Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP145400.RAtoQVzwRUnAcdqSmREKpYjx5aukVTA8SwjyipQoUP0bw130_assertion description "[Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145400.RAtoQVzwRUnAcdqSmREKpYjx5aukVTA8SwjyipQoUP0bw130_provenance.
- NP145404.RAs2WDZPiTvRnAA4KFxCh1n4BF_PalEoBZiUSnxdJ3-k0130_assertion description "[The majority of Langerhans cell histiocytosis cells express this protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145404.RAs2WDZPiTvRnAA4KFxCh1n4BF_PalEoBZiUSnxdJ3-k0130_provenance.
- NP145405.RAshBDMFjHs0uR40RxFQlOt7qnkN3u0mcnka5Pg0paG9E130_assertion description "[The majority of Langerhans cell histiocytosis cells express FADD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145405.RAshBDMFjHs0uR40RxFQlOt7qnkN3u0mcnka5Pg0paG9E130_provenance.
- NP145407.RAk7Rle_3_N7NR2qPG2Yrh5nvuANDHwYotkGnqR-nQyVA130_assertion description "[Increased serum level of interleukin-1 receptor antagonist is associated with children with Langerhans cell histiocytosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145407.RAk7Rle_3_N7NR2qPG2Yrh5nvuANDHwYotkGnqR-nQyVA130_provenance.
- NP145408.RAshxbcw_eFm45WpwVHWdzdSOgjPBDPX6KmukawhFgWyw130_assertion description "[The majority of Langerhans cell histiocytosis cells express FADD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145408.RAshxbcw_eFm45WpwVHWdzdSOgjPBDPX6KmukawhFgWyw130_provenance.
- NP145420.RAqsi2JeK-3B8SLpDPhDbnrPIo2Zieq2kAoaU6sd1sMMI130_assertion description "[identified a POMT2 homozygous missense mutation in a girl with a mild limb-girdle muscular dystrophy (LGMD) phenotype ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145420.RAqsi2JeK-3B8SLpDPhDbnrPIo2Zieq2kAoaU6sd1sMMI130_provenance.
- NP145426.RAjwhNF-meXhz0ZXEBRGq3eHFhiBaZSN4_MosMrOM7XJA130_assertion description "[Clinical, histologic, and immunohistochemical characteristics of three children with limb-girdle muscular dystrophy type 2C/novel mutations in the gamma-sarcoglycan gene were present/found phenotypic differences in two brothers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145426.RAjwhNF-meXhz0ZXEBRGq3eHFhiBaZSN4_MosMrOM7XJA130_provenance.
- NP145427.RAlMPx1cQPTysO6VPUdc5xvg9GgnME2_r9ltKPskNS_qs130_assertion description "[( c-FLIP), which is dependent on the NF-kappaB pathway in normal muscle cells, is down-regulated in limb-girdle muscular dystrophy type 2A biopsies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145427.RAlMPx1cQPTysO6VPUdc5xvg9GgnME2_r9ltKPskNS_qs130_provenance.
- NP145436.RAqKL2ZfgQvC_DT6U54TpDykHhirm6ml5-w51302iGvO4130_assertion description "[Study provides evidence of the pathogenetic effect of specific CAPN3 gene mutations on protein function in limb girdle muscular dystrophy type 2A muscle and offers insights into the protein regions that are crucial for the autolytic activity of calpain-3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145436.RAqKL2ZfgQvC_DT6U54TpDykHhirm6ml5-w51302iGvO4130_provenance.
- NP145441.RAtayhrdVzD3a8sV0djQxxA44AMVgTDhGigSWRtVoM88Y130_assertion description "[findings detected a homozygous mutation of the FKRP gene (826C > A) in two unrelated patients with limb-girdle muscular dystrophy 2I with necrotic myopathy with numerous rimmed vacuoles ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145441.RAtayhrdVzD3a8sV0djQxxA44AMVgTDhGigSWRtVoM88Y130_provenance.
- NP145447.RAvA154SIVbUSVwuftBxXJ_UY9Eqm1BUq0ganFjaYiXTI130_assertion description "[LMNA mutation is associated with autosomal dominant Emery-Dreifuss mucular dystrophy amd limb-girdle muscular dystrophy ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145447.RAvA154SIVbUSVwuftBxXJ_UY9Eqm1BUq0ganFjaYiXTI130_provenance.
- NP145450.RAgkRQ-1F9vqUjR-TA-QR00AKCXQLc0h7P9DOtpXe3y6w130_assertion description "[Review/mutations can result in four distinct, sometimes overlapping, muscle disease phenotypes: limb girdle muscular dystrophy, rippling muscle disease, distal myopathy, and hyperCKemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145450.RAgkRQ-1F9vqUjR-TA-QR00AKCXQLc0h7P9DOtpXe3y6w130_provenance.
- NP145452.RAlwpFgTWvuE-4v5413S6yyVmqCmaDqEY68cdcSlOEmfQ130_assertion description "[AQP4 expression was analyzed in muscle biopsies from patients affected by Limb Girdle Muscular Dystrophies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145452.RAlwpFgTWvuE-4v5413S6yyVmqCmaDqEY68cdcSlOEmfQ130_provenance.
