Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Thyroid+hormone+receptor+beta+2+mRNA+is+more+abundant+in+the+pituitary+of+newly+hatched+chicks+than+in+15-day-old+embryos. assertion.
- assertion asSentence Src+is+expressed+in+spinal+lateral+motor+neurons+of+chick+embryo+at+the+time+of+limb+trajectory+selection. assertion.
- assertion asSentence IL-6+stimulates+the+2-deoxyglucose+uptake+through+p44%2F42+MAPKs+activation+via+Ca%282%2B%29%2FPKC+and+EGF+receptor+in+primary+cultured+chicken+hepatocytes. assertion.
- assertion asSentence In+calvarial+bone+explants+egg+white+cystatin+decreases+calcium+release+into+the+medium+significantly. assertion.
- assertion asSentence The+expression+of+c-fos+in+the+optokinetic+nuclei+is+linked+to+near+peak+firing+rates+and+the+novelty+and+duration+of+the+visual+signals%2C+supporting+the+assumption+that+expression+is+related+to+stimulus+contexts+leading+to+neuronal+plastic+changes. assertion.
- assertion asSentence FGFR3+signaling+is+required+for+the+elongation+of+Meckel%27s+cartilage+and+during+intramembranous+ossification+of+mandibular+bones. assertion.
- assertion asSentence The+tight+association+of+helix+B+with+the+E+and+F+helices+in+the+Ca%282%2B%29-bound+state+is+lost+upon+removal+of+Ca%282%2B%29%2C+producing+a+deep+hydrophobic+cavity. assertion.
- assertion asSentence Octanoate+reduced+VLDL+secretion+by+the+specific+down-regulation+of+apoB+gene+expression+and+impairment+of+subsequent+synthesis+of+apoB%2C+not+by+the+modulation+of+intracellular+apoB+degradation. assertion.
- assertion asSentence Epistatic+effects+between+ApoB+and+UCP+is+associated+with+abdominal+fat+trait+in+chicken. assertion.
- assertion asSentence Interaction+of+steroid+receptorss+with+chicken-transfected+hsp90+is+minimal+when+compared+to+a+bona+fide+type+of+interaction%2C+with+the+co-factors. assertion.
- assertion asSentence Neuropeptide+Y+content+in+chick+embryo+hypothalamus+during+development. assertion.
- assertion asSentence POLQ+and+POLbeta+share+an+overlapping+function+in+the+repair+of+oxidative+base+damage. assertion.
- assertion asSentence The+ability+of+supplementation+of+Freund+adjuvant+to+enhance+the+quantity+of+specific+immunoglobulin+Y+in+eggs+of+laying+hens. assertion.
- assertion asSentence IL-6+stimulates+the+2-deoxyglucose+uptake+through+p44%2F42+MAPKs+activation+via+Ca%282%2B%29%2FPKC+and+EGF+receptor+in+primary+cultured+chicken+hepatocytes. assertion.
- assertion asSentence Akt+activity+can+regulate+growth+cone+expansion+via+localized+Rac1+signaling+and+regulate+axonal+branching+and+soma+size+via+activation+of+mTOR. assertion.
- assertion asSentence %28PSD-95%29PSD-95+family+members+at+nicotinic+synapses+on+chick+ciliary+ganglion+neurons+in+culture+execute+multiple+functions+to+enhance+transmission. assertion.
- assertion asSentence THRSPalpha+locus+is+associated+with+abdominal+fat+traits+in+a+broiler+x+Leghorn+resource+population. assertion.
- assertion asSentence In+the+chick+embryo%2C+kif5c+plays+a+role+during+different+morphogenetic+processes. assertion.
- assertion asSentence The+two-dimensional+%282D%29+and+three-dimensional+%283D%29+structures+of+chicken+major+histocompatibility+complex+%28MHC%29+class+I+protein+%28BF2+and+beta2m%29were+elucidated. assertion.
- assertion asSentence Cad7+and+Cad6B+differentially+regulate+cranial+motoneuron+growth%2C+branching+and+axon+guidance. assertion.
- assertion asSentence A+unique+motif+in+the+occludin+sequence+that+is+involved+in+the+regulation+of+ZO-1+binding+by+reversible+phosphorylation+of+specific+Tyr+residues. assertion.
- assertion asSentence Nucleotide+receptor+TLR21+senses+and+responds+to+DNA%2C+despite+low+sequence+similarity+with+the+functionally+related+mammalian+TLR9. assertion.
- assertion asSentence ADAM19+plays+an+important+role+in+the+embryonic+development+of+chicken. assertion.
- assertion asSentence Important+for+digestive+organ+development%2C+particularly+for+epithelial+differentiation. assertion.
- assertion asSentence TRIM41+expressed+in+testes%2C+bursa%2C+thymus+and+%28unlike+TRIM27%29+in+spleen. assertion.
