Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP174345.RAQrfOUYI1HPIPAjP5Cl1zrhg1JuHjbnq3p21QDJ_l1XI130_assertion description "[The effect of DN gp130 on breast cancer in vivo was assessed with an orthotopic nude mouse model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174345.RAQrfOUYI1HPIPAjP5Cl1zrhg1JuHjbnq3p21QDJ_l1XI130_provenance.
- NP174351.RAWZ7aL6CMYV0FSHZ198DIuWCdPM6gth5EyGvEaRVzxfw130_assertion description "[The cytolytic activity stimulated with gamma IFN-modified melanomas was mediated partly by MHC-restricted cytotoxic T lymphocytes and partly by NK cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174351.RAWZ7aL6CMYV0FSHZ198DIuWCdPM6gth5EyGvEaRVzxfw130_provenance.
- NP174357.RAVJNQa6meMMMQ_oao-JxxFNXUplCGTrko8EzJHoUdLkM130_assertion description "[Seven of these were HBV DNA NAT-positive, HBsAg-negative; of these 7, 1 was NAT-positive at baseline, but negative on follow-up, and considered a false-positive, 1 had an acute infection, and 5 had chronic prevalent HBV infections, for a NAT yield of 6 in 4798 HBsAg negative donors (1:800).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174357.RAVJNQa6meMMMQ_oao-JxxFNXUplCGTrko8EzJHoUdLkM130_provenance.
- NP174360.RAXLXZQXGqvi3x1fm9HIc4KOhrVmbJfWKFHgWQTXvvPLM130_assertion description "[We investigated the expression pattern of p63 in B-cell malignancies, and evaluated the correlation between the expression of p63 and other germinal center markers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174360.RAXLXZQXGqvi3x1fm9HIc4KOhrVmbJfWKFHgWQTXvvPLM130_provenance.
- NP174361.RAbImXud99g436RKvRYgYS6saOK8RDkgu8wTLNhaN7Kqc130_assertion description "[The mutational status of the immunoglobulin heavy chain variable (IGHV) genes identifies two subsets of CLL with different outcomes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174361.RAbImXud99g436RKvRYgYS6saOK8RDkgu8wTLNhaN7Kqc130_provenance.
- NP174371.RAYG6LqJgG82WrF1MQ7azzqZNmzBMYnj9jb76WYpAueho130_assertion description "[Aberrant regulation of NF-κB has been linked to certain conditions such as cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune responses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174371.RAYG6LqJgG82WrF1MQ7azzqZNmzBMYnj9jb76WYpAueho130_provenance.
- NP174377.RAbZPeV9bsUTEpO_KoRjAjc-CXjketGBirqGJoGoypwe4130_assertion description "[Our results indicate that the production of chimeric AML1-MTG8 protein, probably a chimeric transcription factor, may contribute to myeloid leukemogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174377.RAbZPeV9bsUTEpO_KoRjAjc-CXjketGBirqGJoGoypwe4130_provenance.
- NP174384.RAaoQ9Zsr239y984xVqarPcz_WD3pE6uaRDzdOIaEuw6w130_assertion description "[Interestingly, knockdown of TP53 and expression of K-Ras(V12) in +7 HCECs resulted in the emergence of trisomy 20, another nonrandom aneuploidy observed in ∼85% of CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174384.RAaoQ9Zsr239y984xVqarPcz_WD3pE6uaRDzdOIaEuw6w130_provenance.
- NP174397.RAUJrNpiZBTzJnotI_oGhXA_AOoUC1O0zKBkmtOwK4H3I130_assertion description "[These findings suggest that combined loss of p19Arf and Rag1 results in B-cell precursor leukemia in mice and may contribute to the progression of precursor B-ALL in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174397.RAUJrNpiZBTzJnotI_oGhXA_AOoUC1O0zKBkmtOwK4H3I130_provenance.
- NP174399.RARRVXIBKLYHqoYZ27qK87SrNoPeZtGnx9QBOYnmZqlGE130_assertion description "[PD patients with GBA mutations more frequently had bradykinesia as the presenting symptom and levodopa-induced dyskinesias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174399.RARRVXIBKLYHqoYZ27qK87SrNoPeZtGnx9QBOYnmZqlGE130_provenance.
- NP174403.RAQEt3V6hJTtPEoO71AOv5KptIiCgv9jE-T1DSy4YQyks130_assertion description "[A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174403.RAQEt3V6hJTtPEoO71AOv5KptIiCgv9jE-T1DSy4YQyks130_provenance.
- NP174407.RAR3-v0ZhV0W1xYhR--sBXFqb53tFguBwiNK8E-IumXj4130_assertion description "[The TP and the OPRT mRNA levels did not differ significantly between HCC and adjacent liver.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174407.RAR3-v0ZhV0W1xYhR--sBXFqb53tFguBwiNK8E-IumXj4130_provenance.
- NP174408.RAW40AxarLZS0mA4gQMDmtH_47BcwpFz35UFNUDsBDjKA130_assertion description "[The CSF was normal and haematological and biochemical tests failed to reveal a metabolic disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174408.RAW40AxarLZS0mA4gQMDmtH_47BcwpFz35UFNUDsBDjKA130_provenance.
- NP174414.RAZCGj8Xhqn0QltrumuImiUwrrtkcwenJMuBUfybIoJeI130_assertion description "[The hSNF5/INI1 gene, which encodes a subunit of the SWI/SNF family of chromatin-remodeling complexes and is located at 22q11.2, has been reported as a tumor suppressor gene inactivated in malignant rhabdoid tumors (MRTs).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174414.RAZCGj8Xhqn0QltrumuImiUwrrtkcwenJMuBUfybIoJeI130_provenance.
