Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP124738.RAjq-OxMU92Q1mGTRGpG91CcVYWz3KLARQhQVgq8uzhrU130_assertion description "[A four-marker panel of CA-125, macrophage chemotactic protein-1, leptin, and macrophage migration inhibitory factor could diagnose the presence of endometriosis with 93% accuracy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124738.RAjq-OxMU92Q1mGTRGpG91CcVYWz3KLARQhQVgq8uzhrU130_provenance.
- NP124741.RAh0ZF3fegWELPMMsDil3KrGs-OVCJHulOO1V3JEZWP6g130_assertion description "[in patients with endometriosis a significant negative correlation was observed between luminal expression of eNOS and alpha (v) beta (3) integrin and between glandular expression of eNOS and luminal expression of alpha (v) beta (3) integrin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124741.RAh0ZF3fegWELPMMsDil3KrGs-OVCJHulOO1V3JEZWP6g130_provenance.
- NP124743.RAsMhtf1lCreH_Mtzsa76bmljMhNL2TaRwV-dPNGiegWg130_assertion description "[Proportion of noncarriers of AHSG 2 allele significantly higher in women with endometriosis than in women without/not carrying AHSG 2 allele were found to have twice the risk of endometriosis than those carrying at least one copy of this allele.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124743.RAsMhtf1lCreH_Mtzsa76bmljMhNL2TaRwV-dPNGiegWg130_provenance.
- NP124745.RAmlpVTMlp8ji1AVrlOZDL4rAKOE7lb6AYcV7z5jfPiYI130_assertion description "[results suggest that the peroxisome proliferative activated receptor-gamma 161CC genotype could be a genetic risk factor for adenomyosis and endometriosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124745.RAmlpVTMlp8ji1AVrlOZDL4rAKOE7lb6AYcV7z5jfPiYI130_provenance.
- NP124747.RAkTVCS7WeUfaxpgonGAHN7AwJa61kltL5wbrWU6VcbPc130_assertion description "[the AhRR codon 185 and GSTT1 polymorphisms are associated with the risk of advanced stage endometriosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124747.RAkTVCS7WeUfaxpgonGAHN7AwJa61kltL5wbrWU6VcbPc130_provenance.
- NP124750.RAqRG6tNqGC8NWhcorsJtlw7vy66ayzY-HAwzEk4QwPz0130_assertion description "[may play a role in the pathogenesis of endometriosis, possibly by chemoattraction and activation of neutrophils present in higher numbers in the peritoneal fluid of women with endometriosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124750.RAqRG6tNqGC8NWhcorsJtlw7vy66ayzY-HAwzEk4QwPz0130_provenance.
- NP124752.RAqYI42HporycJFHZzhpfvlrldMd9nIVdxS2ISQJlQVkE130_assertion description "[Higher levels of leptin were observed in peritoneal fluid of patients with endometriosis compared to those without the disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124752.RAqYI42HporycJFHZzhpfvlrldMd9nIVdxS2ISQJlQVkE130_provenance.
- NP124754.RAgaOzRghYBTRxG6xNMUB95n5cWXswQGkCiWas1QWSWP0130_assertion description "[the differential distribution of mRNA for leptin and its receptor suggests an important autocrine and paracrine role for leptin in human endometriosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124754.RAgaOzRghYBTRxG6xNMUB95n5cWXswQGkCiWas1QWSWP0130_provenance.
- NP124757.RAkEXU_wH4G6uYF4A90puYUZGrmCqbBnfvX_KbkAObRi4130_assertion description "[Abnormally high levels of ERK1/2 activity may be involved in endometriosis, possibly by stimulating endometrial cell survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124757.RAkEXU_wH4G6uYF4A90puYUZGrmCqbBnfvX_KbkAObRi4130_provenance.
- NP124763.RAlIYP642Gk878Oho7ywiLVLwH0dhU-ZSfWEMNFeewQmM130_assertion description "[Results suggest that hSMR3A can act as a marker for erectile dysfunction associated with both diabetic and non-diabetic etiologies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124763.RAlIYP642Gk878Oho7ywiLVLwH0dhU-ZSfWEMNFeewQmM130_provenance.
- NP124771.RAlADi3lhoumzJtRcIq0Bf-qE5sf92JeJmIpQmjTl26zk130_assertion description "[We report a Chinese girl diagnosed with Laron syndrome at age 1.9 years with height -4.9 SDS, basal GH 344 mIU/ml, IGF-I < 12 ng/ml, IGFBP-3 < 0.2 mg/ml, and undetectable GHBP/novel mutation of the GHR was identified at the donor splice site of intron 6.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124771.RAlADi3lhoumzJtRcIq0Bf-qE5sf92JeJmIpQmjTl26zk130_provenance.
- NP124777.RAt0AGbHmOvk_Hy3Cfj37O3i8V8hErUkRCoUq9dXBbgt8130_assertion description "[Chemotherapy-induced overexpression of integrin b1 in some multiple myeloma patients upregulates LRP expression in bone marrow cells, inducing antineoplastic drug resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124777.RAt0AGbHmOvk_Hy3Cfj37O3i8V8hErUkRCoUq9dXBbgt8130_provenance.
