Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP141942.RAXZ40NIJgIdPSNNVyDMCzLz4aTGH7KR2VpWcuvYyEVDE130_assertion description "[High FABP4 & low adiponectin levels are independent predictors of atherogenic dyslipidemia/plasma concentrations hold strong potential for development as a clinical biomarker for atherogenic dyslipidemia in type 2 diabetic subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141942.RAXZ40NIJgIdPSNNVyDMCzLz4aTGH7KR2VpWcuvYyEVDE130_provenance.
- NP141953.RAXeT2y6Mcw3IKMu33Qn8AHpD2BdyxrtJWIZfhjSXBfQE130_assertion description "[in patients with cardiovascular disease or dyslipidemia, adiponectin was independently positively associated with serum HDL-cholesterol, sVCAM-1 (vascular cell adhesion molecule 1), female gender and negatively with hs-CRP (C reactive protein) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141953.RAXeT2y6Mcw3IKMu33Qn8AHpD2BdyxrtJWIZfhjSXBfQE130_provenance.
- NP141957.RAa6mrd-4rF6Or1VEiYyQjvmtPf2EssTXJLxSv0_q2JyE130_assertion description "[Excess risk for low HDL-Cholesterol, dyslipidemia and metabolic syndrome is associated with the rare alleles of the APOA5 SNPs and non-carriers of common haplotype in women ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141957.RAa6mrd-4rF6Or1VEiYyQjvmtPf2EssTXJLxSv0_q2JyE130_provenance.
- NP141960.RAX1OIE9syVgDQcxOkEJpHnRkK69-nNgUyhGL3TEj5PzY130_assertion description "[atheroprotective role of hApoA5 in a transgenic mouse model of mixed dyslipidemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141960.RAX1OIE9syVgDQcxOkEJpHnRkK69-nNgUyhGL3TEj5PzY130_provenance.
- NP141961.RAUZh44lg6HiTMYM0VOhm0i-_T8IqeL2Z3tepPpEPDmWE130_assertion description "[exon 9 PIK3CA mutations are typical of infiltrating lobular carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141961.RAUZh44lg6HiTMYM0VOhm0i-_T8IqeL2Z3tepPpEPDmWE130_provenance.
- NP141965.RAYJVOMLX-Qg1RC-5-qIKQdGYOAajSU-rPDqavNICHr5A130_assertion description "[Histiocytoid features of invasive lobular carcinoma is immunopositive for MUC5AC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141965.RAYJVOMLX-Qg1RC-5-qIKQdGYOAajSU-rPDqavNICHr5A130_provenance.
- NP141972.RAX04n4_Hy1uQTbLLKS6t0puWOXaJ55A5qngNhj7cdwYc130_assertion description "[Loss of CD34+ fibrocytes is not a consistent feature of invasive lobular carcinomas of the breast/preserved CD34+ stromal cell population does not exclude malignancy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141972.RAX04n4_Hy1uQTbLLKS6t0puWOXaJ55A5qngNhj7cdwYc130_provenance.
- NP141974.RAcv4QlweUqdIlPSFCeP783S3DAPBZRy4pQboqpjNea8A130_assertion description "[Expression of NKX3.1 is highly restricted and is found primarily in benign and malignant prostatic epithelial cells and also in normal testis and lobular carcinoma of the breast.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141974.RAcv4QlweUqdIlPSFCeP783S3DAPBZRy4pQboqpjNea8A130_provenance.
- NP141978.RASSOPjXPf-QBhfQxVPuml3svsMs-7m9sG84V_mfngZHU130_assertion description "[Uncertain pathogenicity of MSH2 variants N127S and G322D in genetic predisposition for colorectal, endometrial, pancreatic and biliary tract neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141978.RASSOPjXPf-QBhfQxVPuml3svsMs-7m9sG84V_mfngZHU130_provenance.
- NP141982.RATnPRPNz5IXTqF5Yb76JkFx6hN9J7N5-K-pR2gAJcm-o130_assertion description "[Demonstrated epigenetic silencing by MGMT promoter hypermethylation might play an important role in carcinogenesis and progression of biliary tract cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141982.RATnPRPNz5IXTqF5Yb76JkFx6hN9J7N5-K-pR2gAJcm-o130_provenance.
- NP141986.RAVd7b5lVxjyPaqHnHV8Mv_TYJzbr2TPA5ctz3JhpCPG0130_assertion description "[We believe that CD44s-mediated adhesion of malignant cells to other cells or to the extracellular matrix is responsible for the invasive features of biliary tract neoplasms, its aggressive progression, and its resistance to treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141986.RAVd7b5lVxjyPaqHnHV8Mv_TYJzbr2TPA5ctz3JhpCPG0130_provenance.
- NP141987.RAZTKdj6jMRA-nYQCfc1yMbSsx3PW2ItSBUx-6OBgnTbc130_assertion description "[study identified aberrant p16INK4 expression in different stages of urothelial lesions; urothelial carcinoma in situ showed overexpression of p16INK4, suggesting a role of INK4a mutation as an early event of bladder carcinogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141987.RAZTKdj6jMRA-nYQCfc1yMbSsx3PW2ItSBUx-6OBgnTbc130_provenance.
