Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP142367.RAWfq9FMh9ZJ0NvIeaWo3pRLgbLz1JKHTTd_T0HFEkO8s130_assertion description "[experiments performed to investigate the survival, adhesion, and metalloproteases secretion indicate that CXCL13 combined with CCL19 and CCL21 mainly affects the chemotaxis of Sezary syndrome cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142367.RAWfq9FMh9ZJ0NvIeaWo3pRLgbLz1JKHTTd_T0HFEkO8s130_provenance.
- NP142369.RAUODFxcg8Q2OqfjFrggyV8wjbtBxwxIQ0jruEmbgF5Og130_assertion description "[The tyrosine kinase receptor EphA4 and the potentially oncogenic transcription factor Twist were highly and selectively expressed in T cells of patients with Sezary Syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142369.RAUODFxcg8Q2OqfjFrggyV8wjbtBxwxIQ0jruEmbgF5Og130_provenance.
- NP142370.RASKCk3WI9ibwMj3sFedCNOfNBaSRvluczXUVwgAy-0z0130_assertion description "[experiments performed to investigate the survival, adhesion, and metalloproteases secretion indicate that CXCL13 combined with CCL19 and CCL21 mainly affects the chemotaxis of Sezary syndrome cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142370.RASKCk3WI9ibwMj3sFedCNOfNBaSRvluczXUVwgAy-0z0130_provenance.
- NP142371.RAZ8qZ0mR_LUemi7aSE1fi52od_4dqZTTJw59EMJBe0f4130_assertion description "[The genes GUS and PMM1 are recommended for normalization purposes in gene expression studies of liver tissue from patients with chronic hepatitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142371.RAZ8qZ0mR_LUemi7aSE1fi52od_4dqZTTJw59EMJBe0f4130_provenance.
- NP142387.RAeLw7IMtsObvqnlM-oMom0cwdqXRhDJ47gz4PNwioEnY130_assertion description "[the rearrangement of NFIB might be associated with deep-seated lipomas, such as retroperitoneal or gastro-intestinal lipomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142387.RAeLw7IMtsObvqnlM-oMom0cwdqXRhDJ47gz4PNwioEnY130_provenance.
- NP142390.RAQXz2j_oidpNmQlnykeyF2S3UQ0SGD3t3N-ozRV9zJVc130_assertion description "[Loss of chromosome 11 regions, including the deletion of PGL1 and PGL2 loci, may result in a severe phenotype, as exemplified by the development of paraganglioma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142390.RAQXz2j_oidpNmQlnykeyF2S3UQ0SGD3t3N-ozRV9zJVc130_provenance.
- NP142397.RASvkg9wGQjMrYuw15zniv9fvD4EKgl5AXErtqj-tZId8130_assertion description "[Paraganglioma after maternal transmission of a succinate dehydrogenase gene mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142397.RASvkg9wGQjMrYuw15zniv9fvD4EKgl5AXErtqj-tZId8130_provenance.
- NP142398.RAe-1SI-h2N-Q61Ga0HpsQXxbaEYmBMYJmpUy8tYJMDGY130_assertion description "[description of a large deletion in a complex II gene and confirmation of the role of SDHC in familial and sporadic paragangliomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142398.RAe-1SI-h2N-Q61Ga0HpsQXxbaEYmBMYJmpUy8tYJMDGY130_provenance.
- NP142399.RAVKmJ4-pSSEU4u1z5kJOxb4x_JgJz0QbHqpiz0ArwqUg130_assertion description "[Germline mutations of SDHC play a minor role in sporadic head and neck paraganglioma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142399.RAVKmJ4-pSSEU4u1z5kJOxb4x_JgJz0QbHqpiz0ArwqUg130_provenance.
- NP142402.RAWphplI-kr7IBmsYhBx8_M8ZoKAa8yp3fF2xF_FqPPK8130_assertion description "[familial gastrointestinal stromal tumors may be caused by mutations of the succinate dehydrogenase subunit genes SDHB, SDHC, and SDHD, and abdominal paragangliomas associated with gastrointestinal tumors may be caused uniquely by SDHC mutations ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142402.RAWphplI-kr7IBmsYhBx8_M8ZoKAa8yp3fF2xF_FqPPK8130_provenance.
- NP142405.RAcj_v8hrKunFhpVvxRDqIYjt2lf11lNRaFp-72hdqd78130_assertion description "[There is a pathogenic role of the succinate dehydrogenase B mutation (R46Q) in malignant paraganglioma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142405.RAcj_v8hrKunFhpVvxRDqIYjt2lf11lNRaFp-72hdqd78130_provenance.
- NP142408.RAUurwUGDw_cV9D9yJjVMfPcdE07gczehS5HhaXHTc4uU130_assertion description "[Mutations of the gene encoding succinate dehydrogenase subunit B predispose to malignant paraganglioma, but clinical expression of these tumors cannot be predicted by the genotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142408.RAUurwUGDw_cV9D9yJjVMfPcdE07gczehS5HhaXHTc4uU130_provenance.
