Nanopublications

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NP58444.RAqamg-jwGVQOTGDRxi42dT6TlGENs3g2XoZVa35lp1o4130_assertion description "[The present study represents the first four-digit allele genotyping of HLA-A and -B in Japanese Behcet's disease (BD) patients and controls using a new genotyping method (named the PCR-SSOP-Luminex method) to determine the association of certain HLA-A or -B alleles with BD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58444.RAqamg-jwGVQOTGDRxi42dT6TlGENs3g2XoZVa35lp1o4130_provenance.
NP58464.RAuN-4a5BK2IBGKj2_qrJz3hbmGUUwUAuYXsXStEywr8E130_assertion description "[Tumor necrosis factor-alpha polymorphisms in ulcerative colitis-associated colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58464.RAuN-4a5BK2IBGKj2_qrJz3hbmGUUwUAuYXsXStEywr8E130_provenance.
NP58465.RAsnYj52eKgfmBcZDjumW_ctL6W49aPo6UUCQTjqAP9sI130_assertion description "[To investigate the association between common single nucleotide polymorphisms (SNPs) in inflammatory response-related genes such as interleukin (IL)-6, IL-8, tumor necrosis factor alpha (TNFalpha), peroxisome proliferators-activated receptor gamma (PPARgamma), intercellular adhesion molecule-1 (ICAM-1) and the risk of colorectal cancer (CRC) in a group of Greek patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58465.RAsnYj52eKgfmBcZDjumW_ctL6W49aPo6UUCQTjqAP9sI130_provenance.
NP58467.RAhGl2r1BFDSHdPzX7_B2GnrF0goB4aGuTVrKTt9DNzvk130_assertion description "[The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58467.RAhGl2r1BFDSHdPzX7_B2GnrF0goB4aGuTVrKTt9DNzvk130_provenance.
NP58479.RAi5RoGMdrg5PbTlOqIfW0RAXFLX6pdIgNQ_VfCV3_ydU130_assertion description "[Our results emphasize the need to account for complex multi-gene influences and interactions when assessing the molecular pathology of multifactorial medical entities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58479.RAi5RoGMdrg5PbTlOqIfW0RAXFLX6pdIgNQ_VfCV3_ydU130_provenance.
NP58480.RAjUgwuWseEq6A9obELjkXJnNvl_sy6W4RcN5gGin0yuM130_assertion description "[ In an RA population from NW Spain the frequencies of HLA-DRB1 and TNF microsatellite alleles in patients with extra-articular manifestations were not significantly different to those without extraarticular disease, although there was a trend towards increased frequency of HLA-DRB1*0101 in patients with nodular disease. There was no evidence for an interaction between HLA-DRB1 and TNF alleles in relation to the expression of EAM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58480.RAjUgwuWseEq6A9obELjkXJnNvl_sy6W4RcN5gGin0yuM130_provenance.
NP58484.RArrmplNN24YhnWLMWbQHHDjrF5zAWW-T6pY2tRyTiCIc130_assertion description "[Association of death receptor 4 haplotype 626C-683C with an increased breast cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58484.RArrmplNN24YhnWLMWbQHHDjrF5zAWW-T6pY2tRyTiCIc130_provenance.
NP58503.RAprwg0dAZgHzYCIC-KVi-olgyW5XXIaumc5SePbdAUZA130_assertion description "[ These TNF-RI and TNF-RII polymorphisms were not found to be associated with susceptibility to or severity of RA in the Dutch population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58503.RAprwg0dAZgHzYCIC-KVi-olgyW5XXIaumc5SePbdAUZA130_provenance.
NP58514.RAuekL5zmiLXUJqNl5Zm5uiVy5hXOWb8qA3Aibw6H5gx0130_assertion description "[We investigated the hypothesis that low-penetrance mutations in genes (TNFRSF1A, MEFV and NALP3/CIAS1) associated with hereditary periodic fever syndromes (HPFs) might be risk factors for AA amyloidosis among patients with chronic inflammatory disorders, including rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), Crohn's disease, undiagnosed recurrent fevers and HPFs themselves.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58514.RAuekL5zmiLXUJqNl5Zm5uiVy5hXOWb8qA3Aibw6H5gx0130_provenance.
NP58525.RAsWO5MLP8EBJmlCKoDfgkrWw4zXcs2JrJiA3hT0BPA_4130_assertion description "[Tumor necrosis factor receptor II gene polymorphism and severity of rheumatoid arthritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58525.RAsWO5MLP8EBJmlCKoDfgkrWw4zXcs2JrJiA3hT0BPA_4130_provenance.
NP58526.RAkClhO63dcgEixGzPyWAokfGwK4ZuclPLU0YRQhcRGC0130_assertion description "[Up to 200 unrelated German RA and JRA patients each and 300-400 healthy controls have been genotyped for HLA-DRB1, TNFa, TNFA -238a/g, TNFA -308a/g, TNFA -857c/t, TNFR1 -609g/t, TNFR1 P12P, TNFR2 del 15bp, IKBL -332a/g, IKBL -132t/a, IKBL C224R, CTLA4 -318c/t, CTLA4 T17A, PTPRC P57P, MIF -173g/c, the MIF and IFNG microsatellites as well as for D17S795, D17S807, D17S1821 by polyacrylamide gel electrophoresis, single-strand conformation polymorphism analysis, restriction fragment length polymorphism analysis or allele specific hybridization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58526.RAkClhO63dcgEixGzPyWAokfGwK4ZuclPLU0YRQhcRGC0130_provenance.
