Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP144410.RAfPYIvyI4WoWaAYj4m2KpLl87Bv4HVhwHDk8xvNq1gWM130_assertion description "[Molecular analysis of spinal muscular atrophy and modification of the phenotype by SMN2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144410.RAfPYIvyI4WoWaAYj4m2KpLl87Bv4HVhwHDk8xvNq1gWM130_provenance.
- NP144416.RAZDBTsIGmPHa5aJAIgoptQuQGtv_H5-1g6W_Q3US_65w130_assertion description "[exon usage is regulated by the extended inhibitory context at the 5'end of exon 7 in SMN2 protein in spinal muscular atrophy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144416.RAZDBTsIGmPHa5aJAIgoptQuQGtv_H5-1g6W_Q3US_65w130_provenance.
- NP144418.RAWPXhXNkKF67TR3dAXesE2Yk7Nzdsigr_t-tz7HZoGHo130_assertion description "[In spinal muscular atrophy (SMA), SMN2 is not able to compensate for the loss of SMN1 due to exclusion of exon 7/we describe a novel inhibitory element located immediately downstream of the 5'splice site in intron 7.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144418.RAWPXhXNkKF67TR3dAXesE2Yk7Nzdsigr_t-tz7HZoGHo130_provenance.
- NP144420.RAXthTHPW-JIrbzJr-xIrU8kVJJlQ9M0CMKJoLp9LQNGs130_assertion description "[SMN transcript instability does not play a role in the disease mechanism, suggesting that therapeutic modulation of messenger RNA degradation would not target a molecular defect in patients with spinal muscular atrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144420.RAXthTHPW-JIrbzJr-xIrU8kVJJlQ9M0CMKJoLp9LQNGs130_provenance.
- NP144425.RAV4bceBRwIcALx5TdwC5GyQPyiXG7wEkKTr9iFzeJFew130_assertion description "[Data show that SMN1 copy number could be detected precisely by real-time fluorescence quantitative PCR and the screening of gene carriers of spinal muscular atrophy could provide essential data for genetic counseling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144425.RAV4bceBRwIcALx5TdwC5GyQPyiXG7wEkKTr9iFzeJFew130_provenance.
- NP144428.RAXDjJRNTkdI-ZrrNBdoJHX3jUczhRc525fUYb-YEygLE130_assertion description "[Homozygous absence of SMN1 exons 7 and 8, or exon 7 only, was found in 80% of childhood spinal muscular atrophy patients/those patients, 45% were also deleted for NAIP exon 5.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144428.RAXDjJRNTkdI-ZrrNBdoJHX3jUczhRc525fUYb-YEygLE130_provenance.
- NP144429.RAd9vBqnn59Yhh-32k7SLVGcGw3pD4ZcH7jP28mTgQSmo130_assertion description "[Deletion of SMN1 coupled with the inability of SMN2 to compensate for the loss of SMN1 leads to spinal muscular atrophy (SMA), a leading genetic cause of infant mortality ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144429.RAd9vBqnn59Yhh-32k7SLVGcGw3pD4ZcH7jP28mTgQSmo130_provenance.
- NP144431.RAagCeWw_ujJAbNliW-I1DINhMTmXkgPfEGRC4qyEojjI130_assertion description "[We present the results of carrier studies in 33 relatives of the paternal branch of a spinal muscular atrophy patient with homozygous absence of the SMN1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144431.RAagCeWw_ujJAbNliW-I1DINhMTmXkgPfEGRC4qyEojjI130_provenance.
- NP144433.RAbIXHHrBYzs92-jFZR9sAfcJ_zBKSfqLam17hWUNRzjw130_assertion description "[spinal muscular atrophy causing missense mutations identified in this study interfere with the reported interactions of SMN ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144433.RAbIXHHrBYzs92-jFZR9sAfcJ_zBKSfqLam17hWUNRzjw130_provenance.
- NP144437.RAW_cYAb8S8at7FM9VAXEaK2UnTyfmqXVByjM6KJjKgoY130_assertion description "[quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144437.RAW_cYAb8S8at7FM9VAXEaK2UnTyfmqXVByjM6KJjKgoY130_provenance.
- NP144439.RAYSSZO-J-0Jy0P5vizKJrujx16CcFHNpgs7YbMe8NmVU130_assertion description "[Four disease-associated missense mutations in the glycyl tRNA synthetase gene in families with Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144439.RAYSSZO-J-0Jy0P5vizKJrujx16CcFHNpgs7YbMe8NmVU130_provenance.
- NP144441.RAZjWxJEIR451vlOGjuYZj6oP7qFMr0ROewU8hjGkPYWU130_assertion description "[CpG methylation of smn2 correlates with the severity of spinal muscular atrophy disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144441.RAZjWxJEIR451vlOGjuYZj6oP7qFMr0ROewU8hjGkPYWU130_provenance.
- NP144446.RAboqF5bq8c0zuIm-lpY2w1xi1ULTJNXh-Olbd2MzIASM130_assertion description "[May be a modifying factor for disease severity of spinal muscular atrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144446.RAboqF5bq8c0zuIm-lpY2w1xi1ULTJNXh-Olbd2MzIASM130_provenance.