- NP142417.RAVm-egMEyQs4GwMIlhi9op5TNQzWfm6uxRv-9d9H7Z10130_assertion description "[A novel point mutation in the VHL gene (406 T-- > G) was found in a patient with multiple recurrent chromaffin paragangliomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142417.RAVm-egMEyQs4GwMIlhi9op5TNQzWfm6uxRv-9d9H7Z10130_provenance.
- NP142418.RARWuyEoCv3H1sXk-iNtDIXir3Nu7V51lZDjWRIUnpdrk130_assertion description "[analysis of Von Hippel-Lindau mutations in Korean patients with von Hippel-Lindau disease, pheochromocytomas and paragangliomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142418.RARWuyEoCv3H1sXk-iNtDIXir3Nu7V51lZDjWRIUnpdrk130_provenance.
- NP142421.RATVq9sXVt-Zd5qNTbm_MlJ7ECqJ8U6OZYFF5ARBmzTBs130_assertion description "[p53 was slightly increased in inverted follicular keratoses compared with inflammed or non-inflamed seborrheic keratoses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142421.RATVq9sXVt-Zd5qNTbm_MlJ7ECqJ8U6OZYFF5ARBmzTBs130_provenance.
- NP142425.RAarwnJNiRA-rZjZd85coch1LpoMtmLTR4d2lOQz3vH5c130_assertion description "[Bcl-1 staining was similar in all benign keratoses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142425.RAarwnJNiRA-rZjZd85coch1LpoMtmLTR4d2lOQz3vH5c130_provenance.
- NP142431.RAXY3p6k4tFc91PNBdl5aHmF6SB4kUrQfJ07HOW9vhEAY130_assertion description "[In patients with pheochromocytoma or functional paraganglioma with an SDHB mutation, the tumors were larger, more frequently extra-adrenal, and malignant.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142431.RAXY3p6k4tFc91PNBdl5aHmF6SB4kUrQfJ07HOW9vhEAY130_provenance.
- NP142434.RActs-_xjt2MU8O10TcApuQisn21NJC2YhnNVaHaMLkeQ130_assertion description "[SDHB mutations, frequent in patients with malignant pheochromocytomas or paragangliomas, are associated with shorter survival ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142434.RActs-_xjt2MU8O10TcApuQisn21NJC2YhnNVaHaMLkeQ130_provenance.
- NP142435.RAbXzhwwSzOw2lF9_CnYoYZjItPsod-G4TVQyHIP5RTqQ130_assertion description "[survivin may represent a novel neuroendocrine marker for chromaffin cell tumors, survivin does not appear to reliably distinguish benign from malignant pheochromocytomas/paragangliomas and thus does not identify patients at risk of recurrent disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142435.RAbXzhwwSzOw2lF9_CnYoYZjItPsod-G4TVQyHIP5RTqQ130_provenance.
- NP142438.RARveglKxxJusx6Yn5vsK6H5gK0Q7XydeFimvVQ1bHQHw130_assertion description "[secretogranin II-derived peptide EM66 generated in human tumoral chromaffin tissue; significant difference in EM66 concentrations between benign and malignant pheochromocytomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142438.RARveglKxxJusx6Yn5vsK6H5gK0Q7XydeFimvVQ1bHQHw130_provenance.
- NP142439.RASaQk1gaL5D-B59OISHREF1BwHp3LYlQYa7wVl-R3ir4130_assertion description "[P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142439.RASaQk1gaL5D-B59OISHREF1BwHp3LYlQYa7wVl-R3ir4130_provenance.
- NP142454.RAfZ6ZFUE25vR9TL8t6BbwPetNonYZ7StEXGmolhjhAok130_assertion description "[Germline mutation on the SDHD gene was present in patients with pheochromocytoma or functional paraganglioma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142454.RAfZ6ZFUE25vR9TL8t6BbwPetNonYZ7StEXGmolhjhAok130_provenance.
- NP142457.RAYuYsf9WrGK2A63aDo0fycGZiFXm-CcRUvIoy2CV-89c130_assertion description "[Coexpression of Erythropoietin and Erythropoietin receptor was found in all five Hippel Lindau disease-associated pheochromocytomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142457.RAYuYsf9WrGK2A63aDo0fycGZiFXm-CcRUvIoy2CV-89c130_provenance.
- NP142461.RAXg6K7QVatPgtpJorOB9vm59LVZasJMfHKofLGLhd6W8130_assertion description "[These data indicates that the expression of AT1 receptors is altered in adrenal cancer and in pheochromocytomas/expression of AT2 receptors, in turn, may be connected with the process of tumoral neo-angiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142461.RAXg6K7QVatPgtpJorOB9vm59LVZasJMfHKofLGLhd6W8130_provenance.
- NP142476.RAbOWcJieRCGEmdXKD60m0Cp8ThgIVRkyCn3r9lY_DbEQ130_assertion description "[Data support that EGFR and HER-2/neu play an important role in cell cycle control in ductal carcinoma in situ.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142476.RAbOWcJieRCGEmdXKD60m0Cp8ThgIVRkyCn3r9lY_DbEQ130_provenance.
