Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP125149.RAovE5DibGsuax7y8uzJGl2LeidOGjb56vgnme2Q69gmQ130_assertion description "[Deletions have a negative prognostic value in adult acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125149.RAovE5DibGsuax7y8uzJGl2LeidOGjb56vgnme2Q69gmQ130_provenance.
- NP125152.RAr9CBCumxns8h9xfRJmxuWCym0XDWNCxPiG1kZPaUnSw130_assertion description "[The C-terminus of the G-CSF receptor, truncated in patients with severe congenital neutropenia/acute myeloid leukemia, is required for SH2-containing phosphatase-1 suppression of G-CSF-stimulated Stat activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125152.RAr9CBCumxns8h9xfRJmxuWCym0XDWNCxPiG1kZPaUnSw130_provenance.
- NP125155.RAuUNy2vHPYvdkqtcjXdZGGDNWO9P7Ps_LIqkVOUUd2KM130_assertion description "[TAF-Ialpha/CAN and TAF-Ibeta/CAN fusion transcripts are generated by chromosome 9q34 deletion in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125155.RAuUNy2vHPYvdkqtcjXdZGGDNWO9P7Ps_LIqkVOUUd2KM130_provenance.
- NP125162.RAhOZOLeaOKlFsUDSVnyoDcpHduAtDgtDe9qkUT8aamUM130_assertion description "[RUNX1-MTG16 fusion gene in acute myeloblastic leukemia with t (16/21) (q24'q22) is reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125162.RAhOZOLeaOKlFsUDSVnyoDcpHduAtDgtDe9qkUT8aamUM130_provenance.
- NP125164.RAnnqIn7q_eci_BmBpbA_zv9QO0BD_GhnuHZqVtk2Ujrs130_assertion description "[Perturbed modifications of histone H3 around the p15 CpG island region is associated with acute myeloblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125164.RAnnqIn7q_eci_BmBpbA_zv9QO0BD_GhnuHZqVtk2Ujrs130_provenance.
- NP125167.RAkBz2ACj2biI0BkCEhTN7PfgeYNiuDsoVnwlSFJCTIP8130_assertion description "[secretion from acute myelogenous leukemia blasts was up-regulated by leptin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125167.RAkBz2ACj2biI0BkCEhTN7PfgeYNiuDsoVnwlSFJCTIP8130_provenance.
- NP125173.RAtVx1ESI35uR1UshtErDa4g4P42sYVnAxtdSwmFr2new130_assertion description "[Malignant cells in high-risk myeloid dysplastic syndome and acute myeloid leukemia cells critically depend on IKKgamma/NEMO to survive.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125173.RAtVx1ESI35uR1UshtErDa4g4P42sYVnAxtdSwmFr2new130_provenance.
- NP125174.RAqmPKmhNU5ebS11zwGES8fOfvc8fFJVHKYnv0S0s-Jfg130_assertion description "[FIP1L1-PDGFRA-positive patients who presented with acute myeloid leukemia (AML, n = 5) or lymphoblastic T-cell non-Hodgkin-lymphoma (n = 2) in conjunction with AML or Eos-MPD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125174.RAqmPKmhNU5ebS11zwGES8fOfvc8fFJVHKYnv0S0s-Jfg130_provenance.
- NP125176.RAjFHmDUel8J59cdyDPIMTnOg3uLCZ1CUQEYuJtiaL2zs130_assertion description "[A high incidence of MMP-2 expression is confirmed in erythroblasts from acute myeloid leukemia (AML) patients and suggests the possible involvement of MMP-2 in the invasive phenotype of AML.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125176.RAjFHmDUel8J59cdyDPIMTnOg3uLCZ1CUQEYuJtiaL2zs130_provenance.
- NP125177.RAsKBzybqEg6PMIRV_mBQ-m_vRNxnnyqH91B-L_XCEXt8130_assertion description "[In the Acute Myeloid Leukemia patients, detected MLL rearrangements consisting of MLL/AF6, MLL/AF9, MLL/AF17, MLL/ELL and MLL partial tandem duplication/rearrangement include chromosome translocation and partial tandem duplication.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125177.RAsKBzybqEg6PMIRV_mBQ-m_vRNxnnyqH91B-L_XCEXt8130_provenance.
- NP125178.RAs3eg4Lo4Gmb6dhUzXpHpIBaetWRngwmxEGj6_jtnTJk130_assertion description "[In the Acute Myeloid Leukemia patients, detected MLL rearrangements consisting of MLL/AF6, MLL/AF9, MLL/AF17, MLL/ELL and MLL partial tandem duplication/rearrangement include chromosome translocation and partial tandem duplication.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125178.RAs3eg4Lo4Gmb6dhUzXpHpIBaetWRngwmxEGj6_jtnTJk130_provenance.
- NP125190.RAoZC8i6yqtpVN4OFxGuAdRNU-omPrHP-kYCxELrkeJ58130_assertion description "[A novel chromosomal inversion at 11q23 in acute myeloid leukemia fuses the MLL gene to the CALM gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125190.RAoZC8i6yqtpVN4OFxGuAdRNU-omPrHP-kYCxELrkeJ58130_provenance.
