Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence The+Spanish+Flu+virus+resembles+avian+influenza+A+viruses+in+its+ability+to+recruit+Crk%2FCrkL+to+modulate+host+cell+signaling. assertion.
- assertion asSentence CrkI+and+p130%28Cas%29+complex+regulates+the+migration+and+invasion+of+prostate+cancer+cells. assertion.
- assertion asSentence Cbl-b+plays+a+negative+role+in+Crk-L-C3G-mediated+Rap1+and+LFA-1+activation+in+T+cells. assertion.
- assertion asSentence CRKL+permits+cells+to+bypass+the+strict+need+for+adhesion+in+response+to+FGF8+through+direct+interaction+with+receptor. assertion.
- assertion asSentence CTGF+inhibits+metastasis+and+invasion+of+human+lung+adenocarcinoma+by+a+CRMP-1-dependent+mechanism. assertion.
- assertion asSentence Loss+of+CRMP1+contribute+to+the+increased+invasive+phenotype+of+human+Glioblastoma+multiforme+brain+tumors+expressing+mutant+EGFRvIII. assertion.
- assertion asSentence C-reactive+protein+directly+stimulates+monocyte+adhesion+to+vascular+endothelial+cells. assertion.
- assertion asSentence Circulating+CRP+concentrations+can+be+markedly+suppressed%2C+independently+of+total+adiposity+or+indeed+fat+mass%2C+by+intense+regular+physical+exercise. assertion.
- assertion asSentence CRP+modifies+the+relation+between+blood+pressure+and+microalbuminuria. assertion.
- assertion asSentence Human+recombinant+CRP+directly+inhibits+endothelial+progenitor+cell+differentiation%2C+survival%2C+%26+function%2C+key+components+of+angiogenesis+and+the+response+to+chronic+ischemia%2Cpartlyvia+an+effect+of+CRP+to+reduce+EPC+eNOS+expression. assertion.
- assertion asSentence In+young+subjects+with+uncomplicated+type+1+diabetes%2C+even+slightly+elevated+high+ssensitivity+CRP+concentrations+are+associated+with+reduced+coronary+vasoreactivity. assertion.
- assertion asSentence C-reactive+protein+elevation+predicts+the+occurrence+of+atrial+structural+remodeling+in+patients+with+paroxysmal+atrial+fibrillation. assertion.
- assertion asSentence Magnesium+intake+is+inversely+associated+with+plasma+C-reactive+protein+%28CRP%29+levels. assertion.
- assertion asSentence Elevations+in+pCRP+level+in+medically+healthy+personality+disordered+subjects+with+higher+scores+of+trait+aggression+and+hostility. assertion.
- assertion asSentence Elevated+levels+of+CRP+are+associated+with+the+presence+and+extent+of+angiographically+verified+Coronary+Artery+Disease. assertion.
- assertion asSentence Genetic+variation+in+the+CRP+gene+is+associated+with+plasma+CRP+levels+and+cardiovascular+disease+risk+in+older+adults. assertion.
- assertion asSentence CRP+enhances+myeloma+cell+proliferation+under+stressed+conditions+and+protects+myeloma+cells+from+chemotherapy+drug-induced+apoptosis+in+vitro. assertion.
- assertion asSentence The+impact+of+the+IL6+-634G+allele+on+serum+C-reactive+protein+elevation+is+greater+in+nonsmokers+than+in+current+smokers. assertion.
- assertion asSentence hsCRP+levels+should+be+adjusted+for+BMI%2C+ethnicity%2C+education+level%2C+disease+activity+and+medications+when+conducting+cardiovascular+risk+assessment+in+patients+with+lupus. assertion.
- assertion asSentence CRP+and+pro-inflammatory+cytokines+%28IL-6+and+IL-8%29+are+strong+predictors+of+all-cause+and+cardiovascular+mortality. assertion.
- assertion asSentence In+post-myocardial+patients%2C+heritability+of+lung+function+is+at+least+partly+controlled+by+the+C+reactive+protein+gene. assertion.
