Nanopublications LDF server

Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }

• NP123138.RAuIQ5VDYWUoKNRgeIZFrKlviUB1OE2jCZ0p3MAUSEQXo130_assertion description "[Corin I555 (P568) allele represents a cardiac hypertrophy-sensitizing genetic locus in systemic hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123138.RAuIQ5VDYWUoKNRgeIZFrKlviUB1OE2jCZ0p3MAUSEQXo130_provenance.
• NP123140.RAuuUDBm0ivJBsxmlBMTCYMeuwNTVcQmEOP1NiHZId4to130_assertion description "[roles of Thr418Ser polymorphism of the CLCNKB gene and Arg904Gln polymorphism in the TSC gene on essential hypertension need to be explored in other ethnic groups ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123140.RAuuUDBm0ivJBsxmlBMTCYMeuwNTVcQmEOP1NiHZId4to130_provenance.
• NP123144.RAkLDe_XvK3937c2LzIhRq4uivz3lV0e8Bj1vMOWheJ10130_assertion description "[High job stress and polymorphism of beta2-AR-16 have an interactive effect on the prevalence of hypertension in Chinese male workerss.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123144.RAkLDe_XvK3937c2LzIhRq4uivz3lV0e8Bj1vMOWheJ10130_provenance.
• NP123145.RAokL8c1ZYgfR6hR096-XuNWP9d-_UKjJ5Sbj65mSZLMg130_assertion description "[Variants at the ADRB2 locus may play a role in the pathophysiology of hypertension specifically in the Yi minority group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123145.RAokL8c1ZYgfR6hR096-XuNWP9d-_UKjJ5Sbj65mSZLMg130_provenance.
• NP123150.RAq8JM9cb0T7vst5cMIcuJxaW8gtXnYimHUFmEBgoMYjc130_assertion description "[ADRB2 R16G polymorphism may play an important role in diastolic blood pressure response to benazepril treatment in hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123150.RAq8JM9cb0T7vst5cMIcuJxaW8gtXnYimHUFmEBgoMYjc130_provenance.
• NP123152.RAnB0eojm6tbpTl4nSYxZ8NMsHwObhQcVP9aax6bC7WYY130_assertion description "[variants at the B2AR locus may play a role in the pathophysiology of hypertension in a Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123152.RAnB0eojm6tbpTl4nSYxZ8NMsHwObhQcVP9aax6bC7WYY130_provenance.
• NP123155.RAiYpDhhQq8E2tpzkqMKYbOmW0UOxhdfPWvzbwhTCSIeU130_assertion description "[Statistically significant positive correlation was between changes in blood pressure and changes in leptin levels/may play role in pathophysiology of obese hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123155.RAiYpDhhQq8E2tpzkqMKYbOmW0UOxhdfPWvzbwhTCSIeU130_provenance.
• NP123163.RAsRFokZbfklR6FRiU1Vx79N4Yz_ZdoeiesCD-1Ad6WHQ130_assertion description "[Potential candidate genes in these regions that have been implicated in diabetic nephropathy and/or renal damage in models of hypertension include CYBA (or P22PHOX) (16q24), NOX1 (10q22), and NOX3 (6q25.1-q26).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123163.RAsRFokZbfklR6FRiU1Vx79N4Yz_ZdoeiesCD-1Ad6WHQ130_provenance.
• NP123165.RAjXPGoNVdgHzthPqICf6ctCjVYcR37p3OLK7KH8lF-d8130_assertion description "[We report that the PPARG C161T polymorphism is associated with the survival of IgAN patients without hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123165.RAjXPGoNVdgHzthPqICf6ctCjVYcR37p3OLK7KH8lF-d8130_provenance.
• NP123167.RAqAOR0UhD8-Ggsn_BsF_s1zKAZr2eL5PzL5lsRTsFl08130_assertion description "[Deletion of GSTT1 gene might be considered as protective factor for hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123167.RAqAOR0UhD8-Ggsn_BsF_s1zKAZr2eL5PzL5lsRTsFl08130_provenance.
• NP123168.RAhjFht9_jbk7amvMZlfT4fTFjgl3RW2ZHtv05M0IcBvs130_assertion description "[IL-1beta -511C/T and IL-1 RN 86 bp VNTR do not contribute to the aetiology of essential hypertension in the Pakistani Pathan population investigated here ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123168.RAhjFht9_jbk7amvMZlfT4fTFjgl3RW2ZHtv05M0IcBvs130_provenance.
• NP123177.RAnCK592PTTiWJf1OCrDGPAQurOI_Cw2dwub-uEbN0ZSY130_assertion description "[suggested that the GNAS1 T393C polymorphism is associated with ANS activity in youth and may be useful as a genetic marker for hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123177.RAnCK592PTTiWJf1OCrDGPAQurOI_Cw2dwub-uEbN0ZSY130_provenance.
• NP123180.RAnHRmf3rw6dTxGhv3mEz9TMTT2-7YWLVZZuuzdZKMoPM130_assertion description "[Report the effects of the selective ET (A) receptor antagonist, sitaxsentan sodium, in a patient population with pulmonary arterial hypertension that meets traditional inclusion criteria of previous pulmonary arterial hypertension trials ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123180.RAnHRmf3rw6dTxGhv3mEz9TMTT2-7YWLVZZuuzdZKMoPM130_provenance.