- NP125192.RAuDkfachCBwcH_PmXy3OYLnizC_NlzgavqN5wykeSwm0130_assertion description "[Involvement of the MLL gene located at chromosome region 11q23 is a frequent occurrence in both acute myelocytic leukemia and acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125192.RAuDkfachCBwcH_PmXy3OYLnizC_NlzgavqN5wykeSwm0130_provenance.
- NP125199.RAjy9mLOiibAcplCaqMVH2u5lfvRI1OyQaATvFeUVc-4g130_assertion description "[MGMT promoter methylation is not detectable in the investigated samples from acute myeloid leukemia patients/, MGMT mRNA expression is found to be normal in all but one case.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125199.RAjy9mLOiibAcplCaqMVH2u5lfvRI1OyQaATvFeUVc-4g130_provenance.
- NP125200.RAgVzir4iHIjmLYLgjfW-Ne_-gz9vqOoI0NvpiwB06cco130_assertion description "[analysis of the role of deregulated PcG genes in acute myeloid leukemia, and the downstream PcG targets HOXA4, HOXA9 and MEIS1 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125200.RAgVzir4iHIjmLYLgjfW-Ne_-gz9vqOoI0NvpiwB06cco130_provenance.
- NP125208.RAmrP6zjrtmOkj1VC2MbmQuPUUOWIZ0r-5Hm5uyBIMHvo130_assertion description "[A novel chromosomal inversion at 11q23 in acute myeloid leukemia fuses the CALM gene to the MLL gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125208.RAmrP6zjrtmOkj1VC2MbmQuPUUOWIZ0r-5Hm5uyBIMHvo130_provenance.
- NP125209.RAgaXR99M9LjPP4UuG-ZW6PCt2TXPQdsx-kHERBvwsrZY130_assertion description "[Primary acute myeloid leukemia cells express mesothelin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125209.RAgaXR99M9LjPP4UuG-ZW6PCt2TXPQdsx-kHERBvwsrZY130_provenance.
- NP125212.RAlbrZvjzDCHTcDsMXF19qsjqzgRJRVVq781HWveqDSbA130_assertion description "[higher WT1 expression was associated with favorable cytogenetics subtypes and accordingly with better outcome in children with acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125212.RAlbrZvjzDCHTcDsMXF19qsjqzgRJRVVq781HWveqDSbA130_provenance.
- NP125213.RAuZS57SpeVs9TWTDzgGyybntC9UT8Os275C7T86QdPfA130_assertion description "[The coexpression of the apoptosis-related genes bcl-2 and wt1 in predicting survival in adult acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125213.RAuZS57SpeVs9TWTDzgGyybntC9UT8Os275C7T86QdPfA130_provenance.
- NP125216.RAoyAWj4YUSnFQMyA2uAUUR0JE8Gf-VUSR3_W2wiLORFM130_assertion description "[Relapse was observed in eight of 17 patients with acute myelogenous leukemia analysed longitudinally, and an increase of WT1 gene expression preceded morphologic relapse in four patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125216.RAoyAWj4YUSnFQMyA2uAUUR0JE8Gf-VUSR3_W2wiLORFM130_provenance.
- NP125227.RAvQxmbOZoQOOSpm_9w468-e7EfZoTUkmFR4CJZKYM2IA130_assertion description "[PTPN11 missense mutations are associated with acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125227.RAvQxmbOZoQOOSpm_9w468-e7EfZoTUkmFR4CJZKYM2IA130_provenance.
- NP125233.RApxdYS39zOwCw1wLXp1maFPO4Gr1HzcGMr7tw5wmBNKI130_assertion description "[potential role of CDX2 in the development of human acute myeloid leukemia with aberrant Hox gene expression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125233.RApxdYS39zOwCw1wLXp1maFPO4Gr1HzcGMr7tw5wmBNKI130_provenance.
- NP125235.RAnZkRZW7eB_NhzbIMbfVPjAgohDDrA1cohe_7YFiqeAM130_assertion description "[Arf is haploinsufficient for the induction of acute myeloid leukemia in the presence of the inv (16) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125235.RAnZkRZW7eB_NhzbIMbfVPjAgohDDrA1cohe_7YFiqeAM130_provenance.
- NP125239.RAqt_l2Egl1KZlaSLguhx6bWrYhZdmdzc-BNAiOyAsPr4130_assertion description "[TIF2 complexes with MOZ as a recombinant fusion protein which induces acute myelocytic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125239.RAqt_l2Egl1KZlaSLguhx6bWrYhZdmdzc-BNAiOyAsPr4130_provenance.
- NP125241.RAoLy00FXTd9KpTHDyT5yD7gtkqefu2j2NzHyMr6_rRvo130_assertion description "[FIP1L1-PDGFRA-positive patients who presented with acute myeloid leukemia (AML, n = 5) or lymphoblastic T-cell non-Hodgkin-lymphoma (n = 2) in conjunction with AML or Eos-MPD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125241.RAoLy00FXTd9KpTHDyT5yD7gtkqefu2j2NzHyMr6_rRvo130_provenance.
