Nanopublications

Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }

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NP195080.RAUcrJBVmtICytV7pjYQLo4mF13ZCipao0V1BzE1nWIdw130_assertion description "[Our studies shed new light on the compartment-specific role of CTGF in mammary tumorigenesis, and provide novel insights into the mechanism(s) generating a lethal tumor microenvironment in patients lacking stromal Cav-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195080.RAUcrJBVmtICytV7pjYQLo4mF13ZCipao0V1BzE1nWIdw130_provenance.
NP195082.RAWZBcx9niiNLVKrdxvu6IIkeJr1m7uY5YcfB9gmv9Yyg130_assertion description "[The aim of the present study was to determine the relation of EPH tyrosine kinase receptor B2 (EPHB2) A9 region mutation and microsatellite instability (MSI); and to analyze their influence in prognosis of patients with sporadic colorectal cancer (CRC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195082.RAWZBcx9niiNLVKrdxvu6IIkeJr1m7uY5YcfB9gmv9Yyg130_provenance.
NP195092.RAc5aYU6cYn459YXqHGU0Zx7FUzZjoKbMFa1lr7c1zn04130_assertion description "[Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195092.RAc5aYU6cYn459YXqHGU0Zx7FUzZjoKbMFa1lr7c1zn04130_provenance.
NP195105.RAbAhzODnY173S2JlLLHamo13grmrBZ6pItX8xcKaN1VU130_assertion description "[Beta-thalassemia is a common monogenic disease caused by mutations in the human beta-globin gene (HBB), many of which are differentially represented in human subpopulations stratified by ethnicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195105.RAbAhzODnY173S2JlLLHamo13grmrBZ6pItX8xcKaN1VU130_provenance.
NP195109.RAbBr9vpx5TzqXm3ovCOwXbB52VOTDOcq5WT8qQDW9zkU130_assertion description "[The HLA class II gene HLA-DRB1*1101 was the strongest predictor of recurrence, and HLA-DRB1*1101-positive melanoma patients had increased levels of IFN-gamma compared with patients lacking the gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195109.RAbBr9vpx5TzqXm3ovCOwXbB52VOTDOcq5WT8qQDW9zkU130_provenance.
NP195115.RATCGMHFRkA6YtWmXFIKAOWxtnY5b2rQ86BotreHIACUM130_assertion description "[Subsequently, a couple of studies outside India investigated the FST gene for the presence of any mutations and its association with PCOS and the results were found to be largely inconsistent probably due to differences in the ethnic backgrounds and small sample sizes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195115.RATCGMHFRkA6YtWmXFIKAOWxtnY5b2rQ86BotreHIACUM130_provenance.
NP195116.RAYxUAn077OkgfQ1WfEz9ycjHic0WD30MB81sSHtTTJl8130_assertion description "[To investigate the utility of Co-hArgI for L-Arg depletion therapy in cancer we systematically investigated three strategies for enhancing the persistence of the enzyme in circulation: (i) site specific conjugation of Co-hArgI engineered with an accessible N-terminal Cys residue to 20kDa PEG-maleimide (Co-hArgI-C(PEG-20K)); (ii) engineering of the homotrimeric Co-hArgI into a linked, monomeric 110kDa polypeptide (Co-hArgI x3) and (iii) lysyl conjugation of 5kDa PEG-N-hydroxysuccinimide (NHS) ester (Co-hArgI-K(PEG-5K)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195116.RAYxUAn077OkgfQ1WfEz9ycjHic0WD30MB81sSHtTTJl8130_provenance.
NP195122.RAXbEeyIIc0DNXZFSPaSFbBf7zANA5SZFGQN47BSErtlU130_assertion description "[Taking these results together, we conclude that periostin plays a unique role as an inducer of chemokines to recruit neutrophils and macrophages important in the process of pulmonary fibrosis in BLM-administered model mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195122.RAXbEeyIIc0DNXZFSPaSFbBf7zANA5SZFGQN47BSErtlU130_provenance.
NP195128.RAcVJNdhSn8zMP5UUrnvGTkOu3txwGSHLqlRcYU0J2zw0130_assertion description "[We observed upregulated FGL2 expression in alveolar macrophages from peripheral lungs of chronic obstructive pulmonary disease (COPD) patients and found a correlation between FGL2 expression and increased macrophage activation markers (CD11b and CD14).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195128.RAcVJNdhSn8zMP5UUrnvGTkOu3txwGSHLqlRcYU0J2zw0130_provenance.
NP195129.RARpv7gTHdoUMcFBGP3nBjlebMx4LTJ2sOZKYJmxNIcig130_assertion description "[The homozygous deletion allele of the angiotensin converting enzyme gene (ACE/DD), homozygous threonine allele of the angiotensinogen gene (AGN/TT), and the epsilon4 allele of the apolipoprotein E gene (apoE/epsilon4) are reported to be associated with ischemic heart disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195129.RARpv7gTHdoUMcFBGP3nBjlebMx4LTJ2sOZKYJmxNIcig130_provenance.
NP195133.RAU5CBNBGhndbNU0CwKfAQnhyOjaDnksOb1caiAIzj9ac130_assertion description "[The DLBCL expressed CD19 and CD20, CD23, bcl-2, bcl-6, MUM1 and immunoglobulin κ light chain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195133.RAU5CBNBGhndbNU0CwKfAQnhyOjaDnksOb1caiAIzj9ac130_provenance.
NP195146.RAaXE3kDYcQgle9fa4Lwc6rtH_-KdXRZmDshVtFeOFsBU130_assertion description "[In order to test for the implication of MTS1 as a tumour suppressor gene in paediatric ALLs we have explored the 9p21 chromosomal region of 46 children with this disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195146.RAaXE3kDYcQgle9fa4Lwc6rtH_-KdXRZmDshVtFeOFsBU130_provenance.
