Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP48022.RAnRUh_26hs0Nfut0tah68-15dnGqHuILCEgn2SUU4iUs130_assertion description "[This study is the largest to date investigating AR sequence variants, sex steroid levels, and prostate cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48022.RAnRUh_26hs0Nfut0tah68-15dnGqHuILCEgn2SUU4iUs130_provenance.
- NP48023.RAoZFfJd048BDh3RBaQNVnodAKTIjq5koXGTjvU5wtVnk130_assertion description "[The purpose of this study was to analyse the frequency and type of mutations in the coding region of androgen receptor (AR) and to determine the role of polymorphisms in the intron 1 of ERalpha, exon 5 of ERbeta, intron 7 of progesterone, exon 7 of the aromatase (CYP19) and exon 9 of VDR genes in the risk of prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48023.RAoZFfJd048BDh3RBaQNVnodAKTIjq5koXGTjvU5wtVnk130_provenance.
- NP48028.RAv_hfnkyvhOaw6u-sZjuSV8QzoFMS1OsCC07xBtgS-3c130_assertion description "[We study the CAG repeat region in exon 1 of the androgen receptor (AR) and the TaqI polymorphism in exon 9 of the vitamin D receptor (VDR) and the association with prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48028.RAv_hfnkyvhOaw6u-sZjuSV8QzoFMS1OsCC07xBtgS-3c130_provenance.
- NP48029.RAlsKQAgcJ6C1ytCQM_gYkXaAZ8-xttozosydKikW2Vf8130_assertion description "[Our results suggest an association between the VDR and AR gene polymorphisms, and the histopathological score and age at diagnosis in Mexican patients with PCa, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48029.RAlsKQAgcJ6C1ytCQM_gYkXaAZ8-xttozosydKikW2Vf8130_provenance.
- NP48031.RAmvcBJ8XpLtZqhKdu5-gTyknLOSjTFKCCY1TK91bZ8gg130_assertion description "[Prostate cancer risk may be influenced by single genetic variants in the hormone-regulating genes androgen receptor (AR), cytochrome P450 (CYP17), and steroid-5-alpha-reductase type 2 (SRD5A2).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48031.RAmvcBJ8XpLtZqhKdu5-gTyknLOSjTFKCCY1TK91bZ8gg130_provenance.
- NP48033.RAjYQdw72SLD6yuvJJ1YPytDSR-baDsb5Ouo1ZFZN_DNM130_assertion description "[In conclusion, mutations are frequently found in genes that control androgen action and metabolism, but are seldom found in genes active in the early phase of sex determination and differentiation. Mutations in AR, SRD5A2 or WT1 seem to be associated not only with hypospadias but also with micropenis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48033.RAjYQdw72SLD6yuvJJ1YPytDSR-baDsb5Ouo1ZFZN_DNM130_provenance.
- NP48042.RAvwcM5mUIeYgC7Zb9a6JIu50gBXIy0PbTMybe28EFE54130_assertion description "[We report penile length (PL) responses to testosterone enanthate (TE) therapy for micropenis, and the relevance of the V89L polymorphism of SRD5A2 encoding the 5alpha-reductase type 2 and CAG repeat length polymorphism of AR encoding the androgen receptor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48042.RAvwcM5mUIeYgC7Zb9a6JIu50gBXIy0PbTMybe28EFE54130_provenance.
- NP48044.RAgZ70Wn4h-cVR8yFmD4j2-YANjaUIdZw2brmL8xj-Trk130_assertion description "[The association between androgen receptor gene polymorphisms and benign prostatic hyperplasia was investigated among 510 men randomly selected from Olmsted County, Minnesota.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48044.RAgZ70Wn4h-cVR8yFmD4j2-YANjaUIdZw2brmL8xj-Trk130_provenance.
- NP48049.RAsB0J6gQR7YTH9ljSIN_pMYBRteA1NePXyLoM0v0YeR4130_assertion description "[The androgen receptor gene polymorphism and clinical picture of androgen deficiency syndrome during aging male of men's population in Wroclaw.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48049.RAsB0J6gQR7YTH9ljSIN_pMYBRteA1NePXyLoM0v0YeR4130_provenance.
- NP48052.RAiTGDFIppVOlfdPzqyQire_6zBzBvrDoEYj26CdUaxkg130_assertion description "[The shorter CAG repeat of the AR gene is associated with more severe CAD, which suggests a role for the sensitivity to androgens in the increased frequency of CAD in males.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48052.RAiTGDFIppVOlfdPzqyQire_6zBzBvrDoEYj26CdUaxkg130_provenance.
- NP48055.RAmuzoTB32u3Phe6LirZBZVTy3NcMiRhR0HbxFRg0tENE130_assertion description "[To determine if the androgen receptor gene is associated with male pattern baldness, we compared allele frequencies of the androgen receptor gene polymorphisms (StuI restriction fragment length polymorphism and two triplet repeat polymorphisms) in cases with cosmetically significant baldness (54 young and 392 older men) and controls (107 older men) with no indication of baldness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48055.RAmuzoTB32u3Phe6LirZBZVTy3NcMiRhR0HbxFRg0tENE130_provenance.
- NP48057.RAlxAX3lCU_O1R_5EThYWSEt255RWxa18IEnk_AUGTp1A130_assertion description "[Mutations in three genes (PSEN1, PSEN2, and APP) have been identified in patients with early-onset (<65 years) Alzheimer's disease (AD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48057.RAlxAX3lCU_O1R_5EThYWSEt255RWxa18IEnk_AUGTp1A130_provenance.