- NP125244.RAhRlFhwZwmR2TsahCfYiWsMZf30WtHNYGMjQeRqTMMWo130_assertion description "[Analysis of blasts from single patients disclosed that LEDGF/p75 was the most consistently upregulated mRNA in resistant acute myelogenous leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125244.RAhRlFhwZwmR2TsahCfYiWsMZf30WtHNYGMjQeRqTMMWo130_provenance.
- NP125245.RAr2PfciOvWoquqAP2YTQk2Bsx_jcBzBJyWqK_aB_3pG4130_assertion description "[A novel fusion of the NUP98 and LEDGF genes in a pediatric case of acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125245.RAr2PfciOvWoquqAP2YTQk2Bsx_jcBzBJyWqK_aB_3pG4130_provenance.
- NP125246.RAogwmxzv8NQMURE_MctXGG0KUwXpxdxjTiMjWCS3zUcw130_assertion description "[BMI1 overexpression accompanied with 11q23 rearrangements is associated with acute myeloid leukemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125246.RAogwmxzv8NQMURE_MctXGG0KUwXpxdxjTiMjWCS3zUcw130_provenance.
- NP125250.RAlqGbhrs1asDFHDlePsmSY6KTcoUJDUf2Ce2ybklEwAs130_assertion description "[VEGF-A, STAT5 and AKT are downregulated in acute myeloid leukemia blasts of patients treated with SU5416 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125250.RAlqGbhrs1asDFHDlePsmSY6KTcoUJDUf2Ce2ybklEwAs130_provenance.
- NP125254.RAlWPC5k8shf93Sh8XUcA3VJVe8I7ie0vmY-kfIRBw7Fs130_assertion description "[NQO1 polymorphism confers interindividual variability of response to treatment in patients with acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125254.RAlWPC5k8shf93Sh8XUcA3VJVe8I7ie0vmY-kfIRBw7Fs130_provenance.
- NP125258.RAq6WXONDNqIu89SbTLC2P-8DAdXedPivHxCm6utmDIJk130_assertion description "[relationship between soluble resistance-related calcium-binding protein (sorcin) gene and multidrug resistance gene (mdr1), and their significance in clinical drug resistance and prognosis of acute myeloid leukemia (AML) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125258.RAq6WXONDNqIu89SbTLC2P-8DAdXedPivHxCm6utmDIJk130_provenance.
- NP125262.RAv-BdLkoXYpYm9wq8VkPwt0viuqktW67BUjUvX0DO8m8130_assertion description "[Serum beta2M levels can help predict outcome in patients greater than or = 60 years with untreated acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125262.RAv-BdLkoXYpYm9wq8VkPwt0viuqktW67BUjUvX0DO8m8130_provenance.
- NP125265.RAjmbmorGR0toXCNvBU7dZZoPBbXeSNcr4mfe2XJMtWXE130_assertion description "[WT1 may have a role in relapse of acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125265.RAjmbmorGR0toXCNvBU7dZZoPBbXeSNcr4mfe2XJMtWXE130_provenance.
- NP125284.RAi6PJjvrEJ_Oyx4Wd24HHjb4mqtZ6M2HGxH-xIZNWESM130_assertion description "[Serum levels of angiogenin, basic fibroblast growth factor and endostatin in patients receiving intensive chemotherapy for acute myelogenous leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125284.RAi6PJjvrEJ_Oyx4Wd24HHjb4mqtZ6M2HGxH-xIZNWESM130_provenance.
- NP125286.RAsr0Eoka0FXZlospCk3YP1da3V06xeyiRmwDIU_YoQ14130_assertion description "[Atiprimod blocked Stat3 activation and inhibited colony-forming cell proliferation in acute myeloid leukemia cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125286.RAsr0Eoka0FXZlospCk3YP1da3V06xeyiRmwDIU_YoQ14130_provenance.
- NP125288.RAn-Pwz3tVZPKWTwOhpBfqnNt468ygm_wv-PuED4U95as130_assertion description "[Bcl-xL prevents TRAIL-induced apoptosis by abrogating caspase activation and cleavage of BH3 interacting domain death agonist protein in acute myelogenous leukemia HL-60 cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125288.RAn-Pwz3tVZPKWTwOhpBfqnNt468ygm_wv-PuED4U95as130_provenance.
- NP125290.RAv-skQGewgIYO7PWmn61-hzzjuFgqeevueqEf1EUAic8130_assertion description "[Data demonstrate that the leukemia-propagating cell in murine CALM/AF10-positive acute myeloid leukemia differs from normal hematopoietic stem cells by B220 surface expression and immunoglobulin heavy chain rearrangement.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125290.RAv-skQGewgIYO7PWmn61-hzzjuFgqeevueqEf1EUAic8130_provenance.
- NP125297.RAs9-88OkVY29280ECKk0eHFFvejAdqKcepzQOs7wqynQ130_assertion description "[Results indicate the expression of functional B7-H2 molecule may facilitate progression of acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125297.RAs9-88OkVY29280ECKk0eHFFvejAdqKcepzQOs7wqynQ130_provenance.
