Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Xclaudin+1+is+required+for+proper+convergent+extension+movement+during+Xenopus+gastrulation. assertion.
- assertion asSentence Mutational+tuning+of+galectin-3+specificity+and+biological+function. assertion.
- assertion asSentence PAPC+mediates+these+functions+by+down-regulating+the+adhesion+activity+of+C-cadherin. assertion.
- assertion asSentence ET3%2FEdnrb2+signaling+is+required+for+melanoblast+migration+in+Ednrb2+gene-conserved+animals. assertion.
- assertion asSentence Morphogenesis+of+the+primitive+gut+tube+is+generated+by+Rho%2FROCK%2Fmyosin+II-mediated+endoderm+rearrangements. assertion.
- assertion asSentence Oct-25+stimulates+transcription+of+the+Xvent-2B+gene. assertion.
- assertion asSentence Tpt1+activates+transcription+of+oct4+and+nanog+in+transplanted+somatic+nuclei. assertion.
- assertion asSentence 40LoVe+binds+to+Vg1+mRNA+in+the+nucleus+and+remains+with+the+RNA+in+the+cytoplasm. assertion.
- assertion asSentence RGM+A+and+neogenin+have+important+functions+during+early+neural+development. assertion.
- assertion asSentence In+vivo+binding+of+U2AF%2865%29+to+a+polypyrimidine+tract+requires+a+flexible+RNA+backbone. assertion.
- assertion asSentence Necessary+for+the+migrations+of+massive+numbers+of+cells+during+gastrulation. assertion.
- assertion asSentence RNA+helicase+Ddx39+is+expressed+in+the+developing+central+nervous+system%2C+limb%2C+otic+vesicle%2C+branchial+arches+and+facial+mesenchyme+of+Xenopus+laevis. assertion.
- assertion asSentence Mcm2-7+associate+with+Cdc45+and+GINS+to+form+a+relatively+stable+CMG+%28Cdc45-MCM-GINS%29+complex. assertion.
- assertion asSentence Coordinated+interplays+between+Plx1+and+Gwl+are+required+for+reactivation+of+these+kinases+from+the+G%282%29%2FM+DNA+damage+checkpoint+and+efficient+checkpoint+recovery. assertion.
- assertion asSentence In+vivo+depletion+of+Nup155+led+to+failure+of+nuclear+lamina+formation+and+defects+in+chromosome+segregation+at+anaphase. assertion.
- assertion asSentence Gonadal+POMC+convertase+gene+expression+is+demonstrated+in+Xenopus+laevis. assertion.
- assertion asSentence Hoxb4+directly+induces+the+expression+of+FLASH%2C+a+component+of+the+FAS-CAPSASE8+apoptotic+pathway%2C+in+the+notochord+of+embryos+after+neurulation. assertion.
- assertion asSentence CENP-A+assembly+into+chromatin+requires+unidentified+deoxycytidine+deaminase+and+UNG2%2C+a+uracil+DNA+glycosylase+%28CENP-A%29. assertion.
- assertion asSentence Vg1+and+VegT+can+repress+the+ability+of+dorsal-animal+retinogenic+blastomeres+to+form+retina%2C+converting+the+lineage+from+neural%2Fretinal+to+non-neural+ectodermal+and+endo-mesodermal+fates. assertion.
- assertion asSentence Cep57%2FTranslokin+is+required+for+stable+microtubule+attachments+at+the+kinetochore+and+at+the+centrosome. assertion.
- assertion asSentence Weak-similarity+guanine+nucleotide+exchange+factor+%28WGEF%29mediates+Wnt-PCP+signalling+in+the+regulation+of+cell+movements+during+gastrulation. assertion.
- assertion asSentence Aurora-A+kinase+is+required+for+astral+microtubule+polymerization+and+spindle+microtubule+flux+during+chromosome+segregation. assertion.
- assertion asSentence Pituitary+adenylate+cyclase-activating+polypeptide+regulates+brain-derived+neurotrophic+factor+exon+IV+expression+through+the+VPAC1+receptor+in+the+amphibian+melanotrope+cell. assertion.
- assertion asSentence RGM+A+and+neogenin+have+important+functions+during+early+neural+development. assertion.
- assertion asSentence Dynein-dynactin+transports+the+essential+motor+Eg5+toward+the+spindle+poles+in+Xenopus+laevis+egg+extract+spindles%2C+revealing+a+direct+interplay+between+two+motors+of+opposite+directionality. assertion.
- assertion asSentence Work+links+the+onset+of+zygotic+gene+expression+in+the+Xenopus+embryo+with+the+translocation+of+Smicl+from+cytoplasm+to+nucleus%2C+the+phosphorylation+of+Rpb1+and+the+3%27-end+processing+of+newly+transcribed+mRNAs. assertion.