NP58530.RAiTGy3MhWPuRiIghse55ZEeIMCkvkEoLGWbZqztSgJmw130_assertion description "[The tumour necrosis factor receptor superfamily member 1b 676T>G polymorphism in relation to response to infliximab and adalimumab treatment and disease severity in rheumatoid arthritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58530.RAiTGy3MhWPuRiIghse55ZEeIMCkvkEoLGWbZqztSgJmw130_provenance.
NP58532.RAmnpBn6_doIIStGiCbMKOlwUEohfqjAK9B6CqiJfJjWM130_assertion description "[The presence of the A2 allele in the TNFR2 gene may predispose subjects to obesity and higher leptin levels, which may in turn predispose them to insulin resistance or vice versa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58532.RAmnpBn6_doIIStGiCbMKOlwUEohfqjAK9B6CqiJfJjWM130_provenance.
NP58536.RAqvF3kC2vPYXwf3iiK4Aep7JxeD087P4d0T0ougc28ak130_assertion description "[The recent identification of an SLE disease susceptibility locus near the TNFR2 locus (TNFR p75) suggested the hypothesis that genetically driven differences in soluble TNFR2 production could play a role in the genetic susceptibility to SLE.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58536.RAqvF3kC2vPYXwf3iiK4Aep7JxeD087P4d0T0ougc28ak130_provenance.
NP58537.RAsbhAR3VhLxcEQGLBBNvQIesTTqpiGDwvupk_zS0CDLY130_assertion description "[A biallelic VNTR within a 42-bp region in the TNFR2 gene promoter was determined by polymerase chain reaction in 88 SLE patients and 95 healthy control subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58537.RAsbhAR3VhLxcEQGLBBNvQIesTTqpiGDwvupk_zS0CDLY130_provenance.
NP58541.RAh_5IitIiW-Blz_nIkRQCCyz__bdWTKi5dVysUSpfizA130_assertion description "[We recently reported the association of the allele coding for Arg at the position 196 (196R: nucleotide nt 587G) of tumor necrosis factor receptor 2 (TNFR2, TNF-R75) with systemic lupus erythematosus (SLE) in Japanese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58541.RAh_5IitIiW-Blz_nIkRQCCyz__bdWTKi5dVysUSpfizA130_provenance.
NP58553.RAjd9jdGVQF2mB5yFAoJV_NXaOj2aB-Vr3gx_N5dvADhA130_assertion description "[ Our data fail to support previous association findings for TNFRSF1B and CLCNKB at the chromosome 1p36 locus implicated in hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58553.RAjd9jdGVQF2mB5yFAoJV_NXaOj2aB-Vr3gx_N5dvADhA130_provenance.
NP58555.RAoXVl5rvpO9TBoDgDmh6kRhsaCdL8RN5Lh-NDPrASydE130_assertion description "[ The results of this study provide evidence of association between an SNP in the TNFRII gene and RA, the strongest association being observed in patients with a family history. No evidence of association between RA and TNFRI was demonstrated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58555.RAoXVl5rvpO9TBoDgDmh6kRhsaCdL8RN5Lh-NDPrASydE130_provenance.
NP58556.RAmRD8s5qKba5iJCO6kBZVECh_5uLvTkc0BKomgP63gbU130_assertion description "[ Although we observed no associations between known TNFR SNPs or haplotypes and RA, significant racial differences were observed at both loci. Comparison of these data with other published frequencies of TNFRSF1A and TNFRSF1B genotypes according to race suggests that the distribution in African American, Caucasian, and Asian populations differs significantly. These striking racial/ethnic differences in TNFR SNP frequencies may influence the likelihood of familial RA, severe disease, or response to TNF inhibitors and may have important evolutionary implications.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58556.RAmRD8s5qKba5iJCO6kBZVECh_5uLvTkc0BKomgP63gbU130_provenance.
NP58560.RAg8Rll-73Up_TsiswBHrdn_44Udit8ktXdsvViAAPi88130_assertion description "[These data constitute the first report of an association of TNFRSF1A and TNFRSF1B polymorphisms with CD in a Caucasian population and address the role of TNFR mutations in determining clinical heterogeneity in CD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58560.RAg8Rll-73Up_TsiswBHrdn_44Udit8ktXdsvViAAPi88130_provenance.
NP58567.RAjtO3d4yKjFpoLBUdd5LMLxgbPKRU-M9XJpANBaYq0wg130_assertion description "[These data suggest that inflammation or an active immune response may induce an increased amount of HTLV-I-infected T cells, leading to a high provirus load.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58567.RAjtO3d4yKjFpoLBUdd5LMLxgbPKRU-M9XJpANBaYq0wg130_provenance.
NP58574.RAvyYuQQpTRbeu-wzgszJ6CyQM951_iwO5OLB4LgsFxUk130_assertion description "[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58574.RAvyYuQQpTRbeu-wzgszJ6CyQM951_iwO5OLB4LgsFxUk130_provenance.
NP58575.RApVzY4DfVt1x3O8KK5RsdknS5jT-m1ev9j-h_U8ul6uI130_assertion description "[In two independent human populations, the less common allele of SNP rs3850641 in TNFSF4 was significantly more frequent (P <or= 0.05) in individuals with myocardial infarction than in controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58575.RApVzY4DfVt1x3O8KK5RsdknS5jT-m1ev9j-h_U8ul6uI130_provenance.
NP58577.RAtufDK0Nei4pGsOFYAgrLNuK3nndpWTIKigeJZXuL520130_assertion description "[In conclusion, TNNT2 deletion allele could be associated with a predisposition to prominent left ventricular hypertrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58577.RAtufDK0Nei4pGsOFYAgrLNuK3nndpWTIKigeJZXuL520130_provenance.
