Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP176320.RAVtrnbtfBTLnBgVgjiLDJbtwXOhr_NDhw2vi1fDvBVMQ130_assertion description "[Further study of anti-EGFR therapy in sarcoma should only be considered after identification of molecular abnormalities predictive of benefit.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176320.RAVtrnbtfBTLnBgVgjiLDJbtwXOhr_NDhw2vi1fDvBVMQ130_provenance.
- NP176322.RAdMK5t2qEpcmQr_jNlPi3YQbKwC1xoEB1J5rTDd3le48130_assertion description "[The activation of signal transducers and activators of transcription 3 (STAT3) has been closely linked with the proliferation, survival, invasion, and angiogenesis of hepatocellular carcinoma (HCC) and represents an attractive target for therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176322.RAdMK5t2qEpcmQr_jNlPi3YQbKwC1xoEB1J5rTDd3le48130_provenance.
- NP176323.RAfd-qkT02Dq-CZEBPwTovhpUuQKZKNYynNig1nyZ1PN0130_assertion description "[Array-based comparative genomic hybridization (CGH) was used to determine chromosomal abnormalities in 39 hepatocellular neoplasms: 12 HA, 15 atypical hepatocellular neoplasms (AHN) and 12 well-differentiated HCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176323.RAfd-qkT02Dq-CZEBPwTovhpUuQKZKNYynNig1nyZ1PN0130_provenance.
- NP176324.RAZK11Gxn7uHiDIksY_8am1chCus3AqEEPIS_m6O6D4T0130_assertion description "[Eight out of twelve genes with known functions encoded transcription factors linked to two major cellular processes; inhibition of cell growth (ATF3, ATF4, KLF4, KLF6 and ELK3) and immune response (NR4A1 and CEBPB), indicating that the earliest consequences of an adenovirus infection are growth arrest and induction of an immune response.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176324.RAZK11Gxn7uHiDIksY_8am1chCus3AqEEPIS_m6O6D4T0130_provenance.
- NP176326.RAcHo0zA26v17m4mpvragvMe2-JxYj3-okvEKtiGeGt8s130_assertion description "[Consequently, we have assessed in colon adenomas and hyperplastic polyps the methylation status of MGMT, CDKN2A, and MLH1 to determine the timing and frequency of these events in the polyp-carcinoma progression sequence and subsequently to analyze the potential for these methylated genes to be molecular markers for adenomas and hyperplastic polyps.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176326.RAcHo0zA26v17m4mpvragvMe2-JxYj3-okvEKtiGeGt8s130_provenance.
- NP176327.RAWdbKGT73uzU6SQSpRYQSSar2C52hUECpY3VSzl_mvGg130_assertion description "[Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176327.RAWdbKGT73uzU6SQSpRYQSSar2C52hUECpY3VSzl_mvGg130_provenance.
- NP176332.RAZFQSbkaqwrYR5XMZjwJjqkh2ur6r-TgdLHOEU3Tw86A130_assertion description "[Loss of chromosome arms 3p and 9p and inactivation of P16 (INK4a) in normal epithelium of patients with primary lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176332.RAZFQSbkaqwrYR5XMZjwJjqkh2ur6r-TgdLHOEU3Tw86A130_provenance.
- NP176337.RAScj-uVaQmY8kotMLLzFcOjn06sQVlUGkPIJHChx9qiQ130_assertion description "[The tissue inhibitor of metalloproteinase 3 (TIMP3) is implicated in autosomal dominant Sorsby fundus dystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176337.RAScj-uVaQmY8kotMLLzFcOjn06sQVlUGkPIJHChx9qiQ130_provenance.
- NP176343.RAbqZ1SMm2qbu78DOMSPBAfF03LtrhqWw7QxNGUKByeuI130_assertion description "[Using quantitative RT-PCR, we investigated the clinical significance of the level of mRNA expression of multidrug resistance genes (MDR1, MRP1, MRP5, LRP) in a series of 29 advanced neuroblastoma samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176343.RAbqZ1SMm2qbu78DOMSPBAfF03LtrhqWw7QxNGUKByeuI130_provenance.
- NP176356.RATyhTBQyTzKON8D9esW2GDa_YqVkCeDjX22PWu2yiBo0130_assertion description "[We analyzed human leukocyte antigen (HLA) class I and HLA-DRB1 by PCR-SSP, and compared them with those of 159 controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176356.RATyhTBQyTzKON8D9esW2GDa_YqVkCeDjX22PWu2yiBo0130_provenance.
- NP176361.RAZEuIKOHKh4eFXGy8fvsPjfjOL4a164NUd1f1oOfZ-Kk130_assertion description "[We describe here a kindred in which the propositus, being heterozygote for beta-thalassemia and the H63D mutation of the HFE gene, developed severe iron overload and in turn, chronic liver failure with portal hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176361.RAZEuIKOHKh4eFXGy8fvsPjfjOL4a164NUd1f1oOfZ-Kk130_provenance.
- NP176362.RAQPiRsmwN7x4K-YJfkYHPILJDYfR1GH2WUv8NleV8J2g130_assertion description "[Functional studies found enhanced IL-8 secretion in CD133(+) liver TICs to exhibit a greater ability to self-renew, induce tumor angiogenesis, and initiate tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176362.RAQPiRsmwN7x4K-YJfkYHPILJDYfR1GH2WUv8NleV8J2g130_provenance.
- NP176374.RAQyoTxmEagZXtNlH3cfcD3fkCmNorvvxCD6nLvrXxgRY130_assertion description "[On the other hand, the transcript was not always positive in different RNA samples from benign cases, suggesting that positive carcinomas are probably composed of clonal cell populations all expressing retTPC/PTC, whereas adenomas and adenomatous goiter comprise heterogeneous populations: both positive and negative for retTPC/PTC transcript.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176374.RAQyoTxmEagZXtNlH3cfcD3fkCmNorvvxCD6nLvrXxgRY130_provenance.
