Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP143273.RAeR4Sb3cRhg4pqPgTHdunetvOv93wwpHg0QZYLEQFK9k130_assertion description "[TGF-beta1, TGF-beta2 and TGF-beta3 isoforms are produced by chondrosarcomas and could have a potential role as autocrine growth stimulators in these neoplasms ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143273.RAeR4Sb3cRhg4pqPgTHdunetvOv93wwpHg0QZYLEQFK9k130_provenance.
- NP143276.RAT8ULkiPxYAn2OBXzjydsSB6wqjHicx0SryV9_5mONS4130_assertion description "[TNF-alpha activates a distinct set of genes in chondrosarcoma cells, and gene expression in these cells is regulated by groups of genes related in part by their function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143276.RAT8ULkiPxYAn2OBXzjydsSB6wqjHicx0SryV9_5mONS4130_provenance.
- NP143278.RAZs30r-hBKfwk51nIn8dtOERb3UJ_jTajUQ5DOdSWDp0130_assertion description "[Inhibition of human chondrosarcoma cell growth via apoptosis by peroxisome proliferator-activated receptor-gamma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143278.RAZs30r-hBKfwk51nIn8dtOERb3UJ_jTajUQ5DOdSWDp0130_provenance.
- NP143286.RAYxA8ErtY5WtkypLzSxrTbFwb4Iqga4TkA52swSpbnzo130_assertion description "[The PDGF expression, as a marker of angiogenesis, was evaluated in myomas obtained after surgery.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143286.RAYxA8ErtY5WtkypLzSxrTbFwb4Iqga4TkA52swSpbnzo130_provenance.
- NP143292.RAcApdTGsItMX0VSvOpg73oVqEKgcMFRJw8sIKwk61H64130_assertion description "[Beta-catenin may have an important role in the development of malignancy and in the determination of biological features of keratoacanthoma and squamous cell carcinoma of the skin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143292.RAcApdTGsItMX0VSvOpg73oVqEKgcMFRJw8sIKwk61H64130_provenance.
- NP143299.RAZHeDEi_BH4vLT6AnicgArd-nXn1y8-FXgs3GuDGvEV0130_assertion description "[By comparing the expression of p53, cyclin D1, p16, hTERT, and TSP-1 in spontaneously regressing keratoacanthoma and squamous cell carcinoma, the changes in the expression of these proteins to specific stages of skin carcinogenesis, is defined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143299.RAZHeDEi_BH4vLT6AnicgArd-nXn1y8-FXgs3GuDGvEV0130_provenance.
- NP143303.RAb9uni-fK4e6Dc6djaekocEH3QT4d_y4cgfluA_PG6-8130_assertion description "[complex interaction between signaling from the CXCR4 receptor on acute lymphoblastic leukemia cells with those initiated by IL-7 & IL-3, suggesting CXCL12 may facilitate ALL proliferation by enhancing cytokine-signaling pathways in responsive cases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143303.RAb9uni-fK4e6Dc6djaekocEH3QT4d_y4cgfluA_PG6-8130_provenance.
- NP143304.RAUYaddeIhbv7_M8cK0D8K6Z_qpevQI-31J_hKedOsQ2w130_assertion description "[Patients who had a combined BM relapse had lower IL-8 and CXCR4 expression than those who had an isolated BM relapse om chldhood acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143304.RAUYaddeIhbv7_M8cK0D8K6Z_qpevQI-31J_hKedOsQ2w130_provenance.
- NP143305.RARasFvu-Wa025CT3wS6YeusLyiS_NbzAtoOQDnDhLrcs130_assertion description "[there was no evidence of an accumulation of cyclin A-positive childhood acute lymphoblastic leukemia cells that are unable to progress through the S phase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143305.RARasFvu-Wa025CT3wS6YeusLyiS_NbzAtoOQDnDhLrcs130_provenance.
- NP143308.RAd6dHtj524S6GI9Tq9je9VSlvie334HN4OW0VbNvD3Gg130_assertion description "[High interleukin-15 expression is associated with childhood acute lymphoblastic leukemia with involvement of the Central Nervous System ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143308.RAd6dHtj524S6GI9Tq9je9VSlvie334HN4OW0VbNvD3Gg130_provenance.
- NP143310.RASFRzbQUUU_fYvBGU8So-l9oMMGWi9s9Lk05GVY_Ykro130_assertion description "[TEL/AML1 fusion gene may have a role in childhood acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143310.RASFRzbQUUU_fYvBGU8So-l9oMMGWi9s9Lk05GVY_Ykro130_provenance.
- NP143315.RAe2zNIOqSwMBzuisil7rXqX-JCFqjVWfMScvTxQJ5YJk130_assertion description "[c-MET is associated with FAS and when activated enhances drug-induced apoptosis in pediatric B acute lymphoblastic leukemia with TEL-AML1 translocation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143315.RAe2zNIOqSwMBzuisil7rXqX-JCFqjVWfMScvTxQJ5YJk130_provenance.