- NP124779.RAvJF0DgfFZj8Ib1azWa6nClQJ68aAoHRPZ52rCYsrY0M130_assertion description "[DKK1 may play a key role in the development of osteolytic bone lesions in multiple myeloma by directly interrupting Wnt3a-regulated differentiation of osteoblasts ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124779.RAvJF0DgfFZj8Ib1azWa6nClQJ68aAoHRPZ52rCYsrY0M130_provenance.
- NP124782.RAqGIj6r-5BYJkE5DzI2sFLyGoQGO3R2rqKq3Niqq7IIM130_assertion description "[myeloma cells are the main source of circulating DKK-1 protein and provide a framework for clinical trials on anti-DKK-1 treatment in multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124782.RAqGIj6r-5BYJkE5DzI2sFLyGoQGO3R2rqKq3Niqq7IIM130_provenance.
- NP124789.RAhDKC4-lU0z4oVwjXjiTcTmCBKQF985qCkgmyKOa2HyU130_assertion description "[interleukin-11 receptor is expressed in CD38-positive cells from patients with multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124789.RAhDKC4-lU0z4oVwjXjiTcTmCBKQF985qCkgmyKOa2HyU130_provenance.
- NP124790.RAuUseMxwPVyPjyj-xVzpyNLVjw5LV-FeYV4VLEUYxhlg130_assertion description "[Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124790.RAuUseMxwPVyPjyj-xVzpyNLVjw5LV-FeYV4VLEUYxhlg130_provenance.
- NP124791.RAvgGz27YDiSr8g22MWhTlsjXEvCNVBRX1Zc6Pi0rVzqI130_assertion description "[These findings suggest that combined NFkappaB and STAT3 targeting can overcome apoptosis resistance of multiple myeloma cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124791.RAvgGz27YDiSr8g22MWhTlsjXEvCNVBRX1Zc6Pi0rVzqI130_provenance.
- NP124794.RAhuwghoCSgZrWIkyAxHpNt9mX0H1VES7QU1RvVacjomw130_assertion description "[The role of interleukin-6 in the development of functionally defective dendritic cells in multiple myeloma.IL-6 inhibited the colony growth of CD34 (+) DC progenitors and switched the commitment of CD34 (+) cells from DCs to monocytic cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124794.RAhuwghoCSgZrWIkyAxHpNt9mX0H1VES7QU1RvVacjomw130_provenance.
- NP124801.RAgWp76yTNZNPAG3bTiHh3hpoCHxA4HKlovFWGWgdOcbQ130_assertion description "[Immunohistochemical localization of phosphorylated AKT/PKB in multiple myeloma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124801.RAgWp76yTNZNPAG3bTiHh3hpoCHxA4HKlovFWGWgdOcbQ130_provenance.
- NP124802.RAp9MOJ7D-gMTUlULxAEARIiO9WygKkTxabsrzPi4-rE8130_assertion description "[the HGF-activator has a role in multiple myeloma cells'catalysis of hepatocyte growth factor (HGF) activation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124802.RAp9MOJ7D-gMTUlULxAEARIiO9WygKkTxabsrzPi4-rE8130_provenance.
- NP124809.RAvqZdKBVh4CQmOyj5DOd44gQz3Qr8-DUFU7tPgn1L2HU130_assertion description "[KIT expression is a rare event in multiple myeloma and not detectable in monoclonal gammopathy of undetermined significance and lymphoplasmacytic lymphoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124809.RAvqZdKBVh4CQmOyj5DOd44gQz3Qr8-DUFU7tPgn1L2HU130_provenance.
- NP124810.RAsrncFw4XPnCqtdREg4oBUCgFuXwjjBXLsl7uHJW2UN4130_assertion description "[c-Kit expression in multiple myeloma cells is functional, and coupled to survival pathways that may modulate cell death in response to therapeutic compounds used in the treatment of this disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124810.RAsrncFw4XPnCqtdREg4oBUCgFuXwjjBXLsl7uHJW2UN4130_provenance.
- NP124817.RAkD8PDbyrI24V_hRYyggdbsR1dwbOa8T49VaJS-6Q8Vg130_assertion description "[There is a somatic hypermutation of this gene in B-cell lymphoma and multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124817.RAkD8PDbyrI24V_hRYyggdbsR1dwbOa8T49VaJS-6Q8Vg130_provenance.
- NP124821.RAsz7L5tiG7LlQbh1OFEJDcNIpFhRBkxGp-Booj6lt6rI130_assertion description "[serum levels of BAFF and APRIL were increased about 5-fold in patients with multiple myeloma as compared with healthy donors ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124821.RAsz7L5tiG7LlQbh1OFEJDcNIpFhRBkxGp-Booj6lt6rI130_provenance.