NP58578.RAnGy0WJ2zbdGLwIIz_c1YgxVSDV6aejVPKGMJSvbF5_E130_assertion description "[Troponin T mutations had a low prevalence (3.3%, including a newly described Phe110Leu mutation) and were associated with heterogeneous clinical expression and outcome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58578.RAnGy0WJ2zbdGLwIIz_c1YgxVSDV6aejVPKGMJSvbF5_E130_provenance.
NP58580.RAsVowMQNuYcKtUGGkw_TQ-LSqQtfiBC0lsYuixtgoPaQ130_assertion description "[MYH7 appears as the most frequently mutated gene in our FDCM population (approximately 10%), and mutation carriers present with delayed onset, in contrast to TNNT2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58580.RAsVowMQNuYcKtUGGkw_TQ-LSqQtfiBC0lsYuixtgoPaQ130_provenance.
NP58581.RApAQxDxuVXZo6hrjnJrl02BdH8UXhGPBKTBROVOjMJV0130_assertion description "[Genotype-phenotype correlative studies have implicated 8 particular mutations that cause hypertrophic cardiomyopathy (HCM) as `benign defects,` associated with near-normal survival: N232S, G256E, F513C, V606M, R719Q, and L908V of beta-myosin heavy chain (MYH7); S179F of troponin T (TNNT2); and D175N of alpha-tropomyosin (TPM1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58581.RApAQxDxuVXZo6hrjnJrl02BdH8UXhGPBKTBROVOjMJV0130_provenance.
NP58583.RAl12Ampc9TiUvAb5S3-DmXTSVVCLOoBffhtRafxdE178130_assertion description "[ Multiple gene mutations occurring in HCM families may result in a more severe clinical phenotype because of a double dose effect. This highlights the importance of screening the entire panel of HCM genes even after a single mutation has been identified.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58583.RAl12Ampc9TiUvAb5S3-DmXTSVVCLOoBffhtRafxdE178130_provenance.
NP58586.RAjM8SqMya3FAbG7dEEneg9Jui_XX7SA6wwnM8w3WOpAQ130_assertion description "[left ventricular noncompaction is within the diverse spectrum of cardiac morphologies triggered by sarcomere protein gene defects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58586.RAjM8SqMya3FAbG7dEEneg9Jui_XX7SA6wwnM8w3WOpAQ130_provenance.
NP58589.RArtMNd-x18S3f7SqPru2eNeg5_xQlgRyb65L_Cvpaf_o130_assertion description "[Germline variations of the topoisomerase IIalpha gene as risk factors for primary gastric B-cell lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58589.RArtMNd-x18S3f7SqPru2eNeg5_xQlgRyb65L_Cvpaf_o130_provenance.
NP58591.RAj0BdTH-U3s7bL44fcAGrhAH7C9sKUEmIoMEwbg2TD0k130_assertion description "[Here we report a strong association of two single nucleotide polymorphisms within or in close proximity to the TOR1A 3'UTR, with the lowest p value being 0.000008, in a larger cohort of German and Austrian patients with predominantly focal sporadic dystonia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58591.RAj0BdTH-U3s7bL44fcAGrhAH7C9sKUEmIoMEwbg2TD0k130_provenance.
NP58595.RAqnNpmvHDCNZZtqhjG5UyLZxL4E2CQ5PDqC6beyF_wsA130_assertion description "[Clinical characterization and evaluation of DYT1 gene in Indian primary dystonia patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58595.RAqnNpmvHDCNZZtqhjG5UyLZxL4E2CQ5PDqC6beyF_wsA130_provenance.
NP58598.RAqM3Vp7k_eMqJwNuC0jHa2Coqk3CYhYVh4AiiyV5jfAw130_assertion description "[Transcriptional activity of the MDM2 promoter containing the SNP309 GG genotype was significantly lower than that containing the TT genotype in p53-null lung cancer cells cotransfected with wild-type p53 expression plasmid under mithramycin A treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58598.RAqM3Vp7k_eMqJwNuC0jHa2Coqk3CYhYVh4AiiyV5jfAw130_provenance.
NP58602.RArXkoykI2uQ5w5hiaCBFedlNAbJYGSPL2jexfMPIOnbE130_assertion description "[Four of the variants were found to be weakly associated with lung cancer risk with borderline significance: these were XRCC3 T241M heterozygote odds ratio (OR), 0.89; 95% confidence interval (95% CI), 0.79-0.99 and homozygote OR, 0.84; 95% CI, 0.71-1.00 based on 3,467 cases and 5,021 controls from 8 studies, XPD K751Q (heterozygote OR, 0.99; 95% CI, 0.89-1.10 and homozygote OR, 1.19; 95% CI, 1.02-1.39) based on 6,463 cases and 6,603 controls from 9 studies, and TP53 R72P (heterozygote OR, 1.14; 95% CI, 1.00-1.29 and homozygote OR, 1.20; 95% CI, 1.02-1.42) based on 3,610 cases and 5,293 controls from 6 studies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58602.RArXkoykI2uQ5w5hiaCBFedlNAbJYGSPL2jexfMPIOnbE130_provenance.
NP58603.RAi1SDfsV3yBnz88Gjaof9Fi61wGnfU2_AiAVRKmIEBYA130_assertion description "[In conclusion, our results suggest that the Pro allele at p53 codon 72 is emerging as a low-penetrance susceptibility allele for lung cancer development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58603.RAi1SDfsV3yBnz88Gjaof9Fi61wGnfU2_AiAVRKmIEBYA130_provenance.