- NP145464.RAuE5iuKE_XLIjsbf7fcCLTUFIcPnxt1kRbIljbJPckS8130_assertion description "[These data demonstrate specific activation of c-FLIP by HCMV IE2 and indicate a novel role for c-FLIP in the pathogenesis of HCMV retinitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145464.RAuE5iuKE_XLIjsbf7fcCLTUFIcPnxt1kRbIljbJPckS8130_provenance.
- NP145465.RAp0vDpNzTcFUNPU5bFM03yZaT9P4N6Lp_wytNRmaQKU4130_assertion description "[These results suggest that the PKC gamma R659S mutation is susceptible to neuronal death and is involved in the pathogenesis of neurodegenerative diseases, including Retinitis pigmentosa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145465.RAp0vDpNzTcFUNPU5bFM03yZaT9P4N6Lp_wytNRmaQKU4130_provenance.
- NP145468.RAgpibC4iIPwRhjkLOQaClgF4-JRHxsjXsBX0cgUYm8NY130_assertion description "[Inward potassium current in bladder urothelial cells (BUC) can be modulated by EGF and HB-EGF/in BUC membrane potassium conductance caused by altered levels of EGF and HB-EGF may therefore play role in pathophysiology of interstitial cystitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145468.RAgpibC4iIPwRhjkLOQaClgF4-JRHxsjXsBX0cgUYm8NY130_provenance.
- NP145469.RAlu_ufHouwUSWOyEoB8RtycVMC3QbvQAzUbKH6q12-xI130_assertion description "[Inward potassium current in bladder urothelial cells (BUC) can be modulated by EGF and HB-EGF/in BUC membrane potassium conductance caused by altered levels of EGF and HB-EGF may therefore play role in pathophysiology of interstitial cystitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145469.RAlu_ufHouwUSWOyEoB8RtycVMC3QbvQAzUbKH6q12-xI130_provenance.
- NP145476.RAvDmD_ciut3Ady5Ei0k1-Tz7J46KfF_QyU3bsf4rSUrQ130_assertion description "[CREB is a critical regulator of human GRP-R expression in gastrointestinal cancer and might be activated through different upstream intracellular pathways.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145476.RAvDmD_ciut3Ady5Ei0k1-Tz7J46KfF_QyU3bsf4rSUrQ130_provenance.
- NP145480.RAowU9Iyl7DlrYcYKEXj0TB2HhR-VoW3R88XKLTzLf23Y130_assertion description "[There is a significant loss of ELF-1 and reduced Smad4 expression in gastrointestinal neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145480.RAowU9Iyl7DlrYcYKEXj0TB2HhR-VoW3R88XKLTzLf23Y130_provenance.
- NP145483.RAnECuPMJdp3MhVzwJq6DO-DsK_Z5FBMFwjDgHFG8hXic130_assertion description "[qRT-PCR assay targeted to plakophilin 3 and anterior gradient-2 mRNAs might be helpful to detect circulating tumor cells in patients with gastrointestinal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145483.RAnECuPMJdp3MhVzwJq6DO-DsK_Z5FBMFwjDgHFG8hXic130_provenance.
- NP145485.RAt1HmIJOzxTBuLZbT2_NtqyVUcQ3YPmjx6HpVIj4X9P0130_assertion description "[qRT-PCR assay targeted to plakophilin 3 and anterior gradient-2 mRNAs might be helpful to detect circulating tumor cells in patients with gastrointestinal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145485.RAt1HmIJOzxTBuLZbT2_NtqyVUcQ3YPmjx6HpVIj4X9P0130_provenance.
- NP145487.RAv-wC7kAWztqebPKt3x19Ec42eZbVyzWf-Rrr6u1h0P4130_assertion description "[The expressions of SNC19/matriptase and its inhibitor HAI-1 are decreased in gastrointestinal cancer tissues ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145487.RAv-wC7kAWztqebPKt3x19Ec42eZbVyzWf-Rrr6u1h0P4130_provenance.
- NP145490.RAk94K-Vr1Hzmo8a9sc1akmX6MMn-movsDdcFqtWRd9L8130_assertion description "[It is possible to apply a simple and reliable method for the detection of circulating tumor cells based on cytokeratin-20 and prostate stem cell antigen RT-PCR assays in gastrointestinal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145490.RAk94K-Vr1Hzmo8a9sc1akmX6MMn-movsDdcFqtWRd9L8130_provenance.
- NP145492.RArxipNAUDdk3DUfZHRpkH48GlDDAzPTe-qtTrzhrvcWs130_assertion description "[This is the first report of FADD gene mutation in gastrointestinal cancers, and data suggest that the FADD gene is rarely mutated in human colon and stomach cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145492.RArxipNAUDdk3DUfZHRpkH48GlDDAzPTe-qtTrzhrvcWs130_provenance.