• NP123181.RAsr7MRpN68QKGh_H8wKYnZLQBogJ92R-4SC4bS-_Hjbg130_assertion description "[strong and negative correlation of both oxidative stress and ET-1 with renal function stages in hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123181.RAsr7MRpN68QKGh_H8wKYnZLQBogJ92R-4SC4bS-_Hjbg130_provenance.
• NP123183.RAgfLnjVKg9kuEyP7OI5lmdxi6bDf-y9cw3NxMgqq_J9Y130_assertion description "[Interaction between the K121Q polymorphism of the PC-1 gene and birth length affects insulin sensitivity and increases susceptibility to type 2 diabetes and hypertension in adulthood ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123183.RAgfLnjVKg9kuEyP7OI5lmdxi6bDf-y9cw3NxMgqq_J9Y130_provenance.
• NP123184.RAqZVcXGZn1lZgIw9_aFNXEdlnBUkQPCR3k-SjxrwXX5k130_assertion description "[Four of the SNPs and the microsatellite AC008818-1 showed association with stroke after stratification by hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123184.RAqZVcXGZn1lZgIw9_aFNXEdlnBUkQPCR3k-SjxrwXX5k130_provenance.
• NP123185.RAopUuAM3w-PW3BvyLhsMhv9WY6vQxCIKvqC0PRWS4s2k130_assertion description "[Matrix metalloproteinase-9 polymorphism contributes to blood pressure and arterial stiffness in essential hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123185.RAopUuAM3w-PW3BvyLhsMhv9WY6vQxCIKvqC0PRWS4s2k130_provenance.
• NP123186.RAi3NV2H08fyKLBWazZnnbQKOi0DHHl84VKXQ-rn-fl3I130_assertion description "[Circulating pretreatment MMP-9 and TIMP-1 levels were significantly higher in patients with hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123186.RAi3NV2H08fyKLBWazZnnbQKOi0DHHl84VKXQ-rn-fl3I130_provenance.
• NP123187.RAvXXZXRps861WdRYyB9gSUAFQeBgHdnNAsKYTUE1uG2s130_assertion description "[may be involved in the process of arterial stiffening and development of isolated systolic hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123187.RAvXXZXRps861WdRYyB9gSUAFQeBgHdnNAsKYTUE1uG2s130_provenance.
• NP123188.RAiM_mzBSvQMng5joDF66zgHwdLHIuE_smfm14CFKkl1k130_assertion description "[Data show that PON1 55/192 and MMP-3 5A/6A genetic variants are associated with coronary artery disease; PON1 is connected with the number of diseased vessels, and hypertension and hyperlipidemia are related with PON1 192 and MMP-3 in CAD patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123188.RAiM_mzBSvQMng5joDF66zgHwdLHIuE_smfm14CFKkl1k130_provenance.
• NP123192.RArQ_It1tW1XpAHuvXgWrsawYpHPVgQJ6KqVx9lohqC3c130_assertion description "[A/G polymorphisms at codon 637 of the TAP1 gene contributes to the risk of hypertension, possibly via the increases in blood pressure and body mass index ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123192.RArQ_It1tW1XpAHuvXgWrsawYpHPVgQJ6KqVx9lohqC3c130_provenance.
• NP123193.RAjYpqT6BiFtmNSoDqAzeHLNHWYh67v6WagfsWX2w83zw130_assertion description "[Some genotypes constitute a risk factor for hypertension that interacts with stature.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123193.RAjYpqT6BiFtmNSoDqAzeHLNHWYh67v6WagfsWX2w83zw130_provenance.
• NP123198.RAgzamy3Jlhj2pV8riEV0WxB9bYUHhT3ZnlXeD5pbfWvo130_assertion description "[The 4G/4G plasminogen activator inhibitor-1 genotype appears to be associated with an elevated relative risk of developing arterial hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123198.RAgzamy3Jlhj2pV8riEV0WxB9bYUHhT3ZnlXeD5pbfWvo130_provenance.
• NP123201.RAlhN7uSNHkEPkK3ZrHyW65JguSqSgebJ9_QSukLdA-gU130_assertion description "[WNK4 positively regulates TRPV5-mediated Ca transport & inhibitory effect of thiazide-sensitive Na+Cl- cotransporter on this process may be involved in pathogenesis of hypercalciuria of familial hyperkalemic hypertension caused by gene mutation in WNK4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123201.RAlhN7uSNHkEPkK3ZrHyW65JguSqSgebJ9_QSukLdA-gU130_provenance.
• NP123202.RAlJdNzgi2Kthdvxmi-snKFSjBHbeVeVu900sfXeZkLiQ130_assertion description "[Mutations in the WNK4 gene identified in Japanese hypertensives may contribute to hypertension and progression of hypertensive complications to some extent.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123202.RAlJdNzgi2Kthdvxmi-snKFSjBHbeVeVu900sfXeZkLiQ130_provenance.
