Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence CD4+represents+a+critical+turning+point+that+governs+the+apoptotic+and+survival+programs+in+T+cells%2C+without+modifying+the+physical+association+with+the+TCR-CD3+complex. assertion.
- assertion asSentence Palmitoylation+of+Cys394+and+Cys397+in+the+CVRC+motif+of+CD4+and+CD4%27s+association+with+Lck+are+essential+for+keeping+CD4+highly+concentrated+in+lipid+rafts. assertion.
- assertion asSentence When+undergoing+endocytosis%2C+a+small+fraction+of+CD4+on+the+surface+membranes+of+lymphoblastoid+cells+is+targeted+to+clathrin-coated+pits+where+it+becomes+associated+with+CD71+molecules+that+are+also+targeted+for+endocytosis+into+the+same+pit. assertion.
- assertion asSentence Nef-induced+CD4+down-regulation+is+not+implicated+in+the+Nef%2FCD4+complex+formation+in+the+cellular+context. assertion.
- assertion asSentence CD4%28%2B%29CD25%28%2B%29IL-7Ralpha%28%2B%29+cell+population+represents+a+specific+marker+to+monitor+allospecific+CD4+T+cell+responses+in+blood+and+in+tissues+after+organ+transplantation. assertion.
- assertion asSentence Campath-1H+%28Alemtuzumab%29+is+an+effective+immunodepletion+agent+used+in+renal+transplantation+which+increass+CD4+regulatory+T+cells. assertion.
- assertion asSentence The+mutation+of+lysine-297+and+arginine-340+on+the+alpha-adaptin+specifically+inhibits+the+ability+of+Nef+to+bind+AP-2+and+downregulate+CD4. assertion.
- assertion asSentence Tolerogenic+semimature+dendritic+cells+induce+effector+T-cell+hyporesponsiveness+by+the+activation+of+antigen-specific+CD4%2B+CD25%2B+T-regulatory+cells. assertion.
- assertion asSentence The+specific+affinity+of+gp120+for+alpha%284%29beta%287%29+provides+a+mechanism+for+HIV-1+to+target+activated+cells+that+are+critical+for+efficient+virus+propagation+and+dissemination+following+sexual+transmission. assertion.
- assertion asSentence The+HIV-1+gp120+inner-domain+layers+govern+CD4+triggering+by+participating+in+conformational+transitions+within+gp120+and+regulating+the+interaction+with+gp41. assertion.
- assertion asSentence Recombinant+human+erythropoietin+treatment+normalizes+activation+parameters+of+CD4%28%2B%29+T+lymphocytes+and+their+proliferative+capacity. assertion.
- assertion asSentence Cytomegalovirus-specific+CD4%2B+T-cell+response+is+markedly+increased+in+patients+with+B-cell+chronic+lymphocytic+leukemia. assertion.
- assertion asSentence Demonstrate+an+increase+in+the+proportion+of+CD4%2BCD25highIL-7Ralphahigh+activated+T+cells+in+kidney+transplant+recipients%2C+regardless+of+the+immunosuppressive+regimen. assertion.
- assertion asSentence The+levels+of+inflammatory+factors+are+associated+with+the+variation+of+Foxp3%2BTregs+in+COPD. assertion.
- assertion asSentence CD4-bound+conformation+represents+a+%22ground+state%22+for+the+gp120+core. assertion.
- assertion asSentence CD5+does+not+inhibit+properly+the+BCR-mediated+signaling+in+leukemic+cells. assertion.
- assertion asSentence Hepatitis+C+virus+infection+of+human+T+lymphocytes+is+mediated+by+CD5. assertion.
- assertion asSentence Association+of+T+cell+antigen+CD7+with+type+II+phosphatidylinositol-4+kinase%2C+a+key+component+in+pathways+of+inositol+phosphate+turnover. assertion.
- assertion asSentence Epigenetic+down-regulation+of+CD7+is+associated+with+acute+myeloid+leukemia. assertion.
- assertion asSentence Soluble+HLA-A%2C-B%2C-C+and+-G+molecules+induce+apoptosis+in+T+and+NK+CD8%2B+cells+and+inhibit+cytotoxic+T+cell+activity+through+CD8+ligation. assertion.
- assertion asSentence Establishment+of+a+permanent+CD8%2B+cell+line+from+a+patient+with+leukemic+phase+of+acute+lymphoblastic+lymphoma. assertion.
- assertion asSentence CD8%2BFOXP3%2B+T+cells+play+an+important+role+in+unresponsiveness+related+to+upregulated+interleukin+receptors+on+dendritic+cells. assertion.