- NP176376.RAbQkpNZrTDb6Ir11F2RBftvyEIoI7-6U5FmZMQS4_n1E130_assertion description "[We measured by real-time PCR the expression of genes involved in lipid metabolism [acetyl-Coenzyme A carboxylase alpha, apolipoprotein B (APOB), diacylglycerol O-acyltransferase 2, fatty acid-binding protein 1, fatty acid synthase, microsomal triglyceride transfer protein (MTTP), peroxisome proliferator-activated receptor alpha (PPARA), peroxisome proliferator-activated receptor gamma (PPARG), protein kinase AMP-activated alpha 1 catalytic subunit (PRKAA1) and sterol regulatory element-binding transcription factor 1 (SREBF1)] in liver biopsies from patients infected with HCV genotype-1 (HCVGT1), HCVGT3 and Hepatitis B (HBV) using β-glucuronidase (GUSB) and splicing factor arginine/serine-rich 4 (SFRS4) as housekeeping genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176376.RAbQkpNZrTDb6Ir11F2RBftvyEIoI7-6U5FmZMQS4_n1E130_provenance.
- NP176381.RAeQmqQr6_vEXDxnxbq2MJOowSzcF1YOfdackb3YGF9Dg130_assertion description "[Unique and uncommon BamHI allelic restriction fragments of the Ha-ras locus have been reported in the genomes of patients with cancer and of three affected members of a familial melanoma kindred (Krontiris et al., 1986).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176381.RAeQmqQr6_vEXDxnxbq2MJOowSzcF1YOfdackb3YGF9Dg130_provenance.
- NP176387.RAaPC2pVToXfAWIaand5iopw2syr-qTtwKxM6Pvll8OA0130_assertion description "[Selective induction of endothelial P2Y6 nucleotide receptor promotes vascular inflammation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176387.RAaPC2pVToXfAWIaand5iopw2syr-qTtwKxM6Pvll8OA0130_provenance.
- NP176388.RAb8Cqj4NPHGW_XGNdAsWJ_Soii_mk98gxAi6FnMJDfcw130_assertion description "[We evaluated the safety and efficacy of Pegylated interferon alpha2b (Peg-IFN) and a fixed dose of ribavirin in the treatment of chronic hepatitis C in HIV coinfection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176388.RAb8Cqj4NPHGW_XGNdAsWJ_Soii_mk98gxAi6FnMJDfcw130_provenance.
- NP176389.RAdahX0hCcrwFQs3m1bvaqvC5z8zEkbIm_q-bUdrQMr48130_assertion description "[Recent epidemiologic studies have suggested that the growth hormone (GH)/insulin-like growth factor I axis plays an important role in human breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176389.RAdahX0hCcrwFQs3m1bvaqvC5z8zEkbIm_q-bUdrQMr48130_provenance.
- NP176391.RARnWlMopuRnRErho2D82MygFiwyh0_ZRzQR6t1csqmUs130_assertion description "[Recurrent deletions of the 20p12 region led to the localization, and ultimately to the identification of mutations in the Jagged1 gene (JAG1) in AGS patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176391.RARnWlMopuRnRErho2D82MygFiwyh0_ZRzQR6t1csqmUs130_provenance.
- NP176393.RAdZNGvOKoxEFbThCWpLc6lQ5j-opikNSbAsJL4Tw38i4130_assertion description "[Our laboratory previously described the independent isolation of the fibroblast growth factor 4 (FGF-4) gene by NIH3T3 transformation assay using DNA from a patient with CML leukemia (Lucas et al., 1994).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176393.RAdZNGvOKoxEFbThCWpLc6lQ5j-opikNSbAsJL4Tw38i4130_provenance.
- NP176401.RARCfFO4HAf-rmREXpLtLb4Itzdi1dj4aEEgGvWyth95I130_assertion description "[Analysis of the genes coding for the BRCA1-interacting proteins, RAP80 and Abraxas (CCDC98), in high-risk, non-BRCA1/2, multiethnic breast cancer cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176401.RARCfFO4HAf-rmREXpLtLb4Itzdi1dj4aEEgGvWyth95I130_provenance.
- NP176404.RAfA0A-FyLDvkrsMglwWW2090ghsVqV_1OIxZy-YquZQQ130_assertion description "[Recent findings implicating TRPM7 and TRPM2 in oxidative stress-induced neuronal death thrust these channels into the spotlight as possible therapeutic targets for neurodegenerative diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176404.RAfA0A-FyLDvkrsMglwWW2090ghsVqV_1OIxZy-YquZQQ130_provenance.
- NP176407.RAT7QyV6Kd7J_UtbOduS9cmiFkg5GGgPTssb8sCJLwWBQ130_assertion description "[Accordingly, proliferative responses of LPL-T in patients with Crohn's disease and ulcerative colitis to stimulation with CD3 MoAb plus IL-2 were examined and compared with controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176407.RAT7QyV6Kd7J_UtbOduS9cmiFkg5GGgPTssb8sCJLwWBQ130_provenance.
- NP176428.RAVmDzBVaKw_klXbG2AHdOYxTC-4WN2P40GzJjSglFfkc130_assertion description "[To evaluate the role of leukotriene B4 (LTB4) receptors in inflammatory arthritis, we investigated the expression of BLT1 and BLT2 mRNA in synovial tissues of patients with rheumatoid arthritis (RA) and osteoarthritis (OA).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176428.RAVmDzBVaKw_klXbG2AHdOYxTC-4WN2P40GzJjSglFfkc130_provenance.
- NP176429.RAerqP9y-Il_as10-Ql6VPNX4VAjoLwEzX-1bIbZ16HtA130_assertion description "[Genotypic analysis of the cells in the peripheral blood, bone marrow, lymph node, and pleural effusion showed the same rearrangement pattern of the immunoglobulin heavy chain genes consistent with a B-lymphocytic neoplasm (CLL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176429.RAerqP9y-Il_as10-Ql6VPNX4VAjoLwEzX-1bIbZ16HtA130_provenance.