- NP144450.RAZfEJ5_XCao15U7g-PiGiwCWOkSo0Vs6qwVIxdYBGOwA130_assertion description "[Cognitive impairment may be another feature of the MFN2-related phenotype/widespread peripheral and CNS involvement, as well as the neurosensorial defects, underline the similarities among MFN2-related and primary mitochondrial disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144450.RAZfEJ5_XCao15U7g-PiGiwCWOkSo0Vs6qwVIxdYBGOwA130_provenance.
- NP144451.RARBxE-AJHxpM5cGGLrZKgnTV16j1uck87dQIsvwdlaOc130_assertion description "[Thymidine phosphorylase deficiency has a role in causing MNGIE, an autosomal recessive mitochondrial disorder ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144451.RARBxE-AJHxpM5cGGLrZKgnTV16j1uck87dQIsvwdlaOc130_provenance.
- NP144456.RAXoCuPFPna9Z4Cc5ilieCcnKl6wCQYdrKRJkUo0106bg130_assertion description "[POLG molecular defects were found in 25% of patients with multiple mtDNA deletions and mitochondrial disease in this study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144456.RAXoCuPFPna9Z4Cc5ilieCcnKl6wCQYdrKRJkUo0106bg130_provenance.
- NP144462.RAV9cenVLNWcUL_2DwTZWRTxFtlntE_dTh46_Kbu8akpA130_assertion description "[we detected a high frequency of BORIS expression in uterine cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144462.RAV9cenVLNWcUL_2DwTZWRTxFtlntE_dTh46_Kbu8akpA130_provenance.
- NP144466.RAeADAZIMKZDebmotWdRXaa-b_q96Vv_AMRAobU6G4ysA130_assertion description "[AURKA and MDM2 were identified as interesting novel amplified genes in juvenile angiofibromas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144466.RAeADAZIMKZDebmotWdRXaa-b_q96Vv_AMRAobU6G4ysA130_provenance.
- NP144468.RAWKyoP_RfCq-LX74_zLfpWtMt80pHgHZPUOIVtAlYACA130_assertion description "[Therapeutic targeting of SPARC in nasopharyngeal angiofibroma would be targeting of a molecule at the roots of cooperation between stromatogenesis and angiogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144468.RAWKyoP_RfCq-LX74_zLfpWtMt80pHgHZPUOIVtAlYACA130_provenance.
- NP144474.RAT198fNmGkSeLN9O7pcLC_EGID2Md44Xqb7nFOZA48PA130_assertion description "[study shows uPA & uPAR are overexpressed in primary prostate cancer cells & surrounding stromal cells (Gleason score >/= 7) & more than 90% lymph node metastases but not in normal prostate, benign prostate hyperplasia or prostatic intraepithelial neoplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144474.RAT198fNmGkSeLN9O7pcLC_EGID2Md44Xqb7nFOZA48PA130_provenance.
- NP144476.RARHbmzymGXTjZh_FQCE3_VhURGq34656Bkf5svvAbR0k130_assertion description "[ANXA1 expression is decreased in prostatic adenocarcinoma and in high-grade prostatic intraepithelial neoplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144476.RARHbmzymGXTjZh_FQCE3_VhURGq34656Bkf5svvAbR0k130_provenance.
- NP144478.RAY2sk0-rgW846EYWv_WlfXPmZR5SExW8t-Ce79zP0VhY130_assertion description "[Clonal ERG rearrangements were found both in high grade prostatic intraepithelial neoplasia (PIN) and in atypical in situ epithelial lesions consistent with the diagnosis of low grade PIN.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144478.RAY2sk0-rgW846EYWv_WlfXPmZR5SExW8t-Ce79zP0VhY130_provenance.
- NP144491.RAT7zCl1Z6ikndA-KuRo5IXD9sTv4KvuJsgD7_RttkW2c130_assertion description "[the detection of isolated TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia would improve the positive predictive value of finding TMPRSS2-ERG fusion prostate cancer in subsequent biopsies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144491.RAT7zCl1Z6ikndA-KuRo5IXD9sTv4KvuJsgD7_RttkW2c130_provenance.
- NP144493.RAR7lxctJ3VHkgzER_14pA9NgMUmFX8VFUp0kPDWv34O4130_assertion description "[study shows uPA & uPAR are overexpressed in primary prostate cancer cells & surrounding stromal cells (Gleason score >/= 7) & more than 90% lymph node metastases but not in normal prostate, benign prostate hyperplasia or prostatic intraepithelial neoplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144493.RAR7lxctJ3VHkgzER_14pA9NgMUmFX8VFUp0kPDWv34O4130_provenance.
- NP144494.RARWw9rwEEtiLIoNoRsedDwMH1Asla0znSL0MNfz1ErnU130_assertion description "[low level of expression seen in prostatic intraepithelial neoplasia and prostate adenocarcinoma, suggesting lack of detoxification activity that may be associated with carcinogenesis of the prostate ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144494.RARWw9rwEEtiLIoNoRsedDwMH1Asla0znSL0MNfz1ErnU130_provenance.
