Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP123880.RAphGvFT7-D1tHQpz7GeTx8fcynIAKMw8xXWeDpwSh5Xw130_assertion description "[SORBS1 polymorphism does not play a major role in premature pubarche, hyperandrogenism, and/or polycystic ovary syndrome in children and adolescent girls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123880.RAphGvFT7-D1tHQpz7GeTx8fcynIAKMw8xXWeDpwSh5Xw130_provenance.
- NP123883.RAkm6Urp_DB8DrJCIsdCN5200U61QFYhUI0dpUAvhk0UY130_assertion description "[data demonstrate cell-specific alterations in IRS protein concentrations in theca cells from polycystic ovaries consistent with exaggerated amplification of the insulin signal & which may play a role in ovarian hyperandrogenism & thecal hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123883.RAkm6Urp_DB8DrJCIsdCN5200U61QFYhUI0dpUAvhk0UY130_provenance.
- NP123885.RArcfqoR5FWxJC-dHw4qKbIDV2gtqhfyq7h8lj_EN-7SU130_assertion description "[Visfatin has a role in insulin resistance and markers of hyperandrogenism in lean PCOS patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123885.RArcfqoR5FWxJC-dHw4qKbIDV2gtqhfyq7h8lj_EN-7SU130_provenance.
- NP123887.RAuOxoFMMdnphzBaVdQ32Pb_VMyEvdHwFcoJN-WXK8SAw130_assertion description "[Novel mutations in CYP21 detected in individuals with hyperandrogenism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123887.RAuOxoFMMdnphzBaVdQ32Pb_VMyEvdHwFcoJN-WXK8SAw130_provenance.
- NP123888.RAqArwcccBXYQfgM0CnsO7isOKXW0_IQH59jOcXKvq66U130_assertion description "[methionine 196 arginine polymorphism in exon 6 of the TNF receptor 2 gene (TNFRSF1B) is associated with the polycystic ovary syndrome and hyperandrogenism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123888.RAqArwcccBXYQfgM0CnsO7isOKXW0_IQH59jOcXKvq66U130_provenance.
- NP123896.RAh-r0R_pxXhHqQKVv4GkEDTi0EZu03TP1XtsMOyKIhLY130_assertion description "[carriage of the GAA haplotype in FGB is associated with decreased mortality and less organ dysfunction in a cohort of critically ill patients with sepsis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123896.RAh-r0R_pxXhHqQKVv4GkEDTi0EZu03TP1XtsMOyKIhLY130_provenance.
- NP123899.RAmQnHZNqyMKpoYiaDRDWictzloYDik1WaHNtorYGE4K4130_assertion description "[MMP and TIMP may be involved in the feto-neonatal development and may contribute to the pathogenesis of bronchopulmonary dysplasia and/or intraventricular hemorrhage in critically ill preterm neonates ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123899.RAmQnHZNqyMKpoYiaDRDWictzloYDik1WaHNtorYGE4K4130_provenance.
- NP123900.RAleDQ4qFtTM62188vu_Yj8FR7Nl0sNH02FU0QjLw3OLk130_assertion description "[MMP and TIMP may be involved in the feto-neonatal development and may contribute to the pathogenesis of bronchopulmonary dysplasia and/or intraventricular hemorrhage in critically ill preterm neonates ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123900.RAleDQ4qFtTM62188vu_Yj8FR7Nl0sNH02FU0QjLw3OLk130_provenance.
- NP123901.RAptxLLtIDQhmSGsGthMEgLqZ5dSSt-ieSvN5xqYau2AA130_assertion description "[Critically ill children are characterized by low levels of IGF-I and -II as well as IGFBP-3 accompanied by elevated levels of GH, probably reflecting the development of peripheral GH resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123901.RAptxLLtIDQhmSGsGthMEgLqZ5dSSt-ieSvN5xqYau2AA130_provenance.
- NP123909.RAh_CHNhq0ufk_jKHcGDBR4t-QEKGgoG_lUGv0ZHpPo8A130_assertion description "[CD14 polymorphism associated with increased prevalence of gram-negative bacterial infection in critically ill adults ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123909.RAh_CHNhq0ufk_jKHcGDBR4t-QEKGgoG_lUGv0ZHpPo8A130_provenance.
- NP123914.RApFwEP2GdeN7cDYlS5BI-lR-LSg8NBrRd0XfVaT6_-co130_assertion description "[Study demonstrated that phosphorylated-Akt-negative and PTEN-positive expression was a predictor of survival for patients with advanced endometrial carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123914.RApFwEP2GdeN7cDYlS5BI-lR-LSg8NBrRd0XfVaT6_-co130_provenance.
- NP123915.RAtl9rzVI1MOcPWgFDuseUs5eRgLvQPyyYUs7a3HIaVzE130_assertion description "[High levels of p-AKT expression occurred independently of the presence of PTEN or PIK3CA mutations in endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123915.RAtl9rzVI1MOcPWgFDuseUs5eRgLvQPyyYUs7a3HIaVzE130_provenance.