- NP176434.RAXyQASL5dwe74fRmVw1rvPzNQwI36JWherzdzPLnOLQk130_assertion description "[Down-regulation of LKB1 may therefore serve as an alternative to p53 mutation to drive pancreatic cancer in vivo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176434.RAXyQASL5dwe74fRmVw1rvPzNQwI36JWherzdzPLnOLQk130_provenance.
- NP176435.RAbqb2rZ5tjdDSij3wp24p8grXOM_EiEY3NhsANcQJflU130_assertion description "[CTRP-5 was detected in adipose tissue of mice and plays a role in the context of the metabolic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176435.RAbqb2rZ5tjdDSij3wp24p8grXOM_EiEY3NhsANcQJflU130_provenance.
- NP176439.RAVPxAehLWBvQX6wMYQGAFy1nJ5Gppz03RC1sz4jcu74w130_assertion description "[To investigate these phenomena and their relationship to pluripotency and senescence, we examined the response of the TP53-competent embryonal carcinoma (EC) cell line PA-1 to etoposide-induced DNA damage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176439.RAVPxAehLWBvQX6wMYQGAFy1nJ5Gppz03RC1sz4jcu74w130_provenance.
- NP176446.RAbkYh1LNDm5zNWk44YS2A6a18T4NpsJdYIU-kkdJelk8130_assertion description "[Connexin genes expressing gap junction proteins have tumor-suppressive effects on primary cancers with certain cell specificity, but the suppressive effects on metastatic cancers are still conflicting.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176446.RAbkYh1LNDm5zNWk44YS2A6a18T4NpsJdYIU-kkdJelk8130_provenance.
- NP176448.RAbQt8phodNqejks9DvrB99PxY187YTZhFpOKbzzHnEq0130_assertion description "[Two of the 13 adenomas (15.4%) and 13 of the 24 adenocarcinomas (54.2%) showed mutation patterns and were confirmed to have frame-shift mutations at the BAX repeat site by direct sequencing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176448.RAbQt8phodNqejks9DvrB99PxY187YTZhFpOKbzzHnEq0130_provenance.
- NP176452.RAeQop8BBFDlE6Y3qQK0RwmRfC1AL8XE5kJnbkSEgnRis130_assertion description "[We identified mutations in POR, encoding P450 oxidoreductase, the obligate electron donor for these enzymes, in a woman with amenorrhea and three children with ABS, even though knock-out of POR is embryonically lethal in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176452.RAeQop8BBFDlE6Y3qQK0RwmRfC1AL8XE5kJnbkSEgnRis130_provenance.
- NP176453.RAVIxI-X52Fm-Y0cMcbffj_YvHJmxfgssTrZsSOLpzIHw130_assertion description "[We identified a novel M310V mutation in GATA4 gene that is located in the NLS region and leads to hereditary ASD in a Chinese family.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176453.RAVIxI-X52Fm-Y0cMcbffj_YvHJmxfgssTrZsSOLpzIHw130_provenance.
- NP176462.RAYoufPne7HRuBVQKh4jlVNxEUlJ-P-zpg_9eVU0xK0Is130_assertion description "[Genetic contribution of chemokine receptor 2 (CCR2) polymorphisms towards increased serum total IgE levels in Indian asthmatics.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176462.RAYoufPne7HRuBVQKh4jlVNxEUlJ-P-zpg_9eVU0xK0Is130_provenance.
- NP176464.RASolvs_POzBM9ny9g0umlIDGjhCYSei7RoCY_5qxtGf8130_assertion description "[Unlike that observed in certain Burkitt lymphoma (BL) cell lines that share the same surface phenotype (CD10+CD38+CD23-CD39-), the c-myc-transfected cells expressed lymphocyte function-associated (LFA) 1, LFA-3, and intercellular adhesion molecule 1 and grew in large clumps rather than single-cell layers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176464.RASolvs_POzBM9ny9g0umlIDGjhCYSei7RoCY_5qxtGf8130_provenance.
- NP176468.RAXQMnPM4ueCo09wiJkEbFg_A-4wtdvsSi8zdoAIxdD-Q130_assertion description "[Therefore, we studied whether MTP gene polymorphisms are associated with atherosclerosis-promoting parameters, especially metabolic profiles and endothelial function, in healthy young men.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176468.RAXQMnPM4ueCo09wiJkEbFg_A-4wtdvsSi8zdoAIxdD-Q130_provenance.
- NP176469.RARrdkIHflbFpERt-YgTz122zd4EgN2MsakHh_k2BiPRs130_assertion description "[ApoE polymorphism and predisposition to coronary heart disease in youths of different European populations. The EARS Study. European Atherosclerosis Research Study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176469.RARrdkIHflbFpERt-YgTz122zd4EgN2MsakHh_k2BiPRs130_provenance.
- NP176473.RAXNDTSkxygH3dTdsRwNfpOXvgAu0bEkFiqEY9QeOVRIo130_assertion description "[One patient with IDLL had a t(8;11)(p21;q13) and a rearranged BCL-1 locus, suggesting that this may be a variant of t(11;14)(q13;q32).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176473.RAXNDTSkxygH3dTdsRwNfpOXvgAu0bEkFiqEY9QeOVRIo130_provenance.
- NP176475.RAU2xmyKwcr_Th01V2PjPP5znz_CVx7Z26S3mqrwSP2NQ130_assertion description "[In cystic tumors of the pancreas, p53 protein overexpression and DNA aneuploidy are rare events, restricted to malignant cases, mostly mucinous cystadenocarcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176475.RAU2xmyKwcr_Th01V2PjPP5znz_CVx7Z26S3mqrwSP2NQ130_provenance.
- NP176476.RAeos4htFgCGezGTnSi9V1FRPT7TwkQNY4BVo1phiVcac130_assertion description "[VEGFA is frequently overexpressed in human colorectal cancers (CRC) and its expression correlates with tumor progression and invasiveness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176476.RAeos4htFgCGezGTnSi9V1FRPT7TwkQNY4BVo1phiVcac130_provenance.
