Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP176691.RASH1GJEfYSUmUoK0GYUhvdlshxmVd0JFuBsi7XcBxyvU130_assertion description "[Galectin-1 is a novel functional receptor for tissue plasminogen activator in pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176691.RASH1GJEfYSUmUoK0GYUhvdlshxmVd0JFuBsi7XcBxyvU130_provenance.
- NP176693.RAaCDbJt3G8vutWUF-lefHeGq2SH3OHeeI0o0Ku2tNmNI130_assertion description "[However, to our knowledge, there are no reports that describe the association between chromosomal abnormalities in MDS and graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (allo-SCT).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176693.RAaCDbJt3G8vutWUF-lefHeGq2SH3OHeeI0o0Ku2tNmNI130_provenance.
- NP176697.RAf6hVl8xO6bFQaK763JOicVVcR3UyPLlkqE9i5ZAgdHw130_assertion description "[The achondroplasia class of chondrodysplasias comprises the most common genetic forms of dwarfism in humans and includes achondroplasia, hypochondroplasia and thanatophoric dysplasia types I and II (TDI and TDII), which are caused by different mutations in a fibroblast growth-factor receptor FGFR3 (ref.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176697.RAf6hVl8xO6bFQaK763JOicVVcR3UyPLlkqE9i5ZAgdHw130_provenance.
- NP176698.RARVetG5CHf2sRuz9rBKdox__gM01ez2nJEcuB2g1_RFA130_assertion description "[However, significant interaction was found between APOE-epsilon4 genotype and SMC on depression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176698.RARVetG5CHf2sRuz9rBKdox__gM01ez2nJEcuB2g1_RFA130_provenance.
- NP176699.RATRPFq1sewXvht6XbRkjMSaPwUVBu8ghIyfhwVMSql_U130_assertion description "[Genes in the BRCA1 preneoplastic signature included several known tumor suppressor genes such as CDKN1C and EFEMP1 and several thought to be important in invasion and metastasis such as E2F3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176699.RATRPFq1sewXvht6XbRkjMSaPwUVBu8ghIyfhwVMSql_U130_provenance.
- NP176704.RATydxAjuKQhdiqiQWthow9vKdav1_FLMNGyUiQDSGF2U130_assertion description "[cavity lesions) were analyzed for p53 and Ki-67 expression by immunohistochemistry, loss of heterozygosity by PCR amplification, p53 mutations by PCR-based direct sequencing, and CP by in situ hybridization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176704.RATydxAjuKQhdiqiQWthow9vKdav1_FLMNGyUiQDSGF2U130_provenance.
- NP176710.RAc_nFnuV1mIW63hvdrpGAQA-jiVLHBL6OXXMw9CO7g6Q130_assertion description "[In this study, we examined the clinical and cystic fibrosis transmembrane-conductance regulator (CFTR) gene mutations in sixty patients with bilateral absence of vas deferens that applied to andrology clinic due to male factor infertility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176710.RAc_nFnuV1mIW63hvdrpGAQA-jiVLHBL6OXXMw9CO7g6Q130_provenance.
- NP176715.RAaDXzizGufLILjEgw7uJQwuf0M4cZSqLhw-w0lETHxZM130_assertion description "[Evidence for a cancer-specific switch at the CDK4 promoter with loss of control by both USF and c-Myc.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176715.RAaDXzizGufLILjEgw7uJQwuf0M4cZSqLhw-w0lETHxZM130_provenance.
- NP176717.RAWMH9yhN5OkpXGG4FjNsZ_FGV3InuhcOTdEvHynLcvfA130_assertion description "[Analysis of IRS1 immunostaining in 24 cases of primary CRC with paired colonic epithelium and hepatic metastasis showed that staining intensity was significantly higher in metastases relative to both primary CRC (P<0.01) and colonic epithelium (P<0.01).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176717.RAWMH9yhN5OkpXGG4FjNsZ_FGV3InuhcOTdEvHynLcvfA130_provenance.
- NP176718.RAcOjtSnCWcxLmYRl2ODrpSEGrOuXYj_5NSaE8acxxmN4130_assertion description "[Genetic screening of RET proto-oncogene is a powerful tool for the early identification of familial cases of medullary thyroid carcinoma (MTC), comprising isolated familial thyroid medullary carcinoma (FMTC) and multiple endocrine neoplasia syndromes 2A (MEN-2A) and 2B (MEN-2B).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176718.RAcOjtSnCWcxLmYRl2ODrpSEGrOuXYj_5NSaE8acxxmN4130_provenance.
- NP176720.RAQCEgL0-GtPKvIZFLwUteDTsIw2xKn6LDLEZhkvuYXUM130_assertion description "[FVL mutation in heterozygous form is common among VTE patients and significantly increases the risk for VTE recurrence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176720.RAQCEgL0-GtPKvIZFLwUteDTsIw2xKn6LDLEZhkvuYXUM130_provenance.
- NP176722.RARUcayNAETv1BkVAMEgnjpCFWyqoKQa2IeJdtI2bAsQI130_assertion description "[Supernatant from amphotropic retrovirus-producing cells harboring the BAG vectors was incubated with sera or cerebrospinal fluid (CSF) of patients with gliomas or unrelated disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176722.RARUcayNAETv1BkVAMEgnjpCFWyqoKQa2IeJdtI2bAsQI130_provenance.
- NP176732.RAbVO68dYu20jrQE7mCStDiFxqYyHMQs_B0JCzp4C_9lc130_assertion description "[The incidence of colon cancer with MMR defect was 10/171 (6%).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176732.RAbVO68dYu20jrQE7mCStDiFxqYyHMQs_B0JCzp4C_9lc130_provenance.