- NP143317.RAYdzJ0FcyzG-ueioHSmuNu8SWg3WVBDmoMlyeQYX2NVE130_assertion description "[The TCR gene rearrangements in childhood B-lineage acute lymphoblastic leukemia was associated with expression of AML1 chimeric oncogene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143317.RAYdzJ0FcyzG-ueioHSmuNu8SWg3WVBDmoMlyeQYX2NVE130_provenance.
- NP143321.RAagE0GoWv-SjIYp3n-tRvu3fBAuIe2T8_JZ7mm8xDNmE130_assertion description "[TEL-AML1 may have a role in T-cell receptor gene rearrangements in pediatric acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143321.RAagE0GoWv-SjIYp3n-tRvu3fBAuIe2T8_JZ7mm8xDNmE130_provenance.
- NP143326.RAQdmPA-kcnFQxV0j_q98ypvXuc0pQQwySnotW5K0wKXY130_assertion description "[After CD40-activation, acute lymphocytic leukemia cells released substantial amounts of interleukin-10 (IL-10) but were unable to produce bioactive IL-12.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143326.RAQdmPA-kcnFQxV0j_q98ypvXuc0pQQwySnotW5K0wKXY130_provenance.
- NP143331.RAbaz1J85KTaEYprRPNgAxLhat4Tih_WcPTTZChqsGQ_g130_assertion description "[high expression of MRP1 was associated with the MDR phenotype in both acute myeloid leukemia and acute lymphoblastic leukemia patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143331.RAbaz1J85KTaEYprRPNgAxLhat4Tih_WcPTTZChqsGQ_g130_provenance.
- NP143333.RAX6yexRMUK90Llk2tmPS963a30-c135W9Un8lyICtgOk130_assertion description "[Translocations in Hox11L2 locus is associated with T-cell acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143333.RAX6yexRMUK90Llk2tmPS963a30-c135W9Un8lyICtgOk130_provenance.
- NP143334.RAT020Yx-Yv_UgPUJ4h18vQajQj8iD766KkEOFPkMk6Xs130_assertion description "[In T-cell acute lymphoblastic leukemia, alternative t (5; 14) (q35; q32.2) forms effect dysregulation of either TLX3 or NKX2-5 homeobox genes at 5q35 by juxtaposition with 14q32.2 breakpoints dispersed across the BCL11B downstream genomic desert.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143334.RAT020Yx-Yv_UgPUJ4h18vQajQj8iD766KkEOFPkMk6Xs130_provenance.
- NP143336.RAcVJ3WkDzM8MfW8xbouIf_HIZOxAE--JvoQIaSVv4nd8130_assertion description "[Aberrant HOX11L2 expression is associated with thymic adult T-cell acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143336.RAcVJ3WkDzM8MfW8xbouIf_HIZOxAE--JvoQIaSVv4nd8130_provenance.
- NP143337.RAabB6D2UyohV-Qw9HTz0D1C-ZK1mFbXKo6EKaLI99jzk130_assertion description "[high basal MMP-9 activity is associated with tumoral syndrome in childhood acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143337.RAabB6D2UyohV-Qw9HTz0D1C-ZK1mFbXKo6EKaLI99jzk130_provenance.
- NP143345.RAYh7PDl2eR1EFJP_C_1yiAQA-hTijTNpcX3r8sO4NJsQ130_assertion description "[MTHFR 677C/T and RFC1 80G/A polymorphisms may serve as predictors of toxicity during maintenance chemotherapy in childhood acute lymphoblastic leukemia or lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143345.RAYh7PDl2eR1EFJP_C_1yiAQA-hTijTNpcX3r8sO4NJsQ130_provenance.
- NP143348.RATYVXAQO33hX4tTWL5t3u88ufuwbJKYRG6EunVE6zc1I130_assertion description "[( MTHFR) T677 variant had a significantly lower frequency of weeks with high-grade hematologic and liver toxicity during consolidation and maintenance treatment of acute lymphocytic leukemia in children.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143348.RATYVXAQO33hX4tTWL5t3u88ufuwbJKYRG6EunVE6zc1I130_provenance.
- NP143357.RAd8SU6Z83R7bgIyfdd9bsbKAd8CIpx6xuLaA048ILpvc130_assertion description "[c-MET is associated with FAS and when activated enhances drug-induced apoptosis in pediatric B acute lymphoblastic leukemia with TEL-AML1 translocation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143357.RAd8SU6Z83R7bgIyfdd9bsbKAd8CIpx6xuLaA048ILpvc130_provenance.
- NP143366.RAbsVOpynKIk8RkUYKgkWXD84BUwsp_CD0Zd_W-VHPlII130_assertion description "[Cellular resistance to TRAIL could be developed through phosphorylation (activation) of Akt and phosphorylation (inactivation) of PTEN in acute lymphoblastic leukemia cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143366.RAbsVOpynKIk8RkUYKgkWXD84BUwsp_CD0Zd_W-VHPlII130_provenance.