- NP176487.RATIccSleW9u1dDKI7V64H8MSiETSmt77qbseOkCpH6XI130_assertion description "[Case patients (277 patients with pulmonary tuberculosis) and control subjects (288 household contacts) were tested by polymerase chain reaction (PCR) for polymorphisms at the promoter and the exon 1 regions of the MBL gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176487.RATIccSleW9u1dDKI7V64H8MSiETSmt77qbseOkCpH6XI130_provenance.
- NP176492.RAafotSVVFBoW31Z0FkTBSmTHC_O559Eg78oa0gnFwXpE130_assertion description "[The polymerase chain reaction (PCR) has been used to amplify sequences coding for the platelet-derived growth factor A chain (PDGFA) using mRNA populations derived from two transformed cell lines (a human osteosarcoma, U-2OS, and a human glioma, U-343) and from human umbilical vein cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176492.RAafotSVVFBoW31Z0FkTBSmTHC_O559Eg78oa0gnFwXpE130_provenance.
- NP176494.RATtxjhXXK9gn4dXew5ntXGDKJJU7bORIVDQqp7VBU87M130_assertion description "[The results in clinical samples of human esophageal cancers showed that the level of IFN-gamma was increased in tumor tissues and positively correlated with tumor progression and IRF-2 expression, whereas the level of IFNGR1 was decreased and negatively correlated with tumor progression and IRF-2 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176494.RATtxjhXXK9gn4dXew5ntXGDKJJU7bORIVDQqp7VBU87M130_provenance.
- NP176495.RAYA1Wdp6nfHfRFMl0qgFWwRl6Si6TqQMICJJQz8nyyuo130_assertion description "[However, in oncogene-positive cases (BRAF(V600E) and RET/PTC1), tumors with CNA/UPD were less frequent (5/15, 33%), whereas tumors with CNA/UPD were more frequent in oncogene-negative cases (7/10, 70%), suggesting that chromosomal aberrations may play a role in the development of PTC, especially in oncogene-negative tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176495.RAYA1Wdp6nfHfRFMl0qgFWwRl6Si6TqQMICJJQz8nyyuo130_provenance.
- NP176510.RAQssb1EOFfDUyl9k-PGyie_cp2j7BZ6Pdh2SO8i8zvm4130_assertion description "[Overall, 30% of the subjects met criteria for autistic disorder and 30% met criteria for PDD-NOS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176510.RAQssb1EOFfDUyl9k-PGyie_cp2j7BZ6Pdh2SO8i8zvm4130_provenance.
- NP176520.RASve0SVd_jaYCEVcJbNZLXcPH96bGeu5HR0ZjxV9yk8M130_assertion description "[Notably, inactivating mutations in genes encoding the catalytic and regulatory subunits of the switch/sucrose non-fermenting chromatin remodeling complex have been detected in several solid cancers: sucrose non-fermenting/switch/sucrose non-fermenting-related, matrix-associated, actin-dependent regulator of chromatin, subfamily b, member 1/Brahma-related gene 1-associated factor 47/integrase interactor 1 mutations in rhabdoid tumors; AT-rich interactive domain-containing protein 1 A/Brahma-related gene 1-associated factor 250a mutations in ovarian clear cell carcinoma, hepatocellular carcinoma and gastric adenocarcinoma; polybromo 1/Brahma-related gene 1-associated factor 180 mutations in renal clear cell carcinoma; Brahma-related gene 1/switch/sucrose non-fermenting-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 4 mutations in non-small-cell lung carcinoma and AT-rich interactive domain-containing protein 2/Brahma-related gene 1-associated factor 200 mutations in hepatocellular carcinoma and malignant melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176520.RASve0SVd_jaYCEVcJbNZLXcPH96bGeu5HR0ZjxV9yk8M130_provenance.
- NP176523.RAaLmkdIqU0a48yEI_ED7aC9RHqDEw7XHWAvn1Ktw643Q130_assertion description "[In these trials, Hp typing of 69 DM individuals and treating those with the Hp 2-2 with vitamin E prevented one myocardial infarct, stroke or cardiovascular death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176523.RAaLmkdIqU0a48yEI_ED7aC9RHqDEw7XHWAvn1Ktw643Q130_provenance.
- NP176524.RASpN5L5bjc8RxeV0E2uoOIIuWx37K2cDIKWNZiC1Xbl8130_assertion description "[The latter DNA probes and probes hybridizing to chromosomal regions, which are frequently deleted in other subtypes of non-Hodgkin lymphomas (NHL), namely 9p21/ P16(INK4A), 13q14/D13S25, and 17p13/P53 were subsequently applied to all 14 cases of HCL, but no additional abnormalities were found.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176524.RASpN5L5bjc8RxeV0E2uoOIIuWx37K2cDIKWNZiC1Xbl8130_provenance.
- NP176526.RAZp8Pzh9xNPHWKRmvBtK3KmxgzgJoarHcx3bRJHkPpRU130_assertion description "[Immunoglobulins G, M, A, and E were quantitated in members of 63 families selected for the presence of children with asthma or allergic rhinitis and compared with a larger group of healthy individuals and families.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176526.RAZp8Pzh9xNPHWKRmvBtK3KmxgzgJoarHcx3bRJHkPpRU130_provenance.
- NP176527.RAdpOsg9SNSHaZu-QJTZCUKIGi3aOR81dA3qi3sbe8f4Q130_assertion description "[The results indicate that while immunization with SFV-SIVgp160 and rgp120 did not protect against virus infection, these Env vaccines did lower the virus load in plasma and protect against the lethal SIV-PBj14 challenge.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176527.RAdpOsg9SNSHaZu-QJTZCUKIGi3aOR81dA3qi3sbe8f4Q130_provenance.