- NP144497.RASG6vj_3ckplz8fYfgORrY8ybv_-IRNnlHEtD17mxTAM130_assertion description "[The total mutation rate of hMLH1 and hMSH2 gene in Chinese and Korean hereditary nonpolyposis colorectal cancer was similar and lower than that reported in Western countries/the mutation characteristics were different in the two populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144497.RASG6vj_3ckplz8fYfgORrY8ybv_-IRNnlHEtD17mxTAM130_provenance.
- NP144501.RAYZLfGsXv6YbYIu27Be5MhpsRkzkGEwtnzyEN2TAnR14130_assertion description "[Eight hMSH2 or hMLH1 gene sequence variations were found in 12 Chinese families with hereditary nonpolyposis colorectal cancer (HNPCC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144501.RAYZLfGsXv6YbYIu27Be5MhpsRkzkGEwtnzyEN2TAnR14130_provenance.
- NP144506.RAS6plsgiRYhya0CoxVFeHjyZO6Qs2boyLRgWbxLMZ5dU130_assertion description "[The first characterized nonepithelial tumors in hereditary nonpolyposis colorectal cancer seem to carry a limited panel of dna replication errors, including a frameshift at the TGFBR2 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144506.RAS6plsgiRYhya0CoxVFeHjyZO6Qs2boyLRgWbxLMZ5dU130_provenance.
- NP144507.RATqjxe-hDPzpgeiF54L07SnALSJKyzgX89V0c0BNCU0k130_assertion description "[Differential rates of frameshift alterations in four repeat sequences of hereditary nonpolyposis colorectal cancer tumors.These repeats consisted of (A) 10 in the TGF beta RII, (G) 8 in the BAX, (A) 8 in the CASP1, and (CCA) 7 in the APP genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144507.RATqjxe-hDPzpgeiF54L07SnALSJKyzgX89V0c0BNCU0k130_provenance.
- NP144522.RAR3cV2JUlIuzc5xSWXwbGIDO0NcL77koIGMznGD4inl8130_assertion description "[The researchers found three germline mutations associated with the clinical phenotype of Lynch syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144522.RAR3cV2JUlIuzc5xSWXwbGIDO0NcL77koIGMznGD4inl8130_provenance.
- NP144523.RAQDVyUtUy_sqA1-sNOZ7E5xTo4cCPdO258Bfe50gh8nI130_assertion description "[genomic rearrangements of MLH1 and MSH6 in patients suspected of hereditary nonpolyposis colorectal cancer were studied using a new interphase FISH technique ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144523.RAQDVyUtUy_sqA1-sNOZ7E5xTo4cCPdO258Bfe50gh8nI130_provenance.
- NP144525.RAb9Cqi0xEs_aBU2lcWW1LZLVMgi4xUTO_fO0XpWnY20Q130_assertion description "[Results confirmed complete exon skipping for the mutations of MLH1 in hereditary nonpolyposis colorectal cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144525.RAb9Cqi0xEs_aBU2lcWW1LZLVMgi4xUTO_fO0XpWnY20Q130_provenance.
- NP144534.RAb0CVjn22Q5r9ynpGHh6xy8Mi_VEcRJMcJrd8P5_NihY130_assertion description "[influence of Aurora-A, 91T-to-A (F31I) and 169G-to-A (V57I) polymorphisms on age of onset of hereditary nonpolyposis colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144534.RAb0CVjn22Q5r9ynpGHh6xy8Mi_VEcRJMcJrd8P5_NihY130_provenance.
- NP144536.RAS-Q7FMY0XMumyQm44U-Uopbbxw0-NC_nlX8mkjrEYEk130_assertion description "[Cytochrome P450 17A1 and catechol O-methyltransferase polymorphisms have roles in development of Lynch syndrome colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144536.RAS-Q7FMY0XMumyQm44U-Uopbbxw0-NC_nlX8mkjrEYEk130_provenance.
- NP144537.RAYQxKvLRMBFZDsQIS7a0FJzK4YXV93PiTdYau8_Ft2H8130_assertion description "[Differential rates of frameshift alterations in four repeat sequences of hereditary nonpolyposis colorectal cancer tumors.These repeats consisted of (A) 10 in the TGF beta RII, (G) 8 in the BAX, (A) 8 in the CASP1, and (CCA) 7 in the APP genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144537.RAYQxKvLRMBFZDsQIS7a0FJzK4YXV93PiTdYau8_Ft2H8130_provenance.
- NP144539.RAYMh-6ikObE8bLX2bg_YAwHvx-5-xiTmCFiYLkem3OsE130_assertion description "[Heterozygous truncating mutations in PMS2 do play a role in a small subset of patients with Lynch syndrome, indicated a need for mutational analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144539.RAYMh-6ikObE8bLX2bg_YAwHvx-5-xiTmCFiYLkem3OsE130_provenance.
- NP144542.RAdYSRaWWZcbcldQDVNAw2qig1Crm05E7Y5jX3J3oWXFk130_assertion description "[Cytochrome P450 17A1 and catechol O-methyltransferase polymorphisms have roles in development of Lynch syndrome colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144542.RAdYSRaWWZcbcldQDVNAw2qig1Crm05E7Y5jX3J3oWXFk130_provenance.