- NP174428.RARqiP79z-LdQE9-51JseiW444oyt5mCXdfKTK6HirIM4130_assertion description "[A study was undertaken to use an extensively optimised real-time polymerase chain reaction (PCR) using primers designed to hybridise with the P. jirovecii heat shock protein 70 (HSP70) gene to quantify P. jirovecii DNA in bronchoalveolar lavage (BAL) fluid from HIV-infected patients with and without PCP, and to compare this assay with conventional PCR targeting the P. jirovecii mitochondrial large subunit rRNA gene sequence (mt LSU rRNA).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174428.RARqiP79z-LdQE9-51JseiW444oyt5mCXdfKTK6HirIM4130_provenance.
- NP174429.RAa7DqxWo107qw32SKofSux_X8pgb9UdzdboqMCXKTH-o130_assertion description "[Caspase 9-1263AG genotype was also observed to be significantly associated with reduced risk with high-risk non-muscle-invasive bladder cancer (NMIBC) (TaG(2-3), T1G(1-3)) and invasive tumors (T2 +) of BC (P = 0.042, OR = 0.39 and P = 0.013, OR = 0.028 respectively).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174429.RAa7DqxWo107qw32SKofSux_X8pgb9UdzdboqMCXKTH-o130_provenance.
- NP174437.RAT25cIV4T-UqOVxqezlKvbA_2EzAKtpkDbG4QMe4PUls130_assertion description "[Moreover, the PCA3 score was significantly higher in men with high-grade prostate intraepithelial neoplasia (HGPIN) versus those without HGPIN, clinical stage T2 versus T1, Gleason score >or=7 versus <7, and `significant` versus `indolent` (clinical stage T1c, PSA density [PSAD] <0.15ng/ml, Gleason score in biopsy <or=6, and percent positive cores <or=33%) pCA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174437.RAT25cIV4T-UqOVxqezlKvbA_2EzAKtpkDbG4QMe4PUls130_provenance.
- NP174438.RAQFsmPmM104LLP9iFlF463FhLmcXOJ2NLins6jMt0i2A130_assertion description "[We examined estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants in relation to the risk of osteoporotic fracture, BMD, and bone geometry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174438.RAQFsmPmM104LLP9iFlF463FhLmcXOJ2NLins6jMt0i2A130_provenance.
- NP174439.RAcJGe9IMWBd4OW79VNRoP1Q846ssKQ-U1inisOdvvQ-A130_assertion description "[Among carriers of the apoE epsilon4 allele, lipoprotein(a) was associated with a progressive, age-dependent increased risk for late-onset Alzheimer disease (odds ratio for patients >80 years of age, 6.0 [95% CI, 1.2 to 30.8]; P<0.01).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174439.RAcJGe9IMWBd4OW79VNRoP1Q846ssKQ-U1inisOdvvQ-A130_provenance.
- NP174442.RAWiik-zkX-R7jUIirDFk8_V5HKN5HHYrYo-UTF-mNk2k130_assertion description "[Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174442.RAWiik-zkX-R7jUIirDFk8_V5HKN5HHYrYo-UTF-mNk2k130_provenance.
- NP174444.RAdWxz5o483sRb7iK0alhpPgOnMjyxoPF3Mx91DcA4WfM130_assertion description "[The ability of a commercially available APC-resistance assay kit to detect APC resistant FVIII was tested by reconstituting FVIII deficient plasma with the APC resistant mutants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174444.RAdWxz5o483sRb7iK0alhpPgOnMjyxoPF3Mx91DcA4WfM130_provenance.
- NP174454.RAd25BN69VGYmEnAqWqzL0_cXL0sRlGVG3PTMJg3TlgVA130_assertion description "[The PTS locus was widespread in isolates from hospital outbreaks of infection (84.2%) and nonoutbreak clinical infections (66.0%) but absent from human commensal isolates.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174454.RAd25BN69VGYmEnAqWqzL0_cXL0sRlGVG3PTMJg3TlgVA130_provenance.
- NP174456.RAd6V816hKb7ip03d8DlX2Ct9rjP7_zwifDPFQ0UdFD-o130_assertion description "[We have previously described a preimplantation genetic diagnosis (PGD) for DM using polymerase chain reaction (PCR) followed by conventional analysis on ethidium bromide-stained gels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174456.RAd6V816hKb7ip03d8DlX2Ct9rjP7_zwifDPFQ0UdFD-o130_provenance.
- NP174458.RAVbh0f1nDNlaOaHWjcCdYMCKnapSZZSAO04I3zWLU-cI130_assertion description "[Interestingly, the XP/CS patient's cells exhibited a reduced but well detectable XPD protein expression compared with hardly detectable XPD expression of the TTD patient's cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174458.RAVbh0f1nDNlaOaHWjcCdYMCKnapSZZSAO04I3zWLU-cI130_provenance.
- NP174459.RAbo0mpsdfyHvDhnbmsW45A5dKPe8ooGb1n8KPO28qaoY130_assertion description "[Due to promising results of preclinical studies investigating the PI3K/AKT pathway in grade IV brain tumors like glioblastoma and medulloblastoma, the components of this pathway have emerged as promising therapeutic targets to treat these malignant brain tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174459.RAbo0mpsdfyHvDhnbmsW45A5dKPe8ooGb1n8KPO28qaoY130_provenance.
- NP174474.RAVayYxGK2DJsxoXhJGS1uvRPW8_VPCANt1BaSYpNdjZc130_assertion description "[Due to promising results of preclinical studies investigating the PI3K/AKT pathway in grade IV brain tumors like glioblastoma and medulloblastoma, the components of this pathway have emerged as promising therapeutic targets to treat these malignant brain tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174474.RAVayYxGK2DJsxoXhJGS1uvRPW8_VPCANt1BaSYpNdjZc130_provenance.