• NP123206.RAt5908ylnODE7IxWVdF-QEypl-Gd5Hibs95QCAXzNA04130_assertion description "[human renin and human angiotensinogen have roles in development of hypertension in transgenic mice, and may predispose to spontaneous stroke ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123206.RAt5908ylnODE7IxWVdF-QEypl-Gd5Hibs95QCAXzNA04130_provenance.
• NP123207.RAnrUmaLMIfs6qfG-8bCwVKWJ6lozVWf3MRZ_i_dsjtko130_assertion description "[Angiotensinogen/renin transgenic rats develop hypertension/in the heart conduction sytsem leads to ventricular tachycardia and sudden arrhythmic death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123207.RAnrUmaLMIfs6qfG-8bCwVKWJ6lozVWf3MRZ_i_dsjtko130_provenance.
• NP123208.RAv6vMdcumS3xa1INTpWl86CKe6Tyu-6nGksCvZSbMkcA130_assertion description "[Strong association of the renin TaqI polymorphism with essential hypertension in Chinese Han and Tibetan populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123208.RAv6vMdcumS3xa1INTpWl86CKe6Tyu-6nGksCvZSbMkcA130_provenance.
• NP123211.RAtZCT2EXAAgRNMxs8PXyy22XW18Sz4E55cwkhsOA8764130_assertion description "[Genotype GG of the rs5707 polymorphisms of the renin gene were associated with blood pressure levels and risk of hypertension in women over 40 years old ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123211.RAtZCT2EXAAgRNMxs8PXyy22XW18Sz4E55cwkhsOA8764130_provenance.
• NP123222.RAk-p8NL0n4TK4vxD_cGrGlBqo1t8C57AJuVcsEifdkyI130_assertion description "[missense mutations in HSD11B2 do not substantially contribute to essential hypertension in Japanese ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123222.RAk-p8NL0n4TK4vxD_cGrGlBqo1t8C57AJuVcsEifdkyI130_provenance.
• NP123224.RAvUspvkxYzIS9tOKmOAyut55LQByAymREx679Jtrjoa8130_assertion description "[Based on the results of our haplotype-based case-control study, the T-A haplotype may be a genetic marker for essential hypertension, and thus the EC-SOD gene might be a susceptibility gene for it ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123224.RAvUspvkxYzIS9tOKmOAyut55LQByAymREx679Jtrjoa8130_provenance.
• NP123226.RAkqB1A4rVrnc-VbDzLtn0FRmQdXYThH4kBm4Ty25zGn4130_assertion description "[Data show that the alpha-adducin gene TT and ACE II genotypes might be genetic susceptibility factors to hypertension accompanying renal injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123226.RAkqB1A4rVrnc-VbDzLtn0FRmQdXYThH4kBm4Ty25zGn4130_provenance.
• NP123227.RAjVL0hBlVIICQpZ1vvzMI50d3W4wzVyVBIJCyvSsOXdo130_assertion description "[These results indicate relationship between insertion/deletion polymorphism of the ACE gene and plasma plasminogen activator inhibitor levels in the early stage of hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123227.RAjVL0hBlVIICQpZ1vvzMI50d3W4wzVyVBIJCyvSsOXdo130_provenance.
• NP123228.RAq-vK-s8tWy8i0rt-rpb2gwbUe2OKQ6uyW5jBk1vZCp8130_assertion description "[The ACE DD genotype appears to be an independent risk factor for development of hypertension and may explain a significant fraction of incident cases among Hispanics.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123228.RAq-vK-s8tWy8i0rt-rpb2gwbUe2OKQ6uyW5jBk1vZCp8130_provenance.
• NP123232.RAng33PctDIXnolRg26S2-h9NRPOeymc4NjJnSOc9Veig130_assertion description "[ACE1 polymorphism and daily salt intake constitute a gene-environment interaction, which may be further modulated by overweight in hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123232.RAng33PctDIXnolRg26S2-h9NRPOeymc4NjJnSOc9Veig130_provenance.
• NP123233.RAhEecIACCeY45NKuC0V1YjHtLQPywz6FmPkfZg-Kg01U130_assertion description "[The interaction between the ACE gene I/D polymorphism and OSA appears to be an important mechanism in the development of hypertension, particularly in men.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123233.RAhEecIACCeY45NKuC0V1YjHtLQPywz6FmPkfZg-Kg01U130_provenance.
• NP123240.RAmJ0lSyinN4EAHY8F1XO1hzvWqcLkDvj3dm4qGsqXCbs130_assertion description "[Different aortic reflection wave responses following long-term angiotensin-converting enzyme inhibition and beta-blocker in essential hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123240.RAmJ0lSyinN4EAHY8F1XO1hzvWqcLkDvj3dm4qGsqXCbs130_provenance.
• NP123242.RAlGxRG0gJb6duOGpfFb0YmGMyPO5PsrZBvYaAxsEOTjc130_assertion description "[Haptoglobin polymorphism was associated with more severe hypertension and proteinuria in patients with preeclampsia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123242.RAlGxRG0gJb6duOGpfFb0YmGMyPO5PsrZBvYaAxsEOTjc130_provenance.