- NP142482.RAdXBPFoJKrYIvFFbr2ZjwXW1MPFMf3kFMfEqk3L0Z6_8130_assertion description "[There was a highly significant positive association between p27 (KIP-1) and estrogen receptor/progesterone receptor (ER/PR) status and with p27 (KIP-1) and cyclin D1 expression in patients with DCIS ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142482.RAdXBPFoJKrYIvFFbr2ZjwXW1MPFMf3kFMfEqk3L0Z6_8130_provenance.
- NP142485.RAV3zhkxrYXURMxXJpjz4qz6ueg2HheEqLsnvhco0Pjm4130_assertion description "[Dpc4 may have a role in invasiveness of intraductal carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142485.RAV3zhkxrYXURMxXJpjz4qz6ueg2HheEqLsnvhco0Pjm4130_provenance.
- NP142491.RATNdctrbuQtWo0tByD94Ik-W3Dvt_TAvaqnG-IfPrp4s130_assertion description "[The combined immunohistochemical and genetic data of carcinoma ex pleomorphic adenoma and intraductal carcinoma showed genetic or morphological evidence of dysfunctional p53, indicating that this is an early event in malignant transformation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142491.RATNdctrbuQtWo0tByD94Ik-W3Dvt_TAvaqnG-IfPrp4s130_provenance.
- NP142493.RAfGsI7dsOrH7-zEYxkBobZDMP0-svGdia6qfdSW1Ghpw130_assertion description "[Intraductal trastuzumab treatment may be effective in the management of ductal carcinoma in situ of the breast with HER-2 overexpression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142493.RAfGsI7dsOrH7-zEYxkBobZDMP0-svGdia6qfdSW1Ghpw130_provenance.
- NP142499.RAdTMOWOfCkEeAYmwvFhYAnkilWxDkKqp3O7DD7SBDY7s130_assertion description "[MUC1 splice variant expression is different in pure DCIS compared to DCIS with adjacent invasive cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142499.RAdTMOWOfCkEeAYmwvFhYAnkilWxDkKqp3O7DD7SBDY7s130_provenance.
- NP142510.RAVWBuciYfIiL-q1Va8dIAbrZrjF7uccm_dMNOaQriPKM130_assertion description "[examined the effect of the dyskeratosis congenita mutations on the structure and stability of human telomerase RNA pseudoknot and CR7 domains ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142510.RAVWBuciYfIiL-q1Va8dIAbrZrjF7uccm_dMNOaQriPKM130_provenance.
- NP142517.RAUc7IjGa46RJlCK2GgF6mY3QP4GyLrROv4CCk74zOiC0130_assertion description "[Dyskeratosis congenita -related mutations of hTR C408G and Delta378-451 severely impair pre-RNP assembly.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142517.RAUc7IjGa46RJlCK2GgF6mY3QP4GyLrROv4CCk74zOiC0130_provenance.
- NP142519.RATtV6WzSF9Wu3Y3f0NwemyzLJXI1feWH-iViHa9fq-ok130_assertion description "[In a large series, TINF2 mutations account for approximately 11% of all patients with dyskeratosis congenita.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142519.RATtV6WzSF9Wu3Y3f0NwemyzLJXI1feWH-iViHa9fq-ok130_provenance.
- NP142523.RAagkU3HGmQcuH13aZ_G71wtPF5lxiSdGofWak-xLlBBE130_assertion description "[TERT mutations have a role in autosomal dominant dyskeratosis congenita ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142523.RAagkU3HGmQcuH13aZ_G71wtPF5lxiSdGofWak-xLlBBE130_provenance.
- NP142527.RAStQmVaxlOqR2zQY6Cxoqs-iZE3mikQoqe7NdVu8nvlk130_assertion description "[mutations in the telomerase complex and their connections with dyskeratosis congenita and bone marrow failures [review]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142527.RAStQmVaxlOqR2zQY6Cxoqs-iZE3mikQoqe7NdVu8nvlk130_provenance.
- NP142530.RAZn6tsERa_vRc_AcOADoXKfmBP4uqlJVZ33-rZ-I7f5M130_assertion description "[specific defect in IRES (internal ribosome entry site) -dependent translation in X-linked dyskeratosis congenita cells; defect results in impaired translation of mRNAs containing IRES elements, including those encoding p27Kip1), Bcl-xL and XIAP ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142530.RAZn6tsERa_vRc_AcOADoXKfmBP4uqlJVZ33-rZ-I7f5M130_provenance.
- NP142532.RARgSsrh7z6CkJ4IPnldwTU0UCWWfVrfN4k_kYb03yAKo130_assertion description "[These data demonstrate that this domain of dyskerin plays an important role in telomerase maintenance following cell insults such as cisplatin treatment, and in telomerase-defective cells in patients with X-linked dyskeratosis congenita.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142532.RARgSsrh7z6CkJ4IPnldwTU0UCWWfVrfN4k_kYb03yAKo130_provenance.
- NP142533.RAe2g23CTb530y4Ehovez3yfcsa0qrRh34g-ALvio6LDg130_assertion description "[These data demonstrate that this domain of dyskerin plays an important role in telomerase maintenance following cell insults such as cisplatin treatment, and in telomerase-defective cells in patients with X-linked dyskeratosis congenita.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142533.RAe2g23CTb530y4Ehovez3yfcsa0qrRh34g-ALvio6LDg130_provenance.