- assertion asSentence The+centrosomal+localization+of+Diversin+is+crucial+for+its+function+in+Wnt+signaling. assertion.
- assertion asSentence Pumilio+2+controls+translation+by+competing+with+eIF4E+for+7-methyl+guanosine+cap+recognition. assertion.
- assertion asSentence Unlike+other+CREB2+%28ATF4%29+proteins%2C+the+ATF4+isolated+from+the+gonads+of+Xenopus+embryos+contains+a+consensus+phosphorylation+site+for+protein+kinase+A+%28PKA%29. assertion.
- assertion asSentence GDF11+has+a+central+role+in+the+activation+of+Smad2+phosphorylation+in+tailbud+stage+Xenopus+embryos. assertion.
- assertion asSentence The+ubiquitin-conjugating+enzyme+UbcX+causes+the+ubiquitylation+of+XErp1%2C+followed+by+its+dissociation+from+the+anaphase-promoting+complex%2Fcyclosome. assertion.
- assertion asSentence Xpat+protein+has+an+important+role+in+Xenopus+germ+plasm+formation%2C+positioning+and+maintenance. assertion.
- assertion asSentence Affects+dynamics+of+the+actin+cytoskeleton%2C+signalling+from+Ral+to+RLIP+is+required+for+gastrulation. assertion.
- assertion asSentence Morphogenesis+of+the+primitive+gut+tube+is+generated+by+Rho%2FROCK%2Fmyosin+II-mediated+endoderm+rearrangements. assertion.
- assertion asSentence An+adhesion-independent%2C+aPKC-dependent+function+for+cadherins+in+morphogenetic+movements. assertion.
- assertion asSentence An+Aurora%2FPP1+phosphorylation+switch+modulates+CENP-E+motor+activity+as+a+feature+of+chromosome+congression+from+poles+and+localized+PP1+delivery+by+CENP-E+to+the+outer+kinetochore+is+necessary+for+stable+microtubule+capture+by+those+chromosomes. assertion.
- assertion asSentence Pitx+proteins+activate+Shroom3+transcription+and+Pitx-responsive+regulatory+elements+appeear+in+the+genomic+DNA+upstream+of+Shroom3+in+Xenopus. assertion.
- assertion asSentence RGS+proteins+maintain+robustness+of+GPCR-GIRK+coupling+by+selective+stimulation+of+the+G+protein+subunit+Galphao. assertion.
- assertion asSentence The+process+of+delimiting+the+three+germ+layers+requires+Notch+signaling. assertion.
- assertion asSentence ZFP423+coordinates+Notch1+and+bone+morphogenetic+protein+signaling%2C+selectively+up-regulating+Hes5+gene+expression. assertion.
- assertion asSentence Isoform+of+tumorhead+TH-B+variant+is+expressed+ubiquitously+throughout+development+from+early+cleavage+stages+until+at+least+the+tadpole+stage. assertion.
- assertion asSentence The+functions+of+Pum1+and+Pum2+in+translational+control+of+mRNAs+during+oocyte+maturation. assertion.
- assertion asSentence XFDL156+actively+restricts+mesodermal+differentiation+in+the+presumptive+ectoderm+by+controlling+the+spatiotemporal+responsiveness+to+p53. assertion.
- assertion asSentence Eg5+is+a+rate-limiting+component+of+the+cellular+machinery+that+drives+spindle+assembly+in+vertebrates. assertion.
- assertion asSentence Nudel+regulates+microtubule+organization+in+part+by+facilitating+assembly+of+the+lamin+B+spindle+matrix+in+a+dynein-dependent+manner. assertion.
- assertion asSentence Removal+of+Cdt1+from+chromatin+and+its+nuclear+exclusion+in+G2+is+critical+in+regulating+licensing+and+limiting+DNA+replication+in+S+phase+to+only+one+round. assertion.
- assertion asSentence Dynamic+interactions+of+high+Cdt1+and+geminin+levels+regulate+S+phase+in+early+Xenopus+embryos. assertion.
- assertion asSentence Xld+cleaves+Chordin%2C+an+inhibitory+binding+protein+for+BMP2%2F4%2C+releasing+fragments+with+reduced+affinity+for+these+important+ventralizing+signals. assertion.
- assertion asSentence Anti-dorsalizing+morphogentic+protein+%28ADMP%29plays+an+essential+role+in+the+regulation+of+body+pattern+formation+in+Xenopus. assertion.
- assertion asSentence Pitx1+is+expressed+in+hindlimbs+and+expression+is+similar+in+both+developing+and+regenerating+limb+buds. assertion.
- assertion asSentence Fullback+and+fullback-like+have+different+functions+from+p75NTR+during+early+development. assertion.