- NP176748.RAeHfElD6PKMsFBJZzyWly-Wb_owCjBKPQmbS4jroZObA130_assertion description "[The concordance of skin prick test (SPT), radioallergosorbent test (RAST) and IgE-binding profiles of sera were examined from a large cohort of monozygotic and dizygotic twins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176748.RAeHfElD6PKMsFBJZzyWly-Wb_owCjBKPQmbS4jroZObA130_provenance.
- NP176756.RAZLljXI9K_r0HgtGIPxG0Pft3q9laMoMLd-gxUqNHVJ4130_assertion description "[FISH was performed using four locus-specific identifier probes [Ras responsive element binding protein (RREB)1, myeloblastosis viral oncogene homologue (MYB), cyclin (CCN)D1 and centromere of chromosome (CEP)6], and results were compared with the clinical long-term follow-up and histopathological diagnosis data.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176756.RAZLljXI9K_r0HgtGIPxG0Pft3q9laMoMLd-gxUqNHVJ4130_provenance.
- NP176758.RAQc8iDVV6t__7D6HxT7_BtDsAQGBFXv0-zTgcaivCGgQ130_assertion description "[Based on the present results, the G-T-T haplotype appears to be a genetic marker of EH, and the APE1/REF-1 gene appears to be a susceptibility gene for EH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176758.RAQc8iDVV6t__7D6HxT7_BtDsAQGBFXv0-zTgcaivCGgQ130_provenance.
- NP176769.RAQ188hvV0eSnxOqSDAHyBb5754NDSr6aDrtUXRPErsZY130_assertion description "[Eighteen patients with sporadic DURS without cytogenetic abnormalities involving the DURS1 region were screened for point mutations in the candidate DURS1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176769.RAQ188hvV0eSnxOqSDAHyBb5754NDSr6aDrtUXRPErsZY130_provenance.
- NP176773.RAW1Wwl_RfBzmOiTzPRMbrCW0O0qBHsdg5j4Xyzf1DlTQ130_assertion description "[Both genes are known to be targeted also by other neoplasia-specific translocations, PBX1 in acute lymphoblastic leukemia and EWSR1 in several solid tumors, most of which are malignant.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176773.RAW1Wwl_RfBzmOiTzPRMbrCW0O0qBHsdg5j4Xyzf1DlTQ130_provenance.
- NP176776.RAfVDK0wHjHX_DjWVC9kBDD9cKqsTlTXiZC4lNmswFzog130_assertion description "[We therefore assessed the relationship between AR repeat variation and breast cancer in young women from the general population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176776.RAfVDK0wHjHX_DjWVC9kBDD9cKqsTlTXiZC4lNmswFzog130_provenance.
- NP176777.RAZ7YSZ8ybg_MLIkCH8wDp_C2DG8Y-otwz_w3T6dmmkMc130_assertion description "[However, we recently established that ectopic expression of TGF-β1 abrogates collagen accumulation via canonical SMAD signaling mechanisms in a shear-induced model of kidney fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176777.RAZ7YSZ8ybg_MLIkCH8wDp_C2DG8Y-otwz_w3T6dmmkMc130_provenance.
- NP176778.RAaNKuTA3iclm5Lp4bcB9MzaatczkimpKDj22SK6Iu3DQ130_assertion description "[Cyclin-dependent kinase inhibitor 2A (CDKN2A/p16), mesoderm-specific transcript, forkhead box M1, v-myb myeloblastosis viral oncogene homolog (avian)-like2 (v-Myb), minichromosome maintenance proteins 2, 4, and 5, cyclin B1, prostaglandin E synthase (PTGES), topoisomerase II alpha (TOP2A), ubiquitin-conjugating enzyme E2C, CD97 antigen, E2F transcription factor 1, and dUTP pyrophosphatase were among the most highly overexpressed genes in CVX when compared to NCK.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176778.RAaNKuTA3iclm5Lp4bcB9MzaatczkimpKDj22SK6Iu3DQ130_provenance.
- NP176779.RAavCNfvZepyB7nkD-6LE53iOu7ypziKhT7fZ0b36QC0Q130_assertion description "[Germline gain-of-function mutations in SOS1 cause Noonan syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176779.RAavCNfvZepyB7nkD-6LE53iOu7ypziKhT7fZ0b36QC0Q130_provenance.
- NP176781.RAdcWfx_0xvdZHEW0X9TLH9HP-HqlI4QL6LN4QO22Xdxo130_assertion description "[Overall this study unravels a recurrent pattern of secondary genetic alterations in IRF4 translocation-positive lymphomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176781.RAdcWfx_0xvdZHEW0X9TLH9HP-HqlI4QL6LN4QO22Xdxo130_provenance.
- NP176790.RASMy1n4glUo6gJ9NtaA4rVSUQKLAA-RbVCIRtxLLyur4130_assertion description "[The expression of EGFR, HER-2/neu-encoded receptor protein, and mutant p53 product was significantly lower in LMP tumors than in carcinomas (p < 0.05).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176790.RASMy1n4glUo6gJ9NtaA4rVSUQKLAA-RbVCIRtxLLyur4130_provenance.
- NP176794.RAbQQycud3MCAiij0-SxovVQIB1bIBlsAzMiR3vqRRWLY130_assertion description "[These findings suggest that MSI+ GCs with and without MLH1 methylation may have different clinicopathologic features.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176794.RAbQQycud3MCAiij0-SxovVQIB1bIBlsAzMiR3vqRRWLY130_provenance.
- NP176802.RAZX79tFmP16nWXchlNQWJwDJ0gskZR3PdPTMW9CsmwDo130_assertion description "[Endothelial nitric oxide synthase gene polymorphisms (894G > T and -786T > C) and risk of coronary artery disease in a Saudi population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176802.RAZX79tFmP16nWXchlNQWJwDJ0gskZR3PdPTMW9CsmwDo130_provenance.