- NP142542.RAWWRVgMu4HAGFGtml41JbyIUZghrFHqC50YvAl4cPKww130_assertion description "[In a Brazilian populaiton with beta Thalassemia, the beta 0 codon 39 nonsense mutation was the most frequent alteration (50.9%), followed by beta+ IVSI 110 G > A (18.1%), beta 0 IVSI 1 G > A (12.9%), beta+ IVSI 6 T > C (9.5%), and other rare mutations (8.6% ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142542.RAWWRVgMu4HAGFGtml41JbyIUZghrFHqC50YvAl4cPKww130_provenance.
- NP142543.RAeP5HIXjHBaeF3XY32QVbrJiho9p0lXjOBKchq4Q02U4130_assertion description "[two new beta thalassemia mutations in betea globin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142543.RAeP5HIXjHBaeF3XY32QVbrJiho9p0lXjOBKchq4Q02U4130_provenance.
- NP142544.RAYwu-jneOE4DMyeaJ-ulAjJ7PeBopiUL7AzNKK1Fs2RI130_assertion description "[Screening beta thalassemia trait individuals from Northern Ireland has detected 2 Mediterranean mutations; the previously reported IVS-II-850 (G -- > A) mutation; and 2 novel mutations, initiation codon A -- > C and 109 delG ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142544.RAYwu-jneOE4DMyeaJ-ulAjJ7PeBopiUL7AzNKK1Fs2RI130_provenance.
- NP142549.RAYZwacPJoujOpq9sPZFGjrwL8F2bMgXYCTdZHkfrhYAY130_assertion description "[In alpha-thalassemia, alpha/beta-globin mRNA ratio correlated with the number of functional alpha-globin genes present, whereas in beta-thalassemia, the ratio provided a good indicator of disease severity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142549.RAYZwacPJoujOpq9sPZFGjrwL8F2bMgXYCTdZHkfrhYAY130_provenance.
- NP142550.RAWEsE1lcb8R8C0JIc5-lMIung1AuvMk82EhYl5DPex0k130_assertion description "[In alpha-thalassemia, alpha/beta-globin mRNA ratio correlated with the number of functional alpha-globin genes present, whereas in beta-thalassemia, the ratio provided a good indicator of disease severity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142550.RAWEsE1lcb8R8C0JIc5-lMIung1AuvMk82EhYl5DPex0k130_provenance.
- NP142551.RAagjAb69Arv5ubUwaqzaATKlUQhd5PmNfFUMkCd8P28U130_assertion description "[severe anemia with low Hb concentration might up regulate hTERT expression of bone marrow CD34+ cells and serum erythropoietin levels in patients with beta-thalassemia major ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142551.RAagjAb69Arv5ubUwaqzaATKlUQhd5PmNfFUMkCd8P28U130_provenance.
- NP142554.RAcYmKhBxP667bFT1V-joAK89D8vIzLVbbs78cCBJwJNA130_assertion description "[In beta-thalassemia patients, a significant correlation exists between plasma chitotriosidase & ferritin & with mean number of transfusions per year/levels in children and increased levels in only some adults may reflect macrophage iron overload.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142554.RAcYmKhBxP667bFT1V-joAK89D8vIzLVbbs78cCBJwJNA130_provenance.
- NP142556.RAUt6XjMPjc76dQa1VltVWi2eW3fTF5ILUu4MYrRyw3Cg130_assertion description "[Quantitative analysis of erythrocyte membrane proteins revealed increase in alpha-spectrin from patients with homozygous and heterozygous forms of beta-thalassemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142556.RAUt6XjMPjc76dQa1VltVWi2eW3fTF5ILUu4MYrRyw3Cg130_provenance.
- NP142570.RAcDGj2-CCoFqluoaqCXx1dCbl43FPPu_7B_aS8Rn6P2U130_assertion description "[Quantitative analysis of erythrocyte membrane proteins revealed decrease in palladin from patients with homozygous and heterozygous forms of beta-thalassemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142570.RAcDGj2-CCoFqluoaqCXx1dCbl43FPPu_7B_aS8Rn6P2U130_provenance.
- NP142576.RASpdA0HCoqexXHdz32EvmLtl0qETf-JJLdE8sLcd002s130_assertion description "[CDKN1A expression increased with increasing grade in meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142576.RASpdA0HCoqexXHdz32EvmLtl0qETf-JJLdE8sLcd002s130_provenance.
- NP142579.RAfU66LQ4K6XU_glEic7MUPBOkfzkG1YZJaok3Q5d4qZ8130_assertion description "[These findings suggest that expression of Cx26 and Cx43 might be related to the differentiation of the arachnoid villi and meningiomas, and exhibit the different origin of various subtypes of meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142579.RAfU66LQ4K6XU_glEic7MUPBOkfzkG1YZJaok3Q5d4qZ8130_provenance.
