Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Abortion+is+associated+with+increased+expression+of+FasL+in+decidual+leukocytes. assertion.
- assertion asSentence Paeoniflorin+inhibits+A549+cell+proliferation+via+Fas%2FFasL+apoptosic+pathway. assertion.
- assertion asSentence High+FASL+is+associated+with+breast+ductal+carcinoma. assertion.
- assertion asSentence Several+members+of+the+PCH+proteins+interact+with+the+proline-rich+region+of+Fas+ligand+%28FasL%2C+CD95L%29%2C+a+key+death+factor+in+immune+cells. assertion.
- assertion asSentence Polymorphisms+in+the+FASL+is+associated+with+early+stage+non-small+cell+lung+cancer. assertion.
- assertion asSentence Fas+ligand+enhances+malignant+behavior+of+tumor+cells+through+interaction+with+Met%2C+hepatocyte+growth+factor+receptor%2C+in+lipid+rafts. assertion.
- assertion asSentence Transmembrane+helices+at+the+periphery+of+the+hAQP1+tetramer+exhibited+smaller+extraction+forces+than+helices+at+the+interface+between+hAQP1+monomers. assertion.
- assertion asSentence AQP1+expression+heavely+in+cystic+hemangioblastomas. assertion.
- assertion asSentence The+expression+of+AQP1+in+tumor+cells+and+micro-angiogenesis+of+primary+laryngeal+carcinoma+are+higher+than+normal. assertion.
- assertion asSentence TXA%282%29+receptor+mediates+water+influx+through+aquaporins+in+astrocytoma+cells+via+TXA%282%29+receptor-mediated+activation+of+G+alpha%2812%2F13%29%2C+Rho+A%2C+Rho+kinase+and+Na%28%2B%29%2FH%28%2B%29-exchanger. assertion.
- assertion asSentence Compared+with+human+AQP1%2C+zebrafish+Aqp1a+has+about+twice+the+selectivity+for+CO%282%29+over+NH%283%29. assertion.
- assertion asSentence Where+renal+water+retention+is+stimulated+via+arginine+vasopressin+%28AVP%29%2C+urinary+AQP2+measurements+provide+a+reproducible+measurement+of+the+renal+actions+of+AVP. assertion.
- assertion asSentence Reduction+in+the+amounts+of+AQP-2+and+AQP-3+expression%2C+especially+in+lesions+with+substantial+interstitial+fibrosis+and+nephron+loss%2C+as+compared+with+a+healthy+region+of+normal+kidneys. assertion.
- assertion asSentence Presence+of+anti-AQP4+antibodies+correlates+with+clinical+severity+and+poor+prognosis+in+opticospinal+multiple+sclerosis. assertion.
- assertion asSentence Anti-AQP4+antibody-positive+patients+are+immunologically+distinct+from+anti-AQP4+antibody-negative+opticospinal+multiple+sclerosis+patients. assertion.
- assertion asSentence The+gene+expressions+of+AQP3+and+AQP4+in+gastric+mucosa+are+different+in+patients+with+various+degrees+of+spleen-stomach+dampness-heat+syndrome+of+chronic+superficial+gastritis. assertion.
- assertion asSentence Aquaporin+9+is+linked+to+the+tumorigenesis+of+glioblastoma. assertion.
- assertion asSentence The+aggregation+and+localization+of+the+truncated+form%2C+with+or+without+an+expanded+polyglutamine+tract%2C+is+differentially+controlled+by+Glucocorticoid+receptor+mutants. assertion.
- assertion asSentence SWI%2FSNF+function+potently+regulates+core+AR+target+gene+promoter+activation%2C+with+a+preference+for+hBRM-containing+complexes. assertion.
- assertion asSentence There+is+a+direct+interaction+between+the+AR+DNA+binding+domain+%28DBD%29+and+Tcf4. assertion.
- assertion asSentence The+repeat+polymorphisms+in+the+AR+gene+are+associated+with+bone+mass+in+women+with+high+levels+of+sex-hormone+binding+globulin. assertion.
- assertion asSentence Promoter+methylation+of+AR+occurs+in+a+differentiation+stage-selective+manner+in+follicular+non-hodgkin%27s+lymphoma. assertion.
- assertion asSentence Androgen+receptor+CAG+repeat+polymorphism+is+associated+with+cognitive+function+in+older+men. assertion.
- assertion asSentence Interactions+between+AR+and+beta-catenin+contribute+to+prostate+cell+growth+in+vivo. assertion.
