Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Information+about+MICB+allele+frequencies+and+haplotypes+with+HLA+in+Koreans. assertion.
- assertion asSentence MID1+coiled-coil+motifs+mediate+both+homo-+and+heterodimerization%2C+a+prerequisite+for+association+of+the+MID-alpha+4+complex+with+microtubules. assertion.
- assertion asSentence MID1+expression+is+tightly+regulated+through+concerted+action+of+alternative+promoters+and+alternative+polyadenylation+signals+both+during+embryonic+development+and+in+the+adult. assertion.
- assertion asSentence Structure+of+the+MID1+tandem+B-boxes+reveals+an+interaction+reminiscent+of+intermolecular+ring+heterodimers. assertion.
- assertion asSentence Has+no+conventional+cytokine+activity+but%2C+rather%2C+acts+to+modulate+and+amplify+the+response+to+lipopolysaccharide. assertion.
- assertion asSentence The+-173C+allele+in+the+promoter+region+is+associated+with+increased+rheumatoid+arthritis+predisposition%2C+mainly+in+early-onset+patients. assertion.
- assertion asSentence MIF+is+secreted+by+macrophages+upon+recognition+of+immune+complexes+and+is+required+for+TNF+production. assertion.
- assertion asSentence Restoration+of+contact+inhibition+in+human+glioblastoma+cell+lines+after+MIF+knockdown. assertion.
- assertion asSentence Hypoxia+significantly+affects+the+expression+of+HIF-1alpha+in+a+MIF-dependent+manner%2C+leading+to+a+positive-feedback+loop+in+primary+CD4+T+cells+and+influencing+the+lymphoproliferative+response+and+dexamethasone+action. assertion.
- assertion asSentence Gene+expression+is+predictive+for+the+individual+response+of+children+with+chronic+allograft+nephropathy+to+mycophenolate+mofetil. assertion.
- assertion asSentence Constitutive+NF-kappaB+activity+is+required+for+the+induced+gene+expression+of+CXCL9+in+tumour+cell+lines+in+response+to+IFNgamma. assertion.
- assertion asSentence Malaria-infected+primigravidae+with+placental+CXCL9+levels+in+the+lowest+tertile+gave+birth+to+babies+who+weighed+610+g+more+than+babies+born+to+mothers+with+high+CXCL9+levels. assertion.
- assertion asSentence First+dominant+cataract+mutation+in+MIP+that+is+located+outside+the+phylogenetically+conserved+transmembrane+domain. assertion.
- assertion asSentence MITF+regulates+p16INK4A+expression+in+melanocytes. assertion.
- assertion asSentence The+transcription+factor+MITF+is+an+amplified+oncogene+in+melanoma+that+is+critical+for+anchoring+lineage+dependence+and+malignant+character. assertion.
- assertion asSentence Normal+human+ataxin-3+is+a+striking+suppressor+of+polyglutamine+neurodegeneration+in+vivo. assertion.
- assertion asSentence Autophagy+is+involved+in+the+degradation+of+mutant+ataxin-3. assertion.
- assertion asSentence Expression+correlates+with+intensity+of+apoptosis+in+colorectal+adenocarcinoma. assertion.
- assertion asSentence A+useful+msarkser+in+patients+with+lung+adenocarcinoma. assertion.
- assertion asSentence Non-smoking+and+non-drinking+patients+with+squamous+cell+carcinoma+have+the+same+risk+for+developing+multiple+tumors+as+their+smoking+and+drinking+counterparts+without+an+increased+expression+of+Ki-67. assertion.
- assertion asSentence CD133+expression+positively+correlates+with+that+of+Ki-67+in+gastric+adenocarcinoma. assertion.
- assertion asSentence Patients+with+a+higher+expression+of+Ki67+has+a+better+tumor+response+to+the+chemotherapy. assertion.
- assertion asSentence FOXP1+expression+negatively+correlated+with+Ki67+expression+in+clear+cell+renal+cell+carcinomas+%28p+%3D+.036%29. assertion.
- assertion asSentence Women+with+a+HER2%2Fneu%2Fneu%2B%2FKi67%2B+ductal+carcinoma+in+situ+%28DCIS%29+have+a+higher+risk+of+developing+DCIS+local+recurrence+after+breast-conserving+surgery. assertion.
- assertion asSentence Defective+DNA+MMR+is+uncommon+in+long-term+survivors+of+pancreatic+cancer+and+does+not+account+for+the+survival+benefit+in+those+with+sporadic+pancreatic+cancer. assertion.
