Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP46411.RAgLzGkYfNm5HzO6OrQ0Urm4lPGFrQiVHmsBPB8_GL-MM130_assertion description "[CT60 single nucleotide polymorphism of the CTLA-4 gene is associated with susceptibility to Graves' disease in the Taiwanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46411.RAgLzGkYfNm5HzO6OrQ0Urm4lPGFrQiVHmsBPB8_GL-MM130_provenance.
- NP46414.RAo5AfUAvcY9k0TWtk6-W3PGsMC-is2dFsrE4Jp0kX10k130_assertion description "[We performed a case control study on 150 patients with GD and 301 controls, matched for age and gender, to verify the association of three polymorphisms located in CTLA-4 region (A49G, AT(n)-3'UTR, and CT60) and of HLA-DRB1 and DQB1 loci with the disease in an Italian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46414.RAo5AfUAvcY9k0TWtk6-W3PGsMC-is2dFsrE4Jp0kX10k130_provenance.
- NP46419.RAjZCyTaqHdRzjnxehduL7GOUk4uUHi5XGdK98ShoQpIM130_assertion description "[The APOE locus and the pharmacogenetics of lipid response.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46419.RAjZCyTaqHdRzjnxehduL7GOUk4uUHi5XGdK98ShoQpIM130_provenance.
- NP46421.RAjQPlLCgiAj2J2NOFALMIGofeSWq6hZe4X_xA0hnm4yc130_assertion description "[Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46421.RAjQPlLCgiAj2J2NOFALMIGofeSWq6hZe4X_xA0hnm4yc130_provenance.
- NP46427.RAlUs4otBnk6DSYGKdcPml7sNxDWmrNSQDfeJZ2wA6ars130_assertion description "[Our results indicate that the CD28/CTLA4 gene region can contain a novel susceptibility locus for CD and support the hypothesis that CD has an immune system-mediated component.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46427.RAlUs4otBnk6DSYGKdcPml7sNxDWmrNSQDfeJZ2wA6ars130_provenance.
- NP46428.RAn73QHUaMWrcL6znRUabMkuRAiGEtpC0u0OFKUEvPG7g130_assertion description "[The A allele of the CTLA-4 position 49 polymorphism was found on 82.2% of chromosomes in patients with coeliac disease compared with 65.8% in controls (p < 0.0001), mostly in the homozygous form (68.3% in patients versus 47.7% in controls; odds ratio (OR) 2.36, 95% confidence interval (CI) 1.37 to 4.06, p = 0.002).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46428.RAn73QHUaMWrcL6znRUabMkuRAiGEtpC0u0OFKUEvPG7g130_provenance.
- NP46430.RAnDxN79duoxsr1QKfExmR4tgODEBWMB6khlN33AlFOLQ130_assertion description "[Genetic analyses of celiac disease in a Spanish population confirm association with CELIAC3 but not with CELIAC4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46430.RAnDxN79duoxsr1QKfExmR4tgODEBWMB6khlN33AlFOLQ130_provenance.
- NP46431.RAhIclB9lda0aW3uWC5L-AwUbgO9gpPhZ3Qbfuqpb9qJw130_assertion description "[Polymorphisms in immunoregulatory genes: towards individualized immunosuppressive therapy?]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46431.RAhIclB9lda0aW3uWC5L-AwUbgO9gpPhZ3Qbfuqpb9qJw130_provenance.
- NP46438.RAn9mwtLRt7toC0BDaql3jFQHBwiVzb2lD-wK1XbmgSi4130_assertion description "[We identified two previously unknown MS-associated tri-allelic combinations:-509TGFbeta1*C, DRB1*18(3), CTLA4*G and -238TNF*B1,-308TNF*A2, CTLA4*G, which perfectly separate MS cases from controls, at least in the present sample.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46438.RAn9mwtLRt7toC0BDaql3jFQHBwiVzb2lD-wK1XbmgSi4130_provenance.
- NP46442.RAoO9i1m2pAU030oxK-B9X31TP4rEvB4Am8ytL0uSK5dk130_assertion description "[Several other SNPs in the candidate genes, such as CTLA4, HAVCR1, and SUMO4, also had rather small p-values (<0.05), suggesting the associations between them and RA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46442.RAoO9i1m2pAU030oxK-B9X31TP4rEvB4Am8ytL0uSK5dk130_provenance.
- NP46447.RAthdyXD88o2RPbOc1F35YT8ygu5MoxDP_jkNMpZUfVao130_assertion description "[The aim of this study was to investigate the allelic association of a single nucleotide polymorphism in exon 1 of the cytotoxic T-lymphocyte antigen-4 (CTLA4) gene with rheumatoid arthritis (RA) in Chinese people.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46447.RAthdyXD88o2RPbOc1F35YT8ygu5MoxDP_jkNMpZUfVao130_provenance.
- NP46450.RAmGewuxFewAbHia04f5yPWqnHP76lI62YL3ROrlZBgR0130_assertion description "[After combining these data with other reported previously by us, from studies of CTLA4 49 (A/G) and -318 (C/T) polymorphisms, we conclude that the strongest association between CTLA4 gene polymorphisms and RA susceptibility occurs with the 3' UTR polymorphism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46450.RAmGewuxFewAbHia04f5yPWqnHP76lI62YL3ROrlZBgR0130_provenance.
