Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP130326.RAUtRIalxcaKN3YSvR8ZZO93hjIyjAK2G4JoOA3YTSI_I130_assertion description "[PPARalpha, gamma DNA methylation induced by Hcy may represent an important mechanism to explain atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130326.RAUtRIalxcaKN3YSvR8ZZO93hjIyjAK2G4JoOA3YTSI_I130_provenance.
- NP130327.RAbUjqGY92iBv9y4rMsxN1b4u5Lvf1SupYM5x8WAe7xzg130_assertion description "[thrombomodulin level may be a molecular marker of the latent progression of atherosclerosis in hypertensive patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130327.RAbUjqGY92iBv9y4rMsxN1b4u5Lvf1SupYM5x8WAe7xzg130_provenance.
- NP130329.RAeo52MUm09e2AjKpL_nsHak9bVZ8a2iLXpjzX7OUEUIU130_assertion description "[Platelet microparticles may serve as transcellular delivery system for RANTES, triggering monocyte arrest; introducing a novel mechanism for platelet-dependent monocyte recruitment in inflammation and atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130329.RAeo52MUm09e2AjKpL_nsHak9bVZ8a2iLXpjzX7OUEUIU130_provenance.
- NP130331.RAfn3dNE5i-NO2SPX25xP7g3VBVPNh6vTc_m6cz6JLc0k130_assertion description "[The role of sPLA2-IIA in the perpetuation of atherosclerosis appears to be the missing link between inflammation, activated renin-angiotensin system and lipid peroxidation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130331.RAfn3dNE5i-NO2SPX25xP7g3VBVPNh6vTc_m6cz6JLc0k130_provenance.
- NP130333.RAa9Z2EpaUkRxEcFxAsjLUZCuCNd3vo9jTp6WUEws5lSU130_assertion description "[The P2Y12 H2 haplotype is associated with atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130333.RAa9Z2EpaUkRxEcFxAsjLUZCuCNd3vo9jTp6WUEws5lSU130_provenance.
- NP130339.RAQES47cOoRHp5f3Uhe9c6h55X_J-Sk9O8KH7q9oqPUNM130_assertion description "[endothelial RAGE and its ligands mediate vascular and inflammatory stresses that culminate in atherosclerosis in the vulnerable vessel wall ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130339.RAQES47cOoRHp5f3Uhe9c6h55X_J-Sk9O8KH7q9oqPUNM130_provenance.
- NP130342.RAW_pf91Doe8NaVzJOuxHnyFCUAzDfg20hAV9yXbW2GQg130_assertion description "[vWF and tPAag but not thrombomodulin in the present population are independent markers of atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130342.RAW_pf91Doe8NaVzJOuxHnyFCUAzDfg20hAV9yXbW2GQg130_provenance.
- NP130353.RASWm6ZkYNLr8NWXHmqoICT52g48RG5NeerynU-n7Wtjk130_assertion description "[Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130353.RASWm6ZkYNLr8NWXHmqoICT52g48RG5NeerynU-n7Wtjk130_provenance.
- NP130364.RAWbncFKOkXHsdWlg6QGYYp0GyUwr4hwtC4dfkm360qSA130_assertion description "[Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130364.RAWbncFKOkXHsdWlg6QGYYp0GyUwr4hwtC4dfkm360qSA130_provenance.
- NP130375.RAU2MYAK9nySqP5ufSH1-LejxP3Utn4ev1nBFlFTWSvnQ130_assertion description "[serpin A1 has an invasion-promoting effect in anaplastic large cell lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130375.RAU2MYAK9nySqP5ufSH1-LejxP3Utn4ev1nBFlFTWSvnQ130_provenance.
- NP130376.RAbgdXyE29qoOfzFTQPY3tt2BhzZVItuRzw-jQb8HwOpk130_assertion description "[constitutive expression of C/EBPbeta in ALK-positive anaplastic large cell lymphoma and its relationship to NPM-ALK ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130376.RAbgdXyE29qoOfzFTQPY3tt2BhzZVItuRzw-jQb8HwOpk130_provenance.
- NP130379.RAeyx41YkQjaf4CwgmifHyX2gjqNwmV1LhIFDZDgROxsI130_assertion description "[STAT3 directly contributes to the high level of TIMP1 expression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130379.RAeyx41YkQjaf4CwgmifHyX2gjqNwmV1LhIFDZDgROxsI130_provenance.
- NP130390.RAZP5CIVRlOCZgf7GCB0Rdo-dQ_ELnIEjQbecycw1TP9U130_assertion description "[CD26 and cell surface adenosine deaminase are selectively expressed on ALK-positive, but not on ALK-negative, anaplastic large cell lymphoma and Hodgkin's lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130390.RAZP5CIVRlOCZgf7GCB0Rdo-dQ_ELnIEjQbecycw1TP9U130_provenance.
