Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence There+is+an+association+between+the+presence+of+HPV-16+in+epithelial+dysplasia+and+the+occurrence+of+p16%28CDKN2A%29+methylation. assertion.
- assertion asSentence Shelterin+dysfunction+and+ensuing+upregulation+of+INK4a+promote+accelerated+aging+of+HIV-1-specific+T+cells+during+progressive+HIV-1+infection. assertion.
- assertion asSentence Inactivation+of+p16%2FCDKN2+and+p15%2FMTS2+is+associated+with+prognosis+and+response+to+chemotherapy+in+ovarian+cancer. assertion.
- assertion asSentence Activation+of+ERK+together+with+its+downstream+transcriptional+machinery+mediated+p15%28INK4b%29+expression+that+led+to+HepG2+growth+inhibition+triggered+by+TPA+and+Saikosaponin+a. assertion.
- assertion asSentence Inactivation+of+CDKN2A+and+B+genes+constitute+an+important+step+in+chordoma+development. assertion.
- assertion asSentence As2O3+treatment+caused+demethylation+associated+with+an+increase+in+mRNA+levels+of+the+CDKN2B+and+CDKN2A+genes. assertion.
- assertion asSentence Strategies+to+re-express+epigenetically+silenced+p15%28INK4b%29+and+p21%28WAF1%29+genes+in+acute+myeloid+leukemia. assertion.
- assertion asSentence Expression+of+a+novel%2C+circular+ANRIL+isoforms+%28cANRIL%29+is+correlated+with+INK4%2FARF+transcription+and+atherosclerosis+risk. assertion.
- assertion asSentence CDKN2B+is+significantly+associated+with+open-angle+glaucoma. assertion.
- assertion asSentence Increased+methylation+of+CDKN2B+gene+is+associated+with+myelodysplastic+syndromes+and+acute+myeloid+leukemia. assertion.
- assertion asSentence Overexpression+of+CDR1+and+CDR2+genes+are+associated+with+fluconazole+resistance+in+Candida+albicans+with+G487T+and+T916C+mutations. assertion.
- assertion asSentence Cdx1+is+not+an+oncogene+in+normal+intestinal+epithelium. assertion.
- assertion asSentence RNA+interference+of+CDX1+and+CDX2+and+chromatin+immunoprecipitation+in+colon+cancer+cells+revealed+that+MS4A12+transcript+and+protein+expression+is+essentially+dependent+on+the+presence+of+endogenous+CDX2. assertion.
- assertion asSentence Expression+of+CDX1+and+CDX4+is+not+correlated+with+the+pathogenesis+and+relapse+of+adult+ALL. assertion.
- assertion asSentence Bile+acids+induce+overexpression+of+homeobox+gene+CDX-2+in+human+Barrett%27s+esophageal+mucosa+and+adenocarcinoma+cell+line. assertion.
- assertion asSentence Significant+correlations+sre+found+between+claudin-2+and+Cdx2+protein+expression+in+dysplasia+and+intestine-type+adenocarcinoma. assertion.
- assertion asSentence Loss+of+CDX2+and+CK20+is+more+frequently+encountered+in+mismatch+repair-deficient+colorectal+cancer. assertion.
- assertion asSentence Cdx2+regulates+E-cadherin+function+indirectly+by+disrupting+receptor+tyrosine+kinase+activity+and+enhancing+E-cadherin+trafficking+to+the+cell+membrane+compartment. assertion.
- assertion asSentence A+significant+relation+of+PDX1+and+CDX2+expressions+among+phenotypic+classification+of+gastric+carcinomas+reveals+an+idea+about+similar+functions+for+PDX1+and+CDX2+in+the+evolution+of+gastric+carcinoma. assertion.
- assertion asSentence Enhanced+induction+of+dendritic+cell+maturation+and+HLA-A%2A0201-restricted+CEA-specific+CD8%28%2B%29+CTL+response+by+exosomes+derived+from+IL-18+gene-modified+CEA-positive+tumor+cells. assertion.
- assertion asSentence High+CEA+serum+level+is+a+risk+factor+for+brain+metastasis+development+and+is+associated+with+poor+prognosis+in+patients+with+advanced+NSCLC. assertion.
- assertion asSentence High+carcinoembryonic+antigen+in+serum+is+associated+with+colorectal+cancer. assertion.
- assertion asSentence High+Carcinoembryonic+Antigen+levels+and+low+selenium+levels+are+associated+with+gastric+cancer. assertion.
- assertion asSentence Increasing+carcinoembryonic+antigen+is+associated+with+colorectal+cancer. assertion.
- assertion asSentence The+histological+types+of+breast+cancer+are+not+significantly+related+to+elevated+serum+levels+of+CEA+and%2For+CA+15-3. assertion.