- NP46451.RAvpy_Y2qeP3JV3KZSZs5696_Pn7LDc284WLtI7vSGUqQ130_assertion description "[In the present study, the association of CTLA-4 polymorphism with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) was examined in the Japanese population using the case-control association analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46451.RAvpy_Y2qeP3JV3KZSZs5696_Pn7LDc284WLtI7vSGUqQ130_provenance.
- NP46455.RAhNVP4h9wZq0PAYzP_1ojxyvPZ6-DV46-uzCyt4OkDA8130_assertion description "[Thyroid autoantibody production is influenced by exon 1 and promoter CTLA-4 polymorphisms in patients with Hashimoto's thyroiditis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46455.RAhNVP4h9wZq0PAYzP_1ojxyvPZ6-DV46-uzCyt4OkDA8130_provenance.
- NP46457.RArF4rBViCRQ_Nn5xDfn3M9hHVMw038nZmHEFqAeepm6Q130_assertion description "[To determine the role of cytotoxic T lymphocyte associated antigen 4 (CTLA-4) genetic polymorphisms in susceptibility to systemic sclerosis (SSc, scleroderma).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46457.RArF4rBViCRQ_Nn5xDfn3M9hHVMw038nZmHEFqAeepm6Q130_provenance.
- NP46460.RAtsZcy_ZkICKLAhU5Uxt_2o-pUAbyPfpd_2Sd3G9ljTw130_assertion description "[We studied three single-nucleotide polymorphisms of the cytotoxic T-lymphocyte-associated antigen 4(CTLA4) gene in thymoma patients, nonthymoma early-onset MG patients, and control subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46460.RAtsZcy_ZkICKLAhU5Uxt_2o-pUAbyPfpd_2Sd3G9ljTw130_provenance.
- NP46462.RArBygE2zV55gum1kZjTQwvJfBAV3DByyh1U_2EBZy69A130_assertion description "[Our results suggest that the SNP at position +49 in CDS1 might be associated with the manifestations of MG.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46462.RArBygE2zV55gum1kZjTQwvJfBAV3DByyh1U_2EBZy69A130_provenance.
- NP46465.RAixf8Lmo6jTXGnc8wiuViKoqybnSKPRtDejbHLqdp6-U130_assertion description "[To investigate the possible association of the CT60A/G marker with systemic lupus erythematosus (SLE) in Spanish patients, and to identify the possible CTLA4 haplotype responsible for the association, taking into account other polymorphisms described at positions -1722T/C, -319C/T, +49A/G, and the microsatellite (AT)(n) in the 3'-untranslated region (3'-UTR) of the CTLA4 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46465.RAixf8Lmo6jTXGnc8wiuViKoqybnSKPRtDejbHLqdp6-U130_provenance.
- NP46466.RAi_7icqRnVfXq22vCtvqWHcVLFZq_A5tlrFvxR-HF6ZA130_assertion description "[We have examined the association of systemic lupus erythematosus (SLE) with polymorhisms within the CTLA4 gene that were previously proposed to regulate CTLA-4 function: a single nucleotide polymorphism (SNP) in position +49 of exon 1 and a dinucleotide repeat in the 3' untranslated region (3'UTR).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46466.RAi_7icqRnVfXq22vCtvqWHcVLFZq_A5tlrFvxR-HF6ZA130_provenance.
- NP46471.RAhgGziY4HHR5UR_L_zawrp_TKX_pgnxX5_RETXt3BIz4130_assertion description "[We conclude that the CTLA-4 gene appears to play a significant role in the development of SLE in the Japanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46471.RAhgGziY4HHR5UR_L_zawrp_TKX_pgnxX5_RETXt3BIz4130_provenance.
- NP46477.RApxwv0XYMmsA5Mtj1ZEP0XUuqo_sWxlWRUucwe93ku4A130_assertion description "[Diminished frequencies of the most effective allele for CTLA-4 expression may represent a WG-related susceptibility mutation that accounts, in part, for increased T cell activation and clonal expansion in WG.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46477.RApxwv0XYMmsA5Mtj1ZEP0XUuqo_sWxlWRUucwe93ku4A130_provenance.
- NP46478.RAm8FQYwLj6nmk9kvx38CHmxZc8Xz4opJF8hJh2CurEYs130_assertion description "[To investigate cytokine and cytotoxic T cell antigen-4 (CTLA4) gene polymorphisms and HLA class II alleles in generalised WG.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46478.RAm8FQYwLj6nmk9kvx38CHmxZc8Xz4opJF8hJh2CurEYs130_provenance.
- NP46480.RAs7qcbIEFY-RpK3CBIJFt4rd2TcG6-9B2mkm_dS6EHFE130_assertion description "[Genetic variations in the TNF-alpha, IL-1beta, and CTLA-4 genes could thus be important in WG.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46480.RAs7qcbIEFY-RpK3CBIJFt4rd2TcG6-9B2mkm_dS6EHFE130_provenance.
- NP46491.RAi3LNGTMGMvhjYo6BtBeDthI73hLgYb8eec0cASWWclw130_assertion description "[Association of CTLA-4 gene microsatellite polymorphism with ulcerative colitis in Chinese patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46491.RAi3LNGTMGMvhjYo6BtBeDthI73hLgYb8eec0cASWWclw130_provenance.