- NP143367.RAePLWjXYmslrXDkUP2HAJJegEvOvCmXxzg0K4v166eIM130_assertion description "[FXIII-A is a sufficiently sensitive marker in differentiating myeloblasts and monoblasts and is suitable for identifying leukemia-associated phenotypes in acute lymphoblastic leukemia.[ review]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143367.RAePLWjXYmslrXDkUP2HAJJegEvOvCmXxzg0K4v166eIM130_provenance.
- NP143368.RAVzkBIIu8s3_gqqJAWZEftPc__8Vsa8JUQEpC33AWHhk130_assertion description "[This gene is fused to MLL in childhood acute lymphoblastic leukemia with t (2; 11) (q11; q23).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143368.RAVzkBIIu8s3_gqqJAWZEftPc__8Vsa8JUQEpC33AWHhk130_provenance.
- NP143370.RAczIeKS45Vkr0TsY1cpH7Hvp-QZ2A3MGbSMYz5Lsrpow130_assertion description "[Mutation in KRAS is associated with childhood acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143370.RAczIeKS45Vkr0TsY1cpH7Hvp-QZ2A3MGbSMYz5Lsrpow130_provenance.
- NP143376.RAVlZENKqSOmYQX03QHMVsi2X786YlpCOqOFDo8LUa4HE130_assertion description "[TPMT genotype has a substantial impact on minimal residual disease after administration of mercaptopurine in the early course of childhood ALL, most likely through modulation of mercaptopurine dose intensity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143376.RAVlZENKqSOmYQX03QHMVsi2X786YlpCOqOFDo8LUa4HE130_provenance.
- NP143382.RAWrHumgKYMlkhvYEwoSNlyKtHmB0yyHJcNz6Er12Fi3s130_assertion description "[CXCL12 may have a role in leukaemic cell proliferation and survival during childhood ALL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143382.RAWrHumgKYMlkhvYEwoSNlyKtHmB0yyHJcNz6Er12Fi3s130_provenance.
- NP143386.RATd1fdZLpcSlAJg1pxdYnh8i0oNMNe9aq2NzMEOmg7ko130_assertion description "[MDR1 expression in childhood ALL is an independent adverse prognostic factor on outcome, and could be a useful biological marker of response ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143386.RATd1fdZLpcSlAJg1pxdYnh8i0oNMNe9aq2NzMEOmg7ko130_provenance.
- NP143388.RAUUb0t-Zr1afWjSRNJq2IWPi0oFnrAqswONSvcTU5jzA130_assertion description "[upregulation of important elements of apoptosis at mRNA level of FLICE in acute lymphoblastic leukemia cells after CD40 ligation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143388.RAUUb0t-Zr1afWjSRNJq2IWPi0oFnrAqswONSvcTU5jzA130_provenance.
- NP143390.RASo5cW2QYyYM2eE6E8F6rBuYYMBavVrVM0OnlsasrDPk130_assertion description "[Deletion analysis of p16 (INKa) and p15 (INKb) in relapsed childhood acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143390.RASo5cW2QYyYM2eE6E8F6rBuYYMBavVrVM0OnlsasrDPk130_provenance.
- NP143393.RAfOoK-pq2Nmi7_Gxe-_OZMhQrg-hCS6lN7C9e1A3hQZI130_assertion description "[There is a protective effect from prednisone poor response in patients with the IL-10 G/G genotype/association of the risk of relapse and IL-10 genotype was found/genotype might influence prednisone response in patients with childhood ALL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143393.RAfOoK-pq2Nmi7_Gxe-_OZMhQrg-hCS6lN7C9e1A3hQZI130_provenance.
- NP143412.RAeICb8aURpwMGpWyCPHtQ_CZid5Pta2x_Z81UmrCwyE4130_assertion description "[Variable Ikaros isoform expression is associated with precursor-B acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143412.RAeICb8aURpwMGpWyCPHtQ_CZid5Pta2x_Z81UmrCwyE4130_provenance.
- NP143413.RAUsM8MTAEhB5kiJiCKMgM0uBzUsurzUEVyhd_AtXN_cc130_assertion description "[both aberrant splicing and genomic deletion leading to different non-DNA-binding Ikaros cDNA transcripts are common features of Philadelphia chromosome-positive acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143413.RAUsM8MTAEhB5kiJiCKMgM0uBzUsurzUEVyhd_AtXN_cc130_provenance.
- NP143418.RAdfhfHJQY0J0RCNd-xq_s57v-IbHSuBy_WWGZBuR77gw130_assertion description "[BCL-2 overexpression was noted in 29.4% cases of T-cell lymphoblastic lymphoma cases but was not correlated with higher rate of relapse ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143418.RAdfhfHJQY0J0RCNd-xq_s57v-IbHSuBy_WWGZBuR77gw130_provenance.
- NP143419.RAQehG7ACZ7VKHFx-s2IKv2DRHItYa53UbkGi0nc9iY0w130_assertion description "[up-regulation of bcl-2 has a role in preferential survival of acute lymphoblastic leukemia cells at 33 degrees C ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143419.RAQehG7ACZ7VKHFx-s2IKv2DRHItYa53UbkGi0nc9iY0w130_provenance.