- assertion asSentence MLH1+is+associated+with+longevity. assertion.
- assertion asSentence The+immunohistochemical+expression+of+hMLH1+and+hMSH2+proteins+in+ovarian+cancer+has+no+predictive+value+in+resistance+to+cisplatin. assertion.
- assertion asSentence hMLH1+promoter+methylation+is+an+early+event+that+is+maintained+during+tumor+progression. assertion.
- assertion asSentence Methylation+of+the+3p22+region+encompassing+MLH1+is+representative+of+the+CpG+island+methylator+phenotype+in+colorectal+cancer. assertion.
- assertion asSentence MLH1+gene+promoter+methylation+is+associated+with+pancreatic+cancer. assertion.
- assertion asSentence Down-regulation+of+MLH1+is+associated+with+initiation+and+growth+of+neuroblastoma+and+brain+tumour+multicellular+spheroids. assertion.
- assertion asSentence p38+MAPK+inhibitors+SB202190+and+SB203580+activated+JNK+via+MLK-3%2FMKK7+pathway. assertion.
- assertion asSentence MLL-AF4+inhibits+or+activates+CDKN1B+expression. assertion.
- assertion asSentence WDR5+mediates+interactions+of+the+MLL1+catalytic+unit+both+with+the+common+structural+platform+and+with+the+histone+substrate. assertion.
- assertion asSentence Constitutional+duplication+11q23+de+novo+involves+the+MLL+gene. assertion.
- assertion asSentence Acute+myeloid+leukemia+cells+harbor+an+MLL+translocation+with+a+recurrent+partner+gene+of+MLL. assertion.
- assertion asSentence Lens+epithelium-derived+growth+factor+critically+associates+with+MLL+and+menin+at+the+nexus+of+transcriptional+pathways+that+are+recurrently+targeted+in+diverse+diseases. assertion.
- assertion asSentence Coexistence+of+alternative+MLL-SEPT9+fusion+transcripts+in+an+acute+myeloid+leukemia+with+t%2811%3B17%29%28q23%3Bq25%29. assertion.
- assertion asSentence MLL-MLLT10+gene+rearrangment+is+associated+with+mixed+phenotype+acute+leukemia. assertion.
- assertion asSentence Overexpression+of+MLL-AF4+fusion+protein+and+not+AF4-MLL+is+associated+with+t%284%3B11%29+leukemias. assertion.
- assertion asSentence MLL+duplication+is+associated+with+B-cell+lymphoblastic+lymphoma. assertion.
- assertion asSentence Expression+of+MLL-AF9+in+human+CD34%2B+cells+induces+acute+myeloid%2C+lymphoid%2C+or+mixed-lineage+leukemia+in+immunodeficient+mice. assertion.
- assertion asSentence The+forkhead+transcription+factor+AFX+activates+apoptosis+by+induction+of+the+BCL-6+transcriptional+repressor. assertion.
- assertion asSentence PIAS1+conjugates+SUMO-1+to+human+mineralocorticoid+receptor. assertion.
- assertion asSentence The+S810L+missense+mutation+of+the+mineralocorticoid+receptor+does+not+play+a+major+role+in+the+etiology+of+pregnancy-induced+hypertension+in+a+German+%2FTurkish+population. assertion.
- assertion asSentence %5Breview%5D+Rather+than+promiscuous%2C+the+mineralocorticoid+receptor+is+a+receptor+of+diverse+functions+%28including+the+long-term+control+of+blood+pressure%29+that+are+closely+regulated+by+ligand-specifying+mechanisms+only+now+becoming+clear. assertion.
- assertion asSentence Human+TRPM1+mutations+are+associated+with+the+complete+form+of+congenital+stationary+night+blindness+in+Japanese+patients. assertion.
- assertion asSentence NEP+mRNA+and+protein+are+expressed+mainly+by+the+epithelial+cells+and+to+a+minor+extent+by+the+stromal+cells+of+human+prostate+glands. assertion.
- assertion asSentence Truncating+mutations+in+MME+gene+in+fetomaternal+alloimmunisation+and+antenatal+membranous+glomerulopathies. assertion.
- assertion asSentence Expression+is+frequenty+decreased+in+chronic+myelogenous+leukemia. assertion.
- assertion asSentence CD10%2B+fibroblasts+are+more+involved+in+the+progression+of+hilar+and+extrahepatic+cholangiocarcinoma+than+of+peripheral+intrahepatic+cholangiocarcinoma. assertion.