- assertion asSentence Wdr5+is+required+for+endochondral+bone+formation. assertion.
- assertion asSentence Chickens+sense+lipopolysaccharide+via+orthologs+of+mammalian+TLR4+rather+than+via+the+previously+implicated+chicken+TLR2+isoform+type+2+receptor. assertion.
- assertion asSentence Nel+interacts+with+a+range+of+molecules+through+its+different+domains+and+exerts+distinct+functions. assertion.
- assertion asSentence Polymorphisms+within+the+IGF1+gene+are+associated+with+5-week+body+weight. assertion.
- assertion asSentence High+pleiotrophin+is+associated+with+ovarian+carcinomas. assertion.
- assertion asSentence Activation-induced+cytidine+deaminase+targets+all+genes+expressed+in+mutating+B+cells+that+are+associated+with+CAGGTG+motifs+in+the+appropriate+context. assertion.
- assertion asSentence SHOX+upstream+deletions+occur+at+a+lower+frequency+because+of+the+structural+organization+of+this+genomic+region. assertion.
- assertion asSentence Avian+renal+proximal+tubule+epithelium+urate+secretion+is+mediated+by+Mrp4. assertion.
- assertion asSentence A+Stim1-dependent%2C+noncapacitative+Ca2%2B-entry+pathway+is+activated+by+B-cell-receptor+stimulation+and+depletion+of+Ca2%2B. assertion.
- assertion asSentence GHRH+increases+growth+hormone+gene+expression+in+retinal+cells. assertion.
- assertion asSentence Intronic+deletions+of+the+tva+receptor+gene+decreased+susceptibility+to+infection+by+avian+sarcoma+and+leukosis+virus+subgroup+A. assertion.
- assertion asSentence Chickens+sense+lipopolysaccharide+via+orthologs+of+mammalian+myeloid+differentiation+protein-2+%28MD-2%2FLY96%29+rather+than+the+previously+implicated+chicken+TLR2+isoform+type+2+receptor. assertion.
- assertion asSentence Non-conserved+roles+for+ATX+during+neural+development+and+organogenesis. assertion.
- assertion asSentence Cdk6+up-regulation+in+TDP-43-depleted+cells+is+accompanied+by+an+increase+in+phosphorylation+of+two+of+its+major+targets%2C+the+retinoblastoma+protein+pRb+and+pRb-related+protein+pRb2%2Fp130. assertion.
- assertion asSentence RIM%2Frab3A+and+N+type+Ca2%2B+channels%2FCaV2.2+co-localize+at+a+presynaptic+transmitter+release+fate+in+chicken+brain+synaptosomes. assertion.
- assertion asSentence Calcineurin+homologous+protein+plays+an+essential+role+in+stabilizing+NHE-1+%28Na%2B%2FK%2B+exhanger+isoform+1%29. assertion.
- assertion asSentence CAPN3+polymorphisms+are+strongly+associated+with+chicken+carcass+traits. assertion.
- assertion asSentence Spinal+cord+overexpression+of+Hsp70+enhances+motor+neuron+survival+in+vivo+during+the+period+of+naturally+occurring+cell+death. assertion.
- assertion asSentence ATM+and+ATR+control+mitotic+events+in+vertebrate+cells+by+targeting+CEP63+and+centrosome+dependent+spindle+assembly. assertion.
- assertion asSentence Conserved+developmental+stage-+and+tissue-specific+alternative+splicing+of+MBNL+transcripts+is+an+important+mechanism+by+which+MBNL+activity+is+regulated+during+embryonic+development. assertion.
- assertion asSentence The+chicken+ADAM12+is+expressed+exclusively+in+tissues+and+organs+derived+from+the+neural+tube%2C+the+neural+crest+or+the+mesoderm%2C+with+a+highly+regulated+spatiotemporal+expression+pattern. assertion.
- assertion asSentence The+expression+of+SLC27A1+mRNA+in+chicken+tissues+exhibits+specific+developmental+changes+and+age-related+patterns. assertion.
- assertion asSentence ADP+plays+an+important+role+in+fat+development. assertion.
- assertion asSentence Coevolution+between+class+I+and+TAP+genes+can+explain+the+presence+of+a+single+dominantly+expressed+class+I+molecule+in+common+chicken+MHC+haplotypes. assertion.
- assertion asSentence SLC41A2+is+expressed+in+both+wild-type+%26+TRPM7-deficient+DT40+cells.+heterologously+expressed+SLC41A2+protein+is+plasma-membrane+protein+with+N-terminus-outside%2FC-terminus-inside+11-TM+span+topology%2C+functioning+as+trans-plasma-membrane+transporter. assertion.
- assertion asSentence GAP-43+expression+in+the+adult+and+developing+oscine+song+control+system. assertion.