- NP124824.RAmbm4kA-72KfYJJYfCKLbDpKNcPX5YepzJAZ6XjLjbC8130_assertion description "[Expressed in multiple myeloma cells and in bone marrow cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124824.RAmbm4kA-72KfYJJYfCKLbDpKNcPX5YepzJAZ6XjLjbC8130_provenance.
- NP124825.RAlL5jx2M8wvfj5iV39rD_obWHVznYp7BdzRAeNvT2IwA130_assertion description "[IL-6r and TNF-alpha increase in parallel to VEGF and FGF-2 with increasing stage of multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124825.RAlL5jx2M8wvfj5iV39rD_obWHVznYp7BdzRAeNvT2IwA130_provenance.
- NP124830.RAjnKJv2au5jpzTcSMxm-5X-vV-2GvYH7SBOJ-6qCgrIM130_assertion description "[determined the clinical characteristics of 204 multiple myeloma (MM) patients and 26 plasma cell leukemia (PCL) patients with regard to CD56 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124830.RAjnKJv2au5jpzTcSMxm-5X-vV-2GvYH7SBOJ-6qCgrIM130_provenance.
- NP124831.RAoux79D12RUZu-L3oU2BJO5pGe0X_7NK7gdHq2MsQx8A130_assertion description "[REVIEW: Prognostic significance of CD56 expressed in multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124831.RAoux79D12RUZu-L3oU2BJO5pGe0X_7NK7gdHq2MsQx8A130_provenance.
- NP124844.RArYFRYhI376PIWRW8q0jgrrmTG91akHzQdf3NpxXBpkY130_assertion description "[CD9 expression by multiple myeloma cells is upregulated in vivo by close interaction of the cells with endothelial cells and CD9 is involved in transendothelial invasion ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124844.RArYFRYhI376PIWRW8q0jgrrmTG91akHzQdf3NpxXBpkY130_provenance.
- NP124848.RAh7DqfntcgYnHjU4drrxKF3L7cG7Dp633k78XtyXg96g130_assertion description "[Oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124848.RAh7DqfntcgYnHjU4drrxKF3L7cG7Dp633k78XtyXg96g130_provenance.
- NP124850.RApzlwOz1kjoA2Og7vclENCpiw380qkeQ8eD8CIRaStQM130_assertion description "[data presented argue against a role for BCRP in primary drug resistance in multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124850.RApzlwOz1kjoA2Og7vclENCpiw380qkeQ8eD8CIRaStQM130_provenance.
- NP124852.RAvs1BCXbbnCF7jmkRvX373KIny35Ng2ghFCbCrhZ_2_Q130_assertion description "[multiple myeloma patients without osteonecrosis of the jaw and control subjects presented similar values of IL-17 serum levels ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124852.RAvs1BCXbbnCF7jmkRvX373KIny35Ng2ghFCbCrhZ_2_Q130_provenance.
- NP124854.RArl0bLV-Hz5MRwL2sFTR8XeR1bdtPs3Vs6pqAXqJ4FyM130_assertion description "[serum level of (IL) -16 was significantly higher in stage III multiple myeloma patients than in healthy controls/decrease of CD4 (+) T cells in MM may be mediated by activation of CD8 (+) T cells derived cytokine IL-16.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124854.RArl0bLV-Hz5MRwL2sFTR8XeR1bdtPs3Vs6pqAXqJ4FyM130_provenance.
- NP124856.RAj2Cl2nFAagJMbMTYYZ07Dse-bAMnGddDjcWiPe8vHL8130_assertion description "[IL-12R beta 2 directly restrains multiple myeloma cell growth ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124856.RAj2Cl2nFAagJMbMTYYZ07Dse-bAMnGddDjcWiPe8vHL8130_provenance.
- NP124860.RAv0ShfBAy6wjxkAVRjbv7PVUPuOGNnNnJMMh9kcp6Cfk130_assertion description "[Isolated from multiple myeloma patients, this protein in crystal form may shed some light on the formation of fibrils common to certain storage diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124860.RAv0ShfBAy6wjxkAVRjbv7PVUPuOGNnNnJMMh9kcp6Cfk130_provenance.
- NP124861.RAqHKb1T4e6NpDFX-485dwbxK9R9qBStQbOhMDW3JcgpI130_assertion description "[High calcitonin receptor is associated with multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124861.RAqHKb1T4e6NpDFX-485dwbxK9R9qBStQbOhMDW3JcgpI130_provenance.
- NP124863.RAjtZcR8-pId-VSwmbKsj-V-pEDIjmWK4EfPvGTFTyZjo130_assertion description "[PCNA expression in bone marrow plasma cells constitutes a good prognostic indicator of disease activity in patients with multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124863.RAjtZcR8-pId-VSwmbKsj-V-pEDIjmWK4EfPvGTFTyZjo130_provenance.
- NP124869.RAhUz23yuHPRDpw9ZJJXiGxqJe_8n4UwfPtotE4yIdNCg130_assertion description "[Met is expressed by the majority of MM cell lines and by approximately half of the primary plasma cell neoplasms tested.The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124869.RAhUz23yuHPRDpw9ZJJXiGxqJe_8n4UwfPtotE4yIdNCg130_provenance.