- NP145495.RAqCzpG4iGu459Fard1gfQyyopQVzUbSxm4Tg_Pt8jqV8130_assertion description "[M146L mutant PS-1 may predispose to both Pick's disease and AD by affecting multiple intracellular pathways involving tau phosphorylation and amyloid metabolism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145495.RAqCzpG4iGu459Fard1gfQyyopQVzUbSxm4Tg_Pt8jqV8130_provenance.
- NP145502.RAuUFAvskVNPWlJlHMUkB1AD8hCNYs6jwmf7Oh-CdePbM130_assertion description "[The significant increase in peroxiredoxin 6 level in frontal cortex of patients with Pick's disease is useful in discriminating it from Down syndrome/Alzheimer's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145502.RAuUFAvskVNPWlJlHMUkB1AD8hCNYs6jwmf7Oh-CdePbM130_provenance.
- NP145506.RAkUfy9fUzWBM312Q3JxCHQl239AjE2mEkimcI4vctR6w130_assertion description "[This study proposes a novel mechanism of TIMP-1 regulation, which ensures an increased supply of the inhibitor after brain injury, and limits extracellular matrix degradation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145506.RAkUfy9fUzWBM312Q3JxCHQl239AjE2mEkimcI4vctR6w130_provenance.
- NP145508.RAjAtxCK0BywVtGchswl1VZjfaVbpmBhOAMyS8GJBsVXE130_assertion description "[Traumatic brain injury was not associated with higher rates of amnestic mild cognitive impairment or dementia, and APOE-epsilon4 was not associated with cognition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145508.RAjAtxCK0BywVtGchswl1VZjfaVbpmBhOAMyS8GJBsVXE130_provenance.
- NP145509.RAouO2JRUVVfK2TFDA439gDAWK9N-37kwtVktb3dZcA00130_assertion description "[Patients with ApoE epsilon4 genotype were more likely to have severe clinical symptomatology and unfavorable neurological outcome after traumatic brain injury compared to significantly better outcome with other ApoE genotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145509.RAouO2JRUVVfK2TFDA439gDAWK9N-37kwtVktb3dZcA00130_provenance.
- NP145514.RAo8snOV99k5HiX0mreds-9aVInqR6m85DTNGqCwMeCS0130_assertion description "[article reviews the current understanding of the genetic susceptibility of traumatic brain injury (TBI) and the advancements regarding the impact of apolipoprotein E genotype on the severity and/or outcome following TBI [review]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145514.RAo8snOV99k5HiX0mreds-9aVInqR6m85DTNGqCwMeCS0130_provenance.
- NP145521.RAmkIsZDhp1XcqE1I5Q5B4cHnqA_0XOYumnBtswNLlBzc130_assertion description "[In conclusion, our results provide correlative evidence for the " PPARgamma-- > UCP2-- > neuroprotection " cascade in ischemic brain injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145521.RAmkIsZDhp1XcqE1I5Q5B4cHnqA_0XOYumnBtswNLlBzc130_provenance.
- NP145524.RAkiOO1egLhQoH3gicohfZmfzSBBPNucraC0Qp81H1bus130_assertion description "[BNP is elevated within 24 h after traumatic brain injury in some patients; it does not originate from the brain and increased NT-proBNP concentrations are not consistently associated with hyponatremia or increased urinary sodium loss ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145524.RAkiOO1egLhQoH3gicohfZmfzSBBPNucraC0Qp81H1bus130_provenance.
- NP145532.RAlCi56NSPzVqfaThMzAxxiOusBwQkgtU4wBlyAmjFYE4130_assertion description "[Results provide evidence that protein degradation of alphaII-spectrin is a reliable marker of severe traumatic brain injury (TBI) in humans and that both necrotic and apoptotic cell death mechanisms are activated in humans following a severe TBI.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145532.RAlCi56NSPzVqfaThMzAxxiOusBwQkgtU4wBlyAmjFYE4130_provenance.
- NP145537.RAuZYktSDT6Aw1chIIpUhkhj9nd_jVIWLtqVxoFM1lhv0130_assertion description "[In traumatic brain injury, the ability of patients to mount a response to receptor antagonist interleukin (IL) -1ra, as measured in cerebrospinal fluid, strongly correlates with the neurological outcome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145537.RAuZYktSDT6Aw1chIIpUhkhj9nd_jVIWLtqVxoFM1lhv0130_provenance.
- NP145539.RAhkBO2BSV9NDCtt0v_ne2W1mM90buQwn7LqwsR81YlaQ130_assertion description "[An increase of endostatin/collagen XVIII-positive macrophages/microglial cells is observed, but not astrocytes, up to day 14 and a consequent decrease to day 16 in patients with post-traumatic brain injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145539.RAhkBO2BSV9NDCtt0v_ne2W1mM90buQwn7LqwsR81YlaQ130_provenance.
- NP145540.RAjpVFXUALBLJx3lZNNC0bAeYDkVhF1s0CUspANHIwYJc130_assertion description "[Data suggest that increased intrathecal release of Fas, but not FasL or caspase 3, in the cerebrospinal fluid of infants with hydrocephalus may serve as an indicator of brain injury from progressive ventricular dilatation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145540.RAjpVFXUALBLJx3lZNNC0bAeYDkVhF1s0CUspANHIwYJc130_provenance.