• NP123243.RAgT8g44KdPR8WH_TVlqp-37a7jCLDvQO5_FQi1zirFIE130_assertion description "[Single-nucleotide polymorphisms of the lymphotoxin alpha gene were not associated with essential hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123243.RAgT8g44KdPR8WH_TVlqp-37a7jCLDvQO5_FQi1zirFIE130_provenance.
• NP123244.RAhIaPlVdLg0gZ4TIEvqAkLg3B4jxhKrYt5xxgGfjbSvk130_assertion description "[The Q89R polymorphism is an independent factor for hypertension in Japanese females.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123244.RAhIaPlVdLg0gZ4TIEvqAkLg3B4jxhKrYt5xxgGfjbSvk130_provenance.
• NP123245.RAr_osFlWJBnHcA6I7jp4Zl3UR3ZKVD8abZULFA5tv00g130_assertion description "[results suggest a protective role of the A724A (c.2171G > A) polymorphism of ATP2A2 in subjects without hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123245.RAr_osFlWJBnHcA6I7jp4Zl3UR3ZKVD8abZULFA5tv00g130_provenance.
• NP123249.RAtizK0VEcNpN-L-crai2RQgGavTYzddprOw1jvrfYRQI130_assertion description "[our results are consistent with the previously reported role of CETP and LPL genetic variants in cardiovascular risk and the possible modulation of the association between hypertension and carotid IMT by APOCIII Sst-1 variant.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123249.RAtizK0VEcNpN-L-crai2RQgGavTYzddprOw1jvrfYRQI130_provenance.
• NP123257.RAnhCsyUj8BK36XGrn8asm-qG3KL5_Gadi6Kb7xXi-kJA130_assertion description "[Association of interleukin-6, interleukin-12, and interleukin-10 gene polymorphisms with essential hypertension in Tatars from Russia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123257.RAnhCsyUj8BK36XGrn8asm-qG3KL5_Gadi6Kb7xXi-kJA130_provenance.
• NP123260.RAtptBd71DZ7D6oZ5kzWmBszqz87nKy1GfNT1Rf1Xpp5k130_assertion description "[A possible synergistic effect to salt-sensitive hypertension was found by combining EDNRB with angiotensinogen genotypes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123260.RAtptBd71DZ7D6oZ5kzWmBszqz87nKy1GfNT1Rf1Xpp5k130_provenance.
• NP123267.RAhwXR-Nexpo1miWoXlniYtFhbHbo1KFMGmzW3EMofUyc130_assertion description "[IGF1 levels in the low normal range are associated with hypertension and diabetes in subjects without pituitary and cardiovascular diseases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123267.RAhwXR-Nexpo1miWoXlniYtFhbHbo1KFMGmzW3EMofUyc130_provenance.
• NP123268.RAjhQISkPxpxJDl9dTpfeGKTLLoo-VybMGL3JiLgNjJqM130_assertion description "[The Gly40Ser polymorphism of the GCGR gene is associated with higher risk of hypertension and with enhanced proximal tubular sodium reabsorption.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123268.RAjhQISkPxpxJDl9dTpfeGKTLLoo-VybMGL3JiLgNjJqM130_provenance.
• NP123271.RAlFCuULFz1cTQLDx-zxRQj41AhdLMZ2YR_jU7p1gT468130_assertion description "[Novel signaling network relevant to pulmonary artery hypertension underscored by BMPR2 mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123271.RAlFCuULFz1cTQLDx-zxRQj41AhdLMZ2YR_jU7p1gT468130_provenance.
• NP123275.RAtpNtF3oehSYD18c6nm-j55dBu0vVyGhDTx2Zl7Kzbfs130_assertion description "[Somatic loss of wild-type BMPR2 alleles is unlikely to play a significant role in the pathogenesis of familial pulmonary arterial hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123275.RAtpNtF3oehSYD18c6nm-j55dBu0vVyGhDTx2Zl7Kzbfs130_provenance.
• NP123287.RAjEI_tm_H5Qlpp5oqY6OQityNphmZ6pJJa9HvzETsjeg130_assertion description "[classical risk factors such as smoking, hypertension, low alcohol intake and elevated triglyceride concentration were relatively more important for development of CPAD than MBL deficiency in SLE ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123287.RAjEI_tm_H5Qlpp5oqY6OQityNphmZ6pJJa9HvzETsjeg130_provenance.
• NP123298.RAtm4ca5mlzbTHs_4byMBlP9WQMQeadux8uN8ebWAFRAY130_assertion description "[The human Nedd4L gene, especially the evolutionarily new isoform I, is a candidate gene for hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123298.RAtm4ca5mlzbTHs_4byMBlP9WQMQeadux8uN8ebWAFRAY130_provenance.
• NP123299.RAvwKY7fSdQx-DZ-GdIcwaHC3q2PX8f9zw_-_lDzaD7YA130_assertion description "[study reports the association of human ATP1A1 (P < 0.000005) and Dear (P < 0.03) with hypertension in a relatively isolated, case/control hypertension cohort from northern Sardinia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123299.RAvwKY7fSdQx-DZ-GdIcwaHC3q2PX8f9zw_-_lDzaD7YA130_provenance.