- NP130403.RAQ1XVuujXIfkmyCDE5O3vyS-yxR37ekZT46ACuZ_Sn44130_assertion description "[Col6A3 fusion with colony-stimulating factor-1 gene is associated with tenosynovial giant cell tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130403.RAQ1XVuujXIfkmyCDE5O3vyS-yxR37ekZT46ACuZ_Sn44130_provenance.
- NP130404.RAcP9SCaudcCKkovS3ne40Ok1MIoypZrT3wLRQ7wwwkJI130_assertion description "[sarcomatous transformation of diffuse-type tenosynovial giant cell tumors involves aberrations of cyclin A, P53, and chromosome arm 15q ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130404.RAcP9SCaudcCKkovS3ne40Ok1MIoypZrT3wLRQ7wwwkJI130_provenance.
- NP130405.RAeGXjv10dUFm5lnAfkv9QTV-ojqExhHsY935oaE3QhmY130_assertion description "[sarcomatous transformation of diffuse-type tenosynovial giant cell tumors involves aberrations of cyclin A, P53, and chromosome arm 15q ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130405.RAeGXjv10dUFm5lnAfkv9QTV-ojqExhHsY935oaE3QhmY130_provenance.
- NP130406.RAQak8RgoHU-Fy0nOexGI-AUb6TPiRaiVkSAvpgjBT3FY130_assertion description "[EMMPRIN may be an important regulatory factor involved in the biological behaviors of giant cell tumor ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130406.RAQak8RgoHU-Fy0nOexGI-AUb6TPiRaiVkSAvpgjBT3FY130_provenance.
- NP130418.RAaMQDpeaDvAGjw8eiizF63-epsdKVO2qQRIJvK9RMrlQ130_assertion description "[These findings support CD1 genotype and protein expression as important risk markers for laryngeal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130418.RAaMQDpeaDvAGjw8eiizF63-epsdKVO2qQRIJvK9RMrlQ130_provenance.
- NP130421.RAS3gWUDGTZZNIYyvvn-hjru4OffsGJlM0uAan_Eiev6k130_assertion description "[These results indicate that some CAPN10 alleles may be exerting a protective effect on laryngeal cancer risk in the Spanish population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130421.RAS3gWUDGTZZNIYyvvn-hjru4OffsGJlM0uAan_Eiev6k130_provenance.
- NP130422.RAbPoZkgT0vNR_EybJyNYCKbyd3ivAhmbKphRlfDg7jTo130_assertion description "[Immunohistochemical analysis of Rb protein expression in neoplastic cells made it easier to evaluate the mechanisms of cancerogenesis in laryngeal cancer and is closely related to genetic alteration in Rb locus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130422.RAbPoZkgT0vNR_EybJyNYCKbyd3ivAhmbKphRlfDg7jTo130_provenance.
- NP130423.RARJd4HP1wOhwsp-u-9FM1o1DjEkFuSG0pqCXBRMmKUjQ130_assertion description "[NAT1 polymorphisms may be correlated with an increased risk of larynx cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130423.RARJd4HP1wOhwsp-u-9FM1o1DjEkFuSG0pqCXBRMmKUjQ130_provenance.
- NP130425.RAaPSKflRMbE0WCD4UEfu6sdzqBmMIc6nkRRfTw75W_NU130_assertion description "[The combined effect of N-acetyltransferase 2 (NAT2) slow genotype and exposure to smoking is observed during the development of laryngeal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130425.RAaPSKflRMbE0WCD4UEfu6sdzqBmMIc6nkRRfTw75W_NU130_provenance.
- NP130427.RAeDTvA0JvBs5C6_n0FuJ3HCdH11smspZETxDOn0q9IS4130_assertion description "[shRNA directed against hTERT inhibits telomerase activity through suppression of the hTERT expression in laryngeal cancer cells and that RNA interfering technology may be a promising strategy for the treatment of laryngeal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130427.RAeDTvA0JvBs5C6_n0FuJ3HCdH11smspZETxDOn0q9IS4130_provenance.
- NP130429.RAR6JaK8ANNGUa1Id5y2k_2egXM8RMSPYlyqnDab9bYcM130_assertion description "[Results suggest that GSTM1-deleted genotype may be a genetic susceptibility marker for laryngeal cancer, and that the absence of this enzyme may have a role in the development of laryngeal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130429.RAR6JaK8ANNGUa1Id5y2k_2egXM8RMSPYlyqnDab9bYcM130_provenance.
- NP130432.RAVb-oi7sZfpapVtQH0hq8nKwpfgsRpVLnB9HlfIpU8No130_assertion description "[P72R polymorphism in human papillomavirus associated premalignant laryngeal neoplasm ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130432.RAVb-oi7sZfpapVtQH0hq8nKwpfgsRpVLnB9HlfIpU8No130_provenance.
- NP130436.RAYPja9cOHF-pNNJVs-N48scKfezO5ulfgJlPbgyakJqw130_assertion description "[the G446A in ARLTS1 gene is probably not associated with an increased risk of sporadic breast cancer, prostate cancer, melanoma, thyroid papillary cancer or laryngeal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130436.RAYPja9cOHF-pNNJVs-N48scKfezO5ulfgJlPbgyakJqw130_provenance.