- NP145545.RAl50AtPP2xWMUx1vNRivRRVP9YDYe22vAm7UviPDr6W8130_assertion description "[Increased PGRN expression by microglia may play a pivotal role in the response to brain injury, neuroinflammation and neurodegeneration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145545.RAl50AtPP2xWMUx1vNRivRRVP9YDYe22vAm7UviPDr6W8130_provenance.
- NP145553.RArJYI0pzg9EsIArs6YMNLsMWW9ZRNeSdVXBrGJVXNH_8130_assertion description "[NSE increases to similar degrees with and without traumatic brain injury ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145553.RArJYI0pzg9EsIArs6YMNLsMWW9ZRNeSdVXBrGJVXNH_8130_provenance.
- NP145558.RAlAlnh4o-e1Qk4TR1DSAyewaZ_2H3Bssh5emS2ZBrLEA130_assertion description "[The present results provide confirmatory evidence for an allelic and genotypic association of the CX36 gene with juvenile myoclonic epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145558.RAlAlnh4o-e1Qk4TR1DSAyewaZ_2H3Bssh5emS2ZBrLEA130_provenance.
- NP145560.RAqa0XGCKFmOB-HpQC-lQFKKbpMgLuVH0K6N-Wll-I5gc130_assertion description "[Nine percent of consecutive juvenile myoclonic epilepsy cases from Mexico and Honduras clinics and 3% of clinic patients from Japan carry mutations in Myoclonin1/EFCH1 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145560.RAqa0XGCKFmOB-HpQC-lQFKKbpMgLuVH0K6N-Wll-I5gc130_provenance.
- NP145562.RAquzKoe-nlcQlqy0Azj8peGSW04QhwuFd0QlP4I1uYlc130_assertion description "[In this case of juvenile myoclonic epilepsy, A molecular genetic analysis led to the identification of a polymorphism (A-- > G) in position 10 in the intron 3 (rs949626) of the EFHC1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145562.RAquzKoe-nlcQlqy0Azj8peGSW04QhwuFd0QlP4I1uYlc130_provenance.
- NP145569.RAvVt-dBo7n0MlxjQBo3UspFuXsyUJdY--mCAXWmqJJMo130_assertion description "[Data show that the apolipoprotein E epsilon3/epsilon4 genotype is more frequently seen in the simple febrile than in the complicated febrile convulsion group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145569.RAvVt-dBo7n0MlxjQBo3UspFuXsyUJdY--mCAXWmqJJMo130_provenance.
- NP145573.RAlnTxBgj40I4cma4o3TZp2ychvSC02_uXCEnBeNC4Lho130_assertion description "[Identification of an Nav1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145573.RAlnTxBgj40I4cma4o3TZp2ychvSC02_uXCEnBeNC4Lho130_provenance.
- NP145577.RAgrBxTi8c94DJdA8YjuW1Ks01x7tvGsNOj8MdhufbCIE130_assertion description "[findings illustrate that SCN1A mutations can cause simple febrile seizures associated with temporal lobe epilepsy, which differ from the characteristic clinical spectrum of generalized epilepsy with febrile seizures plus ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145577.RAgrBxTi8c94DJdA8YjuW1Ks01x7tvGsNOj8MdhufbCIE130_provenance.
- NP145590.RAuZ5MxsEDgxfKyyXxJiIp5uW4DjHBIuOyKSyosaoBkRA130_assertion description "[imbalance of serum matrix metallopeptidase 9 and tissue inhibitors of metalloproteinases 1 levels in patients with acute encephalopathy following prolonged febrile seizures may be associated with severe neurological sequelae ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145590.RAuZ5MxsEDgxfKyyXxJiIp5uW4DjHBIuOyKSyosaoBkRA130_provenance.
- NP145591.RAoTFU2ttUnbg2up24sjzzOfxHNvafH6QMuLSgV5Cs35Y130_assertion description "[Levels of IL-6 in severe cases of influenza-associated encephalopathy are significantly higher than those levels in mild cases, compared with IL-6 levels in patients with febrile convulsion and rotavirus-associated convulsion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145591.RAoTFU2ttUnbg2up24sjzzOfxHNvafH6QMuLSgV5Cs35Y130_provenance.
- NP145597.RAijSGjy0NSUAMZwWaq8MLpsTLG-VT0R9S47w2_E6xgJs130_assertion description "[Non-melanoma skin cancers express functional purinergic receptors and that P2X7 receptor agonists significantly reduce cell numbers in vitro.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145597.RAijSGjy0NSUAMZwWaq8MLpsTLG-VT0R9S47w2_E6xgJs130_provenance.
- NP145604.RApLEi_i5Vm5bJmf2UMOCpvXbi0QIgUDe0Qn8v_gGUBME130_assertion description "[effects of the MC1R variants on skin cancer risk were independent from self-reported phenotypic pigmentation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145604.RApLEi_i5Vm5bJmf2UMOCpvXbi0QIgUDe0Qn8v_gGUBME130_provenance.