- NP176803.RAZbJWhTDYmKKekGRTVN08wQmCLRdlUh0pkT6MN8IPbc4130_assertion description "[In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has received enthusiastic investigation, and significant progress has been made toward understanding its tumorigenic role and clinical significance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176803.RAZbJWhTDYmKKekGRTVN08wQmCLRdlUh0pkT6MN8IPbc4130_provenance.
- NP176804.RAcDIXfs7divnxnoLIbeYkGpMLER05LysRcffKH1QtRE4130_assertion description "[ACC-HGT may not necessarily reflect a more advanced stage of tumor progression, but rather a transformation to another histological form in which the poorly differentiated forms (PDC) presents a genetic complexity similar to the solid ACC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176804.RAcDIXfs7divnxnoLIbeYkGpMLER05LysRcffKH1QtRE4130_provenance.
- NP176809.RAeqDIgvTbLv73eVZEWilyZxg59tWXskc3oFYs706sCLs130_assertion description "[Type I mutants (three complementation groups) are completely defective in induction of the invariant-chain and class II HLA-DP, -DQ, -DR, and -DM genes, whereas type II mutants (two complementation groups) induce these genes weakly in response to IFN-gamma, in the order DPB > DRA > invariant chain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176809.RAeqDIgvTbLv73eVZEWilyZxg59tWXskc3oFYs706sCLs130_provenance.
- NP176811.RAXw8xSGA3p0lk53Isd3hQw6x0kgtq1zMTh-FC3bREnes130_assertion description "[Patients were evaluated with a neuropsychometric battery for CD 1 day and 1 month after CEA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176811.RAXw8xSGA3p0lk53Isd3hQw6x0kgtq1zMTh-FC3bREnes130_provenance.
- NP176829.RAVhBwqTz90XQHvSNQ2ZrogKaRocFUtFH1sZq50xOCwfk130_assertion description "[Another feature of AD is abnormal phospholipid turnover, which might be related to the progressive accumulation of apolipoprotein E (apoE) within amyloid plaques, leading perhaps to the reduction of apoE content in the CSF of AD patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176829.RAVhBwqTz90XQHvSNQ2ZrogKaRocFUtFH1sZq50xOCwfk130_provenance.
- NP176830.RAeuc6nt7nYPr4fUTEBEzuqmvel-KdfO3ERJqUa7uAzGw130_assertion description "[In the case of the IL-4 promoter gene, the frequency of the CC homozygote was significantly lower in the MCNS group than in the controls, while, in the case of IL-13, the frequency of the GG homozygote was significantly lower in the MCNS group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176830.RAeuc6nt7nYPr4fUTEBEzuqmvel-KdfO3ERJqUa7uAzGw130_provenance.
- NP176831.RAWD012sKVIt-K1QRa8HK1QdEL_4JPAxTeVeglM33CjbE130_assertion description "[This suggests that glycine-extended gastrin and its novel receptors may play a role in colon cancer cell growth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176831.RAWD012sKVIt-K1QRa8HK1QdEL_4JPAxTeVeglM33CjbE130_provenance.
- NP176848.RAU_nV4EdglCMnzKdmrzgP7vta-EZMdaizye-jcGSR8mM130_assertion description "[The Philadelphia chromosome consists of a reciprocal translocation between the ABL oncogene at chromosome 9q34 and the BCR gene at chromosome 22q11, resulting in the expression of chimeric BCR-ABL mRNAs specific to chronic myelogenous leukemia (CML).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176848.RAU_nV4EdglCMnzKdmrzgP7vta-EZMdaizye-jcGSR8mM130_provenance.
- NP176852.RAbFyr-Fa3eCChm6Q_CkNXd_yPeZ0n5ko6IJUxwJrCm-8130_assertion description "[These data underline the value of MDR 1 gene expression as a powerful prognostic factor in AML for response to the first induction treatment and overall survival, sustaining the use of MDR 1 modulators for first-line therapy in this disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176852.RAbFyr-Fa3eCChm6Q_CkNXd_yPeZ0n5ko6IJUxwJrCm-8130_provenance.
- NP176853.RAS4ewr3xqAsiX1u3Y48J6jzkLpRmKrn8cY4AxUUMh9io130_assertion description "[Our data indicate that CD44 standard transcripts, including the epithelial form (C-v8,v9,v10-C) corresponding to a 720 bp transcript, were detected in 2/38 (5.2%) samples of normal mucosa, 20/20 (100%) adenomas and in 21/33 (63%) colorectal carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176853.RAS4ewr3xqAsiX1u3Y48J6jzkLpRmKrn8cY4AxUUMh9io130_provenance.
- NP176857.RAVrdkI9FdAV0KRFCTaDQvYBH4NAJVXrIsq50c1ioGBZo130_assertion description "[LEMD3 haploinsufficiency and point mutations have been previously associated with osteopoikilosis but radiographs of our patient at the age of 16 years did not reveal any hint for osteopoikilosis lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176857.RAVrdkI9FdAV0KRFCTaDQvYBH4NAJVXrIsq50c1ioGBZo130_provenance.
- NP176858.RARipPaWK6GYHRoYrYg_RegCyFnQ17JFcSaGL1HxDKdMg130_assertion description "[We did not observe significant differences in the prevalence of CAT -262 C/T polymorphic variants in SLE patients and controls, however, we found that patients with the CAT -262 CT and TT genotypes had low CAT activity, and these genotypes showed a significant association with thrombocytopaenia, leukopaenia and the presence of anti-snRNP in SLE patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176858.RARipPaWK6GYHRoYrYg_RegCyFnQ17JFcSaGL1HxDKdMg130_provenance.