- NP143420.RAVhgGjDAz686oZdTcjnkXe12COc9zBLd-dq5wCeG__AA130_assertion description "[Escape of human T-cell acute lymphoblastic leukemia cells from dormancy is associated with increased Notch3 signaling in tumor cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143420.RAVhgGjDAz686oZdTcjnkXe12COc9zBLd-dq5wCeG__AA130_provenance.
- NP143421.RAcILYQXT7-vVqJipOw0Z1A7ZDAbh9jJ5y_aDlJTz76xw130_assertion description "[dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143421.RAcILYQXT7-vVqJipOw0Z1A7ZDAbh9jJ5y_aDlJTz76xw130_provenance.
- NP143425.RAZi6pLd4MFH98sCa206eigtZdlUO-PbkSeEHoF2Ijicc130_assertion description "[Higher ABCG2 expression is associated with T-lineage acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143425.RAZi6pLd4MFH98sCa206eigtZdlUO-PbkSeEHoF2Ijicc130_provenance.
- NP143434.RAUtYWClNubKadl-CtuuMoc_lalpws7IAW_H-BxfOU0R8130_assertion description "[These findings suggest the novel possible role of SP in blasts proliferation in childhood ALL of common (CD10) origin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143434.RAUtYWClNubKadl-CtuuMoc_lalpws7IAW_H-BxfOU0R8130_provenance.
- NP143440.RAf4xuDIqrmNWVeaUVzgEFjMdnTwRXQoQ-h7NLxG3O06o130_assertion description "[Gene rearrangement and genetic translocations observed in acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143440.RAf4xuDIqrmNWVeaUVzgEFjMdnTwRXQoQ-h7NLxG3O06o130_provenance.
- NP143441.RARzu9WquALeAxGTmNGNW5lq4_TEmUBjRGPYjwZuen4_A130_assertion description "[The patients with immunophenotype of Pre-B-acute lymphoblastic leukemia were found to carry: MLL/AF4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143441.RARzu9WquALeAxGTmNGNW5lq4_TEmUBjRGPYjwZuen4_A130_provenance.
- NP143442.RARsKMiz9_qI_dA45dBR9JC6xYDPRO4hjtE8T6JUfxToU130_assertion description "[There is fusion of an AF4-related gene, LAF4, to this gene in childhood acute lymphoblastic leukemia with t (2; 11) (q11; q23).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143442.RARsKMiz9_qI_dA45dBR9JC6xYDPRO4hjtE8T6JUfxToU130_provenance.
- NP143443.RAXNAbCuxi2aX__QG7zD7xUia-dUfIvoWyUYBW2iS-zfA130_assertion description "[The TCR gene rearrangements in childhood B-lineage acute lymphoblastic leukemia was associated with expression of MLL chimeric oncogene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143443.RAXNAbCuxi2aX__QG7zD7xUia-dUfIvoWyUYBW2iS-zfA130_provenance.
- NP143446.RAYXABqkV9rE9owdGV5Qo-tSoEVpU6g15_AlqqK3B30Zw130_assertion description "[Mutated in acute myelocytic leukemia combined with acute lymphocytic leukemia in a case report.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143446.RAYXABqkV9rE9owdGV5Qo-tSoEVpU6g15_AlqqK3B30Zw130_provenance.
- NP143448.RAUscmDZ_W-sU09Q2hc8VcPBjPNA3BzgwQeUXOuw-I92w130_assertion description "[the incidence of deletions from the der (9) in childhood acute lymphoblastic leukemia is at least as high as that reported for chronic myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143448.RAUscmDZ_W-sU09Q2hc8VcPBjPNA3BzgwQeUXOuw-I92w130_provenance.
- NP143450.RARaptqhW3Hbx6VvOTdsQfZanhP6mtkJ9RNmOayizeCuM130_assertion description "[The Aberrant expression of Rb Genes were determined in bone marrow samples of children with de novo B-lineage (n = 170) and T-lineage (n = 25) acute lymphoblastic leukemia (ALL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143450.RARaptqhW3Hbx6VvOTdsQfZanhP6mtkJ9RNmOayizeCuM130_provenance.
- NP143454.RAUDNGzv5eZUwMY9Dih77iKhonEJivIl4VLYNv7EKwL1s130_assertion description "[The HOXA11 gene cluster is in T-cell malignancies resulting in deregulated HOXA gene expression and is in keeping with a previous report suggesting HOXA deregulation in MLL-rearranged T cell lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143454.RAUDNGzv5eZUwMY9Dih77iKhonEJivIl4VLYNv7EKwL1s130_provenance.
- NP143456.RAbVupRU0GT9KXzM8jz5cF-QUzof00zg9v1j_QBekxils130_assertion description "[RNA interference decreases capacity of mesenchymal stem cells to protect acute lymphoblastic leukemia cells from asparaginase, whereas enforced ASNS expression conferred enhanced protection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143456.RAbVupRU0GT9KXzM8jz5cF-QUzof00zg9v1j_QBekxils130_provenance.
