Nanopublications LDF server

Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }

• NP45536.RAtNl5o5GDr0XP0FWwZXakKi4yuMJ0Dwi3sDVzntcYbCI130_assertion description "[Polymorphisms 3020insC in CARD15 and SNP rs3792876 in SLC22A4/5 occurred statistically significantly more often in patients with pediatric-onset CD than in patients with adult-onset CD. Polymorphisms 3020insC in CARD15 and SNP rs2165047 in DLG5 were associated with specific phenotypes in this pediatric-onset CD cohort.(Inflamm Bowel Dis 2007).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45536.RAtNl5o5GDr0XP0FWwZXakKi4yuMJ0Dwi3sDVzntcYbCI130_provenance.
• NP45540.RAkQ3SRdRTSpRSo9ipkbwQQX6nKEXaGcIrf10jjoSbeR8130_assertion description "[The DLD genotype appears to operate independently of APOE in conferring AD risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45540.RAkQ3SRdRTSpRSo9ipkbwQQX6nKEXaGcIrf10jjoSbeR8130_provenance.
• NP45543.RAojT-ujROpDpWEs0iCSzXd1_yABSi87ftJ_AKZRsoA7A130_assertion description "[Our data suggest complex epistatic effects implicating an NRG1 molecular pathway in cognitive brain function and the pathogenesis of schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45543.RAojT-ujROpDpWEs0iCSzXd1_yABSi87ftJ_AKZRsoA7A130_provenance.
• NP45550.RAj-d-4HilPMnrL-qjw8eRxX3KHvERIebkM2FouyZiC8g130_assertion description "[Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45550.RAj-d-4HilPMnrL-qjw8eRxX3KHvERIebkM2FouyZiC8g130_provenance.
• NP45555.RAqf65apYHTH-vNntggkHd41hy98eKEoOUeGfesCNGpAE130_assertion description "[Positive association of the DIO2 (deiodinase type 2) gene with mental retardation in the iodine-deficient areas of China.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45555.RAqf65apYHTH-vNntggkHd41hy98eKEoOUeGfesCNGpAE130_provenance.
• NP45561.RAjAvvD2VVUvALXTLHa1ROjnhISsZuW330gmfwzKy07Z4130_assertion description "[Smith-Lemli-Opitz syndrome is caused by mutations in the Delta7 sterol-reductase gene (DHCR7; EC 1.3.1.21), which impair endogenous cholesterol biosynthesis and make the growing embryo dependent on exogenous (maternal) sources of cholesterol.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45561.RAjAvvD2VVUvALXTLHa1ROjnhISsZuW330gmfwzKy07Z4130_provenance.
• NP45562.RAi0000UP_FCatT159vmYCC_Qkda9qWpa6LD3tJXinXyw130_assertion description "[The calculated carrier frequency for all mutations based on this result is 1 in 30, predicting an SLOS incidence of 1 in 1590 to 1 in 13,500. The current incidence estimate may, therefore, significantly underestimate the true incidence of SLOS. This discrepancy between calculated and observed incidence could be due to undiagnosed mild cases, misdiagnosed severe cases, death prior to diagnosis, or fetal loss. More comprehensive incidence studies are needed to determine if SLOS is as common as predicted by the very high (1 in 30) carrier frequency determined in this study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45562.RAi0000UP_FCatT159vmYCC_Qkda9qWpa6LD3tJXinXyw130_provenance.
• NP45563.RAgweJDaT51PHLLHT0KGDL4DAX9qC62-MFIGnkiUxrkx0130_assertion description "[Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive disorder of cholesterol biosynthesis caused by mutations in the DHCR7 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45563.RAgweJDaT51PHLLHT0KGDL4DAX9qC62-MFIGnkiUxrkx0130_provenance.
• NP45566.RAjnBbuQWOdyN682xiUjjzqBxCplfWyj3hk-mBEfclXUs130_assertion description "[ Antibodies to the 45 kDa DEK protein are characteristic of the pauciarticular onset subtype of JRA, particularly in patients with a history of iridocyclitis. The occurrence of anti-DEK antibodies is significantly but paradoxically associated with the presence of the HLA-A2 allele in such patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45566.RAjnBbuQWOdyN682xiUjjzqBxCplfWyj3hk-mBEfclXUs130_provenance.
• NP45567.RAhEGzuBt8FN5Sy8LMixotTwi45-0gFOu5jtg17Ebibqc130_assertion description "[ Variation in DEFB1 contributes to asthma diagnosis, with apparent gender-specific effects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45567.RAhEGzuBt8FN5Sy8LMixotTwi45-0gFOu5jtg17Ebibqc130_provenance.
• NP45569.RAl_9gB1DNCiPGh8l5IroE0NlwUczhyBVox1avv7iSW6g130_assertion description "[The observed haplotypic association provides the first evidence of the importance of DDAH1 polymorphisms in pre-eclampsia susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45569.RAl_9gB1DNCiPGh8l5IroE0NlwUczhyBVox1avv7iSW6g130_provenance.
• NP45570.RAlG3ZhIf8vwWm8fwmRjvX5qIec22ZWTZBqd4FIOQBWpA130_assertion description "[Dopa decarboxylase gene polymorphisms and attention deficit hyperactivity disorder (ADHD): no evidence for association in the Irish population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45570.RAlG3ZhIf8vwWm8fwmRjvX5qIec22ZWTZBqd4FIOQBWpA130_provenance.
• NP45577.RAqrEWT_BC_MpAjKQ9Kyz1hCWHWB-NWCMrTeGqnoUh2RM130_assertion description "[Since the Italian population usually shows allelic frequencies similar to the other Caucasian populations, we suggest that the T54A allele might play a role in infertility only in Taiwanese or Asiatic individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45577.RAqrEWT_BC_MpAjKQ9Kyz1hCWHWB-NWCMrTeGqnoUh2RM130_provenance.