• NP123300.RAmumhhvR9SnFc7AjS-FP7zpfnU6X_DqFi7UNRc_kxBX4130_assertion description "[Mice with the ouabain-sensitive " human-like " alpha1 isoform developed ACTH-induced hypertension to greater extent than WT animals ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123300.RAmumhhvR9SnFc7AjS-FP7zpfnU6X_DqFi7UNRc_kxBX4130_provenance.
• NP123307.RAmwPciSUK99G1HHFart615zHkgGEUHvTcf7YsQBeU0Ok130_assertion description "[The -344C allele of the CYP11B2 may play a role in genetic predisposition to developing essential hypertension in Hani and Yi minorities of China.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123307.RAmwPciSUK99G1HHFart615zHkgGEUHvTcf7YsQBeU0Ok130_provenance.
• NP123319.RAr57Wc02qAvUU0R4QPiIbRmxrfEtqaUk1WrLxqsNRnKA130_assertion description "[We successfully identified haplotypes of the PGIS gene, and these haplotypes were not associated with essential hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123319.RAr57Wc02qAvUU0R4QPiIbRmxrfEtqaUk1WrLxqsNRnKA130_provenance.
• NP123320.RAiBrdRKcQKNYlM31qZa1UaZgDVhK3KCfe3KKOwySQxRA130_assertion description "[splicing mutation found in hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123320.RAiBrdRKcQKNYlM31qZa1UaZgDVhK3KCfe3KKOwySQxRA130_provenance.
• NP123332.RAi8wKqKqS3bGghFs9lKUHHDi0qta7wLkxGCI7VtA8FtM130_assertion description "[the activity of MMP-2 in the internal mammary artery is correlated with age, hypertension, diabetes and estimated glomerular filtration rate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123332.RAi8wKqKqS3bGghFs9lKUHHDi0qta7wLkxGCI7VtA8FtM130_provenance.
• NP123334.RAofikx1kPPXxlxuskMz1UNI_JG0b24DMQzPgjsSuaZz0130_assertion description "[genotyped 5 single nucleotide polymorphisms in the ECE1 gene in 1, 873 individuals from a general Japanese population and identified one associated with hypertension in women ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123334.RAofikx1kPPXxlxuskMz1UNI_JG0b24DMQzPgjsSuaZz0130_provenance.
• NP123336.RArVvPol6PQ-iuBdCU9E8yAD1ky76i0kg4zeiBnH5jrUs130_assertion description "[The heart possesses imidazoline I1-receptors that are up-regulated in the presence of hypertension or heart failure, which suggests their involvement in cardiovascular regulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123336.RArVvPol6PQ-iuBdCU9E8yAD1ky76i0kg4zeiBnH5jrUs130_provenance.
• NP123343.RAgBfXqNsjhO7-ghOMCxAyvi5Wxa8hM10LyoRHgBHiqLk130_assertion description "[Significant association between several SNPs and hypertension in US whites, Greek whites, and African-Americans/variation in NEDD4L may play role in development or progression of some forms of hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123343.RAgBfXqNsjhO7-ghOMCxAyvi5Wxa8hM10LyoRHgBHiqLk130_provenance.
• NP123347.RAna9Tp9F5h8huBT-82v8-EwATfh3bhCNo5OXZoZO614M130_assertion description "[rs700518 and rs10046, as well as a haplotype constructed with rs1870049 and rs10046, can be used as genetic markers for gender-specific essential hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123347.RAna9Tp9F5h8huBT-82v8-EwATfh3bhCNo5OXZoZO614M130_provenance.
• NP123350.RAgNgxAug1J8dg1piPLAZ14W3rwwRfj_-B3sDhzCgDskc130_assertion description "[An intramuscular injection of AAV-PGIS prevents monocrotaline-pulmonary arterial hypertension in rats and provides a new therapeutic alternative for preventing pulmonary arterial hypertension in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123350.RAgNgxAug1J8dg1piPLAZ14W3rwwRfj_-B3sDhzCgDskc130_provenance.
• NP123356.RAl4Mua8YaPNifOmXjYKfLyutwwPP0lRiA01Myyouf5uY130_assertion description "[the p22 (phox) gene has a role in hypertension [review]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123356.RAl4Mua8YaPNifOmXjYKfLyutwwPP0lRiA01Myyouf5uY130_provenance.
• NP123357.RAniEUTJX0C7v561qUNzA6IwnMxTP3KTNN2pHAbFgkddI130_assertion description "[Potential candidate genes in these regions that have been implicated in diabetic nephropathy and/or renal damage in models of hypertension include CYBA (or P22PHOX) (16q24), NOX1 (10q22), and NOX3 (6q25.1-q26).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123357.RAniEUTJX0C7v561qUNzA6IwnMxTP3KTNN2pHAbFgkddI130_provenance.