- NP123918.RAmFWlVHSw3hcdLXg-vqb_m7ksc1cztILf4BCB911pwjA130_assertion description "[High levels of p-AKT expression occurred independently of the presence of PTEN or PIK3CA mutations in endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123918.RAmFWlVHSw3hcdLXg-vqb_m7ksc1cztILf4BCB911pwjA130_provenance.
- NP123919.RArCssVHRiiYJ0Qf5FNXOLCfMaHDWJCRw3AoFt0QoPmcU130_assertion description "[results confirm that PIK3CA mutations are frequent in endometrial carcinoma and support the hypothesis that PIK3CA mutations may have an additive effect to PTEN monoallelic inactivation in endometrial carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123919.RArCssVHRiiYJ0Qf5FNXOLCfMaHDWJCRw3AoFt0QoPmcU130_provenance.
- NP123920.RAlNJP4Pnl98Ip_DI5uUQABSyhTIgeDPW4A1ynYXqamyY130_assertion description "[PIK3CA mutations are associated with myometrial invasion and tumors with PIK3CA mutations in exon 20 are frequently high-grade, invasive endometrial carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123920.RAlNJP4Pnl98Ip_DI5uUQABSyhTIgeDPW4A1ynYXqamyY130_provenance.
- NP123924.RAogpH_RGAhsNWkyKb25NarDLR2oTZyZdWTz0TBDKFyTs130_assertion description "[Loss of PR expression in human endometrial cancer may lead to development of a more invasive phenotype of the respective tumor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123924.RAogpH_RGAhsNWkyKb25NarDLR2oTZyZdWTz0TBDKFyTs130_provenance.
- NP123937.RAh0aJj0-fGsdBZVUBOnpZJaGD9g0l0JD6o4kamxVyBXY130_assertion description "[high frequency RASSF1A methylation observed in endometrioid endometrial carcinoma; no association was observed with the development of recurrent disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123937.RAh0aJj0-fGsdBZVUBOnpZJaGD9g0l0JD6o4kamxVyBXY130_provenance.
- NP123940.RAuGx3X1LZOjWPaS0wowZYyLsJ6jPS_NjrpIk2iCmAPvo130_assertion description "[Our data suggest that erbB-1/erbB-2 overexpression is a direct effect of higher than normal transcriptional activity of the encoding genes in a subset of human endometrial carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123940.RAuGx3X1LZOjWPaS0wowZYyLsJ6jPS_NjrpIk2iCmAPvo130_provenance.
- NP123944.RAjnf6uh4eW-ZnR6n9YffMddfICLxALBti1qMkiY6czMw130_assertion description "[Hypomethylation is an important mechanism of regulating the expression of the S100A4 gene in endometrial carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123944.RAjnf6uh4eW-ZnR6n9YffMddfICLxALBti1qMkiY6czMw130_provenance.
- NP123945.RArbt0oU4UoMifmZDoQRp_JxIg37LYwAOjn8I-VhZfEUI130_assertion description "[Hif-1 alpha, which is related to tissue hypoxia in endometrial cancer, is associated with overexpression of Ob and ObR (leptin and leptin receptor).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123945.RArbt0oU4UoMifmZDoQRp_JxIg37LYwAOjn8I-VhZfEUI130_provenance.
- NP123947.RAoCmmLrV0hDlqZuRNRavfCUrDtrAoEN5jmN6zaIqRS30130_assertion description "[Increased erythropoietin receptor expression is associated with advanced-stage disease, lymphovascular invasion, lymph node metastasis of endometrial carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123947.RAoCmmLrV0hDlqZuRNRavfCUrDtrAoEN5jmN6zaIqRS30130_provenance.
- NP123951.RAqaVHJBr15ISEFCHV3rVzgprp0VXFam4WLPTxgpww1g4130_assertion description "[Positive correlation is observed between leptin (Ob) receptor and hypoxia-inducible factor 1 alpha subunit (HIF-1alpha) expression in endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123951.RAqaVHJBr15ISEFCHV3rVzgprp0VXFam4WLPTxgpww1g4130_provenance.
- NP123956.RApWoO93kjJc-zsh623pS07kJ-jWwoVIXE6-Oj-dBf4_U130_assertion description "[Overexpression of ESRA suppresses gap junctional intercellular communication in endometrial carcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123956.RApWoO93kjJc-zsh623pS07kJ-jWwoVIXE6-Oj-dBf4_U130_provenance.
- NP123957.RAtcVyDBZ80zEC1iseGv-AsOHm5O0ZBrUekatghAJ6xgs130_assertion description "[The constitutively activated MAP kinase cascade in endometrial cancer cells enhances ERalpha transcriptional activity via the AF1 domain/activation pathway may be involved in the stimulatory effect of tamoxifen on endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123957.RAtcVyDBZ80zEC1iseGv-AsOHm5O0ZBrUekatghAJ6xgs130_provenance.