- NP125301.RAi60UlXC6QBkpE3aapoEMY-Tgsr5UXX8S1_-yXmdTQCI130_assertion description "[The HOXA9 cluster gene is frequently expressed in cell lines from acute myeloid leukemia cases with 11p15 translocations; in some cases HOX9 is not fused to NUP98.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125301.RAi60UlXC6QBkpE3aapoEMY-Tgsr5UXX8S1_-yXmdTQCI130_provenance.
- NP125306.RAjOZV3hSlJbtgB4wog6pTjVzCqtUJBMLEvuZmoIGwjnk130_assertion description "[study shows that NUP98-NSD1 induces acute myeloid leukemia in vivo, sustains self-renewal of myeloid stem cells in vitro, and enforces expression of the HoxA7, HoxA9, HoxA10 and Meis1 proto-oncogenes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125306.RAjOZV3hSlJbtgB4wog6pTjVzCqtUJBMLEvuZmoIGwjnk130_provenance.
- NP125316.RAsA-LVeZrXSUopreaXjtMmJZ_KZufjOqA2XwN_c5AIRM130_assertion description "[close association of aberrant CD7 expression and FLT3/ITD mutation in the myeloblasts of FLT3/ITD+ acute myeloid leukemia suggests that FLT3/ITD- mediated leukemic transformation occurs in the more early stage of myeloid progenitor cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125316.RAsA-LVeZrXSUopreaXjtMmJZ_KZufjOqA2XwN_c5AIRM130_provenance.
- NP125317.RAlZ_M3r__rzT8Dt_wEGi4_Xsbd0xTl1rEK-Ot9ymIaeQ130_assertion description "[FLT3 mutation in acute myeloid leukemia confers a poorer prognosis in disease-free survival and overall survivalan even with a concomitant nucleophosmin1 (NMP1) mutation, which is normally a good prognostic factor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125317.RAlZ_M3r__rzT8Dt_wEGi4_Xsbd0xTl1rEK-Ot9ymIaeQ130_provenance.
- NP125322.RAjU4CBcIXkv19ku3UmiCrGzk9N4hp6R3XXcqUVSDqQak130_assertion description "[no correlation between size of duplicated sequences of FLT3 and disease outcome in acute myeloid leukemia patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125322.RAjU4CBcIXkv19ku3UmiCrGzk9N4hp6R3XXcqUVSDqQak130_provenance.
- NP125325.RAmdofYMb8n4zcKdCIIrJUaJjZ_lUEM4NGVXmeB2oXya8130_assertion description "[FLT3 signaling might play an important role in cell survival, especially at stem and progenitor cells that are critical cellular targets for acute myelogenous leukemia transformation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125325.RAmdofYMb8n4zcKdCIIrJUaJjZ_lUEM4NGVXmeB2oXya8130_provenance.
- NP125326.RAhObDmjLdBUEz7TBHlkHydaoRUJIOMYRAor41z1DMG_w130_assertion description "[FLT3 internal tandem repeat is associated with a high probability of evolution of myelodysplastic syndrome to acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125326.RAhObDmjLdBUEz7TBHlkHydaoRUJIOMYRAor41z1DMG_w130_provenance.
- NP125331.RAhrIeyYnt32ItcwE5a-kE9TzKZbrDYqXGkXs09Vf4uP4130_assertion description "[up-regulated by the AML1-MTG8 fusion protein, suggesting a role in the granulocytic maturation characteristic of the t (8; 21) acute myelogenous leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125331.RAhrIeyYnt32ItcwE5a-kE9TzKZbrDYqXGkXs09Vf4uP4130_provenance.
- NP125335.RAuTzMcNap34MtMShipBYlQPlTmFDZm0lNXLkplF3kBQU130_assertion description "[No significant correlation was found between FLT3 mutations and high levels of MDR1 in acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125335.RAuTzMcNap34MtMShipBYlQPlTmFDZm0lNXLkplF3kBQU130_provenance.
- NP125338.RAn_4VogOgLup2_mIXUoPVBlaRBXeYY3RIWnIqCoD1DV4130_assertion description "[Phosphorylation is inhibited by SU11248 in acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125338.RAn_4VogOgLup2_mIXUoPVBlaRBXeYY3RIWnIqCoD1DV4130_provenance.
- NP125342.RAjPAfSd_BHPZX3unnS4ySATPwKLCfRyxwZGrabJRzrC4130_assertion description "[analysis of MYST3-CBP fusion transcripts in t (8; 16) (p11; p13) acute myeloid leukemias ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125342.RAjPAfSd_BHPZX3unnS4ySATPwKLCfRyxwZGrabJRzrC4130_provenance.
- NP125343.RAsi_0gETngJhY_9W0ToU5uikj6fvIGdJ0wyr10cJBG3k130_assertion description "[Down-regulation of Notch-1 expression is associated with leukemogenesis in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125343.RAsi_0gETngJhY_9W0ToU5uikj6fvIGdJ0wyr10cJBG3k130_provenance.
