Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP143658.RAfYyJMBdSmO82lx1Zl-oJ5DDG_r1NkEkBYOCJJ0uC4oA130_assertion description "[TSC1 and TSC2 mutations in tuberous sclerosis - used DHPLC analysis to facilitate the detection of a mosaic mutation, in the presence of a coexisting constitutional polymorphism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143658.RAfYyJMBdSmO82lx1Zl-oJ5DDG_r1NkEkBYOCJJ0uC4oA130_provenance.
- NP143665.RASDFcbDDOAGGKL3xsIjmw4Ntm_XqyO2-FIIFfo7BVCQo130_assertion description "[During conditions of cell stress, GADD34 forms a stable complex with tuberous sclerosis complex (TSC) 1/2, causes TSC2 dephosphorylation, and inhibits signaling by mammalian target of the rapamycin (mTOR).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143665.RASDFcbDDOAGGKL3xsIjmw4Ntm_XqyO2-FIIFfo7BVCQo130_provenance.
- NP143667.RASnvBPsI0wzoRTzx9gMjYz37j07fIPZ52FrjpKOsmG3A130_assertion description "[During conditions of cell stress, GADD34 forms a stable complex with tuberous sclerosis complex (TSC) 1/2, causes TSC2 dephosphorylation, and inhibits signaling by mammalian target of the rapamycin (mTOR).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143667.RASnvBPsI0wzoRTzx9gMjYz37j07fIPZ52FrjpKOsmG3A130_provenance.
- NP143677.RAXEFlTh1flk9rtcU51jjUlUdqSHTCUMyw7WPaIF9hVmc130_assertion description "[Upergulation of CAF-1 p48 subunit by overexpression of tuberous sclerosis gene products.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143677.RAXEFlTh1flk9rtcU51jjUlUdqSHTCUMyw7WPaIF9hVmc130_provenance.
- NP143678.RAaQvqi-KnE_m9eXyHD47rovSEczPRm_48RUa8bbfD4AE130_assertion description "[Specific alterations in NF-kappaB1 expression coupled with detection of numerous CD68-immunoreactive macrophages suggests activation of proinflammatory cytokine signaling pathways in the tuberous sclerosis complex brain that may culminate in cell death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143678.RAaQvqi-KnE_m9eXyHD47rovSEczPRm_48RUa8bbfD4AE130_provenance.
- NP143679.RAXYSCs2rQXcUMQmhM0RJlcmHcyEvT35h5odt9B1-guEA130_assertion description "[MCP-1 overexpressed in tuberous sclerosis lesions acts as a paracrine factor for tumor development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143679.RAXYSCs2rQXcUMQmhM0RJlcmHcyEvT35h5odt9B1-guEA130_provenance.
- NP143687.RAXFneI0xAnVL_9NPEayYTAM6KNPfyiAhgHF15QwoVsAc130_assertion description "[Prostate tumor cells selected by hypoxia, normoxia or hyperoxia utilize HIF-1alpha in different ways to allow cell survival/growth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143687.RAXFneI0xAnVL_9NPEayYTAM6KNPfyiAhgHF15QwoVsAc130_provenance.
- NP143693.RAZ-j20Udkf9XPVbuiyCzAAJCTTY7lhZTCkjWzFV65unY130_assertion description "[Promoter methylation of cyclin-Dependent Kinase Inhibitor p16 is associated with malignant fibrous histiocytomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143693.RAZ-j20Udkf9XPVbuiyCzAAJCTTY7lhZTCkjWzFV65unY130_provenance.
- NP143696.RAX3OfLCPNsrXOV98HFn8C36R5rKXJ0-h2spEZnJse5Xk130_assertion description "[HB-EGF might be a more important tumor growth regulator of malignant fibrous histiocytoma through autocrine or paracrine pathways, when compared with betacellulin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143696.RAX3OfLCPNsrXOV98HFn8C36R5rKXJ0-h2spEZnJse5Xk130_provenance.
- NP143698.RAXLOOuQVjUH8X_s09CZRh478wLhY-nBHFwdts8kLr4jk130_assertion description "[Ezrin expression in hepatic malignant fibrous histiocytoma can provide additional prognostic information and may be a potential target for new adjuvant therapies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143698.RAXLOOuQVjUH8X_s09CZRh478wLhY-nBHFwdts8kLr4jk130_provenance.
- NP143699.RAVNvcHGSOIEMAq1BucOH4_cUbWfgYibaDzLWWOo8o5xU130_assertion description "[Promoter methylation of retinoblastoma Protein is associated with malignant fibrous histiocytomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143699.RAVNvcHGSOIEMAq1BucOH4_cUbWfgYibaDzLWWOo8o5xU130_provenance.
- NP143705.RAcSU20bWwvCsP_QuN1YCqc5K6o4eRBbVvkjyTkHPSukk130_assertion description "[Angiotensinogen/renin transgenic rats develop hypertension/in the heart conduction sytsem leads to ventricular tachycardia and sudden arrhythmic death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143705.RAcSU20bWwvCsP_QuN1YCqc5K6o4eRBbVvkjyTkHPSukk130_provenance.