• NP45586.RAknrMUlGHvYRDpNqV5Po4MhMqaulsci1K18VuwuHP050130_assertion description "[The present Scandinavian results do not verify previous associations between the analyzed DTNBP1, NRG1, DAO, DAOA, and GRM3 gene polymorphisms and schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45586.RAknrMUlGHvYRDpNqV5Po4MhMqaulsci1K18VuwuHP050130_provenance.
• NP45587.RAsYQ_QBvCSH-v2Ig1m8wD_xJ3NN1eAFPEwA9Z_GiocNI130_assertion description "[Association of G72/G30 polymorphisms with early-onset and male schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45587.RAsYQ_QBvCSH-v2Ig1m8wD_xJ3NN1eAFPEwA9Z_GiocNI130_provenance.
• NP45592.RAitUxiGPOVKcB5tLOoIKL9R1t_DfJu297Sng58JCWAsI130_assertion description "[In this work, we have identified statistically significant differences in allele distributions of two markers rs3916965 (P = 0.019) and rs2391191 (P = 0.0010), and a highly significant association between haplotype AGAC of the G72/G30 locus (P = 1.7 x 10(-4)) and schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45592.RAitUxiGPOVKcB5tLOoIKL9R1t_DfJu297Sng58JCWAsI130_provenance.
• NP45605.RAmY6XuYXt2UfHSmW9VmZGXthyYp3jnYZiKG3EUJQl0gg130_assertion description "[The results suggest a certain trend of associations that could help to explain some controversial results in association studies of these genes from the leukotriene pathway, when considered individually.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45605.RAmY6XuYXt2UfHSmW9VmZGXthyYp3jnYZiKG3EUJQl0gg130_provenance.
• NP45607.RAveQswfg5HkfiNmX7UsZrs_ouQk9fHtaCFwSFUjcXGcQ130_assertion description "[5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45607.RAveQswfg5HkfiNmX7UsZrs_ouQk9fHtaCFwSFUjcXGcQ130_provenance.
• NP45609.RAsZ8ItUJ160RioeXtf_IbwjSMmHEqtxx43EtJIlokfGA130_assertion description "[When we compared the allele frequencies of the CYSLTR1 SNP between asthmatics and non-asthmatics, the 927C allele was found to be a risk allele for asthma (OR=2.13, 95% CI: 1.06-4.26, p=0.033).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45609.RAsZ8ItUJ160RioeXtf_IbwjSMmHEqtxx43EtJIlokfGA130_provenance.
• NP45610.RAo0sQ27NBX9GmOUvu6lwpwwFQRhlDVra9HGPiGcdSwMA130_assertion description "[The presence of subgroups of patients that do not respond to the drug was an important reason for nonresponse.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45610.RAo0sQ27NBX9GmOUvu6lwpwwFQRhlDVra9HGPiGcdSwMA130_provenance.
• NP45616.RAttXLVQIkxBzqFM2M4qXViY480FRVESxv5_pEQrfDnUo130_assertion description "[The aim of this study was to verify the finding that CYP7A1 polymorphism may be associated with gallstone disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45616.RAttXLVQIkxBzqFM2M4qXViY480FRVESxv5_pEQrfDnUo130_provenance.
• NP45621.RAs5EOdQeO_F0VwHNj60ecfzb9UlVQ32ssODobiJmr02o130_assertion description "[Given the relatively high frequency and the functional consequences of the CYP4B1*2 allele, associations between CYP4B1 polymorphism and certain pathological processes should be considered.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45621.RAs5EOdQeO_F0VwHNj60ecfzb9UlVQ32ssODobiJmr02o130_provenance.
• NP45622.RAhHMRCLaTe3XkV8TJoRS_aqILzbAFyvPyQMsdNbBoJN8130_assertion description "[ We identified a variant of the human CYP4A11 (T8590C) that encodes for a monooxygenase with reduced 20-HETE synthase activity. The association of the T8590C variant with hypertension supports its role as a polygenic determinant of blood pressure control in humans, and results obtained from the large population database suggest that the relevance of the variant may vary according to hypertension comorbidity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45622.RAhHMRCLaTe3XkV8TJoRS_aqILzbAFyvPyQMsdNbBoJN8130_provenance.
• NP45629.RAhgmppDTvmHGvToWJbKY7yvsdbNbXaohmhe9Jis34pPY130_assertion description "[Clinical characteristics of myotonic dystrophy type 1 patients with small CTG expansions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45629.RAhgmppDTvmHGvToWJbKY7yvsdbNbXaohmhe9Jis34pPY130_provenance.
• NP45631.RAmhIS8rKMwVAZgyGF0P_IprtDskyydTvPo2P09ZiSYQ0130_assertion description "[Myotonic dystrophy type 1 (DM1) is due to an unstable expansion of CTG repeat in the DMPK gene (19q13.3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45631.RAmhIS8rKMwVAZgyGF0P_IprtDskyydTvPo2P09ZiSYQ0130_provenance.
• NP45638.RAstr8ChDJo97tYZu4WNcgPVm_i4WR3R0bRnRuNL7LAgw130_assertion description "[Recent studies have suggested that variants of CYP46A1, encoding cholesterol 24-hydroxylase (CYP46), confer risk for Alzheimer's disease (AD), a prospect substantiated by evidence of genetic association from several quantitative traits related to AD pathology, including cerebrospinal fluid (CSF) levels of the 42 amino-acid cleavage product of beta-amyloid (Abeta42) and the tau protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45638.RAstr8ChDJo97tYZu4WNcgPVm_i4WR3R0bRnRuNL7LAgw130_provenance.