- NP176533.RAfYTBU36Oan8A_ukKgOWhv-8qprO8SNcLh7blkOy_v0Y130_assertion description "[In order to evaluate the association of PRM1, PRM2, KIT and KITLG variants with susceptibility to severely defective spermatogenesis, 309 male infertility patients (199 cases with non-obstructive azoospermia and 110 cases with severe oligozoospermia) and 377 controls were recruited in the Chinese Han population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176533.RAfYTBU36Oan8A_ukKgOWhv-8qprO8SNcLh7blkOy_v0Y130_provenance.
- NP176536.RAWY2DXTQJESlumuxPBk9XkRvczbTn9v_l42fhnekl3F0130_assertion description "[We conclude that the constitutive expression of CD95 and Bcl-2, as well as CD95 sensitivity and P-gp function but not constitutive Bax expression depend on the maturation stage of leukemic cells in adult de novo AML.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176536.RAWY2DXTQJESlumuxPBk9XkRvczbTn9v_l42fhnekl3F0130_provenance.
- NP176547.RAalnqaApNoCTtu6CHbyQMJ-nvaNm1fgkUeXdbymBenMA130_assertion description "[Susceptibility to oral cancer by genetic polymorphisms at CYP1A1, GSTM1 and GSTT1 loci among Indians: tobacco exposure as a risk modulator.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176547.RAalnqaApNoCTtu6CHbyQMJ-nvaNm1fgkUeXdbymBenMA130_provenance.
- NP176557.RARMr6Qh6uMYOyxMjec7QsHAy6VBTzbezzLoYJpTX-n9Y130_assertion description "[Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176557.RARMr6Qh6uMYOyxMjec7QsHAy6VBTzbezzLoYJpTX-n9Y130_provenance.
- NP176558.RAbnc7Jjf08N_Uz98mdwudkRSzd6Hkn11pcukTC9JakeA130_assertion description "[Japanese patients with rheumatoid arthritis (RA) were observed to have a statistical association with HLA-DR4, MT3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176558.RAbnc7Jjf08N_Uz98mdwudkRSzd6Hkn11pcukTC9JakeA130_provenance.
- NP176568.RAY7tdlZXyVdoBFiLi8QeMY1q2aY-FlZ7xAjtfhkVh1aU130_assertion description "[Associations between adiponectin (ADIPOQ) genetic polymorphisms (rs2241766 G/T and rs266729 G/C) and cancer risk have been extensively studied in the past decade, while conflicting results were reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176568.RAY7tdlZXyVdoBFiLi8QeMY1q2aY-FlZ7xAjtfhkVh1aU130_provenance.
- NP176569.RATidFkreghytNRw7Fdmaj_QYUKl1m6KYMJ_bNICI_xkg130_assertion description "[Despite recent controversies, KRAS mutation is currently the most recognized molecular predictive marker in colorectal cancer (CRC), predicting efficacy of anti-epidermal growth factor receptor (anti-EGFR) antibodies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176569.RATidFkreghytNRw7Fdmaj_QYUKl1m6KYMJ_bNICI_xkg130_provenance.
- NP176570.RATysYckPd_VggEgKKjc9iLNFWiG3UGlXPKqbgm9s8-oo130_assertion description "[To explore how FEN1 contributes to cancer progression, we examined FEN1 expression using 241 matched pairs of cancer and corresponding normal tissues on a gene expression profiling array and validated differential expression by quantitative real-time PCR and immunohistochemistry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176570.RATysYckPd_VggEgKKjc9iLNFWiG3UGlXPKqbgm9s8-oo130_provenance.
- NP176573.RAdZESMn7JyWS3l_VbA3T6qsGA3AV6O2Suw4dGiofLpr0130_assertion description "[Our study revealed RAS genes, ACE and AGT-M235T but not AGT-T174M, AGTR1 or REN genotypes, as contributing factors for DN in type 2 diabetes mellitus in Chinese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176573.RAdZESMn7JyWS3l_VbA3T6qsGA3AV6O2Suw4dGiofLpr0130_provenance.
- NP176574.RAa4ggAdx_CIDaAUXR2YFpg3rY__5cvSVC66AX6WKAJNE130_assertion description "[Normal levels of DM RNA and myotonin protein kinase in skeletal muscle from adult myotonic dystrophy (DM) patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176574.RAa4ggAdx_CIDaAUXR2YFpg3rY__5cvSVC66AX6WKAJNE130_provenance.
- NP176575.RAUbqydkBTDROkFOq5X56EEu1uk2a_cSgGb62cDdSsLIY130_assertion description "[Sequence analysis of an immunogenic and neutralizing domain of the human T-cell lymphoma/leukemia virus type I gp46 surface membrane protein among various primate T-cell lymphoma/leukemia virus isolates including those from a patient with both HTLV-I-associated myelopathy and adult T-cell leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176575.RAUbqydkBTDROkFOq5X56EEu1uk2a_cSgGb62cDdSsLIY130_provenance.
- NP176577.RAVdEDiZmmqofCli_P4qPvApkoWkuYKMomD0Qk5yZ9pJk130_assertion description "[In a recent GWAS, we localized five IgAN susceptibility loci on Chr.6p21 (HLA-DQB1/DRB1, PSMB9/TAP1, and DPA1/DPB2 loci), Chr.1q32 (CFHR3/R1 locus), and Chr.22q12 (HORMAD2 locus).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176577.RAVdEDiZmmqofCli_P4qPvApkoWkuYKMomD0Qk5yZ9pJk130_provenance.
- NP176579.RAcTi_G76yoYjbCD9xSBmesLCT7hzQVeDzrj6_Oh_04HY130_assertion description "[We apply an empirical variance estimation method, which is implemented in the program package FBAT, on Caucasian families with asthma in the presence and absence of linkage and compare the results with those obtained using the TDT (TDTEX-PAIRS) on the same data sets.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176579.RAcTi_G76yoYjbCD9xSBmesLCT7hzQVeDzrj6_Oh_04HY130_provenance.