- assertion asSentence AR+and+estrogen+receptor+beta+are+important+in+relatively+early+coronary+atherosclerosis. assertion.
- assertion asSentence 4-estren-3alpha17beta-diol+binds+recombinant+AR+with+10-fold+higher+affinity+than+either+estrogen+receptor+%28ER%29-alpha+or+ERbeta. assertion.
- assertion asSentence Androgen+receptor+%28AR%29+CAG+repeat+not+associated+with+migraine+susceptibility. assertion.
- assertion asSentence Androgen+receptor+is+recruited+to+the+promoter+of+the+c-FLIP+gene+in+the+presence+of+androgens. assertion.
- assertion asSentence The+distal+enhancer+complex+and+basal+transcription+apparatus+of+Fkbp5+gene+communicate+indirectly+with+one+another%2C+implicating+a+regulatory+mechanism+that+has+not+been+previously+appreciated+for+androgen+receptor+target+genes. assertion.
- assertion asSentence SMRT+and+N-CoR+corepressors+are+involved+in+transcriptional+regulation+by+both+agonist-+and+antagonist-bound+AR+and+regulate+the+magnitude+of+hormone+response%2C+at+least+in+part%2C+by+competing+with+coactivators. assertion.
- assertion asSentence Androgen+and+androgen+receptor+promote+Bax-mediated+apoptosis+in+prostate+cancer+cells. assertion.
- assertion asSentence AR-AF1+domain+exhibits+induced+folding+when+contacted+by+transcription+regulators+%28such+as+TFIIF%29+into+a+more+compact+and+%27active%27+conformation. assertion.
- assertion asSentence Distribution+of+polymorphisms+in+SRD5A2+and+androgen+receptor+differed+between+prostate+cancer+low-risk+population+from+Greenland+and+relatively+high-risk+Swedish+male+population. assertion.
- assertion asSentence ErbB-2%2C+via+PYK2-MAP+kinase%2C+upregulates+the+adhesive+ability+of+androgen+receptor+human+prostate+cancer+cells. assertion.
- assertion asSentence Inappropriate+activation+of+androgen+receptor+by+relaxin+via+beta-catenin+pathway. assertion.
- assertion asSentence Association+of+androgen+receptor+trinucleotide+repeats+with+hormone+refractory+prostatic+cancer+patients+in+a+north+Indian+population. assertion.
- assertion asSentence GnRH+II+is+widely+expressed+in+prostate+cancer+and+is+an+AR-regulated+gene. assertion.
- assertion asSentence The+PCR+HUMARA+technique+adequately+assesses+reduction+of+Ph-positive+clone+in+CML+patients+with+CCR+and+points+to+polyclonal+hemopoiesis. assertion.
- assertion asSentence The+time-dependent+EGF-induced+increase+in+AR+transcriptional+activity+by+MAGE-11+is+mediated+through+AR+activation+functions+1+and+2+in+association+with+the+increased+turnover+of+AR+and+MAGE-11. assertion.
- assertion asSentence An+association+between+AR+trinucleotide+repeats+and+prostate+cancer+risk+in+a+population-based+sample+of+African+Americans. assertion.
- assertion asSentence Calcitriol+requires+a+functional+AR+to+inhibit+the+expression+of+the+UGT2B17+gene+in+LNCaP+cells. assertion.
- assertion asSentence UGT2B15+and+B17+are+primary+androgen-regulated+genes+and+androgen+receptor+is+required+for+both+their+basal+expression+and+their+androgen-regulated+expression. assertion.
- assertion asSentence The+androgen+receptor+gene+and+EDA2R+are+significantly+associated+with+androgenetic+alopecia. assertion.
- assertion asSentence TRIM68+regulates+ligand-dependent+transcription+of+androgen+receptor+in+prostate+cancer+cells. assertion.
- assertion asSentence AR+genes+are+overexpressed+by+granulosa+cells+from+stimulated+follicles+of+women+with+polycystic+ovary+syndrome+undergoing+controlled+ovarian+hyperstimulation. assertion.
- assertion asSentence There+is+an+association+of+androgen+receptor+CAG+repeat+polymorphism+length+with+obesity+and+serum+leptin+in+men+with+type+2+diabetes. assertion.
- assertion asSentence The+AR+CAG+repeat+length+correlates+significantly+with+serum+T+and+estradiol+of+aging+men. assertion.
- assertion asSentence SENP1+reverses+the+ligand-induced+SUMOylation+of+AR+and+helps+fine+tune+the+cellular+responses+to+androgens+in+a+target+promoter-selective+manner. assertion.