- assertion asSentence The+Fanconi+anemia+protein+FANCM+is+controlled+by+FANCD2+and+the+ATR%2FATM+pathways. assertion.
- assertion asSentence In+the+developing+diencephalon%2C+Caspase3+acts+downstream+of+Barhl2+in+limiting+neuroepithelial+cell+proliferation+by+inhibiting+beta-catenin+activation. assertion.
- assertion asSentence Kazrin+and+its+associating+ARVCF-+and+delta-catenins%2C+are+required+to+form+craniofacial+tissues+originating+from+cranial+neural+crest+and+precordal+plate. assertion.
- assertion asSentence Chk1+is+activated+at+the+midblastula+transition+in+Xenopus+laevis+embryos+independently+of+DNA+content+and+the+cyclin+E%2FCdk2+developmental+timer. assertion.
- assertion asSentence Cut5+plays+a+crucial+role+in+the+initial+amplification+step+of+the+ATR-Chk1+signaling+pathway+at+the+stalled+replication+fork. assertion.
- assertion asSentence Provide+high-resolution+structural+information+concerning+type+II+PABPs+and+an+example+of+a+single+RRM+domain+protein+that+transitions+from+a+homodimer+to+a+monomer+upon+RNA+binding. assertion.
- assertion asSentence Karyokinesis+of+early+embryonic+cells+are+regulated+by+unique+mechanisms+in+which+the+Xtr+protein+is+involved. assertion.
- assertion asSentence Establishes+the+identity+of+the+anterior+prechordal+mesoderm+within+Spemann%27s+organizer+by+inhibiting+the+formation+of+neighboring+tissues. assertion.
- assertion asSentence TopBP1+and+DNA+polymerase-alpha+directly+recruit+the+9-1-1+complex+%28rad9-rad1-Hus1%29+to+stalled+DNA+replication+forks. assertion.
- assertion asSentence Over-expression+leads+to+an+expansion+and+disorganisation+of+the+neural+crest+domain. assertion.
- assertion asSentence Xenopus+C%2FEBP+delta+plays+a+role+in+apoptotic+cell+death+of+larval-type+epithelium+during+the+stomach+remodeling. assertion.
- assertion asSentence The+higher+presence+of+p27BBP%2FeIF6+would+appear+related+to+an+increased+need+of+apoptosis+control+in+the+regions+where+cell+death+is+essential+for+normal+development. assertion.
- assertion asSentence XlMyo1c+couples+polymerizing+actin+to+membranes+and+so+mediates+force+production+during+compensatory+endocytosis. assertion.
- assertion asSentence Endogenous+SMC3+and+newly+expressed+hRAD21+co-localize+on+chromosomal+axes%2C+sites+where+sister+chromatids+are+tightly+paired.+hRAD21+recruitment+to+lampbrush+chromosomes+is+modulated+by+chromosomal+SMC1+and+SMC3. assertion.
- assertion asSentence XMeis3+protein+knock+down+also+causes+a+loss+of+primary+neuron+and+neural+crest+cell+lineages%2C+without+altering+expression+of+Zic%2C+Sox+or+Pax3+genes. assertion.
- assertion asSentence The+kinase+SGK1+in+the+endoderm+and+mesoderm+promotes+ectodermal+survival+by+down-regulating+components+of+the+death-inducing+signaling+complex. assertion.
- assertion asSentence FGF-8b+spliceform+mediates+early+mesoderm+and+posterior+neural+tissue+formation+in+Xenopus. assertion.
- assertion asSentence XHRT1+plays+an+important+role+in+glomerular+development+and+early+proximodistal+patterning. assertion.
- assertion asSentence Morphogenesis+of+the+primitive+gut+tube+is+generated+by+Rho%2FROCK%2Fmyosin+II-mediated+endoderm+rearrangements. assertion.
- assertion asSentence Hoxd1+is+transcriptionally+induced+by+the+Wnt%2Fbeta-catenin+signaling+pathway+during+anteroposterior+patterning+of+the+neural+axis. assertion.
- assertion asSentence A+directional+Wnt%2Fbeta-catenin-Sox2-proneural+pathway+regulates+the+transition+from+proliferation+to+differentiation+in+the+retina. assertion.
- assertion asSentence Zic3+can+suppress+Wnt%2Fbeta-catenin+signaling+and+control+development+of+the+notochord+and+Spemann%27s+organizer. assertion.
- assertion asSentence The+archenteron+elongation+is+independent+of+Xdsh+signaling%2C+especially+during+the+second+half+of+gastrulation. assertion.
- assertion asSentence Wnt11-induced+polarized+accumulation+of+Frizzled7+and+Dishevelled+at+adherens+junctions+underlies+the+formation+and+maintenance+of+apicobasal+cell+polarity. assertion.