- NP176582.RATrnPNCxHvrpUkJQNOq-dAkTcj0MaKKgSM3imWIPrKsg130_assertion description "[The aims of this study were (i) to observe the expression of ATR, WWOX and FHIT proteins in urothelial carcinoma (UC) between endemic and non-endemic areas of blackfoot disease (BFD) by immunohistochemical analyses; (ii) to compare expression of these genes between arsenite-treated SV-HUC-1 human epithelial cells and rat uroepithelial cells; and (iii) to determine the role of DNMT and MEK inhibitors on expressions of WWOX and FHIT in response to arsenite in SV-HUC-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176582.RATrnPNCxHvrpUkJQNOq-dAkTcj0MaKKgSM3imWIPrKsg130_provenance.
- NP176587.RAc1ME2wKjF67W_2_MZBHOUbZ5us-QJIZ_bTsw8hohkCE130_assertion description "[Progranulin contributes to tumorigenesis in diverse cancers, including breast cancer, clear cell renal carcinoma, invasive ovarian carcinoma and glioblastoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176587.RAc1ME2wKjF67W_2_MZBHOUbZ5us-QJIZ_bTsw8hohkCE130_provenance.
- NP176588.RAbf4QMDMHA0YkXENi40Dbh9GBopEJkBWzGAbpd-t-j0M130_assertion description "[Using a combination of cDNA subtraction and microarray analysis, we report here the identification and characterization of L552S, an over-expressed, alternatively spliced isoform of XAGE-1 in lung adenocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176588.RAbf4QMDMHA0YkXENi40Dbh9GBopEJkBWzGAbpd-t-j0M130_provenance.
- NP176599.RAVA1tCW40Twnst73k7VvffUd8xhr_EI44OBKOz6mLXeo130_assertion description "[Radiosensitivity in breast cancer assessed by the histone γ-H2AX and 53BP1 foci.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176599.RAVA1tCW40Twnst73k7VvffUd8xhr_EI44OBKOz6mLXeo130_provenance.
- NP176600.RAVTE7zHeZtEkq1yOsV-udS4Zq5hn_g8CNT1wsIIsdlaI130_assertion description "[Gene fusions involving members of the RAF family of protein kinases have recently been identified as characteristic aberrations of low-grade astrocytomas, the most common tumors of the central nervous system in children.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176600.RAVTE7zHeZtEkq1yOsV-udS4Zq5hn_g8CNT1wsIIsdlaI130_provenance.
- NP176602.RAX8A0BGEU6Bcp5ZdljCcVVZd_jKeScpaohC9XXjGebC0130_assertion description "[Although the precise mechanism remains incompletely understood, Ag presentation and subsequent myelin-reactive CD4(+) T cell activation/differentiation are essential for the pathogenesis of MS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176602.RAX8A0BGEU6Bcp5ZdljCcVVZd_jKeScpaohC9XXjGebC0130_provenance.
- NP176607.RAdW2iT3nugXX7ZT8P0TFUtkDq_RMEvZgFQELpRupV_5Q130_assertion description "[Interestingly, miR-33a/b also act in the fatty acid/lipid homeostasis pathway by controlling the fatty acid β-oxidation genes carnitine O-octanoyltransferase (CROT), hydroxyacyl-coenzyme A-dehydrogenase (HADHB), and carnitine palmitoyltransferase 1A (CPT1A), as well as the energy sensor AMP-activated protein kinase (AMPKα1), the NAD(+)-dependent sirtuin SIRT6, and the insulin signaling intermediate IRS2, key regulators of glucose and lipid metabolism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176607.RAdW2iT3nugXX7ZT8P0TFUtkDq_RMEvZgFQELpRupV_5Q130_provenance.
- NP176608.RAfLMFa2NM1tMTjPF48kq7LeqpqAqG5n3Humy7WaFiay4130_assertion description "[Moreover, CDDO-Me (7.5 mg/kg/day) also inhibited pancreatic human L3.6pL tumor growth and down-regulated Sp1, Sp3, and Sp4 in tumors using an orthotopic pancreatic cancer model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176608.RAfLMFa2NM1tMTjPF48kq7LeqpqAqG5n3Humy7WaFiay4130_provenance.
- NP176610.RAUn8zMDS9Yop-GkQXTHzCZdGaH1lo92YsomnE-IwySmc130_assertion description "[Among the 15 sporadic SCA patients, genetic mutations for SCA2, SCA6, SCA17, and SCA31 were identified, indicating that ADCAs should be considered in sporadic cases of ataxia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176610.RAUn8zMDS9Yop-GkQXTHzCZdGaH1lo92YsomnE-IwySmc130_provenance.
- NP176611.RAZ67MjFMkrXOo1gctl9TJ12sfDi-V84f5b36QOy6Kpsk130_assertion description "[The interaction between miR-200c and BRD7 might have important roles in controlling growth of endometrial of cancer cells and suggest a novel target pathway for treatment of this cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176611.RAZ67MjFMkrXOo1gctl9TJ12sfDi-V84f5b36QOy6Kpsk130_provenance.
- NP176612.RAUpSHGy-j-okPIiuNgBl02g-wcvsmiz3d3tmF8t4zeNE130_assertion description "[The cytokines interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha), and IL-6 induce osteoclast formation and may contribute to the development of postmenopausal osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176612.RAUpSHGy-j-okPIiuNgBl02g-wcvsmiz3d3tmF8t4zeNE130_provenance.
- NP176615.RAWzrrZmSm9NtEPanZ8FtqU5-2_aM1rhN35x0G3qUfCBc130_assertion description "[Shorter CAG repeats of the AR gene, presenting high levels of transactivation activity, may play a role in male AS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176615.RAWzrrZmSm9NtEPanZ8FtqU5-2_aM1rhN35x0G3qUfCBc130_provenance.