• NP123364.RAvwpHTWIdP-Qkb4yFWeq2CQ41RU5Uv14T29dV9ux13Fw130_assertion description "[Polymorphism of uncoupling protein 2 gene is associated with hypertension, and suggests the possibility of uncoupling protein 2 gene as a target molecule for studies on the etiology and treatment of hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123364.RAvwpHTWIdP-Qkb4yFWeq2CQ41RU5Uv14T29dV9ux13Fw130_provenance.
• NP123368.RAuNmNEQlrhoDGHc8z0Vav9srEPD2pY5KqeWJnHSITO5c130_assertion description "[This review discusses the importance of magnesium in vascular biology and implications in hypertension and highlights the transport systems, particularly TRPM6--REVIEW ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123368.RAuNmNEQlrhoDGHc8z0Vav9srEPD2pY5KqeWJnHSITO5c130_provenance.
• NP123373.RAjVEEpwUswQVFrDjLvx5vuNJxMj9MEaVsTKku2xHl3DM130_assertion description "[cystatin C level is a useful and convenient parameter of renal function, and may also prove to be an early marker of the severity of end-organ damage in patients with essential hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123373.RAjVEEpwUswQVFrDjLvx5vuNJxMj9MEaVsTKku2xHl3DM130_provenance.
• NP123374.RArsIZF3RSzvNxRkpcrsP8RrbVLGHz68Ujg9D0os7Jm98130_assertion description "[results suggest that the TGF-beta1 gene at chromosome 19q13.1 may be a candidate susceptibility locus for hypertension in Japanese women ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123374.RArsIZF3RSzvNxRkpcrsP8RrbVLGHz68Ujg9D0os7Jm98130_provenance.
• NP123375.RArWWECZx1K8Bw9B0z4HG9HtOqBc0RP89reJdsYsdrgLM130_assertion description "[Data suggest that TGFB1 gene polymorphism is associated to clinical characteristics suitable to recognize hypertensives with a higher severity of hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123375.RArWWECZx1K8Bw9B0z4HG9HtOqBc0RP89reJdsYsdrgLM130_provenance.
• NP123379.RAuyHxhy-rR9NJ3JubBOE4bdg8z7oW_jaloQIo3QOo1LU130_assertion description "[Ang II decreases activity of 11beta-HSD2 by AT2 receptor- and MAPK-dependent mechanism/activity of 11beta-HSD2 increases intracellular availability of cortisol/be relevant for pathogenesis of hypertension and preeclampsia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123379.RAuyHxhy-rR9NJ3JubBOE4bdg8z7oW_jaloQIo3QOo1LU130_provenance.
• NP123382.RAjPESBnd64rairgmBF-a2BhWwXxjxCIQX_pvPq33nUGU130_assertion description "[Both DraI restriction fragment length polymorphism in ADRA2A and ADRA2C (Del 322 to 325) can be excluded as major candidate alleles for hypertension in blacks/Alpha2 adrenergic receptors ADRA2A and ADRA2C) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123382.RAjPESBnd64rairgmBF-a2BhWwXxjxCIQX_pvPq33nUGU130_provenance.
• NP123383.RAqAVRJfjCmp8e6Nm6mD7OaIKASZqYNtOpE9QqpjMe_Qg130_assertion description "[A variant of the ADRA2B gene is associated with essential hypertension with or without type 2 diabetes in Malaysian subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123383.RAqAVRJfjCmp8e6Nm6mD7OaIKASZqYNtOpE9QqpjMe_Qg130_provenance.
• NP123389.RAqwX0Doe3GnzlVhXnWpnwp1xLamfmySdZyjqkWjOuLOk130_assertion description "[AP-1 activation is involved in the transcriptional up-regulation of sEH by angiotensin II (Ang II) in endothelial cells, which may contribute to Ang II-induced hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123389.RAqwX0Doe3GnzlVhXnWpnwp1xLamfmySdZyjqkWjOuLOk130_provenance.
• NP123391.RAv3aSuomgryU8De3QQCerNzHSWdP4oxifMHvg8D94o04130_assertion description "[In patients with reperfused acute myocardial infarction and LV dysfunction, hypertension was not associated with a different pattern of serum procollagen release (serum BNP, PICP, ICTP, and PIIINP) and ventricular remodelling at 6 months of follow-up.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123391.RAv3aSuomgryU8De3QQCerNzHSWdP4oxifMHvg8D94o04130_provenance.
• NP123392.RAtyV7nblfX5D0dF5kwFXASeb6bS2Nhf__Nu_SbnbqVGc130_assertion description "[plasma total homocysteine is a determinant of TNF-alpha in hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123392.RAtyV7nblfX5D0dF5kwFXASeb6bS2Nhf__Nu_SbnbqVGc130_provenance.
• NP123394.RAn1erfl3NaEuSEdzu9o_HF2ptbfAy6KpBEhq6p7cmrGE130_assertion description "[patients with hypertension and congestive heart failure demonstrated the DD angiotensin-converting enzyme genotype and the CC angiotensin II type 1 receptor genotype ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123394.RAn1erfl3NaEuSEdzu9o_HF2ptbfAy6KpBEhq6p7cmrGE130_provenance.