• NP45650.RAhgthhrhyh8mf-1fGqI08I8tK1gD_EIelsOLAwnfypj8130_assertion description "[ These results suggest that these epoxygenase-related SNP are not associated with increased risk of hypertension in the African American population. There was significant linkage disequilibrium between CYP2C8*3 and CYP2C9*2 alleles that was not associated with hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45650.RAhgthhrhyh8mf-1fGqI08I8tK1gD_EIelsOLAwnfypj8130_provenance.
• NP45656.RAglF3FyYfxMceNZF0DVQkASJT0cj1GQIAvcwYjynxglA130_assertion description "[c2c2 homozygote of CYP2E1 PstI/RsaI polymorphism may be associated with the increased risk of colorectal cancer in Caucasians, which needs further investigations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45656.RAglF3FyYfxMceNZF0DVQkASJT0cj1GQIAvcwYjynxglA130_provenance.
• NP45657.RAnFRhKo270qM-kLE9yjAbD17CJp4DlN3f9pxvT1uDLpA130_assertion description "[The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45657.RAnFRhKo270qM-kLE9yjAbD17CJp4DlN3f9pxvT1uDLpA130_provenance.
• NP45658.RAs3cASmaZ-0U09D75Cva6LUhgK_Tg4o2t0He1bvAQ6Co130_assertion description "[Genetic polymorphisms of CYP2E1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45658.RAs3cASmaZ-0U09D75Cva6LUhgK_Tg4o2t0He1bvAQ6Co130_provenance.
• NP45659.RAohVNcLEd1l_GPyWXNIeCsi0YyywfKgGBGKhw9KhWt6k130_assertion description "[Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45659.RAohVNcLEd1l_GPyWXNIeCsi0YyywfKgGBGKhw9KhWt6k130_provenance.
• NP45661.RAiqi4S1JRq5P6kUw_Sy8iWE_Y1K_9IYwrraWqdGXM3VI130_assertion description "[Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45661.RAiqi4S1JRq5P6kUw_Sy8iWE_Y1K_9IYwrraWqdGXM3VI130_provenance.
• NP45666.RArVWdOtIko6WCpmP351is6yvoaZ1_mkq3IN3kE5vLlL4130_assertion description "[ This study has identified a number of genes requiring further investigation including EPHX1, ADPRT1, CYP2D6, and AhR.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45666.RArVWdOtIko6WCpmP351is6yvoaZ1_mkq3IN3kE5vLlL4130_provenance.
• NP45669.RAmVPMmKVp_SLIZBwKny5D5hYhinuj6zsIgDpOzFxu16s130_assertion description "[To clarify the hypothesis that genetic polymorphisms in alcohol-metabolizing enzymes may influence susceptibility to lung cancer, the authors conducted a hospital-based case-control study and examined genetic polymorphisms in the alcohol dehydrogenase 3, aldehyde dehydrogenase 2 (ALDH(2)), and cytochrome P450 2E1 genes in 505 patients with histologically confirmed lung cancer and in a group of 256 noncancer controls who provided complete cigarette and alcohol consumption histories.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45669.RAmVPMmKVp_SLIZBwKny5D5hYhinuj6zsIgDpOzFxu16s130_provenance.
• NP45671.RAikYVCY_sHqa5BADiJ6QcO9UiPNVwSAcOvVoO_WnmuSs130_assertion description "[CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45671.RAikYVCY_sHqa5BADiJ6QcO9UiPNVwSAcOvVoO_WnmuSs130_provenance.
• NP45674.RAgaBkKv6Uz998BIMk8QSkKyqvBFNh_89DP0CSznxSYzI130_assertion description "[Effect of combined genetic polymorphisms on lung cancer risk in northern Thai women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45674.RAgaBkKv6Uz998BIMk8QSkKyqvBFNh_89DP0CSznxSYzI130_provenance.
• NP45676.RAnD56MotYVpiJUU9wiDDb5sKqeNTj_nGTH-J1WU5Wc1E130_assertion description "[ The data demonstrate site-dependent associations between GSTT1 null and CYP2D6 PM and tumor extension and lymph node involvement in SCC of the head and neck.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45676.RAnD56MotYVpiJUU9wiDDb5sKqeNTj_nGTH-J1WU5Wc1E130_provenance.
• NP45677.RAlqVj81chVy-TOOclD-CNMveX3iDsAXVDmlqW_zAlqEc130_assertion description "[ Patients suffering from multiple SCC development showed a cumulation of high risk genotypes at GST and TNF gene loci. Specific genetic variations could not be determined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45677.RAlqVj81chVy-TOOclD-CNMveX3iDsAXVDmlqW_zAlqEc130_provenance.
• NP45679.RAjfbs9hZhlO9wPWAtvZIx1zjEh0ys4mbMC6FIyevyrS4130_assertion description "[Cytochrome P450 2E1 and head and neck cancer: interaction with genetic and environmental risk factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45679.RAjfbs9hZhlO9wPWAtvZIx1zjEh0ys4mbMC6FIyevyrS4130_provenance.
• NP45680.RAtm1H-7Rx2UhyYatZHhWEvOOPeLTinU2Hal7fTLLUvS8130_assertion description "[We here investigated ADH1C Ile(350)Val, ADH1B Arg(48)His, ADH1B Arg(370)Cys and CYP2E1*5A PstI polymorphisms by PCR-RFLP Polymerase Chain Reaction - Restriction Fragment Length Polymorphism in 207 histopathologically confirmed HNC cases (184 males and 23 females) and 244 cancer-free controls (225 males and 19 females) admitted as in-patients in the same hospital.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45680.RAtm1H-7Rx2UhyYatZHhWEvOOPeLTinU2Hal7fTLLUvS8130_provenance.