NP58604.RAlZFxTTpAO1R-75cDEpT-e7Uvf7ucXSZ4aZCEywuAnBs130_assertion description "[p53 Arg72Pro polymorphism predicts survival outcome in lung cancer patients in Indian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58604.RAlZFxTTpAO1R-75cDEpT-e7Uvf7ucXSZ4aZCEywuAnBs130_provenance.
NP58607.RAoGbXy_Kwvk99uz13NnQ7UEJxvFMBeKxzBZy71x2o798130_assertion description "[This is the second clinical evaluation demonstrating a significant relation between p53 genotype and response to induction therapy in non-small cell lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58607.RAoGbXy_Kwvk99uz13NnQ7UEJxvFMBeKxzBZy71x2o798130_provenance.
NP58612.RAvFoBIGQ4KIYT8yUuGcoARpTM7p7Bq_VLMPyjhX1hNJE130_assertion description "[Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58612.RAvFoBIGQ4KIYT8yUuGcoARpTM7p7Bq_VLMPyjhX1hNJE130_provenance.
NP58614.RAoweXQkuFCXfULl9-9wq6MINdA4wp2LdbTZyTlIFuD0o130_assertion description "[Two authors independently searched the PubMed and EMBASE database from 1966 to January 2010 for studies regarding the association of P53 codon 72 polymorphism with colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58614.RAoweXQkuFCXfULl9-9wq6MINdA4wp2LdbTZyTlIFuD0o130_provenance.
NP58621.RAgVwKkCAT0CYLYfE6iVSC8Pe7mDatZgbTq4syi_QozJY130_assertion description "[The specific aim of this study was to investigate whether the p53 codon 72 polymorphism is associated with individual susceptibility to colorectal cancer in Korean patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58621.RAgVwKkCAT0CYLYfE6iVSC8Pe7mDatZgbTq4syi_QozJY130_provenance.
NP58622.RAtGuZnjy8cDhmWZqIg3zZVy4mgGrctv-guAFILFhu4K0130_assertion description "[Tumour tissues from 118 mCRC patients who underwent FOLFOX treatment from three successive phase II trials were evaluated for mutations in TP53 (exons 5-8) and Kras (codons 12 and 13) and for MSI using PCR-based analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58622.RAtGuZnjy8cDhmWZqIg3zZVy4mgGrctv-guAFILFhu4K0130_provenance.
NP58630.RAgcFv-F3I6pQO9vgZ84CrZzDEq26SrFKsZJKTpBbLmjg130_assertion description "[There was significant association of genetic polymorphisms between gastric cancer and control groups in p53 genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58630.RAgcFv-F3I6pQO9vgZ84CrZzDEq26SrFKsZJKTpBbLmjg130_provenance.
NP58631.RAgD8z-ZagG4aYOc_7aV55A7A65qjL2-s8-atMewgaDks130_assertion description "[ These results suggest that cigarette smoking and alcohol consumption may influence the development of hMLH1-positive gastric cancer. Most dietary factors and polymorphisms of GSTM1, GSTT1, CYP1A1, CYP2E1, ALDH2, and L-myc genes are not independent risk factors for gastric cancer with hypermethylation of the hMLH1 promoter. These data also suggest that there could be two or more different molecular pathways in the development of gastric cancer, perhaps involving tumor suppression mechanisms or DNA mismatch repair.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58631.RAgD8z-ZagG4aYOc_7aV55A7A65qjL2-s8-atMewgaDks130_provenance.
NP58632.RAoEDNL0flgK7Mbjvk7hPztMK6O23V3bG_0kAOi22qIrM130_assertion description "[There was no significant difference in the distribution patterns between gastric ulcer and noncardiac or cardiac cancer or between gastric and duodenal ulcer. These findings may be a reflection of differences in the interaction between p53 codon 72 polymorphism and local factors in the stomach.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58632.RAoEDNL0flgK7Mbjvk7hPztMK6O23V3bG_0kAOi22qIrM130_provenance.
NP58633.RAr_9BqBxFN9VulsVxmCXAdMThDlJFmzSh7pfC6kd8tGQ130_assertion description "[The p53 gene has a polymorphism located at codon 72. which has been associated with higher risk of several types of cancer, including gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58633.RAr_9BqBxFN9VulsVxmCXAdMThDlJFmzSh7pfC6kd8tGQ130_provenance.
NP58639.RAlYqSmDG5RRNFX2Q1Q6sbR8RKIu8DHIrzZ1p7mobTLKk130_assertion description "[Mutations in p53, p53 protein overexpression and breast cancer survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58639.RAlYqSmDG5RRNFX2Q1Q6sbR8RKIu8DHIrzZ1p7mobTLKk130_provenance.
NP58643.RAmEyEozqdJOD9v7yEbB-ItShmwsqL6YGJh2ejeBfU8lc130_assertion description "[NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58643.RAmEyEozqdJOD9v7yEbB-ItShmwsqL6YGJh2ejeBfU8lc130_provenance.
NP58650.RAsLIfxqwY-rCaFL0H4WtbnfDvdJCYqR6OMqtg4tnWsAY130_assertion description "[Screening of TP53 mutations by DHPLC and sequencing in brain tumours from patients with an occupational exposure to pesticides or organic solvents.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58650.RAsLIfxqwY-rCaFL0H4WtbnfDvdJCYqR6OMqtg4tnWsAY130_provenance.