- assertion asSentence %5Breview%5D+Coreceptor+CD8alphabeta+contributes+to+the+antigen-recognition+process+by+binding+to+a+largely+invariant+region+of+the+MHCI+molecule+and+by+promoting+intracellular+signaling. assertion.
- assertion asSentence MRP-1%2FCD9+regulates+the+actin+cytoskeleton+by+downregulating+of+the+WAVE2%2C+through+the+Wnt-independent+signal+pathway. assertion.
- assertion asSentence CD9+expression+correlates+with+disease+status+and+survival+of+multiple+myeloma+patients. assertion.
- assertion asSentence CD9%2C+CD81+and+CD63+are+negative+regulators+of+HIV-1-induced+cell-cell+fusion. assertion.
- assertion asSentence Levels+of+CD9+expressed+in+A431+cells+are+much+higher+than+those+expressed+in+KB+cells+and+motility+of+A431+cells+is+also+much+higher+than+that+of+KB+cells. assertion.
- assertion asSentence Decreased+levels+of+CD9+are+strongly+associated+with+an+increased+risk+of+recurrence. assertion.
- assertion asSentence CT+genotype+of+promotor+polymorphism+C159T+in+the+CD14+gene+is+associated+with+lower+prevalence+of+atopic+dermatitis+and+lower+IL-13+production. assertion.
- assertion asSentence Significantly+elevated+serum+concentrations+of+LBP+and+sCD14+are+found+in+severe+sepsis+patients. assertion.
- assertion asSentence PI3+kinase+effectors+PKB+and+PKC%28zeta%29+are+also+activated+by+PI3+kinase+in+a+CD14+dependent+manner+in+lipopolysaccharides+stimulated+human+peripheral+blood+mononuclear+cells. assertion.
- assertion asSentence CD14%2F-159+SNP+is+associated+with+atopic+diseases+in+Chinese+Han+ethnic+group+children. assertion.
- assertion asSentence A+polymorphism+in+the+CD14+gene+%28CD14%2F-1721%29+modifies+the+inverse+association+of+early+farm+milk+consumption+on+allergic+diseases+in+children+in+2+independent+rural+populations%2C+independent+of+being+a+farm+child. assertion.
- assertion asSentence Upregulated+ex+vivo+expression+of+stress-responsive+inflammatory+pathway+genes+by+LPS-challenged+CD14%28%2B%29+monocytes+in+frail+older+adults. assertion.
- assertion asSentence CD14+gene+promoter+C-159T+polymorphism+is+significantly+correlated+with+juvenile+idiopathic+arthritis+in+the+Chinese+Han+population. assertion.
- assertion asSentence CD14+promoter+polymorphism+%28-+159C--%3Et%29+is+not+associated+with+myocardial+infarction+or+coronary+artery+disease+in+patients+with+assumed+high+genetic+risk. assertion.
- assertion asSentence Genetic+polymorphisms+in+the+promoter+region+of+the+CD14-receptor+gene+are+associated+with+a+higher+risk+of+having+an+acute+coronary+syndrome+as+first+the+manifestation+of+coronary+artery+disease. assertion.
- assertion asSentence In+glioblastoma+patients%2C+the+major+population+of+altered+CD14-positiveHLA-DRlo%2Fnegative+monocytes+have+a+phenotype+distinct+from+classical+myeloid+suppressor+cells. assertion.
- assertion asSentence GPx-1+modulates+LPS-mediated+up-regulation+of+ICAM-1+and+VCAM-1+mRNA+and+protein+in+endothelial+cells%2C+in+part%2C+by+altering+CD14-mediated+effects. assertion.
- assertion asSentence sMD-2+and+sCD14+inhibit+the+growth+of+both+Gram-positive+and+Gram-negative+bacteria. assertion.
- assertion asSentence IL-33%2C+acting+specifically+through+ST2%2C+regulates+the+formation+of+osteoclasts+from+human+peripheral+blood+CD14%2B+monocytes+and+bone+resorption. assertion.
- assertion asSentence PBMC+from+asthmatic+children+with+the+TT+genotype+at+position+-159+of+the+CD14+gene+make+more+IgE+than+those+with+the+CC+genotype+following+LPS+stimulation+because+of+increased+germline+transcription+and+have+an+augmented+Th2+cytokine+profile. assertion.
- assertion asSentence Monocytes+help+in+the+survival+of+chronic+lymphocytic+leukemia+cells+by+secreting+soluble+CD14. assertion.
- assertion asSentence CD14%28dim%29+cells+are+bona+fide+monocytes+involved+in+the+innate+local+surveillance+of+tissues+and+the+pathogenesis+of+autoimmune+diseases. assertion.
- assertion asSentence Low+CD14+is+associated+with+Crohn%27s+disease. assertion.