- NP174477.RAcZBwJxd7zVvResy2Ex88X1NR0ojQMjQYB7Qa6qf0d2I130_assertion description "[These results suggest that pendrin may play a role in thyroid hormone production as the apical porter of chloride/iodide and investigation of pendrin leads to a better understanding of functional aspects of the iodine transportation system in thyroid diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174477.RAcZBwJxd7zVvResy2Ex88X1NR0ojQMjQYB7Qa6qf0d2I130_provenance.
- NP174481.RATfmZc9HHNq1anyumDVD0yyBKCzQEd_psWmH9_B-ShIk130_assertion description "[MAL promoter hypermethylation as a novel prognostic marker in gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174481.RATfmZc9HHNq1anyumDVD0yyBKCzQEd_psWmH9_B-ShIk130_provenance.
- NP174482.RAWai16Xu4UnXsDeWeiEGvOFnFDXO7Tyfn3QPLq9NQjRc130_assertion description "[Early steps in DNA damage dependent activation of the pathway are governed by monoubiquitylation of FANCD2 and FANCI by the intrinsic FA E3 ubiquitin ligase, FANCL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174482.RAWai16Xu4UnXsDeWeiEGvOFnFDXO7Tyfn3QPLq9NQjRc130_provenance.
- NP174488.RAQ1rVpQmTqRBtxvWwddcyZIyqyp3t6mk5hc0YPfKsFJI130_assertion description "[To further evaluate the implication of MMR defects in leukemogenesis, we have studied a series of 98 children with acute lymphoblastic leukemia and 14 leukemic cell lines using several indicators of MMR defects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174488.RAQ1rVpQmTqRBtxvWwddcyZIyqyp3t6mk5hc0YPfKsFJI130_provenance.
- NP174491.RATWLbraqqO0vrN6lD4sHTOLWDioMtbVJbMUaOiz-9R6M130_assertion description "[The increase of D-2-HG in SSADH deficiency can be explained by the action of hydroxyacid-oxoacid transhydrogenase, a reversible enzyme that oxidases GHB in the presence of 2-ketoglutarate yielding SSA and D-2-HG.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174491.RATWLbraqqO0vrN6lD4sHTOLWDioMtbVJbMUaOiz-9R6M130_provenance.
- NP174502.RAQve0X5xR5fJLZI-QFwA4zX9n4tH6Nky-Dg9mX0xsoVY130_assertion description "[Compared to controls and 354 background/alignment markers, AD brain showed a generalized depression in brain gene transcription, including decreases in RNA encoding transcription factors (TFs), neurotrophic factors, signaling elements involved in synaptic plasticity such as synaptophysin, metallothionein III, and metal regulatory factor-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174502.RAQve0X5xR5fJLZI-QFwA4zX9n4tH6Nky-Dg9mX0xsoVY130_provenance.
- NP174506.RAbeAN3QzhrxQpfCFRM6fSU3ks3U4qIPGFhRpvyC60aX4130_assertion description "[Further studies confirmed that Notch-1 inhibition decreased EGFR messenger RNA (mRNA) and EGFR protein in glioma and other cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174506.RAbeAN3QzhrxQpfCFRM6fSU3ks3U4qIPGFhRpvyC60aX4130_provenance.
- NP174511.RAacaeLUuQXBWXVhg4ELQmBcWwX82u2MWh3M2tORBiRjI130_assertion description "[Importantly, knockdown IL-6 reduced VEGF expression and abolished osteosarcoma conditional medium-mediated angiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174511.RAacaeLUuQXBWXVhg4ELQmBcWwX82u2MWh3M2tORBiRjI130_provenance.
- NP174512.RAXtM07hIHEHko2BgEvMqgnR5KxgAbl6nguhGjzMG8VNM130_assertion description "[Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a promising therapeutic target for treating coronary heart disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174512.RAXtM07hIHEHko2BgEvMqgnR5KxgAbl6nguhGjzMG8VNM130_provenance.
- NP174520.RAZIUAJ-w_spz94dNNRxiGahkjU4xOGJ-1g833fSgGw20130_assertion description "[HIF-1 alpha protein expression in LPS-stimulated THP-1 macrophages could be blocked by ERK- and PI3K-inhibitors, but also by the CaMKII inhibitor KN93.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174520.RAZIUAJ-w_spz94dNNRxiGahkjU4xOGJ-1g833fSgGw20130_provenance.
- NP174521.RAeMO98L1rNv_aqVNoi25585LWU0MsOmSLlrAEZmSGu6s130_assertion description "[CpG methylation-dependent silencing of SFRP1, SFRP2 and SFRP5 was frequently seen among GC cell lines (SFRP1, 16/16, 100%; SFRP2, 16/16, 100%; SFRP5, 13/16, 81%) and primary GC specimens (SFRP1, 42/46, 91%; SFRP2, 44/46, 96%; SFRP5, 30/46, 65%), and treatment with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine rapidly restored SFRP expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174521.RAeMO98L1rNv_aqVNoi25585LWU0MsOmSLlrAEZmSGu6s130_provenance.
- NP174528.RAaRGfYAO88ZgsE-3ViB8Wxo_PeGHAEw9dXSwpL1TkjVc130_assertion description "[Cancer-associated fibroblasts (CAF) have been implicated in promoting tumor development and have been associated with mesenchymal stem cells (MSC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174528.RAaRGfYAO88ZgsE-3ViB8Wxo_PeGHAEw9dXSwpL1TkjVc130_provenance.
- NP174531.RAdc5A4tEUzQ7QbYxZr7n1jYaS19nHXutkNYtvGZ73m84130_assertion description "[The degree of agreement between the biopsy and surgical sites was high for APC LOH, MSI, and KRAS mutations (kappa=0.85, 1.00, and 0.93, respectively) but less so for DCC LOH (kappa=0.62).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174531.RAdc5A4tEUzQ7QbYxZr7n1jYaS19nHXutkNYtvGZ73m84130_provenance.
