Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Increase+of+LV+myocardial+mass+turned+out+age+of+patients%2C+level+of+systolic+arterial+pressure%2C+presence+of+excessive+body+mass+and+carriage+of+Arg%2FArg+genotype+of+polymorphic+marker+Gly389Arg+of+ADRB1+gene. assertion.
- assertion asSentence The+Arg389Gly+Arg%2FArg+genotype+carriers+are+associated+with+an+elevated+risk+of+essential+hypertension. assertion.
- assertion asSentence Agonist-induced+desensitization+of+cardiac+beta2ARs+is+more+pronounced+in+wild+type+than+Thr164Ile+polymorphism+subjects. assertion.
- assertion asSentence The+Arg%2816%29+and+Gln%2827%29+variants+of+the+beta%282%29-adrenergic+receptor+gene+contribute+to+metabolic+syndrome+susceptibility+in+men. assertion.
- assertion asSentence beta2-adrenoceptor+%28beta3-AR%29does+not+regulate+the+activity+of+cystic+fibrosis+transmembrane+conductance+regulator+%28CFTR%29+chloride+channel. assertion.
- assertion asSentence Genetic+variation+of+the+ADRB2+does+not+influence+the+immediate+response+to+inhaled+beta2-agonist. assertion.
- assertion asSentence Beta%282%29AR-mediated+NOS-3+activation+in+HUVEC+is+mediated+through+phosphorylation+of+NOS-3+on+serine-1177+through+both+the+PKA+and+the+PI3K%2FAkt+systems. assertion.
- assertion asSentence The+Gly16+allele+of+the+beta2-adrenoceptor+polymorphisms+links+to+weight+gain-induced+BP+elevation+associated+with+leptin+resistance. assertion.
- assertion asSentence Bronchodilator+response+in+COPD+is+associated+with+ADRB2+polymorphisms. assertion.
- assertion asSentence The+presence+of+the+Arg64+polymorphisms+of+the+ADRB3+genes+are+not+directly+related+to+indices+of+the+metabolic+syndrome+in+blach+South+African+women. assertion.
- assertion asSentence The+TACC+haplotype+of+the+ADRB2+gene+is+associated+with+an+increased+risk+of+transient+tachypnea+of+the+newborn. assertion.
- assertion asSentence High+job+stress+and+polymorphism+of+beta2-AR-16+have+an+interactive+effect+on+the+prevalence+of+hypertension+in+Chinese+male+workerss. assertion.
- assertion asSentence ADRB2+variants+are+not+associated+with+juvenile+idiopathic+arthritis+or+any+of+its+major+subtypes. assertion.
- assertion asSentence ADRB2+Arg16Gly+polymorphism+does+not+alter+lung+function+responses+to+salmeterol+or+fluticcasone+in+asthma+patienets. assertion.
- assertion asSentence The+beta2-adrenoceptor+isoleucine164+variant+is+associated+with+lower+cyclic+adenosine+monophosphate+responses+to+beta2-adrenoceptor+agonists. assertion.
- assertion asSentence Interaction+of+pVHL+with+beta%282%29AR+is+dependent+on+proline+hydroxylation+%28proline-382+and+-395%29+and+the+dioxygenase+EGLN3+interacts+directly+with+the+beta%282%29AR+to+serve+as+an+endogenous+beta%282%29AR+prolyl+hydroxylase. assertion.
- assertion asSentence For+asthma%2C+ADRB2+polymorphisms+are+not+aetiologically+involved. assertion.
- assertion asSentence The+influence+of+beta%282%29-adrenergic+receptor+%28ADRB2%29+polymorphism+on+human+physiological+function+and+in+turn+on+athletic+performance. assertion.
- assertion asSentence Genetic+polymorphisms+of+the+beta2-adrenergic+receptor+relate+to+guanosine+protein-coupled+stimulator+receptor+dysfunction+in+fibromyalgia+syndrome. assertion.