- NP143710.RATyw8hI7kkNbecvI9y3TqoWk672cQuzuJZZ75eAwraJY130_assertion description "[missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143710.RATyw8hI7kkNbecvI9y3TqoWk672cQuzuJZZ75eAwraJY130_provenance.
- NP143717.RAWJDyPyABHIMjp62ODrmK3z-qywdAZHyCL1u5W0GtFiI130_assertion description "[Suppressive effect of the Gly389 allele of the beta1-adrenergic receptor gene on the occurrence of ventricular tachycardia in dilated cardiomyopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143717.RAWJDyPyABHIMjp62ODrmK3z-qywdAZHyCL1u5W0GtFiI130_provenance.
- NP143728.RAdj4412S3Q1H3K7jQyfbPBDcCkXaF46gpArD4vFgrX0U130_assertion description "[A heterozygous G-to-A mutation at position 3823 (D1275N) in a highly conserved residue of exon 21 is associated with an autosomal dominant cardiac conduction disorder, sinus node dysfunction, arrhythmia, ventricular dilatation & dysfunction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143728.RAdj4412S3Q1H3K7jQyfbPBDcCkXaF46gpArD4vFgrX0U130_provenance.
- NP143733.RAadEV0EVKM5tX3CQfVsj01Dp-XaJmUfIh6s0t0WqPqtE130_assertion description "[Adrenomedullin protects against myocardial infarction, arrhythmia, and apoptosis in ischemia and reperfusion injury via suppression of oxidative stress-induced Bax and p38 MAPK phosphorylation and activation of the Akt-Bad-Bcl-2 signaling pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143733.RAadEV0EVKM5tX3CQfVsj01Dp-XaJmUfIh6s0t0WqPqtE130_provenance.
- NP143734.RAX4LqvYIJuazETu_CxL2eZOmGni-AjZIymFAEWzRnS7U130_assertion description "[Two missense mutations, S48P substitution and I246M affecting highly conserved amino acids were linked to hereditary Hypertrophic cardiomyopathy characterized by early onset of symptoms, pronounced cardiac hypertrophy, and cardiac arrhythmias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143734.RAX4LqvYIJuazETu_CxL2eZOmGni-AjZIymFAEWzRnS7U130_provenance.
- NP143737.RAW7giwjA1031Fj_Fb5M1OQdkGl7gaPbwAiOsaysgsZ1Q130_assertion description "[G-CSF treatment induced reduced expression of CXCR4, VLA-4 and VEGFR-1 in patients with liver failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143737.RAW7giwjA1031Fj_Fb5M1OQdkGl7gaPbwAiOsaysgsZ1Q130_provenance.
- NP143742.RAVKM5oFB2w9YWaEasuLOvV4_-h6QLVE4CjOL3-qm_eh4130_assertion description "[The increased expression of gp210 in small bile ducts is possibly involved in autoimmune response to gp210 leading to the progression to end-stage hepatic failure in primary biliary cirrhosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143742.RAVKM5oFB2w9YWaEasuLOvV4_-h6QLVE4CjOL3-qm_eh4130_provenance.
- NP143743.RAXBTZ-Ewo0ykFa5DzhN0fVOcQ0OR5-QwcdigtubUp548130_assertion description "[G-CSF treatment induced reduced expression of CXCR4, VLA-4 and VEGFR-1 in patients with liver failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143743.RAXBTZ-Ewo0ykFa5DzhN0fVOcQ0OR5-QwcdigtubUp548130_provenance.
- NP143752.RASsS44IZYW-_ySplQq5ByIjP7MAKl9hTrOTiPk22D2v8130_assertion description "[NF2 has a role in inhibiting schwannoma cell proliferation through promoting PDGFR degradation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143752.RASsS44IZYW-_ySplQq5ByIjP7MAKl9hTrOTiPk22D2v8130_provenance.
- NP143757.RAXfOZNUbqGWWSQfNpATsGl8jPOhuUhIm_WzNLP2M3thw130_assertion description "[HRS inhibits Stat3 activation in schwannoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143757.RAXfOZNUbqGWWSQfNpATsGl8jPOhuUhIm_WzNLP2M3thw130_provenance.
- NP143758.RAZ9cB6rvbIe4SBrgaLqXpzJdDOg3-9J_Hl3puzSbpQRs130_assertion description "[Data show that Rac1 plays a significant role in the pathological adhesion of Schwannoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143758.RAZ9cB6rvbIe4SBrgaLqXpzJdDOg3-9J_Hl3puzSbpQRs130_provenance.
- NP143759.RARxwfQWY_Kq5SX9RT5nqSRjA_W0YbwqxpWQZBDfhYJ4Y130_assertion description "[an enhanced activation of Rac1 in primary human schwannoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143759.RARxwfQWY_Kq5SX9RT5nqSRjA_W0YbwqxpWQZBDfhYJ4Y130_provenance.
- NP143761.RAedS_T0N_du8Zu_IX9MJn_nGMskcreCu5auwg7WFwcaU130_assertion description "[Data found homozygous deletions in exon 3 of the p16INK4a gene in two schwannomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143761.RAedS_T0N_du8Zu_IX9MJn_nGMskcreCu5auwg7WFwcaU130_provenance.