- NP124870.RAtXFM7nGiJ4ccNGx5M9DS32jCsUyYjK4FNXsAb_q1I6I130_assertion description "[Normal human plasma cells have significantly lower levels of PRDI-BF1beta expression than plasma cells isolated from multiple myeloma patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124870.RAtXFM7nGiJ4ccNGx5M9DS32jCsUyYjK4FNXsAb_q1I6I130_provenance.
- NP124871.RAhLLzF-C5ltqw8ueu7m63GLNTguoxR4W8HuauOePDNoo130_assertion description "[May be a biological markers of bone disease in multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124871.RAhLLzF-C5ltqw8ueu7m63GLNTguoxR4W8HuauOePDNoo130_provenance.
- NP124872.RAko9VRT6ZYBlg_8scRx2d_bOWqrdMJZLusZ_LllbzAEY130_assertion description "[Ursolic acid is a novel blocker of STAT3 activation that may have a potential in prevention and treatment of multiple myeloma and other cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124872.RAko9VRT6ZYBlg_8scRx2d_bOWqrdMJZLusZ_LllbzAEY130_provenance.
- NP124873.RAlSjmqxb9IYtAs3iiLf3ezvDavL3tOxDTCQ4UlcF9lZM130_assertion description "[ubiquitylation and degradation by mumps virus V protein prevents responses to interleukin-6 and v-Src signals and can induce apoptosis in STAT3-dependent multiple myeloma cells and transformed murine fibroblasts ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124873.RAlSjmqxb9IYtAs3iiLf3ezvDavL3tOxDTCQ4UlcF9lZM130_provenance.
- NP124888.RAj3nKTcTjzSYWhJaMrC7NhQjo9eXpChYwMoa8hKLjmQ4130_assertion description "[Inhibition of p38 MAPK inhibits IL-6 and VEGF secretion in bone marrow stromal cells triggered by adherence of multiple myeloma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124888.RAj3nKTcTjzSYWhJaMrC7NhQjo9eXpChYwMoa8hKLjmQ4130_provenance.
- NP124889.RAt0C_xCQvhajUO46RJ6NBGgq9m4M2taF75Acb2bt4TIw130_assertion description "[Cultured plasma cells from patients with advanced relapsed/refractory multiple myeloma who responded favorably to thalidomide secreted a significantly lower amount of VEGF than did plasma cells from resistant patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124889.RAt0C_xCQvhajUO46RJ6NBGgq9m4M2taF75Acb2bt4TIw130_provenance.
- NP124890.RArHn5gMrGwAzuvO29oG2vPUtBNC9z-1nIJxRjmbbyxsw130_assertion description "[Progression of multiple myeloma to a vascular phase is accompanied by increase in microcirculation and and in VEGF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124890.RArHn5gMrGwAzuvO29oG2vPUtBNC9z-1nIJxRjmbbyxsw130_provenance.
- NP124893.RAhWcg9baFLN9RW2cMw8c9IXGIyvhOTIFhAJGw3QDtZeI130_assertion description "[A paracrine loop in the VEGF pathway triggers tumor angiogenesis and growth in multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124893.RAhWcg9baFLN9RW2cMw8c9IXGIyvhOTIFhAJGw3QDtZeI130_provenance.
- NP124894.RAlw_HF-e3LIzJxWTlwvljG86waSDYJuEWm-2_Gb4Ilac130_assertion description "[CS1 was expressed at adhesion-promoting uropod membranes of polarized Multiple Myeloma cells, andis required for MM cell adhesion to bone marrow stromal cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124894.RAlw_HF-e3LIzJxWTlwvljG86waSDYJuEWm-2_Gb4Ilac130_provenance.
- NP124899.RAu_DaLxFBQsOWesl1QW_2hbWfUI-Q4iNVM75uhnrbMlg130_assertion description "[no significant associations were observed with disease stages, disease status, osteolytic lesions, and survival of patients with multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124899.RAu_DaLxFBQsOWesl1QW_2hbWfUI-Q4iNVM75uhnrbMlg130_provenance.
- NP124901.RAo3aka78u4LnakhN9B2VqVwXQT_LY_ItiUD8qRKXCGCU130_assertion description "[role in regulation of MIP-1 alpha expression in multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124901.RAo3aka78u4LnakhN9B2VqVwXQT_LY_ItiUD8qRKXCGCU130_provenance.
- NP124907.RAitpQoBwKEy-6GxmhasBbdOzn418DGwNjx2N0kYcPoJg130_assertion description "[Levels of IL-1beta high or low activity in myeloma cell lines define groups of patients with smoldering multiple myeloma (MM): high producers are similar to patients with active MM; low producing levels resemble those with benign monoclonal gammopathies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124907.RAitpQoBwKEy-6GxmhasBbdOzn418DGwNjx2N0kYcPoJg130_provenance.