- NP176859.RAd27HeEJiQOszut68Q8086Z4Y5e1aAV7bWpSROV0iK04130_assertion description "[These results combined indicate that PSA facilitates tumor invasion of glioma in the brain, and that NCAM-NCAM interaction is likely attenuated in the PSA-mediated tumor invasion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176859.RAd27HeEJiQOszut68Q8086Z4Y5e1aAV7bWpSROV0iK04130_provenance.
- NP176861.RAei1z4uitmC663HjSdO8u6nvPbgW83eK56OwD_Qat2qk130_assertion description "[Thus, we propose that the association of ATG16L1*300A with increased risk of Crohn's disease is due to impaired bacterial handling and lowered rates of bacterial capture by autophagy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176861.RAei1z4uitmC663HjSdO8u6nvPbgW83eK56OwD_Qat2qk130_provenance.
- NP176867.RAUFKJlUD08yr24cjPHVV8onylE7doOZESz9kk3MGIOVw130_assertion description "[ACE I/D (rs4340), ACE A11860G (rs4343), AT1R A1166C (rs5186), AGT T174M (rs4762) and AGT M235T (rs699) gene polymorphisms were PCR-RFLP analysed in 298 CAD patients and 510 controls from Portugal.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176867.RAUFKJlUD08yr24cjPHVV8onylE7doOZESz9kk3MGIOVw130_provenance.
- NP176868.RAZPx1_ohz94O8t-pZNbL8hjbuz1miALC6hE2s0o6W31c130_assertion description "[This was documented in FH patients identified on the island of Sardinia, in Italy, where 12% of the inhabitants are carriers of beta-thalassemia due to a single mutation (Q39X) of the beta-globin gene that abolishes the synthesis of beta-globin chain of hemoglobin (beta(o)-thalassemia).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176868.RAZPx1_ohz94O8t-pZNbL8hjbuz1miALC6hE2s0o6W31c130_provenance.
- NP176877.RASzJZh0Q4gYpCV3zTxOMj9j7EuZYbntf7ybAc8AQUx_g130_assertion description "[Since HLA proteins influence T-cell recognition, phenotypes of 21 CMV-R patients were examined to determine whether certain HLA alleles were associated with low immune response and predisposed AIDS patients to CMV-R. HLA DR7 and B44 were at increased (nearly twice the expected) frequency in those with CMV-R.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176877.RASzJZh0Q4gYpCV3zTxOMj9j7EuZYbntf7ybAc8AQUx_g130_provenance.
- NP176881.RAavVNmdmiy8XqWfxLTfohnwSpSta7SQOCVq77K5kiHWI130_assertion description "[Vascular endothelin converting enzyme-1 expression and activity is upregulated in clinical diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176881.RAavVNmdmiy8XqWfxLTfohnwSpSta7SQOCVq77K5kiHWI130_provenance.
- NP176882.RAW2h3zbhFMPHSeQZmijhCx2KlXIhglYyl78-FclHQ9zE130_assertion description "[Chromosomal aberrations were syntenic to those in human neuroblastoma, including 17q gain and MYCN oncogene amplification.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176882.RAW2h3zbhFMPHSeQZmijhCx2KlXIhglYyl78-FclHQ9zE130_provenance.
- NP176886.RATP2Ne_O9R8bU0Y5P-g1QHtwVpG4miA8HlPADcPbHrKQ130_assertion description "[Mutations in the p53 gene have been detected both in papillomas and carcinomas, suggesting that p53 dysfunction plays a part in these neoplasias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176886.RATP2Ne_O9R8bU0Y5P-g1QHtwVpG4miA8HlPADcPbHrKQ130_provenance.
- NP176891.RAfQdH4KfAOUL2oMxjmmYsRne9N6vFiHNY8ULMG_Mt62E130_assertion description "[The role of matrix metalloproteinase-2 promoter polymorphisms in coronary artery disease and myocardial infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176891.RAfQdH4KfAOUL2oMxjmmYsRne9N6vFiHNY8ULMG_Mt62E130_provenance.
- NP176892.RAWNV6i-wfZ59kayqLSplb1Kb1ejTNzgTTqyI6w8-t15w130_assertion description "[Accepted causes of familial thrombophilia include the factor V Leiden defect and the prothrombin 20210 G > A variant, as well as deficiencies of antithrombin, protein C and protein S. Together these inherited abnormalities account for 30-50% of individuals presenting with venous thromboembolism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176892.RAWNV6i-wfZ59kayqLSplb1Kb1ejTNzgTTqyI6w8-t15w130_provenance.
- NP176898.RAYkevLaWedpvvcOvfqO5r5UQj8_udzaPmIbV24cufIYs130_assertion description "[Expression levels of amyloid beta (Abeta)-degrading enzymes, insulin degrading enzyme (IDE) and neprilysin (NEP), were examined in transgenic mice with Alzheimer's disease-like neuropathology.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176898.RAYkevLaWedpvvcOvfqO5r5UQj8_udzaPmIbV24cufIYs130_provenance.
- NP176900.RAfJJhxIs3OrL_mDbW8_kkanKN-mQGmBwfayU2G7mxSDQ130_assertion description "[Here we tested the hypothesis that cell-based delivery of a controlled VEGF level could induce normal angiogenesis in the heart, while preventing the development of angiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176900.RAfJJhxIs3OrL_mDbW8_kkanKN-mQGmBwfayU2G7mxSDQ130_provenance.
- NP176901.RAYtsTNnsuSiNp3v7_oSCIvkxDRmmWwMaBQTPszBo2aUI130_assertion description "[Since previous research showed that SIRT1 and K-Ras/Akt signaling acted as a promoter in tumorigenesis of pancreatic cancer, our present research set out to explore whether NAM inhibits proliferation and facilitates chemosensitivity in pancreatic cancer cells as well as the potential mechanisms involving SIRT1 and K-Ras/Akt pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176901.RAYtsTNnsuSiNp3v7_oSCIvkxDRmmWwMaBQTPszBo2aUI130_provenance.