- NP144544.RAU2lKsBSB3yE7edllyRx-zE-nUZ_kUFSMJ7Zm4a4dUx4130_assertion description "[mucin and MUC1 have roles in progression of hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144544.RAU2lKsBSB3yE7edllyRx-zE-nUZ_kUFSMJ7Zm4a4dUx4130_provenance.
- NP144547.RAWsrvwl0mU6UiGz_WKU-TeIjJuzCrM5PJBaz9WNrTD0U130_assertion description "[Molecular diagnostics of Slovak familial Adenomatous Polyposis Coli families revealed broad palette of mutations in crucial APC gene ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144547.RAWsrvwl0mU6UiGz_WKU-TeIjJuzCrM5PJBaz9WNrTD0U130_provenance.
- NP144549.RAU0tV64j4JETIBGiv2gMISXovZCvb4S231yRkPmnBn0k130_assertion description "[study detected 17 different truncating mutations APC in 21 of 24 Chilean familial adenomatous polyposis families; 9 of these were novel ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144549.RAU0tV64j4JETIBGiv2gMISXovZCvb4S231yRkPmnBn0k130_provenance.
- NP144552.RAcIs128dKotlmAcQUkJogZdFe8nafNsu-skIQKBTrRiA130_assertion description "[The result of approximately 10 (-5) mutations per allele per year, although higher than previous estimates, appears to be consistent with the mutational spectrum of adenomatous polyposis coli.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144552.RAcIs128dKotlmAcQUkJogZdFe8nafNsu-skIQKBTrRiA130_provenance.
- NP144557.RAdMmpoLjBMEf2auyOzxzVBQ7mwKLr5eQRFbfUHAYOlPE130_assertion description "[Results describe the crystal structure of beta-catenin in complex with a phosphorylated adenomatous polyposis coli (APC) fragment containing two 20-amino-acid repeats, whose phosphorylation could be a critical switch for APC function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144557.RAdMmpoLjBMEf2auyOzxzVBQ7mwKLr5eQRFbfUHAYOlPE130_provenance.
- NP144558.RAegt4QLPmNod8o7EuN3-UrIeqa3pdgiLLGaa26LGCZyg130_assertion description "[binding per se of beta-catenin by adenomatous polyposis coli does not require phosphorylation by GSK-3beta ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144558.RAegt4QLPmNod8o7EuN3-UrIeqa3pdgiLLGaa26LGCZyg130_provenance.
- NP144562.RAUs1Nv1iCsh9nQPJmFN91BLSNMBeM72MlpJ90f6NGsl0130_assertion description "[Alterations in adenomatous polyposis coli/beta-catenin pathway and cyclin D1 dysregulation may contribute to pathogenesis of pleuropulmonary desmoid tumors and solitary fibrous tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144562.RAUs1Nv1iCsh9nQPJmFN91BLSNMBeM72MlpJ90f6NGsl0130_provenance.
- NP144565.RAVCpLKlCYNaLQLNHYNNPYURyp7imE9VtSz_hwOZ2Sbl8130_assertion description "[germline MYH mutations (by dHPLCO) in 20 clinic-based multiple adenoma patients who were adenomatous polyposis coli (APC) mutation-negative.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144565.RAVCpLKlCYNaLQLNHYNNPYURyp7imE9VtSz_hwOZ2Sbl8130_provenance.
- NP144569.RAZDX59RV99nvHsz9J3rfwezbmJvlV4_sxvK6x3hU-Rp4130_assertion description "[loss of expression of MGMT occurs more frequently in cancer than in adenoma in both sporadic and familial adenomatous polyposis patients, and loss of expression of MGMT is associated with hypermethylation of the promoter area of MGMT gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144569.RAZDX59RV99nvHsz9J3rfwezbmJvlV4_sxvK6x3hU-Rp4130_provenance.
- NP144577.RAYiUBYWGYSNWG9TYJhP9ROfttLZAO2kzbNnM47xFL91A130_assertion description "[Familial adenomatous polyposis with adenomatous polyposis coli gene mutation at codon 1309 entails a risk of a more aggressive phenotype; early colectomy may be indicated in children harboring this gene mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144577.RAYiUBYWGYSNWG9TYJhP9ROfttLZAO2kzbNnM47xFL91A130_provenance.
- NP144578.RAYgdzUI8LzRge4-kNIqUZt78VfbqtAjFr8q7qw4uVNPc130_assertion description "[adenomatous polyposis coli gene and nuclear b-catenin may have roles in wnt-related progression of invasive urothelial carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144578.RAYgdzUI8LzRge4-kNIqUZt78VfbqtAjFr8q7qw4uVNPc130_provenance.
- NP144579.RAYpmelcuFEUwIXnQhQoR2xF7sUQO8j22dimFS9Hzrvqk130_assertion description "[Expression of the gene in members of a large pedigree with familial polyposis syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144579.RAYpmelcuFEUwIXnQhQoR2xF7sUQO8j22dimFS9Hzrvqk130_provenance.