- NP130451.RATjh8volh1AZA24CMW6g2w44GwduBmUfMAeSg2dHS0WU130_assertion description "[Both hypoxia and heat shock prevented the lipopolysaccharide-induced increase in adult CD11b although it was unaltered in neonates.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130451.RATjh8volh1AZA24CMW6g2w44GwduBmUfMAeSg2dHS0WU130_provenance.
- NP130452.RAfxd_JE-bFslkXPk84bQstpkPSpSmf7nPbB9Q600onuU130_assertion description "[Findings reveal a unique role of the Mycobacterium tuberculosis heat shock protein 60 favouring development of Th2 type response by upregulating surface expression of TLR2 on macrophages which could be a survival strategy adopted by the bacilli.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130452.RAfxd_JE-bFslkXPk84bQstpkPSpSmf7nPbB9Q600onuU130_provenance.
- NP130462.RAbYIG65oYagfildXmePPCOfKOsLS99R6RCn5N-S-bgek130_assertion description "[polymorphisms possibly linked to genetic factors in Parkinson's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130462.RAbYIG65oYagfildXmePPCOfKOsLS99R6RCn5N-S-bgek130_provenance.
- NP130468.RAeYiOyDxqBgOQkqNd9Lu2acoq1UsX8r2zwu8HnJ3Yz5A130_assertion description "[Whether a polymorphism (g.168 _ 185del) within exon 1 of DJ-1 contributes to the risk of sporadic Parkinson disease in a Finnish case-control series was analyzed/gene does not play a major role in genetic predisposition to PD in this population ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130468.RAeYiOyDxqBgOQkqNd9Lu2acoq1UsX8r2zwu8HnJ3Yz5A130_provenance.
- NP130483.RARxwxuqwgxGHlnNGX31pjjrhgHpk5Q8VfjeueJd2ebMM130_assertion description "[Promoter polymorphism of the IL-8 gene is associated with Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130483.RARxwxuqwgxGHlnNGX31pjjrhgHpk5Q8VfjeueJd2ebMM130_provenance.
- NP130488.RAaoiLCg-rKL7Tt728kC1OagBxD3vE-T2OifpGQDxtppU130_assertion description "[A significant association between Parkinson disease & the slow acetylator genotype for N-acetyltransferase 2 in Hong Kong Chinesed provides evidence for a possible functional relationship between NAT2 slow acetylator genotype & PD in both racial groups.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130488.RAaoiLCg-rKL7Tt728kC1OagBxD3vE-T2OifpGQDxtppU130_provenance.
- NP130491.RAXVDelWuaxN7GGd5wA2-ja_fFBzOucHiPLjHD0cpxkW4130_assertion description "[CB1 receptor mRNA expression was altered in Parkinson's disease and was affected by alterations in dopaminergic systems.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130491.RAXVDelWuaxN7GGd5wA2-ja_fFBzOucHiPLjHD0cpxkW4130_provenance.
- NP130494.RAaWPBxEhFxsXv0LyAJJwJtrnfewSOYMYHertTqv0GsHY130_assertion description "[Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130494.RAaWPBxEhFxsXv0LyAJJwJtrnfewSOYMYHertTqv0GsHY130_provenance.
- NP130497.RASm9m4udSpxRwKJ9MBFM12NymQWIFVYiinbUgUfqW1LA130_assertion description "[FUBP1 is an authentic substrate of Parkin that might play an important role in development of Parkinson disease pathology along with aminoacyl-tRNA synthetase interacting multifunctional protein type 2 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130497.RASm9m4udSpxRwKJ9MBFM12NymQWIFVYiinbUgUfqW1LA130_provenance.
- NP130505.RAVicttzxRdG1ldpo94gLBQzz6Zc-T8Po2lwKtG6a_wMA130_assertion description "[SNP -1031C-863A in TNF-alpha promoter may act as a risk haplotype among Parkinson's disease cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130505.RAVicttzxRdG1ldpo94gLBQzz6Zc-T8Po2lwKtG6a_wMA130_provenance.
- NP130509.RAY7524fD4jGvG9Uh-5Z3cCNKzr3ObxyFNrJqEis6I7xI130_assertion description "[SCA2 is one of the genetic causes of Parkinson disease and multiple system atrophy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130509.RAY7524fD4jGvG9Uh-5Z3cCNKzr3ObxyFNrJqEis6I7xI130_provenance.
- NP130511.RAYCIL6JSy9BL3VyTeyOdd2cDk_3ltYtXTp-gCB8WvA5s130_assertion description "[Results describe the activity of ferroxidase, SOD1, and cofactors in CSF of patients with Parkinson's disease, Alzheimer's disease, Huntington's disease, or amyotrophic lateral sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130511.RAYCIL6JSy9BL3VyTeyOdd2cDk_3ltYtXTp-gCB8WvA5s130_provenance.