- NP123960.RAgamepo81e6iMWtgNZsT1BvfXZKz6c57xqkC2aQvYg6o130_assertion description "[The combination of the MDM2 SNP309 and the three TP53 polymorphisms appear to be related to a higher grade of endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123960.RAgamepo81e6iMWtgNZsT1BvfXZKz6c57xqkC2aQvYg6o130_provenance.
- NP123964.RAoIqOd0WdAIoXmEOJCELvH6jjrEXYgiTbOIrnypXMG7U130_assertion description "[Positive staining of p53 was significantly correlated with increased stage, lymph node metastases, and a nonendometrioid histology in endometrial carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123964.RAoIqOd0WdAIoXmEOJCELvH6jjrEXYgiTbOIrnypXMG7U130_provenance.
- NP123968.RAkMJgzSGyAat8kgtY2XqQvxVvmMDoKOW02BMDGUHiYeg130_assertion description "[Cdc25B may play important roles in the development and progression of endometrioid endometrial carcinoma and clear cell carcinoma and uterine pappillary serous carcinoma by different mechanism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123968.RAkMJgzSGyAat8kgtY2XqQvxVvmMDoKOW02BMDGUHiYeg130_provenance.
- NP123970.RArlTk2JXERNjSMoIwVJ1V5Y9yPJbX3c4XDz6SB4VYDn0130_assertion description "[TCF4 expression mediated by beta-catenin/p300 may be important for initial steps during trans-differentiation of endometrial carcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123970.RArlTk2JXERNjSMoIwVJ1V5Y9yPJbX3c4XDz6SB4VYDn0130_provenance.
- NP123972.RAow-UR_G-IMsTxj6YJxdPRpmBD4C5-nI6foxPR7SIuUM130_assertion description "[Epithelial versican expression was significantly higher in patients with lymph node metastasis of endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123972.RAow-UR_G-IMsTxj6YJxdPRpmBD4C5-nI6foxPR7SIuUM130_provenance.
- NP123977.RAn47M5HPUmPlGzczu6tanS8k_7n7JQ8LW1Iat2n0y81o130_assertion description "[AIB1-Delta3 causes a significant increase in the efficacy of 17beta-estradiol at both estrogen receptor-alpha (ER-alpha) and ER-beta in ovarian, breast and endometrial cancer cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123977.RAn47M5HPUmPlGzczu6tanS8k_7n7JQ8LW1Iat2n0y81o130_provenance.
- NP123980.RAnq6w2T2W1uyzUKI7yVA9cgX0RRAr22gOegPGEltcNWQ130_assertion description "[upregulation of syndecan-1 may be a critical element for endometrial cancers in maintaining their viability ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123980.RAnq6w2T2W1uyzUKI7yVA9cgX0RRAr22gOegPGEltcNWQ130_provenance.
- NP123984.RAjQ4tR5XlGTCUC6614xYXVFiOGQMBH0-pD7lR_gFkZbs130_assertion description "[The lack of association between MSH2 protein expression and Microsatellite instability in endometrial cancer samples was observed ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123984.RAjQ4tR5XlGTCUC6614xYXVFiOGQMBH0-pD7lR_gFkZbs130_provenance.
- NP123991.RAplM3ttWa2V2adCMxNe8tvG2wY6FOkh_OAYvFt_JOXfs130_assertion description "[alteration of p16 could play an etiologic role, without any association to HPV infections, in rare endometrial carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123991.RAplM3ttWa2V2adCMxNe8tvG2wY6FOkh_OAYvFt_JOXfs130_provenance.
- NP123995.RAlDGybAMcVKSZSfMFAe7Tqs3N7D6pKCNzvtvkYC5CfFs130_assertion description "[COX-2, MMP-2 and MMP-9 were expressed in a high percentage of primary endometrial carcinomas and their expressions may be associated closely with parameters of tumor aggressiveness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP123995.RAlDGybAMcVKSZSfMFAe7Tqs3N7D6pKCNzvtvkYC5CfFs130_provenance.
- NP124001.RAjFhFo5LBj0t-lUnTSHRtVAKFI1WlwrjXqFeWun8Aq2s130_assertion description "[COX-2 is upregulated in endometrial cancer and facilitates tumor growth via angiogenesis produced in associated with VEGF and TP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124001.RAjFhFo5LBj0t-lUnTSHRtVAKFI1WlwrjXqFeWun8Aq2s130_provenance.
- NP124003.RAo-NW2Kbo1seKT4Qa1ulwFTm8ZFzUaCJ4oIh0n-wqKhc130_assertion description "[hMLH1 is one of the most commonly mutated MMR genes in endometrial carcinomas and colorectal carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124003.RAo-NW2Kbo1seKT4Qa1ulwFTm8ZFzUaCJ4oIh0n-wqKhc130_provenance.
- NP124009.RAg1uC9t7ORPd05V36zjTkddzb8JomT534YCBfefAoDiw130_assertion description "[KU-CT-1 is a new cancer testis antigen that is expressed in pancreatic, lung, and endometrial cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124009.RAg1uC9t7ORPd05V36zjTkddzb8JomT534YCBfefAoDiw130_provenance.