- NP144580.RARM5hVB61C0x9HQcmx9UjakxmABmbXirHhXRq8hBm6J4130_assertion description "[adenomatous polyposis coli gene and nuclear b-catenin may have roles in wnt-related progression of invasive urothelial carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144580.RARM5hVB61C0x9HQcmx9UjakxmABmbXirHhXRq8hBm6J4130_provenance.
- NP144584.RAUKlFzL8_j3KasHBxV5sNqMhgNtN-wpjUTq5NGUFffiw130_assertion description "[first systematic evaluation of different single-base substitutions in APC at or close to splice sites at the transcript level, found in familial adenomatous polyposis patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144584.RAUKlFzL8_j3KasHBxV5sNqMhgNtN-wpjUTq5NGUFffiw130_provenance.
- NP144587.RATh8SZwKuwa8gEYaxFJAmKo4FIYRK2PIAk1LyowxukgI130_assertion description "[adenomatous polyposis coli gene and nuclear b-catenin may have roles in wnt-related progression of invasive urothelial carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144587.RATh8SZwKuwa8gEYaxFJAmKo4FIYRK2PIAk1LyowxukgI130_provenance.
- NP144588.RASDqUedg30dULLFMe9HmQAYFSv5SL6ilQjh4Mr2FL-bY130_assertion description "[Familial adenomatous polyposis/attenuated adenomatous polyposis coli can result from APC constitutive haploinsufficiency, with gene deletion being a possible cause of reduced gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144588.RASDqUedg30dULLFMe9HmQAYFSv5SL6ilQjh4Mr2FL-bY130_provenance.
- NP144589.RAVhDNZg_yBpJnW1C49CITEJ_fKs7w_ioV-LH54PhKkno130_assertion description "[Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144589.RAVhDNZg_yBpJnW1C49CITEJ_fKs7w_ioV-LH54PhKkno130_provenance.
- NP144601.RAay6LjenZf07DzHzm5zoqq0pON-tsbc4htBPVP66Urok130_assertion description "[Functional interaction between estrogen receptor (ER) s and adenomatous polyposis coli (APC) shows that APC may physically associate with ER alpha in a ligand-dependent manner and enhance estrogen-dependent transactivation of the estrogen response element.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144601.RAay6LjenZf07DzHzm5zoqq0pON-tsbc4htBPVP66Urok130_provenance.
- NP144604.RAZsoAw0eZHrieTiZLieeptkhkOJKyX0EBjGaFAQ4dNDA130_assertion description "[Mutants may be associated with neural tube defects, but associated is too weak to recommend using MTHFR for screening.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144604.RAZsoAw0eZHrieTiZLieeptkhkOJKyX0EBjGaFAQ4dNDA130_provenance.
- NP144605.RAYxTndVr_ukWfVYm1H2JRvPpbhedhFHA5zN8lK_Cc9VA130_assertion description "[In the North Indian population, the 677C-- > T allele of the MTHFR gene may be associated with the occurrence of a lower type of neural tube defects/is a possible differential role of thermolabile MTHFR at different sites of neural tube closure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144605.RAYxTndVr_ukWfVYm1H2JRvPpbhedhFHA5zN8lK_Cc9VA130_provenance.
- NP144611.RAZrpsseuyAt0H5eKRtSiLg91GN7ffaj2yz7iXXGBv39w130_assertion description "[Variants in TERC are unlikely to be a major risk factor for the most common form of human neural tube defects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144611.RAZrpsseuyAt0H5eKRtSiLg91GN7ffaj2yz7iXXGBv39w130_provenance.
- NP144614.RAShro0un0O2-hT3KPjIjIDaGNwsTGT_dt8fWxAeaBGUc130_assertion description "[Six common polymorphisms in the TCII gene do not strongly influence risk of neural tube defects in an Irish population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144614.RAShro0un0O2-hT3KPjIjIDaGNwsTGT_dt8fWxAeaBGUc130_provenance.
- NP144615.RAZ8u62duI-MHqNFW3kubwscN4M7hcsX7vTNlaazRsZfU130_assertion description "[The current identification of cis-acting elements in the PDGFRA promoter and the transcription factors that bind them, provides a new strategy for the identification of genes that are potentially involved in neural tube defects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144615.RAZ8u62duI-MHqNFW3kubwscN4M7hcsX7vTNlaazRsZfU130_provenance.
- NP144618.RAQv_erJX02hsjFil0pwS6sp0RZ_kXKD-Za85WSKTPHjo130_assertion description "[the combination of the RR genotype for RFC-1 and low RBC folate was associated with a significant 4.6-fold increase in neural tube defect risk ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144618.RAQv_erJX02hsjFil0pwS6sp0RZ_kXKD-Za85WSKTPHjo130_provenance.
- NP144619.RAdSmAalcF7cUc2T5MwbKYhn-GzomAX0nnmy9hxM1j50Q130_assertion description "[Maternal diabetes inhibits expression of embryonic genes, most notably, Pax-3, which is required for neural tube closure.oxidative stress inhibits expression of Pax-3 providing a molecular basis for neural tube defects induced by diabetic pregnancy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144619.RAdSmAalcF7cUc2T5MwbKYhn-GzomAX0nnmy9hxM1j50Q130_provenance.