- NP130514.RAZblqSCSO-OFA33-FH6-f65g0vCabRx1AJdoAfCcpkQU130_assertion description "[rs760678 SNP of the NEDD9 gene is a weak genetic determinant of Alzheimer's disease and Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130514.RAZblqSCSO-OFA33-FH6-f65g0vCabRx1AJdoAfCcpkQU130_provenance.
- NP130517.RAfO8KCUAxJgDxAm0CUy3MAVKbrPpBP1NhGruMhhmgqw8130_assertion description "[Single nucleotide polymorphisms strongly support HIVEP3 as a candidate for PARK10 in Parkinson disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130517.RAfO8KCUAxJgDxAm0CUy3MAVKbrPpBP1NhGruMhhmgqw8130_provenance.
- NP130524.RAfH4KCwvchNLEHZaPIYdLm41V9RsAl1z49HmyLGE-41g130_assertion description "[Expression of ali1 promotes depolarization-dependent survival of cerebellar granule neurons/ali1 mapped to a chromosome 15 locus syntenic to candidate loci for familial Alzheimer's disease type 5 and Parkinson's disease 8 on human chromosome 12.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130524.RAfH4KCwvchNLEHZaPIYdLm41V9RsAl1z49HmyLGE-41g130_provenance.
- NP130525.RAajqZy8pbcZNdnJmxX_VMq2kOlUEx6VkC_Q13QWmk5nM130_assertion description "[a carrier of the founder CDKN2A [p.Leu113Leu; p.Pro114Ser]mutation as well as two MC1R moderate-risk variants, [p.Arg151Cys (+) p.Arg163Gln]developed 22 primary melanomas in the 3 years that followed initiation of levodopa therapy for Parkinson's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130525.RAajqZy8pbcZNdnJmxX_VMq2kOlUEx6VkC_Q13QWmk5nM130_provenance.
- NP130526.RAdeJXuev134w1bo5Yx5gs2q9OKYCAn5LmjOfmIlSxwLc130_assertion description "[Data show that basal level of interferon gamma is higher in Parkinson's disease patients than in healthy control subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130526.RAdeJXuev134w1bo5Yx5gs2q9OKYCAn5LmjOfmIlSxwLc130_provenance.
- NP130528.RAaT5TQre6aKUcCqSLJUocs5fZkz1OUzy5Ysj9dGs-0e0130_assertion description "[study demonstrates that GBA mutations are also encountered in Chinese subjects with sporadic Parkinson disease (PD) at higher frequency than many other PD genes & association of GBA mutations with development of PD is not related to ethnic origin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130528.RAaT5TQre6aKUcCqSLJUocs5fZkz1OUzy5Ysj9dGs-0e0130_provenance.
- NP130531.RATq_oXRJa4FyR_Of_a3vr_UhkbNDZ1YG64640moFyIEE130_assertion description "[The N370S allele of glucosidase, beta (nt.1226 A > G) may be associated with Parkinson's disease in patients of Jewish ethnicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130531.RATq_oXRJa4FyR_Of_a3vr_UhkbNDZ1YG64640moFyIEE130_provenance.
- NP130537.RAeev3_P02I9fHBnPsHyn1BETZ3r8OsHBxTemQxqTTbrY130_assertion description "[CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130537.RAeev3_P02I9fHBnPsHyn1BETZ3r8OsHBxTemQxqTTbrY130_provenance.
- NP130539.RAWWE9lh0maPW3uxVoKWr7aFHfsci5AsNuaL-vaDCb7Zg130_assertion description "[coexpression of Parkin degrades Pael-R and suppresses its toxicity; study implicates Parkin as a central player in the molecular pathway of Parkinson's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130539.RAWWE9lh0maPW3uxVoKWr7aFHfsci5AsNuaL-vaDCb7Zg130_provenance.
- NP130541.RAe05t0YYs78mu_w8C1oqdGwQ81r-iYHOyyiH7qt4umkw130_assertion description "[In this study found two patients carried PRKN mutations (p.G12R heterozygous and p.G430D homozygous) in early onset parkinson disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130541.RAe05t0YYs78mu_w8C1oqdGwQ81r-iYHOyyiH7qt4umkw130_provenance.
- NP130544.RAeL7nrG10QvkIEFNbj0Ci9QCLfA5YYDIv3sFITsXzYQo130_assertion description "[a novel and rare 1 bp insertion/nonsense mutation c1378 _ 1379insG (exon 12) and the entire deletion of exon 7 in early-onset Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130544.RAeL7nrG10QvkIEFNbj0Ci9QCLfA5YYDIv3sFITsXzYQo130_provenance.
- NP130546.RAS1ubfXFCYtQ4c7spFNXr5mK44lq9kCGHltiWA5L9jSM130_assertion description "[Homozygous Ser167 and Val380 are significantly associated with Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130546.RAS1ubfXFCYtQ4c7spFNXr5mK44lq9kCGHltiWA5L9jSM130_provenance.