- NP143764.RASeuOUbEGd0kyl4VvI4gNkTk7Rufgx2yuKBIcGNpGhCw130_assertion description "[Perinuclear collapse of the intermediate filament GFAP is demonstrated in primary schwannoma cells, which become motile, unspecifically ensheathing the extracellular matrix and forming pseudomesaxons.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143764.RASeuOUbEGd0kyl4VvI4gNkTk7Rufgx2yuKBIcGNpGhCw130_provenance.
- NP143770.RASEj6NOHdJJyqc_EiQ9BFrHqWrGbJo2yTwe57KQmapOY130_assertion description "[The expression signals of BMP-4 mRNA in malignant schwannoma were relatively lower than in benign lesions ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143770.RASEj6NOHdJJyqc_EiQ9BFrHqWrGbJo2yTwe57KQmapOY130_provenance.
- NP143772.RAXCDwGMj5m6Yw8VlRQZ-6aFZ0tTBCaoHt0KKoD311dHw130_assertion description "[Results describe the expression of angiopoietin-1, 2 and 4 and Tie-1 and 2 in gastrointestinal stromal tumors, leiomyomas and schwannomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143772.RAXCDwGMj5m6Yw8VlRQZ-6aFZ0tTBCaoHt0KKoD311dHw130_provenance.
- NP143775.RAfNCxtVh5GwQRtR6YYHHB6fX9YSnZ_GszGXYQWxyEu9g130_assertion description "[Ets-1 plays an important role in the growth and differentiation of gastrointestinal stromal tumors, leiomyomas and schwannomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143775.RAfNCxtVh5GwQRtR6YYHHB6fX9YSnZ_GszGXYQWxyEu9g130_provenance.
- NP143778.RAQ3g7b4amC-LfJx4jAfYO8KsOFGt8fZvs6RxmRxlgmlA130_assertion description "[gene mutated in variant late-infantile neuronal ceroid lipofuscinosis (CLN6) and in nclf mutant mice encodes a novel predicted transmembrane protein ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143778.RAQ3g7b4amC-LfJx4jAfYO8KsOFGt8fZvs6RxmRxlgmlA130_provenance.
- NP143782.RAb4HWY3cZXfwns_ljwzzq-2n8waCoyA5fB0xBJMW3Sx8130_assertion description "[A novel missense mutation in CLN5 was found in a Colombian family with juvenile-onset neuronal ceroid lipofuscinosis: c/> A causing Arg112His.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143782.RAb4HWY3cZXfwns_ljwzzq-2n8waCoyA5fB0xBJMW3Sx8130_provenance.
- NP143783.RASsOs7gS6pvGAdhAagH8PrlPnAdB3LPLTKePFTXyftqs130_assertion description "[juvenile and variant late infantile neuronal ceroid lipofuscinoses have mutated CLN genes encoding lysosomal proteins (review) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143783.RASsOs7gS6pvGAdhAagH8PrlPnAdB3LPLTKePFTXyftqs130_provenance.
- NP143785.RAYxn1DofegxC9C7TEYE5oK-0diydH8g_Zhr6Vv6QIL-w130_assertion description "[Batten disease, an inherited neurodegenerative storage disease affecting children, results from the autosomal recessive inheritance of mutations in Cln3/is resident in the lysosomal/endosomal membrane.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143785.RAYxn1DofegxC9C7TEYE5oK-0diydH8g_Zhr6Vv6QIL-w130_provenance.
- NP143787.RAf2rStd6A0Zy2_j6kon4xrN7KlxpCkRu7CaX1g8dnIKc130_assertion description "[juvenile and variant late infantile neuronal ceroid lipofuscinoses have mutated CLN genes encoding lysosomal proteins (review) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143787.RAf2rStd6A0Zy2_j6kon4xrN7KlxpCkRu7CaX1g8dnIKc130_provenance.
- NP143791.RAbklw1gCVJXhOh2pGCDRJ6HCYvh2Yv36kxJ8tYTbqCzk130_assertion description "[We describe using intermittent prednisolone and finding autoantibodies to GAD65 in juvenile neuronal ceroid lipofuscinosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143791.RAbklw1gCVJXhOh2pGCDRJ6HCYvh2Yv36kxJ8tYTbqCzk130_provenance.
- NP143797.RAQs4XIjo_OccrRl8obsmpCBWf7lssHOoAxl7gvq0FX2A130_assertion description "[CLN2 gene mutations may result in low cerebrospinal fluid pterin production in classical neuronal ceroid lipofuscinoses of late infantile onset.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143797.RAQs4XIjo_OccrRl8obsmpCBWf7lssHOoAxl7gvq0FX2A130_provenance.
- NP143814.RARmnrerEX-kj-J4CBCjsokXyxNPCNqRZ-n250vGcPBDg130_assertion description "[We demonstrate, for the first time in human skeletal muscle, that the regulation of Akt and its downstream signalling pathways GSK-3beta, mTOR and Foxo1 are associated with both the skeletal muscle hypertrophy and atrophy processes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143814.RARmnrerEX-kj-J4CBCjsokXyxNPCNqRZ-n250vGcPBDg130_provenance.