- assertion asSentence Transgenic+CD14+is+a+critical+regulator+of+the+microglial+inflammatory+response+that+acts+to+modulate+amyloid+beta+protein.+deposition. assertion.
- assertion asSentence CD14-260C%2FT+polymorphism+can+contribute+to+B-ALL+%28Precursor+B-Cell+Lymphoblastic+Leukemia-Lymphoma%29+risk+in+a+Chinese+population. assertion.
- assertion asSentence In+patients+with+stable+coronary+artery+disease+the+CRP+1444TT+and+CD14+260TT+variants+are+associated+with+larger+coronary+plaque+volume+independently+of+concomitant+cardiovascular+risk+factors. assertion.
- assertion asSentence CD81+up-regulation+can+increase+the+risk+of+hepatitis+C+virus%2C+particularly+in+HIV-infected+subjects. assertion.
- assertion asSentence CD81+gene+defect+in+humans+disrupts+CD19+complex+formation+and+leads+to+antibody+deficiency. assertion.
- assertion asSentence The+C-terminal+domain+is+important+for+the+function+of+HTm4+in+cell+cycle+regulation. assertion.
- assertion asSentence High+HTm4+is+associated+with+neoplasms. assertion.
- assertion asSentence CD70%2FCD27+interaction+provides+a+critical+stimulus+for+expanding+effector+T+cells%2C+enhancing+their+cytotoxic+activity+and+improving+the+antileukemic+effector+response. assertion.
- assertion asSentence A+double-negative+%28IgD-CD27-%29+B+cell+population+is+increased+in+the+peripheral+blood+of+elderly+people. assertion.
- assertion asSentence CD27+signalling+does+influence+T%28H%29+cell+differentiation. assertion.
- assertion asSentence The+phosphatidylinositol+3-hydroxykinase-protein+kinase+B+pathway+links+CD28+to+cell+cycle+progression+in+primary+T+cells. assertion.
- assertion asSentence Tyrosine+200+of+CD28+is+required+for+efficient+expression+of+HIV-1+transcription+in+activated+T+cells. assertion.
- assertion asSentence Polymorphism+of+CD28+%28CD28-I3+%2B+17%29+does+not+affect+the+risk+of+developing+multiple+sclerosis+and+has+no+influence+on+the+course+and+progression+of+disease. assertion.
- assertion asSentence CD28+costimulation+activates+AKT+to+phosphorylate+NF90+at+Ser647+and+phosphorylation+triggers+NF90+to+relocate+to+the+cytoplasm+and+stabilize+IL-2+mRNA. assertion.
- assertion asSentence The+CD28+gene+c.534%2B17T%3E+polymorphism+does+not+represent+an+important+risk+factor+for+diabetes+mellitus+type+2+in+a+group+of+the+Turkish+population. assertion.
- assertion asSentence Genetic+variation+in+CD28+gene+is+associated+with+acute+rejection+of+liver+transplantation. assertion.
- assertion asSentence On+the+biological+relevance+of+MHC+class+II+and+B7+expression+by+tumour+cells+in+melanoma+metastases. assertion.
- assertion asSentence CD80+transfection+can+lower+malignant+phenotype+of+hepatocarcinoma+cells+and+has+a+down-regulatory+effect+to+activated+T+cells+in+vitro. assertion.
- assertion asSentence Interaction+of+human+PD-L1+and+B7-1. assertion.
- assertion asSentence B+cells+with+reduced+B7+expression+reduce+the+antigen+%28Ag%29+specific+t-cell+proliferation+in+vitro. assertion.
- assertion asSentence Thalidomide+can+up-regulate+the+expression+of+B7-1+molecules+on+myeloma+cells. assertion.
- assertion asSentence Upregulation+in+the+colonic+mucosa+of+patients+with+ulcerative+colitis. assertion.
- assertion asSentence NF-kappaB+signal+plays+a+key+role+in+LIGHT-mediated+upregulation+of+CD86+expression. assertion.
- assertion asSentence The+%2B1057G%2FA+polymorphism+of+the+CD86+gene+is+associated+with+increased+susceptibility+to+Ewing%27s+sarcoma. assertion.
- assertion asSentence Serum+levels+after+kidney+transplantation+predicts+acute+rejection+episodes. assertion.
- assertion asSentence Soluble+CD30+and+Hepatocyte+growth+factor+as+predictive+markers+of+antibody-mediated+rejection+of+the+kidney+allograft. assertion.
- assertion asSentence Single+nucleotide+polymorphism+in+TNFSF8+gene+is+associated+with+bone+disease+in+myeloma. assertion.
- assertion asSentence Common+variants+at+MS4A4%2FMS4A6E%2C+CD2AP%2C+CD33+and+EPHA1+are+associated+with+late-onset+Alzheimer%27s+disease. assertion.