- NP142581.RAdF5xeml2EKz73b7dLWsZ8UgPDRuwjAIgccH37I8oRqk130_assertion description "[EPB41 gene expression was unchanged in all analyzed meningiomas/suggests that involvement of the EPB41 gene (4.1R protein) in meningioma pathogenesis should be reconsidered.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142581.RAdF5xeml2EKz73b7dLWsZ8UgPDRuwjAIgccH37I8oRqk130_provenance.
- NP142599.RAYgv0IaEd67YfYLrx8L2EDqjYpWX8N24tmntB_y87HLM130_assertion description "[transitional and fibroblastic meningiomas harbor significantly more NF2 mutations than meningothelial meningiomas, indicating molecular subsets of these tumors ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142599.RAYgv0IaEd67YfYLrx8L2EDqjYpWX8N24tmntB_y87HLM130_provenance.
- NP142601.RAfOuf3q62cvgL9SnVF5I-fUcRJKDJ0PPJKcZqBG0WVY4130_assertion description "[These studies implicate the DAL-1/4.1B locus in sporadic meningiomas less commonly than reported previously, and suggest that it is a progression rather than an initiation locus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142601.RAfOuf3q62cvgL9SnVF5I-fUcRJKDJ0PPJKcZqBG0WVY4130_provenance.
- NP142609.RATjX9aGwarqALGjezqVUsvwaah7NDymeRcau8paLk5LQ130_assertion description "[study found associations of risk haplotypes and protective haplotypes in p53 for glioblastoma and in ATM for meningioma; study provides new data that could add to our understanding of brain tumour susceptibility ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142609.RATjX9aGwarqALGjezqVUsvwaah7NDymeRcau8paLk5LQ130_provenance.
- NP142615.RAVG67tjzS-FRHLWR_hrU_zQKo-U7EPcEFEaCOqjj8FsM130_assertion description "[tissue factor has a role in affecting proliferative ability in meningioma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142615.RAVG67tjzS-FRHLWR_hrU_zQKo-U7EPcEFEaCOqjj8FsM130_provenance.
- NP142616.RAbrwbSYF5bXFr_jh5g27cRAU5S0qYDjaPJzsTMiMCjlw130_assertion description "[Integrin-alpha 3 sub-unit participates the process of regulating growth of meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142616.RAbrwbSYF5bXFr_jh5g27cRAU5S0qYDjaPJzsTMiMCjlw130_provenance.
- NP142619.RAcPHLmzwcpehngQdV1FWe6OLC_S39Wr1AhVGBl4vCYzI130_assertion description "[Data show that PR expression is higher in the meningiomas positive for GnRH-R and a significantly higher proportion of tumors from male patients exhibit positive immunoreactivity for GnRH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142619.RAcPHLmzwcpehngQdV1FWe6OLC_S39Wr1AhVGBl4vCYzI130_provenance.
- NP142621.RAbc2-ECJkIOzdYfOtyMu7HD8RGhsaZQwIb1LHXErKflA130_assertion description "[analysis of CASP8 D302H role in risk of meningioma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142621.RAbc2-ECJkIOzdYfOtyMu7HD8RGhsaZQwIb1LHXErKflA130_provenance.
- NP142624.RARdUxRl7JmtLiDkcZDUU3K5RCvkFvgSxsejqMLewyDHM130_assertion description "[Losses of INK4a/INK4b gene products play a big role in meningioma formation & malignant progression/of p16/p15 and pl4ARF pendent pathways possibly along with telomerase activation might be critical for meningioma immortalization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142624.RARdUxRl7JmtLiDkcZDUU3K5RCvkFvgSxsejqMLewyDHM130_provenance.
- NP142626.RAcirUjVIInw_YAYX6PbkpavRGVqFWtjTVdhsPnmwE6tE130_assertion description "[HuR is involved in the upregulation of VEGF-A expression in human meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142626.RAcirUjVIInw_YAYX6PbkpavRGVqFWtjTVdhsPnmwE6tE130_provenance.
- NP142629.RAbE-NKSSoqv79ntUipNREqKVLvj5y525l13cBQNTq4Uw130_assertion description "[MIB-1 (Ki-67) positive tumor cells were maximally aggregated at the periphery of an excised specimen and can provide better information about the disease biological nature in benign meningiomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142629.RAbE-NKSSoqv79ntUipNREqKVLvj5y525l13cBQNTq4Uw130_provenance.
- NP142632.RATIzrmPrmaIizORWaWFKVYS-TgOAcHGB7gC10nos13U4130_assertion description "[The RAD54L polymorphism (2290C/T) can be used as a genetic marker inside the consensus deletion region at 1p32 in human meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142632.RATIzrmPrmaIizORWaWFKVYS-TgOAcHGB7gC10nos13U4130_provenance.
- NP142636.RAcWoqfO07ivSkUGLiD46jAhcP2VY3toRUghKgi-Yt5nY130_assertion description "[These data shed more light on the molecular biology of meningioma cells and suggest that survivin and proteins of the RB pathway could play a determinant role in the development and the treatment of meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142636.RAcWoqfO07ivSkUGLiD46jAhcP2VY3toRUghKgi-Yt5nY130_provenance.