• NP45694.RAoiROOc5McgMWu3nh54EqxtImo8fKncVQ_6W7KFM78ss130_assertion description "[Most dietary factors and polymorphisms of GSTM1, GSTT1, CYP1A1, CYP2E1, ALDH2, and L-myc genes are not independent risk factors for gastric cancer with hypermethylation of the hMLH1 promoter.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45694.RAoiROOc5McgMWu3nh54EqxtImo8fKncVQ_6W7KFM78ss130_provenance.
• NP45701.RAvPZNKSDwosjIvFOOir2LtL7e8L6BmfgnLpU3Q_ve-is130_assertion description "[In this report, genetic polymorphism of phase I and II metabolic enzyme (CYP2E1, CYP17, GSTM1 and GSTT1) genes, living habits, and risk of prostate cancer (PCa) was studied in 163 patients with prostate carcinoma of Han nationality in Southern China and 202 age-matched controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45701.RAvPZNKSDwosjIvFOOir2LtL7e8L6BmfgnLpU3Q_ve-is130_provenance.
• NP45711.RApPSBnNBqz1gVWYjOyyy2ckrWpdPgXLkMi8VLJPNtn1o130_assertion description "[These findings suggest that combination of several polymorphisms in the enzymes that activate or detoxify the tobacco smoke, such as EPHX1 and HMOX1, might be associated with its affects on the development of emphysematous changes of the lung.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45711.RApPSBnNBqz1gVWYjOyyy2ckrWpdPgXLkMi8VLJPNtn1o130_provenance.
• NP45714.RAj8nXJOg8WrilMSjIF39snKtZ4itSd5DyNpJNyViCuX0130_assertion description "[Further studies using larger populations will be needed to confirm our observations and to validate data for disease prevention.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45714.RAj8nXJOg8WrilMSjIF39snKtZ4itSd5DyNpJNyViCuX0130_provenance.
• NP45728.RAswSsZfOYPqWGWvYd7QQwUxD45ECzmwKmOU424XbNH6g130_assertion description "[Both NSAID use and CYP2C9*2 and/ or *3 carriage are associated with a reduced risk of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45728.RAswSsZfOYPqWGWvYd7QQwUxD45ECzmwKmOU424XbNH6g130_provenance.
• NP45731.RAkRLkQj1RfemQCFBUl0Yam3Sv80bONcTIAo7z_E2PmXI130_assertion description "[Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45731.RAkRLkQj1RfemQCFBUl0Yam3Sv80bONcTIAo7z_E2PmXI130_provenance.
• NP45735.RAqrCe9thGjBNYKgj1xIi43gZYs25dLcXmuRN-EYn6BOo130_assertion description "[Combinations of cytochrome P450 gene polymorphisms enhancing the risk for sporadic colorectal cancer related to red meat consumption.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45735.RAqrCe9thGjBNYKgj1xIi43gZYs25dLcXmuRN-EYn6BOo130_provenance.
• NP45737.RAqP-Sxg4VU0iltAS-kp1fo_y3-LFbfrAXnKo9SdXBzAQ130_assertion description "[ The CYP2C9*5 allele was analysed using a polymerase chain reaction-based endonuclease method, and it was found in three Tanzanians (allele frequency, 0.0082) but not in Ethiopians, Caucasians or Orientals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45737.RAqP-Sxg4VU0iltAS-kp1fo_y3-LFbfrAXnKo9SdXBzAQ130_provenance.
• NP45746.RArLWbu2zMvbt1IOmIjcl7TRnBP-8zqZb4SO--QBB7FZM130_assertion description "[ In this investigation geriatric patients showed a high rate of ADRs. However, no association between the ADR rate and the patients' genotype could be detected, which most likely was a result of the small number of patient samples analysed.Although prophylactic genotyping would have not prevented ADRs in this pilot study, physicians nevertheless have to be aware of potential genetic mutations in patients with polypharmacy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45746.RArLWbu2zMvbt1IOmIjcl7TRnBP-8zqZb4SO--QBB7FZM130_provenance.
• NP45747.RAs_6RIIAggpNCa3_OJ0Xz-q8cLTxpjDuWqTx3Sw3RiYw130_assertion description "[ Polymorphism of the CYP2C8 gene was found to be common, with nearly 30% of the population studied carrying the variant CYP2C8*3 allele. The presence of the latter caused a significant effect on the disposition of (R)-ibuprofen. This suggests that a substantial proportion of Caucasian subjects may show alterations in the disposition of drugs that are CYP2C8 substrates.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45747.RAs_6RIIAggpNCa3_OJ0Xz-q8cLTxpjDuWqTx3Sw3RiYw130_provenance.
• NP45750.RAgQrXM74DRhdZU8dN2oW5W5KrdIPAj68WMnork85s0KI130_assertion description "[Genetic polymorphisms and lung cancer susceptibility: a review.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45750.RAgQrXM74DRhdZU8dN2oW5W5KrdIPAj68WMnork85s0KI130_provenance.
• NP45754.RAiKS2raiJWtuWmaCThM-T0Xh8uYUQImOBS97VFZTSU1k130_assertion description "[Interethnic differences were elucidated for several polymorphisms that might be responsible for differential serum drug levels and optimal dose requirement for efficacious treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45754.RAiKS2raiJWtuWmaCThM-T0Xh8uYUQImOBS97VFZTSU1k130_provenance.