- NP125345.RAn8M6qAoNk5sE5kVJap_wUSqB-0aCeDXWGcQ-bDZ6Rss130_assertion description "[expressed on CD3+/CD56+ large granular lymphocytes proliferating in response to a tumor-expressed activating ligand (CD48) and killing autologous leukemia cells by a novel mechanism in a patient with acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125345.RAn8M6qAoNk5sE5kVJap_wUSqB-0aCeDXWGcQ-bDZ6Rss130_provenance.
- NP125348.RAqvxvRR83PrJI-9S0wh-ssz93NJAcjUoy-uxyIqsYCyo130_assertion description "[CD34 antigen has 3 epitopes differeing in sensitivity to enzymatic cleavage/are expressed differently in different subtypes of acute myeloid leukemia and correlate with prognosis for disease-free survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125348.RAqvxvRR83PrJI-9S0wh-ssz93NJAcjUoy-uxyIqsYCyo130_provenance.
- NP125350.RArlrNd6L-9WMye3WlnEvbKwAnDIlyrjyCcW9CW1MC9iY130_assertion description "[NOR-1 is a critical tumor suppressor of myeloid leukemogenesis that is downregulated in leukemic blasts from acute myeloid leukemia patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125350.RArlrNd6L-9WMye3WlnEvbKwAnDIlyrjyCcW9CW1MC9iY130_provenance.
- NP125353.RAlPf0E7YQtPBj2SJA2EAzTLFX98v8aMj4-_uwV2Mby7Y130_assertion description "[the number and variety of ETV6 translocations together with loss of ETV6 by deletion makes a mutually supportive and compelling case for loss and haplo-insufficiency of ETV6 as a leukemogenic step in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125353.RAlPf0E7YQtPBj2SJA2EAzTLFX98v8aMj4-_uwV2Mby7Y130_provenance.
- NP125360.RAjhD29HBeH7TtUOz6MF4vLoF6imL0_uLX3mqefQ3O4os130_assertion description "[demonstrated that TET1 is fused to MLL in a case of pediatric acute myeloid leukemia containing the t (10; 11) (q22; q23) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125360.RAjhD29HBeH7TtUOz6MF4vLoF6imL0_uLX3mqefQ3O4os130_provenance.
- NP125367.RAnsdEDLFow1Otz2MqL9rnKshx_VFqTCsCZjOXFbfTyVw130_assertion description "[Constitutive phosphorylation of FKHR transcription factor is associated with acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125367.RAnsdEDLFow1Otz2MqL9rnKshx_VFqTCsCZjOXFbfTyVw130_provenance.
- NP125370.RAvLKWQBQZYt2pCKVpB-STUYqmfFG3RIwTuDoS-Xc1MXk130_assertion description "[Gene is associated with acute myeloid leukemia and with the risk of distant tissue infiltration by tumor cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125370.RAvLKWQBQZYt2pCKVpB-STUYqmfFG3RIwTuDoS-Xc1MXk130_provenance.
- NP125378.RAgLJ1MivUjKkNTgW7QoJXWyFOnJzI6MZT3dzNctn4DRY130_assertion description "[CD13 was expressed in 73% of acute myeloid leukemia patients, CD15 was expressed in 43% of patients, CD33 was expressed in 64% of patients, and CD34 was expressed in 66% of patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125378.RAgLJ1MivUjKkNTgW7QoJXWyFOnJzI6MZT3dzNctn4DRY130_provenance.
- NP125387.RAtFo6_nXmcEaqwyRuYmnH0aYr-nbvXBYA_1tJiNEn7Dg130_assertion description "[circulating soluble selectitn L in acute myeloid leukemia is correlaed with peripheral blast cell counts, extramedullaary infiltration, relapse and mortality ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125387.RAtFo6_nXmcEaqwyRuYmnH0aYr-nbvXBYA_1tJiNEn7Dg130_provenance.
- NP125392.RAmfVD9kvzAnhu8YG6kXzGt-utkJLzTb9PQfjJhITwFSs130_assertion description "[TAF-Ialpha/CAN and TAF-Ibeta/CAN fusion transcripts are generated by chromosome 9q34 deletion in acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125392.RAmfVD9kvzAnhu8YG6kXzGt-utkJLzTb9PQfjJhITwFSs130_provenance.
- NP125397.RAsg5n7gw4-AxCY2SrUrCCj7waGXGvOBy3r2Wqog75VEY130_assertion description "[The increased level of CCL17 and CCL22 release was important for acute myelogenous leukemia dendritic cell (AML-DC) chemotaxis of normal T cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125397.RAsg5n7gw4-AxCY2SrUrCCj7waGXGvOBy3r2Wqog75VEY130_provenance.
- NP125398.RAqIIs5wCwrPLHm70gZoPvbw5xRtckV-omqfioaAFPezE130_assertion description "[CD56 is expressed in bone marrow of acute myelogenous leukemias but not acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125398.RAqIIs5wCwrPLHm70gZoPvbw5xRtckV-omqfioaAFPezE130_provenance.