• NP123395.RApWJzMBrQ2NGM41ISb0F1NQb3e5iqw6pIs7KsbdHN_rU130_assertion description "[statistical evidence for the association of AGT promoter region with essential hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123395.RApWJzMBrQ2NGM41ISb0F1NQb3e5iqw6pIs7KsbdHN_rU130_provenance.
• NP123399.RApfOVsSVLSmZk3PxcnI1Ff51Jdz-8Ock9hC2Stk3RFao130_assertion description "[human renin and human angiotensinogen have roles in development of hypertension in transgenic mice, and may predispose to spontaneous stroke ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123399.RApfOVsSVLSmZk3PxcnI1Ff51Jdz-8Ock9hC2Stk3RFao130_provenance.
• NP123401.RAnJb_MM1rSFHFtzakml48Ds4UBXTANkfqqFSx30JWX88130_assertion description "[Association has been confirmed between the Lys528Arg polymorphism of the adipocyte-derived leucine aminopeptidase gene and essential hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123401.RAnJb_MM1rSFHFtzakml48Ds4UBXTANkfqqFSx30JWX88130_provenance.
• NP123407.RAlbrv_fasZvE4RsYVE7bMIgFf8Q1jeOIX58s2V89tW8Y130_assertion description "[ACE2 might play an important role in maintaining a balanced status of local renin-angiotensin system synergistically with ACE by counterregulatory effects confounded by the presence of hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123407.RAlbrv_fasZvE4RsYVE7bMIgFf8Q1jeOIX58s2V89tW8Y130_provenance.
• NP123412.RAgVEL-0yuqsYD5hcvIFp5szljskJYsxCzTHUVSxOmuZ8130_assertion description "[Arg389Gly polymorphism of the ADRB1 gene confers higher risk of left ventricular hypertrophy in human essential hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123412.RAgVEL-0yuqsYD5hcvIFp5szljskJYsxCzTHUVSxOmuZ8130_provenance.
• NP123416.RAkWloYu_NZIifia-oHOP2NNH-e3bcUlBXQSWaYPR_XGM130_assertion description "[These data provide evidence for a potential clinical relevance for alpha (1) -AAB in hypertensive patients, and the notion of immunity as a possible cause of hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123416.RAkWloYu_NZIifia-oHOP2NNH-e3bcUlBXQSWaYPR_XGM130_provenance.
• NP123418.RAvaqG5eB7DBAeYTuCblnCXKXMUojRbJ0AchMyFUCMrRI130_assertion description "[CNP G2628A polymorphism made an even greater contribution to hypertension in the younger subpopulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123418.RAvaqG5eB7DBAeYTuCblnCXKXMUojRbJ0AchMyFUCMrRI130_provenance.
• NP123424.RAuP4Jo5AyZ6uzepFQFmbhKY_7PtfD0AbiCWj_syYyMBE130_assertion description "[A branch-site mutation leading to abnormal splicing of exon 13 of the endoglin transcript was identified in a child with hereditary hemorrhagic telangiectasia related pulmonary arterial hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123424.RAuP4Jo5AyZ6uzepFQFmbhKY_7PtfD0AbiCWj_syYyMBE130_provenance.
• NP123438.RAvC1SK1BOXxcKFfp27wYUlR_XpnJStZhfWyOR6b_srAI130_assertion description "[Single nucleotide polymorphisms (SNPs) in the F11 receptor gene (F11R) are associated with hypertension and obesity in Hong Kong Chinese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123438.RAvC1SK1BOXxcKFfp27wYUlR_XpnJStZhfWyOR6b_srAI130_provenance.
• NP123440.RAh_bisWKsCdZQ4zNhATUENztK8EA7BdvKMQWydrtci-A130_assertion description "[results suggest that ND2-237 Leu/Met polymorphism is associated with hypertension and that modification of hypertension risk is dependent on alcohol consumption in middle-aged Japanese men ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123440.RAh_bisWKsCdZQ4zNhATUENztK8EA7BdvKMQWydrtci-A130_provenance.
• NP123444.RAtqehWo8W4skAs_2Tmrw-x3872KtMncmkpwm09Q_aXfg130_assertion description "[GLUT12 protein was localized to the apical membrane of human and rat distal tubules and collecting ducts/of both GLUT1 and GLUT12 are elevated in animal models of hypertension and diabetic nephropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123444.RAtqehWo8W4skAs_2Tmrw-x3872KtMncmkpwm09Q_aXfg130_provenance.
• NP123450.RAjqm1VrJhnqaIOhWl81cOHt5aKF3nizJFQyv2NCHg8Ik130_assertion description "[nitric oxide synthase 3 is also related to hypertension, endothelial dysfunction and variation on serum cholesterol in young adults with acute myocardial infarction ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123450.RAjqm1VrJhnqaIOhWl81cOHt5aKF3nizJFQyv2NCHg8Ik130_provenance.
• NP123451.RAgRBinBV35jzNearjPyhJKrXvKOXRyGXdxr-aWd-V0Ec130_assertion description "[The ALK-1 mutant R484Q within the highly conserved NANDOR box region was found in an infant with idiopathic pulmonary arterial hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123451.RAgRBinBV35jzNearjPyhJKrXvKOXRyGXdxr-aWd-V0Ec130_provenance.