- NP174534.RAZrCO0zrqwW0QYHA-iNgH-H_6wLOyMaePHGA_bJ1P5Rg130_assertion description "[In the present study, the -48A/G polymorphism of the DRD1 gene was estimated in patients with schizophrenia (n=407) or bipolar affective disorder (n=380), and in healthy controls (n=399).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174534.RAZrCO0zrqwW0QYHA-iNgH-H_6wLOyMaePHGA_bJ1P5Rg130_provenance.
- NP174545.RAWrABoA035GVVcBOis7ZUQ4gipF2u1TpIyiN0AsPS-RA130_assertion description "[In some pathological conditions such as B-chronic lymphocytic leukemia, the CD23 gene is abnormally regulated resulting in CD23 overexpression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174545.RAWrABoA035GVVcBOis7ZUQ4gipF2u1TpIyiN0AsPS-RA130_provenance.
- NP174549.RAeGbKxDdN7t6ogIaMRDRGODgwcax1kysQWsYe4h5JGzc130_assertion description "[Coding variants of SCN2A, SCN8A, and SCN9A have also been identified in patients with seizures, ataxia, and sensitivity to pain, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174549.RAeGbKxDdN7t6ogIaMRDRGODgwcax1kysQWsYe4h5JGzc130_provenance.
- NP174554.RATTuFi-YDL1-4PShSOzm0tkI9Qx4DtXxgXOYXC7dONe8130_assertion description "[Collectively, results reveal the involvement of LEDGF-mediated elevated expression of Hsp27-dependent survival pathway(s) in PC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174554.RATTuFi-YDL1-4PShSOzm0tkI9Qx4DtXxgXOYXC7dONe8130_provenance.
- NP174555.RAVM5n57_qnXgKHVLx7kQ5wJCzaqD0rmQhsND03SW4x3w130_assertion description "[We determined the frequency of ATM IVS10-6T-->G variants in a cohort of individuals affected by breast and/or ovarian cancer who underwent BRCA1 and BRCA2 genetic testing at four major Australian familial cancer clinics.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174555.RAVM5n57_qnXgKHVLx7kQ5wJCzaqD0rmQhsND03SW4x3w130_provenance.
- NP174556.RAYRyKVJ1YKAOBZo25sEj0BUkL7isUtlN2z-3h8wIrge0130_assertion description "[Our findings confirm the synergism between MEN1 gene mutations and subsequent MEN1 allelic losses in the tumorigenesis of MEN1-associated adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174556.RAYRyKVJ1YKAOBZo25sEj0BUkL7isUtlN2z-3h8wIrge0130_provenance.
- NP174564.RAchQrQhjS97Q4OuWhV-Q0ujNn-lYF3E87CfOuOfDkCaI130_assertion description "[An adenovirus infection assay was performed in two cell lines that were established from CAR-positive osteosarcoma tissue and CAR-negative malignant fibrous histiocytoma tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174564.RAchQrQhjS97Q4OuWhV-Q0ujNn-lYF3E87CfOuOfDkCaI130_provenance.
- NP174565.RAd3ek2isjzduKhKhlFnbWlMXN3lbapR3SyTw0Vz_7E0A130_assertion description "[MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174565.RAd3ek2isjzduKhKhlFnbWlMXN3lbapR3SyTw0Vz_7E0A130_provenance.
- NP174570.RAa1lSJiwz_Y95FkrGyLKuY8vVusoEX7keQsA4A_Ruge0130_assertion description "[Zip6 (LIV-1) over-expression has been documented in estrogen receptor-positive (ER+) breast tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174570.RAa1lSJiwz_Y95FkrGyLKuY8vVusoEX7keQsA4A_Ruge0130_provenance.
- NP174571.RAa4D7xZEn7OmQ19ZTWwAVNrvZpSae3LNdHVeCDkOsBYA130_assertion description "[We assessed the association between polymorphisms in the HSD11B1 gene and left ventricular mass (LVM) in 248 families ascertained through a proband with hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174571.RAa4D7xZEn7OmQ19ZTWwAVNrvZpSae3LNdHVeCDkOsBYA130_provenance.
- NP174574.RASyCyPWhWjRkeA_fx5Byc2kleDy1ExXxYDlaLG8hWvKQ130_assertion description "[COX-2 expression induction by various combinations of chenodeoxycholate and acidity was observed by Western blotting and reverse transcriptase-polymerase chain reaction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174574.RASyCyPWhWjRkeA_fx5Byc2kleDy1ExXxYDlaLG8hWvKQ130_provenance.
- NP174576.RAbVVJDb2yQeAsRrgoZNbRPe17_sD-gj20pxO6Yu7exx0130_assertion description "[Additionally, SNX-2112 prolonged the survival time of NOD/SCID mice inoculated with K562 tumor cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174576.RAbVVJDb2yQeAsRrgoZNbRPe17_sD-gj20pxO6Yu7exx0130_provenance.
- NP174579.RAXViWGUNO6QqMfY00JORQyF1ykjTZdVxe9mrwht_5geQ130_assertion description "[CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174579.RAXViWGUNO6QqMfY00JORQyF1ykjTZdVxe9mrwht_5geQ130_provenance.
- NP174583.RAb6HkJ7qm9OL-Juvx5WFPrzoZtVJJiAqx4ELqhopKdKk130_assertion description "[We investigated the prognostic significance of a new method of mitotic figure quantitation, 'mitotic percentage index' (MPI), tumour S phase fraction (SPF) and DNA ploidy measured by flow cytometry, and various clinical prognostic factors including age, sex, tumour stage, degree of surgical resection, radiotherapy dose and adjuvant chemotherapy in 70 cases of childhood medulloblastoma diagnosed between 1968 and 1996.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174583.RAb6HkJ7qm9OL-Juvx5WFPrzoZtVJJiAqx4ELqhopKdKk130_provenance.