- NP46495.RAh6MxHMf1OScCSaXRdNRHRWkbIHWH8hU5fAsvPekxDIg130_assertion description "[DNA samples from AAD subjects (n = 90) and local controls (n = 144 for CTLA-4; n = 576 for AIRE-1) were analyzed for the CTLA-4A/G polymorphism in exon 1 of the CTLA-4 gene and for the common mutant AIRE-1 allele (964de113) in United Kingdom subjects with APS1, by using the restriction enzymes Bst7II and BsrBI, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46495.RAh6MxHMf1OScCSaXRdNRHRWkbIHWH8hU5fAsvPekxDIg130_provenance.
- NP46497.RApiAPQM8Aa7z4JmW0RLe8QypCI2JRFjCgtYV6QGhOREY130_assertion description "[Cytotoxic T-lymphocyte antigen-4 (CTLA-4) gene polymorphism and susceptibility to non-Hodgkin's lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46497.RApiAPQM8Aa7z4JmW0RLe8QypCI2JRFjCgtYV6QGhOREY130_provenance.
- NP46498.RAsH8LVlL1KiuYSYitRObGdbdaR6cUhNgLIeVSkc3DasA130_assertion description "[The CTLA4 -318 C/T genotype was associated with a lower risk of developing gastric MALT lymphoma (odds ratio OR = 0.3; P = .022), whereas CTLA4 49 G/G genotype was linked to a higher risk (OR = 4.1; P = .044).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46498.RAsH8LVlL1KiuYSYitRObGdbdaR6cUhNgLIeVSkc3DasA130_provenance.
- NP46500.RAiAPPm8S3EYeetdogoGLGfvh-34DiCHTChXSf-ZN0ybQ130_assertion description "[We investigated the relationship of CTLA-4 to disease susceptibility and cell profiles in bronchoalveolar lavage (BAL) in Japanese sarcoidosis patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46500.RAiAPPm8S3EYeetdogoGLGfvh-34DiCHTChXSf-ZN0ybQ130_provenance.
- NP46502.RAs-lgMIz4nxhJ8ABUA0MIi3tJOm-YQj2oV_WSxipSpP4130_assertion description "[CTLA4 polymorphisms are associated with the resolution of HCV infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46502.RAs-lgMIz4nxhJ8ABUA0MIi3tJOm-YQj2oV_WSxipSpP4130_provenance.
- NP46503.RAlYBRqMUYN4HJ6KeTJo6z_OTcxNuleCeuGrHoQmy87po130_assertion description "[The CTLA-4 exon 1 (+49 A/G) polymorphism may have a disease-modifying effect in asthmatic airways.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46503.RAlYBRqMUYN4HJ6KeTJo6z_OTcxNuleCeuGrHoQmy87po130_provenance.
- NP46504.RAmu4jIFg9udvNSAQg6yaWWNN3ghyQ-eL0USE3UcXD4ko130_assertion description "[This study suggests a putative role of the CTLA-4 gene polymorphism at position 49 of exon 1 for schizophrenia in the Korean population, although the detailed mechanisms remained to be elucidated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46504.RAmu4jIFg9udvNSAQg6yaWWNN3ghyQ-eL0USE3UcXD4ko130_provenance.
- NP46510.RAihtNJmB49RmKU24sn5zxojll_kic8f5HwyGr6KoOmvU130_assertion description "[A CTLA-4 polymorphism associated with susceptibility to systemic lupus erythematosus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46510.RAihtNJmB49RmKU24sn5zxojll_kic8f5HwyGr6KoOmvU130_provenance.
- NP46512.RAjBEWXWEwI1Da9WZCgB2iUqBAS91kuCH3rGAj3C60mHM130_assertion description "[CTLA-4 dimorphisms in Japanese patients with systemic lupus erythematosus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46512.RAjBEWXWEwI1Da9WZCgB2iUqBAS91kuCH3rGAj3C60mHM130_provenance.
- NP46515.RAmVfl-8qloKCZCqaCJIkGKI34SAcO-CyKqVl1oPImMtk130_assertion description "[Treg frequency is highly heritable within SLE families, with specific variants of the CTLA4 and TGFbeta genes contributing to this trait, while FOXP3 contributes to SLE through mechanisms not involving a modulation of Treg frequency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46515.RAmVfl-8qloKCZCqaCJIkGKI34SAcO-CyKqVl1oPImMtk130_provenance.
- NP46525.RApv9VhcrjkSbCnCMlak-LUtsw4Jv1wzZHFnjmGZA-Gzs130_assertion description "[The purpose of this study was to evaluate the potential effects of CTLA-4 gene polymorphisms in Korean children on asthma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46525.RApv9VhcrjkSbCnCMlak-LUtsw4Jv1wzZHFnjmGZA-Gzs130_provenance.
- NP46528.RAiBEwuUCTG8AVHYshLhJlwn41SE8eg4y_trufxm8Qxk4130_assertion description "[Replication of genetic association studies in asthma and related phenotypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46528.RAiBEwuUCTG8AVHYshLhJlwn41SE8eg4y_trufxm8Qxk4130_provenance.
- NP46529.RAmS2qOseiWwGyPkfihrEKWt0gDlI4LlTEvsvOFvaFr-I130_assertion description "[These results show that allelic variation at the -1722 site influences susceptibility to SLE. This is the first report to our knowledge implicating CTLA-4genotypes at the -1722 locus in susceptibility to any disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46529.RAmS2qOseiWwGyPkfihrEKWt0gDlI4LlTEvsvOFvaFr-I130_provenance.