- assertion asSentence The+diagnostic+performance+of+hsCRP+in+distinguishing+3-vessel+coronary+artery+disease+from+less+extensive+forms+of+coronary+atherosclerosis+is+more+accurate+in+a+group+of+subjects+without+the+apoE+epsilon4+allele+than+in+patients+with+it. assertion.
- assertion asSentence High-sensitivity+C-reactive+protein+is+not+independently+associated+with+peripheral+subclinical+atherosclerosis. assertion.
- assertion asSentence The+effect+of+CRP+genetics+on+early+atherosclerotic+changes+is+modulated+by+the+FCGR2A+genetics. assertion.
- assertion asSentence CRP+measurement+is+independently+associated+with+short-term+mortality+risk+in+type+2+diabetic+individuals. assertion.
- assertion asSentence In+patients+with+a+history+of+paroxysmal+or+persistent+atrial+fibrillation+treated+with+catheter+ablation%2C+elevated+levels+of+IL-6+and+hs-CRP+before+ablation+are+independent+predictors+of+recurrence. assertion.
- assertion asSentence Raised+serum+C-reactive+protein+concentration+at+the+time+of+presentation+of+advanced+pancreatic+cancer+carries+a+poor+prognosis+independent+of+biliary+tract+obstruction. assertion.
- assertion asSentence Left+atrial+appendage+velocity+and+C-reactive+protein+are+independently+associated+with+the+risk+of+thromboembolism+in+patients+with+atrial+fibrillation+undergoing+transesophageal+echocardiography. assertion.
- assertion asSentence C-reactive+protein+decreased+following+resistance+exercise+training+in+young+African-American+men. assertion.
- assertion asSentence Circulating+levels+of+autoantibodies+to+oxidized+low-density+lipoprotein+and+C-reactive+protein+levels+correlate+with+endothelial+function+in+resistance+arteries+in+men+with+coronary+heart+disease. assertion.
- assertion asSentence A+high+CRP+level+predisposes+to+increased+cardiovascular+risk+in+MetS. assertion.
- assertion asSentence Despite+variability+over+time%2C+inflammation+assessed+by+using+CRP+level+is+a+strong+predictor+of+mortality. assertion.
- assertion asSentence In+the+oldest-old%2C+high+CRP+levels+are+associated+with+increased+odds+of+all-cause+dementia%2C+particularly+in+women. assertion.
- assertion asSentence Measurement+of+C-reactive+protein+levels+added+to+those+of+cardiac+troponin+I+and+B-type+natriuretic+peptide+improves+the+risk+assessment+of+long-term+adverse+cardiac+outcome+after+cardiac+surgery. assertion.
- assertion asSentence The+acceleration+of+arterial+wall+stiffness+in+CKD+is+associated+with+additional+factors%2C+i.e.+fetuin+A+deficiency+and+higher+CRP+and+IL-6. assertion.
- assertion asSentence Elevated+levels+of+cystatin+C+are+independently+associated+with+inducible+ischemia+among+outpatients+with+stable+coronary+disease. assertion.
- assertion asSentence Elevated+C-reactive+protein+levels+are+associated+with+micro%2Fmacroalbuminuria+independent+of+diabetes%2C+hypertension. assertion.
- assertion asSentence THP-1+cells+differentiated+into+macrophage-like+cells+by+treatment+with+phorbol+12-myristate+13-acetate+internalized+fluorescently+labeled+CRP. assertion.
- assertion asSentence Elevated+levels+of+C-reactive+protein+and+fibrinogen+and+reduced+level+of+adiponectin+can+be+used+for+early+diagnosis+of+type+2+diabetes+mellitus+and+can+predict+diabetic+complications. assertion.
- assertion asSentence High-sensitivity+C-reactive+protein+is+a+reliable+biological+marker+for+the+inflammatory+component+of+metabolic+syndrome+in+Japanese. assertion.
- assertion asSentence Diagnostic+value+of+interleukin-6+and+C-reactive+protein+on+early+onset+bacterial+infection+in+preterm+neonates+with+respiratory+distress. assertion.