- NP124013.RAq5N_YZGEXU3dezvH3me854YkWYTRhMCzGwO3pYskKE8130_assertion description "[Decreased estrogen sulfotransferase expression is associated with estrogen-dependent endometrial carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124013.RAq5N_YZGEXU3dezvH3me854YkWYTRhMCzGwO3pYskKE8130_provenance.
- NP124023.RAuDKozMCtB29fzBpbMpJqTXkDl4WCASkH-VTWBEkf34Y130_assertion description "[CCND1 polymorphism is associated with an increased risk of endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124023.RAuDKozMCtB29fzBpbMpJqTXkDl4WCASkH-VTWBEkf34Y130_provenance.
- NP124035.RAnfiU0Zc4qs3nGza6XoKXONe0SZ5F4Jm6TEaTYQJ3xUQ130_assertion description "[MDR1 C3435T polymorphism is correlated with endometrial cancer susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124035.RAnfiU0Zc4qs3nGza6XoKXONe0SZ5F4Jm6TEaTYQJ3xUQ130_provenance.
- NP124039.RAgzIMSYtEb_61ZG0rwrYLdAHdd1LbikuOWkrK1izbVLA130_assertion description "[TCF4 expression mediated by beta-catenin/p300 may be important for initial steps during trans-differentiation of endometrial carcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124039.RAgzIMSYtEb_61ZG0rwrYLdAHdd1LbikuOWkrK1izbVLA130_provenance.
- NP124040.RAqfNkQp-CUEBNlL6SZUVTtCq6NXfQ62AAuy7V98Am-As130_assertion description "[A cellular mechanism underlying the linkages between endometrial cancer and obesity: adiponectin inhibits cell growth and induces apoptosis in human endometrial carcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124040.RAqfNkQp-CUEBNlL6SZUVTtCq6NXfQ62AAuy7V98Am-As130_provenance.
- NP124042.RAnm3yEOMLmkJZlRzTvL2vy_vgQBZnTWCBsACQzcH13D8130_assertion description "[DDR1 gene may be regarded as a potential marker for some types of endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124042.RAnm3yEOMLmkJZlRzTvL2vy_vgQBZnTWCBsACQzcH13D8130_provenance.
- NP124052.RAspflI5t3OeIJUxdFGZF52Z5k_1Hj00dORUcVDNMnq90130_assertion description "[MLH1 promoter methylation is associated with colorectal and endometrial carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124052.RAspflI5t3OeIJUxdFGZF52Z5k_1Hj00dORUcVDNMnq90130_provenance.
- NP124053.RAvunmPjpI6HhU2WGOUCOd6-ncof9wYbLymFKaEINY2yc130_assertion description "[An analysis of MMR genes may be useful for patients with endometrial cancer showing familial aggregation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124053.RAvunmPjpI6HhU2WGOUCOd6-ncof9wYbLymFKaEINY2yc130_provenance.
- NP124054.RApk2-eKyMys4xGFTT4xw3uJYuu410Nr3yJfADtZHxyeQ130_assertion description "[Development of endometrial carcinoma is associated with an overexpression of NDRG1 and the loss of PTEN expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124054.RApk2-eKyMys4xGFTT4xw3uJYuu410Nr3yJfADtZHxyeQ130_provenance.
- NP124058.RAn8v6vTTZrOnZ0xJbs2xIpL2VsZfbJq_mp-jPcfm0xSo130_assertion description "[both SF1 and LRH1 can transcriptionally cooperate with the AP-1 family members c-JUN and c-FOS, known to be associated with enhanced proliferation of endometrial carcinoma cells, to further enhance activation of the STAR, HSD3B2, and CYP19A1 PII promoters ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124058.RAn8v6vTTZrOnZ0xJbs2xIpL2VsZfbJq_mp-jPcfm0xSo130_provenance.
- NP124062.RAkuNR2UynmI_nJocEr5Bnr524YZ4vi3cT4Wn17iH3b08130_assertion description "[Activity of this enzyme in endometrial cancer obtained by tritium-labeled steroids.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124062.RAkuNR2UynmI_nJocEr5Bnr524YZ4vi3cT4Wn17iH3b08130_provenance.
- NP124063.RAtnZwk7UHJUvpSU_CZeNgpLuRqAtuc_5O19eaDOrQSnQ130_assertion description "[Increased steroid sulfatase expression is associated with estrogen-dependent endometrial carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124063.RAtnZwk7UHJUvpSU_CZeNgpLuRqAtuc_5O19eaDOrQSnQ130_provenance.
- NP124064.RAgSJtP2zWiqv9oyf-Uq8I1FkgQawBRw51MdN5oCqQRJY130_assertion description "[both SF1 and LRH1 can transcriptionally cooperate with the AP-1 family members c-JUN and c-FOS, known to be associated with enhanced proliferation of endometrial carcinoma cells, to further enhance activation of the STAR, HSD3B2, and CYP19A1 PII promoters ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124064.RAgSJtP2zWiqv9oyf-Uq8I1FkgQawBRw51MdN5oCqQRJY130_provenance.