- assertion asSentence Knockdown+of+Oct91+inhibits+neural+induction+driven+by+either+Sox2+or+Sox3. assertion.
- assertion asSentence Direct+interaction+and+interdependence+between+the+Otx2+and+Sox2+proteins+coordinate+Rax+expression+in+eye+development%2C+providing+molecular+linkages+among+the+genes+responsible+for+ocular+malformation. assertion.
- assertion asSentence One+of+the+earliest+genes+expressed+in+the+presumptive+pancreatic+tissue. assertion.
- assertion asSentence Gene+expressionof+Prx6+increased+during+development%2C+especially+at+stages+33-43+during+formation+of+the+lungs. assertion.
- assertion asSentence Xwnt-11+mRNA+appears+in+polysomes+only+at+the+end+of+gastrula. assertion.
- assertion asSentence Polo-like+kinase+%28Plx1%29+phosphorylates+xTRF1+in+vitro. assertion.
- assertion asSentence Dmrt4+is+an+important+regulator+of+neurogenesis+in+the+olfactory+system+upstream+of+neurogenin+and+ebf2. assertion.
- assertion asSentence XPIASy+functions+as+an+essential+negative+regulator+of+the+XSmad2+pathway+to+ensure+proper+mesoderm+induction+at+the+appropriate+time+and+in+the+appropriate+region. assertion.
- assertion asSentence Urocortin+1+released+from+neurohemal+axon+terminals+in+the+pituitary+neural+lobe+functions+as+a+stimulatory+neurohormone+for+alpha-melanophore-stimulating+hormone+%28alpha+MSH%29+release+from+melanotrope+cells+of+the+pituitary+intermediate+lobe. assertion.
- assertion asSentence The+WDR5+is+essential+for+vertebrate+development%2C+in+that+WDR5-depleted+X.+laevis+tadpoles+exhibit+a+variety+of+developmental+defects+and+abnormal+spatial+Hox+gene+expression. assertion.
- assertion asSentence Both+B-Raf+and+c-Raf+are+required+for+Ras-induced+MEK1+and+p42+MAP+kinase+activation. assertion.
- assertion asSentence XPIASy+functions+as+an+essential+negative+regulator+of+the+XSmad2+pathway+to+ensure+proper+mesoderm+induction+at+the+appropriate+time+and+in+the+appropriate+region. assertion.
- assertion asSentence Rab3d+is+required+for+Xenopus+anterior+neurulation+by+regulating+Noggin+secretion. assertion.
- assertion asSentence BCL6+forms+a+complex+with+BCL6+corepressor+%28BCoR%29+on+the+promoters+of+selected+Notch+target+genes+such+as+enhancer+of+split+related+1. assertion.
- assertion asSentence Exp6+represents+the+first+example+of+a+strictly+developmentally+regulated+nuclear+transport+pathway. assertion.
- assertion asSentence ADAMTS1+negatively+modulates+FGF+signaling+in+the+Xenopus+embryo. assertion.
- assertion asSentence XBtg2+plays+an+essential+role+in+the+anterior+neural+development%2C+by+regulating+neural+cell+differentiation%2C+and%2C+independently%2C+cell+proliferation+and+survival. assertion.
- assertion asSentence XMeis3+protein+knock+down+also+causes+a+loss+of+primary+neuron+and+neural+crest+cell+lineages%2C+without+altering+expression+of+Zic%2C+Sox+or+Pax3+genes. assertion.
- assertion asSentence The+pax3+and+Pax7+paralogs+cooperate+in+neural+and+neural+crest+patterning+using+distinct+molecular+mechanisms%2C+in+Xenopus+laevis+embryos. assertion.
- assertion asSentence Expressed+in+mesoderm+of+gastrulsa+stage+embryo+and+its+expression+is+regulated+by+both+beta-Catenin+and+Nodal-related+signals. assertion.
- assertion asSentence Interaction+of+xFADD+and+xRIP1+induced+synergistic+activation+of+JNK+and+NF-kappaB. assertion.
- assertion asSentence Vg1+is+an+essential+maternal+regulator+of+embryonic+patterning. assertion.
- assertion asSentence Vg1+and+VegT+can+repress+the+ability+of+dorsal-animal+retinogenic+blastomeres+to+form+retina%2C+converting+the+lineage+from+neural%2Fretinal+to+non-neural+ectodermal+and+endo-mesodermal+fates. assertion.
- assertion asSentence Ectodermin+is+a+key+switch+in+the+control+of+TGF-beta+gene+responses+during+early+embryonic+development+and+cell+proliferation. assertion.
- assertion asSentence HSN2+is+a+nervous+system-specific+exon+of+the+WNK1+gene+%28WNK1%2FHSN2+isoform%29. assertion.