- NP46531.RAobFgXqXDPzp3sUvfmMWS_6uLciaQReUQV0xoDyzjOJA130_assertion description "[These results show that allelic variation at the -1722 site influences susceptibility to SLE. This is the first report to our knowledge implicating CTLA-4genotypes at the -1722 locus in susceptibility to any disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46531.RAobFgXqXDPzp3sUvfmMWS_6uLciaQReUQV0xoDyzjOJA130_provenance.
- NP46536.RAkeuhmyVVaqSllo9ZDiXhwzD3U0kt6obp9pUqLOnr8zk130_assertion description "[CTLA-4 and HLA gene susceptibility to thyroid-associated orbitopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46536.RAkeuhmyVVaqSllo9ZDiXhwzD3U0kt6obp9pUqLOnr8zk130_provenance.
- NP46537.RAuNg3urZqvV6NKPjVriY6VssUhxlBCidPOjlF0ttZqPY130_assertion description "[In this study, associations of five CTLA4 single nucleotide polymorphisms (-1722A/G, -1661A/G, -318C/T, +49G/A, CT60) with GD risk and GO susceptibility in GD patients were investigated in a Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46537.RAuNg3urZqvV6NKPjVriY6VssUhxlBCidPOjlF0ttZqPY130_provenance.
- NP46542.RAiAd1jDu2OC3OxexB7BQLYAsVaht9S_CjG5Wdj9UsXbc130_assertion description "[To determine the frequency and significance of the exon 1 adenine (A)-guanine (G) base-exchange polymorphism for CTLA-4 in patients with type 1 autoimmune hepatitis, 155 northern European Caucasoid patients and 102 ethnically-matched control subjects were tested by polymerase chain reaction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46542.RAiAd1jDu2OC3OxexB7BQLYAsVaht9S_CjG5Wdj9UsXbc130_provenance.
- NP46547.RAsoRH3f8FLBAIaOXa2jGCe3UDKj7zCTfom5YdB99i83M130_assertion description "[Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46547.RAsoRH3f8FLBAIaOXa2jGCe3UDKj7zCTfom5YdB99i83M130_provenance.
- NP46548.RAjdjIDWkEoQQ8xeqWhVdcYde83CgFomdRkuhpE5W55as130_assertion description "[Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46548.RAjdjIDWkEoQQ8xeqWhVdcYde83CgFomdRkuhpE5W55as130_provenance.
- NP46551.RAuWpsw8iSzirER_jWWe4YFl2mgJ6Q1BzP5tele71g0yk130_assertion description "[Cluster analysis of risk factor genetic polymorphisms in Alzheimer's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46551.RAuWpsw8iSzirER_jWWe4YFl2mgJ6Q1BzP5tele71g0yk130_provenance.
- NP46553.RAnzYDImrVhKo9949ra0Q3sRwbdbytOTqu_VQAcASpid0130_assertion description "[odds ratios (ranging from 1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46553.RAnzYDImrVhKo9949ra0Q3sRwbdbytOTqu_VQAcASpid0130_provenance.
- NP46555.RApqimRj1WrdAH0XEQibc1b5AiNv2085SpTfH1WTcAUIQ130_assertion description "[Genotyping data, the absence of a significant difference in allele frequencies between patients and controls, and survival analyses suggest an increased susceptibility for ARMD in CST3 B/B homozygotes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46555.RApqimRj1WrdAH0XEQibc1b5AiNv2085SpTfH1WTcAUIQ130_provenance.
- NP46556.RAtLZ2xz2OLIJBjCybH7Eo88x79bN-4FZeCWtRyvDpV10130_assertion description "[Four polymorphisms in the promoter and exon 1 of the cystatin C gene (-82GC, -5GA, +4AC, and +148AG) and cystatin C plasma levels were determined in a cohort of 1013 patients with manifest CHD and aged 30 to 70 years participating in an in-hospital rehabilitation program.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46556.RAtLZ2xz2OLIJBjCybH7Eo88x79bN-4FZeCWtRyvDpV10130_provenance.
- NP46563.RAtYVgtycP6Za3qc-TfNl-5Y_S-lv-3tUxGczeb6hUyk4130_assertion description "[A variant in the gene for GM-CSF, I117T, is associated with atopic asthma in a Swiss population of asthmatic children.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46563.RAtYVgtycP6Za3qc-TfNl-5Y_S-lv-3tUxGczeb6hUyk4130_provenance.
- NP46567.RAiC5Tt8iXFc9fclFnghatl5bWcwaw-38CqOlOJ1r1IAc130_assertion description "[ Carriers of the rare allele CRYAB-650*C had an increased likelihood of a noninflammatory, neurodegenerative phenotype characterized by a relatively rapid, primary progressive clinical disease course.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46567.RAiC5Tt8iXFc9fclFnghatl5bWcwaw-38CqOlOJ1r1IAc130_provenance.
- NP46582.RAqq3jvCMKqXVm53Bka_SH6fzcBwkjOh98GVYUOTuyMLI130_assertion description "[C-reactive protein (CRP) gene variation, in particular an rs2794521 variant was recently associated with type 2 diabetes mellitus (T2DM) in Pima Indians.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46582.RAqq3jvCMKqXVm53Bka_SH6fzcBwkjOh98GVYUOTuyMLI130_provenance.