- assertion asSentence High+levels+of+carcinogenic+embryonic+antigen+are+associated+with+advanced+stage+of+diseases+of+pancreas+and+liver. assertion.
- assertion asSentence Down-regulation+and+antiproliferative+role+of+C%2FEBPalpha+in+lung+cancer. assertion.
- assertion asSentence C%2FEBPbeta+enhancer%2C+prolactin%2C+significantly+induced+extracellular+superoxide+dismutase+mRNA+and+protein. assertion.
- assertion asSentence Phosphorylation-dependent+switch+of+biological+functions+of+C%2FEBPalpha+promotes+liver+proliferation. assertion.
- assertion asSentence Ubc9+is+an+important+C%2FEBPalphap30+target+through+which+C%2FEBPalphap30+enhances+the+sumoylation+of+C%2FEBPalphap42+to+inhibit+granulocytic+differentiation. assertion.
- assertion asSentence Epigenetic+alterations+of+C%2FEBP+alpha+are+a+frequent+event+in+acute+myeloid+leukemia. assertion.
- assertion asSentence HCMV+UL84+interacted+with+several+regions+of+oriLyt+that+contain+C%2FEBPalpha+transcription+factor+binding+sites. assertion.
- assertion asSentence Acute+myeloid+leukemia+with+biallelic+CEBPA+gene+mutations+and+normal+karyotype+represents+a+distinct+genetic+entity+associated+with+a+favorable+clinical+outcome. assertion.
- assertion asSentence C%2FEBPalpha+is+up-regulated+in+a+subset+of+hepatocellular+carcinomas+and+has+growth-promoting+activities. assertion.
- assertion asSentence CCAAT%2Fenhancer+binding+protein-beta+is+a+mediator+ofkeratinocyte+survival+and+skin+tumorigenesis+involving+oncogenic+Ras+signaling. assertion.
- assertion asSentence Isoform+LAP%2A+is+the+primary+isoform+of+C%2FEBP+beta+that+regulates%2C+through+a+redox+switch%2C+the+LPS-induced+expression+of+the+IL-6+gene. assertion.
- assertion asSentence Mechanisms+of+MDR1+activation+by+C%2FEBPbeta+include+C%2FEBPbeta+binding+of+the+chromatin+of+the+MDR1+gene+and+interactions+of+C%2FEBPbeta+with+the+Y+box+and+Y+box-associated+proteins. assertion.
- assertion asSentence Defective+thermoregulation+owing+to+the+lack+of+C%2FEBPbeta+is+associated+with+the+reduced+capacity+to+supply+fatty+acids+as+fuels+to+sustain+brown+fat+thermogenesis. assertion.
- assertion asSentence C%2FEBP-beta+participates+in+insulin-responsive+expression+of+the+F7+gene. assertion.
- assertion asSentence C%2FEBPbeta+directly+binds+to+the+MMP-13+promoter+region+and+stimulates+the+expression+of+MMP-13+in+chondrocytes+in+inflammatory+arthritis. assertion.
- assertion asSentence Both+CBF1+and+C%2FEBP-beta+bind+the+CR2+promoter+in+B+cells+raising+the+possibility+that+these+factors+facilitate+or+respond+to+alterations+in+chromatin+structure+to+control+the+timing+and%2For+level+of+CR2+transcription. assertion.
- assertion asSentence HSD17B10+is+regulated+by+several+isoforms+of+C%2FEBP-beta+in+HepG2+cells. assertion.
- assertion asSentence The+tumor+suppression+in+SMMC-7721+by+C%2FEBPbeta+3%27UTR+RNA+is+due+to+the+inhibition+of+protein+kinase+Cepsilon+activity+through+direct+physical+interaction+between+C%2FEBPbeta+3%27UTR+RNA+and+protein+kinase+Cepsilon. assertion.
- assertion asSentence C%2FEBPbeta+mediates+the+activation+of+EBV+lytic+gene+expression+associated+with+bortezomib+and+another+UPR+inducer. assertion.
- assertion asSentence Knockdown+of+C%2FEBPbeta+isoforms+blocks+activation+of+human+papillomavirus+%28HPV%29+late+gene+expression+from+complete+viral+genomes+upon+differentiation. assertion.
- assertion asSentence The+requirement+for+C%2FEBP+epsilon+in+mediating+BPI+gene+expression+in+myeloid+cells+in+vitro+and+in+vivo. assertion.
- assertion asSentence C%2FEBP+epsilon+is+a+critical+transcription+factor+for+tumor+necrosis+factor+alpha-induced+up-regulation+of+phospholipid+hydroperoxide+glutathione+peroxidase+%28PHGPx%29+expression+in+non-differentiated+HL60+cells. assertion.
- assertion asSentence C%2FEBPgamma+positively+regulates+wound+repair+both+in+vitro+and+in+vivo%2C+at+least+in+part%2C+by+affecting+EGFR+signaling. assertion.