- NP48059.RAtgNOfhXZW7B7sDTn5X4XV18NrfM0zgt1Id7YBKCfF2Y130_assertion description "[Consistent with previous studies, the pattern of Abeta deposition in familial AD differs from that in sporadic AD, with higher striatal and somewhat lower cortical PiB retention in familial AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48059.RAtgNOfhXZW7B7sDTn5X4XV18NrfM0zgt1Id7YBKCfF2Y130_provenance.
- NP48067.RAqv3pyH11jHaxASk6MVOX6sPmZEr5HbbGzNyIksV0ofY130_assertion description "[Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48067.RAqv3pyH11jHaxASk6MVOX6sPmZEr5HbbGzNyIksV0ofY130_provenance.
- NP48072.RApEEXbe1X17NJibZYRPoPZPwkjG9NbiLEgFWZbJq8Hv4130_assertion description "[Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48072.RApEEXbe1X17NJibZYRPoPZPwkjG9NbiLEgFWZbJq8Hv4130_provenance.
- NP48073.RAnJHQifs8IqiMXRoqihqrS5XhszbwpmMoi2wBPs_zImE130_assertion description "[No significant differences between villages were observed. When these data were compared to those of other populations studied so far, a significant association between APOH allele frequencies and latitude was observed. We hypothesize that this association reflects differences in diet composition across different climatic zones.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48073.RAnJHQifs8IqiMXRoqihqrS5XhszbwpmMoi2wBPs_zImE130_provenance.
- NP48075.RAlO2VgYqCOIge2cOevQiE6GOlv1nEvEBhi6g3GTsXG7U130_assertion description "[To study the association between apolipoprotein H (apoH) gene polymorphism and cerebral apoplexy among the Hans in Changsha, Hunan Province.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48075.RAlO2VgYqCOIge2cOevQiE6GOlv1nEvEBhi6g3GTsXG7U130_provenance.
- NP48076.RAoRpcnvqzD4vYf2HKaPrbUVOOeXpEk1oRTDuzgscgjPk130_assertion description "[To clarify the consequences of the valine/leucine polymorphism at position 247 of the beta(2)-glycoprotein I (beta(2)GPI) gene in patients with antiphospholipid syndrome (APS), by investigating the correlation between genotypes and the presence of anti-beta(2)GPI antibody.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48076.RAoRpcnvqzD4vYf2HKaPrbUVOOeXpEk1oRTDuzgscgjPk130_provenance.
- NP48078.RAsPTmFA2YXCaYhgu88_ExT3hKmBZHD45gRbrf1gO_yCk130_assertion description "[The present investigation is aimed at examining the Apolipoprotein E (APOE) genotypic influence on coronary heart disease (CHD) risk in northwest India (Punjab), where this disease is emerging as a major threat to public-health care system.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48078.RAsPTmFA2YXCaYhgu88_ExT3hKmBZHD45gRbrf1gO_yCk130_provenance.
- NP48079.RAto0r_HcLlpEj9d1hI0aJQxUtY223_qEiCTYszLRT-wQ130_assertion description "[The poliovirus receptor related 2 (PRR2) and apolipoprotein E genes and coronary heart disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48079.RAto0r_HcLlpEj9d1hI0aJQxUtY223_qEiCTYszLRT-wQ130_provenance.
- NP48082.RAjDukaD69QCnoFI7LJBhGqS6WmFyLIF8OIYRrOgXenC0130_assertion description "[Genetic polymorphism of the apoE gene might contribute to the determination of serum lipid profile and the development of CHD among Han Chinese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48082.RAjDukaD69QCnoFI7LJBhGqS6WmFyLIF8OIYRrOgXenC0130_provenance.
- NP48088.RAomE9Vs8NcKPeA9XXOzsugEFt3B7ThQYVKDzBgFolcWk130_assertion description "[We examined contribution of three polymorphisms frequently associated with individual differences in cognition (Catechol-O-Methyl-Transferase Val158Met, Brain-Derived-Neurotrophic-Factor Val66Met, and Apolipoprotein E epsilon4) and a vascular risk factor (hypertension) in a sample of 189 volunteers (age 18-82).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48088.RAomE9Vs8NcKPeA9XXOzsugEFt3B7ThQYVKDzBgFolcWk130_provenance.
- NP48091.RAhwBudIYVys4GFAxrQif9yFy9CyAvcsFDQJstdA4qw7g130_assertion description "[Apolipoprotein E (apoE) gene polymorphism is one of the most well-studied genetic markers for vascular diseases, including hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48091.RAhwBudIYVys4GFAxrQif9yFy9CyAvcsFDQJstdA4qw7g130_provenance.
- NP48095.RAg3fPXiSFNjCqJPNijTxYYCMJyj0Od5E8Hr8moG3lLIs130_assertion description "[The relationship between apolipoprotein E epsilon2/epsilon3/epsilon4 polymorphisms and hypertension: a meta-analysis of six studies comprising 1812 cases and 1762 controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48095.RAg3fPXiSFNjCqJPNijTxYYCMJyj0Od5E8Hr8moG3lLIs130_provenance.
- NP48103.RAqJlg2de9xm5kmeWweAKs-nQYqX8PQoQiOH-5l05-IOQ130_assertion description "[We have identified 4 novel loci associated with circulating lipids. We also show that in addition to those that are largely associated with LDL-C, genetic loci mainly associated with circulating triglycerides and HDL-C are also associated with risk of CAD. These findings potentially provide new insights into the biological mechanisms underlying lipid metabolism and CAD risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48103.RAqJlg2de9xm5kmeWweAKs-nQYqX8PQoQiOH-5l05-IOQ130_provenance.