- NP143462.RAdhGwCdW3PfnP0UaKX3PgnloUKAdP-TwRLoZWmbFazCY130_assertion description "[data indicate that the CYP1A1*2A genotype contributes significantly to susceptibility to adult acute lymphoblastic leukemia in a sample of the Mexican population ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143462.RAdhGwCdW3PfnP0UaKX3PgnloUKAdP-TwRLoZWmbFazCY130_provenance.
- NP143464.RATKIHnCOHr5eg3HciOmDqE6DVotwpg20xv9dmQ4AJR3I130_assertion description "[The patients with immunophenotype of Pre-B-acute lymphoblastic leukemia were found to carry: MLL/AFX.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143464.RATKIHnCOHr5eg3HciOmDqE6DVotwpg20xv9dmQ4AJR3I130_provenance.
- NP143467.RAZqZU56Y6CaY8RemcJ8K0lulQ0-3nF7abGElQte6QQ80130_assertion description "[loss of heterozygosity in the MLL gene in childhood ALL ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143467.RAZqZU56Y6CaY8RemcJ8K0lulQ0-3nF7abGElQte6QQ80130_provenance.
- NP143474.RAQcj9olcmguoXath_ydBe5Gj37vSvqMsACLA3fz6yb4A130_assertion description "[A B-cell lineage acute lymphoblastic leukemia patient with a t (6; 14) chromosomal translocation that deregulated ID4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143474.RAQcj9olcmguoXath_ydBe5Gj37vSvqMsACLA3fz6yb4A130_provenance.
- NP143479.RAXI4hmdfCMFiGMDFfzF80hI9Cr6SLz22fyJxGwk_QFLU130_assertion description "[The RT-PCR of TSGA10 expression may help in detection of residual clonal cells leading to early diagnosis and better prognostic qualification of the acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143479.RAXI4hmdfCMFiGMDFfzF80hI9Cr6SLz22fyJxGwk_QFLU130_provenance.
- NP143483.RAVQzGMZKKQYlnEcMNGYbx5Crfy5cJ7-5iVBpnSQkGCsE130_assertion description "[Frequently mutated in high hyperdiploid childhood acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143483.RAVQzGMZKKQYlnEcMNGYbx5Crfy5cJ7-5iVBpnSQkGCsE130_provenance.
- NP143484.RAfYvDmpt0DNIbCt__FPVhuUjiTpBTZ9eGgkAfkTZp5lM130_assertion description "[Overexpression of orphan receptor tyrosine kinase Ror1 is associated with acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143484.RAfYvDmpt0DNIbCt__FPVhuUjiTpBTZ9eGgkAfkTZp5lM130_provenance.
- NP143486.RAY102DrPFSz6Hhv48QRj4J5aD-oT41ZvNly5dGjHVQLU130_assertion description "[VEGFR-1/-3 co-expression is associated with high hemoglobin level in childhood acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143486.RAY102DrPFSz6Hhv48QRj4J5aD-oT41ZvNly5dGjHVQLU130_provenance.
- NP143496.RAYoreYAvmlJpDl38kPQf8jLM4eaol9OJJ7dC6ZZ8jZUg130_assertion description "[Activating mutations in the FLT3 RTK gene were found in each of 3 CD117/KIT (+) cases that were analyzed, but not in 52 other adult T-acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143496.RAYoreYAvmlJpDl38kPQf8jLM4eaol9OJJ7dC6ZZ8jZUg130_provenance.
- NP143507.RAfD4rLvwOLWJewTdtWUBECUnBfrYjpZe1UMmpcixXX0E130_assertion description "[Protein kinase A, not Epac, suppresses hedgehog activity and regulates glucocorticoid sensitivity in acute lymphoblastic leukemia cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143507.RAfD4rLvwOLWJewTdtWUBECUnBfrYjpZe1UMmpcixXX0E130_provenance.
- NP143510.RATKIyks9O4p4FVMeVVce_jNjQPsiQ83l4HT8zKXCM8aM130_assertion description "[A role for ARF in human Philadelphia chromosome-positive lymphoblastic leukemia progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143510.RATKIyks9O4p4FVMeVVce_jNjQPsiQ83l4HT8zKXCM8aM130_provenance.
- NP143512.RAbD_qoL9BljibOGjiZA11p5dPdFtcgKxrAaOeMraPbjE130_assertion description "[analysis of TS polymorphisms in childhood acute lymphoblastic leukemia patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143512.RAbD_qoL9BljibOGjiZA11p5dPdFtcgKxrAaOeMraPbjE130_provenance.
- NP143513.RAdadaO1ZIk_aMtv1SXYBE7Vy64Dpwtywo42VJszJU7wM130_assertion description "[Duplication of MYB is an oncogenic event and we suggest that MYB could be a therapeutic target in human T cell acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143513.RAdadaO1ZIk_aMtv1SXYBE7Vy64Dpwtywo42VJszJU7wM130_provenance.