- NP142650.RAed-JET7BShpIdNmrEfprC4HkmhZurohAd8vPDJW9uU4130_assertion description "[study found associations of risk haplotypes and protective haplotypes in p53 for glioblastoma and in ATM for meningioma; study provides new data that could add to our understanding of brain tumour susceptibility ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142650.RAed-JET7BShpIdNmrEfprC4HkmhZurohAd8vPDJW9uU4130_provenance.
- NP142654.RAdi7JlHrm4ZFL2fSjPgaRCsUAhe8-77g-leFVbRrYjaM130_assertion description "[Germline mutation of the VHL gene and loss of heterozygosity on the VHL gene locus in 3p were detected in a meningioma in VHL disease associated with multiple cerebellar hemangioblastomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142654.RAdi7JlHrm4ZFL2fSjPgaRCsUAhe8-77g-leFVbRrYjaM130_provenance.
- NP142658.RAWFX7AiB1qf6vcU5q_4HnOmN-1319HbZf0DdCD0yxduc130_assertion description "[cathepsin and inhibitor expression was not different between central and peripheral meningioma tissue or between histological subtypes of meningiomas with the exception of cathepsin L, the level of which was significantly lower in transitional meningiomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142658.RAWFX7AiB1qf6vcU5q_4HnOmN-1319HbZf0DdCD0yxduc130_provenance.
- NP142660.RAQ69L75zT-HQznVS3GgUFnBI7fRkfQb3Vu2w0Su2GvPk130_assertion description "[HLA alleles plays an important role in the development of central nervous system meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142660.RAQ69L75zT-HQznVS3GgUFnBI7fRkfQb3Vu2w0Su2GvPk130_provenance.
- NP142666.RAWw9u5Q1NSHEmRJU2Hpb0HuiaVH_X8cKDIlR5HtAd6EQ130_assertion description "[Conclude that the Ki-67 and p53 labeling indices are useful additional tools in discriminating atypical from benign or anaplastic meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142666.RAWw9u5Q1NSHEmRJU2Hpb0HuiaVH_X8cKDIlR5HtAd6EQ130_provenance.
- NP142670.RAc62t6oax6UD5l94Sw5la01wage0YUfMyG1uadraJ5sE130_assertion description "[Protein and mRNA levels of stefin B (p = 0.007), but not cystatin C, were significantly lower in atypical compared with benign meningiomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142670.RAc62t6oax6UD5l94Sw5la01wage0YUfMyG1uadraJ5sE130_provenance.
- NP142673.RAcooVGtD_WVxpB1CcOLAJ6FWbIggy4wKIMadEuXWKS10130_assertion description "[The results of this study suggest that genetic variants of methionine metabolism are associated with meningioma formation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142673.RAcooVGtD_WVxpB1CcOLAJ6FWbIggy4wKIMadEuXWKS10130_provenance.
- NP142680.RAUq8dN3CfCGy7s4JPfSWhKmk11CgX0AU8jNFZpobnolk130_assertion description "[Up-regulation of Ets-1 expression was observed in atypical and anaplastic meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142680.RAUq8dN3CfCGy7s4JPfSWhKmk11CgX0AU8jNFZpobnolk130_provenance.
- NP142687.RAWqLUdlwZD6h72WUMvf6c24RNBdnE6-IeHsswF2emTzg130_assertion description "[CDK4, MDM2, SAS and GLI genes are amplified in leiomyosarcoma, alveolar and embryonal rhabdomyosarcoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142687.RAWqLUdlwZD6h72WUMvf6c24RNBdnE6-IeHsswF2emTzg130_provenance.
- NP142691.RAfb50EKHy-WTCk_xW6sxA0TYc_7pf55nHvP4-KfTLuyA130_assertion description "[in the RD embryonal rhabdomyosarcoma cell line, expression of wild-type PAX7 is downregulated by PAX3-FKHR ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142691.RAfb50EKHy-WTCk_xW6sxA0TYc_7pf55nHvP4-KfTLuyA130_provenance.
- NP142692.RAbd1TJ_-pzZwT8xV_E1unMzvFF1ZdRP0JMR347EUGGz0130_assertion description "[PAX 7-FKHR fusion transcripts were positive in 2/7 of alveolar rhabdomyosarcoma patients, and were negative in embryonal rhabdomyosarcoma and Control tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142692.RAbd1TJ_-pzZwT8xV_E1unMzvFF1ZdRP0JMR347EUGGz0130_provenance.
- NP142693.RAfpVvSxieHSjQFbWUsjFRC0YFLMkE-du9FOtjG9cTIHQ130_assertion description "[YB-1 nuclear expression support the concept that alveolar and embryonal rhabdomyosarcomas are molecular biologically distinct neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142693.RAfpVvSxieHSjQFbWUsjFRC0YFLMkE-du9FOtjG9cTIHQ130_provenance.
- NP142698.RAeiZ1XPziHXKdTmjJBp4fJygnjtsgle0TJYEun39xXgo130_assertion description "[in the RD embryonal rhabdomyosarcoma cell line, PAX3-FKHR upregulates expression of the gene encoding the chemokine receptor CXCR4 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142698.RAeiZ1XPziHXKdTmjJBp4fJygnjtsgle0TJYEun39xXgo130_provenance.