- NP48109.RAn_xEM-D37t_wH9fkVTyUblXHkR69W7Ybt0K6OZwdyTI130_assertion description "[The most common mutations were K790X (19.5%), P664L (6.0%), FH-Tonami-1 (6.0%), IVS15-3C>A (5.5%) and FH-Tonami-2 (4.5%), whereas the other mutations were rare. No apolipoprotein B (apoB) mutations responsible for familial ligand-defective apoB-100 (FDB)]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48109.RAn_xEM-D37t_wH9fkVTyUblXHkR69W7Ybt0K6OZwdyTI130_provenance.
- NP48112.RArxEZup7yV8h70ruVnhKRNPBcvelhwF4jZ6si-y8toBM130_assertion description "[Apolipoprotein E genotype affects plasma lipid response to atorvastatin in a gender specific manner.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48112.RArxEZup7yV8h70ruVnhKRNPBcvelhwF4jZ6si-y8toBM130_provenance.
- NP48113.RAm7KqvsDbEtgy4PgVOLbDbufi3HHX56kG3mdGg8Ub0to130_assertion description "[Microcrystalline chitosan is ineffective to decrease plasma lipids in both apolipoprotein E epsilon 4 carriers and non-carriers: a long-term placebo-controlled trial in hypercholesterolaemic volunteers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48113.RAm7KqvsDbEtgy4PgVOLbDbufi3HHX56kG3mdGg8Ub0to130_provenance.
- NP48115.RAvrNfyXofeVugV5VdCCOify5u_jotHV6H5BthHK4iVK4130_assertion description "[Influence of apolipoprotein E genotype on the reliability of the Friedewald formula in the estimation of low-density lipoprotein cholesterol concentrations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48115.RAvrNfyXofeVugV5VdCCOify5u_jotHV6H5BthHK4iVK4130_provenance.
- NP48121.RAoOE_w87hL2v9olkH9Z99LAKT17Io-Cz5fsd7gmx1pcQ130_assertion description "[To compare differences in severity and type of electroencephalography (EEG) abnormalities between early and late onset Alzheimer's disease (AD) and to assess the influence of APOE genotype on this association, in order to understand the biological differences in AD according to age at onset]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48121.RAoOE_w87hL2v9olkH9Z99LAKT17Io-Cz5fsd7gmx1pcQ130_provenance.
- NP48126.RAgLutXwWU6srsFFng2xopFWDSsdq2FTM_cyagl6izX5k130_assertion description "[Hippocampal but not amygdalar volumes were associated with presence of one or two APOE epsilon4 alleles in MCI and mild AD, while there was no association of APOE epsilon4 allele with rCBF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48126.RAgLutXwWU6srsFFng2xopFWDSsdq2FTM_cyagl6izX5k130_provenance.
- NP48127.RAlutYWmcfEykxEEwcw7jz6VwfktI5MTKLaqKOKu49q6k130_assertion description "[Over a 36-week follow-up period, no significant difference in the effects of donepezil, galantamine and rivastigmine on a variety of functional and cognitive parameters was observed in a large number of apoE-genotyped patients with mild to moderate AD recruited within the framework of a national project representative of the scenario usually encountered in actual clinical practice in Italy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48127.RAlutYWmcfEykxEEwcw7jz6VwfktI5MTKLaqKOKu49q6k130_provenance.
- NP48129.RAk8DI2L4O6q9iMg0xuISXkS35-3-udmBTSKHD7i5pWIs130_assertion description "[Genetically, AD cases with capillary CAA were strongly associated with the APOE epsilon4 allele compared to those lacking capillary CAA and to controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48129.RAk8DI2L4O6q9iMg0xuISXkS35-3-udmBTSKHD7i5pWIs130_provenance.
- NP48138.RAnedxqKSA68FZUYSoVVX0pJ38XyIeixa-v8H0P7Dea4I130_assertion description "[There were significantly more APOE epsilon4 alleles alone (P = 0.02) or in combination with BChE-K (P = 0.02) among early-onset CAD patients compared to late-onset CAD ones or controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48138.RAnedxqKSA68FZUYSoVVX0pJ38XyIeixa-v8H0P7Dea4I130_provenance.
- NP48142.RAn2WbsDPJqr_8Pqv564GGUvcquIXVBsbo3hqYvL6U9_8130_assertion description "[Thus genetic factors play a role not only in formation of coronary atherosclerosis but determine the course of ischemic heart disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48142.RAn2WbsDPJqr_8Pqv564GGUvcquIXVBsbo3hqYvL6U9_8130_provenance.
- NP48143.RAgmcxgFWapCnTxojr0413_-fTQEWRNqxKMbxasJzwvq0130_assertion description "[For a modest panel of selected genotypes, CHD-risk estimates incorporating CRFs and genotype-risk factor interactions were more effective than risk estimates that used CRFs alone.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48143.RAgmcxgFWapCnTxojr0413_-fTQEWRNqxKMbxasJzwvq0130_provenance.
- NP48144.RAovD1WuZO-3NFDSz31vqIQMjHZgJmMH13EOINtpZswdM130_assertion description "[An application of the patient rule-induction method for evaluating the contribution of the Apolipoprotein E and Lipoprotein Lipase genes to predicting ischemic heart disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48144.RAovD1WuZO-3NFDSz31vqIQMjHZgJmMH13EOINtpZswdM130_provenance.