- NP125399.RAjezmApQ2sQXbzxDJQlyrAeVmrzb4hut6XP7kp3thSZU130_assertion description "[relative frequency of CD19 and/or CD56 expression in acute myeloid leukemia (AML) with t (8; 21) was significantly higher than those without this translocation and co-expression of these two antigens may serve as the surrogate markers for AML with t (8; 21) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125399.RAjezmApQ2sQXbzxDJQlyrAeVmrzb4hut6XP7kp3thSZU130_provenance.
- NP125401.RAprIPA-8EsmNLCvKvnrYw_PyJU3NHtaVTeVv54kN-2H8130_assertion description "[Per2 levels were reduced in lymphoma cell lines and in acute myeloid leukemia (AML) patient samples ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125401.RAprIPA-8EsmNLCvKvnrYw_PyJU3NHtaVTeVv54kN-2H8130_provenance.
- NP125407.RAte9_UXa2fc0fNdDqtEE_kIxxS7plkiIj5rD1SfQ2VQs130_assertion description "[Resistance to TRAIL-induced apoptosis in acute myeloid leukemia cells is associated with expression of TRAIL-R3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125407.RAte9_UXa2fc0fNdDqtEE_kIxxS7plkiIj5rD1SfQ2VQs130_provenance.
- NP125414.RAkfU4M0U2RXStNtAh16LsE0Bw3z6Gf8SOxeWwzjz_fxc130_assertion description "[Somatic point mutations in high-risk myelodysplastic syndrome, but not in myelofibrosis with myeloid metaplasia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125414.RAkfU4M0U2RXStNtAh16LsE0Bw3z6Gf8SOxeWwzjz_fxc130_provenance.
- NP125417.RAnaCimM_75RLPYN00hfke_GNGNS4h5XYEOkz8CkQRCic130_assertion description "[production by myelodysplastic syndrome blasts ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125417.RAnaCimM_75RLPYN00hfke_GNGNS4h5XYEOkz8CkQRCic130_provenance.
- NP125420.RAm-SHwUVWVnV4v0t79bGQN0CjYXgMjw8jpC1rgn6zMGE130_assertion description "[NPM1 mutations may be also involved in the pathogenesis of myelodysplastic syndromes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125420.RAm-SHwUVWVnV4v0t79bGQN0CjYXgMjw8jpC1rgn6zMGE130_provenance.
- NP125422.RAiQoERhlFrlG0_e-M-9AlczBz0IHUr2LCALxHaZF_2AA130_assertion description "[NPM1 expression levels of mRNA and protein in myelodysplastic syndromes were not related to chromosome 5 abnormalities and were almost the same as those in normal bone marrow and acute myeloid leukemia cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125422.RAiQoERhlFrlG0_e-M-9AlczBz0IHUr2LCALxHaZF_2AA130_provenance.
- NP125424.RAvKbG-It6CV0hVKpBoTcKHSCw3d4TUyCHWiqrk_mfnZ8130_assertion description "[RUNX1 mutation is associated with poor prognosis in patients with primary myelodysplastic syndrome/may play a role in the development and progression of a subset of primary myelodysplastic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125424.RAvKbG-It6CV0hVKpBoTcKHSCw3d4TUyCHWiqrk_mfnZ8130_provenance.
- NP125428.RAhLiD80KrA6pPkWBI0nkfNY_tfa0hWwBp94EZt30RxBU130_assertion description "[TGF-beta1 gene polymorphism may affect the disease progression in patients with myelodysplastic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125428.RAhLiD80KrA6pPkWBI0nkfNY_tfa0hWwBp94EZt30RxBU130_provenance.
- NP125429.RAkWvtxRgChDa3l53Ug9_RPi9aO6KznD8fukd8YYMJOTA130_assertion description "[Polymorphisms associated with increased expression in the cytokines TNFalpha and TGFbeta1 are overrepresented in the Myelodysplastic syndromes (MDS) population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125429.RAkWvtxRgChDa3l53Ug9_RPi9aO6KznD8fukd8YYMJOTA130_provenance.
- NP125436.RArEfBbyJeKkUjyX0AriT7m1__PHpih34Zn6KanPyot6c130_assertion description "[FLIP (L) and FLIP (S) are differentially regulated, and that the relative levels of both isoforms play a role in the regulation of apoptosis in myelodysplastic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125436.RArEfBbyJeKkUjyX0AriT7m1__PHpih34Zn6KanPyot6c130_provenance.
- NP125438.RAgfH_PeFr-hyCMwrLajd_wq5SDiv3Y35z5-dRD-u2Yc4130_assertion description "[Myelodysplastic syndrome patients with FHIT gene methylation had significantly shorter survival time than those without FHIT methylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125438.RAgfH_PeFr-hyCMwrLajd_wq5SDiv3Y35z5-dRD-u2Yc4130_provenance.
- NP125439.RAjCTEkgQ9tXWPKnrnQSjUl2kBVAT67j1ihc51z1902CU130_assertion description "[AML1-FOG2 and FOG2-AML1 are expressed in myelodysplastic syndrome; results suggest a central role for CtBP in AML1-FOG2 transcriptional repression and implicate coordinated disruption of AML1 and GATA developmental programs in the disease pathogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125439.RAjCTEkgQ9tXWPKnrnQSjUl2kBVAT67j1ihc51z1902CU130_provenance.