- NP143525.RAR3mEDqcJ58ZQ5OX0dYp88L96mhaGvZLFrGNACOrnRxY130_assertion description "[The Aberrant expression of p53 Genes were determined in bone marrow samples of children with de novo B-lineage (n = 170) and T-lineage (n = 25) acute lymphoblastic leukemia (ALL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143525.RAR3mEDqcJ58ZQ5OX0dYp88L96mhaGvZLFrGNACOrnRxY130_provenance.
- NP143526.RAQvnx2k5LFBCLqVPemydMQpV-8DZNULSvFP717ktUbIU130_assertion description "[Analysis of TOP2A gene amplification and gene overexpression in newly diagnosed childhood ALL cases and inverse correlation with glucocorticoid resistance ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143526.RAQvnx2k5LFBCLqVPemydMQpV-8DZNULSvFP717ktUbIU130_provenance.
- NP143530.RAVHUmDV-06QwhXGfpBge3ho81w-zCvQBeODdfOW3cbeg130_assertion description "[the TBL1XR1 gene was significantly under-expressed in acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143530.RAVHUmDV-06QwhXGfpBge3ho81w-zCvQBeODdfOW3cbeg130_provenance.
- NP143531.RAUE2utPzCFEFVq6rnaHutHqNXpN1n7C9ebciR7tSj_Lg130_assertion description "[Patients with immunophenotype of Pre-B-acute lymphoblastic leukemia were found to carry: TLS/ERG.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143531.RAUE2utPzCFEFVq6rnaHutHqNXpN1n7C9ebciR7tSj_Lg130_provenance.
- NP143534.RAXP5Pl5_23UB99n_j_oSxJF7xFqTQ5PJtSIuIb9g0xE8130_assertion description "[the tumor clones in childhood acute lymphoblastic leukemia do not express the leptin receptor ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143534.RAXP5Pl5_23UB99n_j_oSxJF7xFqTQ5PJtSIuIb9g0xE8130_provenance.
- NP143537.RAZMHLypMKNwkDgM_6n7dy1kwSCoUFAyWhkTboEN1v9lg130_assertion description "[A91V is a novel and frequent predisposing factor for childhood ALL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143537.RAZMHLypMKNwkDgM_6n7dy1kwSCoUFAyWhkTboEN1v9lg130_provenance.
- NP143539.RASPDcjhY2LT8H6ItgMsw48rmLPRkw2heLNpMZzQP2ax0130_assertion description "[DNA ligase IV gene polymorphisms might have a role in acute lymphoblastic leukemia in children ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143539.RASPDcjhY2LT8H6ItgMsw48rmLPRkw2heLNpMZzQP2ax0130_provenance.
- NP143540.RARVgBcJfbG7H4ShKJQlcutb7IgYMWb-DqPNJvp1kCXBw130_assertion description "[In T-cell acute lymphoblastic leukemia, alternative t (5; 14) (q35; q32.2) forms effect dysregulation of either TLX3 or NKX2-5 homeobox genes at 5q35 by juxtaposition with 14q32.2 breakpoints dispersed across the BCL11B downstream genomic desert.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143540.RARVgBcJfbG7H4ShKJQlcutb7IgYMWb-DqPNJvp1kCXBw130_provenance.
- NP143546.RAYWBAm5enlBFpAop1M116f0-5wa7IH8hytxADp0JkuLY130_assertion description "[A high GYPC gene expression is associated with an unfavorable outcome, in contrast, a high TRIP3 gene expression is associated with a favorable outcome in childhood ALL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143546.RAYWBAm5enlBFpAop1M116f0-5wa7IH8hytxADp0JkuLY130_provenance.
- NP143552.RAe1FajsHogKum07ZC88IrDCXkedpyPC44C23T2hYYQhE130_assertion description "[frequency of the mutation in the NBS1 carriers was indeed increased in patients with acute lymphoblastic leukemia and non-Hodgkin lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143552.RAe1FajsHogKum07ZC88IrDCXkedpyPC44C23T2hYYQhE130_provenance.
- NP143554.RASHyu3Vs_e1Ae9pXdzHuOpgBvCWojKaGn1tzI4snLBpU130_assertion description "[identified homozygous and heterozygous mutations in TNFRSF13B, encoding TACI, in 13 individuals with common variable immunodeficiency ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143554.RASHyu3Vs_e1Ae9pXdzHuOpgBvCWojKaGn1tzI4snLBpU130_provenance.
- NP143556.RAcorccR6ul2-YMMGtGpJBMgfnJ5Qf5FjM--teAGn0C5Q130_assertion description "[Mutations in TACI significantly predispose to autoimmunity and lymphoid hyperplasia in common variable immunodeficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143556.RAcorccR6ul2-YMMGtGpJBMgfnJ5Qf5FjM--teAGn0C5Q130_provenance.