- assertion asSentence Increased+human+CRP+expression+exacerbates+left+ventricular+dysfunction+and+adverse+LV+remodeling+after+myocardial+infarction+without+affecting+infarct+size+in+mice. assertion.
- assertion asSentence Boys+who+carry+the+GG+genotype+of+CRP+%2B2147+A%2FG+and+the+CC+genotype+of+IL-6R+rs2229238+C%2FT+have+a+greater+risk+of+having+abnormal+body+size+and+of+developing+obesity+than+individuals+who+do+not+have+these+genotypes. assertion.
- assertion asSentence Human+CRP+plays+an+active+role+in+inducing+hepatic+insulin+resistance+in+the+rat%2C+at+least+in+part+by+activating+ERK1%2F2%2C+with+downstream+impairment+in+the+insulin+signaling+pathway. assertion.
- assertion asSentence Higher+CRP+levels+in+pregnancy+are+associated+with+wheezing+and+lower+respiratory+tract+infections+in+offspring. assertion.
- assertion asSentence The+level+of+NT-proBNP+in+conjunction+with+hs-CRP+can+predict+the+prognosis+of+heart+failure+patients. assertion.
- assertion asSentence Elevated+plasma+hCRP+levels+promote+thrombus+formation+on+injured+smooth+muscle+cell-rich+neointima+by+enhancing+TF+expression. assertion.
- assertion asSentence A+persistent+increase+of+plasma+fibrinogen%2FC-reactive+protein+is+associated+with+an+increased+risk+of+early+atherosclerosis. assertion.
- assertion asSentence Serum+CRP+and+hematoma+volume+are+predictors+of+short-term+mortality+in+spontaneous+intracerebral+hemorrhage. assertion.
- assertion asSentence Severity+of+low-grade+inflammation+in+cardiovascular+disease+is+related+to+increases+in+plasma+CRP+and+B-type+natriuretic+peptide+%28BNP%29. assertion.
- assertion asSentence C-reactive+protein+gene+polymorphism+is+associated+with+colorectal+cancer. assertion.
- assertion asSentence High+serum+C-reactive+protein+and+IL-6+is+associated+with+lymph+node+metastasis+in+breast+cancer. assertion.
- assertion asSentence Under+physiological+conditions%2C+phosphoethanolamine+is+bound+with+higher+affinity+by+human+SAP+than+by+human+CRP. assertion.
- assertion asSentence Plasma+CRP+concentrations+associate+with+cognitive+performance+in+part+through+pathways+independent+of+%28risk+factors+for%29+cardiovascular+disease. assertion.
- assertion asSentence CRX+expression+in+the+inner+nuclear+layer+of+the+retina. assertion.
- assertion asSentence Human+cryptochrome-1+confers+light+independent+biological+activity+in+transgenic+Drosophila+correlated+with+flavin+radical+stability. assertion.
- assertion asSentence Elevated+alpha+crystallin+is+associated+with+highly+infiltrative+apoptosis-resistant+glioblastoma. assertion.
- assertion asSentence Methylglyoxal+modification+destroys+the+folded+structure+and+hydrophobic+clefts+in+a-crystallin+accelerating+cataract+formation+of+eye+lens. assertion.
- assertion asSentence Subunits+of+alphaB+crystallin+that+exchange+dynamically+with+the+alphaB+crystallin+complex+can+interact+with+tubulin+subunits+to+regulate+the+equilibrium+between+tubulin+and+microtubules. assertion.
- assertion asSentence The+importance+of+defining+a+role+for+VEGF+signaling+in+sustaining+aberrant+tumor+angiogenesis+and+strongly+implicate+UPR%2FCRYAB+as+dichotomous+parts+of+a+crucial+regulation+pathway+for+maintaining+intracrine+VEGF+signaling. assertion.
- assertion asSentence CRYAB+functions+to+suppress+nasopharyngeal+carcinoma+progression+by+associating+with+the+cadherin%2Fcatenin+adherens+junction+and+modulating+the+beta-catenin+function. assertion.