- NP125442.RAmwP1hR5OKYPK8rsvym1f_kYAKgRGlk411LywRNsQi-o130_assertion description "[Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125442.RAmwP1hR5OKYPK8rsvym1f_kYAKgRGlk411LywRNsQi-o130_provenance.
- NP125445.RAj6OpoTbZeqtxYmEkgzA1237rZx5JZ48XsBufCJ9j_R8130_assertion description "[Overexpression of KIS protein kinase is associated with acute myelogenous leukemia, myelodysplastic syndrome and acute lymphoblastic leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125445.RAj6OpoTbZeqtxYmEkgzA1237rZx5JZ48XsBufCJ9j_R8130_provenance.
- NP125454.RAp2kANvFTYrdepmSC9QHQfvwqy14loqpQZZZ2z1s_a2w130_assertion description "[the Cyclin D1/E2F1 pathway may be involved in apoptotic death of bone marrow cells in myelodysplastic syndromes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125454.RAp2kANvFTYrdepmSC9QHQfvwqy14loqpQZZZ2z1s_a2w130_provenance.
- NP125463.RAoVJ055Fjbq3iYw1U8atF46pgFVeaSwPTodAb_GnetMY130_assertion description "[downregulated in elderly persons and in myelodysplastic syndrome patients; reduction was more than 85% compared to younger adults ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125463.RAoVJ055Fjbq3iYw1U8atF46pgFVeaSwPTodAb_GnetMY130_provenance.
- NP125466.RAlKgfh5Szojeyj-t1dKBWYRvK9jNGLJoE-EzMD8Vyc4s130_assertion description "[four types of polymorphisms and 25 mutations were detected in CEBPA in samples from 390 patients with myelodysplastic syndrome (MDS) and hematologic malignancies ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125466.RAlKgfh5Szojeyj-t1dKBWYRvK9jNGLJoE-EzMD8Vyc4s130_provenance.
- NP125467.RAgsmtL1X3vYZT7hhLoXTX3JiXajGA7E4d-7A75TNItNg130_assertion description "[The CDKN2B was methylated in 50% (6/12) of the analyzed samples in pediatric myelodysplastic syndrome (MDS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125467.RAgsmtL1X3vYZT7hhLoXTX3JiXajGA7E4d-7A75TNItNg130_provenance.
- NP125469.RAmah8ZLwU72lQRKg8Kga3WCiVgWKMe4Y-IXGUGn7qztA130_assertion description "[The CALCA was methylated in 85.7% (18/21) of the analyzed samples in pediatric myelodysplastic syndrome (MDS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125469.RAmah8ZLwU72lQRKg8Kga3WCiVgWKMe4Y-IXGUGn7qztA130_provenance.
- NP125470.RAm11neo-h0yhjrJt4NLe4Q0FtIz0Dr5gedCsGLXSDWJE130_assertion description "[High expression of ERCC1, FLT1, NME4 and PCNA in myelodysplastic syndrome was associated with poor prognosis and disease progression along the sequence of 5q-syndrome/RCMD/RAEB/de novo AML ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125470.RAm11neo-h0yhjrJt4NLe4Q0FtIz0Dr5gedCsGLXSDWJE130_provenance.
- NP125472.RAjiJtYi2m0VM5YulQUCu9fU2yfMYtT3gOttnasTnSqqY130_assertion description "[A novel MLL-SEPT2 fusion variant in therapy-related myelodysplastic syndrome is reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125472.RAjiJtYi2m0VM5YulQUCu9fU2yfMYtT3gOttnasTnSqqY130_provenance.
- NP125474.RAvwy18HO4Ru8blJlJ_dGHpmHPbyRY1G1ojx2XKTXluPE130_assertion description "[The RAP1A gene mutation is a rare event in myelodysplastic syndromes (MDS) bone marrow cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125474.RAvwy18HO4Ru8blJlJ_dGHpmHPbyRY1G1ojx2XKTXluPE130_provenance.
- NP125475.RAi-MTB_NqsinQPMFN5gIg96fPm7q_ovZ-OHUqwtQqOyc130_assertion description "[AML1-FOG2 and FOG2-AML1 are expressed in myelodysplastic syndrome; results suggest a central role for CtBP in AML1-FOG2 transcriptional repression and implicate coordinated disruption of AML1 and GATA developmental programs in the disease pathogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125475.RAi-MTB_NqsinQPMFN5gIg96fPm7q_ovZ-OHUqwtQqOyc130_provenance.
- NP125480.RAttU1AgcoLQOsp1f1VOgv9cPdmJQ88jXfV2K3czcyBF8130_assertion description "[the Cyclin D1/E2F1 pathway may be involved in apoptotic death of bone marrow cells in myelodysplastic syndromes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125480.RAttU1AgcoLQOsp1f1VOgv9cPdmJQ88jXfV2K3czcyBF8130_provenance.
- NP125481.RAsp25W5OeZFkagyEND9xLDzJ0VKwy_2bhDtDoatv1MLY130_assertion description "[dysregulation of IGFBP-3 in patients with myelodysplastic syndromes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125481.RAsp25W5OeZFkagyEND9xLDzJ0VKwy_2bhDtDoatv1MLY130_provenance.