NP195148.RAY4BFQkU8TxEq4l8xcTZJu1wIP_fECRwdqtaZ-HWrTcA130_assertion description "[To assess the contribution of embB306 mutations to EMB resistance, the EMB minimum inhibitory concentration (MIC) of these strains was determined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195148.RAY4BFQkU8TxEq4l8xcTZJu1wIP_fECRwdqtaZ-HWrTcA130_provenance.
NP195153.RAdG5CnGj-EWAchinfO6gYRKd6oAl78ma8sXSUVOaFVVc130_assertion description "[Role of RANKL-induced osteoclast formation and MMP-dependent matrix degradation in bone destruction by breast cancer metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195153.RAdG5CnGj-EWAchinfO6gYRKd6oAl78ma8sXSUVOaFVVc130_provenance.
NP195160.RAVJG3ZeQH-KUoR7L935lZiFbx88fG_W73PF9q9JfcRag130_assertion description "[Our results show that major differentiation factors of the NK-cell lineage, including HOXA9, HOXA10 and ID2, were (de)regulated via PRC2 which therefore contributes to T-cell leukemogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195160.RAVJG3ZeQH-KUoR7L935lZiFbx88fG_W73PF9q9JfcRag130_provenance.
NP195169.RATqKoBHXdX65Qi2-rb1Bvyb7U33AiwVAwlgsqnbhz8Jk130_assertion description "[Toward the future development of a defined subunit vaccine against leishmaniasis is, high levels of recombinant GP63 for diverse species of Leishmania were produced in Escherichia coli.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195169.RATqKoBHXdX65Qi2-rb1Bvyb7U33AiwVAwlgsqnbhz8Jk130_provenance.
NP195170.RAfu8Wc3bkfdaW4DVHIvffmpwhW_XHH-S_YSQaSH0YbBw130_assertion description "[The tumor suppressor protein PTEN is mutated in glioblastoma multiform brain tumors, resulting in deregulated signaling through the phosphoinositide 3-kinase (PI3K)-protein kinase B (PKB) pathway, which is critical for maintaining proliferation and survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195170.RAfu8Wc3bkfdaW4DVHIvffmpwhW_XHH-S_YSQaSH0YbBw130_provenance.
NP195173.RAfQAAsgYyutw1Dc_2cdrbTHWxGfpGD6SrtfOjEaQugD8130_assertion description "[Progress has been made in determining association of HLA class II DRB1, DQB1 and DQA1 loci with GD demonstrating a predisposing effect for DR3 (DRB1(*)03-DQB1(*)02-DQA1(*)05) and a protective effect for DR7 (DRB1(*)07-DQB1(*)02-DQA1(*)02).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195173.RAfQAAsgYyutw1Dc_2cdrbTHWxGfpGD6SrtfOjEaQugD8130_provenance.
NP195177.RASb2ET7YFcONqQPilpByFV5jq-t8_IbZgwHKkY_9PBXs130_assertion description "[This pilot study showed that CYP1B1 and PR polymorphisms, alone or in combination, might be associated with prostate cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195177.RASb2ET7YFcONqQPilpByFV5jq-t8_IbZgwHKkY_9PBXs130_provenance.
NP195179.RAUnJnHNkUCln6DQuLs-bVb5oEwq3IFgIawdfcnJmVkM4130_assertion description "[AGT and ACE genes influence classic mitral valve prolapse predisposition in Marfan patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195179.RAUnJnHNkUCln6DQuLs-bVb5oEwq3IFgIawdfcnJmVkM4130_provenance.
NP195187.RAXnlk9X0l1M1NOaJU_iVdFiZ0eZ4SnVBoHzCnSzt8KvI130_assertion description "[In addition, LPA enhanced the tumorigenesis/metastasis of ID8 cell in vivo as assessed by increased tumor size, early onset of ascites formation, and reduced animal survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195187.RAXnlk9X0l1M1NOaJU_iVdFiZ0eZ4SnVBoHzCnSzt8KvI130_provenance.
NP195188.RAVLqzfJQFMiMTQ7BxsLbDpLeNrMYg-n1t2nnl5ruJBK4130_assertion description "[To investigate the prevalence of potential mutations in the gene encoding HKII, we used the polymerase chain reaction (PCR) to amplify each of the 18 exons of the HKII gene from genomic DNA derived from 59 subjects: 25 insulin-resistant probands with clinical features of the type A syndrome and 34 NIDDM subjects enrolled in the United Kingdom Prospective Study of Therapies of NIDDM (UKPDS) who represented the highest percentile of fasting hyperinsulinemia in the UKPDS population of 5,098 subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195188.RAVLqzfJQFMiMTQ7BxsLbDpLeNrMYg-n1t2nnl5ruJBK4130_provenance.
NP195195.RAQ7E7bid5A_9XkPiadAqxVtqkrc0-Yn74iE5tPvfsTOc130_assertion description "[The overall MGMT promoter methylation rate was 30% in the de novo group and 80% in the tumor progression group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195195.RAQ7E7bid5A_9XkPiadAqxVtqkrc0-Yn74iE5tPvfsTOc130_provenance.
NP195196.RAbmdM332r83m-wGyNjqENSYj-q9Gq_rxlmyVI2-sNDCY130_assertion description "[The respective protective effect against obesity implies that variation in the MC4R gene entails both loss and gain of function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195196.RAbmdM332r83m-wGyNjqENSYj-q9Gq_rxlmyVI2-sNDCY130_provenance.
NP195207.RAWVSWGZcq2mg4L4s9oucMNPBExnyD7FiTv7MK4VZ_bBw130_assertion description "[Moreover, in patients with ErbB2-positive breast tumors, low PTPRO expression correlated with poor clinical prognosis compared to ErbB2-positive patients with high levels of PTPRO.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195207.RAWVSWGZcq2mg4L4s9oucMNPBExnyD7FiTv7MK4VZ_bBw130_provenance.