- NP143820.RAYu8wZ9-J6Vtnnw82q6id4LR6IncupKX2Y85v1UbEUfs130_assertion description "[TSP-1 might mediate AGE-induced distal renal tubule hypertrophy/are several putative transcription factor binding sites in the TSP-1 promoter, including those for AP-1, CREB, NF-kappaB, SRF, and HSF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143820.RAYu8wZ9-J6Vtnnw82q6id4LR6IncupKX2Y85v1UbEUfs130_provenance.
- NP143826.RASdFJzUAVufbZpLCy82HGOd6cJc-4EwyeKoRLxR5GDSI130_assertion description "[ACE gene polymorphisms were associated with age-related left ventricle remodeling and hypertrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143826.RASdFJzUAVufbZpLCy82HGOd6cJc-4EwyeKoRLxR5GDSI130_provenance.
- NP143829.RARdv2tSj3ry4l1lbNm99xKMG0zl-Xhrvetqt4N-qzECc130_assertion description "[the effects of Ang II and MR activation in the heart are additive affecting ventricular hypertrophy and function ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143829.RARdv2tSj3ry4l1lbNm99xKMG0zl-Xhrvetqt4N-qzECc130_provenance.
- NP143833.RAYW649ZS3_568QyJgryiMQ2ZRJQ2UrGlOGHRYCkg7JNM130_assertion description "[E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular adhesion molecule-1 (VCAM-1) were measured in serum from hypertensive patients with LV hypertrophy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143833.RAYW649ZS3_568QyJgryiMQ2ZRJQ2UrGlOGHRYCkg7JNM130_provenance.
- NP143835.RARMtzemV3wPtiT5o3CKJTfFtZPR_q8Fpl2fzO4_diM1I130_assertion description "[Loss-of-function mutation in myostatin gene caused muscle hypertrophy; provides strong evidence myostatin plays important role in regulation of muscle mass in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143835.RARMtzemV3wPtiT5o3CKJTfFtZPR_q8Fpl2fzO4_diM1I130_provenance.
- NP143840.RAbjNlsSPm2Ot2M7aXPIshBSReLYvdlo4ZkSmZU1UoqQg130_assertion description "[We demonstrate, for the first time in human skeletal muscle, that the regulation of Akt and its downstream signalling pathways GSK-3beta, mTOR and Foxo1 are associated with both the skeletal muscle hypertrophy and atrophy processes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143840.RAbjNlsSPm2Ot2M7aXPIshBSReLYvdlo4ZkSmZU1UoqQg130_provenance.
- NP143842.RAcfOLoJL9mkv6IuW3DEZU8zBuGGoq3siHlWGt522xSYg130_assertion description "[Mutations in POLG, necessary for mtDNA biogenesis, increased risk for defective mtDNA replication, leading to LV hypertrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143842.RAcfOLoJL9mkv6IuW3DEZU8zBuGGoq3siHlWGt522xSYg130_provenance.
- NP143849.RAXDHh0TumLgfncJzpkY-qLOSwwAiJYeL_UIbftTKqBcA130_assertion description "[H11 kinase is a novel mediator of myocardial hypertrophy in vivo ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143849.RAXDHh0TumLgfncJzpkY-qLOSwwAiJYeL_UIbftTKqBcA130_provenance.
- NP143851.RATVMf3oEpOtC_tKsCsRDC5OZiaBQ9v3DQwZAsn_IRDiY130_assertion description "[Small increments in p300 are necessary and sufficient to drive myocardial hypertrophy, possibly through acetylation of MEF2 and upstream of signals promoting phosphorylation or nuclear export of histone deacetylases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143851.RATVMf3oEpOtC_tKsCsRDC5OZiaBQ9v3DQwZAsn_IRDiY130_provenance.
- NP143852.RAdzy9tamTCXzADY9v0Zjm3-frg3MaLCwEAZKipceSl98130_assertion description "[TRPC channel overexpression may be partially responsible for the increased pulmonary artert smooth muscle cell proliferation and pulmonary vascular medial hypertrophy in pulmonary hypertension patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143852.RAdzy9tamTCXzADY9v0Zjm3-frg3MaLCwEAZKipceSl98130_provenance.
- NP143853.RAchdNkSFOCV__xTrZSmUKPRH3vcOZpZASNyPv8LRu570130_assertion description "[This study found an up-regulation of TIMP-1, TIMP-2 and MMP-2 RNA in Duchenne Muscular Dystrophy muscle.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143853.RAchdNkSFOCV__xTrZSmUKPRH3vcOZpZASNyPv8LRu570130_provenance.
- NP143855.RAdv2af8REfUPdiGq394RVgwXZm6kyXCAzHSjVgad-VAA130_assertion description "[Augmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143855.RAdv2af8REfUPdiGq394RVgwXZm6kyXCAzHSjVgad-VAA130_provenance.
- NP143856.RAfNhxJJrUeY8qiznZPYKwEmBPR-M1t3-kXqxJ5koySEA130_assertion description "[Augmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143856.RAfNhxJJrUeY8qiznZPYKwEmBPR-M1t3-kXqxJ5koySEA130_provenance.