- NP46589.RAkdBYjXNYcROjq6y_WCXd7-iEipp1EyP0tEzln7oXVjg130_assertion description "[Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46589.RAkdBYjXNYcROjq6y_WCXd7-iEipp1EyP0tEzln7oXVjg130_provenance.
- NP46599.RAhOcTBRuqqVgc9W6-cJ7N178LS2qfUDgyF6c4w1V1-Mo130_assertion description "[Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46599.RAhOcTBRuqqVgc9W6-cJ7N178LS2qfUDgyF6c4w1V1-Mo130_provenance.
- NP46600.RAh-r78G-3jm6mlCiAN5YK1bnHwzLAVehFlWmiGQv-XmA130_assertion description "[We present a systematic study of single nucleotide polymorphisms in the corticotropin releasing hormone binding protein gene and their role in the liability for major depression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46600.RAh-r78G-3jm6mlCiAN5YK1bnHwzLAVehFlWmiGQv-XmA130_provenance.
- NP46604.RAu0rwo2c3ZTOOzJB4oGyFZnEBP3yQ8LOFU20ozbUHWEM130_assertion description "[ In Northwest Spain, polymorphism in the CRH gene regulatory region may play a role as a disease susceptibility marker for late onset seronegative RA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46604.RAu0rwo2c3ZTOOzJB4oGyFZnEBP3yQ8LOFU20ozbUHWEM130_provenance.
- NP46606.RAhADrtJ6G45ixsIvrhHukPXww0qUXWpJ5NE5exUGAEvY130_assertion description "[The coding region of the CRF-R1 and CRF-R2 genes was screened in 51 severely obese children (body mass index (BMI)>4 kg/m(2) standard deviations above the age-related mean) using denaturing high-performance liquid chromatography and direct nucleotide sequencing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46606.RAhADrtJ6G45ixsIvrhHukPXww0qUXWpJ5NE5exUGAEvY130_provenance.
- NP46621.RAgpOtnKk3X_AJShXUHt-P3KcbjISWMXJ3cF9FIf3uriw130_assertion description "[The frequency of complement receptor type 1 (CR1) gene polymorphisms in nine families with multiple cases of systemic lupus erythematosus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46621.RAgpOtnKk3X_AJShXUHt-P3KcbjISWMXJ3cF9FIf3uriw130_provenance.
- NP46633.RAiXFx3geaQT5A8klAHl1QRXf38MdEGYEh8q_xdvN7rjU130_assertion description "[We found no differences in the prevalence of genetic risk factors of thrombosis in women with preeclampsia compared with controls, which makes it unlikely that these polymorphisms are risk factors for preeclampsia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46633.RAiXFx3geaQT5A8klAHl1QRXf38MdEGYEh8q_xdvN7rjU130_provenance.
- NP46640.RAkQcGCnkzf_Na6M0K0r8LMECcCTIAyOvde_ZzVMSAffQ130_assertion description "[Our studies have identified two susceptibility loci of OA: COL2A1 and COL9A3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46640.RAkQcGCnkzf_Na6M0K0r8LMECcCTIAyOvde_ZzVMSAffQ130_provenance.
- NP46643.RAhvS4PudWOOV6xdixDxLSGlaS9x_XoFLlahXbebryzPE130_assertion description "[ Early-onset OA demonstrates locus and allelic heterogeneity since the identified variations were in three different collagen genes and each of the six probands had a different mutation. It is also possible that some OA cases represent the mild end of the chondrodysplasia phenotypic spectrum. The major susceptibility alleles in this form of OA, however, remain to be identified.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46643.RAhvS4PudWOOV6xdixDxLSGlaS9x_XoFLlahXbebryzPE130_provenance.
- NP46648.RAskCa4OSqiqK1XISJdx3pk3zjnAMgit_MmqTtFD_4d1I130_assertion description "[An allele of COL9A2 associated with intervertebral disc disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46648.RAskCa4OSqiqK1XISJdx3pk3zjnAMgit_MmqTtFD_4d1I130_provenance.
- NP46658.RAtcUsEvNNREv6siLlrKYZIwk0Rq2JZcXVoytgqq9SoO8130_assertion description "[Numerous mutations of the COL4A5 gene encoding the alpha 5-chain of type IV collagen have been described, establishing the molecular cause of AS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46658.RAtcUsEvNNREv6siLlrKYZIwk0Rq2JZcXVoytgqq9SoO8130_provenance.
- NP46660.RAmmqdrZDlxvDGcDC4Ex58qqgRxqOKnB3rvXQwwSp2NdU130_assertion description "[ Pathogenic COL4A4 mutations were demonstrated in three of the nine (33%) families in whom hematuria segregated with the COL4A3/COL4A4 locus. Two stop codons (R1377X and 2788/91delG) and a glycine substitution (G960R) resulted in hematuria in all 16 members who were tested from these three families. The S969X mutation described here in TBMD for the first time, as well as the R1377X mutation, also occur in autosomal recessive Alport syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46660.RAmmqdrZDlxvDGcDC4Ex58qqgRxqOKnB3rvXQwwSp2NdU130_provenance.
- NP46662.RAuMNFTbrYvmXuLCde9wXyLidMX-T9N5EMUuPuKG6dxB8130_assertion description "[It is possible that superimposing polymorphisms like this one found in the COL3A1 locus may accentuate signals from genetic drift events allowing for visualization of recent dispersal patterns.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46662.RAuMNFTbrYvmXuLCde9wXyLidMX-T9N5EMUuPuKG6dxB8130_provenance.