NP195208.RAULzsXolRYAhwlPhpAdR--H5puH3raU2lgjI9nEEymOY130_assertion description "[The predictive ability of the American Joint Committee on Cancer stage and of the concomitant and high expression of VEGF and CXCR4 was confirmed by multivariate analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195208.RAULzsXolRYAhwlPhpAdR--H5puH3raU2lgjI9nEEymOY130_provenance.
NP195212.RAWD6iMJDZ2OxgXUtkNtJMIB0SHRWT9v6PzP-eRV29D8Y130_assertion description "[Our goal was to identify patients who would benefit from cetuximab-based neoadjuvant chemoradiation measuring gene expression levels of proteins involved in tumor growth [endothelial growth factor receptor (EGFR)], angiogenesis [VEGF, VEGF receptors 1 and 2 (VEGFR1, VEGFR2)], DNA repair [excision repair cross-complementing 1 (ERCC1)], and drug metabolism [thymidylate synthetase (TS)].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195212.RAWD6iMJDZ2OxgXUtkNtJMIB0SHRWT9v6PzP-eRV29D8Y130_provenance.
NP195215.RAQ9szelDDoFJ_fkXRk-2YyXlbIudSZZK3tgpBVAXSqto130_assertion description "[In an extended family (Italy-6) of 46 members with clinical phenotypes of gestational diabetes, MODY, and T2D, a single nucleotide change of CCT to ACT was identified at codon 33 resulting in a Pro to Thr substitution (P33T) in the IPF1 transactivation domain that also contributes to an altered metabolic status in the unaffected NM subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195215.RAQ9szelDDoFJ_fkXRk-2YyXlbIudSZZK3tgpBVAXSqto130_provenance.
NP195216.RAazbfqgJHY6BNtw5ds4tK-mLj0934dCrxvyIKVXvOlkE130_assertion description "[These findings may have greatest significance in hormone refractory prostate cancer where the AR may be activated in a ligand-independent manner.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195216.RAazbfqgJHY6BNtw5ds4tK-mLj0934dCrxvyIKVXvOlkE130_provenance.
NP195226.RAQV-ObWwdrdlhWu_xSuAjcgclhvphTZfzCA0f1HEC72E130_assertion description "[These growth curves constitute a model not only for primary, hereditary insulin-like growth factor-I (IGF-I) deficiency (Laron syndrome) but also for untreated secondary IGF-I deficiencies such as growth hormone gene deletion and idiopathic congenital isolated growth hormone deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195226.RAQV-ObWwdrdlhWu_xSuAjcgclhvphTZfzCA0f1HEC72E130_provenance.
NP195228.RAfOZcmlGIK6b8YcaQOkhWu46yd1c7UuLcrG7HgVtyG_A130_assertion description "[Although the APC/beta-catenin pathway is known to play a crucial role in sporadic colorectal carcinogenesis, its influence on ulcerative colitis (UC)-related neoplastic progression is unknown.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195228.RAfOZcmlGIK6b8YcaQOkhWu46yd1c7UuLcrG7HgVtyG_A130_provenance.
NP195231.RAXvFsyqq4xqfJpqm_J5jqHBHsE78GKkX0-f6TCZwXIrw130_assertion description "[Nonchimeric polytransgenic 152F7 mice encompassing four human chromosome 21 genes (DSCR3, DSCR5, TTC3, and DYRK1A) within the Down syndrome critical region present with learning and memory impairment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195231.RAXvFsyqq4xqfJpqm_J5jqHBHsE78GKkX0-f6TCZwXIrw130_provenance.
NP195240.RAbS142xK_BEJdagPxmZZ5XWW_QWH7JnWvCB9jKX7lNnE130_assertion description "[Our study presents gene expression profiles in MM cell lines and shows the involvement of several genes, such as those encoding JAGGED1, ser/thr protein kinase NIK, Ku80 and cyclin D2, novel in MM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195240.RAbS142xK_BEJdagPxmZZ5XWW_QWH7JnWvCB9jKX7lNnE130_provenance.
NP195245.RAX2RQ3YzLrbLRUc8nXJlewKots_35Hyk1LF7Gxw1pNIg130_assertion description "[To analyze whether YB-1 expression correlates with melanoma progression in vitro and in vivo, we performed expression analysis on melanoma cell lines representing different stages of melanoma progression and on tissues of melanocytic nevi, primary melanoma and melanoma metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195245.RAX2RQ3YzLrbLRUc8nXJlewKots_35Hyk1LF7Gxw1pNIg130_provenance.
NP195248.RActy_Ju96PfTKIu_1jz8V2hxQnrNQkc5es7yFTPJJufQ130_assertion description "[A genetic marker at the glucokinase gene locus for type 2 (non-insulin-dependent) diabetes mellitus in Mauritian Creoles.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195248.RActy_Ju96PfTKIu_1jz8V2hxQnrNQkc5es7yFTPJJufQ130_provenance.
NP195251.RATorUR-1KtwZPSvNwfiltYhtlqUd-KPqbyhqT1obmpXw130_assertion description "[Wilms' tumor is a renal neoplasia commonly occurring in children and is associated with mutations of the WT1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195251.RATorUR-1KtwZPSvNwfiltYhtlqUd-KPqbyhqT1obmpXw130_provenance.
NP195257.RAS95SFhH6kGN7Cd7VnIDgI6WGtE5C0qYMENVOOWBgUkM130_assertion description "[Upon antigen binding, the intracellular signaling domains of the CAR initiate cellular activation mechanisms including cytokine secretion and cytolysis of the antigen-positive target cell.In this chapter, we provide detailed protocols for large-scale ex vivo expansion of T cells and manufacturing of medium-scale batches of CAR-expressing T cells for translational research by mRNA electroporation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195257.RAS95SFhH6kGN7Cd7VnIDgI6WGtE5C0qYMENVOOWBgUkM130_provenance.