- NP174584.RASxjSfXQfHEvqRTZdWyJ3K3I3sq1OFT_psY4ySNrw5fE130_assertion description "[The occurrence of HPE and the DWM in both of these patients suggests that, in addition to ZIC2, which is important for normal development of the forebrain, there is at least one other dosage-sensitive gene in 13q22-q33 that plays an important role in brain development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174584.RASxjSfXQfHEvqRTZdWyJ3K3I3sq1OFT_psY4ySNrw5fE130_provenance.
- NP174586.RAc0SeSA-JN7ygVeXYhIPH4i5g24rlt4-hhbD2i4MbxUM130_assertion description "[Intestinal biopsies and concurrently collected sera from patients with Crohn's disease (CD) and Ulcerative colitis (UC) enrolled in the Swiss IBD cohort study were analyzed for intestinal TREM-1 mRNA and serum sTREM-1 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174586.RAc0SeSA-JN7ygVeXYhIPH4i5g24rlt4-hhbD2i4MbxUM130_provenance.
- NP174588.RAdyfOsKwExYsPUV6KJfkt0BzzcqUaOdWof8sFuA5YISQ130_assertion description "[The sensitivity (Se), specificity (Sp), and positive and negative predictive values (PPV and NPV, respectively) of GMA for IA were 88.2%, 95.8%, 75%, and 98.3%, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174588.RAdyfOsKwExYsPUV6KJfkt0BzzcqUaOdWof8sFuA5YISQ130_provenance.
- NP174590.RAT_cxB1xWi1wduwJsL5hq_YPYpZ6dXmda4w8PUyGVOG4130_assertion description "[The arthritogenic peptide hypothesis has inspired research aimed at defining the peptide-presenting properties of HLA-B27 subtypes and their relation to ankylosing spondylitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174590.RAT_cxB1xWi1wduwJsL5hq_YPYpZ6dXmda4w8PUyGVOG4130_provenance.
- NP174595.RAU0KCSLuNSEp-VDbD4V6q3ftSBhaK4pbX7Qu1uCvCFrs130_assertion description "[Decreased expression of REPS2/POB1 during progression of prostate cancer may therefore result in loss of control of growth factor signalling and consequently in loss of control of cell proliferation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174595.RAU0KCSLuNSEp-VDbD4V6q3ftSBhaK4pbX7Qu1uCvCFrs130_provenance.
- NP174597.RAS1NE9TWKLPe7etF_r3WmzhnlrTnKz4zk2eXvCB035Do130_assertion description "[Recurrent mutations were detected in 41 genes not yet implicated in medulloblastoma; several target distinct components of the epigenetic machinery in different disease subgroups, such as regulators of H3K27 and H3K4 trimethylation in subgroups 3 and 4 (for example, KDM6A and ZMYM3), and CTNNB1-associated chromatin re-modellers in WNT-subgroup tumours (for example, SMARCA4 and CREBBP).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174597.RAS1NE9TWKLPe7etF_r3WmzhnlrTnKz4zk2eXvCB035Do130_provenance.
- NP174602.RAf8Wb36PbjA4KPidw-ZqjcYtRytuzhN5_f7LUAoMszy4130_assertion description "[The present study demonstrates that DZNep induces robust apoptosis in AML cell lines, primary cells, and targets CD34(+)CD38(-) leukemia stem cell (LSC)-enriched subpopulations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174602.RAf8Wb36PbjA4KPidw-ZqjcYtRytuzhN5_f7LUAoMszy4130_provenance.
- NP174604.RAY2v3uR3faGoOeQYtXEMafhtuBncN4aHvBq7-XC4KID8130_assertion description "[Both splits also distinguish each of the two DR3-bearing extended haplotypes (HLA-B8,SCO1,DR3,DQw2,Dw24 and B18,F1C30,DR3,DQw2,Dw25) found associated to several autoimmune diseases as insulin-dependent diabetes mellitus (IDDM), systemic lupus erythematosus (SLE) and myasthenia gravis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174604.RAY2v3uR3faGoOeQYtXEMafhtuBncN4aHvBq7-XC4KID8130_provenance.
- NP174606.RAXJGBxPMhN4TGGNfEu7ymsl9AZgDG_RUF6ZN6NDjhaMg130_assertion description "[To clarify the association between functional polymorphisms in two other inflammatory cytokine genes [tumour necrosis factor (TNF)-alpha and interleukin (IL)-2] and the severity of autoimmune thyroid disease (AITD), we examined the TNF-alpha-1031T/C, TNF-alpha-857C/T and IL-2 -330T/G polymorphisms in genomic DNA samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174606.RAXJGBxPMhN4TGGNfEu7ymsl9AZgDG_RUF6ZN6NDjhaMg130_provenance.
- NP174614.RATjp8DTsuR5dl595HJW5BRnMqf3FlMspJxaKV6qVCoHI130_assertion description "[This investigation compares the epidemiology of DSM-III-defined alcohol abuse and addiction in DIS-based population surveys cross-nationally (in St Louis, Mo; Edmonton, Canada; Puerto Rico; Taipei City, Taiwan; and South Korea).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174614.RATjp8DTsuR5dl595HJW5BRnMqf3FlMspJxaKV6qVCoHI130_provenance.
- NP174619.RAUVtbn-WJD8-XMC3_pqpq9Q3NW4M2xE5zkCl7LKNViMA130_assertion description "[These data establish a functional role for IRF-1 in the growth suppression of breast cancer cells and strongly implicate IRF-1 as a tumor suppressor gene in breast cancer that acts, independent of p53, to control apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174619.RAUVtbn-WJD8-XMC3_pqpq9Q3NW4M2xE5zkCl7LKNViMA130_provenance.