- NP130547.RAQ0poBZZ_ZBrK6Lki3pxXEIZx2Mw52mNqMfmIKbfq5v8130_assertion description "[Among eastern Indian Parkinson disease patients, mutation in Parkin was identified in 7.24% cases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130547.RAQ0poBZZ_ZBrK6Lki3pxXEIZx2Mw52mNqMfmIKbfq5v8130_provenance.
- NP130551.RAfcyrouRXN4DEZssCx8LvbEE2aMvFkL5gjvfWwwekXPQ130_assertion description "[Parkin-positive patients appear to have a greater susceptibility to the exposure to dopaminergic medication than idiopathic Parkinson's disease patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130551.RAfcyrouRXN4DEZssCx8LvbEE2aMvFkL5gjvfWwwekXPQ130_provenance.
- NP130553.RAX8mYBSeC30bdkfl8fxzLV3yOUqe260p8xjt-EJJgF_Q130_assertion description "[leucine-rich repeat kinase 2 may be involved in a pathogenic pathway with other parkinson's disease (PD) -related proteins such as parkin, which may help illuminate both familial and sporadic PD ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130553.RAX8mYBSeC30bdkfl8fxzLV3yOUqe260p8xjt-EJJgF_Q130_provenance.
- NP130554.RAaeHGbTeWU1lreiZibGOGsWyR0oKCRMJnUxgOHnWKkWQ130_assertion description "[We confirm that synphilin-1 and parkin are components of majority of LBs in Parkinson's disease and that both proteins are susceptible to proteasomal degradation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130554.RAaeHGbTeWU1lreiZibGOGsWyR0oKCRMJnUxgOHnWKkWQ130_provenance.
- NP130564.RARK7vo-Hbmbjiad45DNiY2_WVmTZqUT9UYqOlnVS9vPc130_assertion description "[Homozygosity for a rare allele of the functional BDNF variant was associated with a 5.3-year older onset age for Parkinson disease, suggesting that BDNF may influence PD onset age.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130564.RARK7vo-Hbmbjiad45DNiY2_WVmTZqUT9UYqOlnVS9vPc130_provenance.
- NP130568.RAcHna64OoM7yfleAaK-1qvJjfgJj7u6wulw8aYEcxBCA130_assertion description "[Data demonstrate that 14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease, but there was no specific staining for the 14-3-3 eta subunit.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130568.RAcHna64OoM7yfleAaK-1qvJjfgJj7u6wulw8aYEcxBCA130_provenance.
- NP130575.RARIbnpuzvKuyBHm8uAuG0NF58nMugTSTKATZbnYDcQpI130_assertion description "[HS1PB3 protein is mutated in essential tremor combined with Parkinson disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130575.RARIbnpuzvKuyBHm8uAuG0NF58nMugTSTKATZbnYDcQpI130_provenance.
- NP130579.RAbHmpnjIicZkNpx0oaBXK0k5sqbEZnoK8BAW43xDGEMw130_assertion description "[LRRK2 R1628P may have a role in Parkinson's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130579.RAbHmpnjIicZkNpx0oaBXK0k5sqbEZnoK8BAW43xDGEMw130_provenance.
- NP130580.RAVY4klmZ6S_ALSLnRq_qXrhhCjX5JDUyyxGXlAjVLyPw130_assertion description "[LRRK2 is directly associated with the pathological structures of Parkinson's disease, dementia with Lewy bodies, and other related disorders using highly specific antibodies to LRRK2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130580.RAVY4klmZ6S_ALSLnRq_qXrhhCjX5JDUyyxGXlAjVLyPw130_provenance.
- NP130583.RAQTw-c5YFXb64Coxpkl6G2-AeQ2Mt6Gze2fyJHr_g-T4130_assertion description "[Comparison of evolutionary interspecies sequences of LRRK1 and LRRK2 suggests they diverged from a common founder gene implicated in Parkinson disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130583.RAQTw-c5YFXb64Coxpkl6G2-AeQ2Mt6Gze2fyJHr_g-T4130_provenance.
- NP130596.RAUjmczoddbWI1SHcgk-u68ok5Z9xMNUP4IiBEwmfpyHw130_assertion description "[the overall prevalence of the G2019S mutation in LRRK2 in German Parkinson's disease patients is apparently somewhat lower than in patients from other nearby European countries ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130596.RAUjmczoddbWI1SHcgk-u68ok5Z9xMNUP4IiBEwmfpyHw130_provenance.
- NP130598.RAXI9pRlcOUqImD-T3Ugy924eOPbr6ERf-4kEBT58hfk4130_assertion description "[Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130598.RAXI9pRlcOUqImD-T3Ugy924eOPbr6ERf-4kEBT58hfk4130_provenance.