- NP48148.RAnJ-k3-N8P_tF_0tEP-DHc6WWUn-56e9D0wF-UzRsBV0130_assertion description "[, we present evidence that combinations of SNPs in APOE and LPL identify subgroups of individuals at substantially increased risk of IHD beyond that associated with smoking, diabetes and hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48148.RAnJ-k3-N8P_tF_0tEP-DHc6WWUn-56e9D0wF-UzRsBV0130_provenance.
- NP48149.RAlIpTua5-y1oh4XxqRIryGeYCcae8G9WyjDnZqWXfGbU130_assertion description "[Variation in 5' promoter region of the APOE gene contributes to predicting ischemic heart disease (IHD) in the population at large: the Copenhagen City Heart Study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48149.RAlIpTua5-y1oh4XxqRIryGeYCcae8G9WyjDnZqWXfGbU130_provenance.
- NP48151.RAltovugSK6nZ95uKgeCk0nAyW_9-w6PTXm2HDbC8Z3g8130_assertion description "[Associations between the polymorphism of apolipoprotein E, which plays an important role in cholesterol metabolism and cholesterol gallstone formation, have been reported recently.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48151.RAltovugSK6nZ95uKgeCk0nAyW_9-w6PTXm2HDbC8Z3g8130_provenance.
- NP48153.RAlVK9htcs3I4aP4khHIJ-M7y_V0OltF-RyIFSi8xix9Y130_assertion description "[Apolipoprotein E genotypes as predictors of high-risk groups for developing hyperlipidemia in kidney transplant recipients undergoing sirolimus treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48153.RAlVK9htcs3I4aP4khHIJ-M7y_V0OltF-RyIFSi8xix9Y130_provenance.
- NP48154.RAvK6f_EIgpEWbgDhAhE4gHmORtrO4uEEhJ6XeExvksvE130_assertion description "[The great majority of patients with type III hyperlipidemia (type III HLP) are homozygous for the epsilon2 allele of the APOE gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48154.RAvK6f_EIgpEWbgDhAhE4gHmORtrO4uEEhJ6XeExvksvE130_provenance.
- NP48157.RAk22yCygFea9bWdcBVecjc9saCyj9CkcfoHQ-ph6Ggrc130_assertion description "[The association found in this study between allele E2 and lower total cholesterol level had been reported in previous studies. We have also observed that the frequency of genotype E2/E3 and E2/E4 was significantly higher in patients with normal total serum cholesterol level compared to patients with abnormal cholesterol (P=0.003 OR 2.4 95% CI; 1.3-4.6). Our data needs to be repeated in a larger population with more information for serum LDL and HDL levels and their subgroups.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48157.RAk22yCygFea9bWdcBVecjc9saCyj9CkcfoHQ-ph6Ggrc130_provenance.
- NP48158.RApvXFozWb45uX7qwE3CHwExnk5VXSsfUwr_yc47ahFmA130_assertion description "[Effect of apolipoprotein E genotype on apolipoprotein B-100 metabolism in normolipidemic and hyperlipidemic subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48158.RApvXFozWb45uX7qwE3CHwExnk5VXSsfUwr_yc47ahFmA130_provenance.
- NP48171.RAl6VI2oJSsTXJGke7vZT50WxqSo_HDXmdE5CdKDzLzOM130_assertion description "[Risk of carotid atherosclerosis associated with genetic polymorphisms of apolipoprotein E and inflammatory genes among arsenic exposed residents in Taiwan.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48171.RAl6VI2oJSsTXJGke7vZT50WxqSo_HDXmdE5CdKDzLzOM130_provenance.
- NP48175.RAjKEAbMtpgCS-dJg62CB0X0yvO_sbm64thWFJFfAZcoM130_assertion description "[However, the relationship between apolipoprotein E (APOE) polymorphism and markers of atherosclerosis is still controversial.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48175.RAjKEAbMtpgCS-dJg62CB0X0yvO_sbm64thWFJFfAZcoM130_provenance.
- NP48176.RAtL9MDSOaWa269JtjouH_rHb9KeYV1hIzan1X_qOggf0130_assertion description "[Apolipoprotein E gene and early age-related maculopathy: the Atherosclerosis Risk in Communities Study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48176.RAtL9MDSOaWa269JtjouH_rHb9KeYV1hIzan1X_qOggf0130_provenance.
- NP48180.RAi5Q3VzdgERZ4PlDNzp_zGF0Trb7NDwY_9Ae7mKa5lCc130_assertion description "[We investigated the frequency of Tyr402His polymorphism of the complement factor H (CFH) gene, Ser69Ala polymorphism at LOC387715, rs11200638 polymorphism of the HTRA1 gene and different apolipoprotein E (ApoE) alleles in Hungarian patients with AMD in order to determine the disease risk conferred by these factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48180.RAi5Q3VzdgERZ4PlDNzp_zGF0Trb7NDwY_9Ae7mKa5lCc130_provenance.
- NP48182.RAuqgGniaHmYm1eX_RK-PmfUhZMouxf6JChKs3lQBlxu4130_assertion description "[Of the five extended APOE haplotypes common in the general population, two were found to be significantly associated with AMD, namely G-G-G-G-epsilon2 (odds ratio OR, 1.59; 95% confidence interval CI, 1.19-2.12) and T-G-A-G-epsilon4 (OR, 0.76; 95% CI, 0.58-0.99).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48182.RAuqgGniaHmYm1eX_RK-PmfUhZMouxf6JChKs3lQBlxu4130_provenance.