- assertion asSentence ADRB2-associated+single+nucleotide+polymorphisms+%28SNPs%29associate+with+nondipping+blood+pressure+patterns. assertion.
- assertion asSentence Confocal+imaging+of+the+Epac-based+probe+is+a+powerful+tool+to+explore+beta+2-adrenoceptor+signaling+kinetics+in+airway+smooth+muscle+cells. assertion.
- assertion asSentence Arg16Gly+ADRB2+gene+polymorphism+in+Japanese+patients+with+AERD+is+different+from+that+in+the+patients+with+ATA. assertion.
- assertion asSentence Beta%282%29AR+agonists+selectively+inhibit+the+migration+of+HASM+cells+via+a+beta%282%29AR%2FPKA%2FVASP+signaling+pathway. assertion.
- assertion asSentence An+association+between+a+genetic+variant+in+the+beta2-adrenoceptor+and+increased+susceptibility+to+bacterial+meningitis. assertion.
- assertion asSentence A+variant+in+ADRB3+influences+diabetes+risk+in+an+Mexican+American+family+and+supports+a+role+for+alterations+of+the+beta3-adrenergic+receptor+in+the+pathogenesis+of+type+2+diabetes. assertion.
- assertion asSentence Bladder+relaxation+in+man+is+mediated+exclusively+via+beta%283%29-AR. assertion.
- assertion asSentence beta3-AR+gene+Trp64Arg+polymorphism+and+ACE+gene+I%2FD+polymorphism+are+related+to+insulin+resistance+in+small+for+gestational+age+infants. assertion.
- assertion asSentence The+Arg64+allele+of+the+ADRB3+gene+in+the+ethnic+Kyrgyz+population+has+an+association+with+metabolic+syndrome+components+such+as+obesity%2C+abdominal+obesity+and+decreased+HDL-C+level. assertion.
- assertion asSentence Heterozygous+variant+of+Ser49Gly+of+ADRBK1+can+be+considered+as+one+of+genetic+predictors+of+development+of+how+primary+and+secondary+AF. assertion.
- assertion asSentence Desensitization+of+the+dopamine+D1-D2+receptor+heteromer-mediated+signal+can+occur+by+agonist+occupancy+even+without+activation+and+is+dually+regulated+by+both+the+catalytic+and+RGS+domains+of+GRK2. assertion.
- assertion asSentence Apoptosis+and+myocardial+ischemia%2Freperfusion+injury+are+found+to+be+dependent+on+level+of+G+protein-coupled+receptor+kinase-2. assertion.
- assertion asSentence No+support+for+a+major+role+for+GRK3+gene+promoter+variants+in+cocaine+addiction. assertion.
- assertion asSentence Mutation+of+a+nuclear+respiratory+factor+2+binding+site+in+the+5%27+untranslated+region+of+the+ADSL+gene+in+three+patients+with+adenylosuccinate+lyase+deficiency. assertion.
- assertion asSentence AP2alpha+negatively+regulates+HIV-1+replication+in+the+process+of+nuclear+translocation+of+viral+DNA+in+the+cytoplasm+or+the+perinuclear+region. assertion.
- assertion asSentence AFG3L1+is+a+mitochondrial+ATP-dependent+zinc+metalloprotease+transcribed+into+four+mRNA+isoforms+that+apparently+are+not+translated+in+humans. assertion.
- assertion asSentence All-trans-retinoic-acid+resistance+of+hepatoma+Bel+7402+cells+is+at+least+in+part+attributable+to+their+high+level+of+cytoplasmic+alpha-fetoprotein. assertion.
- assertion asSentence SALL4+is+a+more+sensitive+marker+than+PLAP%2C+AFP%2C+or+glypican-3+for+extragonadal+yolk+sac+tumors. assertion.
- assertion asSentence Serum+levels+of+the+onco-fetal+protein+gamma+glutamyl+transpeptidase+represent+a+useful+prognostic+parameter+in+hepatocellular+carcinoma+patients+with+low+AFP+levels. assertion.