- assertion asSentence Binding+of+human+milk+to+pathogen+receptor+DC-SIGN+varies+with+bile+salt-stimulated+lipase+%28BSSL%29+gene+polymorphism. assertion.
- assertion asSentence BSSL+and+PLRP2+hydrolyzed+triglycerides+%28TG%29+to+free+FA+and+glycerol. assertion.
- assertion asSentence Phosphorylation+of+CENP-A+on+Ser-7+by+Aurora-A+in+prophase+is+essential+for+kinetochore+function. assertion.
- assertion asSentence Two+neocentromeres+formed+in+chromosome+8q21+with+a+unique+DNA+and+CENP-A+chromatin+configuration. assertion.
- assertion asSentence CENP-C+and+CENP-H+co-localize+to+the+CENP-A+chromatin+domain. assertion.
- assertion asSentence Direct+binding+of+Cenp-C+to+the+Mis12+complex+joins+the+inner+and+outer+kinetochore. assertion.
- assertion asSentence Microtubule+capture+by+CENPE+silences+BubR1-dependent+mitotic+checkpoint+signaling. assertion.
- assertion asSentence SEPT7+forms+a+link+between+kinetochore+distribution+of+CENP-E+and+the+mitotic+spindle+checkpoint. assertion.
- assertion asSentence Targeting+of+CENP-E+and+BubR1+to+the+kinetochores+and+the+interaction+between+CENP-E+and+BubR1+are+significantly+reduced+in+EpoB-resistant+A549+cell+line%2C+compared+to+A549+cells. assertion.
- assertion asSentence SKAP+cooperates+with+CENP-E+to+orchestrate+dynamic+kinetochore-microtubule+interaction+for+faithful+chromosome+segregation. assertion.
- assertion asSentence Altered+expression+is+associated+with+therapy+failure+and+death+in+patients+with+multiple+types+of+cancer. assertion.
- assertion asSentence Centrin+2+stimulates+nucleotide+excision+repair+by+interacting+with+XPC. assertion.
- assertion asSentence Association+between+HDL-cholesterol+and+the+Taq1B+polymorphism+in+the+cholesterol+ester+transfer+protein+gene+in+obese+women. assertion.
- assertion asSentence D442G+mutation+is+common+in+Korean+postmenopausal+women+and+it+is+associated+with+increased+plasma+HDL+cholesterol+level. assertion.
- assertion asSentence CEPT+gene+locus+have+an+additional+and+interactive+influence+on+plasma+lipid+and+lipoprotein+levels+in+children. assertion.
- assertion asSentence CETP+localizes+B+cells+in+germinal+centres%2C+a+proportion+of+post-germinal+centre+B+cells+and+their+neoplastic+counterparts. assertion.
- assertion asSentence An+association+between+the+CETP+TaqIB+polymorphism+and+atrial+fibrillation. assertion.
- assertion asSentence TaqIB+polymorphism+is+associated+with+plasma+HDL+cholesterol+levels+and+parental+history+of+cardiovascular+disease+in+Taiwan. assertion.
- assertion asSentence Mineralocorticoid+and+blood+pressure+responsiveness+to+dietary+salt+intake+are+not+significantly+related+to+physiological+interindividual+differences+in+plasma+CETP. assertion.
- assertion asSentence Torcetrapib+differentially+modulates+the+biological+activities+of+HDL2+and+HDL3+particles+in+the+reverse+cholesterol+transport+pathway. assertion.
- assertion asSentence Single-nucleotide+polymorphisms+in+CETP+is+associated+with+chronic+kidney+disease+in+Type+2+diabetes. assertion.
- assertion asSentence CETP+modulator+dalcetrapib+specifically+increased+markers+of+cholesterol+absorption+in+healthy+subjects. assertion.
- assertion asSentence A+strong+association+of+CETP+rs3764261+with+high-density+lipoprotein+cholesterol. assertion.
- assertion asSentence Oxidant-induced+apoptosis+is+mediated+by+oxidation+of+CFL. assertion.
- assertion asSentence These+measurements+support+a+cofilin-severing+mechanism+in+which+mechanical+asymmetry+promotes+local+stress+accumulation+and+fragmentation+at+boundaries+of+bare+and+cofilin-decorated+segments%2C+analogous+to+failure+of+some+nonprotein+materials. assertion.
- assertion asSentence Protein+kinase+C+epsilon-dependent+regulation+of+cystic+fibrosis+transmembrane+regulator+involves+binding+to+a+receptor+for+activated+C+kinase+%28RACK1%29+and+RACK1+binding+to+Na%2B%2FH%2B+exchange+regulatory+factor. assertion.