NP58652.RAv8ajLgPm47qht3N3i7UXtI4NPnFt19xGbzc5O2XUNRo130_assertion description "[Although there have been many studies investigating a possible association between p53 codon 72 polymorphism and risk of bladder cancer, the results have been inconsistent.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58652.RAv8ajLgPm47qht3N3i7UXtI4NPnFt19xGbzc5O2XUNRo130_provenance.
NP58656.RApe-k8aDuqO3VjPM6KaOnbPwAsyabaVQxzeL8C_LbGGw130_assertion description "[P53 mutations in urinary bladder cancer patients from Central Poland.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58656.RApe-k8aDuqO3VjPM6KaOnbPwAsyabaVQxzeL8C_LbGGw130_provenance.
NP58657.RAjaDkxdXjTzOPf4vCz6yQ1rfasSHMHcMkdNOgiA5yyys130_assertion description "[p53 single nucleotide polymorphisms and bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58657.RAjaDkxdXjTzOPf4vCz6yQ1rfasSHMHcMkdNOgiA5yyys130_provenance.
NP58658.RAqlwCu0WwyUmEN_833IRjcQtL61CcxuizMw7-S7MPlms130_assertion description "[Role of TP53 Arg72Pro polymorphism in urinary bladder cancer predisposition and predictive impact of proline related genotype in advanced tumors in an ethnic Kashmiri population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58658.RAqlwCu0WwyUmEN_833IRjcQtL61CcxuizMw7-S7MPlms130_provenance.
NP58659.RAnp7YqC0XicSDx3nfmb3iFZHWh7z-xpdv6TkF5Y0IYaY130_assertion description "[The role of TP53 PRO47SER and ARG72PRO single nucleotide polymorphisms in the susceptibility to bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58659.RAnp7YqC0XicSDx3nfmb3iFZHWh7z-xpdv6TkF5Y0IYaY130_provenance.
NP58661.RAnYyI8h0YBjhsuC62Yu6cbxbjHmPKnn2sYkebyxbf4hw130_assertion description "[An association study of the codon 72 polymorphism in the pro-apoptotic gene p53 and Alzheimer's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58661.RAnYyI8h0YBjhsuC62Yu6cbxbjHmPKnn2sYkebyxbf4hw130_provenance.
NP58663.RAt4FN7XEIXetrm6Yux5xscxXqCm8hqauRJ4D4PgWbozY130_assertion description "[Microsatellite instability at selected tetranucleotide repeats is associated with p53 mutations in non-small cell lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58663.RAt4FN7XEIXetrm6Yux5xscxXqCm8hqauRJ4D4PgWbozY130_provenance.
NP58666.RAifoPw1KOgtjC02siSC4cyNVT8QIfw_v_mYX6iFY2iJw130_assertion description "[Association between DNA repair-deficiency and high level of p53 mutations in melanoma of Xeroderma pigmentosum.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58666.RAifoPw1KOgtjC02siSC4cyNVT8QIfw_v_mYX6iFY2iJw130_provenance.
NP58667.RAhqlqjCx-T99G7r7--FZHfDY2ONAewk9TwBpCLjvypX4130_assertion description "[Association of p53 gene mutations with short survival in pancreatic adenocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58667.RAhqlqjCx-T99G7r7--FZHfDY2ONAewk9TwBpCLjvypX4130_provenance.
NP58668.RAuXEYd6I6-JJVoqPzb9cpZ823svI5ExzrykvCGTK6aZM130_assertion description "[In this study, the p53 mutational status was not predictive for responsiveness to platinum-based chemotherapy; but p53 was significantly more frequently mutated in poorly differentiated OCs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58668.RAuXEYd6I6-JJVoqPzb9cpZ823svI5ExzrykvCGTK6aZM130_provenance.
NP58670.RAtlqxskM9oJsu0p9ikTtyALbrM4CoHSEB0v3n5V7Tno4130_assertion description "[We assessed 27 selected polymorphisms based on previously described associations or putative functional effects in 16 key genes from pathways that may influence cellular sensitivity to taxanes (ABCB1, ABCC1, ABCC2, ABCG2, CDKN1A, CYP1B1, CYP2C8, CYP3A4, CYP3A5, MAPT, and TP53) and platinum (ABCC2, ABCG2, ERCC1, ERCC2, GSTP1, MPO, and XRCC1) using polymerase chain reaction and Pyrosequencing in 914 ovarian cancer patients from the Scottish Randomised Trial in Ovarian Cancer phase III trial who were treated at presentation with carboplatin and taxane regimens after cytoreductive surgery.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58670.RAtlqxskM9oJsu0p9ikTtyALbrM4CoHSEB0v3n5V7Tno4130_provenance.
NP58672.RAgb3nav_Yj6fgyUt7QJpt9nBJnyop9TPjmBNBxRDT7NU130_assertion description "[Distribution of p53 codon 72 polymorphisms in ovarian tumour patients and their prognostic significance in ovarian cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58672.RAgb3nav_Yj6fgyUt7QJpt9nBJnyop9TPjmBNBxRDT7NU130_provenance.
NP58677.RAvEttas7sDF7D4I-irTdEA-FhC_wq6gvIps7omjx6XLw130_assertion description "[Immunohistochemical expression of p53 in breast carcinoma is associated with the intron 1 BglII polymorphism of the p53 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58677.RAvEttas7sDF7D4I-irTdEA-FhC_wq6gvIps7omjx6XLw130_provenance.