• NP123453.RAi6J4om3EznTxh-asRVVMgWweEC_R73W5GygD9IZy9YA130_assertion description "[distribution of -63A/C polymorphism of human glutathione S-transferase M3 (GSTM3) gene in Chinese Han population and the association of -63A/C polymorphism with essential hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123453.RAi6J4om3EznTxh-asRVVMgWweEC_R73W5GygD9IZy9YA130_provenance.
• NP123456.RAk_Wjehonu2XDKXqnDmCb3iIa8WsVIT6u0bFgkU2Gf1M130_assertion description "[A nonsynonymous polymorphism in ALOX12 is associated to essential hypertension and to urinary levels of 12 (S) -HETE, thus suggesting a role for this gene in this disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123456.RAk_Wjehonu2XDKXqnDmCb3iIa8WsVIT6u0bFgkU2Gf1M130_provenance.
• NP123459.RAh1SfLCDf4GhxS8gkNWSb93sIiji3EB1JqkTah6jlJOI130_assertion description "[Catechol-O-methyltransferase (COMT (deficiency in mice increases the availability of L-DOPA, leading to enhanced dopaminergic tone, which may be associated with resistance to salt-induced hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123459.RAh1SfLCDf4GhxS8gkNWSb93sIiji3EB1JqkTah6jlJOI130_provenance.
• NP123461.RAgXcZQuNz3AFi5Gc0eSWz6c7gg2bFaRFJUqMtqdrwgiM130_assertion description "[Platelet activation and platelet CD62 may participate in the accelerated target organ injury observed in high risk patients with severe hypertension ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123461.RAgXcZQuNz3AFi5Gc0eSWz6c7gg2bFaRFJUqMtqdrwgiM130_provenance.
• NP123462.RAv65iAifsJLX1LDZT9Y4v7kq0HqmyyWAIeZ8ifOAODEs130_assertion description "[2 novel mutations (K5E, G12S) were identified in 7 patients withcardio-facio-cutaneous syndrome, Costello syndrome or Noonan syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123462.RAv65iAifsJLX1LDZT9Y4v7kq0HqmyyWAIeZ8ifOAODEs130_provenance.
• NP123464.RAgYwP9kSfhpbsOwvcHO_xvIIeYHYbXFIg4r9WPZKatj4130_assertion description "[Mutations in the KRAS are associated with Noonan syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123464.RAgYwP9kSfhpbsOwvcHO_xvIIeYHYbXFIg4r9WPZKatj4130_provenance.
• NP123468.RArn9RrdfETykUuZQVRc77i-BndLWGuFub86oDmY_-Cxk130_assertion description "[Study identified 5 mutations in RAF1 in 10 individuals with Noonan syndrome; those with mutations causing changes in the CR2 domain of RAF1 had hypertrophic cardiomyopathy, while those with mutations leading to changes in the CR3 domain did not.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123468.RArn9RrdfETykUuZQVRc77i-BndLWGuFub86oDmY_-Cxk130_provenance.
• NP123472.RAh2b-yPQRDCnGNKXemREmizJinEQIugMChBV9uaiqoCw130_assertion description "[Patients with SOS1 mutations range from Noonan syndrome to cardio-facio-cutaneous syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123472.RAh2b-yPQRDCnGNKXemREmizJinEQIugMChBV9uaiqoCw130_provenance.
• NP123474.RArH6lpRaQfqf0MPMYNh9hN_Jpe5Y5eSjetWZRXQ4JOK0130_assertion description "[In more than half the patients with Noonan Syndrome a mutation in the PTPN11 gene was identified.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123474.RArH6lpRaQfqf0MPMYNh9hN_Jpe5Y5eSjetWZRXQ4JOK0130_provenance.
• NP123477.RAmApTPs1VnPHIByqL6_OKewde1G5L84Y5RSx08IdDdsw130_assertion description "[understanding of Noonan syndrome and the LEOPARD syndrome pathogenesis will require solving the paradox that mutations oppositely influencing the biochemical activity of SHP-2 result in similar syndromes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123477.RAmApTPs1VnPHIByqL6_OKewde1G5L84Y5RSx08IdDdsw130_provenance.
• NP123479.RAmqlLG6ZETFWVR9c32mDaA-Cm35mNlR48DRd18qBg_hI130_assertion description "[1226 G-- > C causes amino acid substitution G409A and results in Noonan Syndrome/in this particular region of SHP-2 may have effects on the protein that differ from those of the classical mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123479.RAmqlLG6ZETFWVR9c32mDaA-Cm35mNlR48DRd18qBg_hI130_provenance.
• NP123488.RAuVgZtRLicWwwHIBcbNGtlLBNQChrEaskJeeE59XoCUs130_assertion description "[Recombinant human growth hormone has significant protective effects on intestinal mucosa barrier in obstructive jaundice and reduces intestinal translocation of bacteria and endotoxin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123488.RAuVgZtRLicWwwHIBcbNGtlLBNQChrEaskJeeE59XoCUs130_provenance.

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