- NP174629.RAfBj_LBN8ao-zNjzk2mtcJmwkhT7lijFCUZNE-rY5ees130_assertion description "[These results point out the importance of EGFRvIII, IL-13Ralpha2 and, to a less extent gp100 and TRP-2, for developing an immunotherapy strategy against glioblastoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174629.RAfBj_LBN8ao-zNjzk2mtcJmwkhT7lijFCUZNE-rY5ees130_provenance.
- NP174630.RAWZRt8Bt7mYDe8ShX84inydHfgrSuh9-FyN8njxfyOlI130_assertion description "[Fifteen patients with pHPT and eight with PETs agreed to MEN1 gene mutation analysis, which was performed by single-strand conformational variant analysis and direct DNA sequencing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174630.RAWZRt8Bt7mYDe8ShX84inydHfgrSuh9-FyN8njxfyOlI130_provenance.
- NP174632.RAUPHc7clCZoo1V2sfqtVbJY--olR40JIi3Cnuy1JesFI130_assertion description "[In conclusion, by combining the whole-genome DNA methylation pattern and the gene expression profile, we identified the six genes (CCDC37, CYTL1, CDO1, SLIT2, LMO3, and SERPINB5) that are regulated by DNA methylation, and we suggest their value as target molecules for further study of SCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174632.RAUPHc7clCZoo1V2sfqtVbJY--olR40JIi3Cnuy1JesFI130_provenance.
- NP174645.RATGbGnKWqq3FgnQs_q5_ecbdUsk0ywalGw8307ZHdBb8130_assertion description "[This suggests that the absence of an alternative ATG codon in the vicinity of a TIC increases the likelihood that a given TIC mutation will come to clinical attention.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174645.RATGbGnKWqq3FgnQs_q5_ecbdUsk0ywalGw8307ZHdBb8130_provenance.
- NP174649.RASBCH3tKio9cVGZUgtswrc9j-_y4I3Y6N8kGgaYCKScA130_assertion description "[In this study, we evaluated the relationship between two MT2A polymorphisms (-209 and + 838 locus), metal status, and inflammatory/immune response in older patients with CS only (the CS1 group) or with CS and previous cerebrovascular episodes (transient ischemic attack or stroke) (the CS2 group).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174649.RASBCH3tKio9cVGZUgtswrc9j-_y4I3Y6N8kGgaYCKScA130_provenance.
- NP174659.RAf_wPwjXE3p2dKB1U1C7EI3gv2k7iHnfDir4wtvyrYbI130_assertion description "[We describe a Sicilian family presenting a recessive form of hypercholesterolemia harboring a mutation of the autosomal recessive hypercholesterolemia (ARH) gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174659.RAf_wPwjXE3p2dKB1U1C7EI3gv2k7iHnfDir4wtvyrYbI130_provenance.
- NP174660.RAZMt9NgPTg6qoBvC5a-xKc7hn6l4BM58pSeHxRSlvQrI130_assertion description "[The mean polymerase chain reaction product intensities were significantly less in the basal cell carcinoma as compared with the normal human epidermal keratinocytes at the following levels: p < 0.001 for alpha6 and beta4 integrins and the beta3 chain of laminin 5; p < 0.01 for BPAG1; and p < 0.05 for BPAG2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174660.RAZMt9NgPTg6qoBvC5a-xKc7hn6l4BM58pSeHxRSlvQrI130_provenance.
- NP174663.RAYv2Tlp6wSu4w8efoeJsUe5fCW3zb1vy2p9sBAut6bpU130_assertion description "[The t(2;5) (p23;q35) chromosomal translocation has been found in a high proportion of lymph node-based CD30+ large cell lymphomas of T-cell lineage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174663.RAYv2Tlp6wSu4w8efoeJsUe5fCW3zb1vy2p9sBAut6bpU130_provenance.
- NP174669.RAUUL0C1GkT7bepgVsASSsPOC4lB7LOoRfF1mXHzxkoZc130_assertion description "[Triple diabetes: coexistence of type 1 diabetes mellitus and a novel mutation in the gene responsible for MODY3 in an overweight adolescent.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174669.RAUUL0C1GkT7bepgVsASSsPOC4lB7LOoRfF1mXHzxkoZc130_provenance.
- NP174670.RAZOJoeelDmZsx0beUxKq24JRPslPmbT1YzrkFDul7bqY130_assertion description "[We have generated variant forms of the Tpr-Met oncoprotein with the ability to bind individually to the p85 subunit of PI3'K, PLCgamma, or to the Grb2 or Shc adaptor proteins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174670.RAZOJoeelDmZsx0beUxKq24JRPslPmbT1YzrkFDul7bqY130_provenance.
- NP174673.RAW4xQxWi5K0Ro1ICHsFa14jNTzmW59FyeCIKgSKCTjBk130_assertion description "[Heterozygous mutations in the IGF1 receptor (IGF1R) gene lead to partial resistance to IGF1 and contribute to intrauterine growth retardation (IUGR) with postnatal growth failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174673.RAW4xQxWi5K0Ro1ICHsFa14jNTzmW59FyeCIKgSKCTjBk130_provenance.
- NP174689.RAbVmq1wf1M7K3uFVTW6NMXKlMOs9vmJNSRnEDhMRmP4I130_assertion description "[The deposition of the beta amyloid peptide in neuritic plaques and cerebral blood vessels is a hallmark of Alzheimer's disease (AD) pathology.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174689.RAbVmq1wf1M7K3uFVTW6NMXKlMOs9vmJNSRnEDhMRmP4I130_provenance.