- NP46666.RAiIIXnuQtEVkbPuHSQJ6Q-KFTpNpqS9J3K9hdXwrjN1g130_assertion description "[The cartilage collagen genes, COL2A1, COL9A1, COL9A2, COL9A3, COL11A1 and COL11A2, were screened for sequence variations in 72 Finnish probands and one US family with primary early-onset hip and/or knee OA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46666.RAiIIXnuQtEVkbPuHSQJ6Q-KFTpNpqS9J3K9hdXwrjN1g130_provenance.
- NP46668.RAhLJ2otZRy9aE5DLy0dag5cI1FRqwfoTbZQnh3LXbIy0130_assertion description "[These results indicate that genetic markers could contribute to the understanding of the natural history of this disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46668.RAhLJ2otZRy9aE5DLy0dag5cI1FRqwfoTbZQnh3LXbIy0130_provenance.
- NP46676.RApZku9yEHR-dc5oe3IxtGLBgcx0kY22-WQoB20as4Kj4130_assertion description "[This study is the first to confirm the association between COL1A2 and IAs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46676.RApZku9yEHR-dc5oe3IxtGLBgcx0kY22-WQoB20as4Kj4130_provenance.
- NP46678.RAneYUDvbhQ8QzngqJhLS9FrV4sO6bNpPLIKduoCq-syo130_assertion description "[Tests of linkage and association of the COL1A2 gene with bone phenotypes' variation in Chinese nuclear families.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46678.RAneYUDvbhQ8QzngqJhLS9FrV4sO6bNpPLIKduoCq-syo130_provenance.
- NP46680.RAjYYTwy6_llR6rYmswkRzvAECVTTDpRlNkuhg41NnzrI130_assertion description "[Osteogenesis imperfecta (OI) is a heritable bone fragility disorder that in the majority of cases is caused by mutations in COL1A1 or COL1A2, the genes that encode the two collagen type I alpha chains, alpha1(I) and alpha2(I).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46680.RAjYYTwy6_llR6rYmswkRzvAECVTTDpRlNkuhg41NnzrI130_provenance.
- NP46681.RAsWaL9MKkCVVPzRZ61Ue_3_zTOCmOxnABnoH8-yTh8do130_assertion description "[Association of functional microsatellites in the human type I collagen alpha2 chain (COL1A2) gene with systemic sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46681.RAsWaL9MKkCVVPzRZ61Ue_3_zTOCmOxnABnoH8-yTh8do130_provenance.
- NP46683.RAouVIJ5WdE3hCR4aF63vdtG9umscE0Rat0A-_FsrFqkU130_assertion description "[No correlation of five gene polymorphisms with periodontal conditions in a Greek population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46683.RAouVIJ5WdE3hCR4aF63vdtG9umscE0Rat0A-_FsrFqkU130_provenance.
- NP46685.RAv3__Sh_-BWt6jc8Tk7Tp2sa2bAQjL034yEOK6wzcWPw130_assertion description "[ Children with bone cancer are significantly taller than the reference population, which may be influenced by the genotype for the Fok I polymorphism of the VDR gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46685.RAv3__Sh_-BWt6jc8Tk7Tp2sa2bAQjL034yEOK6wzcWPw130_provenance.
- NP46693.RAirS4_5wY6E4fHZq2FDU3IREgylXZfIHduwxXFUirff0130_assertion description "[Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I alpha 1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46693.RAirS4_5wY6E4fHZq2FDU3IREgylXZfIHduwxXFUirff0130_provenance.
- NP46695.RAs14C4g1EVXkHtLw5kcogbfB7DJbRoxVdvgJQtdqsZ4Q130_assertion description "[ COLIA1 Sp1 polymorphism may be a genetic risk factor related to intervertebral disc degeneration in older people. Previously reported associations between the COLIAI Sp1 genotype and lower BMD or QUS values, higher levels of DPD/Cr, and an increased fracture risk in either men or women could not be confirmed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46695.RAs14C4g1EVXkHtLw5kcogbfB7DJbRoxVdvgJQtdqsZ4Q130_provenance.
- NP46699.RAuxPi3W8p2Q_NWHvTqVdxhV_XSPu82ncYv7NvGRqqkwA130_assertion description "[Rapid genotyping of the osteoporosis-associated polymorphic transcription factor Sp1 binding site in the COL1A1 gene by pyrosequencing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46699.RAuxPi3W8p2Q_NWHvTqVdxhV_XSPu82ncYv7NvGRqqkwA130_provenance.
- NP46706.RAupSHpSLHEMP8nzVIT7xJdfR9QOsaSiII8parOgjtkSU130_assertion description "[The results suggest that whole-body vibration is a risk factor for symptomatic IDD. Moreover, whole-body vibration had an additive effect with genetic risk factors increasing the likelihood of belonging to the IDD-phenotype group. Of the independent genetic markers, IL1A -889T allele had strongest association with IDD-phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46706.RAupSHpSLHEMP8nzVIT7xJdfR9QOsaSiII8parOgjtkSU130_provenance.
- NP46709.RAtmz2uIHj9UqjznCuLjAO0uxzj75iqIaFnh4ihiyiuTM130_assertion description "[with a prevalence ratio of 2:1, and our gender-specific associations indicate that genetic factors involving COL11A2 play a specific role in the etiology of OPLL exclusively in males.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46709.RAtmz2uIHj9UqjznCuLjAO0uxzj75iqIaFnh4ihiyiuTM130_provenance.