NP195261.RAVHW8hh7eIZFDHR-z6sCW8KjPQ5hJtb7o9QMy_cqE6s4130_assertion description "[Mutations affecting either the PH, SH3, SH2 or kinase domain of BTK all give rise to X linked agammaglobulinaemia (XLA) in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195261.RAVHW8hh7eIZFDHR-z6sCW8KjPQ5hJtb7o9QMy_cqE6s4130_provenance.
NP195264.RAaE0PEQxZn-fOQb1_plsIfETpX_o7j2mZJ4z7lj9NBtg130_assertion description "[Thus far Brugada syndrome has been linked only to mutations in SCN5A, the gene encoding the alpha-subunit of cardiac Na+ channel.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195264.RAaE0PEQxZn-fOQb1_plsIfETpX_o7j2mZJ4z7lj9NBtg130_provenance.
NP195269.RAQxF_q0fAFdXAYvMwb-bM9s_wFn_QFoczIshsP5VATms130_assertion description "[In the present study, we conducted an immunohistochemical evaluation of PLAG1 and a reverse transcription-polymerase chain reaction (RT-PCR) assay to detect fusion gene transcripts associated with pleomorphic adenoma, including the CTNNB1-PLAG1, LIFR-PLAG1, CHCHD7-PLAG1, TCEA1-PLAG1, HMGA2-FHIT, HMGA2-NFIB, and HMGA2-WIF1 fusion transcripts; this was performed using formalin-fixed paraffin-embedded tumor tissue specimens of 16 cutaneous mixed tumors including one sample with an adenocarcinoma component.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195269.RAQxF_q0fAFdXAYvMwb-bM9s_wFn_QFoczIshsP5VATms130_provenance.
NP195270.RAYtmrAP_FHwRPUPQDWzi5d3iCbDl6iqOhSD9Dapgmd18130_assertion description "[These four cases and both of the HIV-1-related non-Hodgkin's lymphomas expressed the full spectrum of latent EBV gene products (LMP-1, EBER1/2, EBNA-1, EBNA-2) and were thus classified as latency type III stages of EBV infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195270.RAYtmrAP_FHwRPUPQDWzi5d3iCbDl6iqOhSD9Dapgmd18130_provenance.
NP195280.RASM57PVIg9Ew_wVLHehjhVqNOOjkY_Q0AJGkxpTq8p14130_assertion description "[To explore potential gene-gene interactions among candidate genes for ADHD, we studied the dopamine D2 receptor (DRD2), dopamine D4 receptor (DRD4), dopamine transporter (DAT1), and catechol-O-methyltransferase (COMT) genes in the Han Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195280.RASM57PVIg9Ew_wVLHehjhVqNOOjkY_Q0AJGkxpTq8p14130_provenance.
NP195281.RAc2gWzINpPkqRbpxmWavbvT87HcLOMzPeeqcti9COdaE130_assertion description "[The porin proteins PIA and PIB of Neisseria gonorrhoeae are serotyping antigens for the serovar classification system and leading candidates for gonococcal vaccine development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195281.RAc2gWzINpPkqRbpxmWavbvT87HcLOMzPeeqcti9COdaE130_provenance.
NP195285.RAeQBf7eQ_fL2j6cf6Po-CE_NFZ-zKJ6NSmDAJrtChsJQ130_assertion description "[Investigation of CD28 gene polymorphisms in patients with sporadic breast cancer in a Chinese Han population in Northeast China.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195285.RAeQBf7eQ_fL2j6cf6Po-CE_NFZ-zKJ6NSmDAJrtChsJQ130_provenance.
NP195296.RAU-aSZtYPcNr-EGItOQ_xg1wbQjTO0XHFI6zGTLtlxlE130_assertion description "[Cross-drug resistance in multidrug-resistant (MDR) cells, which overexpress P-glycoprotein (P-gp) encoded by the MDR1 gene, is a major impediment to successful chemotherapy for colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195296.RAU-aSZtYPcNr-EGItOQ_xg1wbQjTO0XHFI6zGTLtlxlE130_provenance.
NP195301.RAYDC6N0mnkPbo_zi3g9qK83HZLHpKi9vl5aeRzS5XKpI130_assertion description "[Multivariate analysis was performed, and hazard ratios (HR) calculated for variables including female gender, 3' APC mutation, surgical intervention for FAP (colectomy with ileo-rectal anastomosis or restorative proctocolectomy), age at surgery and family history (FH) of desmoids.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195301.RAYDC6N0mnkPbo_zi3g9qK83HZLHpKi9vl5aeRzS5XKpI130_provenance.
NP195302.RAaPmPaluEBEpdT_SGC6-P3yVBAIWwySqcykdyGkDEMO4130_assertion description "[By use of a Langendorff preparation, hearts from transgenic mice showed improved recovery of contractile performance during reperfusion after ischemia in an HO-1 dose-dependent manner.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195302.RAaPmPaluEBEpdT_SGC6-P3yVBAIWwySqcykdyGkDEMO4130_provenance.
NP195304.RAS-HSuPtlKxRQMHXACa85_0yuu9fLxANNVWdU-5inGgU130_assertion description "[Given that regional chromosome 13q12-q14 loss is a causal genomic event in HCC tumourigenesis, our finding may have implications for identifying a novel TSG CRYL1 within this important locus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195304.RAS-HSuPtlKxRQMHXACa85_0yuu9fLxANNVWdU-5inGgU130_provenance.
NP195311.RAU7xcz96-04QprVB3oGYFNzTe0JCVKJehdreyHrJr2PY130_assertion description "[Two groups have recently isolated cDNAs possibly encoding this enzyme, by expression cloning of human melanoma libraries in COS cells expressing the substrate ganglioside GD3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195311.RAU7xcz96-04QprVB3oGYFNzTe0JCVKJehdreyHrJr2PY130_provenance.