- NP176616.RAQJSbfRQFau4iu4eTQugwlUCyejzZhluUdVe6YZO7Lg0130_assertion description "[Forty-six of these individuals (59%) had no atherosclerosis, 32 patients (41%) had atherosclerosis, i.e., atherosclerosis of the extracranial carotid arteries (CAA), coronary arteries (CAD) or/and peripheral arteries of the legs (PVD), either singly or in combination.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176616.RAQJSbfRQFau4iu4eTQugwlUCyejzZhluUdVe6YZO7Lg0130_provenance.
- NP176619.RAVekfi7rRqQTZdxoCKYNferoS9Aju5BzvGEmhZYLD89A130_assertion description "[These results suggested that CT genes, especially NY-ESO-1 and LAGE-1, do express in CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176619.RAVekfi7rRqQTZdxoCKYNferoS9Aju5BzvGEmhZYLD89A130_provenance.
- NP176629.RASt0bP8Kd7bZrZwJ9OUeCGisum5wgnhsL9E5lWz5XmXo130_assertion description "[Detection of porcine parvovirus using a taqman-based real-time pcr with primers and probe designed for the NS1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176629.RASt0bP8Kd7bZrZwJ9OUeCGisum5wgnhsL9E5lWz5XmXo130_provenance.
- NP176635.RAf7_uxlYTWgXizJ0oc6V3Cmc20QZ_QgqYbNZzkWP1u0s130_assertion description "[Initially, mutations in the BCL10 gene were reported to occur at a high frequency in various types of lymphomas and solid tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176635.RAf7_uxlYTWgXizJ0oc6V3Cmc20QZ_QgqYbNZzkWP1u0s130_provenance.
- NP176636.RAV-rsAVxKbfTJAiLVfipjX-I_IgRQbCVP3trLnWsZmBM130_assertion description "[To investigate the role of microRNA (miRNA) in regulating epithelial-to-mesenchymal transition (EMT) during human posterior capsule opacification (PCO).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176636.RAV-rsAVxKbfTJAiLVfipjX-I_IgRQbCVP3trLnWsZmBM130_provenance.
- NP176638.RAZn59o2lMTzO6byrsryeBJdjm8KgT-2iCA_R_IpjaQcg130_assertion description "[Irreversible EGFR inhibitor EKB-569 targets low-LET γ-radiation-triggered rel orchestration and potentiates cell death in squamous cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176638.RAZn59o2lMTzO6byrsryeBJdjm8KgT-2iCA_R_IpjaQcg130_provenance.
- NP176640.RAWKurzhRg2gfUBkJHUpWFHA3Pkzj0bSKWfzoupEXk3ys130_assertion description "[Polymorphism in the promoter of the IL-4 gene is associated with asthma and is a disease modifier in terms of the severity of AHR.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176640.RAWKurzhRg2gfUBkJHUpWFHA3Pkzj0bSKWfzoupEXk3ys130_provenance.
- NP176645.RAVOjymud1eG67TkMSufmcDe1wRfLodqpfmcY8CnmWzbw130_assertion description "[A new AHI-1-BCR-ABL-JAK2 interaction complex has recently been identified and this complex regulates transforming activities and drug resistance in CML stem/progenitor cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176645.RAVOjymud1eG67TkMSufmcDe1wRfLodqpfmcY8CnmWzbw130_provenance.
- NP176647.RATHnj6uAkVta5txsyddJ1T1rrdbsYfqvIAhlzXwYqJS8130_assertion description "[Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176647.RATHnj6uAkVta5txsyddJ1T1rrdbsYfqvIAhlzXwYqJS8130_provenance.
- NP176651.RAaSxSOGl1Pwp9pkRIyx6tsawDOQfLZd0D0ggZvQoVbMw130_assertion description "[A micro-array analysis using biopsies from patients with EBV-positive undifferentiated nasopharyngeal carcinoma (NPC) and from cancer-free controls revealed down-regulation of tumour suppressor genes (TSG) not previously associated with this disease; one such gene was the ataxia telangiectasia mutated (ATM) gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176651.RAaSxSOGl1Pwp9pkRIyx6tsawDOQfLZd0D0ggZvQoVbMw130_provenance.
- NP176652.RAfKpw4l_z-ebA74TcoHiaKZscMErEDmaizBpb20rxbbg130_assertion description "[The aim of the present study was to determine how DNA methylation affected the expression of the THRB gene in differentiated thyroid cancer (DTC) and how reexpression of the THRB gene attenuated the cancer phenotypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176652.RAfKpw4l_z-ebA74TcoHiaKZscMErEDmaizBpb20rxbbg130_provenance.
- NP176656.RAVEqb0D0_HFLn6qZkP3pebiZKE2c81ma75vkiZy9YbEw130_assertion description "[Stromal podoplanin expression in 14 common cancer types was significantly associated with tumor stage (P < .001), lymph node metastases (P < .001), lymphatic invasion (P = .02), and venous invasion (P < .001).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176656.RAVEqb0D0_HFLn6qZkP3pebiZKE2c81ma75vkiZy9YbEw130_provenance.
- NP176657.RAUZp-5-xDWunXSSXRjHG-aOMCXDY-EvDn0ChNhCtNaq4130_assertion description "[RT-qPCR confirmed the microarray findings and was used to investigate MT3 mRNA gene expression in tumor samples of a series of 52 different pituitary adenoma subtypes comprising 10 corticotropin (ACTH)-producing, 18 growth hormone (GH)-producing, 8 prolactin (PRL)-producing, and 16 nonfunctional adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176657.RAUZp-5-xDWunXSSXRjHG-aOMCXDY-EvDn0ChNhCtNaq4130_provenance.
- NP176660.RAfszcIAggvsr4BU9Xbp4B_EbF1tMfyqq94-Fw0G1syh8130_assertion description "[Iron-refractory iron deficiency anaemia (IRIDA) is a rare disorder which was linked to mutations in two genes (SLC11A2 and TMPRSS6).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176660.RAfszcIAggvsr4BU9Xbp4B_EbF1tMfyqq94-Fw0G1syh8130_provenance.