- NP143859.RAc6WlOucuGbbLv5TFcpq7aIMMEbyqm21npktp6dXXwJg130_assertion description "[The frequency of deletions was 67.5% in 26 Mexican families with signs of Duchenne/Becker muscular dystrophy/were at the 5'end & in the central region, exons 44 to 52, of the gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143859.RAc6WlOucuGbbLv5TFcpq7aIMMEbyqm21npktp6dXXwJg130_provenance.
- NP143870.RAZNlVa_M5Y_79HM1oa-FJweNF96EUBeiTxZ4zKp7dlWA130_assertion description "[Both DMD and Becker muscular dystrophy can result from out-of-frame pseudoexons, with the difference in phenotype being due to variable efficiency of the newly generated splicing signal.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143870.RAZNlVa_M5Y_79HM1oa-FJweNF96EUBeiTxZ4zKp7dlWA130_provenance.
- NP143875.RAfZSY-TqPpNhmZnaQhMmvaau3k-XnIrRYFTqjsXW4eBA130_assertion description "[RAMP may play a role in the regeneration of skeletal muscle, and its down-regulation could be involved in the progression of Duchenne muscular dystrophy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143875.RAfZSY-TqPpNhmZnaQhMmvaau3k-XnIrRYFTqjsXW4eBA130_provenance.
- NP143882.RAd8a1gXH8NGTQVX-PjMOUj72gzOs5r9659uvTAJmzu3A130_assertion description "[results suggest that HLA genotype relates to the muscular necrosis and the pathogenesis of Duchenne muscular dystrophy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143882.RAd8a1gXH8NGTQVX-PjMOUj72gzOs5r9659uvTAJmzu3A130_provenance.
- NP143884.RARpoDz5J_zT5QMYINx6gtVhb6QWB-zzrKQ25sBBkka2Q130_assertion description "[This study found an up-regulation of TIMP-1, TIMP-2 and MMP-2 RNA in Duchenne Muscular Dystrophy muscle.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143884.RARpoDz5J_zT5QMYINx6gtVhb6QWB-zzrKQ25sBBkka2Q130_provenance.
- NP143886.RAX4OAx0sTRFlnoGW2PfMNGgnmRAU-mlULeDvUuh6HrzA130_assertion description "[data suggest that the N363S GRL polymorphism may be implicated in the long term response to glucocorticoids in patients with Duchenne muscular dystrophy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143886.RAX4OAx0sTRFlnoGW2PfMNGgnmRAU-mlULeDvUuh6HrzA130_provenance.
- NP143889.RAYGx6yva2GKlu7YeJhkkRZEBFNsYqZtOcBSo7JaV5Epw130_assertion description "[Inhaled IL-5 modulated eosinophil progenitor numbers in both the airways and bone marrow of asthmatics and induced local eosinophilia in non-asthmatics.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143889.RAYGx6yva2GKlu7YeJhkkRZEBFNsYqZtOcBSo7JaV5Epw130_provenance.
- NP143890.RAZzrPioeEDH9yCiU8lF5Tprps33_ns_B--X88niAKkYw130_assertion description "[IL-5 overexpression is associated with eosinophilia in T-cell lymphomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143890.RAZzrPioeEDH9yCiU8lF5Tprps33_ns_B--X88niAKkYw130_provenance.
- NP143891.RAeqz91mLmJaUE9U111yAhuFP1jsfXJUwdZ1993fmy-EM130_assertion description "[FIP1L1-PDGFRA is a relatively infrequent but treatment-relevant mutation in primary eosinophilia that is indicative of an underlying systemic mastocytosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143891.RAeqz91mLmJaUE9U111yAhuFP1jsfXJUwdZ1993fmy-EM130_provenance.
- NP143893.RAVYkMPPujogMDMyHKjgbyZJgZVStXOE7GRDgfXjBiQas130_assertion description "[FIP1L1-PDGFRA is a relatively infrequent but treatment-relevant mutation in primary eosinophilia that is indicative of an underlying systemic mastocytosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143893.RAVYkMPPujogMDMyHKjgbyZJgZVStXOE7GRDgfXjBiQas130_provenance.
- NP143895.RAcGL42F92T8xO89ypYiLvIUNGPPwM7sZg3nDSQ8Gdwkk130_assertion description "[used fluorescence in situ hybridization to detect deletion of the CHIC2 locus at 4q12 as a surrogate for the FIP1L1-PDGFRA fusion and was observed in bone marrow cells for 3 of 5 patients with systemic mast cell disease associated with eosinophilia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143895.RAcGL42F92T8xO89ypYiLvIUNGPPwM7sZg3nDSQ8Gdwkk130_provenance.
- NP143896.RAViBfn-Re1LFHdCbVxeCmATtt4TxZUTJ_RgOrJs-NTVg130_assertion description "[Chronic myelocytic leukemia with eosinophilia, t (9; 12) (q34; p13), and ETV6-ABL gene rearrangement: case report and review of the literature.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143896.RAViBfn-Re1LFHdCbVxeCmATtt4TxZUTJ_RgOrJs-NTVg130_provenance.