NP195315.RAUJYRJ3tKF1YSkfyO7AcA0bBrdfd8LckK2nDckg1pibw130_assertion description "[Several atypical forms of late infantile NCL (LINCL) have also been described including a Finnish variant LINCL (CLN5).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195315.RAUJYRJ3tKF1YSkfyO7AcA0bBrdfd8LckK2nDckg1pibw130_provenance.
NP195319.RATr26I8nQSC5htFqWeU6LTyjtrLNf3EBsIjdNhjcpXAw130_assertion description "[Finally, we show by immunohistochemistry (IHC) that RelA/p65 is abundantly expressed in malignant cells that aberrantly express hTREX84 indicating that RelA/p65 might play a pivotal role in regulating hTREX84 expression in cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195319.RATr26I8nQSC5htFqWeU6LTyjtrLNf3EBsIjdNhjcpXAw130_provenance.
NP195327.RARM-Fbn0mjaoNEYNR57VUKrRlCli_8lhD5py5mU8Wn9U130_assertion description "[The present study shows differences in the HDAC1 and HDAC2 expression in endometrial stromal sarcomas (ESS) and a cognate cell line (ESS-1) compared with nonneoplastic endometrial stroma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195327.RARM-Fbn0mjaoNEYNR57VUKrRlCli_8lhD5py5mU8Wn9U130_provenance.
NP195330.RAS-mUbGzrmLsgPA2otnYELODxwETLScUKGEuDOAIbCBg130_assertion description "[Our findings do not support the hypothesis that mutations in the HOXA11/HOXD11 coding regions are involved in the pathogenesis of human non-syndromal congenital renal parenchymal malformations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195330.RAS-mUbGzrmLsgPA2otnYELODxwETLScUKGEuDOAIbCBg130_provenance.
NP195333.RAbN1CvqxESffHe_MYRtpqsDhH9VDFjr9Pgco8AQ5D_NI130_assertion description "[MDR-1 expression and deletions of chromosomes 7 and 5(Q) separately indicate adverse prognosis in AML.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195333.RAbN1CvqxESffHe_MYRtpqsDhH9VDFjr9Pgco8AQ5D_NI130_provenance.
NP195334.RARk_K-3i0bBCzEB7DCpqqgASE9FUtKgZpTKh0b4frMvU130_assertion description "[HLA B27 was present in 20 individuals (52.6%), including those with definite and possible AS and the case with asymptomatic sacroiliitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195334.RARk_K-3i0bBCzEB7DCpqqgASE9FUtKgZpTKh0b4frMvU130_provenance.
NP195335.RAbD-69HDPu841JTuY9Nwsdhaxzd_AppPw54J8-RWBGVY130_assertion description "[Some CYP1A1/GSTM1 0/0 genotype combinations seem to predispose the lung, esophagus, and oral cavity of smokers to an even higher risk for cancer or DNA damage, requiring, however, confirmation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195335.RAbD-69HDPu841JTuY9Nwsdhaxzd_AppPw54J8-RWBGVY130_provenance.
NP195336.RAWy7FWPe4J2T43NJsbAV0AlUIjkGVlAyS8qFpYE4ELC8130_assertion description "[Genetic and developmental disruption of surfactant protein B (SP-B) expression causes neonatal respiratory distress syndrome (RDS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195336.RAWy7FWPe4J2T43NJsbAV0AlUIjkGVlAyS8qFpYE4ELC8130_provenance.
NP195337.RAX4ZPi3PhlARyOsvQzYN75eFS8JZdZC5FJ_SlQVxikbc130_assertion description "[Our results strongly suggest that the previously reported expansion of the CD5(+)CD19(+) population might be related to an expansion of the CD27(+)CD43(+) B cell subset and that CD27(+)CD43(+) B cell reconstitution is impaired in patients with chronic GVHD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195337.RAX4ZPi3PhlARyOsvQzYN75eFS8JZdZC5FJ_SlQVxikbc130_provenance.
NP195345.RAayPjZvoxHPKnF2WfS4HdpoIjBrzDHlBUMkHxat8do_Y130_assertion description "[The adipose tissue releases not only fatty acids but also a number of proinflammatory cytokines, which increase insulin resistance and cause endothelial dysfunction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195345.RAayPjZvoxHPKnF2WfS4HdpoIjBrzDHlBUMkHxat8do_Y130_provenance.
NP195350.RAU-LPIj5mXUO9zAs0XenyVCtCCR8r8TzbAgYFVcI9Ojk130_assertion description "[Thymidylate synthase and hypoxia inducible factor-1α play a central role in the control of tumor progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195350.RAU-LPIj5mXUO9zAs0XenyVCtCCR8r8TzbAgYFVcI9Ojk130_provenance.
NP195352.RAQAXjGZBXy7DvfmBhqGvGh9yGvfBxjMJeiX-A_u5IpPo130_assertion description "[Four genetic loci (FHL1, 2, 3, and 4) have been identified, of which FHL2 involves mutations in the perforin gene and is present in 20-50% of patients with FHL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195352.RAQAXjGZBXy7DvfmBhqGvGh9yGvfBxjMJeiX-A_u5IpPo130_provenance.
NP195364.RAWdOJDCnTZI5QRhPaLwFj-KhI13UlIjkO_R8tMqI7_0Y130_assertion description "[We now demonstrate the mechanisms by which AR regulates colon cancer metastasis in vitro and in vivo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195364.RAWdOJDCnTZI5QRhPaLwFj-KhI13UlIjkO_R8tMqI7_0Y130_provenance.
NP195365.RAYYRhWgnja7DKbi5Eh6CLgcG6-z2qOKdH18sX5yamH-o130_assertion description "[First description of ABCB4 gene deletions in familial low phospholipid-associated cholelithiasis and oral contraceptives-induced cholestasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195365.RAYYRhWgnja7DKbi5Eh6CLgcG6-z2qOKdH18sX5yamH-o130_provenance.