- NP48184.RAtfJ4gPhPjqgNmAU4XcbKsbMDkyrE7RnIq3SjIFiCFWw130_assertion description "[To further clarify the association of AMD with APOE and smoking history, future studies should consider both factors simultaneously.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48184.RAtfJ4gPhPjqgNmAU4XcbKsbMDkyrE7RnIq3SjIFiCFWw130_provenance.
- NP48187.RAiaGe0FcFCCKwVGl9vmDAuAM3i13TjUdf0beMa0tlzug130_assertion description "[A possible association between apolipoprotein E polymorphisms and age-related macular degeneration has been investigated numerous times, with conflicting results.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48187.RAiaGe0FcFCCKwVGl9vmDAuAM3i13TjUdf0beMa0tlzug130_provenance.
- NP48197.RAk-9TwL5FFd-BAZWgItM9u69KneRJrdcQ7YnZfA6csG8130_assertion description "[Given that many markers of stroke risk are modifiable or treatable, our findings have implications for assessment, prevention, and treatment of cognitive decline.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48197.RAk-9TwL5FFd-BAZWgItM9u69KneRJrdcQ7YnZfA6csG8130_provenance.
- NP48199.RAnkxRS1nsRgQg-LuCGPDr4wnTDHi8tedeJDUXqZPhtpY130_assertion description "[To determine the role of APOE alleles in PD and age of onset in PD at time of diagnosis, 203 patients with incident PD and 187 healthy control subjects from Western and Southern Norway were investigated according to their APOE allele status.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48199.RAnkxRS1nsRgQg-LuCGPDr4wnTDHi8tedeJDUXqZPhtpY130_provenance.
- NP48208.RAjyhWhHy1L0BU-Ll8Ga6bCW-lYUGDiCkjU_rTB4FLaWA130_assertion description "[To determine whether the frequency of dopamine receptor genetic variants and APOE alleles in patients with PD with and without chronic visual hallucinations resembles the pattern previously documented in patients with Alzheimer disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48208.RAjyhWhHy1L0BU-Ll8Ga6bCW-lYUGDiCkjU_rTB4FLaWA130_provenance.
- NP48218.RAi7ZKlrI6_M-RDfXsaNwL7X3Hm4r1a7oCQB725ssXOss130_assertion description "[The presence of the epsilon4 allele increases the risk for CVE and cardiac death in patients with T2DM and ESRD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48218.RAi7ZKlrI6_M-RDfXsaNwL7X3Hm4r1a7oCQB725ssXOss130_provenance.
- NP48221.RAlsRSJfL5SIQ3NnFahwM94mpzuDkba_A4644x59VSnG8130_assertion description "[APOE and cerebral amyloid angiopathy in the elderly.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48221.RAlsRSJfL5SIQ3NnFahwM94mpzuDkba_A4644x59VSnG8130_provenance.
- NP48222.RAiJLiIbk14IAKmGWhxpKEGZCSHgR7rOv8BXeEqRhfmYA130_assertion description "[Influence of cholesteryl ester transfer protein, peroxisome proliferator-activated receptor alpha, apolipoprotein E, and apolipoprotein A-I polymorphisms on high-density lipoprotein cholesterol, apolipoprotein A-I, lipoprotein A-I, and lipoprotein A-I:A-II concentrations: the Prospective Epidemiological Study of Myocardial Infarction study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48222.RAiJLiIbk14IAKmGWhxpKEGZCSHgR7rOv8BXeEqRhfmYA130_provenance.
- NP48228.RAnn6OXfch3ss_WxrIuKXZnmMZGOl6agU-yJI69R5VWUw130_assertion description "[Our data suggest a synergistic effect between the APOE and AGT polymorphisms and early MI.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48228.RAnn6OXfch3ss_WxrIuKXZnmMZGOl6agU-yJI69R5VWUw130_provenance.
- NP48230.RAqkpRGmJhwH3e2nRTePZi66NKqniWZMumAJxv4jTzBos130_assertion description "[ These results suggest that the efficiency of cholesterol transport from the mother to the embryo is affected by the maternal apo E genotype and extend the role of apo E and its disease associations to modulation of embryonic development and malformations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48230.RAqkpRGmJhwH3e2nRTePZi66NKqniWZMumAJxv4jTzBos130_provenance.
- NP48234.RAqvrhAdLNg6re8AlWfIMsqY1M70PEMrDr8M1jODauDOQ130_assertion description "[Association of APOE polymorphism with the change of brain function in the early stage of aneurysmal subarachnoid hemorrhage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48234.RAqvrhAdLNg6re8AlWfIMsqY1M70PEMrDr8M1jODauDOQ130_provenance.
- NP48237.RAgNKi2GDRI9SpQbGw7awx0o5Vrr7LrXj68CMetK5_sFk130_assertion description "[Presence of the epsilon4 allele poses a minor risk for late cognitive impairment after the subacute phase of aneurysmal SAH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48237.RAgNKi2GDRI9SpQbGw7awx0o5Vrr7LrXj68CMetK5_sFk130_provenance.
- NP48245.RAiQUMgyvNhLE2Lo7D_DqksogeMM08mrEDwbFsNwD4_js130_assertion description "[Pooled analyses of MS cases were also performed to assess the influence of APOE epsilon genotype on disease severity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48245.RAiQUMgyvNhLE2Lo7D_DqksogeMM08mrEDwbFsNwD4_js130_provenance.