- NP141997.RASitJz7jX8P1N51-OxQxv22yuu_5zkFZ4gCBiX-Tumns130_assertion description "[significantly more overexpression of DcR3 in high-grade dysplasia or carcinoma in situ and esophageal adenocarcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141997.RASitJz7jX8P1N51-OxQxv22yuu_5zkFZ4gCBiX-Tumns130_provenance.
- NP141998.RAebzbcM8RB_cugdXTY-GcYIK8aMB6KFZm6wOxucq1k4E130_assertion description "[Correlated with degree of differentiation/in undifferentiated basalioma and strongly expressed in carcinoma in situ, keratoacanthoma, and differentiated squamous cell carcinoma/in superficial, differentiated region of normal epithelium.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141998.RAebzbcM8RB_cugdXTY-GcYIK8aMB6KFZm6wOxucq1k4E130_provenance.
- NP141999.RAUeMXWimmWJquNm1U6ddvCVNFmsBpdKPMQfRKpbra2Qw130_assertion description "[Correlated with degree of differentiation/in undifferentiated basalioma and strongly expressed in carcinoma in situ, keratoacanthoma, and differentiated squamous cell carcinoma/in superficial, differentiated region of normal epithelium.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP141999.RAUeMXWimmWJquNm1U6ddvCVNFmsBpdKPMQfRKpbra2Qw130_provenance.
- NP142000.RAUL6csilj4OeEKtrh5XsqMo0kI9qt6KSuvIqirfZdcUg130_assertion description "[MMP-2 immunostaining was positive in 4 of 8 cases of invasive carcinoma and stained stromal area around tumor nest/metalloproteinases are activated in carcinoma in situ and in cervical intraepithelial neoplasia of uterine cervix.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142000.RAUL6csilj4OeEKtrh5XsqMo0kI9qt6KSuvIqirfZdcUg130_provenance.
- NP142007.RAaFRsfTM5n_S4QdNYBpUBFHPAFYHXGpmCUeeYg-6t90g130_assertion description "[ARHI may have a role in development and progression of ductal breast carcinoma in situ ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142007.RAaFRsfTM5n_S4QdNYBpUBFHPAFYHXGpmCUeeYg-6t90g130_provenance.
- NP142010.RASgRd-pH9q7SLHv7zrtGYHT4OBC5SlAqBviF3WJuqixY130_assertion description "[The CCND1 variant A allele may recessively increase the risk of carcinoma in situ incidence in patients with superficial bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142010.RASgRd-pH9q7SLHv7zrtGYHT4OBC5SlAqBviF3WJuqixY130_provenance.
- NP142017.RAYDtlIINi1WAK2c5IqRzsPu4YzqrR7Oeh3Tkl92dqxFY130_assertion description "[FHIT underexpression was detected in 27% of carcinoma in situ and 41% of invasive carcinoma, which suggests that it could be useful in assessing those carcinoma in situ lesions (ductal, DCIS and lobular, LCIS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142017.RAYDtlIINi1WAK2c5IqRzsPu4YzqrR7Oeh3Tkl92dqxFY130_provenance.
- NP142018.RAeAswPymU-bdiS6A8-I4GIJoAZccYv3KCvcXcNN7ERmU130_assertion description "[Expression of S100A4 protein was observed in 8 invasive carcinomas (80%), 5 high-grade dysphasia/carcinoma in situ cases (83%), and 0 low-grade dysplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142018.RAeAswPymU-bdiS6A8-I4GIJoAZccYv3KCvcXcNN7ERmU130_provenance.
- NP142019.RAex20Ab0K_Bc_5FqSwCgUM04l_OBhGicLyKaw4cDutdQ130_assertion description "[Claudin 4 is downregulated in lobular carcinoma in situ compated with normal breast epithelium and stroma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142019.RAex20Ab0K_Bc_5FqSwCgUM04l_OBhGicLyKaw4cDutdQ130_provenance.
- NP142021.RAVN6wcduDQzTMruy4YF0Na1Jvj1c4w0KtIteq5qJBSv0130_assertion description "[The goals of this study were to define the expression of the isoforms of MT 1, 2, 3 at both mRNA and protein levels, in normal prostate, benign prostatic hyperplasia (BPH) and malignant PC-3 cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142021.RAVN6wcduDQzTMruy4YF0Na1Jvj1c4w0KtIteq5qJBSv0130_provenance.
- NP142023.RASmaHOT0G8rUWKF8FvwC0oa2hwuh6tnmi5YGZBebZUeg130_assertion description "[ET-1 from the microvascular endothelium is inhibited by vascular endothelial growth factor and does not have a role as a growth factor in human benign prostatic hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142023.RASmaHOT0G8rUWKF8FvwC0oa2hwuh6tnmi5YGZBebZUeg130_provenance.
- NP142033.RAcuBjeq05X1llz21nZmhhDE-IgQaYnw3X800JvvXZdWo130_assertion description "[VEGF, FGF2, TGFB1, EGF and IGF1 have roles in the development of both prostate cancer and benign prostatic hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142033.RAcuBjeq05X1llz21nZmhhDE-IgQaYnw3X800JvvXZdWo130_provenance.