- assertion asSentence Measurement+of+serum+AFP+at+11-13+weeks+improves+the+prediction+of+early+preterm+delivery. assertion.
- assertion asSentence Molecular+mechanism+for+the+autoproteolytic+activation+of+aspartylglucosaminidase. assertion.
- assertion asSentence Confocal+immunostaining+demonstrated+colocalization+of+m-calpain+and+the+aggrecan+product+within+the+lower+hypertrophic+chondrocytes+and+in+limited+region+of+the+pericellular+matrix. assertion.
- assertion asSentence The+RAGE+pathway+plays+a+critical+proinflammatory+role+in+vasculitic+neuropathy. assertion.
- assertion asSentence Serum+levels+are+associated+with+the+severity+of+nephropathy+in+type+2+diabetic+patients. assertion.
- assertion asSentence Treating+type+2+diabetic+patients+with+thiazolidinedione+can+increase+circulating+levels+of+RAGE. assertion.
- assertion asSentence Circulating+soluble+receptor+for+advanced+glycation+end+products+is+inversely+associated+with+body+mass+index+and+waist%2Fhip+ratio+in+the+general+population. assertion.
- assertion asSentence Structural+basis+for+pattern+recognition+by+the+receptor+for+advanced+glycation+end+products+%28RAGE%29. assertion.
- assertion asSentence Negative+RAGE+expression+correlates+with+deeper+tumor+invasion+and+venous+invasion+in+patients+with+esophageal+squamous+cell+carcinoma. assertion.
- assertion asSentence Elevated+serum+advanced+glycation+end+products+and+their+circulating+receptors+are+associated+with+anaemia+in+older+community-dwelling+women. assertion.
- assertion asSentence Stimulation+with+advanced+glycation+end+products+up-regulated+endothelial+RAGE+expression+in+saphenous+vein+endothelial+cells+cultured+from+diabetic+patients. assertion.
- assertion asSentence Plasma+levels+of+soluble+receptor+for+advanced+glycation+end+products+are+associated+with+endothelial+function+and+predict+cardiovascular+events+in+nondiabetic+patients. assertion.
- assertion asSentence Extracellular+domain+of+RAGE+down-regulates+RAGE+expression+and+inhibits+p65+and+p52+activation+in+human-salivary+gland-cell-lines. assertion.
- assertion asSentence RAGE+signaling+in+microglia+contributes+to+the+pathogenesis+of+an+inflammatory+response+that+ultimately+impairs+neuronal+function+and+directly+affects+amyloid+accumulation. assertion.
- assertion asSentence The+63+bp+del-%2F%2B+genotype+of+the+RAGE+gene+has+a+marginal+benefit+on+the+cardiovascular+event-free+survival+in+subjects+with+diabetic+nephropathy. assertion.
- assertion asSentence Role+of+RAGE+in+thromboxane+biosynthesis+in+rheumatoid+arthritis. assertion.
- assertion asSentence Both+low+serum+sRAGE+levels+and+high+AGE%2FsRAGE+ratio+have+predictive+value+for+post-percutansous+coronary+intervention+restenosis. assertion.
- assertion asSentence The+plasma+level+of+endogenous+secretory+receptor+for+advanced+glycation+end+products+is+correlated+with+higher+plasma+IL-6+and+lower+plasma+IL-1RA. assertion.
- assertion asSentence RAGE+polymorphism+is+associated+with+aspergillosis+in+stem+cell+transplant+recipients. assertion.
- assertion asSentence RAGE+polymorphisms+are+associated+with+susceptibility+to+systemic+lupus+erythematosus+%28SLE%29+and+lupus+nephritis+%28LN%29. assertion.
- assertion asSentence Mutations+associated+with+GSD+III+include+R34X+and+Y1148X. assertion.
- assertion asSentence Mutations+in+the+carbohydrate-binding+domain+of+AGL+lead+to+loss+of+all+enzymatic+activities+and+enhancing+targeting+for+proteasomal+degradation. assertion.