- assertion asSentence High+CD10+expression+predicts+favorable+outcome+in+surgically+treated+lymph+node-positive+bladder+cancer+patients. assertion.
- assertion asSentence Membrane+type+1+matrix+metalloproteinase+regulates+cellular+invasiveness+and+survival+in+cutaneous+epidermal+cells. assertion.
- assertion asSentence Matrix+metalloproteinase+1+%28interstitial+collagenase%29is+upregulated+in+endothelial+cells+by+prostaglandin-J2. assertion.
- assertion asSentence General+role+for+elevated+MT1-MMP+in+promoting+both+the+selective+invasion+and+increased+growth+of+malignant+melanoma+in+vivo. assertion.
- assertion asSentence PHGPx+modulates+the+induction+of+MMP-1+and+collagenase. assertion.
- assertion asSentence MMP-1+in+the+stromal-tumor+microenvironment+can+alter+the+behavior+of+cancer+cells+through+PAR1+to+promote+cell+migration+and+invasion. assertion.
- assertion asSentence MMP-1+gene+polymorphisms+account+for+some+of+the+variability+in+the+progression+of+HCV-related+chronic+liver+diseases. assertion.
- assertion asSentence Monocyte+and+macrophage+cells+in+the+breast+tumor+microenvironment+play+an+important+role+in+the+modulation+of+MMP-1. assertion.
- assertion asSentence MMP-1+is+up-regulated+by+substance+P+to+promote+collagen+degradation+in+lung+fibroblasts. assertion.
- assertion asSentence Type+2+diabetes+LDL+lipoproteins+increasin+adhesion+molecules+by+promoting+increased+expression+of+MMP1. assertion.
- assertion asSentence IR%2Fvisible+light+spectrum+of+sunlight+significantly+increased+skin+MMP-1+expression. assertion.
- assertion asSentence Reactive+nitrogen+species+switch+on+early+extracellular+matrix+remodeling+via+induction+of+MMP1+and+TNFalpha. assertion.
- assertion asSentence No+association+between+polymorphism+and+overall+survival+or+progression+in+patients+with+esophageal+adenocarinoma+risk. assertion.
- assertion asSentence High+MMP-1+expression+is+associated+with+follicular+thyroid+neoplasms. assertion.
- assertion asSentence Advanced+oxidative+protein+products+treatment+increased+expression+of+MMP1+in+human+gingival+fibroblasts. assertion.
- assertion asSentence Dominant-negative+CK2alpha+induces+potent+effects+on+circadian+rhythmicity. assertion.
- assertion asSentence Overexpression+of+Tik+elicits+ectopic+bristles+in+N%28%2B%29+flies+and+suppresses+the+retinal+defects+of+the+gain-of-function+allele+N%28spl%29. assertion.
- assertion asSentence B52+delivers+Topo+I+to+RNA+polymerase+II-active+chromatin+loci+and+DNA+topology+and+mRNA+release+can+be+coordinated+to+control+gene+expression. assertion.
- assertion asSentence Circadian-clock-dependent+rhythms+in+GPRK2+abundance+control+the+rhythmic+accumulation+of+odorant+receptors+in+olfactory+sensory+neuron+dendrites. assertion.
- assertion asSentence Oscillations+in+GPRK2+levels+drive+rhythms+in+gustatory+physiology+and+behavior. assertion.
- assertion asSentence Trans-splicing+of+the+mod%28mdg4%29+complex+locus+is+conserved+between+the+distantly+related+species+Drosophila+melanogaster+and+D.+virilis. assertion.
- assertion asSentence Spn5+is+a+regulator+of+the+Toll+pathway+and+CHMP2B+toxicity+and+the+Toll+pathway+is+a+major+signaling+pathway+misregulated+by+mutant+CHMP2B+in+vivo. assertion.
- assertion asSentence Kon+is+enriched+at+myotube+tips+during+targeting+and+signals+through+the+intracellular+adaptor+Dgrip+in+a+conserved+molecular+pathway. assertion.
- assertion asSentence Deficiencies+of+CG15352%2C+the+gene+directly+upstream+of+e%28r%29%2C+are+not+associated+with+any+obvious+mutant+phenotypes+and+present+the+possibility+that+it+encodes+a+nonvital+or+redundant+function. assertion.
- assertion asSentence The+essential+Drosophila+melanogaster+gene+wds+%28will+die+slowly%29+codes+for+a+WD-repeat+protein+with+seven+repeats. assertion.