- NP142037.RATDY2maK2w4UmVwRruDwORM-RrnmRSCFs57zxjbdoaoA130_assertion description "[Down Regulation of BCL2 protein is associated with benign prostatic hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142037.RATDY2maK2w4UmVwRruDwORM-RrnmRSCFs57zxjbdoaoA130_provenance.
- NP142048.RAan3zKlehohmqBTfJgZTYz1kn38Sjt0BZgWa59qARHkQ130_assertion description "[CYP17 gene polymorphism may be associated with benign prostatic hyperplasia in the Turkish population ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142048.RAan3zKlehohmqBTfJgZTYz1kn38Sjt0BZgWa59qARHkQ130_provenance.
- NP142051.RAftZLZVEdS9ATE39x6X0q_lzwEMsWGcL6EFl3LAyOf6Q130_assertion description "[SRD5A2 gene codes the steroid 5-reductase type II, a critical mediator of androgen action, and the V89L and A49T polymorphisms of this gene may be associated risk of prostate cancer or benign prostatic hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142051.RAftZLZVEdS9ATE39x6X0q_lzwEMsWGcL6EFl3LAyOf6Q130_provenance.
- NP142055.RAXSJkF8IfsGh2hO1_yFqajq9qLbqxVWLBLylCuknLeVg130_assertion description "[thymidylate synthase and orotate phosphoribosyl transferase, but not dihydropyrimidine dehydrogenase, are more highly expressed in prostate cancer than in benign prostatic hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142055.RAXSJkF8IfsGh2hO1_yFqajq9qLbqxVWLBLylCuknLeVg130_provenance.
- NP142060.RAb3aXJ2NvMMr9TvhurUnWvc4Ps9j7ffgnzYKPURiV6RU130_assertion description "[PSA gene promoter variation may play a significant role in the development of prostate cancer and benign prostatic hyperplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142060.RAb3aXJ2NvMMr9TvhurUnWvc4Ps9j7ffgnzYKPURiV6RU130_provenance.
- NP142062.RAWguEVD_mE4Lq_CpzmXOF8CKlSWQ8mnR-tbNGwz0Xr7I130_assertion description "[PSA velocity did not predict benign prostatic hyperplasia progression in either alpha (1) -blocker treated patients or the watchful waiting (WW) group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142062.RAWguEVD_mE4Lq_CpzmXOF8CKlSWQ8mnR-tbNGwz0Xr7I130_provenance.
- NP142063.RAaKA3JRh50f65XNvZXaxSOTsGsO9tnxRyGmwmCdAq_uY130_assertion description "[increased alpha (2) -macroglobulin expression appears to be associated with benign prostatic hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142063.RAaKA3JRh50f65XNvZXaxSOTsGsO9tnxRyGmwmCdAq_uY130_provenance.
- NP142065.RAXeDzUvGDRrlixmYFI_dwqpgqXHOqYGPgnIzYj0hHZtg130_assertion description "[Leptin receptor did not reveal a definite difference between benign prostatic hyperplasia and prostate cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142065.RAXeDzUvGDRrlixmYFI_dwqpgqXHOqYGPgnIzYj0hHZtg130_provenance.
- NP142067.RAZMIcfCb_VsyQjPyiSs4kTLnbgM_rJunX8-LxVyD-Zn8130_assertion description "[Present, by immunocytochemistry, in normal prostate, prostatic hypertrophy and prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142067.RAZMIcfCb_VsyQjPyiSs4kTLnbgM_rJunX8-LxVyD-Zn8130_provenance.
- NP142068.RAU4LKbkt1x7mheYY1y3_kXeQamSX6J2A3Xd5dWORFk_8130_assertion description "[transforming growth factor-beta 1 gene polymorphism is associated with prostate cancer and benign prostatic hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142068.RAU4LKbkt1x7mheYY1y3_kXeQamSX6J2A3Xd5dWORFk_8130_provenance.
- NP142070.RAa2vy8PqkinBFNZSdRC6O9S-OaCqyL8rsFa18vaddzt0130_assertion description "[Candidate gene for benign prostatic hyperplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142070.RAa2vy8PqkinBFNZSdRC6O9S-OaCqyL8rsFa18vaddzt0130_provenance.
- NP142074.RAWvCEbiH5d8krevHY6Jugx3c06C55BmIXVfx2WKdMbbw130_assertion description "[High steady state levels of versican variants V0, V1, and V3 mRNA transcript and gene product are detected in the nodular tissues than in the non-nodular parenchyma of benign prostatic hyperplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142074.RAWvCEbiH5d8krevHY6Jugx3c06C55BmIXVfx2WKdMbbw130_provenance.
- NP142086.RAb0ggtYID5ADMBzzsRzbIhtsKFWAOjhQSerqLFtcf2A8130_assertion description "[No disease-specific CpG island methylation of SOCS1 is observed, but SOCS1 expression is raised in myeloproliferative disorder granulocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142086.RAb0ggtYID5ADMBzzsRzbIhtsKFWAOjhQSerqLFtcf2A8130_provenance.