- NP145607.RAsnIf9WLNTgywDFZsZe29CWTFwhHOQjgSIfreow1FvJY130_assertion description "[The effect of discovered MC1R variants on the individual's pigmentation characteristics, or risk of skin cancer, remains to be elucidated ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145607.RAsnIf9WLNTgywDFZsZe29CWTFwhHOQjgSIfreow1FvJY130_provenance.
- NP145613.RAlQvhow4TXD7lud-9SOJ-Z9XaP6Ws104tABwiq1aacME130_assertion description "[Downregulation of MMP-19 expression in the epidermis is associated with transformation and histologic dedifferentiation in skin neoplasms ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145613.RAlQvhow4TXD7lud-9SOJ-Z9XaP6Ws104tABwiq1aacME130_provenance.
- NP145617.RAso2nM_nu771Fz36KQgnTuUfS6hVThHgTZXVKMt2jCkw130_assertion description "[Non-melanoma skin cancers express functional purinergic receptors and that P2X7 receptor agonists significantly reduce cell numbers in vitro.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145617.RAso2nM_nu771Fz36KQgnTuUfS6hVThHgTZXVKMt2jCkw130_provenance.
- NP145618.RAo7oe2fnfn5YmhYChuVDXiJ1ncs5nzhnPpVDQUFVa560130_assertion description "[SOX9 expression is a general feature of basal cell carcinomas and adnexal skin neoplasms, suggesting a contribution of SOX9 to the pathogenesis of these tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145618.RAo7oe2fnfn5YmhYChuVDXiJ1ncs5nzhnPpVDQUFVa560130_provenance.
- NP145623.RAh_GeC7rBVW3IGWWAjmiQB56Yfvk0GelF7-LZ0O3UeIc130_assertion description "[EphA1 seems to be a marker of the differentiated normal epidermis and its downregulation in nonmelanoma skin cancer may contribute to carcinogenesis of these very frequent human tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145623.RAh_GeC7rBVW3IGWWAjmiQB56Yfvk0GelF7-LZ0O3UeIc130_provenance.
- NP145625.RAjxWCHs4nTimj9GRd4KuBzE99l0zwwN70r--y32cOKJ8130_assertion description "[Patients with nonmelanoma skin cancer who have the variant XPD Gln allele are increased risk of developing second primary cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145625.RAjxWCHs4nTimj9GRd4KuBzE99l0zwwN70r--y32cOKJ8130_provenance.
- NP145626.RAtSq2xAgWK0vFK9V6sFHsx_nckrK6Qp8Nkfy8ZX7NZU0130_assertion description "[CB2 plays a role in inhibiting neovascularization and skin neoplasm development ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145626.RAtSq2xAgWK0vFK9V6sFHsx_nckrK6Qp8Nkfy8ZX7NZU0130_provenance.
- NP145628.RAi3-51t-yvbGp7StqTNUYMEgmPSlUvN7_T_4-sqYP4Wc130_assertion description "[MMP-2, MMP-9, TIMP-1 and TIMP-2 play an important role in the pathogenesis of non-melanoma skin cancer/immunoexpression of these proteins may be useful indicators of cutaneous cancer invasion and progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145628.RAi3-51t-yvbGp7StqTNUYMEgmPSlUvN7_T_4-sqYP4Wc130_provenance.
- NP145631.RAjFlGUi5kIOoA8Sa-lCr0iEVOnn8xRzaiNOKKcTytUj4130_assertion description "[p53 has a role in skin pigmentation as well as in skin neoplasms ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145631.RAjFlGUi5kIOoA8Sa-lCr0iEVOnn8xRzaiNOKKcTytUj4130_provenance.
- NP145637.RAoJIxqCBsd0zFgtVfh8pZH4CFTp0qpaMA5lh3Sy8-N5I130_assertion description "[Microsatellite instability and modifications in the hMLH1 and hMSH2 genes are implicated in a significant proportion of the patients with head and neck cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145637.RAoJIxqCBsd0zFgtVfh8pZH4CFTp0qpaMA5lh3Sy8-N5I130_provenance.
- NP145638.RApP6B3t8J6apGUA22hCUW8N32ij1Jmr_Ok7xttsXMEE8130_assertion description "[Overexpressed eIF4E is associated with head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145638.RApP6B3t8J6apGUA22hCUW8N32ij1Jmr_Ok7xttsXMEE8130_provenance.
- NP145640.RAvswetFWxvxMOWvUWp3s3S2roIxrpyYe5eEDwTnoRbzU130_assertion description "[Cx30 expression in head and neck cancer was drastically reduced compared to apparently normal mucosa while Cx26 expression was almost the same.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145640.RAvswetFWxvxMOWvUWp3s3S2roIxrpyYe5eEDwTnoRbzU130_provenance.
- NP145645.RAvAdmq0NwjmmC1afysBS1m50d1yUBeWebWyI22ionZ50130_assertion description "[Finds that MTR variant AG and AG/GG genotypes associated with a significantly increased squamous cell head and neck cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145645.RAvAdmq0NwjmmC1afysBS1m50d1yUBeWebWyI22ionZ50130_provenance.