- NP174691.RARZsSoHhAR55IcZfWz3B4vhqzV1iS2Swxy8SHIYT5-oY130_assertion description "[BRAF and NRAS genotyping was performed on genomic DNA (isolated using laser capture microdissection) from dysplastic nevi ranging in severity from mild (12), to moderate (11), and to severe (11).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174691.RARZsSoHhAR55IcZfWz3B4vhqzV1iS2Swxy8SHIYT5-oY130_provenance.
- NP174693.RAfnmD0O6EkDgpLfsifF6nKdj-o66UVRl8iohOi-ka9Ic130_assertion description "[Mutations in the cyclin-dependent kinase-like 5 gene (CDKL5) have been identified in female patients with early onset epileptic encephalopathy and severe mental retardation with a Rett-like phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174693.RAfnmD0O6EkDgpLfsifF6nKdj-o66UVRl8iohOi-ka9Ic130_provenance.
- NP174702.RAdE8TsdBw_HBPNUZuGu7b_CpWn9PFGcn-JIpVRaon-G8130_assertion description "[Re-analysis in the original DFNB 17 family and additional data from a second unrelated consanguineous family with congenital deafness found to map to the interval, limited the area of shared homozygosity-by-descent (HBD) to approximately 4 megabase (Mb) between markers D7S2453 and D7S525.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174702.RAdE8TsdBw_HBPNUZuGu7b_CpWn9PFGcn-JIpVRaon-G8130_provenance.
- NP174703.RAXwOiVsBuDdWJ3x3psYLXXoG-AADhwYqc-GCZZzs4UKQ130_assertion description "[Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174703.RAXwOiVsBuDdWJ3x3psYLXXoG-AADhwYqc-GCZZzs4UKQ130_provenance.
- NP174707.RATbXQKNw7q0X3gBxLWAz_upuwaf5om4xzK8RdyYhEuCY130_assertion description "[The study's data demonstrate overexpression of KIAA0247 associates with 5-FU therapeutic benefits, and also identify the clinical significance of fecal KIAA0247 in CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174707.RATbXQKNw7q0X3gBxLWAz_upuwaf5om4xzK8RdyYhEuCY130_provenance.
- NP174722.RAQNAUIpQMkd3PSSxY_RjB-4mnUmTtde9hCSo0-LQcTvY130_assertion description "[Human urokinase-type plasminogen activator (uPA) gene administration via an adenoviral (Ad)-vector induced cirrhosis regression and ameliorated hepatic dysfunction in a model of experimental liver cirrhosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174722.RAQNAUIpQMkd3PSSxY_RjB-4mnUmTtde9hCSo0-LQcTvY130_provenance.
- NP174728.RARvdURILO1-Dhp7caKL9Zyll1Lq5_vlYbYOnQyfxojIg130_assertion description "[Although the risk of multiple sclerosis was increased with presence of one or more HLA-DRB1*15 alleles (hazard ratio [HR] 2·32, 95% CI 1·25-4·30), reduced serum 25-hydroxyvitamin D concentration (HR per 10 nmol/L decrease 1·11, 1·00-1·25), and previous Epstein-Barr-virus infection (HR 2·04, 0·99-4·20), no interactions between these variables were detected on multivariate analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174728.RARvdURILO1-Dhp7caKL9Zyll1Lq5_vlYbYOnQyfxojIg130_provenance.
- NP174729.RAYpraKiAdDPE_CbTQH00RyWKgG7KzqlnmNua7PFibWnc130_assertion description "[The phosphorylation levels of p38 and ERK1/2 in MDMs from BD patients and controls were increased following stimulation with either PGN or LPS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174729.RAYpraKiAdDPE_CbTQH00RyWKgG7KzqlnmNua7PFibWnc130_provenance.
- NP174731.RAdzxD0LTk5pl_qo3VIqtkoDv6JN4ZWnNRZvTICAxjcnA130_assertion description "[Together, these studies add a new dimension to our understanding of hPrp19, and we have reason to believe that continuing excavation of this multi-faceted protein may shed light on its roles in human diseases, especially in cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174731.RAdzxD0LTk5pl_qo3VIqtkoDv6JN4ZWnNRZvTICAxjcnA130_provenance.
- NP174732.RAdJu12hj2A-0cRxGLVkysSqXzeTHw5w2-V8nvB9ao-T8130_assertion description "[The MTHFR 677 CC genotypes had significantly higher proportions in the control group compared to the PCOS patients (χ(2) = 21.381, P < 0.001).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174732.RAdJu12hj2A-0cRxGLVkysSqXzeTHw5w2-V8nvB9ao-T8130_provenance.
- NP174734.RAdhPmZYPkxCTPeyYy3yHY5E46qdvO3sQM4iB98EpicXQ130_assertion description "[Dominant inheritance of osteogenesis imperfecta (OI) is caused by mutations in COL1A1 or COL1A2, the genes that encode type I collagen, and CRTAP, LEPRE1, PPIB, FKBP10, SERPINH1, and SP7 mutations were recently detected in a minority of patients with autosomal recessive OI.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174734.RAdhPmZYPkxCTPeyYy3yHY5E46qdvO3sQM4iB98EpicXQ130_provenance.
- NP174750.RAQ-RwOIYa8pGimyRHeeJl2j5BBlWJv92TMIP_835PNqg130_assertion description "[Here we report that BRCA1 exhibits a bona fide ubiquitin (Ub) protein ligase (E3) activity, and that cancer-predisposing mutations within the BRCA1 RING domain abolish its Ub ligase activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174750.RAQ-RwOIYa8pGimyRHeeJl2j5BBlWJv92TMIP_835PNqg130_provenance.
- NP174752.RAY27sjqSh1tM7-JgQewSOj3cxkjBvsZvtrnjQWHLMHzo130_assertion description "[In this study three variants (-1195G/A and -765G/C in the promoter and 8473C/T in 3'UTR) of COX-2 were examined for correlation with breast cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174752.RAY27sjqSh1tM7-JgQewSOj3cxkjBvsZvtrnjQWHLMHzo130_provenance.