NP58678.RAmsK5AThmNDg_rfhzxlf0PX8uEdtaF2zOZ8NRfrSzfk4130_assertion description "[The nuclear p53 immunoreaction rate is low in RMS, but p53 expression appears to correlate with poor prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58678.RAmsK5AThmNDg_rfhzxlf0PX8uEdtaF2zOZ8NRfrSzfk4130_provenance.
NP58679.RAgTlICf4f450QPYnfiaFn1bjvJriEWFn245wF3QXgv5k130_assertion description "[Germline mutations of p53 but not p16/CDKN2 or PTEN/MMAC1 tumor suppressor genes predispose to gliomas. The ANOCEF Group. Association des NeuroOncologues d'Expression Franaise.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58679.RAgTlICf4f450QPYnfiaFn1bjvJriEWFn245wF3QXgv5k130_provenance.
NP58680.RAsQsX3SAEDsnrwbHmZgsnI1fJOvsSyH_7hRWYs9EKc0M130_assertion description "[Prognostic value of TP53 Pro47Ser and Arg72Pro single nucleotide polymorphisms and the susceptibility to gliomas in individuals from Southeast Brazil.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58680.RAsQsX3SAEDsnrwbHmZgsnI1fJOvsSyH_7hRWYs9EKc0M130_provenance.
NP58684.RAlohC-sKKvH73kYVHirobEAOJRmw564CNnEqLSpAaC70130_assertion description "[Despite the importance of the p53 pathway in prostate cancer development and progression, little is known about the association of functional single-nucleotide polymorphisms (SNP) in the p53 pathway genes and prostate cancer aggressiveness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58684.RAlohC-sKKvH73kYVHirobEAOJRmw564CNnEqLSpAaC70130_provenance.
NP58686.RArp7GdomEoAOpWrpbhUwN74X4OMTM8MnNDJmjsaYhL3g130_assertion description "[Our study strongly supports the notion that KLF6 and TP53 mutations are not frequent events in prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58686.RArp7GdomEoAOpWrpbhUwN74X4OMTM8MnNDJmjsaYhL3g130_provenance.
NP58689.RAhpkJhNDcUG4SFzlhZ7bmd-OcyTeOuhg0GC7B1Vjqdc4130_assertion description "[A p53 codon 72 polymorphism associated with prostate cancer development and progression in Japanese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58689.RAhpkJhNDcUG4SFzlhZ7bmd-OcyTeOuhg0GC7B1Vjqdc4130_provenance.
NP58690.RAo_rKnj29H0SDvWJmmKS-7UyZBIpW7NU9cu_fLc4KoaA130_assertion description "[The present study demonstrates that population-dependent differences in allele frequencies associated with health disparities provide a valuable framework for the interrogation of complex diseases in all populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58690.RAo_rKnj29H0SDvWJmmKS-7UyZBIpW7NU9cu_fLc4KoaA130_provenance.
NP58691.RApNhdqnCoN9WNTiT6xZpxfWiEVhzpxap6SfvQBokVQHc130_assertion description "[TP53 mutations in exon 7 and exon 8 are factors of tumor progression in PCa. Their contribution to tumor recurrence is more significant than tumor stage and pretherapeutic PSA level.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58691.RApNhdqnCoN9WNTiT6xZpxfWiEVhzpxap6SfvQBokVQHc130_provenance.
NP58695.RAgfGrF51YzYXaUR4xiqLXMe-i_hU6ELXT-KdBfPnlMQ4130_assertion description "[The prevalence of the p53 codon 249 mutation from plasma DNA of hepatocellular carcinoma patients is significantly higher than among controls in South-Western Nigeria and the presence of this mutation is significantly associated with HCC in this region.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58695.RAgfGrF51YzYXaUR4xiqLXMe-i_hU6ELXT-KdBfPnlMQ4130_provenance.
NP58698.RAjr97VcOmTRCbyFXng_Q7RQ-KFBL_k70ryxPzpsaH2To130_assertion description "[The tumor suppressor gene product, in particular tumor suppressor protein p53 (TP53), has been suggested to play a role in post-angioplasty restenosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58698.RAjr97VcOmTRCbyFXng_Q7RQ-KFBL_k70ryxPzpsaH2To130_provenance.
NP58704.RApFhbcCi0BIWb1T-OGoCAUiUjZYaJVS5H-5xKixLibUg130_assertion description "[ In this population, individuals homozygous for the arginine variant of codon 72 of the p53 gene were at increased risk of cervical cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58704.RApFhbcCi0BIWb1T-OGoCAUiUjZYaJVS5H-5xKixLibUg130_provenance.
NP58717.RAq29Ba_U5_xNP91RaZ6ct2nQkiJ7e2XEjQ-sUyQ8yk4w130_assertion description "[ Findings showed that p53 was a poor prognosis biomarker for esophageal cancer gene diagnosis but might benefit to the strategy of treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58717.RAq29Ba_U5_xNP91RaZ6ct2nQkiJ7e2XEjQ-sUyQ8yk4w130_provenance.
NP58722.RAnC3CiCHAQXAnzLahUOSa-jyevCQBV5jYL7d7vfh4riY130_assertion description "[Analysis of ESCC biopsy specimens for p53 gene mutation can identify patients who will not achieve pCR by CRT.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58722.RAnC3CiCHAQXAnzLahUOSa-jyevCQBV5jYL7d7vfh4riY130_provenance.
NP58724.RAr0F_itePceWJb1P5niLOQlwxra-pt61clZ6osdhoDfg130_assertion description "[Investigation of p53 polymorphism for genetic predisposition of keloid and hypertrophic scar.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58724.RAr0F_itePceWJb1P5niLOQlwxra-pt61clZ6osdhoDfg130_provenance.