- NP144622.RAeKC0QixQpoipqw4W4ZFHpvYnGm42kv7uQehxMWU_nqc130_assertion description "[Study indicates that the serum concentration of S100B in patients with neural tube defects is similar to that of normal individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144622.RAeKC0QixQpoipqw4W4ZFHpvYnGm42kv7uQehxMWU_nqc130_provenance.
- NP144635.RAfwCDyPPiJHLeMvrKwqS5gHGH6_QCJRecIdctnjhacJM130_assertion description "[Transfected into mice, implicating endothelin as a major modifying factor for cystic disease progression in human autosomal dominant polycystic kidney disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144635.RAfwCDyPPiJHLeMvrKwqS5gHGH6_QCJRecIdctnjhacJM130_provenance.
- NP144641.RAQCXZU1ErNPFZHAg6myeLapHfCzzIiPhB_NVw3v6AxQI130_assertion description "[development of the kidney may regulate the expression of PC-1, and an altered PC-1 expression may contribute to cyst formation in autosomal dominant polycystic kidney disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144641.RAQCXZU1ErNPFZHAg6myeLapHfCzzIiPhB_NVw3v6AxQI130_provenance.
- NP144643.RAYYbpTpYZ1VRqU1rLBNC9GH46uHqmiWciSLEqnICel90130_assertion description "[PC1 modulates Ca (2+) oscillations and a molecular mechanism to explain the association between abnormal Ca (2+) homeostasis and cell proliferation in autosomal dominant polycystic kidney disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144643.RAYYbpTpYZ1VRqU1rLBNC9GH46uHqmiWciSLEqnICel90130_provenance.
- NP144647.RAV878lp3OtFaP-It1O0Qrar0v36Sn_vMGtCAa50PmM0U130_assertion description "[disruption of ER luminal calcium homeostasis may contribute to the cyst phenotype in autosomal dominant polycystic kidney disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144647.RAV878lp3OtFaP-It1O0Qrar0v36Sn_vMGtCAa50PmM0U130_provenance.
- NP144650.RAel3RvZgHPiOJN26UdJzKCWZwAjVSQbd_mlFHOCeypUc130_assertion description "[Ln-5 is an important regulator of ADPKD cell proliferation and cystogenesis; Ln-5 gamma (2) chain and Ln-5-alpha (6) beta (4) integrin interaction both contribute to these phenotypic changes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144650.RAel3RvZgHPiOJN26UdJzKCWZwAjVSQbd_mlFHOCeypUc130_provenance.
- NP144651.RAeFt2OZo5cNyfyu4h9MNbRwx2359-GZUBx2mgBdIW3PY130_assertion description "[Ln-5 is an important regulator of ADPKD cell proliferation and cystogenesis; Ln-5 gamma (2) chain and Ln-5-alpha (6) beta (4) integrin interaction both contribute to these phenotypic changes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144651.RAeFt2OZo5cNyfyu4h9MNbRwx2359-GZUBx2mgBdIW3PY130_provenance.
- NP144657.RAW6pQVyqmuHYBWPioechtEj-2DX_Ok-gUIvef6AcrYtM130_assertion description "[The CC genotype could be protective in autosomal dominant polycystic kidney disease females/genotype was described to be associated with lower pulse pressure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144657.RAW6pQVyqmuHYBWPioechtEj-2DX_Ok-gUIvef6AcrYtM130_provenance.
- NP144658.RAWpKh7Z09VEH-Bnsgy34_xALqH9LI5gd6SVVaFuIbWEQ130_assertion description "[A polymorphism of the ITGA8 promoter modifies the progression of renal failure in ADPKD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144658.RAWpKh7Z09VEH-Bnsgy34_xALqH9LI5gd6SVVaFuIbWEQ130_provenance.
- NP144663.RAVQLzXgiZo_BlQq--1U0McpUFG6HjGckxMiYNkiNpIuk130_assertion description "[activity of the AP-1 components c-Jun, ATF2, and c-Fos is altered in renal cystic tissue of patients with autosomal dominant polycystic kidney disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144663.RAVQLzXgiZo_BlQq--1U0McpUFG6HjGckxMiYNkiNpIuk130_provenance.
- NP144664.RARLD3Xt6289BeUpW500jTNPO-LsFFS2GNEgVOYU-KWSc130_assertion description "[the a allele of the ecNOS gene polymorphism showed a significantly higher incidence among patients with end-stage renal failure caused by autosomal dominant polycystic kidney disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144664.RARLD3Xt6289BeUpW500jTNPO-LsFFS2GNEgVOYU-KWSc130_provenance.
- NP144669.RAYLp-5MFc0JI6y9a3a8wMYEFE0yRCjEm_ck5SCNn2srQ130_assertion description "[The abundant WNT-4 mRNA expression in Conn's adenomas and its hormonal regulation in adrenocortical cells suggest a role for WNT-4 in human adrenocortical function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144669.RAYLp-5MFc0JI6y9a3a8wMYEFE0yRCjEm_ck5SCNn2srQ130_provenance.