• NP45758.RAh1jhvVJiPQk0dxp8Uq9J4KDHSOGRA2K1CsgS63rlZHw130_assertion description "[Genetic polymorphism in exon 4 of cytochrome P450 CYP2C9 may be associated with warfarin sensitivity in Chinese patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45758.RAh1jhvVJiPQk0dxp8Uq9J4KDHSOGRA2K1CsgS63rlZHw130_provenance.
• NP45767.RAuXBmr3_paQF7CCdaOEKNinXh6UJnSH8M7XzO8WZ67Z8130_assertion description "[In the present study, we aimed to analyze the potential relevance of the polymorphism in the promoter region of the serotonin transporter (SERT or 5-HTT) gene (5-HTTLPR) and the risk of suffering major depression (MDD) in a population of patients previously genotyped for CYP2C9.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45767.RAuXBmr3_paQF7CCdaOEKNinXh6UJnSH8M7XzO8WZ67Z8130_provenance.
• NP45771.RApOqyLHLFlWiSTBe23cQsXObM9WFZ1ApomWbXsVa3EGU130_assertion description "[The odds ratio for bleeding patients receiving CYP2C9 substrates (n=33) was 2.5 for heterozygous and 3.7 for homozygous carriers of mutations (P<0.015), suggesting that the inherited impairment of CYP2C9 activity increases the risk for severe adverse drug reactions after NSAIDs use.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45771.RApOqyLHLFlWiSTBe23cQsXObM9WFZ1ApomWbXsVa3EGU130_provenance.
• NP45773.RAh9E2vg0Oav0mB_G4o7CV1Il8cqu0qKUuTCb5BJ77Iuc130_assertion description "[ In some Caucasian populations the impact of the CYP2C9 polymorphism may be much higher than that estimated from genotyping studies published to date.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45773.RAh9E2vg0Oav0mB_G4o7CV1Il8cqu0qKUuTCb5BJ77Iuc130_provenance.
• NP45779.RAt65u-qZE7YAE2COofkY5nKWFDymobk6S1Q_rlpQRb-Y130_assertion description "[Possession of rare genetic variants of the CYP2C8 and CYP2C9 genes in females is associated with a modest increase in risk of AMI.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45779.RAt65u-qZE7YAE2COofkY5nKWFDymobk6S1Q_rlpQRb-Y130_provenance.
• NP45781.RAnCe4B1XfQ4_Z06m9v2D558_vmmm40N2JQKNnwosRmOc130_assertion description "[In conclusion, the elaborated protocol for real-time PCR analysis of gene mutations CYP2C8*2, *3, and *4 is reliable and cost effective, and thus, suitable for routine laboratory use.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45781.RAnCe4B1XfQ4_Z06m9v2D558_vmmm40N2JQKNnwosRmOc130_provenance.
• NP45783.RAg31iUaJCX9Ng-Df-HdePTAjK0KbvthN4UKZR0kic9Tk130_assertion description "[Although several SNPs such as CYP2C8*2, CYP2C8*3, CYP2C8*4, and P404A have been reported to reduce the enzymatic activity, pharmacokinetic abnormalities of drugs metabolized by polymorphic CYP2C8 might be rare in Japanese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45783.RAg31iUaJCX9Ng-Df-HdePTAjK0KbvthN4UKZR0kic9Tk130_provenance.
• NP45789.RAtfc9AOtMhuETlNhE9H4Ki7E4GkIJ8AqC1PQ-RjKmJEU130_assertion description "[Polymerase chain reaction-restriction fragment polymorphism for the identification of CYP2C8*1, CYP2C8*2, CYP2C8*3 and CYP2C8*4 on a random population of 165 unrelated malaria patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45789.RAtfc9AOtMhuETlNhE9H4Ki7E4GkIJ8AqC1PQ-RjKmJEU130_provenance.
• NP45790.RAk9NDQRlFW7cuTQg_zJF0fQx7Rd2LCvrYKQFCq0UXhF0130_assertion description "[CYP2C8 non-wild type alleles have a significant prevalence in the East African population studied. The consequent frequency of 3.6% of patients homozygous for slow metabolizer alleles represent a significant fraction of the population potentially in higher risk of adverse effects due to a less efficient metabolism of amodiaquine. As approximately 10(6) first-line treatments are currently performed in Zanzibar per year, this represents a non-negligible absolute number of amodiaquine exposures. This information constitutes a background for the pharmacovigilance programs presently being employed in Zanzibar. ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45790.RAk9NDQRlFW7cuTQg_zJF0fQx7Rd2LCvrYKQFCq0UXhF0130_provenance.
• NP45798.RAiIat28ZGeaSQr2KUY_7ipD9_19klcvXSHJNn-YeUBzY130_assertion description "[ There is no statistically significant difference in genetic mutant alleles between the two groups, except for the genotype of CYP2A6*4A homozygous. The frequency of this genotype in the HCC patients (0.144) is significantly higher than that in healthy Japanese (0.034; P < 0.05; odds ratio 3.36). The clinical significance related to HCC is unknown. Further evaluation of CYP2A6*4A (deletion type) in HCV-related HCC patients is required.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45798.RAiIat28ZGeaSQr2KUY_7ipD9_19klcvXSHJNn-YeUBzY130_provenance.
• NP45801.RAqtfC5_RGq1F9v9OswwNWke5knZSHYZZ9kt51GXV20ZQ130_assertion description "[This study highlights the medical consequences of population origins and the need for a better understanding of the genetic diversity of our global species.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45801.RAqtfC5_RGq1F9v9OswwNWke5knZSHYZZ9kt51GXV20ZQ130_provenance.