- assertion asSentence Comprehensive+description+of+the+biophysical+consequences+of+a+mutant+beta-crystallin+protein+that+is+associated+with+human+inherited+cataract. assertion.
- assertion asSentence Delta91+mutation+arise+in+a+relatively+mutation-prone+sequence+of+the+CRYBA1+gene. assertion.
- assertion asSentence The+c.279-281delGAG+mutation+in+CRYBA1+is+responsible+for+the+autosomal+dominant+congenital+nuclear+cataract+disease+in+this+Chinese+family. assertion.
- assertion asSentence Mutation+G220X+is+associated+with+autosomal+dominant+cataract. assertion.
- assertion asSentence The+Asp+residue+at+position+4+of+betaB2-crystallin+in+the+lenses+of+the+aged+human+eye+lenses+undergoes+a+significant+degree+of+inversion+and+isomerization+to+the+biologically+D-beta-Asp. assertion.
- assertion asSentence Human+gammaD-crystallin+formed+amyloid+fibrils+upon+incubation+at+acid+pH. assertion.
- assertion asSentence Deamidation+in+cataractous+lenses+is+influenced+by+surface+exposure. assertion.
- assertion asSentence Its+ketimine+reductase+activity+is+strongly+inhibited+by+thyroid+hormones. assertion.
- assertion asSentence Distinct+roles+for+phosphoinositide+3-kinase%2C+mitogen-activated+protein+kinase+and+p38+MAPK+in+mediating+cell+cycle+progression+of+breast+cancer+cells. assertion.
- assertion asSentence Both+Ca%282%2B%29-dependent+and+p38+kinase-mediated+phosphorylation+events%2C+causes+reassembly+of+the+actin+cytoskeleton+and+subsequent+appearance+of+membrane+blebs+at+the+plasma+membrane. assertion.
- assertion asSentence Dual+effect+of+UVB%2C+to+stimulate+maturation+or+to+induce+apoptosis+in+monocyte+derived+dendritic+cells%2C+depending+on+the+dosage%2C+via+p38+MAPK+pathway. assertion.
- assertion asSentence p38+is+a+central+component+of+NK+cell+ability+to+directly+respond+to+dsRNA+pathogen-associated+molecular+pattern+%28PAMP%29. assertion.
- assertion asSentence A+specific+requirement+for+p150%28Glued%29%2Fdynein%2Ffunctional+microtubules+in+activation+of+MKK3%2F6+and+p38+MAPKs+in+vivo. assertion.
- assertion asSentence IL-1beta-induced+cPLA2+and+COX-2+gene+expression+is+modulated+through+the+p38+MAPK+pathway+in+both+neuroglioma+and+neuroblastoma+cells. assertion.
- assertion asSentence p160+coactivator+glucocorticoid+receptor-interacting+protein+1+%28GRIP1%29+is+phosphorylated+and+potentiated+by+the+p38+MAPK+signaling+cascade+in+vitro+and+in+vivo. assertion.
- assertion asSentence p38+plays+a+key+role+during+small+intestinal+ischemia+reperfusion+injury+through+a+proapoptotic+action+on+the+tip+of+villi. assertion.
- assertion asSentence DUSP26+effectively+dephosphorylates+p38+and+has+a+little+effect+on+extracellular+signal-regulated+kinase+in+anaplastic+thyroid+cancer. assertion.
- assertion asSentence p38+alpha+MAP+kinase+is+one+of+the+critical+downstream+signals+for+development+of+cardiomyopathy+following+chronic+beta+2-adrenergic+receptor+stimulation+in+transgenic+mice. assertion.
- assertion asSentence Phosphatidylinositol+3-kinase+and+p38+mitogen-activated+protein+kinase+are+protein+kinases+that+regulate+the+prosurvival+effect+of+glucocorticoids+on+human+neutrophils. assertion.
- assertion asSentence Human+herpesvirus+6Binduces+p53+Ser392+phosphorylation+by+an+atypical+pathway+independent+of+casein+kinase+2+protein+and+p38+kinases. assertion.