- assertion asSentence CD34+is+a+surface+receptor+molecule+that+is+modulated+by+receptor-mediated+endocytosis. assertion.
- assertion asSentence Immature+CD34%2BCD19-+progenitor%2Fstem+cells+in+TEL%2FAML1-positive+acute+lymphoblastic+leukemia+are+genetically+and+functionally+normal. assertion.
- assertion asSentence No+siatistically+significant+value+in+assocation+with+survival+or+event-free+survival+in+head+and+neck+squamous+cell+carcinoma. assertion.
- assertion asSentence High+CD34+expression+is+associated+with+gallbladder+carcinoma. assertion.
- assertion asSentence Human+CD34%28%2B%29+cells+secrete+exosomes+that+have+independent+angiogenic+activity+both+in+vitro+and+in+vivo. assertion.
- assertion asSentence Promoter+polymorphism+in+CD36+is+associated+with+atherogenesis+is+french+population. assertion.
- assertion asSentence CD36+mRNA+decreased+in+idiopathic+pulmonary+fibrosis. assertion.
- assertion asSentence In+obese+humans+the+FAT%2FCD36+protein+content+in+skeletal+muscle+is+dynamically+regulated+by+insulin+in+vivo+on+the+short+term. assertion.
- assertion asSentence Specific+binding+of+hypochloride-oxidized+HDL+to+platelet+CD36+is+essential+for+the+proinflammatory+and+procoagulant+effects+of+hyp-OxHDL. assertion.
- assertion asSentence Subcellular+trafficking+of+the+substrate+transporters+GLUT4+and+CD36+in+cardiomyocytes. assertion.
- assertion asSentence The+presence+of+the+c.1264+T%3EG+mutation+that+leads+to+CD36+deficiency+is+closely+associated+with+reduced+IgG+production+and+higher+malaria+incidence. assertion.
- assertion asSentence SR-BI+is+a+phagocytosis-inducing+PS+receptor+of+Sertoli+cells. assertion.
- assertion asSentence Transcriptional+activation+of+SR-BI+is+stimulated+by+peroxisome+proliferator-activated+receptor+gamma+and+hepatocyte+nuclear+factor+4alpha. assertion.
- assertion asSentence SR-BI+prevents+NO-induced+cytotoxicity+when+transected+into+CHO+cells. assertion.
- assertion asSentence Mek1%2F2+inhibition+enhances+the+PPARalpha-dependent+degradation+of+SR-BI+in+hepatocytes. assertion.
- assertion asSentence High+density+lipoprotein+endocytosis+by+scavenger+receptor+SR-BII+is+clathrin-dependent+and+requires+a+carboxyl-terminal+dileucine+motif. assertion.
- assertion asSentence CD37+is+important+for+dectin-1+stabilization+in+APC+membranes+and+controls+dectin-1-mediated+IL-6+production. assertion.
- assertion asSentence miR-140-3p+modulates+CD38+expression+in+human+airway+smooth+muscle+cells+through+direct+binding+to+the+CD38+untranslated+region+and+indirect+mechanisms+involving+activation+of+p38+MAPK+and+NF-kappaB. assertion.
- assertion asSentence Distinct+roles+for+CD39+and+P2-purinergic+signaling+in+both+tissue+remodeling+and+fibrogenesis+with+respect+to+human+pancreatic+diseases. assertion.
- assertion asSentence CD39+is+expressed+at+high+levels+in+clinical+inflammatory+bowel+disease+tissues. assertion.
- assertion asSentence NTPDase2+preferentially+hydrolyzes+nucleoside+triphosphates. assertion.
- assertion asSentence CD40%3ACD40L+interactions+in+X-linked+and+non-X-linked+hyper-IgM+syndromes. assertion.
- assertion asSentence Short-circuiting+long-lived+humoral+immunity+by+the+heightened+engagement+of+CD40. assertion.
- assertion asSentence CD40+induces+human+multiple+myeloma+cell+migration+via+phosphatidylinositol+3-kinase%2FAKT%2FNF-kappa+B+signaling. assertion.
- assertion asSentence Interleukin-10+induction+of+endothelial+nitric-oxide+synthase+expression+attenuates+CD40-mediated+interleukin-12+synthesis+in+human+endothelial+cells. assertion.
- assertion asSentence CD40%2FCD40L+signaling+contributes+to+inflammatory+and+prothrombogenic+responses+and+brain+infarction+induced+by+middle+cerebral+artery+occlusion+and+reperfusion. assertion.
- assertion asSentence Single+cytidine%2Fthymine+nucleotide+polymorphism+has+no+association+with+disease+susceptibility+or+disease+course+in+multiple+sclerosis. assertion.