NP195366.RASDua515rtywQuaK2RatPBoIAOZv7N11s1DyGTHlx-38130_assertion description "[However, an increased expression of ENG and FLT1 was detected by qRT-PCR in the PE + SGA group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195366.RASDua515rtywQuaK2RatPBoIAOZv7N11s1DyGTHlx-38130_provenance.
NP195370.RAYYdnJW9Q9EY5afxDlX6AKwRMc1P7LbFubIAM4UB-tbM130_assertion description "[Thus, a cascade of signaling events appears to mediate the toxicity of atRAL in light-induced photoreceptor degeneration of Abca4(-/-)Rdh8(-/-) mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195370.RAYYdnJW9Q9EY5afxDlX6AKwRMc1P7LbFubIAM4UB-tbM130_provenance.
NP195376.RAQiER6RaIHpcFFBdv4rZnpnEDAZIED9x_oFIQjhoOIQc130_assertion description "[Several studies have suggested the association between CC16 and mental disturbances, such as schizophrenia, depression, and post-traumatic stress disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195376.RAQiER6RaIHpcFFBdv4rZnpnEDAZIED9x_oFIQjhoOIQc130_provenance.
NP195377.RAW1ZcOMqg6Xib0yOtkTdSt_NCSPvuBXDYWlNkKS-yrx8130_assertion description "[Despite routine bacterial screening with a bacterial culturing system (BacT/ALERT, bioMerieux) of platelet (PLT) concentrates, two cases of life-threatening sepsis attributed to transfused PLT products contaminated with Bacillus cereus were reported to the regional hemovigilance office in the southwest region of the Netherlands.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195377.RAW1ZcOMqg6Xib0yOtkTdSt_NCSPvuBXDYWlNkKS-yrx8130_provenance.
NP195384.RARClZ9-kvmoIIZsBbpPDnU21Gp-IKYh5fiin45ld2jkA130_assertion description "[Here we describe the case of a 38-year-old male presenting with ataxia, cognitive impairment and seizures, who was found to carry 43 repeats on one allele of the TATA-binding protein (TBP) gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195384.RARClZ9-kvmoIIZsBbpPDnU21Gp-IKYh5fiin45ld2jkA130_provenance.
NP195385.RAbRaXTuIYSMTo6gGbYSXj8mryEcogACmD2c2Hs-rk8U4130_assertion description "[Here, we show that, in African Americans, focal segmental glomerulosclerosis (FSGS) and hypertension-attributed end-stage kidney disease (H-ESKD) are associated with two independent sequence variants in the APOL1 gene on chromosome 22 {FSGS odds ratio = 10.5 [95% confidence interval (CI) 6.0 to 18.4]; H-ESKD odds ratio = 7.3 (95% CI 5.6 to 9.5)}.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195385.RAbRaXTuIYSMTo6gGbYSXj8mryEcogACmD2c2Hs-rk8U4130_provenance.
NP195390.RAbEnP4fFbXxSSzdRsfMXi04_d2oImlXTo_A6V9MlvgEE130_assertion description "[Familial hypercholesterolemia (FH) is a genetic disorder mainly caused by defects in the low-density lipoprotein receptor (LDLR) gene, although it can also be due to alterations in the gene encoding apolipoprotein B (familial defective apoB or FDB) or in other unidentified genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195390.RAbEnP4fFbXxSSzdRsfMXi04_d2oImlXTo_A6V9MlvgEE130_provenance.
NP195401.RAZHDVDI4ey6dR_t8JlLQEc5-Qr12FQGAIvYuIa2jnOhE130_assertion description "[The photopic, cone-derived ERG to both short- and long-duration flashes was more informative in making distinctions between these 4 disorders and understanding the possible mechanisms behind the abnormal ERG.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195401.RAZHDVDI4ey6dR_t8JlLQEc5-Qr12FQGAIvYuIa2jnOhE130_provenance.
NP195405.RAan_fQLUxtUsdzYUSrDfPDXqbEQX-ltHT6Px9WEcL8zE130_assertion description "[It is likely that vascular endothelial growth factor, pro-inflammatory cytokines, advanced glycation end products, and adhesion molecules that also play a role in diabetic retinopathy may do so by modulating the activities of aldose reductase and nitric oxide synthase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195405.RAan_fQLUxtUsdzYUSrDfPDXqbEQX-ltHT6Px9WEcL8zE130_provenance.
NP195411.RAaLue7rFfuztvW6XdYEc73pTw5j9ohI1_X1MqO__V4oE130_assertion description "[The diabetes-associated expression signature identified multiple perturbations in pathways controlling cellular metabolism and survival, including endoplasmic reticulum and oxidative stress (e.g., induction of HIF1A, DDIT3, DDIT4, and GRP78).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195411.RAaLue7rFfuztvW6XdYEc73pTw5j9ohI1_X1MqO__V4oE130_provenance.
NP195417.RAUUErrl-9Yq4DnaRWACZ1Oa6-D0PDRMxKT99bnZpFaIU130_assertion description "[Early steps in DNA damage dependent activation of the pathway are governed by monoubiquitylation of FANCD2 and FANCI by the intrinsic FA E3 ubiquitin ligase, FANCL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195417.RAUUErrl-9Yq4DnaRWACZ1Oa6-D0PDRMxKT99bnZpFaIU130_provenance.
NP195420.RAS3UbltoCWdejb8fMNLcUbJtbo5DfhZZl4cRJt5Kmd1g130_assertion description "[In this regard, candidate breast cancer TSPs include promoters of the genes for the epithelial glycoprotein 2 (EGP-2), cyclooxygenase-2 (Cox-2), alpha-chemokine SDF-1 receptor (stromal-cell-derived factor, CXCR4), secretory leukoprotease inhibitor (SLPI) and survivin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195420.RAS3UbltoCWdejb8fMNLcUbJtbo5DfhZZl4cRJt5Kmd1g130_provenance.
