAXHm_eyIlRlwrYYEknmu83aK_t17mp74H3SCfiGEenns130_assertion description "[Elevated and highly expressed levels in both laarge B-cell lymphoma and Hodgkin lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129147.RAXHm_eyIlRlwrYYEknmu83aK_t17mp74H3SCfiGEenns130_provenance.
- NP129150.RAaZrq6le27pLi-Ussw_a7Rj0N7knfWhCAIqxTOn55Pus130_assertion description "[strong c-FLIP expression in nodular lymphocyte-predominant Hodgkin lymphoma was associated with transformation to diffuse large B-cell lymphoma; the majority of DLBCL cases tested were strongly c-FLIP-positive.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129150.RAaZrq6le27pLi-Ussw_a7Rj0N7knfWhCAIqxTOn55Pus130_provenance.
- NP129152.RAQRtoe85Au_e9nf6tc8zQHREukl4ZnaB85iyeR8AbeGo130_assertion description "[CD20 expression is frequent in classical Hodgkin's Lymphoma and our results are in consensus with reported literature on this subject.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129152.RAQRtoe85Au_e9nf6tc8zQHREukl4ZnaB85iyeR8AbeGo130_provenance.
- NP129157.RAdrQtL3drPYkC-h9gWNZp_PxmKjjPvJ-1aS6OuOHuKAc130_assertion description "[an immunohistochemical method to assess the ENT1 abundance of cells in tumor tissue was used to study ENT1 differential expression in Reed-Sternberg cells of Hodgkin's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP129157.RAdrQtL3drPYkC-h9gWNZp_PxmKjjPvJ-1aS6OuOHuKAc130_provenance.