- NP174757.RAT9AhG7aNZUKJUuCYkvMeL_z0_pBnoVv1eBAkRwWqyks130_assertion description "[Within 14 acute myeloblastic leukemia patients, we confirmed 2 cases with FLT3-internal tandem duplication+, 1 patient with AML1-ETO, and only 1 case carrying a PML-RARalpha rearrangement.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174757.RAT9AhG7aNZUKJUuCYkvMeL_z0_pBnoVv1eBAkRwWqyks130_provenance.
- NP174767.RATJ1ej8WgxIgglDlUvWiD30GUxKhIuOSW-4WhtGnfDWs130_assertion description "[Subgroup analysis showed that the 5-year survival rates were worse in FGC patients with nerve invasion, high PCNA expression, negative expression of EGFR, and positive expression of P53 than those in SGC group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174767.RATJ1ej8WgxIgglDlUvWiD30GUxKhIuOSW-4WhtGnfDWs130_provenance.
- NP174768.RAeJhzuvOgwOuIY_d60O6Q2f2908xiLpBCmlocxZo20jI130_assertion description "[Elevated numbers of primitive Philadelphia chromosome-positive (Ph+) progenitors, including long-term culture-initiating cells (LTC-IC) as well as colony-forming cells (CFC), have been previously described in the blood of patients with chronic myeloid leukemia (CML) in chronic phase with high white blood cell counts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174768.RAeJhzuvOgwOuIY_d60O6Q2f2908xiLpBCmlocxZo20jI130_provenance.
- NP174787.RAToKycj9VH2ukeY6NidNCI185D2flnh-haDg0EB_jz6s130_assertion description "[Although the role of NLRP3 in host response to pathogen associated molecular patterns and danger associated molecular patterns is well documented, its role in autoimmune diseases is less well studied.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174787.RAToKycj9VH2ukeY6NidNCI185D2flnh-haDg0EB_jz6s130_provenance.
- NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_assertion description "[Our main findings were: (i) patients with stable (n = 40) and unstable (n = 40) angina had elevated plasma levels of CXCL16 compared with controls (n = 20); (ii) low-dose simvastatin (20 mg qd, n = 15) and high-dose atorvastatin (80 mg qd, n = 9) down-regulated plasma levels of CXCL16 during 6 months of therapy; (iii) in vitro, atorvastatin significantly decreased the interleukin (IL)-1beta-mediated release of CXCL16 from PBMC and endothelial cells; (iv) attenuating effect of atorvastatin on the IL-1beta-mediated release of CXCL16 in PBMC seems to involve post-transcriptional modulation as well as down-regulation of CXCL16 release through inhibition of the protease a disintegrin and metalloproteinase 10 (ADAM10); (v) soluble CXCL16 increased the release of IL-8, monocyte chemoattractant peptide 1, and matrix metalloproteinases in vascular SMC and increased the release of IL-8 and monocyte chemoattractant peptide 1 in PBMC, with particularly enhancing effects in cells from CAD patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_provenance.
- NP174799.RAVfkmKSEhE4g5nfokbD1q8_DiPFFHtFfZ-KpL8AJEhHI130_assertion description "[Although not tumour specific, AD1 and AD2 expression was significantly more frequent in carcinomas in younger women (age ≤40 years; P < 0.001) and AD1 expression was also associated with oestrogen receptor-negative and grade 3 tumours (P < 0.05).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174799.RAVfkmKSEhE4g5nfokbD1q8_DiPFFHtFfZ-KpL8AJEhHI130_provenance.
- NP174800.RAXyoBWoOLjaW22YjHawFCDNAMlQWBh_0NqIeLsdWylN4130_assertion description "[These findings indicate that the expression of dThdPase in gastric carcinomas is related to progression and metastasis, and this enzyme affects the prognosis of some patients with the disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174800.RAXyoBWoOLjaW22YjHawFCDNAMlQWBh_0NqIeLsdWylN4130_provenance.
- NP174802.RASADwZi3_SY-OQbzP5EEBCN3-bET9OF3ipTV7ht0Rqdw130_assertion description "[Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174802.RASADwZi3_SY-OQbzP5EEBCN3-bET9OF3ipTV7ht0Rqdw130_provenance.
- NP174805.RAVKYLCcqQzqn6LpSZ0ezYB9EIQ151zao2bcN_7hP8au4130_assertion description "[This study provided the first molecular characterization of INH and RIF resistance of M. tuberculosis strains from Vietnam, and detection of the katG and rpoB mutations of the INH and RIF-resistant strains should be useful for rapid detection of the INH- and RIF-resistant strains by molecular tests.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174805.RAVKYLCcqQzqn6LpSZ0ezYB9EIQ151zao2bcN_7hP8au4130_provenance.
- NP174807.RARNRvW-L5NG72N4FmB4D0mE7e0KDJo4ZbmrsZ70qs4ss130_assertion description "[Dystrophia myotonia type 1 (DM1; Steinert's disease; myotonic dystrophy) is an autosomal dominant disorder due to a large CTG expansion in the 3'-untranslated region (UTR) of the DM protein kinase (DMPK) gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174807.RARNRvW-L5NG72N4FmB4D0mE7e0KDJo4ZbmrsZ70qs4ss130_provenance.
- NP174816.RAQyIBwhCQ9LHgetv4-XCjBYxGEddhXS7iJPb8R8Rs9oc130_assertion description "[A new germline RET mutation apparently devoid of transforming activity serendipitously discovered in a patient with atrophic autoimmune thyroiditis and primary ovarian failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP174816.RAQyIBwhCQ9LHgetv4-XCjBYxGEddhXS7iJPb8R8Rs9oc130_provenance.