- NP124909.RAveluEk584WKy9yrbygBj7j4EeC2HLdzO-hizwYLrpgI130_assertion description "[JAK2V617F-positive essential thrombocythemia and multiple myeloma with IGH/CCND1 gene translocation coexist, but originate from separate clones ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124909.RAveluEk584WKy9yrbygBj7j4EeC2HLdzO-hizwYLrpgI130_provenance.
- NP124910.RAonMn2XbA_wObmCpv28igwJg_Y6CzD6Y5YUusY7blPMU130_assertion description "[insulin-like growth factor-I increased invasion activity in ARK5-mRNA expressing multiple myeloma cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124910.RAonMn2XbA_wObmCpv28igwJg_Y6CzD6Y5YUusY7blPMU130_provenance.
- NP124913.RAnUPiW3zi2UfURg4LB1PojYbZz6v7g6Gb0fDWh7Hv6tg130_assertion description "[Data indicate that serum endostatin levels are higher in multiple myeloma patients than in healthy controls, with the highest values found during the active phase of the disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124913.RAnUPiW3zi2UfURg4LB1PojYbZz6v7g6Gb0fDWh7Hv6tg130_provenance.
- NP124914.RAsbwdZ7niZ2D1F5mkKhRyXYbPW5XrHH2aRHM42wxN16g130_assertion description "[The activation of signal transducer and activator of transcription 3 (Stat3) is obligatory for the survival of INA-6 multiple myeloma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124914.RAsbwdZ7niZ2D1F5mkKhRyXYbPW5XrHH2aRHM42wxN16g130_provenance.
- NP124919.RApQ3s9cIWUEBUjRsX8N3MlfD78aSIabutLe4__unK8R0130_assertion description "[Transgenic mice crrossed with c-MYC transgenic mice develop multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124919.RApQ3s9cIWUEBUjRsX8N3MlfD78aSIabutLe4__unK8R0130_provenance.
- NP124920.RAu0uEpg0TlR53E6ch-Oe3NUCcm3hULW8cbvHySN193AU130_assertion description "[Presence in bone marrow cells indicated diagnosis of multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124920.RAu0uEpg0TlR53E6ch-Oe3NUCcm3hULW8cbvHySN193AU130_provenance.
- NP124929.RAgS7o1pZlZG0vPKpuThj3_8uX6Oj16Uvat5PNLk-W4Jc130_assertion description "[bound, internalized, and degraded by multiple myeloma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124929.RAgS7o1pZlZG0vPKpuThj3_8uX6Oj16Uvat5PNLk-W4Jc130_provenance.
- NP124930.RAo1zLVMdSuALV1OP3wi6x7SpspycS9mkXFksqD3LDibU130_assertion description "[hypermethylated in multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124930.RAo1zLVMdSuALV1OP3wi6x7SpspycS9mkXFksqD3LDibU130_provenance.
- NP124938.RArlPLpl5wIJGjMWSwQTpJPN__vxUoqsrvFhfGWpyCuKo130_assertion description "[In 60 multiple myeloma patients checked, it was found that among the Wnt inhibitors, Dickkopf-1 and secreted frizzled-related protein-3 were produced by multiple myeloma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124938.RArlPLpl5wIJGjMWSwQTpJPN__vxUoqsrvFhfGWpyCuKo130_provenance.
- NP124943.RAoRTTS3LyNrcDC7cdD3ys_HOve3ABZNm4zy3M07PfdjI130_assertion description "[Allelic distribution of the +252 A > G promoter polymorphism of the LT-alpha gene was determined in multiple myeloma patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124943.RAoRTTS3LyNrcDC7cdD3ys_HOve3ABZNm4zy3M07PfdjI130_provenance.
- NP124946.RAtAA48w6IsNk3Eafm2N8egpQQ0Pu7Z6qx1ac1-bA1SbQ130_assertion description "[difference in sensitivity to stress stimuli and IL6-induced cell growth between CD45+ and CD45- multiple myeloma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124946.RAtAA48w6IsNk3Eafm2N8egpQQ0Pu7Z6qx1ac1-bA1SbQ130_provenance.
- NP124964.RAg_wIBlWLru3jAHMHZIWOCsQFx1z1PI9sZZ30DI4jyMI130_assertion description "[Noxa expression was enhanced by GSH depletion and inhibited by increasing GSH levels in the multiple myeloma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124964.RAg_wIBlWLru3jAHMHZIWOCsQFx1z1PI9sZZ30DI4jyMI130_provenance.
- NP124965.RAmNr1irnTAJbdUwAs0f2-PvoKE85L0ttE8YTgYOA4jZE130_assertion description "[HLA-B-associated transcript 3 (BAT3) was released from tumor cells, bound directly to NKp30, and engaged NKp30 on NK cells/triggered NKp30-mediated cytotoxicity and was necessary for tumor rejection in a multiple myeloma model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124965.RAmNr1irnTAJbdUwAs0f2-PvoKE85L0ttE8YTgYOA4jZE130_provenance.