- NP142701.RAc0_QBHcx9Sx2rMLnlC-_OAhCk3ao3FHDtpo-2O86bJc130_assertion description "[CDK4, MDM2, SAS and GLI genes are amplified in leiomyosarcoma, alveolar and embryonal rhabdomyosarcoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142701.RAc0_QBHcx9Sx2rMLnlC-_OAhCk3ao3FHDtpo-2O86bJc130_provenance.
- NP142725.RAWAOJHH9jjCXdXEjM-2Hb7xoL8qE483oI-AEPOR5hGlE130_assertion description "[expression of estrogen receptor alpha and estrogen receptor beta were studied in leiomyomas and homologous myometrium from women in the proliferative phase of the menstrual cycle and from women treated with a gonadotropin-releasing hormone analogue ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142725.RAWAOJHH9jjCXdXEjM-2Hb7xoL8qE483oI-AEPOR5hGlE130_provenance.
- NP142728.RAbQf9doEiZe6pXSzi0c2WnzOlxMJttJZ6EM-DjdLuqrc130_assertion description "[high-activity Catechol-O-methyltransferase (COMT) Val/Val genotype is associated with increased risk of Uterine leiomyomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142728.RAbQf9doEiZe6pXSzi0c2WnzOlxMJttJZ6EM-DjdLuqrc130_provenance.
- NP142729.RAWZCrNAJx1ocGFuCvKs_9iJRPGrm2OXG9Tnm3Vlf2dQI130_assertion description "[catechol-O-methyltransferase polymorphism is a risk factor for the development of large uterine fibroids in Brazilian women suffering from fibroids.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142729.RAWZCrNAJx1ocGFuCvKs_9iJRPGrm2OXG9Tnm3Vlf2dQI130_provenance.
- NP142735.RAbExcAwRthvEYmNUmxOKP9wG-N9YNA_0Or1-bsQ2kbX4130_assertion description "[a new mutation in the fumarate hydratase gene may have a role in cerebral cavernomas in a family with multiple cutaneous and uterine leiomyomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142735.RAbExcAwRthvEYmNUmxOKP9wG-N9YNA_0Or1-bsQ2kbX4130_provenance.
- NP142737.RAUc82-O5LnCEl-9DTgTPUT2kTSYJ2U8PkrJB5VW2sT7U130_assertion description "[In human uterine leiomyomas, FGFR1 were also overexpressed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142737.RAUc82-O5LnCEl-9DTgTPUT2kTSYJ2U8PkrJB5VW2sT7U130_provenance.
- NP142741.RAdGnJq3H2qUcY89A6MbtXq_kyHA6-IQCZi0IDx_J2BzY130_assertion description "[C/EBPbeta, which binds to multiple cis-regulatory elements in promoter I.3/II, is a key factor in the transcriptional complex controlling aromatase expression in uterine leiomyoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142741.RAdGnJq3H2qUcY89A6MbtXq_kyHA6-IQCZi0IDx_J2BzY130_provenance.
- NP142748.RAel0e8F1q26WQ7ZMcAFIoAib5dnR-sE7lrThHPg0oh6E130_assertion description "[Downregulated by cetrorelix in cultured leiomyoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142748.RAel0e8F1q26WQ7ZMcAFIoAib5dnR-sE7lrThHPg0oh6E130_provenance.
- NP142755.RAVQbIcrBUOwCeSbvvXIIdczwSjsWIkkGUNrHd25G68FQ130_assertion description "[PCNA expression induces apoptosis by up-regulating cleaved caspase-3 and poly adp ribose polymerase expression and down-regulating Bcl-2 protein expression in leiomyoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142755.RAVQbIcrBUOwCeSbvvXIIdczwSjsWIkkGUNrHd25G68FQ130_provenance.
- NP142757.RAd4ArN05OrH5gmGZxMBMR6W5bKq-PZMUTKGdQHNPFrds130_assertion description "[progesterone via progesterone receptor interacts with the bcl-2 promoter to induce its expression in leiomyoma tissue ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142757.RAd4ArN05OrH5gmGZxMBMR6W5bKq-PZMUTKGdQHNPFrds130_provenance.
- NP142760.RAZ6k-F4XqkdDgzB4MKRILu3mBgZPX_F7I-zkFYnjOXI0130_assertion description "[The female reproductive tract expresses AHR and ARNT mRNA, and changes in expression at target sites in conditions such as endometriosis and uterine leiomyomas suggest a potential role for these factors in the pathogenesis of these conditions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142760.RAZ6k-F4XqkdDgzB4MKRILu3mBgZPX_F7I-zkFYnjOXI0130_provenance.
- NP142767.RAVnfuB15Z8DBLpuzGJTkgCeH58iAJL7D5ust94xytmY4130_assertion description "[Shrinkage in uterine volume induced by GnRH analogs seems to be related to reduction in IGF-I-R levels// IGF-I-R system might affect leiomyoma growth/of GnRH analogs on uterine leiomyomas might be related to the effects on IGF-I-R expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142767.RAVnfuB15Z8DBLpuzGJTkgCeH58iAJL7D5ust94xytmY4130_provenance.