NP58730.RAn-MGtYKS-i4xYwu9joUldJjLP3KDHk_NxHTb4d9NRB4130_assertion description "[ These data suggest that there is a significant association between the genetic polymorphisms of p53, p21, and specific combinations of the at-risk genotypes of these genes and the risk of developing endometrial cancer in Korean women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58730.RAn-MGtYKS-i4xYwu9joUldJjLP3KDHk_NxHTb4d9NRB4130_provenance.
NP58732.RApWSIetvnWyZS1Qv3ORRUduSDPkshSFhWGZ0zFCgM_7A130_assertion description "[These results suggest that the T allele may be a risk allele, and this XRCC7 polymorphism may be a marker for the susceptibility to glioma. Larger studies are needed to confirm our findings and unravel the underlying mechanisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58732.RApWSIetvnWyZS1Qv3ORRUduSDPkshSFhWGZ0zFCgM_7A130_provenance.
NP58734.RAhwYaqwwYetks0a40a_7CFDqJJNNO4tkiej5Q-jwd2bk130_assertion description "[No significant differences in the frequency of gene sequence variations were found between MS patients and controls. The apoptosis genes studied here therefore appear less likely to be important effector genes in MS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58734.RAhwYaqwwYetks0a40a_7CFDqJJNNO4tkiej5Q-jwd2bk130_provenance.
NP58737.RAv7MvpktO-3Q-mbLQgXtv1AO78FoaUN_dVPS-4qliP7M130_assertion description "[Gene-environment interactions in pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58737.RAv7MvpktO-3Q-mbLQgXtv1AO78FoaUN_dVPS-4qliP7M130_provenance.
NP58742.RAuvLXBbA0btuzjjphIJYiht1VwtToGfCv2goathNAuvk130_assertion description "[Risk estimation for each genotype by an unconditional logistic model demonstrated a possible association between the p73 A4T14 variant and the risk of cervical cancer in our Japanese population (OR = 1.57; 95%CI, 0.99-2.48, P = 0.053).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58742.RAuvLXBbA0btuzjjphIJYiht1VwtToGfCv2goathNAuvk130_provenance.
NP58746.RAiFumX3yHYYoj8iy4isuABVhYe0ZgXv_0kM1-OYrAgEI130_assertion description "[These results suggested that this p73 dinucleotide polymorphism might have had a role to play in the susceptibility of lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58746.RAiFumX3yHYYoj8iy4isuABVhYe0ZgXv_0kM1-OYrAgEI130_provenance.
NP58749.RAk_2Wb34vdYxDgW0CQAG81OUoywzAkJ0NDfsTQHjh7SM130_assertion description "[Association of the responsiveness of advanced non-small cell lung cancer to platinum-based chemotherapy with p53 and p73 polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58749.RAk_2Wb34vdYxDgW0CQAG81OUoywzAkJ0NDfsTQHjh7SM130_provenance.
NP58750.RAvngTVLuBn0_bC-w3Fn1PKbObp9oH3OMvMgFXSAhmRSM130_assertion description "[Lung cancer susceptibility model based on age, family history and genetic variants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58750.RAvngTVLuBn0_bC-w3Fn1PKbObp9oH3OMvMgFXSAhmRSM130_provenance.
NP58753.RAlSGDAdBB1AF1RmvOZiB394ycC5WFAc6wcqKhaV7amnQ130_assertion description "[No association was found between TPH genotypes and suicidal history in schizophrenic patients (P=0.239). The positive finding in this study suggests that the TPH 218A allele is a risk factor for schizophrenic disorders or is in linkage disequilibrium with the putative schizophrenia susceptibility locus in Han Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58753.RAlSGDAdBB1AF1RmvOZiB394ycC5WFAc6wcqKhaV7amnQ130_provenance.
NP58757.RAlTgnpsK7gSomq2qnHnWntmErJdQ_6GykQqpsj_65L_4130_assertion description "[More findings on the consequences of functional polymorphisms for the role of serotonin in the development of brain and serotonergic neurotransmission are needed before more detailed hypotheses regarding susceptibility and outcome in schizophrenia can be formulated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58757.RAlTgnpsK7gSomq2qnHnWntmErJdQ_6GykQqpsj_65L_4130_provenance.
NP58760.RAsdhSNwu2PC4CKfvmgrpeXLuKEOWAuP_G8zclZRmbQVg130_assertion description "[The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58760.RAsdhSNwu2PC4CKfvmgrpeXLuKEOWAuP_G8zclZRmbQVg130_provenance.
NP58761.RAparm8aJHMS5qjY4Jh82auHMZYj3ISNDS_7-dBR5VD1k130_assertion description "[The tryptophan hydroxylase 1 (TPH1) gene and risk of schizophrenia: a moderate-scale case-control study and meta-analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58761.RAparm8aJHMS5qjY4Jh82auHMZYj3ISNDS_7-dBR5VD1k130_provenance.
NP58764.RAkekmTNV0S1FmANWx2BkytzOsFhEgIZIyEvKwb4FoCok130_assertion description "[Temperament and character in mood disorders: influence of DRD4, SERTPR, TPH and MAO-A polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58764.RAkekmTNV0S1FmANWx2BkytzOsFhEgIZIyEvKwb4FoCok130_provenance.