- NP176661.RAecybD0Rfpl0oTDSuhbx71Xbu8g5eCF4A3SI-57h7PyI130_assertion description "[The presence of Chlamydia-like organism DNA was investigated by polymerase chain reaction (PCR) in cerebrospinal fluid (CSF) samples from 27 patients previously found positive for Chlamydia pneumoniae DNA: 12 with multiple sclerosis (MS), grouped according to clinical and magnetic resonance imaging (MRI) evidence of disease activity, 8 with other inflammatory neurological disorders and 7 with non-inflammatory neurological disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176661.RAecybD0Rfpl0oTDSuhbx71Xbu8g5eCF4A3SI-57h7PyI130_provenance.
- NP176662.RATuDe346ecUsCwxvMSzEp8skaL7o8Kt_kmUZU22sH_f4130_assertion description "[Fusion tyrosine kinases (FTKs) such as BCR/ABL, TEL/ABL, TEL/JAK2, TEL/PDGF beta R, TEL/TRKC(L), and NPM/ALK arise from reciprocal chromosomal translocations and cause acute and chronic leukemias and non-Hodgkin's lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176662.RATuDe346ecUsCwxvMSzEp8skaL7o8Kt_kmUZU22sH_f4130_provenance.
- NP176669.RAVgWyWyXViUE0qFsJCYwor34whCyU37BMNpsRQfJIOAs130_assertion description "[To date, CAPN10 has been found to be extensively associated with hyperinsulinaemia and type 2 diabetes mellitus, by different groups.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176669.RAVgWyWyXViUE0qFsJCYwor34whCyU37BMNpsRQfJIOAs130_provenance.
- NP176670.RAbMEiYspvxm7TA9s2NyMf98_g-LBjaNd-3CIbHiIZQeE130_assertion description "[We demonstrate applications in large-scale disease studies, by identifying PTDs in MLL, ITDs in FLT3, and reciprocal fusions between PML and RARA, in two deeply sequenced acute myeloid leukemia (AML) RNA-seq datasets.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176670.RAbMEiYspvxm7TA9s2NyMf98_g-LBjaNd-3CIbHiIZQeE130_provenance.
- NP176677.RAWJx3NV6fBoWKz1UVuLK_uHx7RYMEyV-ATv-d5UOsazE130_assertion description "[c-Jun/AP-1 has been linked to invasive properties of aggressive breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176677.RAWJx3NV6fBoWKz1UVuLK_uHx7RYMEyV-ATv-d5UOsazE130_provenance.
- NP176678.RAfBH84_KLGqaPMMCTTwUXsp0pLYM3nYWYYm4WYbBksyY130_assertion description "[To determine whether genetic variation in AKT2 plays a broader role in human metabolic disease, we sequenced the entire coding region and splice junctions of AKT2 in 94 unrelated patients with severe insulin resistance, 35 of whom had partial lipodystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176678.RAfBH84_KLGqaPMMCTTwUXsp0pLYM3nYWYYm4WYbBksyY130_provenance.
- NP176680.RAWbNudxFBg9DMGEKd6in5WSMx5wWfHtnsCuoUXWiohK8130_assertion description "[A number of polymorphisms in various genes have been identified and associated with bone mineral density (BMD) and with an increased risk of osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176680.RAWbNudxFBg9DMGEKd6in5WSMx5wWfHtnsCuoUXWiohK8130_provenance.
- NP176681.RARdRBvI2LhnHH4OfDRSDbRmwCG_E-QDLv83mlApI0dT8130_assertion description "[Serum biochemistry and radiological investigations for primary hyperparathyroidism, MEN1 and HPT-JT, and genetic testing for MEN1 and HRPT2 mutations were undertaken.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176681.RARdRBvI2LhnHH4OfDRSDbRmwCG_E-QDLv83mlApI0dT8130_provenance.
- NP176683.RAROCH0Bbu3g0QZ8SZ8Th29bAG5WQnW3S-nwq-bweOu2A130_assertion description "[To perform SCA8 repeat expansion analysis in a heterogeneous group of ataxic patients, to determine the prevalence of this mutation in our patients and establish the frequency of expanded CTA/CTG repeats in a large group of control subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176683.RAROCH0Bbu3g0QZ8SZ8Th29bAG5WQnW3S-nwq-bweOu2A130_provenance.
- NP176684.RAeUsLilQ2heR7OEOQkZcgSfPYDAT3Jy37yx9GCA_K48M130_assertion description "[INTRODUCTION AND DISCUSSION: Molecular genetic investigations relating to thyroid cancer have started to gain clinical importance, with discovery of the tumor-specific oncogenes PTC 1-3 in papillary thyroid cancer and the syndrome-specific mutations of the RET protooncogene in MEN-2a, MEN-2b and familial MTC patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176684.RAeUsLilQ2heR7OEOQkZcgSfPYDAT3Jy37yx9GCA_K48M130_provenance.
- NP176688.RARVVRBRy-jJcSJoMB51p2NTUd_Vky6YClhFUkDWN1SHU130_assertion description "[Recent studies identified multimerin as a specific coagulation factor V binding protein, complexed with platelet, but not plasma, factor V. These findings led us to investigate individuals with inherited factor V deficiencies for possible multimerin abnormalities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176688.RARVVRBRy-jJcSJoMB51p2NTUd_Vky6YClhFUkDWN1SHU130_provenance.
- NP176689.RAbnd_DmArmrWhl556zYezo7MDhF6Ez3SOG9qd3BJ-HxA130_assertion description "[Here, we explore the relationship between three common IGF polymorphisms [C/T single-nucleotide polymorphism (SNP) (rs7965399) and a dinucleotide repeat (CA)n within the 5' regulatory region of the IGF-1 gene and the -202 A/C SNP in the IGFBP-3 gene], serum levels and prostate cancer (Pca) risk in 767 African-Americans enrolled in a clinic-based case-control study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176689.RAbnd_DmArmrWhl556zYezo7MDhF6Ez3SOG9qd3BJ-HxA130_provenance.