- NP46716.RAsmuLtUXhMET0eBFABcUve28tcSDUt-92y0zsX8FbpPo130_assertion description "[Despite the small sample size, this novel analysis method identified an sMRI component including brain areas previously reported to be abnormal in schizophrenia and an associated genetic component containing several putative schizophrenia risk genes. Thus, we identified multiple genes potentially underlying specific structural brain abnormalities in schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46716.RAsmuLtUXhMET0eBFABcUve28tcSDUt-92y0zsX8FbpPo130_provenance.
- NP46718.RApiEr8kTqnTS4Q62UeE2RNZAyUeX5HhEylU8WLSrsa2k130_assertion description "[Variants within the cannabinoid receptor 1 gene (CNR1) have been shown to be directly associated with the hebephrenic form of schizophrenia in a Japanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46718.RApiEr8kTqnTS4Q62UeE2RNZAyUeX5HhEylU8WLSrsa2k130_provenance.
- NP46719.RAmH51tsq95eY5CgVQEAmME0gGeKtwsOJkHzHgh4RgBh4130_assertion description "[Neither CNR1 nor CHRNA7 variation appears to alter the risk of schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46719.RAmH51tsq95eY5CgVQEAmME0gGeKtwsOJkHzHgh4RgBh4130_provenance.
- NP46722.RAphk4RWzVCHM0gIucf-19KtepM4DBaHyg952xydMcXm8130_assertion description "[Association study of cannabinoid receptor gene (CNR1) alleles and drug dependence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46722.RAphk4RWzVCHM0gIucf-19KtepM4DBaHyg952xydMcXm8130_provenance.
- NP46723.RAhJqsaWcQNKP06qq9yTLLOqOyAON486XuQkYYJGB4fmQ130_assertion description "[CNGB3 mutations account for 50% of all cases with autosomal recessive achromatopsia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46723.RAhJqsaWcQNKP06qq9yTLLOqOyAON486XuQkYYJGB4fmQ130_provenance.
- NP46726.RAmW-Fvnk23kspsi1dTzXfcFInZl3Pits9nvKof-k3gYM130_assertion description "[ Our study provided evidence against an association between angiotensinogen M235T or chymase gene CMA/B polymorphisms and the presence of incipient or overt nephropathy in Caucasian patients with type II diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46726.RAmW-Fvnk23kspsi1dTzXfcFInZl3Pits9nvKof-k3gYM130_provenance.
- NP46730.RAtZPc-9b_LgyCVboSKFlyDIL8kRUVOG4HkU8qAlpGMow130_assertion description "[Absence of association between a variant of the mast cell chymase gene and atopic dermatitis in an Italian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46730.RAtZPc-9b_LgyCVboSKFlyDIL8kRUVOG4HkU8qAlpGMow130_provenance.
- NP46733.RAo36siTs0stS6xiMhdwuvmvrReCrbLkLU_NksuzjQG5A130_assertion description "[Association of polymorphisms in the mast cell chymase gene promoter region (-1903 g/A) and (TG)n(GA)m repeat downstream of the gene with bronchial asthma in children.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46733.RAo36siTs0stS6xiMhdwuvmvrReCrbLkLU_NksuzjQG5A130_provenance.
- NP46734.RArg4TCVK2d5MvqOmTe_MfCzI7ZZWW4oI_1bOk_g1G8vg130_assertion description "[Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46734.RArg4TCVK2d5MvqOmTe_MfCzI7ZZWW4oI_1bOk_g1G8vg130_provenance.
- NP46735.RAr3c1QG8eTsH2N9bHHb9Dt_Qw0ordkmPM3H0B-ytSl84130_assertion description "[This preliminary observation leads to hypothesize a possible involvement of the CLOCK gene polymorphism in the sleep disregulations in MDD and BP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46735.RAr3c1QG8eTsH2N9bHHb9Dt_Qw0ordkmPM3H0B-ytSl84130_provenance.
- NP46736.RAlmtvYfUrWgXpiq1g_JKr3U2Q44lXrZIcWobM0BV4Nxo130_assertion description "[ Some subjects showing remission after acute treatment relapsed within 6 months, despite undertaking a maintenance treatment; the causes could be heterogeneous, but CLOCK gene variants may influence the outcome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46736.RAlmtvYfUrWgXpiq1g_JKr3U2Q44lXrZIcWobM0BV4Nxo130_provenance.
- NP46737.RAsIZY9gCTpBmmCeyEXjw-1WZCfFzcD5D8I-PrFHsq31M130_assertion description "[Our results indicate that CLOCK genotype may be a predictor of fluvoxamine treatment response in Japanese MDD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46737.RAsIZY9gCTpBmmCeyEXjw-1WZCfFzcD5D8I-PrFHsq31M130_provenance.
- NP46740.RAqbcaEOzpDO2Dcjb_FjhfYLmXIwC7ysH-6GFBiKUw9cs130_assertion description "[We conclude that an interaction between clozapine and the CLOCK gene polymorphism 3111 T/C substitution could explain persistent daytime sleepiness in a significant proportion of patients treated with clozapine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46740.RAqbcaEOzpDO2Dcjb_FjhfYLmXIwC7ysH-6GFBiKUw9cs130_provenance.