• NP45802.RAu2aVWAI5xCdtgWgVwmG-5BvbJQcxk1V73mnD1MTTt84130_assertion description "[The PM phenotype and the frequencies of CYP2C19 defective alleles in Thais, particularly CYP2C19*3, were lower than those observed in other Oriental populations. It is noteworthy that there was a case of nonaccordance between phenotype and genotype in one of the PMs. Whether this PM represents a novel defective allele requires further investigation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45802.RAu2aVWAI5xCdtgWgVwmG-5BvbJQcxk1V73mnD1MTTt84130_provenance.
• NP45803.RAubBhE36eQsX2nG_BAhq8aJZiLKU3fht2mLW6H9F3gjo130_assertion description "[the investigated cytochrome genes do not seem to play a major role in antidepressant response in the present sample of depressive patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45803.RAubBhE36eQsX2nG_BAhq8aJZiLKU3fht2mLW6H9F3gjo130_provenance.
• NP45811.RAjaNSFmbYQKCbFpxYTXcylHmGWMJrnHK7FKCwL3vnZR0130_assertion description "[Polymorphism of CYP2C19 and gastric emptying in patients with proton pump inhibitor-resistant gastric ulcers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45811.RAjaNSFmbYQKCbFpxYTXcylHmGWMJrnHK7FKCwL3vnZR0130_provenance.
• NP45812.RAvDzyPN_HG9tsr2Gsx2_8-kE3jmd7218FnlMIIrw1dKs130_assertion description "[We evaluated gastric ulcer improvement after 1 week's treatment with rabeprazole or omeprazole in relation to CYP2C19 polymorphism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45812.RAvDzyPN_HG9tsr2Gsx2_8-kE3jmd7218FnlMIIrw1dKs130_provenance.
• NP45813.RAhWU2GY59fPaSSfNSLL-wRAWoFyH7bYvBo96x--xjGro130_assertion description "[ The combination regimen of famotidine plus rabeprazole is more effective for nocturnal acid inhibition in homozygous and heterozygous EMs than the increased dosage regimen of rabeprazole. This concomitant therapy could be a rescue regimen for patients with nocturnal acid breakthrough refractory to a standard PPI therapy who are likely to be CYP2C19 EMs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45813.RAhWU2GY59fPaSSfNSLL-wRAWoFyH7bYvBo96x--xjGro130_provenance.
• NP45823.RAv7jHAfDPtUn4Vx7sbNrMqL8jtkNNcejrjf93ZMM1t54130_assertion description "[ Our results suggest that alleles at CYP loci may be involved in increasing susceptibility to scleroderma among subjects who have been exposed to organic solvents.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45823.RAv7jHAfDPtUn4Vx7sbNrMqL8jtkNNcejrjf93ZMM1t54130_provenance.
• NP45836.RAhHmOpCNS8O3UZ-wRg6RgE-p1cCVEfdOya0dNHxSsVX4130_assertion description "[Genetic polymorphisms and lung cancer susceptibility: a review.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45836.RAhHmOpCNS8O3UZ-wRg6RgE-p1cCVEfdOya0dNHxSsVX4130_provenance.
• NP45837.RAlbD5eHxzfQItL8kxEMtI5z1WnqD_WGVVhvzCQsKAeQs130_assertion description "[Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45837.RAlbD5eHxzfQItL8kxEMtI5z1WnqD_WGVVhvzCQsKAeQs130_provenance.
• NP45838.RAjRn5u5dlMz-uBab5INWr6uB8hSbWJHNPgC0lwKq69U0130_assertion description "[These results presumably suggest that the CYP2A6 is one of the principal determinants affecting not only smoking behaviors but also susceptibility to tobacco-related lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45838.RAjRn5u5dlMz-uBab5INWr6uB8hSbWJHNPgC0lwKq69U0130_provenance.
• NP45840.RAiDHT8h3NSvY1SP6YXGtmmyJj_9T26usg2agy3hHf4pw130_assertion description "[Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45840.RAiDHT8h3NSvY1SP6YXGtmmyJj_9T26usg2agy3hHf4pw130_provenance.
• NP45845.RAgYuyptH2wcFRX5wBGp6Ed5tzC_mj40qPJiiYmHu-0b8130_assertion description "[Our data suggest that deficient CYP2A6 activity due to genetic polymorphism reduces oral cancer risk in betel quid chewers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45845.RAgYuyptH2wcFRX5wBGp6Ed5tzC_mj40qPJiiYmHu-0b8130_provenance.
• NP45853.RAlCh5wtVOgkfpu2M5DkJTccTPFhA12WpRN8rqtngTR4I130_assertion description "[Congenital adrenal hyperplasia (CAH) is a common autosomal recessive disorder which causes more than 90% of CAH cases due to defects in the steroid 21-hydroxylase gene (CYP21A2).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45853.RAlCh5wtVOgkfpu2M5DkJTccTPFhA12WpRN8rqtngTR4I130_provenance.
• NP45854.RAlZEAwX06vcKL5BptHeU023fVVaLcBfyfpbuftZi0DYc130_assertion description "[The frequency of eight common point mutations in CYP21 gene in Iranian patients with congenital adrenal hyperplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45854.RAlZEAwX06vcKL5BptHeU023fVVaLcBfyfpbuftZi0DYc130_provenance.
• NP45857.RAos84JlwMPxtplwZjiD0WheVGGw4gLDMozRk9Sq7WxBQ130_assertion description "[Neonatal screening for steroid 21-hydroxylase (CYP21) deficiency is performed to identify congenital adrenal hyperplasia (CAH).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45857.RAos84JlwMPxtplwZjiD0WheVGGw4gLDMozRk9Sq7WxBQ130_provenance.