- NP124073.RAixDnweRNTnf1D-NBbTRrA123qyjSSdoX3-rvG3oTnWA130_assertion description "[PTEN mutations are associated with endometrial carcinomas and hyperplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124073.RAixDnweRNTnf1D-NBbTRrA123qyjSSdoX3-rvG3oTnWA130_provenance.
- NP124076.RAsuC2ad_Su0J8bw_YGqJqyizHhf8Q6wjgOMJ7QqpV7iI130_assertion description "[results confirm that PIK3CA mutations are frequent in endometrial carcinoma and support the hypothesis that PIK3CA mutations may have an additive effect to PTEN monoallelic inactivation in endometrial carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124076.RAsuC2ad_Su0J8bw_YGqJqyizHhf8Q6wjgOMJ7QqpV7iI130_provenance.
- NP124082.RAu9MZQKetQP4kMFnSoO-jwSe3VUHfaUbkTKOs481lHkA130_assertion description "[polymorphism and risk of endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124082.RAu9MZQKetQP4kMFnSoO-jwSe3VUHfaUbkTKOs481lHkA130_provenance.
- NP124087.RAvP2ApTEBEfMn_Erowqc-ikP1nl65j7sM-KDH2FLrqDw130_assertion description "[dysregulated IGF and steroid hormone receptor signaling is prominent in endometrial benign stages and these alterations could represent clinical indicators for the risk of EnCa (endometrial carcinoma) and also help in development of new therapies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124087.RAvP2ApTEBEfMn_Erowqc-ikP1nl65j7sM-KDH2FLrqDw130_provenance.
- NP124090.RAgGsxBbgJR6yyuxBwa8hN5QDF-S3u_h5Y1GC-qChPFp4130_assertion description "[MGB-2 is highly expressed in endometrioid endometrial cancer [EEC], particularly in well- and moderately differentiated tumors, and may represent a novel molecular marker for EEC ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124090.RAgGsxBbgJR6yyuxBwa8hN5QDF-S3u_h5Y1GC-qChPFp4130_provenance.
- NP124092.RAuZihRU0ZCsg4DFfcgzZZMOC5m3d9V_RVSRYsXiPKvQY130_assertion description "[From a population database of BRCA1 and 2 mutation carriers in Southwestern Ontario, Canada, we identified three women with advanced-stage endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124092.RAuZihRU0ZCsg4DFfcgzZZMOC5m3d9V_RVSRYsXiPKvQY130_provenance.
- NP124094.RAsCnQD0JDIdWFERln75QDM45MKzdpfYPhII4eCs1oVEQ130_assertion description "[DNMT1 protein overexpression might contribute to aberrant DNA hypermethylation of specific tumor suppressor genes in endometrial cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124094.RAsCnQD0JDIdWFERln75QDM45MKzdpfYPhII4eCs1oVEQ130_provenance.
- NP124097.RAmOwXTE-IhQi1hbQyvDL92lG7bap2JPvi-ZrjH0EBPhU130_assertion description "[High p53 expression level with low MDM2 and p14 ARF levels may be the characteristic features of low differentiated endometrial carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124097.RAmOwXTE-IhQi1hbQyvDL92lG7bap2JPvi-ZrjH0EBPhU130_provenance.
- NP124105.RAokZ2wvNaYEw_HzwinIk-vdZdVj_VMKFlS9hkZKA0_yM130_assertion description "[COX-2 is upregulated in endometrial cancer and facilitates tumor growth via angiogenesis produced in associated with VEGF and TP ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124105.RAokZ2wvNaYEw_HzwinIk-vdZdVj_VMKFlS9hkZKA0_yM130_provenance.
- NP124111.RArC9mKvuVmbNxft3uSqqcIAhZVBKZ5ruQXgCw4hE7lyE130_assertion description "[more aggressive clinically and frequently receptor-negative type II of endometrial cancer is associated with excess of CYP19 A6A6 genotype ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124111.RArC9mKvuVmbNxft3uSqqcIAhZVBKZ5ruQXgCw4hE7lyE130_provenance.
- NP124114.RApkLCGGprPk1ZEaRAJbPHxIfEg-TWmf726Z-ejhh4fzk130_assertion description "[CYP19 genetic polymorphism is associated with endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124114.RApkLCGGprPk1ZEaRAJbPHxIfEg-TWmf726Z-ejhh4fzk130_provenance.
- NP124116.RAshRHjogGr_xFhA7bVVHflheRB-ibuluO7DLcDo3_tjo130_assertion description "[CYP17 genetic polymorphism in endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124116.RAshRHjogGr_xFhA7bVVHflheRB-ibuluO7DLcDo3_tjo130_provenance.
- NP124118.RAtQVLxbLg0IYfa3HpYQ93hmQ6KFepKPZznsGQl9aLQE4130_assertion description "[Overexpression of cyclooxygenase-2 correlates with tumor angiogenesis in endometrial carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124118.RAtQVLxbLg0IYfa3HpYQ93hmQ6KFepKPZznsGQl9aLQE4130_provenance.