- assertion asSentence The+AR+mutations+at+residue+754+and+690+bound+androgen+with+decreasing+affinity. assertion.
- assertion asSentence Secreted+Frizzled-related+protein-1+is+a+negative+regulator+of+androgen+receptor+activity+in+prostate+cancer. assertion.
- assertion asSentence Polyglutamine-expanded+AR+must+reside+within+nuclei+in+the+presence+of+its+ligand+to+cause+spinal+and+bulbar+muscular+atrophy. assertion.
- assertion asSentence Treatment+with+antiandrogens+selects+for+gain-of-function+AR+mutations+with+altered+stability+in+treatment+of+prostate+cancer. assertion.
- assertion asSentence Aryl+hydrocarbon+receptor+%28AhR%29+modulation+of+androgen+receptor+activity+is+differentially+altered+by+the+level+of+FHL2+and+AhR+present+in+the+cell. assertion.
- assertion asSentence N-terminal+domain+of+AR+interacts+with+PPARGC1a+to+enhance+DNA-binding+of+AR+to+androgen-responsive+elements+in+prostate-specific+enhancer+and+promoter+regions+to+increase+transcription+of+AR+target+genes. assertion.
- assertion asSentence Boundaries+within+AR+and+CYP19A1+that+are+associated+with+endometrial+cancer+risk. assertion.
- assertion asSentence AR+expression+is+an+independent+prognostic+factor+of+better+outcome+in+patients+with+estrogen+receptor-positive+breast+cancers. assertion.
- assertion asSentence HP1beta+is+involved+in+the+proliferation+of+AR-expressing+prostate+cancer+cells+and+progression+to+CRPC+as+an+AR+coactivator. assertion.
- assertion asSentence Androgen+receptor+polymorphism+is+linked+to+genetic+susceptibility+to+urinary+incontinence. assertion.
- assertion asSentence Hematopoietic+differentiation+is+permissive+to+the+reversal+of+methylation+status+of+HUMARA+in+some+terminally+differentiated+progenitors. assertion.
- assertion asSentence TSPY+serves+as+a+repressor+in+androgen-induced+tumor+development+in+testicular+germ-cell+tumors. assertion.
- assertion asSentence Low+EGFR+expression+is+associated+with+triple-negative+breast+cancer. assertion.
- assertion asSentence AR+is+significantly+associated+with+favorable+features+in+breast+cancers+and+related+to+better+outcomes+in+estrogen+receptor+%28ER%29-positive+not+in+ER-negative+tumors. assertion.
- assertion asSentence Low+AR+gene+expression+is+associated+with+treatment+response+in+breast+cancer. assertion.
- assertion asSentence The+CAG+repeat+polymorphism+in+the+androgen+receptor+gene+is+important+in+explaining+a+broad+range+of+individual+differences+in+human+males. assertion.
- assertion asSentence Conditional+activation+of+transgenic+AR+expression+by+Osr1+promoter+induces+prostate+tumor+formation+in+mice. assertion.
- assertion asSentence AR+polyglutamine+repeat+length+is+directly+associated+with+transcriptional+activity+and+alters+the+growth+and+development+of+C2C12+cells. assertion.
- assertion asSentence Reduced+CAG+repeat+length+is+a+risk+factor+for+prostate+cancer+in+Nigerians. assertion.
- assertion asSentence 0.5+muM+CTS+effectively+suppresses+the+growth+of+AR-positive+PCa+cells. assertion.
- assertion asSentence %28TARP%29+expression+in+prostate+cancer+cells+leads+to+an+increased+growth+rate+and+induction+of+caveolins+and+amphiregulin. assertion.
- assertion asSentence MIP-3alpha-mediated+ERK1%2F2+activation+in+Caco-2+cells+appeared+to+require+metalloproteinase-dependent+release+of+the+endogenous+EGFR+ligand+amphiregulin+and+transactivation+of+the+EGFR. assertion.
- assertion asSentence Amphiregulin+has+a+protective+effect+against+apoptosis+in+the+human+corpus+luteum. assertion.
- assertion asSentence AREG+accumulation+is+a+useful+marker+of+gonadotrophin+stimulation+and+oocyte+competence. assertion.
- assertion asSentence Lung+tumor-associated+dendritic+cell-derived+amphiregulin+increased+cancer+progression. assertion.
- assertion asSentence Overexpression+of+SPN+causes+activation+of+the+tumor+suppressor+protein+ARF1. assertion.