- NP48246.RAhZn_sQo1z_tlpTbK2KAe4DzYXTspQShcc_XPKglzqAE130_assertion description "[In Kuwaitis, a population with low MS prevalence, no statistically significant associations between APOE genetic polymorphism and susceptibility to MS could be established, but there was a trend towards a lower APOE2 frequency with MS and towards increased frequency of APOE4 in female patients and with severe disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48246.RAhZn_sQo1z_tlpTbK2KAe4DzYXTspQShcc_XPKglzqAE130_provenance.
- NP48247.RAsQC8ZIQZO7HfEzMDi9I0ByQcGCCL6oJlfQnfCLfDQ58130_assertion description "[The authors examined the influence of APOE and human leukocyte antigen-DRB1-DQB1 polymorphisms on the course of multiple sclerosis in 871 patients, 773 with relapsing and 98 with primary progressive disease, and 348 control subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48247.RAsQC8ZIQZO7HfEzMDi9I0ByQcGCCL6oJlfQnfCLfDQ58130_provenance.
- NP48252.RAjaHJSSPyGwAzihdokqQVKVe8SF0NeS7lWKjU135-9iU130_assertion description "[These findings indicate that the effects of tamoxifen on plasma triglyceride levels are modified by APOE polymorphism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48252.RAjaHJSSPyGwAzihdokqQVKVe8SF0NeS7lWKjU135-9iU130_provenance.
- NP48253.RArdteLm3I0-aZr0SJ9HrOd1anQ46_BnU-1tGYZ3Gc91c130_assertion description "[Association between the apolipoprotein E genotypes and breast cancer patients in Taiwanese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48253.RArdteLm3I0-aZr0SJ9HrOd1anQ46_BnU-1tGYZ3Gc91c130_provenance.
- NP48254.RAg_f0b81D-ityGaaqUekfb5m5pu6VYE15Y2JpslV4GZU130_assertion description "[Differences in tau and apolipoprotein E polymorphism frequencies in sporadic frontotemporal lobar degeneration syndromes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48254.RAg_f0b81D-ityGaaqUekfb5m5pu6VYE15Y2JpslV4GZU130_provenance.
- NP48256.RAu3szvmqGAoiqQcy1mLx0eFLsLyhP_f1NhlbZLY9M5DM130_assertion description "[Low HDL is strongly associated with adverse coronary and cerebrovascular outcomes. Our results indicate that low HDL levels are also associated with more severe WMC lesions on MRI. Dietary or medical adjustment of HDL levels could have important implications for treatment and prevention of cerebral WMC, cerebrovascular and neurodegenerative diseases such as stroke and dementia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48256.RAu3szvmqGAoiqQcy1mLx0eFLsLyhP_f1NhlbZLY9M5DM130_provenance.
- NP48258.RAt-Dp7PaQgcWnvNmQQ6gppmguNjybBySCkuD4VERS07E130_assertion description "[Late-onset depression: genetic, vascular and clinical contributions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48258.RAt-Dp7PaQgcWnvNmQQ6gppmguNjybBySCkuD4VERS07E130_provenance.
- NP48260.RAo5cs-9lTEN4pPChXXssEEbqGbLqrnpeSHlEVS3yjOa0130_assertion description "[Allelic variability in D21S11, but not in APP or APOE, is associated with cognitive decline in Down syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48260.RAo5cs-9lTEN4pPChXXssEEbqGbLqrnpeSHlEVS3yjOa0130_provenance.
- NP48262.RArlKk4pebAhqqn2O0ktUKvUwUQDTMqT1zcUjY7P6NIM4130_assertion description "[The apolipoprotein E (Apo E) polymorphism has been reported to influence some lipid profile abnormalities associated with obesity in childhood.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48262.RArlKk4pebAhqqn2O0ktUKvUwUQDTMqT1zcUjY7P6NIM4130_provenance.
- NP48267.RAm5Emx5iLLjjsNN843mSnOk9ynk1h6ZSqOHM1a0YusO8130_assertion description "[BMI, ApoE genotype and plasma level of lipid were measured in 324 obese children.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48267.RAm5Emx5iLLjjsNN843mSnOk9ynk1h6ZSqOHM1a0YusO8130_provenance.
- NP48268.RAh9QxqTStSFjYmqB6hqshls9SWWcjxxx0q5z0sk5GtXA130_assertion description "[, central obesity, low HDL cholesterol, and CRP polymorphisms are major determinants of higher hsCRP levels in Chinese patients receiving treatment with rosuvastatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48268.RAh9QxqTStSFjYmqB6hqshls9SWWcjxxx0q5z0sk5GtXA130_provenance.
- NP48274.RAjLisLhZMtG3zjxPRBPWfdu3ztoHnVmLlDmv-i9iaZJI130_assertion description "[Presence of the apolipoprotein E (APOE) epsilon4 allele is linked to an increased risk to develop Alzheimer's dementia (AD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48274.RAjLisLhZMtG3zjxPRBPWfdu3ztoHnVmLlDmv-i9iaZJI130_provenance.
- NP48275.RAleduCeI4Gx-ysFTc7z5IYmTpanzah2wx_SDimaWeWKw130_assertion description "[There were no interactions between MPS and other baseline risk factors for dementia, including gender, education, race, family history of dementia, stroke, and apolipoprotein E-e4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48275.RAleduCeI4Gx-ysFTc7z5IYmTpanzah2wx_SDimaWeWKw130_provenance.