- NP124120.RAolXzDNxKBaCU610RUzoQsBDm1Go3NcsGtLhVks0r1Mo130_assertion description "[COX-2, MMP-2 and MMP-9 were expressed in a high percentage of primary endometrial carcinomas and their expressions may be associated closely with parameters of tumor aggressiveness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124120.RAolXzDNxKBaCU610RUzoQsBDm1Go3NcsGtLhVks0r1Mo130_provenance.
- NP124122.RAgQWQU84ek5URI96tY0t4mAphXNf07oZGbbEGuNNHjOY130_assertion description "[COX-2 expression is an independent clinicopathologic factor and an independent prognostic factor in endometrial carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124122.RAgQWQU84ek5URI96tY0t4mAphXNf07oZGbbEGuNNHjOY130_provenance.
- NP124126.RAsnxZJuRDW9N227wp3LBC6d-oAaP21UpD7VzK1fmNNZM130_assertion description "[Overexpressiom of coxsackievirus and adenovirus receptor is associted with Endometrial Neoplasms ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124126.RAsnxZJuRDW9N227wp3LBC6d-oAaP21UpD7VzK1fmNNZM130_provenance.
- NP124129.RAgQ14g3Ztk6R2bJX771WnnRSSmY4CVl3ZxFbntg7ZePk130_assertion description "[The CAG repeats in exon 1 of the androgen receptor gene are longer in endometrial cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124129.RAgQ14g3Ztk6R2bJX771WnnRSSmY4CVl3ZxFbntg7ZePk130_provenance.
- NP124130.RAvbry2huvy-d9uAAI-fbdpR8ZVEcLcRxLctH38X0aj1k130_assertion description "[Our results indicate that Fas-mediated apoptosis is important for endometrial cycling and suggest that dysregulation of the Fas/FasL interactions may have an important role in the development of endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124130.RAvbry2huvy-d9uAAI-fbdpR8ZVEcLcRxLctH38X0aj1k130_provenance.
- NP124138.RArcVBRooIkQf4D43NkXtBzv1c8APeV13KR32Maz0S8F0130_assertion description "[DHT may play more important roles than testosterone in the regulation of androgen action in endometrial cancer and normal human endometrium, especially in the secretory phase, in which both AR and 5alpha-reductase are increased ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124138.RArcVBRooIkQf4D43NkXtBzv1c8APeV13KR32Maz0S8F0130_provenance.
- NP124139.RAimcCFDhykQ7PjrtZ_oZO_fM7RMB1BSvm8v36Ik9VYpc130_assertion description "[data suggests that short CAG or GGN repeats of the AR gene are associated with a more benign condition of traditional prognostic variables in endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124139.RAimcCFDhykQ7PjrtZ_oZO_fM7RMB1BSvm8v36Ik9VYpc130_provenance.
- NP124151.RAt-m1lnjffTWaFv_hPEmW1iHiIchB4Ew0MYYbeI8JA60130_assertion description "[These data also suggest that location of intragenic PTEN mutations and their coexistence with the CMYC amplification may play a crucial part in the development of various subtypes of endometrial carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124151.RAt-m1lnjffTWaFv_hPEmW1iHiIchB4Ew0MYYbeI8JA60130_provenance.
- NP124154.RAidewgZYqYVaMK4ccQo2V3zo9wH9AgQQbsorlFomhJA8130_assertion description "[MAP3K8 was found overexpressed in 30% of the endometrial carcinoma samples ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124154.RAidewgZYqYVaMK4ccQo2V3zo9wH9AgQQbsorlFomhJA8130_provenance.
- NP124166.RAvb832W9lEADw1MvW98y2h863pODBc7xTq8D1qVPNJV8130_assertion description "[KAI1 expression is down-regulated in advanced endometrial cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124166.RAvb832W9lEADw1MvW98y2h863pODBc7xTq8D1qVPNJV8130_provenance.
- NP124168.RAlxR_PfVGk5gVdIoc0yT4qP32UibvyosO3LoJ-orgbWY130_assertion description "[Findings suggested that the GSTP1 Ile (105) Val polymorphism was associated with an increased risk of endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124168.RAlxR_PfVGk5gVdIoc0yT4qP32UibvyosO3LoJ-orgbWY130_provenance.
- NP124170.RAvtUSFDAdAOc6xrzD77PXuEyhn9Vi20RHDy3WWm_k_Y0130_assertion description "[EMP2 may be a potential pharmacologic target for human endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124170.RAvtUSFDAdAOc6xrzD77PXuEyhn9Vi20RHDy3WWm_k_Y0130_provenance.
- NP124183.RAicOctBKzOYVQXt-Ug5NH8lkJrktjwmfHr13nHqez7uM130_assertion description "[PPARgamma is expressed in human endometrial carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124183.RAicOctBKzOYVQXt-Ug5NH8lkJrktjwmfHr13nHqez7uM130_provenance.