- NP176904.RAWBXmdc7sVi2mO4KU9-iPg9CWDsu5eB0LiLxDUra7GSo130_assertion description "[Immunohistochemical analysis revealed that FUS expression is inversely correlated with Gleason grade, demonstrating that patients with high levels of FUS survived longer and were less likely to have bone metastases, suggesting that loss of FUS expression may contribute to cancer progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176904.RAWBXmdc7sVi2mO4KU9-iPg9CWDsu5eB0LiLxDUra7GSo130_provenance.
- NP176905.RAcwIfj4SZlrDNc4FWf-e_5pDx35rU4yAcrNpx9pSfEfc130_assertion description "[Juvenile neuronal ceroid-lipofuscinosis (Batten disease): a brief review and update.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176905.RAcwIfj4SZlrDNc4FWf-e_5pDx35rU4yAcrNpx9pSfEfc130_provenance.
- NP176910.RAeHtK7cKegPG2k8A8oTstyS4c7JklJRMP9KX3bWNPplE130_assertion description "[The strong association between smoking and EADC was seen preferentially in patients with the active allele of either GSTM1 (OR 7.9, 95% CI 1.14-54.76; P=0.003) or GSTT1 (OR 3.2, 95% CI 1.23-8.35; P=0.004).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176910.RAeHtK7cKegPG2k8A8oTstyS4c7JklJRMP9KX3bWNPplE130_provenance.
- NP176925.RAWje4aFJu95yUXRBEyVwpnKAyUM1xVHndu73pNTkmN9A130_assertion description "[A case of hairy cell leukemia with CCND1-IGH@ translocation: indolent non-nodal mantle cell lymphoma revisited.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176925.RAWje4aFJu95yUXRBEyVwpnKAyUM1xVHndu73pNTkmN9A130_provenance.
- NP176928.RATaU6tOUwG7qqMHDji5fd6I3DOEaeH5aFCKxgasCQg0s130_assertion description "[Expression of the 4 C-C chemokines monocyte chemoattractant protein 1 (MCP-1), macrophage inflammatory protein 1alpha (MIP-1alpha), MIP-1beta, and RANTES, and their receptors CCR-2 and CCR-5, was assessed in 11 OA patients and 5 normal controls, by reverse transcriptase-polymerase chain reaction (RT-PCR), enzyme-linked immunosorbent assay (ELISA), immunochemistry, and flow cytometry on untreated or interleukin-1beta (IL-1beta)- and/or tumor necrosis factor alpha (TNFalpha)-stimulated chondrocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176928.RATaU6tOUwG7qqMHDji5fd6I3DOEaeH5aFCKxgasCQg0s130_provenance.
- NP176930.RAYdtVAd-4xKVTU6nZ5ca9ox2AqlMYXg82Ec_kQO6CQzc130_assertion description "[In particular, Gal-3 in the nucleus plays a pivotal role in the regulation of cancer-related gene expression, including cyclin D1, TTF-1 and MUC2, presumably associated with tumor progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176930.RAYdtVAd-4xKVTU6nZ5ca9ox2AqlMYXg82Ec_kQO6CQzc130_provenance.
- NP176933.RAf_JpO-vnv_zOkt1O2Ozf-BSC6C1MtjQ0USb7uRI_5Ak130_assertion description "[The association analysis of RELN and GRM8 genes with autistic spectrum disorder in Chinese Han population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176933.RAf_JpO-vnv_zOkt1O2Ozf-BSC6C1MtjQ0USb7uRI_5Ak130_provenance.
- NP176945.RAdKlKKKsG4GhkVfZxB_D9BBJocRuhttokRMqoQ1eslnw130_assertion description "[The position of the polycystic kidney disease 1 (PKD1) gene mutation correlates with the severity of renal disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176945.RAdKlKKKsG4GhkVfZxB_D9BBJocRuhttokRMqoQ1eslnw130_provenance.
- NP176949.RAVhB77l0hFr66mdqu5HGsx1-5M6uGJQV4KI72KFpn_QY130_assertion description "[Tardive dyskinesia is not associated with the polymorphisms of 5-HT2A receptor gene, serotonin transporter gene and catechol-o-methyltransferase gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176949.RAVhB77l0hFr66mdqu5HGsx1-5M6uGJQV4KI72KFpn_QY130_provenance.
- NP176952.RAfInD66BiG5w8AOo-Xy6ZkH6oJUscOi9Ns-7x93jRlvE130_assertion description "[The mutant mice with deficiencies in expressing the Kir6.1 or the SUR1 gene are more vulnerable to generation of epileptic form of seizures, compared to wild-type controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176952.RAfInD66BiG5w8AOo-Xy6ZkH6oJUscOi9Ns-7x93jRlvE130_provenance.
- NP176957.RAZvfzpt7MiXrxFhNXdk6aPUO86aAsEN72sxLLGUhwkmE130_assertion description "[We conclude that blockade of microglial RAGE may have a beneficial effect on Abeta-mediated neuronal perturbation relevant to AD pathogenesis.-Fang, F., Lue, L.-F., Yan, S., Xu, H., Luddy, J. S., Chen, D., Walker, D. G., Stern, D. M., Yan, S., Schmidt, A. M., Chen, J. X., Yan, S. S. RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176957.RAZvfzpt7MiXrxFhNXdk6aPUO86aAsEN72sxLLGUhwkmE130_provenance.