NP195426.RAZgKzg0506NajjTYENleFwIitbMknReEZ_35Fr856liM130_assertion description "[t(9;11)(p22;q24) in a patient with acute monocytic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195426.RAZgKzg0506NajjTYENleFwIitbMknReEZ_35Fr856liM130_provenance.
NP195437.RARY37VRBIooWjx5YQCjI-PkZrq_Rv2_MNqzKG-6kDSO4130_assertion description "[Previous studies have shown associations between KIR genes, their ligands and either protection or susceptibility to leukemias or virally associated solid tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195437.RARY37VRBIooWjx5YQCjI-PkZrq_Rv2_MNqzKG-6kDSO4130_provenance.
NP195439.RATK6U3kxUqtcc-YF7k9BicSYyTAit1s9hTHc8JdIWOQc130_assertion description "[In this study, we demonstrate that matrix metalloproteinase-1 (MMP-1), a collagenase expressed in atherosclerosis and aneurysms but not in the normal vessel wall, is induced in the aortic endothelium of rabbits exposed to cigarette smoke.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195439.RATK6U3kxUqtcc-YF7k9BicSYyTAit1s9hTHc8JdIWOQc130_provenance.
NP195442.RAS1EZnjpMqIf1635q7A8OWvlOZtIute3_9DmpuHBnv18130_assertion description "[The glutathione S-transferase (GST) enzymes inactivate a number of chemotherapeutic drugs administered in childhood ALL therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195442.RAS1EZnjpMqIf1635q7A8OWvlOZtIute3_9DmpuHBnv18130_provenance.
NP195445.RAWucqu4kL_MccdeL30gHUdgmzscvdFpuwgN46Y-PmSUc130_assertion description "[Significant differences between NOS1 genotypes were also observed among patients homozygous for the cystic fibrosis transmembrane regulator delta F508 mutation for FENO (2.3 +/- 0.4 ppb versus 5.3 +/- 0.7 ppb, p = 0.0006), and this was also true for colonization of the airways with P. aeruginosa (p = 0.0147) and Aspergillus fumigatus (p = 0.0221).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195445.RAWucqu4kL_MccdeL30gHUdgmzscvdFpuwgN46Y-PmSUc130_provenance.
NP195453.RAdfF1mNWc1CVfTCC7WeC3v9RvoNsvRXJ3HDjs0Z-Aoms130_assertion description "[The effect of IP-10 expression was shown to be dependent on IFN-gamma, as there was no statistically significant reduction in BAL eosinophilia in IFN-gamma knockout mice subjected to the IP-10 intervention.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195453.RAdfF1mNWc1CVfTCC7WeC3v9RvoNsvRXJ3HDjs0Z-Aoms130_provenance.
NP195454.RAd93I0dW9oE8Zmfqpr0agDyQRZca3EacAlxuAkLc47-M130_assertion description "[Compared to his parents who carried a single mutation in either MITF or PAX3, this child showed increased penetrance of pigmentary defects including white forelock, white eyebrows and eyelashes, and patchy facial depigmentation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195454.RAd93I0dW9oE8Zmfqpr0agDyQRZca3EacAlxuAkLc47-M130_provenance.
NP195455.RAa2jSqiCXTXGJMKlq1Tiz_nBVZ8_Sx_NEFshtD3z9JB4130_assertion description "[To determine the cross-signaling between Ca2+ and cAMP pathways, the phosphorylation of Ser16-PLB and Thr17-PLB was studied at increasing stimulation frequencies as well as in the presence of beta-adrenergic stimulation in isolated ventricular trabeculae from failing (dilative cardiomyopathy, DCM, heart transplants, n=9) and non-failing human myocardium (donor hearts, NF, n=9).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195455.RAa2jSqiCXTXGJMKlq1Tiz_nBVZ8_Sx_NEFshtD3z9JB4130_provenance.
NP195460.RAWptKr4jaXuBbui-TerhrJCCeHWdhi9UJ_r88YYqg84k130_assertion description "[This cleavage generates alpha-secretase-cleaved, soluble APP (alpha-sAPP), which in this investigation was measured by a new assay in cerebrospinal fluid (CSF) from members of a Swedish AD family with a pathogenic mutation at APP670/671 (ref.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195460.RAWptKr4jaXuBbui-TerhrJCCeHWdhi9UJ_r88YYqg84k130_provenance.
NP195461.RAV6SwxVTcleqguq0njJy9gD6qn1u95YUbvbRGJ5f2Ejk130_assertion description "[This observation emphasizes the requirement of CD40 mutation analysis for definite diagnosis of HIGM3 despite normal flow cytometric expression of CD40, particularly if the immunological and clinical profile is suggestive for HIGM3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195461.RAV6SwxVTcleqguq0njJy9gD6qn1u95YUbvbRGJ5f2Ejk130_provenance.
NP195465.RAYAWs2eGsGS9FcoCtlxcU0tO0Y7Ie3Yw3dqGXVfETTuw130_assertion description "[RET/PTC rearrangements presented at younger age and had predominantly typical papillary histology, frequent psammoma bodies, and a high rate of lymph node metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195465.RAYAWs2eGsGS9FcoCtlxcU0tO0Y7Ie3Yw3dqGXVfETTuw130_provenance.
NP195469.RAXVo86KplCJzwBSL1-7H9IJFCT5fniqp8eV31f7zkMEM130_assertion description "[Seven patients with the rare lobular breast cancer showed reduced frequency for NAT2 mutations (p < 0.05) and all of them had the extensive acetylator genotype (p < 0.01).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195469.RAXVo86KplCJzwBSL1-7H9IJFCT5fniqp8eV31f7zkMEM130_provenance.