- NP125482.RAhxyXnVd6eMfSqLatvWYSCfJioUr8vFrylp8exLXOExc130_assertion description "[GATA-1 and GATA-2 gene expression is related to the severity of dysplasia in myelodysplastic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125482.RAhxyXnVd6eMfSqLatvWYSCfJioUr8vFrylp8exLXOExc130_provenance.
- NP125486.RAs1-uFYCKm07Lqn6ZM2zcWXu87teh8OLMr5mkGPwnfRw130_assertion description "[Apoptotic index (includes nick-end labeling) and bcl-2 do not correlate with key clinical data (prognosis and blood counts at diagnosis) in patients with myelodysplastic syndrome, whie p53 protein levels do.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125486.RAs1-uFYCKm07Lqn6ZM2zcWXu87teh8OLMr5mkGPwnfRw130_provenance.
- NP125492.RAtyCss1yBKMn3Lh2jgWXGHHuW_fBj4wCHgLGkwjqpEaU130_assertion description "[Acquisition of FLT3 mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125492.RAtyCss1yBKMn3Lh2jgWXGHHuW_fBj4wCHgLGkwjqpEaU130_provenance.
- NP125500.RAuhpjk8Q61kDCrNQ8wHIzDqQYtGnSDUZEUHjTNuoCnj8130_assertion description "[myelodysplastic syndrome CD34 (+) -derived erythroid progenitors underwent abnormal Fas-dependent apoptosis during differentiation that could be responsible for the impaired erythropoiesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125500.RAuhpjk8Q61kDCrNQ8wHIzDqQYtGnSDUZEUHjTNuoCnj8130_provenance.
- NP125502.RAsHjJAfZmpLof3DWZoSlsn1TC4MyaOqiLGtTuFvteM5Y130_assertion description "[The expression of Dlk1 was found to be up-regulated in CD34+ cells from patients with myelodysplastic syndrome (MDS) by analyzing the gene expression profiles determined by microarray.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125502.RAsHjJAfZmpLof3DWZoSlsn1TC4MyaOqiLGtTuFvteM5Y130_provenance.
- NP125503.RAqCmeI0rKMarZCCYeHsR5Jj73WkG-uxX1wOD9CPQue0U130_assertion description "[The mRNA expression level of the gene delta-like (Dlk) was measured using real-time PCR methodology in a large series of control biopsies and bone marrow trephines from patients with myelodysplastic syndrome and related myeloid disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125503.RAqCmeI0rKMarZCCYeHsR5Jj73WkG-uxX1wOD9CPQue0U130_provenance.
- NP125504.RAjLpHtUx55r2BWvjPQGHWHJl_bXfbCQZZLAtMOV4bIrQ130_assertion description "[The product of the ETV6-MDS2 fusion transcript in a patient with myelodysplastic syndrome predicts a short ETV6 protein containing the first 54 amino acids of ETV6 plus four novel amino acids, lacking both the PTN and the DNA-binding domains.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125504.RAjLpHtUx55r2BWvjPQGHWHJl_bXfbCQZZLAtMOV4bIrQ130_provenance.
- NP125505.RAgES6o_hs8kLz-8wbwPT95jG8awXmBpmBGmw-Ui33Jb0130_assertion description "[These results suggest that Flt3 inhibitors might exert an anti-neoplastic effect in high-risk myelodysplastic syndrome and acute myeloid leukemia through inhibition of NFkappaB.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125505.RAgES6o_hs8kLz-8wbwPT95jG8awXmBpmBGmw-Ui33Jb0130_provenance.
- NP125506.RAkBq4bYcBdydc1TOS9TGcqoxuQ5UFbiL7a3M8GT4OB8o130_assertion description "[Genetic abnormality in the KIT gene, particularly at codon 816, might contribute to the progression of myelodysplastic syndromes to acute myelocytic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125506.RAkBq4bYcBdydc1TOS9TGcqoxuQ5UFbiL7a3M8GT4OB8o130_provenance.
- NP125507.RAjYODTqmM51xNIweMNGDtwMdC5TJW8FrArMowgePfMv0130_assertion description "[Blood levels are elevated in myelodysplastic syndromes and in acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125507.RAjYODTqmM51xNIweMNGDtwMdC5TJW8FrArMowgePfMv0130_provenance.
- NP125511.RAjfJIw9Me8QKpNQtVpi0rxFJ6TnLVlNc5I_BqHzGMaVY130_assertion description "[production by myelodysplastic syndrome blasts ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125511.RAjfJIw9Me8QKpNQtVpi0rxFJ6TnLVlNc5I_BqHzGMaVY130_provenance.
- NP125516.RAnEi87Gly99QsG3xnkAYcHQOojrVWNvdgMOfr1n_cL10130_assertion description "[Decreased phosphorylation of protein kinase B and erk1/erk2 in neutrophils from patients with myelodysplastic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP125516.RAnEi87Gly99QsG3xnkAYcHQOojrVWNvdgMOfr1n_cL10130_provenance.