- NP124973.RAvspS9FF5PuITTLM6_HYp67M21dLb3I7uXooQsPG8_3g130_assertion description "[disruption of Smad2 function by CDK2 phosphorylation acts as a mechanism for TGF-beta resistance in multiple myeloma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124973.RAvspS9FF5PuITTLM6_HYp67M21dLb3I7uXooQsPG8_3g130_provenance.
- NP124979.RAt8pSkCiSt8IommeANz8AVAioOugNxAMCYRQsuRwjQag130_assertion description "[CD40 activation induces p53-dependent VEGF secretion and cell migration in multiple myeloma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124979.RAt8pSkCiSt8IommeANz8AVAioOugNxAMCYRQsuRwjQag130_provenance.
- NP124980.RAqyZro7-BvhTvY7xFrONV_r_E94p9fxoVkao3250s1P8130_assertion description "[Validation of TIMP-1 expression in human lymphoma cell lines and primary B-cell tumors with plasmacytic/plasmablastic phenotypes, including multiple myelomas, supports TIMP-1 as an important factor in the pathogenesis of plasmacytic/plasmablastic tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124980.RAqyZro7-BvhTvY7xFrONV_r_E94p9fxoVkao3250s1P8130_provenance.
- NP124989.RAgaY6kgbb2ll7AoTs8m28d_yG7tWrdEy_S1MWmmFjoOo130_assertion description "[Promoter polymorphisms of FCGR2A, FCGR3A and FCGR3B were not convincingly associated with infections after chemotherapy and stem cell transplantation in multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP124989.RAgaY6kgbb2ll7AoTs8m28d_yG7tWrdEy_S1MWmmFjoOo130_provenance.
- NP125000.RAqej4KYGJlg38KWTg5BRBd1HTFgkZNlfAz9yQIcPj5Gs130_assertion description "[data indicate that t (4; 14) (p16; q32) and loss of fibroblast growth factor receptor 3 occurred at a very early stage of multiple myeloma and suggest that activation of multiple myeloma SET domain protein may be transforming event of this translocation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125000.RAqej4KYGJlg38KWTg5BRBd1HTFgkZNlfAz9yQIcPj5Gs130_provenance.
- NP125012.RAp9Sqk2sKjs8h56IwQLdbpmTZT-ZvXLqPezFd2-7NCis130_assertion description "[involvement of ABCG2 in multidrug resistance in cancer, especially with regard to acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125012.RAp9Sqk2sKjs8h56IwQLdbpmTZT-ZvXLqPezFd2-7NCis130_provenance.
- NP125025.RAjBhdAkmSw_8AWembm8ajuLgRS-VObhjeR4zBmf8IbAI130_assertion description "[The expression of mRNA for MDR1 and LRP was determined in bone marrow samples from control, de novo acute myelocytic leukemia, myelodysplastic syndrome (MDS), MDS at the time of overt leukemia (OL) transformation (MDS -- > OL), and after transformation (OL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125025.RAjBhdAkmSw_8AWembm8ajuLgRS-VObhjeR4zBmf8IbAI130_provenance.
- NP125026.RAieZziT4tvuOCA2PUrLxXbkkLEuSsyZG-Vzfg_bKOH20130_assertion description "[Determination of P-glycoprotein, MDR-related protein 1, breast cancer resistance protein, and lung-resistance protein expression in leukemic stem cells of acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125026.RAieZziT4tvuOCA2PUrLxXbkkLEuSsyZG-Vzfg_bKOH20130_provenance.
- NP125028.RAoMuOL9gbAIdwilIsSK6BL-zSGBi-f42jjpgz_X08-vg130_assertion description "[BCRP was over-expressed in 24 patients and was significantly co-expressed with P-glycoprotein in acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125028.RAoMuOL9gbAIdwilIsSK6BL-zSGBi-f42jjpgz_X08-vg130_provenance.
- NP125029.RAiR89JphYsAOp9MbkpzJA_VYjENS3J-PAnxSEP4rhKso130_assertion description "[In four different groups of marrow samples (20 normal, 56 acute myeloid leukemias (AML) at diagnosis, 48 AMLs at relapse, and 51 regenerating marrows), caveolin-1 and MDR-1 gene expressions were positively correlated ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125029.RAiR89JphYsAOp9MbkpzJA_VYjENS3J-PAnxSEP4rhKso130_provenance.
- NP125030.RArZeIsdgf4vqm7lzv3le0Vh7qwKXvi3eTSXYfAdpAlUs130_assertion description "[novel mutations in c-CBL and CBL-b have been identified in human acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125030.RArZeIsdgf4vqm7lzv3le0Vh7qwKXvi3eTSXYfAdpAlUs130_provenance.
- NP125035.RAj_nFtHkeEwRmS01uV1lA_tcr2cWi6CySVGC_ypg1T-Q130_assertion description "[transcription mediated by AML1 is impaired by mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125035.RAj_nFtHkeEwRmS01uV1lA_tcr2cWi6CySVGC_ypg1T-Q130_provenance.