• NP45860.RAndkmgBpm2eqC3RHfNX7yAOXKeYJ7uaf8SqxwFgQ4YTc130_assertion description "[The study aimed to perform molecular characterization in 43 Romanian patients with classical CAH forms diagnosed at the Center for Genetic Diseases of the Pediatric Clinic/University Cluj (38 with 21-hydroxylase deficiency, five with 11beta-hydroxylase deficiency), to determine the frequency of mutations in the CYP21A2 gene and attempt a genotype-phenotype correlation in patients with 21-hydroxylase deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45860.RAndkmgBpm2eqC3RHfNX7yAOXKeYJ7uaf8SqxwFgQ4YTc130_provenance.
• NP45864.RAj4gV8Z1voSYZxbuUc2HOWT94RZsiHHKOaQJeflLud7U130_assertion description "[Significant differencies in selected regions were determined by ANOVA statistical analysis (One-sample t-test, confidence interval) at value of p < 0.05.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45864.RAj4gV8Z1voSYZxbuUc2HOWT94RZsiHHKOaQJeflLud7U130_provenance.
• NP45877.RAjEa-z43KWv66IjlKfvoQ2dtroMfqK3obJZTEjCfLk04130_assertion description "[ Hydrocortisone substitution in 21-hydroxylase-deficient patients should be kept at the lowest efficient level, if possible <20 during the first year and <15 mg/m2/day until age 5 and during puberty. Normal growth and not complete androgen suppression should be aimed for.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45877.RAjEa-z43KWv66IjlKfvoQ2dtroMfqK3obJZTEjCfLk04130_provenance.
• NP45881.RAmKcnxOcxKvK5TM9Q2sa9rwMIkjjkoQL6iAMXw8-iaZ0130_assertion description "[Most of the variants in the candidate breast cancer genes evaluated in this study are not strong predictors of breast density. However, our findings of differences in associations for UGT1A1 and AIB1 genotypes with breast density by menopausal status needs additional corroboration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45881.RAmKcnxOcxKvK5TM9Q2sa9rwMIkjjkoQL6iAMXw8-iaZ0130_provenance.
• NP45882.RAr7Hzmn3-sojKvXFlw5yon2FtyPbWZCAiJVox0WTz5G0130_assertion description "[Our data suggest lower mammographic density for women carrying the COMT and CYP1A2 variant alleles than for women carrying the common alleles, though this is the opposite of what is commonly hypothesized from the enzyme function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45882.RAr7Hzmn3-sojKvXFlw5yon2FtyPbWZCAiJVox0WTz5G0130_provenance.
• NP45885.RAltzyCtw7hOcvi68FDQJbympoaRK1AlI1jFj3-EuBTmU130_assertion description "[Although we found no significant association in the three populations combined, subgroup analyses revealed statistically significant associations of CYP1A2*1F in NJB, and CYP1B1 Leu(432)Val and CYP3A5*3 in JJ with breast cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45885.RAltzyCtw7hOcvi68FDQJbympoaRK1AlI1jFj3-EuBTmU130_provenance.
• NP45889.RAtAwynwknw7B-PR17TpS9MaeqBQMtL6RN4rRVvPQVuPM130_assertion description "[Four single nucleotide polymorphisms (SNPs) in CYP1B1 (Ex2 + 143 C > G, Ex2 + 356 G > T, Ex3 + 251 G > C, Ex3 + 315 A > G) cause amino acid changes (R48G, A119S, L432V and N453S, respectively) and are associated with increased formation of catechol estrogens; however, epidemiologic evidence only weakly supports an association between these variants and breast cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45889.RAtAwynwknw7B-PR17TpS9MaeqBQMtL6RN4rRVvPQVuPM130_provenance.
• NP45891.RAjO5hnVPfdrjfSFZyrIyMJiFgwSxR7KVlf_yjrevlVFI130_assertion description "[Because of the important role of cytochrome P450 1B1 ( CYP1B1) and catechol O-methyltransferase ( COMT) in mammary estrogen and carcinogen metabolism, we examined the CYP1B1 and COMT genes to determine whether genetic variations could account for inter-individual differences in breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45891.RAjO5hnVPfdrjfSFZyrIyMJiFgwSxR7KVlf_yjrevlVFI130_provenance.
• NP45893.RAlYn89FIyVOxp-BtVzn1mwk83qNJ1zT9_pyGCyOnRnkE130_assertion description "[The distribution of NAT2 activity in the healthy control group was found to be correlated with that of healthy caucasians. Patients had slow acetylator phenotypes of NAT2, 1.8 times higher than controls but no statistical differences were found (p=0.07). In addition, the NAT2*5 alelle was more statistically correlated with breast cancer patients rather than the controls (p=0.02). Moreover, NAT2*5B was the most frequent haplotype of the NAT2*5 family (p=0.000). Breast cancer patients were detected to posses more CYP1B1*3 mutant alleles than the controls (p=0.043). The combined effect of CYP1B1*3 polymorphism and NAT2 slow acetylator genotype contributed to an increased risk for breast cancer in patients in this study (p=0.004).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45893.RAlYn89FIyVOxp-BtVzn1mwk83qNJ1zT9_pyGCyOnRnkE130_provenance.
• NP45894.RAtxbbUiRUitQnqevnzLFNymOQjYTKUitOnKcXDfSVPek130_assertion description "[Associations of functional single nucleotide polymorphisms in cytochrome P450 1B1, epoxide hydrolase 1, NAD(P)H:quinone oxidoreductase 1, glutathione S-transferase Pi-1 and deletions of glutathione S-transferases Mu-1 and -1 with colorectal cancer risk were investigated in a hospital-based case-control study on 495 matched pairs of Czech Caucasians.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45894.RAtxbbUiRUitQnqevnzLFNymOQjYTKUitOnKcXDfSVPek130_provenance.