- NP143900.RAdbK1l8ADSu8ayLARYoZUHVOnFcuf77DQJ69nJ_jM_n8130_assertion description "[TARC overexpression is associated with eosinophilia in T-cell lymphomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143900.RAdbK1l8ADSu8ayLARYoZUHVOnFcuf77DQJ69nJ_jM_n8130_provenance.
- NP143903.RAeHug5zyuKUFc4v6987D6ssFnuMYnoGolzEgSu9zt4Sk130_assertion description "[Clonal CD8+/Vbeta+ T cell expansions might be useful as a disease marker in Churg Strauss Syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143903.RAeHug5zyuKUFc4v6987D6ssFnuMYnoGolzEgSu9zt4Sk130_provenance.
- NP143907.RAQ4_4nOW2uk1XQvMbBSYaEf5oF1ZLENVW9gAQi_JCLaY130_assertion description "[These alterations in TRAIL receptor 3 expression might be involved in the molecular pathogenesis of Churg-Strauss syndrome eosinophilia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143907.RAQ4_4nOW2uk1XQvMbBSYaEf5oF1ZLENVW9gAQi_JCLaY130_provenance.
- NP143911.RAVa0J-WjO_E8bKy1rnPZe0GTyS1r2o8m2iaavreV8KG8130_assertion description "[The CD11c antibody was both sensitive and specific for hairy cell leukemia, even in cases with minimal infiltration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143911.RAVa0J-WjO_E8bKy1rnPZe0GTyS1r2o8m2iaavreV8KG8130_provenance.
- NP143925.RASkhZt5vcM_TO5AhvW3n58Q3ztDC1KOEs3cmnPbqBXMY130_assertion description "[testing demonstrates NY-BR-1 in a mostly focal fashion in the epithelia of ducts and acini of the mammary gland/tumors, homogenous staining can be seen in almost all ductal carcinomas in situ and/or the intraductal component of invasive carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143925.RASkhZt5vcM_TO5AhvW3n58Q3ztDC1KOEs3cmnPbqBXMY130_provenance.
- NP143927.RAc17jRnzWJxC_SN1zAL6BihrZ9CGRM5hPuxPPG_02oc0130_assertion description "[Grade 1 invasive ductal carcinoma have a higher incidence of lymph node metastasis and may have Her-2-neu overexpression compared to tubular carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143927.RAc17jRnzWJxC_SN1zAL6BihrZ9CGRM5hPuxPPG_02oc0130_provenance.
- NP143930.RARbqLvYTBF_YRldy2JsUvkbLj47BSnPaNu9J4tBwGqoU130_assertion description "[VEGF and Ang-2 may have roles in microvessel growth in invasive ductal carcinoma of the breast ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143930.RARbqLvYTBF_YRldy2JsUvkbLj47BSnPaNu9J4tBwGqoU130_provenance.
- NP143939.RAfEQGVNAyZ1P_RE6QkIe95Fa3Q9XAGwl-YArsl-3-FIU130_assertion description "[The association between XRCC1-Arg399Gln polymorphism and ductal carcinoma was statistically significant (P = 0.02).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143939.RAfEQGVNAyZ1P_RE6QkIe95Fa3Q9XAGwl-YArsl-3-FIU130_provenance.
- NP143943.RASRqW12UqEpg2OtZXu9KD9r9XnHiJgaN8IE7ae7x5rHY130_assertion description "[P63 is a specific myoepithelial cell marker in normal breast tissue and is expressed in a minority of breast carcinomas, being seen only in grade III ductal carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143943.RASRqW12UqEpg2OtZXu9KD9r9XnHiJgaN8IE7ae7x5rHY130_provenance.
- NP143947.RAflh7f7Tsf_FZ1eGcvJVCSYo501izMI_6EMxzZaGeBg0130_assertion description "[Biallelic inactivation of SMAD4 through homozygous deletion in breast cancer cell lines and invasive ductal carcinomas.(]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143947.RAflh7f7Tsf_FZ1eGcvJVCSYo501izMI_6EMxzZaGeBg0130_provenance.
- NP143948.RASmVgegT__sAt4NoWbsP1CoG_3VIE1E2y-dIk6oRgWwY130_assertion description "[VEGF and Ang-2 may have roles in microvessel growth in invasive ductal carcinoma of the breast ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143948.RASmVgegT__sAt4NoWbsP1CoG_3VIE1E2y-dIk6oRgWwY130_provenance.
- NP143953.RAYWd4a3o41ZT-Q79BCVW9eOCQlt6WzNmeMr1Fj2WrkHw130_assertion description "[VEGF expression plays a role in promoting angiogenesis in invasive ductal carcinoma of the breast, and p53 is likely to be involved in regulating VEGF expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143953.RAYWd4a3o41ZT-Q79BCVW9eOCQlt6WzNmeMr1Fj2WrkHw130_provenance.
- NP143954.RAfFhhLZFOiybBNS_Eo-u02-jnsBvkDi0xyY-cJYQgOXg130_assertion description "[The farnesoid X receptor (FXR) was detected in normal and tumor breast tissue, with a high level of expression in ductal epithelial cells of normal breast and infiltrating ductal carcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143954.RAfFhhLZFOiybBNS_Eo-u02-jnsBvkDi0xyY-cJYQgOXg130_provenance.