- assertion asSentence N376+to+D+mutation+in+the+conserved+NPxxY+motif+within+the+carboxy+terminal+tail+domain+%28CT%29+of+the+5-HT2A+receptor+alters+the+binding+preference+of+GST-fusion+protein+constructs+of+the+CT+domain+from+ARF1+to+an+alternative+isoform%2C+ARF6. assertion.
- assertion asSentence Molecular+basis+of+phosphatidylinositol+4-phosphate+and+ARF1+GTPase+recognition+by+the+FAPP1+pleckstrin+homology+%28PH%29+domain. assertion.
- assertion asSentence The+lipid+droplets+deposition+and+the+cellular+triacylglycerol+content+are+significantly+increased+by+siRNA-mediated+depletion+of+Arf5. assertion.
- assertion asSentence ARNO+and+ARF6+coordinate+with+the+Dock180%2FElmo+complex+to+promote+Rac+activation+at+the+leading+edge+of+migrating+cells. assertion.
- assertion asSentence Arf6+regulates+both+endocytosis+and+recycling+of+beta1+integrins+and+BRAG2+functions+selectively+to+activate+Arf6+during+integrin+internalization. assertion.
- assertion asSentence ACAP4+is+involved+in+ARF6-mediated+cell+migration. assertion.
- assertion asSentence SCAMP2+regulates+NHE5+transit+through+recycling+endosomes+and+promotes+its+surface+targeting+in+an+Arf6-dependent+manner. assertion.
- assertion asSentence EGF-induced+ARF6+expression+plays+a+significant+role+in+glioma+cell+proliferation. assertion.
- assertion asSentence GEP100+functions+in+phagocytosis+via+its+role+in+ARF6-dependent+actin+remodeling. assertion.
- assertion asSentence CNK3+and+IPCEF1+produce+a+single+protein+that+is+required+for+HGF+dependent+Arf6+activation+and+migration. assertion.
- assertion asSentence GEP100%2FArf6+is+required+for+epidermal+growth+factor-induced+ERK%2FRac1+signaling+and+cell+migration+in+human+hepatoma+HepG2+cells. assertion.
- assertion asSentence Loss+of+arginase+is+associated+with+allergic+pulmonary+inflammation. assertion.
- assertion asSentence High+arginase+1+is+associated+with+rheumatoid+arthritis. assertion.
- assertion asSentence RhoA+activation+plays+an+integral+role+in+tissue+factor+expression+in+endothelial+cells. assertion.
- assertion asSentence Activation+of+Rho+GTPases+and+coordinated+rearrangement+of+F-actin+within+uterine+epithelial+cells+in+response+to+trophoblast+binding+are+part+of+a+generalized+structural+and+functional+reorganization+of+the+cytoplasm. assertion.
- assertion asSentence GIT1+redistribution+occurs+independently+of+Rac+and+requires+RhoA+and+Rho+kinase. assertion.
- assertion asSentence GTPase+RhoA+and+atypical+protein+kinase+Czeta+are+required+for+TLR2-mediated+gene+transcription. assertion.
- assertion asSentence In+intact+cells%2C+GrinchGEF+induced+specifically+Rho+activation+and+enhanced+RhoA-C-specific+downstream+effects. assertion.
- assertion asSentence HEF1+associates+with+the+RhoA-GTP+exchange+factor+ECT2%2C+an+orthologue+of+the+Drosophila+cytokinetic+regulator+Pebble%2C+providing+a+direct+means+for+HEF1+control+of+RhoA. assertion.
- assertion asSentence Escherichia+coli+producing+cytotoxic+necrotizing+factor+and+transforming+growth+factor-beta+trigger+activated+RhoA+ubiquitylation+through+Smurf1+ubiquitin-ligase. assertion.
- assertion asSentence PTP1B+mediates+of+RhoA-dependent+phosphorylation+of+p130Cas. assertion.
- assertion asSentence ARAP2+is+an+Arf6GAP+that+functions+downstream+of+RhoA+to+regulate+focal+adhesion+dynamics. assertion.
- assertion asSentence Expression+level+of+RhoA+is+correlated+with+tumor+progression+and+metastasis+in+hepatocellular+carcinoma. assertion.
- assertion asSentence OLIG2+suppresses+the+motile+phenotype+of+glioblastoma+cells+by+activating+RhoA. assertion.
- assertion asSentence p27+promotes+cell+migration+in+metastatic+HCC+cells+through+the+regulation+of+RhoA+activity. assertion.
- assertion asSentence ET-1+induces+Rho-kinase+activation+and+subsequent+phosphorylation+of+p190A+RhoGAP%2C+leading+to+prolonged+RhoA+activation. assertion.