- assertion asSentence APLIP1%2C+a+kinesin+binding+JIP-1%2FJNK+scaffold+protein%2C+influences+the+axonal+transport+of+both+vesicles+and+mitochondria+in+Drosophila. assertion.
- assertion asSentence A+MAPK+docking+site+in+Capicua+is+critical+for+its+downregulation+by+Torso+and+EGFR+RTK+signaling. assertion.
- assertion asSentence Misregulation+of+CycB+contributes+to+the+disruption+in+behavior+of+follicle+stem+cell+progeny. assertion.
- assertion asSentence Zwilch+localizes+to+kinetochores+and+kinetochore+microtubules+in+a+manner+identical+to+ZW10+and+ROD. assertion.
- assertion asSentence Mutations+of+the+Drosophila+melanogaster+gene+CG31241+lead+to+high+frequency+chromosome+end+fusions. assertion.
- assertion asSentence Genetic+manipulations+in+Drosophila+melanogaster+that+impair+the+function+of+insulin-producing+cells+or+of+the+insulin-receptor+signaling+pathway+in+the+nervous+system+lead+to+increased+sensitivity+to+the+intoxicating+effects+of+ethanol. assertion.
- assertion asSentence Affects+gene+expression+regulation+in+Drosophila. assertion.
- assertion asSentence DSP1+and+corto+proteins+co-localize+at+91+sites+on+polytene+chromosomes+and+co-immunoprecipitate+in+embryos. assertion.
- assertion asSentence Rheb-TOR+signaling+controls+S2+cell+growth+by+promoting+ribosome+production+and+protein+synthesis%2C+not+by+direct+effects+on+the+import+of+amino+acids+or+glucose. assertion.
- assertion asSentence Coding+sequence+of+Ku70+gene+is+wild-type+in+two+mus309+mutant+lines. assertion.
- assertion asSentence Decrease+in+gene+dosage+causes+a+sharp+increase+in+the+frequency+of+HeT-A+and+TART+attachments+to+a+broken+chromosome+end+and+in+terminal+DNA+elongation+by+gene+conversion. assertion.
- assertion asSentence Role+for+Ku+subunits+in+the+regulation+of+sperm+individualization. assertion.
- assertion asSentence Kurzkern+mutant+embryos+fail+to+form+the+cephalic+furrow+and+do+not+accomplsh+germband+extension+and+nuclear+elongation+is+significantly+reduced. assertion.
- assertion asSentence The+Ndfip+promotes+their+activity+in+Notch+ubiquitination+and+internalization+to+the+lysosomal+lumen+for+degradation. assertion.
- assertion asSentence Upregulation+of+the+Nrf2+pathway+by+overexpressing+Nrf2+or+its+DNA-binding+dimerization+partner%2C+Maf-S%2C+restores+the+locomotor+activity+of+alpha-synuclein-expressing+flies. assertion.
- assertion asSentence Asap+forms+a+physical+complex+with+Cindr. assertion.
- assertion asSentence Swim+is+a+cofactor+that+promotes+long-range+Wg+signaling+in+vivo+by+maintaining+the+solubility+of+Wg. assertion.
- assertion asSentence Impairment+of+insulin+signalling+in+the+mushroom+body+neurons%2C+a+structure+involved+in+associative+learning%2C+impairs+feeding+behaviour+in+the+Drosophila+larva. assertion.
- assertion asSentence ATP6%281%29animals+compensate+for+their+loss+of+oxidative+phosphorylation+through+increases+in+glycolytic+flux%2C+ketogenesis+and+Kreb%27s+cycle+activity+early+during+pathogenesis. assertion.
- assertion asSentence The+complexity+employed+by+different+SWH+pathway+proteins+to+control+organ+size+at+different+stages+of+development. assertion.
- assertion asSentence ASF1+cellular+levels+are+tightly+controlled+by+distinct+pathways+and+provide+a+molecular+mechanism+for+post-translational+regulation+of+dASF1+and+hASF1a+by+TLK+kinases. assertion.
- assertion asSentence Phosphorylation+of+H3+is+linked+to+transcription+and+can+be+modulated+by+the+structure+of+the+promoter. assertion.
- assertion asSentence Rumi+is+a+CAP10+domain+glycerosyltransferase+that+modifies+Notch+and+is+required+for+Notch+signaling. assertion.
- assertion asSentence There+is+no+tight+functional+link+between+DmADA2a+and+DmRPB4. assertion.