- NP46741.RAinJGLwTjbo-EPs6EYdBFjb_-HxS4l2Vj_ynt6Whc2kQ130_assertion description "[Actimetric evidence that CLOCK 3111 T/C SNP influences sleep and activity patterns in patients affected by bipolar depression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46741.RAinJGLwTjbo-EPs6EYdBFjb_-HxS4l2Vj_ynt6Whc2kQ130_provenance.
- NP46743.RAou-P3eM3EC4Rb9mfPR-mvcM3HT7-7OHl485Jwam_dik130_assertion description "[This preliminary observation leads to hypothesize a role for the CLOCK gene polymorphism in the regulation of long-term illness recurrence in bipolar disorder. Given the post-hoc nature of the finding, replication in independent samples is necessary to confirm it.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46743.RAou-P3eM3EC4Rb9mfPR-mvcM3HT7-7OHl485Jwam_dik130_provenance.
- NP46745.RArRfC3X4RmScdSpto0xuIJ-ygK1iFVi3QNAHQiTVVOl0130_assertion description "[Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46745.RArRfC3X4RmScdSpto0xuIJ-ygK1iFVi3QNAHQiTVVOl0130_provenance.
- NP46749.RAr4J-aGSCC2OghJoNVDaDjg22oM5u0KXl8GIaTjMwllM130_assertion description "[We characterized the genetic variation and haplotype diversity of four hypertension candidate genes (CLCNKA, CLCNKB, BSND, NEDD4L) in four different ethnic groups (Caucasian Americans, African-Americans, Han Chinese, and Mexican-Americans).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46749.RAr4J-aGSCC2OghJoNVDaDjg22oM5u0KXl8GIaTjMwllM130_provenance.
- NP46751.RAmFREYhP9RmnHlTD0ydg93izL58HBVsF_-TCfFVfCdio130_assertion description "[ In 56 of 94 patients with a classical picture of ARO, TCIRG1-dependent recessive mutations were found. In contrast, ClCN7 mutations were found in 12 cases (13%) of severe osteopetrosis, but only 7 of them had two recessive mutations identified: in 6 of these 7 cases, central nervous system manifestations were noted, and these patients had a poor prognosis. The remaining five cases were heterozygous for a ClCN7 mutation, including two brothers from a large family with a history of ADO-II in which the presence of a second ClCN7 mutation was formally excluded. Despite an early and severe clinical presentation, these five patients all reached adulthood, suggesting that the degree of dominant interference with chloride channel function can vary widely. Our findings suggest that recessive ClCN7-dependent ARO may be associated with CNS involvement and have a very poor prognosis, whereas heterozygous ClCN7 mutations cause a wide range of phenotypes even in the same family, ranging from early severe to nearly asymptomatic forms. These findings have prognostic implications, might complicate prenatal diagnosis of human osteopetroses, and could be relevant to the management of these patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46751.RAmFREYhP9RmnHlTD0ydg93izL58HBVsF_-TCfFVfCdio130_provenance.
- NP46752.RAsg1bA9fwlF7hXM1VWLBdjgMlAWo7P69_dJVIH5nOGYU130_assertion description "[ We observed a significant association of CLCN7 polymorphisms with the variance of BMD and bone resorption marker levels in postmenopausal women and with the variability of the ADOII phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46752.RAsg1bA9fwlF7hXM1VWLBdjgMlAWo7P69_dJVIH5nOGYU130_provenance.
- NP46756.RArB1Rh8GBZqa0T1bZhtnfd2z-NTJ_21n8dEU_e2shrQE130_assertion description "[These findings demonstrate that CLCA2 is frequently inactivated in breast cancer by promoter region hypermethylation, which makes it an excellent candidate for the 1p31 breast cancer tumour suppressor gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46756.RArB1Rh8GBZqa0T1bZhtnfd2z-NTJ_21n8dEU_e2shrQE130_provenance.
- NP46770.RAiFs5s9zygj5mrQZgAVxyf2JB2k8LPXXT5nG89lGCdIw130_assertion description "[The nACHR4 594C/T polymorphism in Alzheimer disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46770.RAiFs5s9zygj5mrQZgAVxyf2JB2k8LPXXT5nG89lGCdIw130_provenance.
- NP46771.RAtoNOA8ot9NN3WeW45B_Y8hGTD24TMTZgDq-bc7-stWs130_assertion description "[These data suggest that the CHRNA4 gene or a closely linked gene might be one of the susceptibility factors for FCs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46771.RAtoNOA8ot9NN3WeW45B_Y8hGTD24TMTZgDq-bc7-stWs130_provenance.
- NP46776.RAnctoWDBNLenj_4X1n3kfXKS_pnEkuaDpmVIxgbrNbk4130_assertion description "[These findings suggested that genetic polymorphisms of the neuronal nAChR genes might be related to the pathogenesis of sporadic AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46776.RAnctoWDBNLenj_4X1n3kfXKS_pnEkuaDpmVIxgbrNbk4130_provenance.
- NP46778.RAoBd4mekEXluF5ekOSBZO8lS3_vH-gafMlQ4GsiF28j4130_assertion description "[Personalised prescribing for asthma--is pharmacogenetics the answer?]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP46778.RAoBd4mekEXluF5ekOSBZO8lS3_vH-gafMlQ4GsiF28j4130_provenance.