- NP130610.RAQOIIiNmhTg1KMtT_kD8dIbX3imLZLjiL_E_w6UuDU0I130_assertion description "[These findings demonstrate that alpha-synuclein acts as a potent inflammatory stimulator of microglial cells, and that inhibitors of such stimulation might be beneficial in the treatment of Parkinson's disease and other synucleinopathies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130610.RAQOIIiNmhTg1KMtT_kD8dIbX3imLZLjiL_E_w6UuDU0I130_provenance.
- NP130614.RAR25q4Bub-WbiQVMak_CkaMUTucvLEPXMbz1qkUPZ1ck130_assertion description "[In this study 20-100% of alpha-synuclein-positive Lewy bodies in Parkinson disease patients contain LRRK2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130614.RAR25q4Bub-WbiQVMak_CkaMUTucvLEPXMbz1qkUPZ1ck130_provenance.
- NP130616.RAa1LBnh3FPc9KfMYu4zZi3PV3NXiCBxpn0lZaQu9hmUQ130_assertion description "[FGF20 is associated with Parkinson's disease synergistically with SNCA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130616.RAa1LBnh3FPc9KfMYu4zZi3PV3NXiCBxpn0lZaQu9hmUQ130_provenance.
- NP130619.RAYzhzWkLHgb8Xn5qAD7g_QYOo43TNp2i6MoHMANowjeg130_assertion description "[The distribution of the alleles of the dinucleotide repeats variants of alpha-synuclein gene promoter region in Parkinson's disease cases was significantly different from that in the healthy controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130619.RAYzhzWkLHgb8Xn5qAD7g_QYOo43TNp2i6MoHMANowjeg130_provenance.
- NP130624.RATPjSOU1UmBGaebXSv14q8wjyJ3KpDX0XkRGGcK7ugyY130_assertion description "[alpha-synuclein promoter polymorphism and smoking was associated with Parkinson's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130624.RATPjSOU1UmBGaebXSv14q8wjyJ3KpDX0XkRGGcK7ugyY130_provenance.
- NP130625.RAWWFIFO84HSXhKitzwQ2NuuTqxYqOljDnCOuBrnmhgh8130_assertion description "[Genotype-specific mean onset ages in Parkinson's disease displayed a trend of decreasing onset age with increasing allele size/variation in SNCA and its regulatory regions play an important role in both familial and sporadic PD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130625.RAWWFIFO84HSXhKitzwQ2NuuTqxYqOljDnCOuBrnmhgh8130_provenance.
- NP130627.RASeZg3n6vPNr3cysHdSrt9xwmglhJD_EKvWP-Qnky2XY130_assertion description "[The present study identifies an association of common SNCA polymorphisms with disease susceptibility in a series of Irish Parkinson's disease patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130627.RASeZg3n6vPNr3cysHdSrt9xwmglhJD_EKvWP-Qnky2XY130_provenance.
- NP130637.RARd_fUIOySKO9eD9HsaP74dv5GDOB8bLleKT50tg8C1U130_assertion description "[A patient homozygous for A PINK1 mutation was characterized clinically/clinical and laboratory features, including SPECT and assessment of autonomic function, were indistinguishable from typical idiopathic Parkinson disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130637.RARd_fUIOySKO9eD9HsaP74dv5GDOB8bLleKT50tg8C1U130_provenance.
- NP130638.RAdvWx-Dl8X4XoRVHvsQq4zC-2fCryxau4VbfUHXg3KqI130_assertion description "[PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130638.RAdvWx-Dl8X4XoRVHvsQq4zC-2fCryxau4VbfUHXg3KqI130_provenance.
- NP130641.RARpysEECbVsmHt5PvJi2wzJk6J5ZpbMimSTCezaE8jSU130_assertion description "[Data emphasize the importance of heterozygous PINK1 mutations as a possible risk factor for developing the common classic form of sporadic Parkinson disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130641.RARpysEECbVsmHt5PvJi2wzJk6J5ZpbMimSTCezaE8jSU130_provenance.
- NP130643.RAerl3d43RDehkVvanwx70rFu16IVZephNMv3ke1LLvt4130_assertion description "[PINK1 gene mutations are linked to Parkinson disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130643.RAerl3d43RDehkVvanwx70rFu16IVZephNMv3ke1LLvt4130_provenance.
- NP130645.RAVHyUrUD6jjG-_IHX7VGA30wXOzGXu2_v7KT6TpLLYss130_assertion description "[Absence of correlation between PINK1 mRNA levels and clinical status in heterozygous mutation carriers suggests that other genetic or environmental factors play a role in determining the phenotypic variability in Parkinson disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130645.RAVHyUrUD6jjG-_IHX7VGA30wXOzGXu2_v7KT6TpLLYss130_provenance.
- NP130651.RAXelQnGn1JVb753x2NK8RD-o3TMtiMQ8dA6-9aida2x4130_assertion description "[Study based on a small, well-characterized matched case-control group of patients with Parkinson disease (PD) suggests that the cholecystokinin system may influence the development of hallucinations in PD subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130651.RAXelQnGn1JVb753x2NK8RD-o3TMtiMQ8dA6-9aida2x4130_provenance.