- NP124190.RApQs3758syXogz54uCfgD31MM25CuZaP3lszdl2y7xqc130_assertion description "[AIB1-Delta3 causes a significant increase in the efficacy of 17beta-estradiol at both estrogen receptor-alpha (ER-alpha) and ER-beta in ovarian, breast and endometrial cancer cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124190.RApQs3758syXogz54uCfgD31MM25CuZaP3lszdl2y7xqc130_provenance.
- NP124192.RApBmSc2TJnEJ4KP3Q12cB5yn7GlcFuh9sbRxd57MyVx8130_assertion description "[may be possible to use progestins to increase the response of endometrioid endometrial carcinoma with SLC22A16 expression to adriamycin-based chemotherapeutic regimens ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124192.RApBmSc2TJnEJ4KP3Q12cB5yn7GlcFuh9sbRxd57MyVx8130_provenance.
- NP124194.RAofcrO8QhufpV60cz7eeKGcmlIcaz13WpIR7846erXZs130_assertion description "[results showed a significant correlation between microvessel count and ets-1 gene expression levels in uterine endometrial cancers; localization of ETS-1 was similar to that of vascular endothelial cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124194.RAofcrO8QhufpV60cz7eeKGcmlIcaz13WpIR7846erXZs130_provenance.
- NP124198.RAp2wUyK45QdH855zX7opwQ_yFUr4Y1CTf9mNtvT9ue8E130_assertion description "[Mutations in SLC9A6 cause X-linked mental retardation; males with findings suggestive of unexplained Angelman syndrome should be considered as potential candidates for SLC9A6 mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124198.RAp2wUyK45QdH855zX7opwQ_yFUr4Y1CTf9mNtvT9ue8E130_provenance.
- NP124205.RArsPHYG5nsuldElnYPGe2n9_Oxs1KnBtaxI3ZAm__8sA130_assertion description "[data implicate SIZN1 as a candidate gene for X-linked mental retardation and/or as a neurocognitive functional modifier ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124205.RArsPHYG5nsuldElnYPGe2n9_Oxs1KnBtaxI3ZAm__8sA130_provenance.
- NP124207.RAtkfEin4b37SZj09TPyoECefOw0gSSjgPFyawp-Y2yMw130_assertion description "[A novel missense mutation c.836C > T of the PHF8 gene was identified in a Finnish family with multiple-affected male patients with X-linked mental retardation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124207.RAtkfEin4b37SZj09TPyoECefOw0gSSjgPFyawp-Y2yMw130_provenance.
- NP124214.RAu7EGnBYFx7dEelhbtH6TjLZNtBoAH9GrnQY3K-RTv2A130_assertion description "["...mechanisms underlying X-linked hypopituitarism are...being unravelled, with involvement of SOX3 in a pedigree with X-linked mental retardation...isol.growth hormone defic., and PHF6 in two siblings with Borjeson-F-Leahmann syndrome." p.1208 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124214.RAu7EGnBYFx7dEelhbtH6TjLZNtBoAH9GrnQY3K-RTv2A130_provenance.
- NP124216.RAl38G-hH2j-NMKafkUfNrjdLp-5-9C2CNtM070sNWca8130_assertion description "[Oligophrenin 1 mutations were found in 12% (2/17) of individuals with mental retardatin and known cerebellar anomalies and in 1% (2/196) of the X-linked mental retardation group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124216.RAl38G-hH2j-NMKafkUfNrjdLp-5-9C2CNtM070sNWca8130_provenance.
- NP124219.RArJDQOY42SVjAWQ7oUTLn8vz9stXarG1qDCfcQYkq0tA130_assertion description "[WNK3 lies within the critical linkage interval for several human monogenic disorders, including X-linked mental retardation/function of mammalian WNK3 kinase remains to be investigated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124219.RArJDQOY42SVjAWQ7oUTLn8vz9stXarG1qDCfcQYkq0tA130_provenance.
- NP124222.RAj99wTvlkH087vm-6LQy85ZnYTWBrnlf2A5cEHvzIOxE130_assertion description "[JARID1C appears to be one of the more frequently mutated genes in X-linked mental retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124222.RAj99wTvlkH087vm-6LQy85ZnYTWBrnlf2A5cEHvzIOxE130_provenance.
- NP124227.RAhX4lYno4mGjimapxkg57vd8X2liU_hhyLOHJyiwPTkI130_assertion description "[These findings implicate Mediator in epigenetic restriction of neuronal gene expression to the nervous system and suggest a pathologic basis for MED12-associated X-linked mental retardation involving impaired REST-dependent neuronal gene regulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124227.RAhX4lYno4mGjimapxkg57vd8X2liU_hhyLOHJyiwPTkI130_provenance.
- NP124232.RAs3sQIGiAEk1hXsdcHZZo_EupLY7gHBk9k13ukK1vfv0130_assertion description "[Identification of ZNF674 as the third X-linked mental retardation gene in this cluster may indicate a common role for these zinc-finger genes that is crucial to human cognitive functioning.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124232.RAs3sQIGiAEk1hXsdcHZZo_EupLY7gHBk9k13ukK1vfv0130_provenance.