- assertion asSentence Single-nucleotide+polymorphisms+found+in+anorexia+nervosa. assertion.
- assertion asSentence Agouti-related+protein+is+neatively+correlated+with+nonalcolic+fatty+liver+disease+in+obese+adolescents. assertion.
- assertion asSentence Induced+an+attenuation+of+cell+motility+which+is+accompanied+by+a+decrease+in+actin+stress+fibers+and+an+increase+in+adherence+junctions+and+induces+a+NIH+3T3+cell+tranformed+phenotype+mediated+by+FGF+signaling. assertion.
- assertion asSentence Down-regulation+of+Notch-1%2C+Delta-like-1%2C+or+Jagged-1+by+RNA+interference+induces+apoptosis+and+inhibits+proliferation+in+multiple+glioma+cell+lines. assertion.
- assertion asSentence Two+mutations+in+the+NOTCH1+found+in+patients+with+left+ventricular+outflow+tract+defects+reduce+JAGGED1+induced+signaling. assertion.
- assertion asSentence A+single%2C+evolutionary+conserved+exon+defines+an+autonomous+structural+unit+that%2C+despite+the+minimal+structural+context%2C+closely+matches+the+structure+of+the+same+region+in+the+entire+receptor+binding+module. assertion.
- assertion asSentence Decreased+jagged1+expression+is+associated+with+hepatocellular+carcinoma. assertion.
- assertion asSentence Polymorphisms+of+genes+encoding+angiotensinogen+as+risk+factors+for+orthostatic+hypotension. assertion.
- assertion asSentence Maternal+and+fetal+angiotensinogen+Thr235+genotypes+are+associated+with+an+increased+risk+of+intra-uterine+growth+retardation. assertion.
- assertion asSentence Relationship+of+angiotensinogen+single+nucleotide+polymorphisms+with+elevated+blood+pressure+and+risk+of+cardiovascular+disease. assertion.
- assertion asSentence M235T+and+A%28-20%29C+genotype+of+angiotensinogen+can+influence+therapeutic+efficacy+of+renin-angiotensin+system+blockade+on+renal+survival+in+IgA+nephropathy. assertion.
- assertion asSentence ANG+II%2C+via+AT%281%29R%2C+modulates+the+secretion+of+TNF-alpha+and+MMP-2+from+vascular+endothelial+cellsANG+II%2C+via+AT%281%29R%2C+modulates+the+secretion+of+TNF-alpha+and+MMP-2+from+endothelial+cells+and+TNF-alpha+mediates+the+effects+of+ANG+II+on+MMP-2+release. assertion.
- assertion asSentence Significant+association+of+AGT+M235T+with+blood+pressure+and+cholesterol+metabolism+in+an+Afro-Caribbean+population+in+%22genetic+context%22+of+RH+blood+group+system. assertion.
- assertion asSentence Relationship+of+single-nucleotide+polymorphisms+of+the+angiotensinogen+gene+and+susceptibility+to+hypertension. assertion.
- assertion asSentence Localization+of+expression+in+the+nucleus+of+human+astrocytes+of+CCF-STTG1+line. assertion.
- assertion asSentence AGT+M235T+TT+genotype+confers+a+significantly+decreased+risk+for+the+development+of+hypertension. assertion.
- assertion asSentence A+mutation+in+the+upstream+core+promoter+of+angiotensinogen+is+associated+with+liver+cirrhosis. assertion.
- assertion asSentence Carriage+of+AGT+single+nucleotide+polymorphism+is+associated+with+an+increased+risk+for+H.pylori-related+gastric+cancer+development+in+Japanese. assertion.
- assertion asSentence The+TT+genotype+of+AGT+M235T+is+associated+with+malignant+hypertension+in+whites%2C+carriers+having+an+odds+of+approximately+10+to+1+compared+to+hypertensive+and+normotensive+controls. assertion.
- assertion asSentence A+haplotype+of+human+angiotensinogen+gene+containing+-217A+increases+blood+pressure+in+transgenic+mice+compared+with+-217G. assertion.