NP195471.RAZ3B6-NZE0K1KcoERfAl95QkCbjxYmpFZJvEUBVfBEZc130_assertion description "[The hypermethylation of CDH-1 and the expression of bcl-2, cyclin D1, and beta-catenin proteins differ among breast cancer subtypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195471.RAZ3B6-NZE0K1KcoERfAl95QkCbjxYmpFZJvEUBVfBEZc130_provenance.
NP195472.RAYoksh0k4Fk3Nuyf2otN9xE85WbbvOvWR0Q0-cqcawHM130_assertion description "[This study evaluated 34 formalin-fixed, paraffin-embedded ovarian epithelial tumors for LOH by polymerase chain reaction (PCR) for the following microsatellite markers: TP53(17p13.1/p53 gene), D17S579(17q/BRCA1 gene), and ESR (6q24-27/estrogen receptor gene).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195472.RAYoksh0k4Fk3Nuyf2otN9xE85WbbvOvWR0Q0-cqcawHM130_provenance.
NP195480.RAaKq9GXkze2IECps89n8Xm15Yv4r5bzbcbcPzId9jJUg130_assertion description "[There was evidence for an aggregation of Dupuytren's disease in PDB families (not associated with SQSTM1/p62 mutation), and for an association between PDB and tobacco use.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195480.RAaKq9GXkze2IECps89n8Xm15Yv4r5bzbcbcPzId9jJUg130_provenance.
NP195482.RAVta8VyBNUFjkFDnxc57d212Nh2hpEYtrr9Bf8xt3vOU130_assertion description "[The combined assessment of the PCNA immunoreactivity and of the nuclear DNA content in routinely processed surgical specimens of breast cancer patients appears to be of prognostic value.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195482.RAVta8VyBNUFjkFDnxc57d212Nh2hpEYtrr9Bf8xt3vOU130_provenance.
NP195484.RAc4-WxGmU-SRzgvIqoWDQ2QeNGvy0DiUtPBPy-KV5nq4130_assertion description "[Immunohistochemically, the expression of eNOS and estrogen receptor alpha (ERalpha) in the vascular wall of hypertensive and OVX rats was decreased; angiotensin II and the nicotinamide adenine dinucleotide phosphate oxidase subunits nicotinamide adenine dinucleotide phosphate oxidase 4 and p22phox were strongly expressed in cerebral aneurysms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195484.RAc4-WxGmU-SRzgvIqoWDQ2QeNGvy0DiUtPBPy-KV5nq4130_provenance.
NP195485.RAcBTWtotNL05X-iE8k4sCvEqQWYGYryinxw87gce5b3s130_assertion description "[It seems that the IGF-I-IGFBP-3 combination has a longer half-life in patients with GHIS than unbound IGF-I, with fewer reports of adverse events (including hypoglycaemia) when administered to patients with diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195485.RAcBTWtotNL05X-iE8k4sCvEqQWYGYryinxw87gce5b3s130_provenance.
NP195487.RARSXbImD-VtZSDunVokjdH1wLoEglaOjf1meZwY4qG-M130_assertion description "[The contribution of prolactin (PRL) to the pathogenesis and progression of human breast cancer at the cellular, transgenic, and epidemiological levels is increasingly appreciated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195487.RARSXbImD-VtZSDunVokjdH1wLoEglaOjf1meZwY4qG-M130_provenance.
NP195491.RATpg1-Ei2xLzaZxk-Sz0vh3FtIwrZznIZJbuWrTz3stc130_assertion description "[Dysfunction of ATP7B, a copper-transporting ATPase leads to the development of Wilson's disease, i.e., multiple abnormalities in copper metabolism associated with reduced synthesis of holoceruloplasmin and biliary copper excretion controlled by both proteins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195491.RATpg1-Ei2xLzaZxk-Sz0vh3FtIwrZznIZJbuWrTz3stc130_provenance.
NP195498.RAWSXZT-MdKHpEOwEUyEJLV4D9f4Zd4Cvgo2bMUTL8szU130_assertion description "[In this context, we reveal that the knockdown of myocardin--a pivotal transcriptional determinant of the contractile SMC phenotype--is sufficient to induce SMC proliferation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195498.RAWSXZT-MdKHpEOwEUyEJLV4D9f4Zd4Cvgo2bMUTL8szU130_provenance.
NP195507.RAX-U44pBhuG4mMEgxtKvJwrEUOp7N0Ba3yDxaOvqz1dY130_assertion description "[This study is the first to report that the possible mechanism of AR inactivation in endometrial cancer is through hypermethylation of the AR gene CpG islands.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195507.RAX-U44pBhuG4mMEgxtKvJwrEUOp7N0Ba3yDxaOvqz1dY130_provenance.
NP195517.RAW0FkPl4SLHen4-_bNfFUz5qI1w5xuIh65tO2Pdt6Gs4130_assertion description "[In this study, we sought to characterize ROS1 fusion genes in non-small cell lung cancer (NSCLC) and establish the fusion proteins as drug targets.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195517.RAW0FkPl4SLHen4-_bNfFUz5qI1w5xuIh65tO2Pdt6Gs4130_provenance.
NP195524.RAWWtGsP5tTfKkMEzcoLkx3tJ-uI-9ZCREZ0SDv1NoGtE130_assertion description "[ACE 10/10 mice had increased numbers of tumor epitope-specific CD8(+) T cells after challenge with melanoma or lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195524.RAWWtGsP5tTfKkMEzcoLkx3tJ-uI-9ZCREZ0SDv1NoGtE130_provenance.
NP195527.RAe7uqI72XJVwPGzYmOAMoGx34lDCFOWxmMq8JBXZddRs130_assertion description "[MUC7 expression was highly significant for adenocarcinoma (P=0.007) and borderline for IPMN (P=0.05).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP195527.RAe7uqI72XJVwPGzYmOAMoGx34lDCFOWxmMq8JBXZddRs130_provenance.

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