- NP176960.RAdwHEQiACYCi32ObIz0nYb99C0Jp51RHRL5iebt260ZA130_assertion description "[An attenuated strain of Salmonella typhi delta(cya) delta(crp-cdt) delta(asd) expressing a gene encoding a hepatitis B virus core-pre-S protein was tested in female adult volunteers for its ability to elicit a systemic and a mucosal immune response.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176960.RAdwHEQiACYCi32ObIz0nYb99C0Jp51RHRL5iebt260ZA130_provenance.
- NP176964.RAdy1inoS-9sDH1GENqrntjnw-nC_QgPdX0kuFCMPcXK4130_assertion description "[These data provide evidence of the existence of a subtype-specific anti-NS5 response in the circulation of patients with chronic hepatitis C.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176964.RAdy1inoS-9sDH1GENqrntjnw-nC_QgPdX0kuFCMPcXK4130_provenance.
- NP176977.RAe_iHkAN26y2-Eb7HRfjLT6IcNbcfa1TT-Kspze1R-ws130_assertion description "[To investigate the DYT1 gene mutation in Chinese ethnic, we examined a series of 200 patients with primary dystonias (11 familial and 189 sporadic), 53 of their asymptomatic relatives, 97 patients with familial or early-onset parkinsonism, and 200 healthy subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176977.RAe_iHkAN26y2-Eb7HRfjLT6IcNbcfa1TT-Kspze1R-ws130_provenance.
- NP176986.RATpMTrnMm-zmTVAmgNRf-70wQ-oNSlITirOUTDkin0ic130_assertion description "[Pyruvate dehydrogenase complex (PDC) deficiency is a genetic mitochondrial disorder commonly associated with lactic acidosis, progressive neurological and neuromuscular degeneration and, usually, death during childhood.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176986.RATpMTrnMm-zmTVAmgNRf-70wQ-oNSlITirOUTDkin0ic130_provenance.
- NP176987.RARG_OVeXuoUgOj88X5cbZuCTQM4zaNa4rt6LJu6HhqFo130_assertion description "[Plasma homocysteine, MTHFR gene mutation, and open-angle glaucoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176987.RARG_OVeXuoUgOj88X5cbZuCTQM4zaNa4rt6LJu6HhqFo130_provenance.
- NP176991.RAWUao2kxgXpKBi43zbMssnRqnw_BZlPsnw4zUjxEf-Ms130_assertion description "[This case-control study suggests a contribution of CYP2E1, CYP2D6, and GSTM1 `null` variants to the development of acute leukemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176991.RAWUao2kxgXpKBi43zbMssnRqnw_BZlPsnw4zUjxEf-Ms130_provenance.
- NP176992.RAbHkwG5hXYyEMatM0OnVa9WN9g_CyWruH6YiB9Jf3C10130_assertion description "[To evaluate the anti-cancer effects of folic acid at the molecular level, we determined plasma folic acid concentration by radioimmuno-assay and the degree of total genomic DNA methylation by incubating DNA with 3H-S-adenosylmethionine (3H-SAM) in the presence of a methylase, and analyzed the methylation status of the c-myc and c-Ha-ras oncogenes by Southern blotting in 21 patients with advanced gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176992.RAbHkwG5hXYyEMatM0OnVa9WN9g_CyWruH6YiB9Jf3C10130_provenance.
- NP176996.RAeu7JeCP40hIM8AdLQ47K1A3gQsv663QTwZfCzN0uILk130_assertion description "[IL-18 induced phosphorylation of JNK, PKCdelta, p38 MAPK, and activating transcription factor 2 (ATF-2) in RA ST fibroblasts in a time-dependent manner, with JNK-2 being upstream of PKCdelta, ATF-2, and NFkappaB.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176996.RAeu7JeCP40hIM8AdLQ47K1A3gQsv663QTwZfCzN0uILk130_provenance.
- NP176997.RAe09swsdL66mhxdLEfm7MpCyl-S0BjfZm20nQoHXpdEU130_assertion description "[The first locus for familial combined hyperlipidemia on 1q21-23 revealed a gene encoding a transcription factor critical in lipid and glucose metabolism, USF1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP176997.RAe09swsdL66mhxdLEfm7MpCyl-S0BjfZm20nQoHXpdEU130_provenance.
- NP177004.RAYmYfko4VDl9nSQqv1KbkOyNSeuXa7SJGRl9xO41GaM8130_assertion description "[Targeting the interaction between OPN and alphavbeta3 integrin could be effective for future development of anti-angiogenic therapeutic agents for patients with lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177004.RAYmYfko4VDl9nSQqv1KbkOyNSeuXa7SJGRl9xO41GaM8130_provenance.
- NP177007.RAXMC2BoiD5j6lJ5Uh9T5DFxqMCApaHhLC0vrkR_8QSDM130_assertion description "[Truncated granulocyte colony-stimulating factor receptors (G-CSF-Rs) are implicated in severe congenital neutropenia (SCN) and the consecutive development of acute myeloid leukemia (AML).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177007.RAXMC2BoiD5j6lJ5Uh9T5DFxqMCApaHhLC0vrkR_8QSDM130_provenance.
- NP177016.RAVcwGhR-EhGT0TNS6kc2JSxE860O_FV9-ikMUTW7qI1g130_assertion description "[These observations suggest clearly that skin fibroblasts from individuals with either a genetic predisposition to or a high risk of cancer may not exist in a preneoplastic or `initiated` state susceptible to oncogenic transformation by TPA alone and that the mechanism of genetically determined cancer induction may be different from that of chemical carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177016.RAVcwGhR-EhGT0TNS6kc2JSxE860O_FV9-ikMUTW7qI1g130_provenance.