- NP143564.RAdTya4lpPWAYM4sm3jtsL-ek_9qyIVu8V49qs9qjtpEo130_assertion description "[Reduced IL-10 secretion in common variable immunodeficiency patients seems to involve the cAMP-dependent protein kinase A type I system.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143564.RAdTya4lpPWAYM4sm3jtsL-ek_9qyIVu8V49qs9qjtpEo130_provenance.
- NP143567.RATm9kiv_uXeYfLtuPYR49s3CMBIUVhfINoO-KQHTFiAU130_assertion description "[4 of 19 unrelated individuals with common variable immunodeficiency and 1 of 16 individuals with IgA deficiency had a missense mutation in one allele of TNFRSF13B ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143567.RATm9kiv_uXeYfLtuPYR49s3CMBIUVhfINoO-KQHTFiAU130_provenance.
- NP143572.RAdw7vIhyO2pR5D5jHTbDGviycqLD00YSr8U9U_MIklRU130_assertion description "[Mutations cxause lethal and nonlethal forms of multiple pterygium syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143572.RAdw7vIhyO2pR5D5jHTbDGviycqLD00YSr8U9U_MIklRU130_provenance.
- NP143575.RAdEDT7oqpGXPzpePJoFwTR5DyTKhKVBsc3ormDoMTJrg130_assertion description "[DNA-sequence variants associated with IRF6 are major contributors to cleft lip, with or without cleft palate/contribution of variants in single genes to cleft lip or palate is an important consideration in genetic counseling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143575.RAdEDT7oqpGXPzpePJoFwTR5DyTKhKVBsc3ormDoMTJrg130_provenance.
- NP143576.RASk1orAPmtycmEmW5m_V41_wwQlfM6s6u9sRQLLSjWAM130_assertion description "[RPL5 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143576.RASk1orAPmtycmEmW5m_V41_wwQlfM6s6u9sRQLLSjWAM130_provenance.
- NP143577.RATDvdMNcnyx4TRmMqausGttBFQDXjjFIMcttPu6qRu5s130_assertion description "[decreasingly expressed in unaffected, cleft of the lip, alveolus with or without cleft palate, and patient with cleft palate only and thus further strength has been given to its role in the onset of the disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143577.RATDvdMNcnyx4TRmMqausGttBFQDXjjFIMcttPu6qRu5s130_provenance.
- NP143578.RAWYGArQWAIsN4WCB7frjVacZVI-8vQ9s1CH9Q-zZ2RXw130_assertion description "[Mothers with c.2756AG or GG genotype displayed a 2.195-fold increased risk of having a child with non-syndromic cleft lip with or without cleft palate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143578.RAWYGArQWAIsN4WCB7frjVacZVI-8vQ9s1CH9Q-zZ2RXw130_provenance.
- NP143584.RAdYsZ8B8dr8iZwu4KBJX9DDO-eEfOVtkMdQfMYOFXQxY130_assertion description "[These data are the first to suggest a role for SUMO1 gene variation in human non-syndromic cleft lip with or without cleft palate development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143584.RAdYsZ8B8dr8iZwu4KBJX9DDO-eEfOVtkMdQfMYOFXQxY130_provenance.
- NP143591.RAW0_jXYghUUQ0fNRfYUCuWKjwWMsly-Z1Row4wDNryO0130_assertion description "[Altered crosstalk between RA, GABAergic, and TGF-beta signaling systems could be involved in human cleft palate fibroblast phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143591.RAW0_jXYghUUQ0fNRfYUCuWKjwWMsly-Z1Row4wDNryO0130_provenance.
- NP143600.RAcmDaPhFuef72DdHbQttbNpMk7q9Y9bm6VtJ5LSBrs5c130_assertion description "[the contribution of MSX1 in the etiology of non-syndromic cleft lip/palate in the Chilean population ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143600.RAcmDaPhFuef72DdHbQttbNpMk7q9Y9bm6VtJ5LSBrs5c130_provenance.
- NP143604.RAeWi9_x0mzvW-EemxpykMRCs8ttWQ7ceSluI5VaUUiRk130_assertion description "[inverse relation between the mother's having the MTHFR C677T variant and cleft lip and palate suggests perturbation of maternal folate metabolism is of etiological importance ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143604.RAeWi9_x0mzvW-EemxpykMRCs8ttWQ7ceSluI5VaUUiRk130_provenance.
- NP143608.RAczY8WEME8EEEnC5yItJZlQurvVQJ0SaapeN8E_dRq-0130_assertion description "[Mutations in TGFA gene have no association with nonsyndromic cleft lip and palate in the sample from Rio Grande do Sul/, based on this study, it is not possible to determine the role played by TGFA in the expression of cleft lip and palate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143608.RAczY8WEME8EEEnC5yItJZlQurvVQJ0SaapeN8E_dRq-0130_provenance.
- NP143615.RAfuaCj2OYcwOH5NVZM9lUlgDhwqZyql_JeFhJzfSVes8130_assertion description "[a gene that when mutated increases susceptibility to colon cancer also is associated with cleft lip and palate ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143615.RAfuaCj2OYcwOH5NVZM9lUlgDhwqZyql_JeFhJzfSVes8130_provenance.