- NP125042.RAkOv1jSpX3kCsI1JRSs7PnJrtG1APYlrnRWZzhh91hls130_assertion description "[RUNX1 may have a role in lineage conversion of childhood B-cell acute lymphoblastic leukemia to acute myelogenous leukemia [case report]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125042.RAkOv1jSpX3kCsI1JRSs7PnJrtG1APYlrnRWZzhh91hls130_provenance.
- NP125045.RAt_9Fz9qCW96XF4wV8CiKBWArx7BQFlU_jI3gBVK0bwU130_assertion description "[reduced AML1 activities predispose cells to the acquisition of the activating FLT3 mutation as a secondary event leading to full transformation in acute myeloblastic leukemia M0.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125045.RAt_9Fz9qCW96XF4wV8CiKBWArx7BQFlU_jI3gBVK0bwU130_provenance.
- NP125049.RAk-iU62KoyMoNS_tWfBZbTsklFTiFXDNyhTWzntaPew8130_assertion description "[REVIEW: Familial mutations predispose to acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125049.RAk-iU62KoyMoNS_tWfBZbTsklFTiFXDNyhTWzntaPew8130_provenance.
- NP125059.RAtH-fYjAPoqJtRGlpm8LBit0nOb8c7yyhd4itqaQ4XDE130_assertion description "[homozygous CEBPA mutations in acute myeloid leukemia may be due to segmental uniparental disomy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125059.RAtH-fYjAPoqJtRGlpm8LBit0nOb8c7yyhd4itqaQ4XDE130_provenance.
- NP125062.RAn4TfaUfi8K4O-J7zlZ_81qkVr1mZbkwZ0gjee0oMPCk130_assertion description "[Mutation of CEBPA is a recurrent finding in acute myeloid leukemia FAB type M1 and M2 and appears specific to the intermediate cytogenetic risk group patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125062.RAn4TfaUfi8K4O-J7zlZ_81qkVr1mZbkwZ0gjee0oMPCk130_provenance.
- NP125063.RAp-1s9_TKw3tkysOyIww_OFX-L5RFEVjWKTczUgqrD8Q130_assertion description "[The emergence of a mutation in this protein is involved in the clonal evolution of myelodysplastic syndromes towards secondary acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125063.RAp-1s9_TKw3tkysOyIww_OFX-L5RFEVjWKTczUgqrD8Q130_provenance.
- NP125066.RApQq5eYlhvQJabGT1vieo-42LLFz3qr7hOm5E4bBd7UQ130_assertion description "[CAMLG was more frequently significantly overexpressed in acute myeloid leukemia patients with CD56 immunophenoytpe ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125066.RApQq5eYlhvQJabGT1vieo-42LLFz3qr7hOm5E4bBd7UQ130_provenance.
- NP125067.RAvUUuu26hZySb6Uoy-zlx30YbE883Jr0wNaqBBQ_Mjdo130_assertion description "[Haploinsufficiency for Egr1plays a role in the development of acute myeloid leukemia and myelodysplastic syndromes characterized by abnormalities of chromosome 5.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125067.RAvUUuu26hZySb6Uoy-zlx30YbE883Jr0wNaqBBQ_Mjdo130_provenance.
- NP125074.RApMC1sxeLNaY92D3tnk_ADz2ma92Gey1SVjxvgBPLx-A130_assertion description "[GAB2 is a novel target of 11q amplification in acute myeloid leukemia and myelodysplastic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125074.RApMC1sxeLNaY92D3tnk_ADz2ma92Gey1SVjxvgBPLx-A130_provenance.
- NP125076.RAsnG_6BpSEPTvi92HP8a-r16Cj425l-hnEdPV9cDXrnI130_assertion description "[Sustained expression of nucleophosmin (NPM1) mutation at late relapse presenting as isolated myeloid sarcoma in a patient with acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125076.RAsnG_6BpSEPTvi92HP8a-r16Cj425l-hnEdPV9cDXrnI130_provenance.
- NP125079.RArg2Yonr8hralR1HZiItX4Ts123Pxbp54ktfj9Ryt-As130_assertion description "[structural analysis of nucleophosmin mutations in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125079.RArg2Yonr8hralR1HZiItX4Ts123Pxbp54ktfj9Ryt-As130_provenance.
- NP125081.RAjhGi3CBtLK-gcPchPey2tOLYWx3-79UhXiKWeFOPUzk130_assertion description "[These results identify a unique miRNA signature associated with Acute myeloid leukemia (AML) carrying NPM1 mutations and cytoplasmic nucleophosmin (NPMc+ AML) and provide evidence that support a role for miRNAs in the regulation of HOX genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125081.RAjhGi3CBtLK-gcPchPey2tOLYWx3-79UhXiKWeFOPUzk130_provenance.