- NP142096.RAapmvAFbyopUl0xNf50IRwZiaVdG28jUsO-9kRHsuCCs130_assertion description "[genetic predisposition to acquisition of different JAK2 mutations is inherited in families with myeloproliferative disorders ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142096.RAapmvAFbyopUl0xNf50IRwZiaVdG28jUsO-9kRHsuCCs130_provenance.
- NP142105.RAXep9NRGvCGMH2D9dsxu7w18lHox5Xv9FtvQ4UUUt-Rw130_assertion description "[results establish a role for JunB in normal erythropoiesis and indicate that JunB may play a major role in the development of JAK2 V617F myeloproliferative disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142105.RAXep9NRGvCGMH2D9dsxu7w18lHox5Xv9FtvQ4UUUt-Rw130_provenance.
- NP142111.RAdtZZjiNzGt_cj2Tl0raoZ9HQOOHTGBoaEJjZ2AXFkMM130_assertion description "[results establish a role for JunB in normal erythropoiesis and indicate that JunB may play a major role in the development of JAK2 V617F myeloproliferative disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142111.RAdtZZjiNzGt_cj2Tl0raoZ9HQOOHTGBoaEJjZ2AXFkMM130_provenance.
- NP142114.RAcSZtURk8Al7UOR3_tEj-iIYFe5gi2G0vRZgIz00IOAE130_assertion description "[4 types of JAK3 mutations were found in acute megakaryoblastic leukemia & transient myeloproliferative disorder patients, all in the pseudokinase domain or receptor-binding domain/is in the common-gamma-subunit-binding domain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142114.RAcSZtURk8Al7UOR3_tEj-iIYFe5gi2G0vRZgIz00IOAE130_provenance.
- NP142117.RAcUZszHRGIsH9u-9dcqpqbQIEgJPjuNVRc0fR6W9qssw130_assertion description "[A sensitive detection method for MPLW515L or MPLW515K mutation in chronic myeloproliferative disorders with locked nucleic acid-modified probes and real-time polymerase chain reaction is reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142117.RAcUZszHRGIsH9u-9dcqpqbQIEgJPjuNVRc0fR6W9qssw130_provenance.
- NP142120.RAVPZW5o-vEeEk95Ap05L9YAEaLTxQUru_3zGDkv8WWfo130_assertion description "[Characterization of the 4q21 breakpoint revealed PRKG2 as the likely gene partner to PDGFRB in myeloproliferative disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142120.RAVPZW5o-vEeEk95Ap05L9YAEaLTxQUru_3zGDkv8WWfo130_provenance.
- NP142121.RAfNjsRSPE26EGaybTR78xH56KCiothO9JzlKYuWyJX7I130_assertion description "[a novel function for Prv-1 as a signaling molecule in cytokine signaling cascades and may lead to a greater understanding of the mechanism of overexpression of Prv-1 in myeloproliferative disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142121.RAfNjsRSPE26EGaybTR78xH56KCiothO9JzlKYuWyJX7I130_provenance.
- NP142123.RATPboaA8j4VeZ3iTqNAuTT0a4pmsdEtkaq62zkxLqd-Q130_assertion description "[expression of GATA-1 with a defective N-terminal activation domain contributes to the expansion of transient myeloproliferative disorder blast cells and other genetic changes contribute to the development of acute megakaryocytic leukemia in Down syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142123.RATPboaA8j4VeZ3iTqNAuTT0a4pmsdEtkaq62zkxLqd-Q130_provenance.
- NP142131.RARrg46Yl3qX91yO-maFAFHFloukXFgKgBXst09T9THz0130_assertion description "[Increased expression of vascular endothelial growth factor is associated with myeloproliferative disorders ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142131.RARrg46Yl3qX91yO-maFAFHFloukXFgKgBXst09T9THz0130_provenance.
- NP142135.RAXsz-UZTSTGuPZabU1wqvZs_M5MnlQud2C_NYderbFbg130_assertion description "[The detailed angiogenic profile of VEGF in chronic myeloid leukemia may help in developing new therapeutic strategies for this myeloproliferative disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142135.RAXsz-UZTSTGuPZabU1wqvZs_M5MnlQud2C_NYderbFbg130_provenance.
- NP142138.RAd9coLKqGdV9_xEzltUC3g1rKvD5d48JjiE7oYW4xIzE130_assertion description "[point mutation are uncommon in patients with myeloproliferative disorders ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142138.RAd9coLKqGdV9_xEzltUC3g1rKvD5d48JjiE7oYW4xIzE130_provenance.
- NP142139.RASLIvyId7b6NRZ7NYYk6lptfJuugHGjv9R5Em0PJ-lVw130_assertion description "[b-FGF serum levels were significantly higher in patients with chronic myeloproliferative disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142139.RASLIvyId7b6NRZ7NYYk6lptfJuugHGjv9R5Em0PJ-lVw130_provenance.
- NP142148.RAQUZzoEUJ3GaZbVFd7a2omjCW733rO8sVLXMN4fMErKc130_assertion description "[Hematopoietin receptor superfamily/of cytokine-specific alpha chain and common beta chain for signaling/to differentiation and function of leukocytes/immunity and pathophysiology of immunologic diseases/. ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142148.RAQUZzoEUJ3GaZbVFd7a2omjCW733rO8sVLXMN4fMErKc130_provenance.