- NP130660.RARWzeJ_xcaQ4wHEJRx67uvXv_Ho8sr9psEIKeb7FIzB4130_assertion description "[a haplotype across the sepiapterin reductase (SPR) gene, which is located in the PARK3 linkage region, modulates age of onset of Parkinson's disease in sibships.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130660.RARWzeJ_xcaQ4wHEJRx67uvXv_Ho8sr9psEIKeb7FIzB4130_provenance.
- NP130661.RAYswtRTVtnDSVOlW6l-ne_korVCJDtMz3MYRezkRaP8o130_assertion description "[genomic region in the proximity of IDE that may contribute to Alzheimer and Parkinson disease in a similar manner.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130661.RAYswtRTVtnDSVOlW6l-ne_korVCJDtMz3MYRezkRaP8o130_provenance.
- NP130662.RAdgzvJoPDiFzqMqPqL7F8fXXKhAixubTZd7QSiAfPnrM130_assertion description "[MEF2D levels were increased in the brains patients with Parkinson's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130662.RAdgzvJoPDiFzqMqPqL7F8fXXKhAixubTZd7QSiAfPnrM130_provenance.
- NP130667.RASoc88tGo-Ra1y1TPtAKQz3kjuQJmDF4_yTdaY4-oLBs130_assertion description "[results suggest a gain-of-function mechanism for LRRK2-linked disease with a central role for kinase activity in the development of Parkinson disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130667.RASoc88tGo-Ra1y1TPtAKQz3kjuQJmDF4_yTdaY4-oLBs130_provenance.
- NP130669.RAYsYJi7GyihULi-e2gYCSUJzQD8iULXA1OWccTQ4guSw130_assertion description "[the association of haptoglobin genotypes with the risk of Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130669.RAYsYJi7GyihULi-e2gYCSUJzQD8iULXA1OWccTQ4guSw130_provenance.
- NP130673.RAdbqGrYytsd8n7baI8fVdTw9I-QT6FXR_8_xkHwYR0Bw130_assertion description "[tetrahydrobiopterin-induced COX-2 expression is responsible for dopamine oxidation, leading to the preferential vulnerability of dopaminergic cells in Parkinson's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130673.RAdbqGrYytsd8n7baI8fVdTw9I-QT6FXR_8_xkHwYR0Bw130_provenance.
- NP130680.RAXc-IE6-5NXd9gMasWuCE89L1EzdPt3NQzWWRut_edLU130_assertion description "[The present study further explores the structural requirements for the cytotoxic effects of beta-carbolines and searches for additional compounds involved in the pathogenesis of Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130680.RAXc-IE6-5NXd9gMasWuCE89L1EzdPt3NQzWWRut_edLU130_provenance.
- NP130681.RAXTqGrWEz0A_tI29B120GuhFIajXvHXdsf5GpTgrDP7g130_assertion description "[Study reveals that allelic variants in SLC6A3, which affect gene expression, are associated with Parkinson's disease in this population and may interact with occupational pesticide exposure to increase PD risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130681.RAXTqGrWEz0A_tI29B120GuhFIajXvHXdsf5GpTgrDP7g130_provenance.
- NP130682.RAdfjY1fFPH3znDX5sh7QJAKv207oESvusmRSP-vgUhkU130_assertion description "[Measurement of striatal dopamine transporter in Parkinson's disease associated with the LRRK2 mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130682.RAdfjY1fFPH3znDX5sh7QJAKv207oESvusmRSP-vgUhkU130_provenance.
- NP130686.RASD1MD0L67FqCdQXxTrTUy_IzSy-N7IMfg5kxR9A1Zac130_assertion description "[Important issues regarding UCHL-1 and its role in Parkinson disease remain inconclusive, especially regarding the pathogenicity of the mendelian I93M mutation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130686.RASD1MD0L67FqCdQXxTrTUy_IzSy-N7IMfg5kxR9A1Zac130_provenance.
- NP130687.RAYwWXvnTFDHImVMl1rIGteRF5KwLn7hW9_BiKREg-zMU130_assertion description "[The identification of pathogenic mutations in the ubiquitin carboxy-terminal hydrolase L1 (UCHL1) has elucidated the ubiquitin proteasome system (UPS) and its potential role as a causal pathway in Parkinson's disease (PD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130687.RAYwWXvnTFDHImVMl1rIGteRF5KwLn7hW9_BiKREg-zMU130_provenance.
- NP130699.RAS2J2SqE3nu4lFON-ZMZE0G6EA8ODWYU4OTBBfpbsp0M130_assertion description "[Rb and its inactive phospho-isoform exhibit distinct expression patterns in Parkinson disease neurons most commonly associated with the disease, as well as in neurons elsewhere in the brain that also contribute to disease progression or symptoms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130699.RAS2J2SqE3nu4lFON-ZMZE0G6EA8ODWYU4OTBBfpbsp0M130_provenance.