- NP125083.RAtE2_usaoWUDEY0EYNE2eT7PA-tjOMPAxi5ujx-BeBIs130_assertion description "[study confirms in 2562 patients with acute myeloid leukemia the previous observation that NPM1 mutations and cytoplasmic nucleophosmin are mutually exclusive of recurrent genetic abnormalities ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125083.RAtE2_usaoWUDEY0EYNE2eT7PA-tjOMPAxi5ujx-BeBIs130_provenance.
- NP125088.RAlb_U9YpIECShRfo0PE2eptqkXUHCYnHL4WUdYJt2gWE130_assertion description "[NPMc (+) acute myeloid leukemia represents a primary event rather than a transformation stage of NPMc (-) acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125088.RAlb_U9YpIECShRfo0PE2eptqkXUHCYnHL4WUdYJt2gWE130_provenance.
- NP125102.RAhKzyEyzcN66OjaKVdWJLK8U_fHdzyC1MqZO9mU3W14c130_assertion description "[The genotype distribution of the XPD gene does not indicate a role for base excision repair in the development of therapy-related acute myeloblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125102.RAhKzyEyzcN66OjaKVdWJLK8U_fHdzyC1MqZO9mU3W14c130_provenance.
- NP125105.RAnVsO5sVJdPIVlvSHhhAkg2nE3z1IcZ6IIrTjVpjKzbo130_assertion description "[study investigated which of the 2 gene products, AMLEVI1 or MDS1-EVI1, is involved in acute myeloid leukemia transformation and found that AMLEVI1 and not MDS1-EVI1 expression was associated with unfavorable karyotypes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125105.RAnVsO5sVJdPIVlvSHhhAkg2nE3z1IcZ6IIrTjVpjKzbo130_provenance.
- NP125107.RAkQxrC52VV9UowkXwVakUwyBX4yJGtKdhRqH-uiND9U0130_assertion description "[High EVI1 expression is associated with acute myeloid leukemias ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125107.RAkQxrC52VV9UowkXwVakUwyBX4yJGtKdhRqH-uiND9U0130_provenance.
- NP125113.RAjfGkjrwf72mjSYOUIiHfT-5rfCwUY8j9oRmSoQ29TBg130_assertion description "[hepatocyte growth factor has a role in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125113.RAjfGkjrwf72mjSYOUIiHfT-5rfCwUY8j9oRmSoQ29TBg130_provenance.
- NP125124.RAkkPIpaYpMUJ_FV7NC5OtXB6DUhZ6L9L6mnzzZBXusng130_assertion description "[Serum levels of angiogenin, basic fibroblast growth factor and endostatin in patients receiving intensive chemotherapy for acute myelogenous leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125124.RAkkPIpaYpMUJ_FV7NC5OtXB6DUhZ6L9L6mnzzZBXusng130_provenance.
- NP125128.RAhj6FRzUQPYoMn8icGArcAgvLprtLeNeWQ83MNCLwlJo130_assertion description "[Bcl-2 inhibition might therefore improve the efficacy of existing acute myeloid leukemia therapies by inactivating this suppression of wild-type p53 activity ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125128.RAhj6FRzUQPYoMn8icGArcAgvLprtLeNeWQ83MNCLwlJo130_provenance.
- NP125131.RAk0jjhkOtl7Ty0QFxg3RV5H-eOF6PQWNdW5qkLrMfG6Y130_assertion description "[In patients with acute myeloid leukemia there was no significant difference between serum leptin levels before and after chemotherapy or with a control group ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125131.RAk0jjhkOtl7Ty0QFxg3RV5H-eOF6PQWNdW5qkLrMfG6Y130_provenance.
- NP125135.RAjwWtw1JtUMzBR5IeeXewtDUjf9Fi0jqfRkqeN9kn7ZI130_assertion description "[circulating soluble selectin E in acute myeloid leukemia is correlated with peripheral blast cell counts, extramedullaary infiltration, relapse and mortality ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125135.RAjwWtw1JtUMzBR5IeeXewtDUjf9Fi0jqfRkqeN9kn7ZI130_provenance.
- NP125138.RAsxB7CMPqR9i_svTAntT2GlCFY9lXlriHcgwGuc0i11w130_assertion description "[Polymorphisms in ABCC3 is associated with acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125138.RAsxB7CMPqR9i_svTAntT2GlCFY9lXlriHcgwGuc0i11w130_provenance.
- NP125145.RAsC9Aal1Et02LAbDY_x25j7y3Hc2i-Dm97jQeKzmaTaQ130_assertion description "[MOZ complexes with TIF2 as a recombinant fusion protein which induces acute myelocytic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125145.RAsC9Aal1Et02LAbDY_x25j7y3Hc2i-Dm97jQeKzmaTaQ130_provenance.
- NP125146.RAr-UWMu4X6eK3ppF2ESSPTyU9fMOOoxWnGSUl5pLjVno130_assertion description "[analysis of MYST3-CBP fusion transcripts in t (8; 16) (p11; p13) acute myeloid leukemias ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125146.RAr-UWMu4X6eK3ppF2ESSPTyU9fMOOoxWnGSUl5pLjVno130_provenance.