- NP177017.RAcPhE_3QHwDCUwH2GeOs5LuMPYVyUvxPPcyjviUEfHOg130_assertion description "[This phenotype parallels that of patients with tumor induced osteomalacia (TIO), X-linked hypophosphatemic rickets (XLH), and fibrous dysplasia (FD), in whom elevated serum FGF23 levels are often observed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177017.RAcPhE_3QHwDCUwH2GeOs5LuMPYVyUvxPPcyjviUEfHOg130_provenance.
- NP177018.RAcaOQ1Q2ZqUNNGfJzhdsyVkwNp2pLjzDmdjNHB2Rp-Fo130_assertion description "[These had previously been characterized for mutations of APC, KRAS, and TP53 genes and for chromosomal abnormality by comparative genomic hybridization (CGH).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177018.RAcaOQ1Q2ZqUNNGfJzhdsyVkwNp2pLjzDmdjNHB2Rp-Fo130_provenance.
- NP177019.RARPdOGYu-I2kD1uo9zQV8FaDpnfewdbTPD4jsSIwV8Ws130_assertion description "[The former type is associated with the chromosomal translocations found in acute myeloid leukemia, such as the AML1/MTG8 in t(8;21) and PML/RAR alpha in t(15;17).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177019.RARPdOGYu-I2kD1uo9zQV8FaDpnfewdbTPD4jsSIwV8Ws130_provenance.
- NP177021.RAYOLNcXQ058t8lqM7jmm6nfiEpJ688yzLQ8iRa4dv6gg130_assertion description "[Comparative genomic hybridization (CGH) and focused molecular genetic analyses demonstrated gains of chromosomes 7, losses of chromosomes 9 and 10, as well as homozygous deletion of p14(ARF) in one of the tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177021.RAYOLNcXQ058t8lqM7jmm6nfiEpJ688yzLQ8iRa4dv6gg130_provenance.
- NP177033.RAXeHYa33XZpRhOGmLASEE5vCkSHw230b6_AKQ8WAK_cY130_assertion description "[Use of transmitochondrial cybrids to assign a complex I defect to the mitochondrial DNA-encoded NADH dehydrogenase subunit 6 gene mutation at nucleotide pair 14459 that causes Leber hereditary optic neuropathy and dystonia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177033.RAXeHYa33XZpRhOGmLASEE5vCkSHw230b6_AKQ8WAK_cY130_provenance.
- NP177037.RAZrDDOPU1LengGcDtSJljvHvjnOzhMmKcqXxRMjUMNKM130_assertion description "[Taken together, these data suggest that EWS/FLI and NR0B1 physically interact, coordinately modulate gene expression, and mediate the transformed phenotype of Ewing's sarcoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177037.RAZrDDOPU1LengGcDtSJljvHvjnOzhMmKcqXxRMjUMNKM130_provenance.
- NP177042.RAX-B0B7608gTHoaj5ViR43Qmy1xLPVlH5pmDw20M2Nkk130_assertion description "[At baseline, the common (DR1/10)-DQB1*05:01 haplotype (20.4%) and the (DR1/10)-DQB1*05:01/DRB1*04:01-DQB1*03:02 genotype (8.7%) were independently associated with cardiovascular disease in all kidney status groups, except in patients with normal AER.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177042.RAX-B0B7608gTHoaj5ViR43Qmy1xLPVlH5pmDw20M2Nkk130_provenance.
- NP177043.RARdGdxETIcOU7LA-aRGLj3pGopBNBgaPDsCz2ZvLmEXo130_assertion description "[Antisense mRNA in situ hybridization and immunoblotting confirmed LCHN expression to be induced in the rat hippocampus following transient forebrain ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177043.RARdGdxETIcOU7LA-aRGLj3pGopBNBgaPDsCz2ZvLmEXo130_provenance.
- NP177056.RAUs-QfvpzJurVRGKVMV05W7pG8YEupqEhxEKMpDpC-Ck130_assertion description "[Recently, we have identified an allelic variant of human CN1 (hCN1) that results in increased enzyme activity and is associated with susceptibility for diabetic nephropathy in human diabetic patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177056.RAUs-QfvpzJurVRGKVMV05W7pG8YEupqEhxEKMpDpC-Ck130_provenance.
- NP177058.RAQMRBpID5S5P7xfbWQMOvy4VVnFw5ijKle1LTWsddgIU130_assertion description "[Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177058.RAQMRBpID5S5P7xfbWQMOvy4VVnFw5ijKle1LTWsddgIU130_provenance.
- NP177059.RAfPQsDVhtWF6aJEfNuBiyzhW-mmsC-QTD_gevcZmDwN4130_assertion description "[Microsomal triglyceride transfer protein (MTP) polymorphism modulates lipoprotein metabolism in the general population and liver disease in NASH; a functional MTP polymorphism recently predicted incident diabetes independently of insulin resistance in the general population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177059.RAfPQsDVhtWF6aJEfNuBiyzhW-mmsC-QTD_gevcZmDwN4130_provenance.
- NP177065.RAZLGab74muJ62TWw0FpPjKX6fT5UAkAjEztVEy3BB6PY130_assertion description "[Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177065.RAZLGab74muJ62TWw0FpPjKX6fT5UAkAjEztVEy3BB6PY130_provenance.
- NP177066.RAWOo7jneqLpU_-BxFRCY375LlvRC_Es0GdPxT0EZTgaY130_assertion description "[The TNFalpha-308 allele A frequency was significantly lower in AAH group (0.09), than cirrhosis (0.28) (p < 0.001), and healthy groups (p < 0.001).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177066.RAWOo7jneqLpU_-BxFRCY375LlvRC_Es0GdPxT0EZTgaY130_provenance.