- NP143956.RAT_gLmR1fCVCY-77-qGRrXHhLyN4X50Uj_y803obfJyQ130_assertion description "[reduced PTEN expression may be an independent prognostic indicator in patients with invasive ductal carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143956.RAT_gLmR1fCVCY-77-qGRrXHhLyN4X50Uj_y803obfJyQ130_provenance.
- NP143965.RAblnTYgNHKsHerEhiCNPWWqx_KuDOXX_HUmC4HJcM4k8130_assertion description "[HER2 appears to lack a critical role in the progression from ductal carcinoma in situ and invasive ductal carcinoma and HER2 status is maintained in metastatic lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143965.RAblnTYgNHKsHerEhiCNPWWqx_KuDOXX_HUmC4HJcM4k8130_provenance.
- NP143972.RAaMeM_Le6cUkEWUo_LOrmEP8L5wLlO-BDdGrJslz4SJM130_assertion description "[It is suggested that S100A8 is S100A9-dependently expressed and acquires the protein stability by S100A8/A9 heterocomplex formation; S100A8 and S100A9 overexpression should be considered marker of poor prognosis in invasive ductal carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143972.RAaMeM_Le6cUkEWUo_LOrmEP8L5wLlO-BDdGrJslz4SJM130_provenance.
- NP143975.RAejuyKLT5HgOIQqTKxCn-tgLy6S0SdYAoSDNR-9-Cxz4130_assertion description "[HbE carrier status has been shown to confer protection against Plasmodium falciparum malaria ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143975.RAejuyKLT5HgOIQqTKxCn-tgLy6S0SdYAoSDNR-9-Cxz4130_provenance.
- NP143981.RAb8w0It8ODLp-UdOVube5g_MpeSbfHVxy8-4XebiN0Qc130_assertion description "[levels of IL-12 represent a reliable parameter to predict the progression of Plasmodium falciparum malaria, which may be complemented or modulated by IL-18 and TGF-beta ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143981.RAb8w0It8ODLp-UdOVube5g_MpeSbfHVxy8-4XebiN0Qc130_provenance.
- NP143984.RAYpLfAyjuVWJr0C1HToOTUUMxhtGRpWAQTwSjOsXoVNA130_assertion description "[IFN-gamma plays a role in regulating T helper 1-type immune responses in neonates born to mothers with placental falciparum malaria at delivery.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143984.RAYpLfAyjuVWJr0C1HToOTUUMxhtGRpWAQTwSjOsXoVNA130_provenance.
- NP143989.RAb684JoSik9zzCz0MH5lGSKcZIDqwgtcoKXiA2pHp310130_assertion description "[NKG2D ligand induction may participate in the amplification loop that leads to tissue damage during acute graft-versus-host disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143989.RAb684JoSik9zzCz0MH5lGSKcZIDqwgtcoKXiA2pHp310130_provenance.
- NP143991.RAc9oUd1H8orEz-Dhs5vZzDMda1gDSU03OnOqpJkJHsNI130_assertion description "[is a critical mediator for the development of autologous graft-versus-host disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143991.RAc9oUd1H8orEz-Dhs5vZzDMda1gDSU03OnOqpJkJHsNI130_provenance.
- NP143992.RAYniCmy_jjWxVetBPt1J6UiETG-27r4KZN2sK1Gzx5MQ130_assertion description "[this preliminary study on 56 donor-recipient pairs revealed IL-6-174 single nucleotide polymorphisms as a risk factor for the development of acute graft-versus-host disease and decreased survival after aHSCT ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143992.RAYniCmy_jjWxVetBPt1J6UiETG-27r4KZN2sK1Gzx5MQ130_provenance.
- NP143997.RAfBqsTRTW_X4ixYvERlA0eGAM_7nG_PYoqYgDen3Wlk4130_assertion description "[polymorphism is associated with the incidence of graft-versus-host disease and relapse rate in unrelated bone marrow transplantation (uBMT) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP143997.RAfBqsTRTW_X4ixYvERlA0eGAM_7nG_PYoqYgDen3Wlk4130_provenance.
- NP144001.RAYMSUYM6wVR4cjpQtH_xn6o5AaSWPmQwaYKm_zizoLTc130_assertion description "[Review: role in acute graft-vs-host disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144001.RAYMSUYM6wVR4cjpQtH_xn6o5AaSWPmQwaYKm_zizoLTc130_provenance.
- NP144003.RAaiFrQ4B329Wy84S7ymT0FkINp4oh6E3aXR0ioSx2ct8130_assertion description "[Polymorphism of the HSP70-hom gene is associated with the development of posttransplant complications/HSP-AA homozygous genotype is a risk factor for acute graft-versus-host disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144003.RAaiFrQ4B329Wy84S7ymT0FkINp4oh6E3aXR0ioSx2ct8130_provenance.