- NP145647.RAhConTbHPM0mB20Lc5KjhKSiIgpmYnLFAEcKfP3Wdfl8130_assertion description "[SolCD44 is elevated in the majority of head and neck cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145647.RAhConTbHPM0mB20Lc5KjhKSiIgpmYnLFAEcKfP3Wdfl8130_provenance.
- NP145649.RAuXQYVuP2p6N7-5i8_dSIq6wnNSOETx9sNuhbSTY7Uo0130_assertion description "[polymorphism in codon 72 and risk of head and neck neoplasms ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145649.RAuXQYVuP2p6N7-5i8_dSIq6wnNSOETx9sNuhbSTY7Uo0130_provenance.
- NP145652.RAi0gRL4M3lWorW10OJq9YjkkxXquL2uwAiLsjJr42JPk130_assertion description "[Genetic variation increases had and neck cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145652.RAi0gRL4M3lWorW10OJq9YjkkxXquL2uwAiLsjJr42JPk130_provenance.
- NP145656.RAhEVraL2np17IwhApmkSc1Fiy8d0edLjlzr2bh13Tl9k130_assertion description "[The FGFR4 Gly388Arg polymorphism had consistent associations with survival outcomes in head and neck neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145656.RAhEVraL2np17IwhApmkSc1Fiy8d0edLjlzr2bh13Tl9k130_provenance.
- NP145657.RAv-w_c3mHPFriFLtn2qchXZ3HOhVhQqk2zdrj1RcjC-I130_assertion description "[The presence of CD4+CD25+ (regulatory T cells in head and neck cancer patients might be, in part, responsible for downregulation of antitumour immune responses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145657.RAv-w_c3mHPFriFLtn2qchXZ3HOhVhQqk2zdrj1RcjC-I130_provenance.
- NP145663.RAuyRLzMtU6nZBhpzUZtac8ETE8XEkNu-NjvZhmOfoFkU130_assertion description "[Overexpression of DSG3 is associated with head and neck cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145663.RAuyRLzMtU6nZBhpzUZtac8ETE8XEkNu-NjvZhmOfoFkU130_provenance.
- NP145664.RArZmvMgBpkBG6_xcaRNaHHWFiQLFY03RRa1vdlOE3ApU130_assertion description "[Increased activity of this enzyme enhances the malignant phenotype of human head and neck cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145664.RArZmvMgBpkBG6_xcaRNaHHWFiQLFY03RRa1vdlOE3ApU130_provenance.
- NP145665.RAhkY3LcN7eFzgxVfdm57ZNRYuc_FdSzMyJ5XVMNZwn-E130_assertion description "[These results suggest a possible role for BRCA1 in modulating cisplatin sensitivity in head and neck cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145665.RAhkY3LcN7eFzgxVfdm57ZNRYuc_FdSzMyJ5XVMNZwn-E130_provenance.
- NP145666.RAicNvwu_aahrPepxbRCMEbVILpzDFeKByJH8LPoFIvHk130_assertion description "[Up-regulation of natural killer cell function against head and neck cancer in response to single-stranded immunostimulatory RNA requires TLR7.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145666.RAicNvwu_aahrPepxbRCMEbVILpzDFeKByJH8LPoFIvHk130_provenance.
- NP145672.RAufb53npJiU8zq7Y9xzUAflth-8b5q5KN4jAsJnehXuA130_assertion description "[Potentially interesting value of the serum levels of sEGFR and EGF, especially when combined, as markers for non-small cell lung cancer and head and neck cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145672.RAufb53npJiU8zq7Y9xzUAflth-8b5q5KN4jAsJnehXuA130_provenance.
- NP145677.RApzuh4kAQbNEGrQHglRVbRSoLbnXGZg7vXVVVcPQxt84130_assertion description "[Mutation in XRCC3 gene may be associated with increased risk of squamous cell carcinoma of head and neck neoplasms ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145677.RApzuh4kAQbNEGrQHglRVbRSoLbnXGZg7vXVVVcPQxt84130_provenance.
- NP145680.RAs4IPrBF1BHwOdXWNwoRXz3oDZsaXfgDqm0299BxwLGo130_assertion description "[Review of COX-2 expression in squamous cell head and neck neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145680.RAs4IPrBF1BHwOdXWNwoRXz3oDZsaXfgDqm0299BxwLGo130_provenance.
- NP145682.RApNyEO8UEa6PjgfELFJzpPEtO1YDpmiwysWcCamJwbH0130_assertion description "[COX-2 overexpression in glottic cancer was associated with increased overall mortality and an increased risk of second primary cancers in head and neck cancer patients during the early follow-up period ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145682.RApNyEO8UEa6PjgfELFJzpPEtO1YDpmiwysWcCamJwbH0130_provenance.
- NP145684.RArUlgKniGqMhZpdLVp_B__1AQaQQHD3JMh_fpTZFVxOU130_assertion description "[we show for the first time that cyclooxygenase-1 is overexpressed in head and neck cancer cells compared to epithelial cells of normal mucosa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145684.RArUlgKniGqMhZpdLVp_B__1AQaQQHD3JMh_fpTZFVxOU130_provenance.