- NP177069.RAYfkcCAdw1KEe7pE60COM6oK3I5rDqISPFZrG54gYdGY130_assertion description "[Cathepsin D specifically cleaves the chemokines macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-1 beta, and SLC that are expressed in human breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177069.RAYfkcCAdw1KEe7pE60COM6oK3I5rDqISPFZrG54gYdGY130_provenance.
- NP177070.RAUtCIzNRBCGQy35O74bh81sAu3LXxnJSrBoJPZV9zAZ8130_assertion description "[We found evidence, which was based on both one locus and two-loci genotype analyses, that low SES and DRD4 long and 5-HTTLPR long alleles, both alone and in interaction, are associated with higher aggressive behavior scores.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177070.RAUtCIzNRBCGQy35O74bh81sAu3LXxnJSrBoJPZV9zAZ8130_provenance.
- NP177074.RAXXW8uKd6oKy4R91GDAwiQ3ukKSktr3D63W__DDqTDss130_assertion description "[In conclusion, our data indicate that GALNT2 is down-regulated in patients with type 2 diabetes and suggest that this association is, at least partly, secondary to hyperglycemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177074.RAXXW8uKd6oKy4R91GDAwiQ3ukKSktr3D63W__DDqTDss130_provenance.
- NP177075.RAb6o-_act6hkEKfuIDuECZ1b2g8Y-v1wJbiCaJuItnsU130_assertion description "[CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177075.RAb6o-_act6hkEKfuIDuECZ1b2g8Y-v1wJbiCaJuItnsU130_provenance.
- NP177086.RAZ4zbFjVb9C38knkrjEWDB7eeBvp6FfYu9CkqKLuAHTA130_assertion description "[We searched for alterations in the catalytic domain of PI3K (PIK3CA), PTEN and KRAS, all of which may contribute to PI3K/AKT pathway activation, in a total of 160-familial colorectal (CRC) and endometrial carcinomas (EC), stratified by the presence vs. absence of germline mutations in DNA mismatch repair (MMR) genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177086.RAZ4zbFjVb9C38knkrjEWDB7eeBvp6FfYu9CkqKLuAHTA130_provenance.
- NP177090.RAePjn4paxj-Pgti5EdzMhO4k59FbXMMHJbRIAgO7aUmY130_assertion description "[Taken together, these results provide further support for an important role of AP-1-mediated transcription in some of the behavioral and molecular mechanisms underlying cocaine addiction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177090.RAePjn4paxj-Pgti5EdzMhO4k59FbXMMHJbRIAgO7aUmY130_provenance.
- NP177091.RAbqTkGyZkvNfsxEmW7evT2U8HfLLcUIWyWrEMvD_eUy8130_assertion description "[In addition, on comparison of Tumor-Node-Metastasis (TNM) classification groups, HAI-2 was also found to be statistically lower in the TNM 3 breast cancer group when compared with TNM groups 1 and 2, thus associated with a poor prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177091.RAbqTkGyZkvNfsxEmW7evT2U8HfLLcUIWyWrEMvD_eUy8130_provenance.
- NP177093.RAVkmzXEPMhht0pioJfiKbpa6raZSd1dR0gCl_07vX1Iw130_assertion description "[We found that SRE patterns have no difference between EGFR mutation positive and negative, and that the time from bone metastasis to the first SRE was longer in advanced lung adenocarcinoma patients with good PS and history of EGFR-TKI treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177093.RAVkmzXEPMhht0pioJfiKbpa6raZSd1dR0gCl_07vX1Iw130_provenance.
- NP177094.RAd2zRPt9VD_mTy1F0xgRIGWnKWjP5VqEQUl_brN5I_b8130_assertion description "[In this study, we used human gastric cancer cell lines to investigate whether TIMP-3 gene expression is suppressed in human gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177094.RAd2zRPt9VD_mTy1F0xgRIGWnKWjP5VqEQUl_brN5I_b8130_provenance.
- NP177095.RASiTQvjvW-AE_lbX-ePp9B6aVF2l7aVG14owDVeKmxeQ130_assertion description "[Since the correlation is not very strong, we have retrospectively analyzed the expression of E2F-1 in tumor samples or metastases from 25 patients with advanced colorectal cancer, homogeneously treated with an FU-based regimen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177095.RASiTQvjvW-AE_lbX-ePp9B6aVF2l7aVG14owDVeKmxeQ130_provenance.
- NP177100.RARQXW1-8KX-aROcal3XOFl9KfP-d6cEnuI1CqA9K0gQU130_assertion description "[To examine the contribution of environmental or endogenous mutagens other than UVR, which are expected to be relatively more important to the overall burden of NMSCs in the Japanese, we directly sequenced exons 5-8 of the p53 tumour suppressor gene in 29 Japanese patients with Bowen's disease, an in situ squamous-cell carcinoma of the skin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177100.RARQXW1-8KX-aROcal3XOFl9KfP-d6cEnuI1CqA9K0gQU130_provenance.
- NP177102.RAXErTzZHuc5NotuJQXptSpCLMMwc0QHFIRpzw34zVc4A130_assertion description "[The data provide a plausible explanation why therapy of malignant melanomas with alkylating anticancer drugs failed even in trials where the repair of the critical toxic lesion O(6)MeG was blocked by MGMT inhibitors and suggest approaches to abrogate intrinsic drug resistance by IFN and VPA-mediated reactivation of the death receptor pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177102.RAXErTzZHuc5NotuJQXptSpCLMMwc0QHFIRpzw34zVc4A130_provenance.
- NP177107.RAalOvq4FVauNmy3VDuVBpMyM-YEFug3dhexUQc1SWnzU130_assertion description "[This is the largest analysis of CYP1B1 mutations performed in European patients with PCG to date.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP177107.RAalOvq4FVauNmy3VDuVBpMyM-YEFug3dhexUQc1SWnzU130_provenance.