• NP45896.RAqGnuHqsP33Sdh2P3kCHL7QZpxLkBT3qbRff13NdYLVw130_assertion description "[Genetic variants within the CYP1B1 that are associated with altered function appear to influence susceptibility to a colorectal cancer in Poland. Three haplotypes were associated with altered cancer risk; one conferred protection and two were associated with an increased risk of disease. These observations should be confirmed in other populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45896.RAqGnuHqsP33Sdh2P3kCHL7QZpxLkBT3qbRff13NdYLVw130_provenance.
• NP45898.RAnt7nSshVbOmt7UTnd1AA7b0dk1igzpTi2goo5TT4pww130_assertion description "[Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45898.RAnt7nSshVbOmt7UTnd1AA7b0dk1igzpTi2goo5TT4pww130_provenance.
• NP45899.RAgbkD0cIpFG_6UsZwfRGQ_RWizFL0C2_OLVB9V33-pzQ130_assertion description "[Combinations of cytochrome P450 gene polymorphisms enhancing the risk for sporadic colorectal cancer related to red meat consumption.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45899.RAgbkD0cIpFG_6UsZwfRGQ_RWizFL0C2_OLVB9V33-pzQ130_provenance.
• NP45902.RAhwcXwMG7AeLrg4E4rBpcDiQcSvkmbwHUFOKXayNraKo130_assertion description "[In a case-control study, we investigated the genotype frequencies of 10 estrogen metabolizing SNPs in 32 patients with endometriosis and 790 healthy controls using sequencing-on-chip-technology with solid-phase polymerase chain reaction on oligonucleotide microarrays: catechol-O-methyltransferase, Val158Met G->A, 17-beta-hydroxysteroid dehydrogenase type 1 (HSD17), vlV A->C, cytochrome P450 (CYP), 17 A2 allele T->C, CYP1A1 MspI RFLP T->C, CYP1A1 Ile462Val A->G, CYP19 Arg264Cys C->T, CYP19 C1558T C->T, CYP 1B1 Leu432Val, CYP1B1 Asn453Ser, and estrogen receptor alpha IVS1 -401>C. Associations and 2-way interaction models between SNPs were calculated by stepwise logistic regression models.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45902.RAhwcXwMG7AeLrg4E4rBpcDiQcSvkmbwHUFOKXayNraKo130_provenance.
• NP45909.RAo3WJ028iufpGdp9T2Uaqaoq_Z3vquK3TnHQdfg1KiSc130_assertion description "[Among women with long-term use of estrogen replacement therapy or combined hormone replacement therapy, the risk of endometrial cancer may be associated with functionally relevant genotypes that regulate steroid hormone sulfation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45909.RAo3WJ028iufpGdp9T2Uaqaoq_Z3vquK3TnHQdfg1KiSc130_provenance.
• NP45917.RAkG4_2hd0Q5WPgbYF_O4FE5Y_SFwnAQkxm0W1skjaNXM130_assertion description "[Risk of testicular germ cell cancer in relation to variation in maternal and offspring cytochrome p450 genes involved in catechol estrogen metabolism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45917.RAkG4_2hd0Q5WPgbYF_O4FE5Y_SFwnAQkxm0W1skjaNXM130_provenance.
• NP45918.RAqB1POhg-VaUsdNwcah3NwbeHn-jhBR2hYulox9H4VF4130_assertion description "[CYP and GST polymorphisms and survival in advanced non-small cell lung cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45918.RAqB1POhg-VaUsdNwcah3NwbeHn-jhBR2hYulox9H4VF4130_provenance.
• NP45921.RAoOU_BF_0QcMubqxfcL_Fml3SsP_I9eMc-aSb0j307ac130_assertion description "[Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45921.RAoOU_BF_0QcMubqxfcL_Fml3SsP_I9eMc-aSb0j307ac130_provenance.
• NP45923.RArd8P6oSXmPVDSTMTrxtR6l315DgO04w7LfGs3UKU0HE130_assertion description "[Association of functionally important polymorphisms in cytochrome P4501B1 with lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45923.RArd8P6oSXmPVDSTMTrxtR6l315DgO04w7LfGs3UKU0HE130_provenance.
• NP45925.RAoDfXSu_YW_c4BuwXtLtiTvcY1h9ni3kcJ1kqrXX6j8k130_assertion description "[CYP1B1, CYP1A1, MPO, and GSTP1 polymorphisms and lung cancer risk in never-smoking Korean women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45925.RAoDfXSu_YW_c4BuwXtLtiTvcY1h9ni3kcJ1kqrXX6j8k130_provenance.
• NP45926.RAiS2IOmZjb8D0OAR8oD47ZmY6YcLx3dE1InXTDfBQ5p4130_assertion description "[Combinations of cytochrome P-450 genotypes and risk of early-onset lung cancer in Caucasians and African Americans: a population-based study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45926.RAiS2IOmZjb8D0OAR8oD47ZmY6YcLx3dE1InXTDfBQ5p4130_provenance.
• NP45939.RAjKPevzUkm47whIavhdN3D_NTTu4cAxzBo-n5RrQtULM130_assertion description "[This study was conducted to investigate the mutation spectrum of the cytochrome P450 gene (CYP1B1) in Chinese patients with primary congenital glaucoma (PCG).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45939.RAjKPevzUkm47whIavhdN3D_NTTu4cAxzBo-n5RrQtULM130_provenance.
• NP45941.RApO1TZT_1fXq5vZntkF43cGcGvbOax6r09P1tfjUXcHM130_assertion description "[Our results indicate that only a minor proportion of German PCG patients harbor mutations in the CYP1B1 gene and are in line with similar studies from other ethnic populations in which the rate of consanguinity is low.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP45941.RApO1TZT_1fXq5vZntkF43cGcGvbOax6r09P1tfjUXcHM130_provenance.

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