- NP144013.RAWGhasv1CGhm1vhwxu7xGM1rpdEAhUNqwIcthrhHLiLI130_assertion description "[HLA-G production by mesenchymal cells may provide a rationale for their immunomodulatory properties in preventing graft vs host disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144013.RAWGhasv1CGhm1vhwxu7xGM1rpdEAhUNqwIcthrhHLiLI130_provenance.
- NP144019.RAd5ml0jFS4W8Wp0a0mpCd3pfVlf_RCWwBBtbn80X1zPM130_assertion description "[The expression of TFF3 in chronic graft-versus-host disease of the liver is increased in response to bile duct damage and repair.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144019.RAd5ml0jFS4W8Wp0a0mpCd3pfVlf_RCWwBBtbn80X1zPM130_provenance.
- NP144021.RAQI42RNqY7fwHrOpBMR9a21GI06oC7-Q_Le2k1fd3Wow130_assertion description "[Association of graft vs host disease and stem cell transplantation mortality with NOD2/CARD15 single nucleotide polymorphism ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144021.RAQI42RNqY7fwHrOpBMR9a21GI06oC7-Q_Le2k1fd3Wow130_provenance.
- NP144022.RAeNSNss9FyMuPL_E6LOX5Dea4PSqpugi2-kflpPszQK8130_assertion description "[BAFF has a role in B-cell activation in patients with active chronic graft-versus-host disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144022.RAeNSNss9FyMuPL_E6LOX5Dea4PSqpugi2-kflpPszQK8130_provenance.
- NP144025.RAaB1gpbtWbn1JqT3rAffMR6JEog4DYDvrjTIVJQ0E9Vg130_assertion description "[Foxp3 regulatory gene expression may have a role in graft-versus-host disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144025.RAaB1gpbtWbn1JqT3rAffMR6JEog4DYDvrjTIVJQ0E9Vg130_provenance.
- NP144027.RAfPwvydCbJqtSmCNxc0OreosYbY9TjZFKPHWRtH1uu8I130_assertion description "[In focal nodular hyperplasia, Ang-1 was significantly up-regulated, Ang-2 was down-regulated, and the Ang-1/Ang-2 ratio was highly and specifically increased.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144027.RAfPwvydCbJqtSmCNxc0OreosYbY9TjZFKPHWRtH1uu8I130_provenance.
- NP144030.RAc5TJJjAegdL2jealt_DifCgDXKAulOuVPhQWeekhTKA130_assertion description "[beta-catenin, which participates in the Wnt signaling pathway, might play a more important role in the formation of hepatic adenoma than in that of focal nodular hyperplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144030.RAc5TJJjAegdL2jealt_DifCgDXKAulOuVPhQWeekhTKA130_provenance.
- NP144032.RAf6wpNkM7qbi02hmm0YatUY6r_8YCJGKzmdnlp6D5vYg130_assertion description "[Distinct cytokeratin 7, cytokeratin 19, & neuronal cell adhesion molecule staining patterns are seen in hepatic adenoma & focal nodular hyperplasia possibly suggest activation of different subsets of hepatic progenitor/stem cell.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144032.RAf6wpNkM7qbi02hmm0YatUY6r_8YCJGKzmdnlp6D5vYg130_provenance.
- NP144034.RAaCNbgHxqAoQcg8tgr7WT3vHFTkssYPRuizxGq4lV9CE130_assertion description "[GAG modification of NRP1 plays a critical role in modulating VEGF signaling, and may provide new insights into physiological and pathological angiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144034.RAaCNbgHxqAoQcg8tgr7WT3vHFTkssYPRuizxGq4lV9CE130_provenance.
- NP144037.RAeuvnc1V5cLfD0BFYTsS5Wy-KuKOa7fZcBXlAxajD2hY130_assertion description "[These results provide genetic evidence that alpha6beta4 signaling promotes the onset of the invasive phase of pathological angiogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144037.RAeuvnc1V5cLfD0BFYTsS5Wy-KuKOa7fZcBXlAxajD2hY130_provenance.
- NP144040.RAdX0LL4tWg5hDKTy_nCbLXJQWavvF3VH1mHTl_KfbgJs130_assertion description "[VEGF binds to CTGF and degrades MMPs, inducing physiological or pathologic angiogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144040.RAdX0LL4tWg5hDKTy_nCbLXJQWavvF3VH1mHTl_KfbgJs130_provenance.
- NP144044.RASqoiAruy0dwZqixUuDd8kxwlQp7vMI5HX0Kt7CP6Guo130_assertion description "[We discuss Wnts and a novel Frizzled ligand, Norrin, in physiological and pathological angiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144044.RASqoiAruy0dwZqixUuDd8kxwlQp7vMI5HX0Kt7CP6Guo130_provenance.
- NP144049.RAco2vzcO7lKYE3bUUdBbTr4jp_GWfxGmVTZktWM1kjGo130_assertion description "[Ocular surface inflammation, tear film instability, and decreased conjunctival MUC5AC mRNA expression were thought to be important in the pathogenesis of noninfectious corneal shield ulcers in atopic ocular surface disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144049.RAco2vzcO7lKYE3bUUdBbTr4jp_GWfxGmVTZktWM1kjGo130_provenance.