- NP145687.RAtPrV0VyGVSAC12ATcobwZsCpodTRcbCxcdj4ePR8LaE130_assertion description "[findings corroborate metabolic genes interactions, especially for CYP1A1 462Val alleles and GSTM1 homozygous deletion, in the development of head and neck cancer in the investigated population groups in Poland ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145687.RAtPrV0VyGVSAC12ATcobwZsCpodTRcbCxcdj4ePR8LaE130_provenance.
- NP145695.RAsYx5r_Rw_Cv6OZHo8qBpDqBPkN0vKqLuMlf_gHsFvBQ130_assertion description "[Short [CAG]n repeat length (</= 20) polymorphism is associated with poor prognosis in a subset of male patients with head and neck cancer and that AR gene microsatellite instability is uncommon in these tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145695.RAsYx5r_Rw_Cv6OZHo8qBpDqBPkN0vKqLuMlf_gHsFvBQ130_provenance.
- NP145696.RAmF-hN-OhfRmhb9vBsZwdcQrpxDeuLm8ArRBab3SvoCI130_assertion description "[study showed there were no significant differences in the frequencies of CCR5 genotypes and alleles between head and neck cancer patients and controls ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145696.RAmF-hN-OhfRmhb9vBsZwdcQrpxDeuLm8ArRBab3SvoCI130_provenance.
- NP145700.RApCttfgVXxaHNgBlp5NkIR9myWDarboBvbJypNpwYNIc130_assertion description "[High HIF-2alpha expression is associated with head and neck cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145700.RApCttfgVXxaHNgBlp5NkIR9myWDarboBvbJypNpwYNIc130_provenance.
- NP145706.RAtgDQyx1RwHZlglijbbWnenSk74df44B7Ru5RHT7Gvcc130_assertion description "[PUMA suppresses tumor cell growth in head/neck cancer, but it does not appear to be a direct target of inactivation in head and neck tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145706.RAtgDQyx1RwHZlglijbbWnenSk74df44B7Ru5RHT7Gvcc130_provenance.
- NP145708.RAhe2xUjrBV9Rnl4mDR_BFzjB_Q_AWtJPpYKMB__hwDVw130_assertion description "[iNOS protein seems to be associated with extracapsular spread and invasion in head and neck cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145708.RAhe2xUjrBV9Rnl4mDR_BFzjB_Q_AWtJPpYKMB__hwDVw130_provenance.
- NP145711.RApAWverW37lydWtOOboZffHumxX5Q9LGf0g5NJbCs8PM130_assertion description "[Inactivating SFRP1 methylation occurred in all Barrett esophagus samples and in 96% of esophageal adenocarcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145711.RApAWverW37lydWtOOboZffHumxX5Q9LGf0g5NJbCs8PM130_provenance.
- NP145712.RAjCnO1pxJDp-kJkwjFq_TyfDcbKvSem_uC-SfVHWGg5Q130_assertion description "[The high frequency of promoter hypermethylation and progressive loss of GPx3 expression in Barrett's adenocarcinomas suggest that epigenetic inactivation may be critical in the development and progression of Barrett's esophagus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145712.RAjCnO1pxJDp-kJkwjFq_TyfDcbKvSem_uC-SfVHWGg5Q130_provenance.
- NP145714.RAtJB9i2JUqclplPZRnspckUuz9JE4StAeMU4F4mjwB5U130_assertion description "[Hypermethylation of p16, RUNX3, and HPP1 in Barreett exophagus may represent independent risk factors for the progression of Barrett esophagus to esophageal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145714.RAtJB9i2JUqclplPZRnspckUuz9JE4StAeMU4F4mjwB5U130_provenance.
- NP145722.RAvE3Jn22zMeragh_4_Aup67MWFpQNLQKvjJi3BopvzHo130_assertion description "[SNPs involving the GSTP1, MnSOD and GPX2 genes were not associated with Barrett's esophagus or esophageal adenocarcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145722.RAvE3Jn22zMeragh_4_Aup67MWFpQNLQKvjJi3BopvzHo130_provenance.
- NP145724.RAsNO4QJtfaAO11ngVL7elRlrJpOSbWr-EnQSEog4CZUQ130_assertion description "[Cdx2 is a highly sensitive marker for Barrett's esophagus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145724.RAsNO4QJtfaAO11ngVL7elRlrJpOSbWr-EnQSEog4CZUQ130_provenance.
- NP145726.RAh6c815fHDYhjbBHQnd1QjluCB4tuL4TtlN8AfgCNctQ130_assertion description "[Hypermethylation of p16, RUNX3, and HPP1 in Barreett exophagus may represent independent risk factors for the progression of Barrett esophagus to esophageal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145726.RAh6c815fHDYhjbBHQnd1QjluCB4tuL4TtlN8AfgCNctQ130_provenance.