- assertion asSentence Activation+of+p38+isoforms+by+hypertonicity+does+not+contribute+to+activation+of+TonEBP%2FOREBP+because+of+opposing+effects+of+p38alpha+and+p38delta. assertion.
- assertion asSentence Phosphorylation+of+caveolin+1+during+treatment+with+H%282%29O%282%29+is+dependent+on+p38alpha+mitogen-activated+protein+kinase. assertion.
- assertion asSentence Suppression+of+p38-stress+kinase+sensitizes+quiescent+leukemic+cells+to+anti-mitotic+drugs+by+inducing+proliferative+responses+in+them. assertion.
- assertion asSentence SARS+virus+3a+protein+modulates+the+mitochondrial+death+pathway+via+activation+of+p38+MAP+kinase. assertion.
- assertion asSentence Aspirin+induces+gastric+epithelial+barrier+dysfunction+by+activating+p38+MAPK+via+claudin-7. assertion.
- assertion asSentence Assess+the+role+of+stress+signalling+via+p38+MAP+kinase+in+the+premature+senescence+of+ataxia+telangiectasia+and+Werner+syndrome+fibroblasts. assertion.
- assertion asSentence HPV16+E7-dependent+transformation+activates+NHE1+through+a+PKA-RhoA-induced+inhibition+of+p38alpha. assertion.
- assertion asSentence Brief+intense+interval+exercise+activates+AMPK+and+p38+MAPK+signaling+and+increases+the+expression+of+PGC-1alpha+in+human+skeletal+muscle. assertion.
- assertion asSentence The+suppression+of+CX3CL1+production+by+WIN55%2C212-2+involves+inhibition+of+signaling+via+p38+MAPK. assertion.
- assertion asSentence Mitogen-activated+protein+kinase+14+blockade+induces+FoxO+nuclear+accumulation%2C+its+binding+to+promoters+and+the+expression+of+target+genes. assertion.
- assertion asSentence An+Ask1-MKK4-p38MAPK%2FJNK+pathway+reflects+adipocyte+stress+associated+with+adipose+tissue+inflammation%2C+linking+visceral+adiposity+to+whole-body+insulin+resistance+in+obesity. assertion.
- assertion asSentence Oxidative+stress+activates+ADAM17%2FTACE+and+induces+its+target+receptor+shedding+in+platelets+in+a+p38-dependent+fashion. assertion.
- assertion asSentence AT-III+directly+acts+on+platelets+and+suppresses+ADP-induced+platelet+granule+secretion+due+to+inhibiting+HSP27+phosphorylation+via+p44%2Fp42+MAPK+and+p38+MAPK. assertion.
- assertion asSentence p38alpha+blockade+induces+the+formation+of+intracellular+autophagic+vacuoles+and+reduces+growth+and+viability+of+ovarian+cancer+cells. assertion.
- assertion asSentence In+CFTRDeltaF508+cells%2C+the+extracellular+glutathione+levels+are+decreased%2C+leading+to+a+greater+sensitivity+to+reactive+oxygen+species%2C+providing+an+explanation+for+the+hyperactivation+of+the+p38+and+ERK+MAPKs+and+increased+IL-6+synthesis. assertion.
- assertion asSentence AMPK+regulates+glucocorticoid+actions+on+carbohydrate+metabolism+by+targeting+the+glucocorticoid+receptor+%28GR%29+and+modifying+transcription+of+glucocorticoid-responsive+genes+in+a+tissue-+and+promoter-specific+fashion. assertion.
- assertion asSentence The+p38+SAPK+is+recruited+to+chromatin+via+its+interaction+with+transcription+factors. assertion.
- assertion asSentence Inhibitors+of+MAPK+pathway+ERK1%2F2+or+p38+prevent+the+IL-1%7Bbeta%7D-induced+up-regulation+of+SRP72+autoantigen+in+Jurkat+cells. assertion.
- assertion asSentence Continuous+activation+of+endothelial+cells+can+cause+a+switch+of+the+p38+MAP+kinase+from+anti-angiogenic+to+pro-angiogenic+activities+in+conditions+which+link+oxidative+stress+and+autocrine+TNF+production. assertion.