- NP48276.RAou2lCd9txaCLx0tyhIHykbsGkFo60d1yIENG4bGrOSA130_assertion description "[Effects of apolipoprotein E-epsilon4 and -epsilon2 in amnestic mild cognitive impairment and dementia in Shanghai: SCOBHI-P.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48276.RAou2lCd9txaCLx0tyhIHykbsGkFo60d1yIENG4bGrOSA130_provenance.
- NP48277.RAqgA30n-WNhn5XLQjC0DAe9e9m1SJmqxIe4PRGrbFDME130_assertion description "[After adjustment for age, education, and hormone use, HRs for death were significantly higher in women with the APOE 2/4, 3/4, or 4/4 genotype who developed dementia (HR=3.74; 95% CI=2.81-4.99) and the APOE 2/3 genotype (HR=3.23; 95%=CI=1.97-5.28) than in women without dementia and the APOE 3/3 genotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48277.RAqgA30n-WNhn5XLQjC0DAe9e9m1SJmqxIe4PRGrbFDME130_provenance.
- NP48302.RAu6QNVKGGdhe5lq3IOK2K0s9Zj38U1YquMYlfxSEUmNY130_assertion description "[ Our study suggests that apoE epsilon2 is a risk factor for atherothrombosis, cardioembolism, and intracerebral hemorrhage, whereas epsilon4 is a risk factor for atherothrombosis, intracerebral hemorrhage, and subarachnoid hemorrhage. The occurrence of stroke may be affected by interaction between age and apoE gene polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48302.RAu6QNVKGGdhe5lq3IOK2K0s9Zj38U1YquMYlfxSEUmNY130_provenance.
- NP48303.RAl2cMJKA6kf9Cu4EXj4rCZY1UbZrguwk59VPUIDWby_g130_assertion description "[ Our data suggest that polymorphisms in the apoE gene are significantly associated with LDL-C levels and increased risk of carotid plaque formation in men but not IMT in either men or women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48303.RAl2cMJKA6kf9Cu4EXj4rCZY1UbZrguwk59VPUIDWby_g130_provenance.
- NP48308.RAnEbII08A0vNWQ9gEgJTLmWSSvxDA1vXVRXDuagJQva4130_assertion description "[ These results show that the reduced renal excretion of uric acid in patients with gout is mediated by high levels of VLDL and by the high prevalence of the E2 allele of apolipoprotein E.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48308.RAnEbII08A0vNWQ9gEgJTLmWSSvxDA1vXVRXDuagJQva4130_provenance.
- NP48318.RAqSVRjkOTymn56b8p8wb9eyarnYQFGcrY5lIEfPcTvY0130_assertion description "[Effects of the apolipoprotein E polymorphism on plasma lipid levels and cardiovascular disease risk in a Mediterranean population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48318.RAqSVRjkOTymn56b8p8wb9eyarnYQFGcrY5lIEfPcTvY0130_provenance.
- NP48320.RAu2ScW8HMH1oLCM492nzhuj1Fv15YfAFqp4XADZb-MP8130_assertion description "[APOE polymorphism is associated with lipid profile, but not with arterial stiffness in the general population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48320.RAu2ScW8HMH1oLCM492nzhuj1Fv15YfAFqp4XADZb-MP8130_provenance.
- NP48321.RAvghBV_vkNbTuMiZFZQaioUT5NFjgQASitC4A5ZxkVsE130_assertion description "[Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48321.RAvghBV_vkNbTuMiZFZQaioUT5NFjgQASitC4A5ZxkVsE130_provenance.
- NP48324.RAqYMQxVoaByeY8QbzHBm1dXz6xP40lvHYncBR7wixGrQ130_assertion description "[, the ApoE epsilon4 isoform is a genetic factor that might influence the age at onset of TLE.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48324.RAqYMQxVoaByeY8QbzHBm1dXz6xP40lvHYncBR7wixGrQ130_provenance.
- NP48327.RAkKzDRnECgDDk6EmWXhgeu9QqwmrMC9i42_qWVRhNh4Q130_assertion description "[ Our findings show a significant genetic association of APOE polymorphism with outcome after spontaneous aneurysmal SAH. Genetic factors thus seem to explain a part of individual differences in the recovery of SAH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48327.RAkKzDRnECgDDk6EmWXhgeu9QqwmrMC9i42_qWVRhNh4Q130_provenance.
- NP48332.RApV7fGmtQfk0oDk7KEgtGZQ3lBtQr-8_SwsWtlNvW_Wg130_assertion description "[ The allele 17 of apoCII may be an independent risk factor for CHD in Han population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48332.RApV7fGmtQfk0oDk7KEgtGZQ3lBtQr-8_SwsWtlNvW_Wg130_provenance.
- NP48334.RAuoyVV7bjbqsVppN42qF7xzz5m95UQ7obdYYjhDynw7I130_assertion description "[Apolipoprotein D gene polymorphism: a new genetic marker for type 2 diabetic subjects in Nauru and south India.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48334.RAuoyVV7bjbqsVppN42qF7xzz5m95UQ7obdYYjhDynw7I130_provenance.
- NP48336.RApNEP-v_qD-LdIqZkOj-uLOOz6fnoL0zXyge5MjZdJc0130_assertion description "[Apolipoprotein gene cluster on chromosome 19. Definite localization of the APOC2 gene and the polymorphic Hpa I site associated with type III hyperlipoproteinemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48336.RApNEP-v_qD-LdIqZkOj-uLOOz6fnoL0zXyge5MjZdJc0130_provenance.