- assertion asSentence Coexpression+of+Cx26%2FCx30+is+unique+to+gap+junctions+in+the+vertebrate+inner+ear. assertion.
- assertion asSentence Peroxisome+proliferator-activated+receptor+gamma+%28PPARgamma%29+mediates+a+Ski+oncogene-induced+shift+from+glycolysis+to+oxidative+energy+metabolism. assertion.
- assertion asSentence The+expression+of+Cyp26B1+does+not+overlap+with+expression+of+chick+Cyp26A1%2C+both+of+which+are+retinoic+acid+catabolizing+enzymes. assertion.
- assertion asSentence NOGO-A+is+up-regulated+by+FGF4+during+brain+development. assertion.
- assertion asSentence Epigenetic+changes+within+the+ABCA1+gene+promoter+contribute+to+the+interindividual+variability+in+plasma+HDL-C+%28high-density+lipoproteins+cholesterol%29+concentrations+and+are+associated+with+coronary+artery+disease+expression. assertion.
- assertion asSentence IL-18+and+IL-12+together+can+decrease+ABCA1+expression+and+cellular+cholesterol+efflux+in+THP-1+macrophage-derived+foam+cells+through+the+IL-18R%2FNF-kappaB+signaling+pathway. assertion.
- assertion asSentence The+two+critical+HLA+regions+for+susceptibility+to+autoimmune+pancreatitis+are+limited+to+the+HLA-DRB1%2A0405-DQB1%2A0401+in+the+class+II+and+the+ABCF1in+the+class+I+regions. assertion.
- assertion asSentence The+nucleotide+binding+domain+1+%28NBD1%29+of+the+retina-specific+ATP-binding+cassette+transporter+is+a+general+ribonucleotidase+capable+of+binding+ATP%2C+CTP%2C+GTP+and+UTP. assertion.
- assertion asSentence ABCA4+microarray+screening+is+usually+requested+in+daily+clinical+practice+to+strengthen+the+diagnosis+when+the+disease+is+atypical. assertion.
- assertion asSentence ABCA4+gene+has+a+functional+role+in+the+development+of+orofacial+clefting+in+hispanic+population. assertion.
- assertion asSentence Expression+of+BCR%2FABL+and+BCL-2+in+myeloid+progenitors+leads+to+myeloid+leukemias. assertion.
- assertion asSentence MCL-1+is+a+BCR%2FABL-dependent+survival+factor+and+interesting+target+in+chronic+myeloid+leukemia. assertion.
- assertion asSentence Abi-1-mediated+coupling+of+Abl+to+WAVE2+promotes+Abl-evoked+WAVE2+tyrosine+phosphorylation+required+to+link+WAVE2+with+activated+Rac+and+with+actin+polymerization+and+remodeling+at+the+cell+periphery. assertion.
- assertion asSentence Along+with+BCR%2C+deleted+in+leukemia%2C+myeloid%2C+philadelphia-positive. assertion.
- assertion asSentence A+mechanism+for+how+Crk-II+functions+in+the+transactivation+of+the+Abl+tyrosine+kinase. assertion.
- assertion asSentence BCR%2FABL+induces+SPK1+expression+and+increases+its+cellular+activity%2C+leading+to+upregulation+of+Mcl-1+in+CML+cells. assertion.
- assertion asSentence The+activation+of+WAVE3+to+promote+actin+remodeling+is+enhanced+by+the+c-Abl-mediated+tyrosine+phosphorylation+of+WAVE3. assertion.
- assertion asSentence Crystal+structure+of+the+T315I+Abl+mutant+in+complex+with+the+aurora+kinases+inhibitor+PHA-739358. assertion.
- assertion asSentence Nuclear+c-Abl+kinase+can+activate+CSF-1+gene+transcription+by+regulating+AP-1+activity+in+the+signaling+events+induced+by+L-selectin+ligation. assertion.
- assertion asSentence ABL+kinase+domain+pseudoexon+insertion+is+not+uncommon+in+BCR-ABL+transcripts. assertion.
- assertion asSentence BCR%2FABL+switch+on+backup+non-homologous+end+joining+%28B-NHEJ%29+which+is+more+error-prone+thann+DNA-PK%28CS%29+D-NHEJ+and+in+such+manner+contribute+to+the+increase+of+the+genomic+instability+of+leukemic+cells. assertion.
- assertion asSentence ABL+mutations+are+common+in+Chinese+imatinib-resistant+CML+patients+and+are+associated+with+clinical+resistance. assertion.
- assertion asSentence Physical+exercise+induced+significant+increases+in+BCR-ABL1+transcript+levels+concomitant+with+changes+in+leukocyte+content+of+peripheral+blood. assertion.