- assertion asSentence Ligand-activated+PPARdelta+confers+resistance+to+Ang+II-induced+senescence+by+up-regulation+of+PTEN+and+ensuing+modulation+of+the+PI3K%2FAkt+signaling+to+reduce+ROS+generation+in+vascular+cells. assertion.
- assertion asSentence Polymorphic+variants+of+AGT+gene-M235T+and+T174M-show+association+with+hypertension. assertion.
- assertion asSentence Polymorphisms+of+genes+encoding+the+AT1+receptor+as+risk+factors+for+orthostatic+hypotension. assertion.
- assertion asSentence The+vasoconstrictively+acting+genotype+AT1R+C%2FC+is+of+similar+prevalence+in+recurrent+spontaneous+abortions+patients+and+in+controls. assertion.
- assertion asSentence ACE+I%2FD+and+AT1R+1166A%2FC+polymorphisms+affect+coronary+artery+stenosis+in+patients+with+Kawasaki+disease+%28KD%29. assertion.
- assertion asSentence Polymorphism+is+not+associated+with+increased+risk+of+developing+chronic+kidney+allograft+dysfunction. assertion.
- assertion asSentence An+imbalance+of+AT1R+and+AT2R+activity+in+mesangial+cells+following+exposure+to+pIgA+plays+a+significant+pathogenetic+role+in+the+inflammatory+injury+in+IgA+nephropathy. assertion.
- assertion asSentence Depression+patients+with+a+haplotype+combining+the+CC+and+DD%2FID+genotypes+respond+better+to+treatment+than+those+with+either+single+allele. assertion.
- assertion asSentence AT1R+genotype+is+an+independent+predictor+of+both+plasma+protein+carbonyls+and+myeloperoxidase+levels+in+heart+failure. assertion.
- assertion asSentence The+1166C+allele+in+angiotensin+II+type+1+receptor+increases+the+risk+of+CAD+associated+with+the+presence+of+cigarette+smoking+and+hypercholesterolemia. assertion.
- assertion asSentence There+is+no+relationship+between+the+A1166C+gene+polymorphism+of+AT%281R%29+gene+and+hypertension+of+Kazakh+people. assertion.
- assertion asSentence Inhibition+of+B-Raf+kinase+leads+to+a+marked+reduction+in+angiotensin+II+receptor+type+1+in+the+cerebrovasculature. assertion.
- assertion asSentence The+beta-arrestin+pathway-selective+type+1A+angiotensin+receptor+%28AT1A%29+agonist+%5BSar1%2CIle4%2CIle8%5Dangiotensin+II+regulates+a+robust+G+protein-independent+signaling+network. assertion.
- assertion asSentence A+polymorphic+miR-155+binding+site+in+AGTR1+is+associated+with+cardiac+hypertrophy+in+Friedreich+ataxia. assertion.
- assertion asSentence TGF-beta1+downregulates+AT1+receptor+expression+via+PKC-delta-mediated+Sp1+dissociation+from+KLF4+and+Smad-mediated+PPAR-gamma+association+with+KLF4. assertion.
- assertion asSentence Angiotensin+II+receptor+type+2+signaling+can+be+manipulated+by+modifying+its+export+trafficking+along+the+secretory+pathway. assertion.
- assertion asSentence The+loss+of+AT%282%29+receptor+signalling+is+associated+with+increased+renal+injury+and+mortality+in+chronic+kidney+disease. assertion.
- assertion asSentence Angiotensin+II+receptor+type+2+receptors+are+indispensable+during+islet+-like+cell+clusters+maturation+in+vivo. assertion.
- assertion asSentence AGTRL1+polymorphism+is+not+associated+with+coronary+artery+disease. assertion.
- assertion asSentence Disruption+of+apelin-APJ+signaling+can+exacerbate+pulmonary+hypertension+mediated+by+decreased+activation+of+AMP-activated+kinase+and+eNOS. assertion.