- NP142770.RAR7txuNgGlR__FJAZ07zyvz6cvVhaLfYG37y-bQD6r1U130_assertion description "[Data suggest that angiotensin I-converting enzyme gene polymorphisms are strongly related to the occurrence of endometriosis and moderately related to the occurrence of leiomyoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142770.RAR7txuNgGlR__FJAZ07zyvz6cvVhaLfYG37y-bQD6r1U130_provenance.
- NP142781.RARToxGtIeW-hj1libbf7iEG7VKAoxtBOskl5cNryKo0I130_assertion description "[The A allele and AA genotype of CCND1 G870A polymorphism have a significant association with an increased risk of the uterine leiomyoma in obese Korean women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142781.RARToxGtIeW-hj1libbf7iEG7VKAoxtBOskl5cNryKo0I130_provenance.
- NP142784.RASyYc0-T3MCNu9_HasZC5Srq7KGMd2dyITy-gWjcrrkU130_assertion description "[present findings suggest that CYP17A1, CYP19, and androgen receptor polymorphisms are unlikely to be associated with an increased risk of uterine leiomyomas in Brazilian women ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142784.RASyYc0-T3MCNu9_HasZC5Srq7KGMd2dyITy-gWjcrrkU130_provenance.
- NP142786.RAcXvr96InId7f8BApg7KUq0fpwuL4lPtUJfB7aC9bkw8130_assertion description "[In human uterine leiomyomas, GRB2 were also overexpressed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142786.RAcXvr96InId7f8BApg7KUq0fpwuL4lPtUJfB7aC9bkw8130_provenance.
- NP142791.RAT86qiJaNPscAlmVMzL_9LNiEFAQQwz5zFX5n8C5s3Ds130_assertion description "[AR trinucleotide polymorphism is associated with leiomyoma susceptibility ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142791.RAT86qiJaNPscAlmVMzL_9LNiEFAQQwz5zFX5n8C5s3Ds130_provenance.
- NP142793.RARzMJBnU_afLbeWP6PCqCw3tbT7Foj4BUpr5CRgKC7J4130_assertion description "[In human uterine leiomyomas, ERBB2 were also overexpressed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142793.RARzMJBnU_afLbeWP6PCqCw3tbT7Foj4BUpr5CRgKC7J4130_provenance.
- NP142798.RAVG5taLy5F01WZqsLQvRSz6Sc_1GaUkFTLV3BCA05nO0130_assertion description "[Pituitary tumor-transforming gene-1 is up-regulated in human uterine leiomyomas and that the positive feedback loop between PTTG-1 and basic fibroblast growth factor may be pivotal in the growth of leiomyoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142798.RAVG5taLy5F01WZqsLQvRSz6Sc_1GaUkFTLV3BCA05nO0130_provenance.
- NP142802.RAYZt03tmy5mP6QMtVY6zcuS4pTnK9YFGYIdAm9QvTcEg130_assertion description "[Thrombospondin-1 was consistently underexpressed in both the edge and center of uterine fibroids.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142802.RAYZt03tmy5mP6QMtVY6zcuS4pTnK9YFGYIdAm9QvTcEg130_provenance.
- NP142804.RATwScFf2kGnFGFad8-bEu8l_PZtrjNenetP2fJQlhBfg130_assertion description "[telomerase activity in needle biopsy samples is a useful diagnostic marker to distinguish uterine sarcoma from leiomyoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142804.RATwScFf2kGnFGFad8-bEu8l_PZtrjNenetP2fJQlhBfg130_provenance.
- NP142806.RAQeoqXYT72q6FBN0GfGeBL-qKm-NtapMK3HEVGp8FL9U130_assertion description "[ER beta may also be involved in the IGF-I signaling pathway in leiomyoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142806.RAQeoqXYT72q6FBN0GfGeBL-qKm-NtapMK3HEVGp8FL9U130_provenance.
- NP142807.RAejIMZkCTy5O_BOEIYUoR81B5e4-01iA3fKFA9a3cXAE130_assertion description "[The female reproductive tract expresses AHR and ARNT mRNA, and changes in expression at target sites in conditions such as endometriosis and uterine leiomyomas suggest a potential role for these factors in the pathogenesis of these conditions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142807.RAejIMZkCTy5O_BOEIYUoR81B5e4-01iA3fKFA9a3cXAE130_provenance.
- NP142821.RAek0eQG04mZZyzbXRQFSru4Ds2cvwnC4pf2poTmf_130130_assertion description "[The c-Myc oncogene expression was very low in normal and cancer tissues but highly increased in papillomatosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142821.RAek0eQG04mZZyzbXRQFSru4Ds2cvwnC4pf2poTmf_130130_provenance.
- NP142837.RAWfd-KaOhmYCq00fXbBYVd3YRdoe--ViYEcZB5kVrUGc130_assertion description "[Abnormality of the p53 pathway was detected in cervix cancer and in CINs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP142837.RAWfd-KaOhmYCq00fXbBYVd3YRdoe--ViYEcZB5kVrUGc130_provenance.