- assertion asSentence The+ABL-inhibitors+activate+MAPKs+in+CD34%2B+chronic+myelogenous+leukemia+progenitor+cells. assertion.
- assertion asSentence Individuals+carrying+the+645Asp+amino+acid+displayed+lower+serum+diamine+oxidase+activity+as+compared+with+noncarriers+%28P%3C0.001%29+with+a+significant+gene-dose+effect+%28P%3C0.05%29. assertion.
- assertion asSentence An+aspartic+acid+residue%2C+conserved+in+all+diamine+oxidases%2C+is+responsible+for+the+diamine+specificity+by+interacting+with+the+second+amino+group+of+preferred+diamine+substrates. assertion.
- assertion asSentence Low+serum+diamine+oxidase+activity+in+inflammatory+bowel+disease. assertion.
- assertion asSentence The+highest+Arg+transcript+and+protein+levels+are+in+the+mature+B+cells. assertion.
- assertion asSentence Substitution+of+M214+can+cause+alternative+conformation. assertion.
- assertion asSentence High+E-selectin+and+CA19-9+is+associated+with+colorectal+cancer. assertion.
- assertion asSentence Metabolic+regulation+of+invadopodia+and+invasion+by+acetyl-CoA+carboxylase+1+and+de+novo+lipogenesis. assertion.
- assertion asSentence Acetyl-CoA+carboxylase+beta+%28ACC2%29+plays+a+key+role+in+fatty+acid+synthesis+and+oxidation+pathways. assertion.
- assertion asSentence SCAD+deficiency+should+be+considered+as+a+disorder+of+protein+folding+that+can+lead+to+clinical+disease+in+combination+with+other+genetic+and+environmental+factors. assertion.
- assertion asSentence SCAD+deficiency+cause+a+disorder+that+leads+to+the+accumulation+of+butyrylcarnitine+and+ethylmalonic+acid+in+blood+and+urine. assertion.
- assertion asSentence Missense+mutations+in+Very-Long-Chain+Acyl-CoA+Dehydrogenase+is+associated+with+inborn+errors+of+lipid+metabolism. assertion.
- assertion asSentence The+expressions+of+LCHAD+gene+and+protein+are+remarkably+reduced+in+early+onset+severe+preeclampsia+and+HELLP+syndrome. assertion.
- assertion asSentence Two+PKC+consensus+sites+on+human+acid-sensing+ion+channel+1b+differentially+regulate+its+function. assertion.
- assertion asSentence ASICs+are+leading+acid+sensors+in+human+nociceptors+and+VR1+participates+in+the+nociception+mainly+under+extremely+acidic+conditions. assertion.
- assertion asSentence Sulfhydryl+compounds+potentiate+H%28%2B%29-gated+currents+via+two+mechanisms%2C+metal+chelation+and+redox+modulation+of+target+amino+acids. assertion.
- assertion asSentence Spontaneous+currents+represent+activation+of+acid-sensitive+ion+channels+%28ASICs%29+by+autocrine+vesicular+release+of+protons+from+HEK+cells. assertion.
- assertion asSentence Differences+between+the+t+peptides+of+Aacetylcholinesterase+and+butyrylcholinesterase+are+conserved+among+all+vertebrates. assertion.
- assertion asSentence ACLY+is+a+positive+regulator+of+glycolysis+in+glioblastoma+cells. assertion.
- assertion asSentence A+phosphomimetic+mutation+at+Ser-138+renders+IRP1+sensitive+to+iron-dependent+degradation. assertion.
- assertion asSentence ATP%2FADP+binding+maintains+IRP-1+in+a+non-IRE-binding+state. assertion.
- assertion asSentence Binding+sites+for+recombinant+human+zona+pellucida+%28ZP%29+glycoproteins+located+at+the+N-+and+C-termini+of+proacrosin+reveal+a+key+role+of+the+proenzyme+in+the+interaction. assertion.
- assertion asSentence Manganese+acts+as+an+antagonist+of+iron%2C+disrupting+the+enzymatic+activity+and+gene+expression+of+mACON+and+citrate+metabolism+in+the+prostate. assertion.
- assertion asSentence Crystal+structure+of+the+second+human+low+molecular+weight+PTPase+isoenzyme+provides+the+opportunity+to+examine+the+structural+basis+of+different+substrate+and+inhibitor%2Factivator+responses. assertion.
- assertion asSentence There+is+a+significant+association+between+acid+phosphatase+locus+1+%28ACP%281%29+and+cancer+grade%2C+mainly+due+to+ACP%281%29+genotypes+carrying+the+%2AC+allele+that+are+much+less+represented+in+patients+with+low+grade+when+compared+with+those+with+high+grade. assertion.
- assertion asSentence In+human+serum%2C+TRACP+5b+circulates+in+a+large+complex+that+contained+alpha2M+and+calcium. assertion.