NP58777.RAlv69hscb9rdWpwkjebHv5zLVUbW2G1PfLAAKB7oxg-c130_assertion description "[To investigate the role in suicide of one of the isoforms, TPH1, we examined the association of five single nucleotide polymorphisms (SNPs) in the promoter region and in intron 7 of the TPH1 gene based on a sample from the Chinese population of 810 subjects, of whom 329 had made no suicide attempts (NSA), 297 had made suicide attempts (SA), and 184 were healthy subjects (HS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58777.RAlv69hscb9rdWpwkjebHv5zLVUbW2G1PfLAAKB7oxg-c130_provenance.
NP58780.RAhF5vSP69jREDMJNMzUk5nrMCFwzZqAIZ1NfCodAf_G0130_assertion description "[The most widely studied genetic variations in the TPH gene, which are located in intron 7, yielded conflicting results in individual studies on suicide-related behavior.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58780.RAhF5vSP69jREDMJNMzUk5nrMCFwzZqAIZ1NfCodAf_G0130_provenance.
NP58781.RAhNoYDVkMJGdzpcyDszme8nuoJw30anfEqdqsBQ_1dfw130_assertion description "[Suicide under the influence of alcohol is strongly connected with alcohol dependence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58781.RAhNoYDVkMJGdzpcyDszme8nuoJw30anfEqdqsBQ_1dfw130_provenance.
NP58783.RAr5mVTh43TwA12kVDoRVX6Vy1PzCC5Bx1g4Ci2lnGnhM130_assertion description "[ Polymorphisms in the promoter region may influence the function of the TPH1 gene and further influence the proclivity of alcohol dependence in one ethnic group in Taiwan. The associations between TPH1 genotypes and alcoholism may deserve further investigation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58783.RAr5mVTh43TwA12kVDoRVX6Vy1PzCC5Bx1g4Ci2lnGnhM130_provenance.
NP58786.RAh-Orms2cvZn38NuMwa7UjuvG46CysRQxdC7iqpvuwek130_assertion description "[A case group of males with type 2 alcoholism (N=59) and a control group of healthy males (N=282), both of Croatian origin, were analyzed for the frequency distribution of polymorphisms in 5HT transporter (5HTT-VNTR2, 5HTT-LPR), monoamine oxidase A (MAOA-uVNTR) and B (MAOB-A/G) and tryptophan hydroxylase 1 (TPH1 A218C) and 2 (TPH2 G-703T) genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58786.RAh-Orms2cvZn38NuMwa7UjuvG46CysRQxdC7iqpvuwek130_provenance.
NP58788.RAl1ZXvOjnKtq-dafIP48muePBW1hAFojBHU0Msa50LHE130_assertion description "[One thousand four hundred and twenty-four inpatients affected by bipolar (n=627), major depressive (n=511), schizophrenic (n=210), delusional (n=48) disorder and psychotic disorder not otherwise specified (n=27) (DSM-IV) were included; all patients and 380 controls were typed for the TPH variants using PCR techniques.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58788.RAl1ZXvOjnKtq-dafIP48muePBW1hAFojBHU0Msa50LHE130_provenance.
NP58790.RApncnuiVAp2BeBqgLqObLhVoAWV3iwrvf77I9UCDChpQ130_assertion description "[HTR2A and TPH significantly predicted the depression group, independent of the effects of sex, environmental risk group and their interaction. In addition, there was a trend for an effect of 5HTTLPR, which was significant in female subjects. Furthermore, there was a significant genotype-environmental risk interaction for 5HTTLPR in female subjects only, with the effect being in the same direction as another recent study, reaffirming that an important source of genetic heterogeneity is exposure to environmental risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58790.RApncnuiVAp2BeBqgLqObLhVoAWV3iwrvf77I9UCDChpQ130_provenance.
NP58806.RAhIL45aX2OZIqYG-TU2Z5ZtKblwHnPSQC4R7obytCwtU130_assertion description "[The interaction between TPH2 promoter haplotypes and clinical-demographic risk factors in suicide victims with major psychoses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58806.RAhIL45aX2OZIqYG-TU2Z5ZtKblwHnPSQC4R7obytCwtU130_provenance.
NP58808.RAs6vC4dcQ45AcznG7Jo2CoI21EGlE7QsVbDABM7Tn2U0130_assertion description "[The TPH2 gene and its 5' upstream region variants may be involved in the predisposition to suicide in MDD; however, our findings do not support the role of IABs as mediators.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58808.RAs6vC4dcQ45AcznG7Jo2CoI21EGlE7QsVbDABM7Tn2U0130_provenance.
NP58809.RApjdPpaCfrj7hS6JFSymThsz_QMahUugPIyg9oCqrfU8130_assertion description "[Variation in tryptophan hydroxylase-2 gene is not associated to male completed suicide in Estonian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58809.RApjdPpaCfrj7hS6JFSymThsz_QMahUugPIyg9oCqrfU8130_provenance.
NP58815.RArUCUsQkIoc9--VS85f17hShAneX9FZPeq6AZnW2gDUE130_assertion description "[Here, we investigated the effect of polymorphic variants in the gene of the tryptophan hydroxylase-2 (TPH2), the rate-limiting enzyme of serotonin (5-HT) synthesis in the brain, in children and adolescents with ADHD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58815.RArUCUsQkIoc9--VS85f17hShAneX9FZPeq6AZnW2gDUE130_provenance.
NP58817.RAhPWP9ZThhEjOXpyzYPWtktL7VSuyswmT2XMSKjnm7mc130_assertion description "[A case-control association study of serotonin 1A receptor gene and tryptophan hydroxylase 2 gene in attention deficit hyperactivity disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP58817.RAhPWP9ZThhEjOXpyzYPWtktL7VSuyswmT2XMSKjnm7mc130_provenance.

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