- NP145735.RAu3qRqrpMyI92lIEq30-92Igy6TJEP17EYROZtycK2M8130_assertion description "[The ability of Cdx1 and c-myc to initiate the earliest stages of transdifferentiation of esophageal keratinocytes toward a cell fate characteristic of Barrett's esophagus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145735.RAu3qRqrpMyI92lIEq30-92Igy6TJEP17EYROZtycK2M8130_provenance.
- NP145738.RAhBNVi2rr2L18hG8qgmqWts3gFGmpSz3JHGu9bkFDVDM130_assertion description "[No apparent selection trend was established with neoplastic progression or aneuploidy for BUB1 in Barrett esophagus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145738.RAhBNVi2rr2L18hG8qgmqWts3gFGmpSz3JHGu9bkFDVDM130_provenance.
- NP145741.RAm7Jtsqm2Njr4O1BrUpyXhpvn3udV1NO19aVqUDSt5fE130_assertion description "[Reduced expression of EpCAM and villin is associated withn Barrett's adenocarcinoma and expression of EpCam and villin differs only between squamous epithelium and Barrett esophagus ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145741.RAm7Jtsqm2Njr4O1BrUpyXhpvn3udV1NO19aVqUDSt5fE130_provenance.
- NP145742.RAuS7DW58MD-hfhZ1u207VHsrwPR9KmYi5KG11Hc5QKcY130_assertion description "[expression pattern is unique to Barrett's esophagus ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145742.RAuS7DW58MD-hfhZ1u207VHsrwPR9KmYi5KG11Hc5QKcY130_provenance.
- NP145744.RAvMYUdIXs8DypM3tH11AMLKxoahWV3Qj1JDXrQcdE4Xc130_assertion description "[REG expression in Barrett's esophagus/of REG Ialpha was more frequently observed in patients who showed squamous re-epithelialization of Barrett's esophagus at biopsy sites.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145744.RAvMYUdIXs8DypM3tH11AMLKxoahWV3Qj1JDXrQcdE4Xc130_provenance.
- NP145745.RAjmETrmpGBcHiuYxp9nvNah--Qk9HlQ6r_9Ji2pDB2vo130_assertion description "[No apparent selection trend was established with neoplastic progression or aneuploidy for MAD2 in Barrett esophagus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145745.RAjmETrmpGBcHiuYxp9nvNah--Qk9HlQ6r_9Ji2pDB2vo130_provenance.
- NP145747.RAs3RyRreyJ1rlvq8w6AAy9zUGLs_leU5gYktvDVWe5Sw130_assertion description "[COX-2 and EGFR may be cooperative in the stepwise progression from Barrett's esophagus to adenocarcinoma, thereby leading to carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145747.RAs3RyRreyJ1rlvq8w6AAy9zUGLs_leU5gYktvDVWe5Sw130_provenance.
- NP145752.RAjafTHia3mYGa-vQmBC-Ojs2e8DywSXGmeezFIIVOqpo130_assertion description "[Upregulation of MUC2 reflects intestinal metaplasia in Barrett's esophagus ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145752.RAjafTHia3mYGa-vQmBC-Ojs2e8DywSXGmeezFIIVOqpo130_provenance.
- NP145756.RAnfVAUNzEJA6TaSoF-TaPpdEr8t4REidgLVefimEUiwE130_assertion description "[GSTP1 B allele carriers were more frequent among the patients with Barrett's esophagus (BE) when compared to controls; GSTP1 gene might be one of the risk factors associated with susceptibility to reflux esophagitis, especially to BE ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145756.RAnfVAUNzEJA6TaSoF-TaPpdEr8t4REidgLVefimEUiwE130_provenance.
- NP145767.RAmur9saxhTs2Z07rXExbTJs_uGne7FF6prJvkl_2PAcQ130_assertion description "[Our observations of frequent deletion of TSC2 and the mTOR signalling pathway provide evidence that the oncogenetic lineage of PEComa, as a distinct TSC2-linked neoplasm, is similar to that of angiomyolipoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145767.RAmur9saxhTs2Z07rXExbTJs_uGne7FF6prJvkl_2PAcQ130_provenance.
- NP145769.RApRXBCUJw5k3Hk3G-kWTIjJoTl-mVo6w_hq4SeTlHkxk130_assertion description "[Ser (326) Cys variant of OGG1 may confer risk for development of angiomyolipomas by increasing oxidative DNA damage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145769.RApRXBCUJw5k3Hk3G-kWTIjJoTl-mVo6w_hq4SeTlHkxk130_provenance.
- NP145771.RAuVFt8ZlmhNR1AsBo0rVqWcGIttpCJP71IAkRNgV7WTk130_assertion description "[HMB-45 (melanoma-associated antigen p97) and Melan-A combined were positive in 100% of the renal angiomyolipomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145771.RAuVFt8ZlmhNR1AsBo0rVqWcGIttpCJP71IAkRNgV7WTk130_provenance.
- NP145774.RAlIhVwlYCTEMVb-sQqSg79fboyLpq8QOhPq8a-AXw6QA130_assertion description "[Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP145774.RAlIhVwlYCTEMVb-sQqSg79fboyLpq8QOhPq8a-AXw6QA130_provenance.