- NP142153.RAaqLy6WvOP-VwX-NsiVwgUdZbI9jFrvML9wC9E7l-ZNk130_assertion description "[Strong expression of SEMA6A is associated with langerhans cells of histiocytosis or dermatopathic lymphadenitis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142153.RAaqLy6WvOP-VwX-NsiVwgUdZbI9jFrvML9wC9E7l-ZNk130_provenance.
- NP142159.RAe7Du3zU6pNZdUe6Goq3Ci6vl5X3TEfMh7kQLIcjOhRI130_assertion description "[The cystathionine beta-synthase variant (insertion allele of CBS c.844 _ 845ins68) protects against CNS demyelination in X-linked adrenoleukodystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142159.RAe7Du3zU6pNZdUe6Goq3Ci6vl5X3TEfMh7kQLIcjOhRI130_provenance.
- NP142160.RAdh8YBwg4X_E8Vw6iU4ezTziyeX0qArlAFV4H2PmlI1k130_assertion description "[The splice mutation in 5'end of intron 5 leading to abnormal splice in exon 5 and exon 6 appears to be one of the causes of X-linked recessive adrenoleukodystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142160.RAdh8YBwg4X_E8Vw6iU4ezTziyeX0qArlAFV4H2PmlI1k130_provenance.
- NP142163.RAYaH7GzKnO3VWU8g8PW-m-W15l_nPsjaOZ6mw7IKMM_U130_assertion description "[Fifteen new mutations are described in Adrenoleukodystrophy patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142163.RAYaH7GzKnO3VWU8g8PW-m-W15l_nPsjaOZ6mw7IKMM_U130_provenance.
- NP142168.RAa6KxontIe-n_pe77l6qe4nyX-XzUlBvNIAI7Gze9ZZ8130_assertion description "[These findings are of particular importance for the attempt of pharmacological induction of ABCD2 as a possible therapeutic approach in X-linked adrenoleukodystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142168.RAa6KxontIe-n_pe77l6qe4nyX-XzUlBvNIAI7Gze9ZZ8130_provenance.
- NP142170.RAfPzBTFlPv9lqnAiK-Li1ZCVdz5Yzhy2Kqon2UFL7PMQ130_assertion description "[The limited tissue expression pattern and limited substrate specificity rule out a likely role for this enzyme in X-linked adrenoleukodystrophy pathology.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142170.RAfPzBTFlPv9lqnAiK-Li1ZCVdz5Yzhy2Kqon2UFL7PMQ130_provenance.
- NP142179.RAaSSIvVE2cWo2END6rdrqY5Q20gqFO_gN_UPN29nRqxs130_assertion description "[C3orf29 encodes hJUMPY, a phosphoinositide 3-phosphate phosphatase that acts on PtdIns3P and PtdIns (3, 5) P2/missense mutation disrupts the catalytic activity in a patient with centronuclear myopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142179.RAaSSIvVE2cWo2END6rdrqY5Q20gqFO_gN_UPN29nRqxs130_provenance.
- NP142180.RAQXu6P1aM3mQStWU2l5emGRP-jHOZSKPOk2iucAdhyO4130_assertion description "[This study suggests that the phenotypes of dynamin 2 related centronuclear myopathy and Charcot-Marie-Tooth disease overlap and that DNM2 mutations may alter cerebral function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142180.RAQXu6P1aM3mQStWU2l5emGRP-jHOZSKPOk2iucAdhyO4130_provenance.
- NP142184.RAf7xNeEQtvgbsDn3yESZZjkrlIF9d6dH7mgM6EHfOHJQ130_assertion description "[4 new variants were found in exons of the CACNA1A gene in sporadic hemiplegic migraine patients/does not seem that CACNA1A is a major gene in SHM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142184.RAf7xNeEQtvgbsDn3yESZZjkrlIF9d6dH7mgM6EHfOHJQ130_provenance.
- NP142192.RAYGElbcREpRcSgNUsR4hMWTMrL9WiFipp-aO06xGYYVc130_assertion description "[This article presents findings of higher NGF and BDNF levels correlated to increased glutamate levels in the CSF of both chronic migraine and fibromyalgia patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142192.RAYGElbcREpRcSgNUsR4hMWTMrL9WiFipp-aO06xGYYVc130_provenance.
- NP142195.RAaBtoX0IJXS4F3xTZXk0bUjg4BR55n3c3AxIvHenkqR8130_assertion description "[two novel ATP1A2 mutations that were identified in two Portuguese probands with hemiplegic migraine and interesting additional clinical features ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142195.RAaBtoX0IJXS4F3xTZXk0bUjg4BR55n3c3AxIvHenkqR8130_provenance.
- NP142197.RAfRQOxFN5DiDcB0uUNC7llQFz2fchLtD9rqeOgxdmikY130_assertion description "[D999H is a novel Hemiplegic Migraine, Familial ATP1A2 mutation in an Irish family.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142197.RAfRQOxFN5DiDcB0uUNC7llQFz2fchLtD9rqeOgxdmikY130_provenance.