- NP144670.RATEBuX_XacvHdtD1z4zvmr-etKj6HC81v6GPIH1VwkXo130_assertion description "[ERbeta transcript levels were very high in all samples of adrenocortical adenoma, normal adrenal cortex and primary pigmented nodular adrenocortical disease except those for two cardinoma, whereas aromatase levels were low ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144670.RATEBuX_XacvHdtD1z4zvmr-etKj6HC81v6GPIH1VwkXo130_provenance.
- NP144672.RAT1le8fd5mZ9fE3agciqRtI6Q9oou5omudbCbo284HWM130_assertion description "[Data show that StAR mRNA was found throughout the whole adrenal cortex attached to adrenocortical adenomas, but not in the medulla.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144672.RAT1le8fd5mZ9fE3agciqRtI6Q9oou5omudbCbo284HWM130_provenance.
- NP144681.RAVhlJx7lxpl0yrmLdyIPh4CYMA4ITKmE7TGzB9v-HwVA130_assertion description "[Loss of heterozygosity on 17p13 and down-regulation of ACADVL can be used to discriminate adrenal cortex neoplasms from adrenocortical adenoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144681.RAVhlJx7lxpl0yrmLdyIPh4CYMA4ITKmE7TGzB9v-HwVA130_provenance.
- NP144682.RAb_A88Mz9VAa95dW7iAEVj48lR2pUeystO5997ktJVoQ130_assertion description "[Endogenous ADM system plays a potentially important role in the paracrine or autocrine functional control of Conn's adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144682.RAb_A88Mz9VAa95dW7iAEVj48lR2pUeystO5997ktJVoQ130_provenance.
- NP144685.RAe8CsPehZ3WlvBAPe4haAPPuXHy0vMvN1-xK8HyM6njY130_assertion description "[A family-based association study finds that the NDUFA1 gene is unlikely to harbor a major visual loss susceptibility locus for Leber hereditary optic neuropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144685.RAe8CsPehZ3WlvBAPe4haAPPuXHy0vMvN1-xK8HyM6njY130_provenance.
- NP144687.RAf6CbCk_fmpMComs4rdrIwQKzH4d-PVRhbX5JDIeg_nY130_assertion description "[Mutations in myotilin cause MFM; exon 2 of MYOT is a hotspot for mutations; peripheral neuropathy, cardiomyopathy, and distal weakness greater than proximal weakness are part of the spectrum of myotilinopathy; not all cases have a limb-girdle phenotype ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144687.RAf6CbCk_fmpMComs4rdrIwQKzH4d-PVRhbX5JDIeg_nY130_provenance.
- NP144694.RAUKTC20N4Hrd1PyOh3VQBkMoMACW76XKgb7DbhxhvIrQ130_assertion description "[The ACE I/D genotype distribution was in Hardy-Weinberg equilibrium/stratified by sex, the D allele was associated with peripheral neuropathy in females.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144694.RAUKTC20N4Hrd1PyOh3VQBkMoMACW76XKgb7DbhxhvIrQ130_provenance.
- NP144695.RATXn3-1H-e5vHrE3qUc-a3Q1FNNOVJlRBkjJChIR5z3o130_assertion description "[early onset stroke without peripheral neuropathy caused by mutation in MFN2 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144695.RATXn3-1H-e5vHrE3qUc-a3Q1FNNOVJlRBkjJChIR5z3o130_provenance.
- NP144696.RASIwAfrLiZ3ZCgXWuyZNGmR4SwvckDAvR_7F_QcbmBkM130_assertion description "[Strict control of Pou3f1 transgene expression is critical to proper myelination, and factors responsible for Pouf31 downregulation during myelination may play important roles in the development of peripheral neuropathies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144696.RASIwAfrLiZ3ZCgXWuyZNGmR4SwvckDAvR_7F_QcbmBkM130_provenance.
- NP144697.RAYJ88HO4V5lN6fxdeabKhiFCT9yMdn4ZAq32CztVWj7w130_assertion description "[salivary gland neoplasms showed a CK7+/CK20- immunoprofile ranging from 5 to 100%; squamous carcinoma showed negative CK7/20 immunoexpression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144697.RAYJ88HO4V5lN6fxdeabKhiFCT9yMdn4ZAq32CztVWj7w130_provenance.
- NP144699.RAX3EsnZKx5nHktkRt3MGv_h_OXyNsfn2z2_gnVsidsg8130_assertion description "[The Akt isoforms are required for the HGF-stimulated invasive growth of human salivary gland cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144699.RAX3EsnZKx5nHktkRt3MGv_h_OXyNsfn2z2_gnVsidsg8130_provenance.
- NP144704.RAfZy5d5QVQifkY3kHw5gh_xq3IkPZWpwIzva1S58c5eo130_assertion description "[the Int7G24A variant of the TGFBR1 gene predisposes to small cell lung cancer risk (meta-analysis) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144704.RAfZy5d5QVQifkY3kHw5gh_xq3IkPZWpwIzva1S58c5eo130_provenance.