- assertion asSentence Regulation+of+channel+gating+by+AMP-activated+protein+kinase+modulates+cystic+fibrosis+transmembrane+conductance+regulator+activity+in+lung+submucosal+cells. assertion.
- assertion asSentence Equilibrative+nucleoside+transporters+%28hENT1%2C+hENT2%29+together+with+adenosine+kinase+and+5%27-nucleotidase+play+a+crucial+role+in+the+regulation+of+CFTR+through+an+adenosine-dependent+pathway+in+human+airway+epithelia. assertion.
- assertion asSentence Compacted+DNA+nanoparticles+administered+to+the+nasal+mucosa+of+cystic+fibrosis+subjects+are+safe+and+demonstrate+partial+to+complete+CFTR+reconstitution. assertion.
- assertion asSentence Cystic+fibrosis+%28CF%29+is+a+recessively+inherited+condition+caused+by+mutation+of+the+cystic+fibrosis+transmembrane+conductance+regulator+%28CFTR%29+gene. assertion.
- assertion asSentence Cystic+fibrosis+with+homozygous+CFTR+I1234V+mutation+is+associated+with+pancreatic+sufficiency. assertion.
- assertion asSentence Structurally+and+functionally+intact+CFTR+NBD-1+in+activated+CFTR+can+regulate+mENaC+surface+expression+independent+of+Cl%28-%29+transport+in+Xenopus+oocytes. assertion.
- assertion asSentence Modulation+of+the+expression+level+of+CFTR+protein+partners%2C+like+NHE-RF1%2C+can+rescue+sequence-deleted+CFTR+activity. assertion.
- assertion asSentence Cystic+fibrosis+transmembrane+conductance+regulator+is+vital+to+sperm+fertilizing+capacity+and+male+fertility. assertion.
- assertion asSentence The+50%25+reduction+in+the+CF+transmembrane+conductance+regulator+protein+in+heterozygotes+is+insufficient+to+cause+platelet+activation. assertion.
- assertion asSentence Interference+with+Hook2+function+alters+CFTR+aggresome+formation. assertion.
- assertion asSentence Pre-mRNA+secondary+structure+plays+a+major+role+on+donor-site+usage+and+splicing+efficiency+in+CFTR+pseudoexon+inclusion+events. assertion.
- assertion asSentence A+TG15+T5+gene+variant+in+trans+with+a+cystic+fibrosis+causing+mutation+in+monozygotic+twins. assertion.
- assertion asSentence The+multidrug+resistance+protein+4+%28MRP4%29%2C+a+cAMP+transporter%2C+functionally+and+physically+associates+with+CFTR. assertion.
- assertion asSentence Genetic+modifiers+%28i.e.+genes+other+than+CFTR%29+are+the+primary+cause+of+diabetes+in+cystic+fibrosis. assertion.
- assertion asSentence Mutations+within+the+CFTR+gene+are+assiciated+with+congenital+absence+of+vas+deferens. assertion.
- assertion asSentence Substance+P+stimulates+human+airway+submucosal+gland+secretion+mainly+via+a+CFTR-dependent+process. assertion.
- assertion asSentence AMP-activated+protein+kinase+phosphorylation+of+the+R+domain+inhibits+PKA+stimulation+of+CFTR. assertion.
- assertion asSentence Lck+of+the+CFTR+plays+an+intrinsic+role+in+skeletal+muscle+atrophy+and+dysfunction+in+cystic+fibrosis. assertion.
- assertion asSentence The+frameshift+mutation+3905insT+is+one+of+the+most+common+CFTR+mutations+in+the+Swiss+population+with+cystic+fibrosis. assertion.
- assertion asSentence Curcumin+cross-links+CFTR+and+potentiates+CFTR+channel+activity+in+microsomes+and+in+intact+cells. assertion.
- assertion asSentence Direct+sensing+of+intracellular+pH+by+the+cystic+fibrosis+transmembrane+conductance+regulator+%28CFTR%29+Cl-+channel. assertion.
- assertion asSentence Exon+copy+number+variants+of+CFTR+gene+is+not+a+major+mutation+that+gives+rise+to+cystic+fibrosis+in+Black+and+colored+southern+South+Africans. assertion.
- assertion asSentence A+dynamic+increase+in+the+cystic+fibrosis+transmembrane+conductance+regulator+bicarbonate+permeability+by+intracellular+chloride+concentration-sensitive+mechanisms+plays+a+pivotal+role+in+pancreatic+bicarbonate+secretion. assertion.
- assertion asSentence Specific+CFTR+genotypes+are+significantly+associated+with+pancreatitis. assertion.
- assertion asSentence Transcription+defects+in+CFTR+are+associated+with+cystic+fibrosis+phenotype. assertion.
- assertion asSentence Common+CFTR+haplotypes+modulate+ICP+and+CBAVD+susceptibility+alone+and+in+heterozygous+CFTR. assertion.