- NP142209.RATtA-RAEqCwy9ncvlDIdMSBKg65loou_VkmIVXSg1OVc130_assertion description "[T666M CACNA1A mutation in early onset familial hemiplegic migraine type 1 with cerebellar atrophy and mental retardation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142209.RATtA-RAEqCwy9ncvlDIdMSBKg65loou_VkmIVXSg1OVc130_provenance.
- NP142211.RAdpQLdk4EATEp4Hoduz-cg_s4a5Xyr49vYQWJZxdtI80130_assertion description "[a modest protective effect of the MTHFR 677TT genotype on migraine with aura/increased risk for cardiovascular disease among migraineurs with aura was magnified for TT genotype carriers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142211.RAdpQLdk4EATEp4Hoduz-cg_s4a5Xyr49vYQWJZxdtI80130_provenance.
- NP142216.RAfgR1MiC9XiVE31qg9LqFxmMQiKGnQm3iqKKFdtgnk4Q130_assertion description "[5HTR2c Cys23Ser polymorphism may be associated with migraine with aura in a Japanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142216.RAfgR1MiC9XiVE31qg9LqFxmMQiKGnQm3iqKKFdtgnk4Q130_provenance.
- NP142219.RAUJSvSa9mbmK0EPX4ziACUsYetW3rrANAZf1ElVFUcIk130_assertion description "[missense mutations R689Q and M731T in familial hemiplegic migraine type 2 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142219.RAUJSvSa9mbmK0EPX4ziACUsYetW3rrANAZf1ElVFUcIk130_provenance.
- NP142221.RARUfu7rAgXhOYWUKHoLG2ZPtAVzy5Ia4W5Wx4d_H1W1w130_assertion description "[A less active short 5-HTT allele is involved in the polygenic etiology of migraine with aura.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142221.RARUfu7rAgXhOYWUKHoLG2ZPtAVzy5Ia4W5Wx4d_H1W1w130_provenance.
- NP142222.RAT0gUwlWD0WXhJjnoqWiSZ0RjSRY1seZMKle6sIaf6Xk130_assertion description "[Mutation of the familial hemiplegic migraine (type 3) SCN1A channel affects the gating properties of the channel, consistent with both hyperexitability and hypoexcitability.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142222.RAT0gUwlWD0WXhJjnoqWiSZ0RjSRY1seZMKle6sIaf6Xk130_provenance.
- NP142223.RAULH5SIpXu50UO5QBTyAqTqQFAXmg80ej-u3txnXjHLw130_assertion description "[The unique combination of a particularly slow inactivation of mutant S218L CaV2.1 channel during cortical spreading depression and a somewhat low threshold of channel activation might lead to delayed severe cerebral edema and coma after minor head trauma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142223.RAULH5SIpXu50UO5QBTyAqTqQFAXmg80ej-u3txnXjHLw130_provenance.
- NP142225.RAcHKNe0PRmwP7i5x5-JqArnGceWd5bX7G-K90gXu8Z6E130_assertion description "[epitope spreading between the Tr antigen and the MAZ-DCC complex offers a possible model of immune-mediated cerebellar disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142225.RAcHKNe0PRmwP7i5x5-JqArnGceWd5bX7G-K90gXu8Z6E130_provenance.
- NP142234.RAQ9dl_ttXcd_mWuu4VHm8RWJTX8UAtt6gV8o0NlbugHY130_assertion description "[SYNE1 is the first identified gene responsible for a recessively inherited pure cerebellar ataxia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142234.RAQ9dl_ttXcd_mWuu4VHm8RWJTX8UAtt6gV8o0NlbugHY130_provenance.
- NP142235.RAVSJ5JCivffNG2pIbcLmQMQMnnViTWVIGiSX6CggqPLw130_assertion description "[In mice, targeted disruption of Cacna2d2 led to growth retardation, reduced life span, ataxia, enhanced susceptibility to seizures, and cardiac abnormalities/may be involved in hereditary cerebellar ataxias and epileptic disorders in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142235.RAVSJ5JCivffNG2pIbcLmQMQMnnViTWVIGiSX6CggqPLw130_provenance.
- NP142238.RAetxDgyyns0VpQxwnLbqu3tLqoBv85IfWVUbUu4hF7hw130_assertion description "[Disease locus of 16q-autosomal dominant cerebellar ataxia was definitely confined to a 900-kb genomic region between the SNP04 and the -16C > T substitution in the puratrophin-1 gene in 16q22.1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142238.RAetxDgyyns0VpQxwnLbqu3tLqoBv85IfWVUbUu4hF7hw130_provenance.
- NP142239.RAZ0byxKCHTlEFKLKQYc0JYIyGtiNFItvTSaoUE2t_XXw130_assertion description "[Auto-antibodies to GAD67 and the more widely studied GAD65 homologue encoded by the GAD2 gene, are described in patients with Stiff-Person Syndrome (SPS), epilepsy, cerebellar ataxia and Batten disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142239.RAZ0byxKCHTlEFKLKQYc0JYIyGtiNFItvTSaoUE2t_XXw130_provenance.
- NP142241.RAUSg5SOeZCXdm9A_nafPal5OVB6bd9DiZ0PovrkqyCLY130_assertion description "[Trinucleotide repeat expansions of ataxin 7 may be involved in neurodegenerative diseases such as cerebellar ataxia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142241.RAUSg5SOeZCXdm9A_nafPal5OVB6bd9DiZ0PovrkqyCLY130_provenance.