- NP144717.RAcrPEZokbzt91aPOP2099wrTgD1fevvHN1IIKdKqGBZU130_assertion description "[Wnt and epidermal growth factor receptor signaling pathways are altered through aberrant methylation and mutation in non small cell lung cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144717.RAcrPEZokbzt91aPOP2099wrTgD1fevvHN1IIKdKqGBZU130_provenance.
- NP144724.RAcpLIdtzCLdZJcvLPK6BYHjdSaWdtXXD9jkCjbifvW4c130_assertion description "[Down-regulation of HYAL3 is associated with small cell lung cancer and glioma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144724.RAcpLIdtzCLdZJcvLPK6BYHjdSaWdtXXD9jkCjbifvW4c130_provenance.
- NP144729.RASqdmtTG6BuQMvyHbcQpiiep1b8ptXmEG8Qhj9lyM8LE130_assertion description "[Down-regulation of HYAL1 is associated with small cell lung cancer and glioma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144729.RASqdmtTG6BuQMvyHbcQpiiep1b8ptXmEG8Qhj9lyM8LE130_provenance.
- NP144733.RARO9K3BaekljUfb6nGqji_kGkcOP3f3CqPN1z8WZZq4I130_assertion description "[These results provide the first evidence of a proximal repressor region exerting a negative role on the regulation of the hNQO1 promoter in small cell lung carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144733.RARO9K3BaekljUfb6nGqji_kGkcOP3f3CqPN1z8WZZq4I130_provenance.
- NP144739.RAXwc5WV3onqPMfhio3FnHte9CkGBHESBtgeqZDim24o8130_assertion description "[Proline-rich tyrosine kinase Pyk2 is highly expressed in small cell lung cancer cells and provides a functional link between neuropeptide-induced increases in intracellular calcium ions [Ca2+]i, and tumor cell proliferation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144739.RAXwc5WV3onqPMfhio3FnHte9CkGBHESBtgeqZDim24o8130_provenance.
- NP144744.RAeag92i16julUNm_pzlgaFbk1KFUwAvezET90tJxLmvc130_assertion description "[mRNA transcripts are expressed in tumor cells of patients with small cell lung cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144744.RAeag92i16julUNm_pzlgaFbk1KFUwAvezET90tJxLmvc130_provenance.
- NP144749.RAYGIKLADQuQaoIFLZB5K8Y5jRbN31VP6BZKcneWbtwr0130_assertion description "[Increased gastrin-releasing peptide (GRP) receptor expression in small cell lung cancer cells confers sensitivity to [Arg6, D-Trp7, 9, NmePhe8]-substance P (6-11) -induced growth inhibition ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144749.RAYGIKLADQuQaoIFLZB5K8Y5jRbN31VP6BZKcneWbtwr0130_provenance.
- NP144750.RASIFDTpVJhnbn1fz4Yn-38HB8ZHFXl7yI48pYVsAeDDU130_assertion description "[mRNA transcripts are expressed in tumor cells of patients with small cell lung cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144750.RASIFDTpVJhnbn1fz4Yn-38HB8ZHFXl7yI48pYVsAeDDU130_provenance.
- NP144752.RAYXSm50UpBZKrngFY6SruHjUiV0l2CBIqtwg8XTeYP8o130_assertion description "[GPC3 is frequently expressed in noncutaneous small cell neuroendocrine carcinoma of various origins, in particular in Merkel cell carcinoma, which, in combination with CK20 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144752.RAYXSm50UpBZKrngFY6SruHjUiV0l2CBIqtwg8XTeYP8o130_provenance.
- NP144755.RAV6GlSpIzhRdoqn7nM-rFhA-9mewcyqJLc7Tw_2Q3elo130_assertion description "[a useful immunohistochemical marker of Merkel cell carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144755.RAV6GlSpIzhRdoqn7nM-rFhA-9mewcyqJLc7Tw_2Q3elo130_provenance.
- NP144763.RAUhGaZeoAUYvuinoUMr_USy71vRf1ihwQQ5I4s9ihep4130_assertion description "[Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144763.RAUhGaZeoAUYvuinoUMr_USy71vRf1ihwQQ5I4s9ihep4130_provenance.
- NP144765.RASgU1qTNqAQB6sH1FtFw79G19ctC35J4iWLtfPWwF-zM130_assertion description "[Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144765.RASgU1qTNqAQB6sH1FtFw79G19ctC35J4iWLtfPWwF-zM130_provenance.
- NP144767.RAYxti3cvRU9V_Is3cKwxcFzbnx91gSObRT7mDBMZ5qik130_assertion description "[activating mutations in the TKD domain of EGFR contribute to radiosensitivity of non-small-cell lung carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144767.RAYxti3cvRU9V_Is3cKwxcFzbnx91gSObRT7mDBMZ5qik130_provenance.
- NP144773.RATyZ2nJ0PySgRBhtQo2RoPdp3TFkc2oUemGbqCRPad4c130_assertion description "[Brain-type glycogen phosphorylase is expressed in non-small-cell lung carcinoma, particularly adenocarcinomas, and is an independent poor prognostic factor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP144773.RATyZ2nJ0PySgRBhtQo2RoPdp3TFkc2oUemGbqCRPad4c130_provenance.