- NP124245.RAh-XEt3QPXmiadscz7f3haMbvDzkcQGlMaXizMLWIFL8130_assertion description "[MRX81 maps to Xp11.2-Xq12 and may be involved in nonspecific X-linked mental retardation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124245.RAh-XEt3QPXmiadscz7f3haMbvDzkcQGlMaXizMLWIFL8130_provenance.
- NP124249.RAt7GVfvFnYGaCy6GQHWc3SII5sWePpdvxSLr3RN_Jmb4130_assertion description "[Mutations of the NXF5 gene is associated with X-linked mental retardation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124249.RAt7GVfvFnYGaCy6GQHWc3SII5sWePpdvxSLr3RN_Jmb4130_provenance.
- NP124258.RAjmoO_71qaQdcz64lWRA3EWY0U3cZCR_yk25JMOa45F8130_assertion description "[A common methylenetetrahydrofolate reductase (C677T) polymorphism is associated with low bone mineral density and increased fracture incidence after menopause: longitudinal data from the Danish osteoporosis prevention study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124258.RAjmoO_71qaQdcz64lWRA3EWY0U3cZCR_yk25JMOa45F8130_provenance.
- NP124259.RAgloBY5xC-ncg7r995jlVsbY0Eddr4a9iyfPQz-pI8MQ130_assertion description "[Hyperhomocysteinemia, a risk factor for thrombosis, recurrent miscarriages, and osteoporosis, might derive from acquired folate and vitamin B 12 deficiencies and from a C677T mutation in methylene-tetrahydrofolate reductase (MTHFR) gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124259.RAgloBY5xC-ncg7r995jlVsbY0Eddr4a9iyfPQz-pI8MQ130_provenance.
- NP124261.RAp40OlJGyoxHJIUDmOH5W4wJlbHDrzzfI8lWD3AiTPeI130_assertion description "[Association of polymorphisms with genetic susceptibility to osteoporosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124261.RAp40OlJGyoxHJIUDmOH5W4wJlbHDrzzfI8lWD3AiTPeI130_provenance.
- NP124268.RAnA96vLPc53lvT-PLazg3No41-Wil3_6u8YCzKPWG768130_assertion description "[This study showed a significant association between otosclerosis and the COL1A1 first intron Sp1 site/allelic frequency of the Sp1 site is very similar between otosclerosis and osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124268.RAnA96vLPc53lvT-PLazg3No41-Wil3_6u8YCzKPWG768130_provenance.
- NP124275.RArLKL84aDs1SW1a8Lmlf1h9OWiAHtN8DVREvudkfK8fI130_assertion description "[The present study demonstrates that hOAT4 variants can causing inter-individual variation in anionic drug uptake and, therefore, could be used as markers for certain diseases including osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124275.RArLKL84aDs1SW1a8Lmlf1h9OWiAHtN8DVREvudkfK8fI130_provenance.
- NP124283.RAtLjiBTuplXltBNe86KJmMImshMgYyVpwDPTTuOyn9bI130_assertion description "[variants may be related to genetic effects on bone mineral density and osteoporosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124283.RAtLjiBTuplXltBNe86KJmMImshMgYyVpwDPTTuOyn9bI130_provenance.
- NP124286.RAswWjw8RV7QzopzatGG7dKs4jLDFB4XTMMvm0Nj4hJAM130_assertion description "[a region on the short arm of Chromosome 20 contains a gene or genes that appear to be a major risk factor for osteoporosis and osteoporotic fractures, including BMP2 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124286.RAswWjw8RV7QzopzatGG7dKs4jLDFB4XTMMvm0Nj4hJAM130_provenance.
- NP124292.RAjv_uYn2dizd3iIb-Kjgn4YZ9wYwXa8QN5e0fWvVDU78130_assertion description "[The possible involvement of vitamin D receptor gene polymorphisms in rheumatoid arthritis and associated osteoporosis was investigated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124292.RAjv_uYn2dizd3iIb-Kjgn4YZ9wYwXa8QN5e0fWvVDU78130_provenance.
- NP124297.RAucSW0iBw5nMjEbWYSqFQQKlIla8pvUnZXzFjG_DERrs130_assertion description "[Two gene variants of key biological proteins increase the risk of osteoporosis and osteoporotic fracture.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124297.RAucSW0iBw5nMjEbWYSqFQQKlIla8pvUnZXzFjG_DERrs130_provenance.
- NP124300.RAojZVUpyofH8y5OclbSi5uFcP90sRX2MoL-fNSviriX8130_assertion description "[SOST-LRP5 antagonistic interaction plays a central role in bone mass regulation and may represent a nodal point for therapeutic intervention for osteoporosis and other bone diseases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124300.RAojZVUpyofH8y5OclbSi5uFcP90sRX2MoL-fNSviriX8130_provenance.