- NP142247.RAYPOf29UBUBYO25n3lorddlHkr0zt1UIQgcY2e5QkAnA130_assertion description "[Case-control comparisons and the transmission disequilibrium test (TDT) both supported a coding SNP (cSNP) rs9934839 (R603R) in exon 9 as being close related to childhood absence epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142247.RAYPOf29UBUBYO25n3lorddlHkr0zt1UIQgcY2e5QkAnA130_provenance.
- NP142248.RAa1fJ-ZU5nE18dhKQ57XwXrRE3k8AkSP-MfkvUz4Vr0g130_assertion description "[Ca (v) 3.2 has a role in calcium influx during physiological activation and mutations may be causative in the propensity for seizures in patients with childhood absence epilepsy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142248.RAa1fJ-ZU5nE18dhKQ57XwXrRE3k8AkSP-MfkvUz4Vr0g130_provenance.
- NP142251.RAZMTjiYt1H-n9c0YFA2CkF6-VNEL6hzESwEca_ugBupw130_assertion description "[RCN2 is implicated in idiopathic absence epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142251.RAZMTjiYt1H-n9c0YFA2CkF6-VNEL6hzESwEca_ugBupw130_provenance.
- NP142255.RAWnoEHBCgiBf4l8mHDAA3FgDhYZiSV-KGTauw840hsi4130_assertion description "[Screening of the LGI4 coding region in BFIC and childhood absence epilepsy (CAE) revealed several frequent exonic polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142255.RAWnoEHBCgiBf4l8mHDAA3FgDhYZiSV-KGTauw840hsi4130_provenance.
- NP142261.RAcWRki4EdfAIl2fKleYABwEyIuHF6i6kfxlpWIveq5pA130_assertion description "[The VEGF expression and tumour angiogenesis are correlated with peritumoural brain edema.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142261.RAcWRki4EdfAIl2fKleYABwEyIuHF6i6kfxlpWIveq5pA130_provenance.
- NP142265.RAfo8rqdYnq5e5HTtUu_l5gA9RX9LU8JKPiNuZlStGQYo130_assertion description "[CRP has predictive value for CT-evidence of brain edema.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142265.RAfo8rqdYnq5e5HTtUu_l5gA9RX9LU8JKPiNuZlStGQYo130_provenance.
- NP142269.RAfXSb1L6e1kTiIlFF4ia0Xgd3-quatGU6uS0gxBKbuuU130_assertion description "[Intramolecular i-motif structure at acidic pH for progressive myoclonus epilepsy (EPM1) repeat d (CCCCGCCCCGCG) n.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142269.RAfXSb1L6e1kTiIlFF4ia0Xgd3-quatGU6uS0gxBKbuuU130_provenance.
- NP142272.RAdbNuiTxZ9LKAQg0aLKwV1_ecvIO5zfqhPrBlK415PKA130_assertion description "[The results of this study indicate that the clinical entity of Machado-Joseph disease can occur with 51 trinucleotide repeats, and that the clinical features of Machado-Joseph disease might cover a wider spectrum than previously believed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142272.RAdbNuiTxZ9LKAQg0aLKwV1_ecvIO5zfqhPrBlK415PKA130_provenance.
- NP142276.RAbir9Mpd40mhXo80vikVs_DgrU_G9ZNXkAhscA4TZVHU130_assertion description "[metabolic changes associated with transgenic mouse model of spinocerebellar ataxia 3 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142276.RAbir9Mpd40mhXo80vikVs_DgrU_G9ZNXkAhscA4TZVHU130_provenance.
- NP142284.RAWPb11QomamhfCENH-Stlc4p-XVKwMSqNQn606tbE8kU130_assertion description "[VCP-Atx-3 association is a potential target for therapeutic intervention and suggest that it might influence the progression of spinocerebellar ataxia type 3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142284.RAWPb11QomamhfCENH-Stlc4p-XVKwMSqNQn606tbE8kU130_provenance.
- NP142287.RAaIhehfn-litVaTKHaFEKXOZj9CEF53ZV7rg7rTCUhhQ130_assertion description "[linkage and association for three CAG triplet repeat markers (Spinocerebellar Ataxia Type 1, SCA1; Machado-Joseph Disease, MJD; Dentatorubro-pallidoluysian Atrophy, DRPLA) to assess their contribution to variation in cognitive ability ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142287.RAaIhehfn-litVaTKHaFEKXOZj9CEF53ZV7rg7rTCUhhQ130_provenance.
- NP142304.RAWWUuZK5S2wLYfccUYv3WFEegClLf80Y-_-f3Hfc1a6w130_assertion description "[The CCL19, CCL21/CCR7 chemokine system is expressed in inflamed muscles of polymyositis and may be involved in the pathomechanism of polymyositis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142304.RAWWUuZK5S2wLYfccUYv3WFEegClLf80Y-_-f3Hfc1a6w130_provenance.