- NP130700.RAbO76pqw1DgTv8s4uM3xcsIwL7JaariscZETCQCQSABY130_assertion description "[5-HT6 receptor gene polymorphism C267T is associated with Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130700.RAbO76pqw1DgTv8s4uM3xcsIwL7JaariscZETCQCQSABY130_provenance.
- NP130707.RAUj9zusepfPvJrO09F-VxmSjEHDmIGlwx--5l1ZT4Ryc130_assertion description "[Potentially modulates the onset of or risk for Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130707.RAUj9zusepfPvJrO09F-VxmSjEHDmIGlwx--5l1ZT4Ryc130_provenance.
- NP130710.RAV5_EQoYmStBEj9u9-s0W8S6Pb8k3fsYvlpdApeSzrWI130_assertion description "[ACE-II genotype was an independent risk factor for L-dopa-induced psychosis in Parkinson disease patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130710.RAV5_EQoYmStBEj9u9-s0W8S6Pb8k3fsYvlpdApeSzrWI130_provenance.
- NP130711.RAbBQzQxUb5i3TLlCK910hjcS1-FyKEX-GIQ-Jcvg6m8o130_assertion description "[phosphorylation state of Ser-129 in human alpha-synuclein determines neurodegeneration in a rat model of Parkinson disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130711.RAbBQzQxUb5i3TLlCK910hjcS1-FyKEX-GIQ-Jcvg6m8o130_provenance.
- NP130712.RAXvKi9zyYIItV5nfVIaHcvRWrGLHwtV1de8GFTv2RTjU130_assertion description "[Data show that the haplotypes of SEMA5A are associated with a risk of Parkinson's disease in a Chinese Han population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130712.RAXvKi9zyYIItV5nfVIaHcvRWrGLHwtV1de8GFTv2RTjU130_provenance.
- NP130717.RAaRfxuEmEhtyH-r4KmJcj3_KD54gmwu89y_l4T7stkO0130_assertion description "[magnitude of SERT binding reductions was greater in the forebrain than in the brainstem regions in early Parkinson's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130717.RAaRfxuEmEhtyH-r4KmJcj3_KD54gmwu89y_l4T7stkO0130_provenance.
- NP130738.RAW6kIMZcaGPMUA2Bw2N_8SjaTJuMvEtBGekK7i8SInAg130_assertion description "[role of synphilin-1 in synaptic function and protein degradation and in the molecular mechanisms leading to neurodegeneration in Parkinson disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130738.RAW6kIMZcaGPMUA2Bw2N_8SjaTJuMvEtBGekK7i8SInAg130_provenance.
- NP130752.RAdikJwbLQs2cIFHAZNRFPAZJPsvAp9BEMwl9pwEOWP9s130_assertion description "[possession of the HFE gene 282Tyr allele may offer some protection against the development of Parkinson Disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130752.RAdikJwbLQs2cIFHAZNRFPAZJPsvAp9BEMwl9pwEOWP9s130_provenance.
- NP130753.RAQLe0xOPWgFpRpLj4qoOV2__29tjkEHek34Xw_fDQZQY130_assertion description "[FGF20 is associated with Parkinson's disease synergistically with SNCA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130753.RAQLe0xOPWgFpRpLj4qoOV2__29tjkEHek34Xw_fDQZQY130_provenance.
- NP130760.RATzaLP-Xgor9rVEyc4xrs4cxUmgAcMsFAmZcMSO6hKcI130_assertion description "[the TT variant of the methylenetetrahydrofolate reductase C677T polymorphism is associated with an increased risk for Parkinson's disease in smokers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130760.RATzaLP-Xgor9rVEyc4xrs4cxUmgAcMsFAmZcMSO6hKcI130_provenance.
- NP130762.RAQPOsNxY8OwqIDLvTosY_VeikS5C7g_9lkQBOkhXQojw130_assertion description "[Two rare coding variants ss65713826 and ss65713830 were more frequent in patients than controls in norwegain Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130762.RAQPOsNxY8OwqIDLvTosY_VeikS5C7g_9lkQBOkhXQojw130_provenance.
- NP130766.RAXWrZdNGNxWGXokWosqNpV__olPey9j2vJZaQ4qNV634130_assertion description "[FUBP1 is an authentic substrate of Parkin that might play an important role in development of Parkinson disease pathology along with aminoacyl-tRNA synthetase interacting multifunctional protein type 2 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130766.RAXWrZdNGNxWGXokWosqNpV__olPey9j2vJZaQ4qNV634130_provenance.
- NP130768.RAcISHD-r-iKO-aWigDh0c9raU97JmgWL2Uj75Yf1i3TQ130_assertion description "[To investigate the role of SCA2 and SCA3 mutations in Chinese familial and early-onset Parkinson's disease (PD) patients, CAG triplet repeat expansions of SCA2 and SCA3 genes in 73 Taiwanese/Ethnic Chinese PD patients was analyzed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP130768.RAcISHD-r-iKO-aWigDh0c9raU97JmgWL2Uj75Yf1i3TQ130_provenance.