- NP143616.RAZAPnxJGCvDWW3CRmvH5-VQvkDYGS4TCRB7eVPe7iJsU130_assertion description "[Mutations within the PVRL1 gene represent risk factors for non-syndromic cleft lip with or without cleft palate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143616.RAZAPnxJGCvDWW3CRmvH5-VQvkDYGS4TCRB7eVPe7iJsU130_provenance.
- NP143619.RAfUpSs40RqV9dMj88rYdoFvmt2FNxcDdltWGo12dfELg130_assertion description "[Single nucleotide polymorphisms of the GAD67 gene are associated with nonsyndromic cleft lip with or without cleft palate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143619.RAfUpSs40RqV9dMj88rYdoFvmt2FNxcDdltWGo12dfELg130_provenance.
- NP143622.RAXdxfhR8Z0d-oYEL_b2GtxL2SEPYEo2-UkSdv486NO_I130_assertion description "[Regional expression of barx1 was observed in epithelium before mixed dentition, while during mixed dentition gene appeared in hyaline cartilage/of barx1 appears in cleft lip palate affected structures mainly in mixed dentition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143622.RAXdxfhR8Z0d-oYEL_b2GtxL2SEPYEo2-UkSdv486NO_I130_provenance.
- NP143629.RAe-vluLLyIZGB_4PHyZQFiRMY_v18ox2vNOIryjska5A130_assertion description "[FGF and FGFR may have a role in cleft lip and cleft palate ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143629.RAe-vluLLyIZGB_4PHyZQFiRMY_v18ox2vNOIryjska5A130_provenance.
- NP143631.RAdnDHocxW_nyFguLIxtTCHzIk5z1wTAskH7-efduwdFE130_assertion description "[FGF3, FGF7, FGF10, FGF18, and FGFR1 may have roles in nonsyndromic cleft lip and palate ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143631.RAdnDHocxW_nyFguLIxtTCHzIk5z1wTAskH7-efduwdFE130_provenance.
- NP143633.RAU_-RSon4d4tiBlGeVucnj0_MNAwtmDZLd2BRCKHPkYE130_assertion description "[These studies suggest that, through serine phosphorylation, Raptor-mTOR and S6K1 promote the depletion of IRS1 from specific intracellular pools in pathological states of insulin and IGF-I resistance and in lesions associated with tuberous sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143633.RAU_-RSon4d4tiBlGeVucnj0_MNAwtmDZLd2BRCKHPkYE130_provenance.
- NP143634.RAdUfVwSXAXDV7O9XzVYT_u2OpZTf7T9Rtghc7m6uJuVo130_assertion description "[Refractory epilepsy phenotype in tuberous sclerosis can be associated with the expression of multidrug resistance MDR-1 transporter in epileptogenic cortical tubers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143634.RAdUfVwSXAXDV7O9XzVYT_u2OpZTf7T9Rtghc7m6uJuVo130_provenance.
- NP143636.RAT2iATIRGdi_L96umtrfp4_Xg8OFInXCE-c_niXOX6Yk130_assertion description "[Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143636.RAT2iATIRGdi_L96umtrfp4_Xg8OFInXCE-c_niXOX6Yk130_provenance.
- NP143638.RAXgdcmw7WClIMojNYt7dDozD2lXEAhVl2V7zx8fpX3pE130_assertion description "[Specific alterations in TNF-alpha expression coupled with detection of numerous CD68-immunoreactive macrophages suggests activation of proinflammatory cytokine signaling pathways in the tuberous sclerosis complex brain that may culminate in cell death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143638.RAXgdcmw7WClIMojNYt7dDozD2lXEAhVl2V7zx8fpX3pE130_provenance.
- NP143640.RAXGDYQIBoAVxeBeWcfCwfYYbmDBjScfK80MXkyefspkw130_assertion description "[tsc1 gene expression is reduced in the majority of subependymal giant cell astrocytomas in tuberous sclerosis complex ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143640.RAXGDYQIBoAVxeBeWcfCwfYYbmDBjScfK80MXkyefspkw130_provenance.
- NP143641.RAVtp4ysZjFDIV9FG9Cp1tjTIjbtRdrxf_4m0rOsYoRdc130_assertion description "[loss of hamartin results in abnormal neurite elongation through Rho inactivation in NGF-treated PC12h cells, which may be associated with the neurological manifestations of Tuberous sclerosis complex.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143641.RAVtp4ysZjFDIV9FG9Cp1tjTIjbtRdrxf_4m0rOsYoRdc130_provenance.
- NP143647.RAf6X6XHv1iywx6fScfJ-NDLZ4gYtCtTALy4SHk9Xv31g130_assertion description "[Cortical tuber giant cells in a case of epileptogenic tuberous sclerosis showed predominantly nuclear hamartin, cytosolic tuberin, and hyperphosphorylation of S6.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143647.RAf6X6XHv1iywx6fScfJ-NDLZ4gYtCtTALy4SHk9Xv31g130_provenance.