- NP142307.RAbmVNkhrknMyPhdwcXdjv7TdUoxXG9-DwfeQ3p6w3qnk130_assertion description "[immunostaining for TG2 revealed substantial presence of this protein in single, damaged muscle fibers and a weak reaction in regenerating fibers appearing in polymyositis/dermatomyositis patients'specimens ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142307.RAbmVNkhrknMyPhdwcXdjv7TdUoxXG9-DwfeQ3p6w3qnk130_provenance.
- NP142309.RAWNq1amw08NWynfBJ3vxtluMTFIUSAzmluRTDCNtKz-U130_assertion description "[MMP7 immunoreactivity was present in only polymyositis not dermatomyositis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142309.RAWNq1amw08NWynfBJ3vxtluMTFIUSAzmluRTDCNtKz-U130_provenance.
- NP142313.RAaa2_8_tRcqFr7uisGepXlncGGjvBgZHmAHNz9Dx6heU130_assertion description "[Dermatomyositis and polymyositis are diseases characterized by the systemic overexpression of IFNalpha/beta-inducible genes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142313.RAaa2_8_tRcqFr7uisGepXlncGGjvBgZHmAHNz9Dx6heU130_provenance.
- NP142317.RAX663G3wvvScS4CFop0GZUpzPDtSusCcK9SB43I0g0mo130_assertion description "[The CCL19, CCL21/CCR7 chemokine system is expressed in inflamed muscles of polymyositis and may be involved in the pathomechanism of polymyositis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142317.RAX663G3wvvScS4CFop0GZUpzPDtSusCcK9SB43I0g0mo130_provenance.
- NP142325.RAfgLpxPvE8YGzcZq88hl8khDBjPWMEUyS5CEnlEgwizM130_assertion description "[Associations of tumor necrosis factor alpha and HLA polymorphisms with adult dermatomyositis: implications for a unique pathogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142325.RAfgLpxPvE8YGzcZq88hl8khDBjPWMEUyS5CEnlEgwizM130_provenance.
- NP142328.RAYl0-UtAbqZirOMor3qmuEIise4Sv6gti7Idue7SrVq8130_assertion description "[TNFalpha and IL-1 genetic polymorphisms contribute to the development of juvenile dermatomyositis and may also be indicators of disease severity ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142328.RAYl0-UtAbqZirOMor3qmuEIise4Sv6gti7Idue7SrVq8130_provenance.
- NP142333.RARIVilk06B9Q3iriFMyoLs9-E0WiAtnllR0esMR9QHR4130_assertion description "[increased production of IL-15 in muscle cells in polymyositis and dermatomyositis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142333.RARIVilk06B9Q3iriFMyoLs9-E0WiAtnllR0esMR9QHR4130_provenance.
- NP142341.RAUGEXnbDl0ZpFCU5rxRf5L3wb4XFXnW4igMTYejJ9Q-A130_assertion description "[the susceptibility gene for juvenile dermatomyositis either is HLA-DRB1*15021 or is present near the HLA-DRB1 locus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142341.RAUGEXnbDl0ZpFCU5rxRf5L3wb4XFXnW4igMTYejJ9Q-A130_provenance.
- NP142351.RAcErbkyW4RTAtx6aJihvRaegj5VDwwX1SIBqL-MPPL4c130_assertion description "[T-plastin has the potential to be a Sezary cell-specific marker valuable for diagnostic and treatment of Sezary syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142351.RAcErbkyW4RTAtx6aJihvRaegj5VDwwX1SIBqL-MPPL4c130_provenance.
- NP142355.RASq2l4j_SbXgztYydFqEQiBW-3Iq7RpAnp9h1Crsj4Qk130_assertion description "[experiments performed to investigate the survival, adhesion, and metalloproteases secretion indicate that CXCL13 combined with CCL19 and CCL21 mainly affects the chemotaxis of Sezary syndrome cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142355.RASq2l4j_SbXgztYydFqEQiBW-3Iq7RpAnp9h1Crsj4Qk130_provenance.
- NP142358.RAQuWn8UW6X3M2lGzAXgJ36so-OSF9mS_Ip8w5pIHENow130_assertion description "[A novel e8/a4 BCR/ABL fusion transcript is associated with a transformed Sezary syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142358.RAQuWn8UW6X3M2lGzAXgJ36so-OSF9mS_Ip8w5pIHENow130_provenance.
- NP142359.RAaDnuSvV0duTSl8Fsoab9BfsOU8nA-D1inHAc2-qccNQ130_assertion description "[ILT2 triggering on cutaneous T-cell lymphoma (CTCL) cells leads to the recruitment of SHP-1 and to the specific inhibition of CTCL malignant cell proliferation in Sezary syndrome induced by CD3/T-cell receptor/TCR) stimulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142359.RAaDnuSvV0duTSl8Fsoab9BfsOU8nA-D1inHAc2-qccNQ130_provenance.
- NP142361.RAcSo-lJlNdEcvmEQVFwlt6TXyTz9pUxDOZrZqL_aQ3GM130_assertion description "[CD158a and CD158b display a coactivatory function, involving the c-Jun NH2-terminal protein kinase signaling pathway, when expressed on malignant CD4+ T cells from a patient with Sezary syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142361.RAcSo-lJlNdEcvmEQVFwlt6TXyTz9pUxDOZrZqL_aQ3GM130_provenance.