- NP48337.RAlz3M0lg0_VXMyoPHXqkK369igMSFMTmuxcqjsZ6ujZc130_assertion description "[A population association study of four candidate genes (hexokinase II, glucagon-like peptide-1 receptor, fatty acid binding protein-2, and apolipoprotein C-II) with type 2 diabetes and impaired glucose tolerance in Japanese subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48337.RAlz3M0lg0_VXMyoPHXqkK369igMSFMTmuxcqjsZ6ujZc130_provenance.
- NP48340.RAmiN8GiGpMhHLtvAS973zqGqo7TwrTfaG5O025eIpwqQ130_assertion description "[To identify clinical manifestations and neuropsychological effects of Alzheimer disease (AD) in apolipoprotein (ApoE) e4 carriers and to investigate the relationships between ApoE HhaI polymorphism and apolipoprotein C1 (APOC1) HpaI polymorphism in Taiwanese patients with AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48340.RAmiN8GiGpMhHLtvAS973zqGqo7TwrTfaG5O025eIpwqQ130_provenance.
- NP48341.RAmLR1zJKaoji1ImXFvpj7U8P1g69vHGni3UZlDoIwnlk130_assertion description "[PVRL2, TOMM40 and APOC1, could also yield a predisposition to LOAD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48341.RAmLR1zJKaoji1ImXFvpj7U8P1g69vHGni3UZlDoIwnlk130_provenance.
- NP48348.RAjRyLpoqY0HKv_bNy4aYuPpYTIHYF1DLJjANRpdpFc9Y130_assertion description "[Chromosome 19 locus apolipoprotein C-II association with multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48348.RAjRyLpoqY0HKv_bNy4aYuPpYTIHYF1DLJjANRpdpFc9Y130_provenance.
- NP48352.RAvCsvrvp6UXKIGfalm_W9mvFs2VmlSUTUi-VFwdIg9fI130_assertion description "[Our results emphasize the need to account for complex multi-gene influences and interactions when assessing the molecular pathology of multifactorial medical entities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48352.RAvCsvrvp6UXKIGfalm_W9mvFs2VmlSUTUi-VFwdIg9fI130_provenance.
- NP48356.RAtKPZH8vf0FQQnI-4gNmUBoklePEm-Ooea0w3IUhhEcI130_assertion description "[Association of polymorphisms of the apolipoprotein B gene with coronary heart disease in Han Chinese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48356.RAtKPZH8vf0FQQnI-4gNmUBoklePEm-Ooea0w3IUhhEcI130_provenance.
- NP48370.RAteaHiswltWYMWiwc9euuJUy6ubOT2tCrQkBa-8tD6bE130_assertion description "[Mutation detection rate and spectrum in familial hypercholesterolaemia patients in the UK pilot cascade project.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48370.RAteaHiswltWYMWiwc9euuJUy6ubOT2tCrQkBa-8tD6bE130_provenance.
- NP48371.RApZNhVz2w5X3bHXuotRuwl5AsllgFeEUQwasZRTYUNJ8130_assertion description "[Novel mutations identification in exon 4 of LDLR gene in patients with moderate hypercholesterolemia in a Venezuelan population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48371.RApZNhVz2w5X3bHXuotRuwl5AsllgFeEUQwasZRTYUNJ8130_provenance.
- NP48380.RApXAbZJVXvaueegcHF-OMDSrYY2N6rUSBdxahQFv30yg130_assertion description "[, haplotype analysis of the apoB gene using multiple diallelic markers might be a useful marker for Korean CAD patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48380.RApXAbZJVXvaueegcHF-OMDSrYY2N6rUSBdxahQFv30yg130_provenance.
- NP48385.RAhzX5-xDWdWB8xdvppma77QLefylQIoRjkwuduBQ9Hmo130_assertion description "[ Despite the small size of most studies and the incomplete understanding of the effects of these polymorphisms on lipid metabolism and on final clinical implications, the findings suggest that EcoRI and SpIns/Del polymorphisms significantly increase the risk of CAD and MI. Despite the rarity of the allelic variant of EcoRI polymorphism, its presence is strongly related to the occurrence of CAD/MI. Moreover, there is a high consistency between small and large studies. The results on SpIns/Del polymorphism seem the most interesting and reliable, considering both the number of subjects analysed and the consistency of the evidence of its effect on lipid levels. These results need to be confirmed by larger and appropriately powered studies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48385.RAhzX5-xDWdWB8xdvppma77QLefylQIoRjkwuduBQ9Hmo130_provenance.
- NP48389.RAv1ugIvHfCwplAvCU6UX_MY02aTe4rOgMGF8xWKWi-1Y130_assertion description "[Six polymorphic loci (etm1240, etm1231, etm1234, APOB, etm1241, and etm1242) in a 274-kb interval within an ET gene candidate region (ETM2) were analyzed in Singaporean individuals with a family history of ET (n = 52) and compared to Singaporean controls older than age 65 (n = 49).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48389.RAv1ugIvHfCwplAvCU6UX_MY02aTe4rOgMGF8xWKWi-1Y130_provenance.
- NP48396.RAtZC4DsVHlg1-KICD4t53DkrYtRWairG2KX9KVYBQYvw130_assertion description "[An intronic single nucleotide polymorphism in ABCA1 and the APOE epsilon3 allele are associated with reduced LDLc lowering by statins and identify individuals who may be resistant to maximal LDLc lowering by statins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP48396.RAtZC4DsVHlg1-KICD4t53DkrYtRWairG2KX9KVYBQYvw130_provenance.