Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Activation+of+p38+MAPK+in+the+placenta+of+patients+with+preeclampsia+induced+increased+levels+of+sFlt-l+and+sEng+in+maternal+serum. assertion.
- assertion asSentence The+expression+of+p38MAPK+is+up-regulated+in+salivary+adenoid+cystic+carcinoma. assertion.
- assertion asSentence Lipopolysaccharide-induced+ICAM-1+synthesis+in+human+umbilical+vein+endothelial+cells+is+regulated+by+GEF-H1%2FRhoA-dependent+signaling+pathway+via+activation+of+p38+and+NF-kappaB. assertion.
- assertion asSentence Three-dimensional+docking+in+the+MAPK+p38alpha. assertion.
- assertion asSentence By+increasing+MKP-1+expression+via+parallel+p38+MAPK-+and+CREB-mediated+pathways%2C+S1P+temporally+regulates+MAPK+signaling+pathways+by+upregulating+the+negative+feedback+controller+MKP-1. assertion.
- assertion asSentence IL-8-Rac1%2FRhoA-p38MAPK+signaling+pathway+plays+a+vital+role+in+the+IL-8-induced+endothelial+cell+migration. assertion.
- assertion asSentence A+significant+serum+tumor+marker+in+head+and+neck+squamous+cell+carcinoma. assertion.
- assertion asSentence Human+cardiac+cells+constitutively+express+M-CSF+and+its+expression+is+up-regulated+by+TNF-alpha. assertion.
- assertion asSentence CSF-1+represents+a+further+link+between+inflammation+and+cardiovascular+disease. assertion.
- assertion asSentence CRP+up-regulates+M-CSF+release+from+human+monocyte-derived+macrophages+and+human+aortic+endothelial+cells+and+increased+macrophage+proliferation. assertion.
- assertion asSentence The+different+spatiotemporal+expression+of+IL-34+and+CSF-1+allows+for+complementary+activation+of+the+CSF-1R+in+developing+and+adult+tissues. assertion.
- assertion asSentence The+GM-CSF+genotype+is+an+important+genetic+marker+predicting+an+individual%27s+predisposition+to+atopic+dermatitis. assertion.
- assertion asSentence The+GM-CSF+ARE+controls+translation+and+mRNA+decay+by+interfering+with+poly%28A%29-binding+protein-mediated+mRNA+circularization. assertion.
- assertion asSentence Profound+changes+in+the+rate+of+neutrophil+apoptosis+following+Granulocyte+macrophage+colony-stimulating+factor+signaling+occur+via+dynamic+changes+in+the+rate+of+Mcl-1+turnover+via+the+proteasome. assertion.
- assertion asSentence IL2+and+GMCSF+do+not+cause+a+cumulative+gain+in+peripheral+dendritic+cell+counts+or+an+increase+in+myeloid+BDCA-1%2B+BDCA-2-+dendritic+cell+subset+in+the+peripheral+blood. assertion.
- assertion asSentence Csf-2+regulates+invariant+natural+killer+T+%28iNKT%29+cell+effector+differentiation+during+development+by+a+mechanism+that+renders+them+competent+for+cytokine+secretion. assertion.
- assertion asSentence Human+IL-3%2FGM-CSF+knock-in+mice+support+human+alveolar+macrophage+development+and+human+immune+responses+in+the+lung. assertion.
- assertion asSentence The+dynamic+role+of+the+common+signaling+subunit+beta+c+is+to+prevent+IL5alpha+and+GM-CSF+ligand-receptor+complexes+from+rapidly+dissociating. assertion.
- assertion asSentence Ligand-binding+and+receptor+activation+are+not+critically+dependent+on+individual+N-glycosylation+sites+within+the+IL-3-+and+IL-5-receptor+common+beta-subunit. assertion.
- assertion asSentence Inhibits+spontaneous+cytochrome+c+release+and+mitochondria-dependent+apoptosis+of+myelodysplastic+syndrome+hematopoietic+progenitors. assertion.
- assertion asSentence G-CSF-mediated+antiapoptosis+is+mediated+through+protein+synthesis-dependent+mechanisms+and+involves+the+Janus+kinase-STAT+pathway. assertion.
- assertion asSentence Conformation+change+of+an+epitope+of+the+granulocyte-colony+stimulating+factor+after+binding+to+receptors. assertion.
- assertion asSentence G-CSF+is+associated+with+the+expression+of+proliferation+vascularization+in+memingioma. assertion.
- assertion asSentence Protein+kinase+C+plays+a+role+in+activation+of+granulocyte-colony+stimulating+factor+in+lung+cancer. assertion.
- assertion asSentence The+G-CSF%2FG-CSFR+autocrine%2Fparacrine+signaling+loop+significantly+promotes+survival+and+growth+of+bladder+cancer+cells. assertion.
- assertion asSentence Human+recombinant+G-CSF+enhances+angiogenesis+following+indirect+bypass+surgery%2C+a+combined+therapy+that+is+a+safe+and+easy+method+of+treatment. assertion.
- assertion asSentence Leukocyte+integrin+activation+mediates+transient+neutropenia+after+G-CSF+administration. assertion.
- assertion asSentence Non-small+cell+lung+cancer+specimens+with+G-CSF+expression+exhibited+poor+differentiation%2C+remarkable+atypia%2C+prominent+necrosis+and+infiltration+of+tumor+mass+by+neutrophils+or+emperipolesis. assertion.
- assertion asSentence Lack+of+STAT3beta+function+in+a+differentiation-competent+murine+cell+line+expressing+human+G-CSFR+argues+against+its+having+a+role+in+Kip1+expression+or+neutrophil+differentiation. assertion.
- assertion asSentence CSN2+knockdown+cells+underwent+non-apoptotic+cell+death. assertion.
- assertion asSentence CK1alphaLS+and+hnRNP-C+represent+conserved+components+of+a+vertebrate-specific+H%282%29O%282%29-responsive+nuclear+signaling+pathway. assertion.
- assertion asSentence Phosphorylation+of+parkin+by+casein+kinase+I+and+cdk5+decreases+parkin+solubility%2C+leading+to+its+aggregation+and+inactivation. assertion.
- assertion asSentence Inhibition+of+HCKID+alters+mitotic+spindle+formation+and+induces+apoptosis+in+trophoblast+cells. assertion.
- assertion asSentence The+circadian+regulatory+proteins+BMAL1+and+cryptochromes+are+substrates+of+casein+kinase+Iepsilon. assertion.
- assertion asSentence Casein+kinase+I+epsilon+is+an+upstream+kinase+regulating+in+vivo+phosphorylation+of+topoisomerase+IIalpha+at+Ser-1106. assertion.
- assertion asSentence Response+of+cancer+cells+to+molecular+interruption+of+the+CK2+signal. assertion.
- assertion asSentence V-Src-dependent+down-regulation+of+the+Ste20-like+kinase+SLK+through+casein+kinase+II. assertion.
- assertion asSentence CK2+is+required+for+the+assembly+and+cycling+of+Wnt-enhancer+complexes+in+vivo. assertion.
- assertion asSentence CK2-dependent+phosphorylation+controls+the+nuclear+localization%2C+aggregation+and+stability+of+ataxin-3. assertion.
- assertion asSentence Protein+kinase+CK2alpha+plays+an+important+role+in+the+proliferation+and+invasion+of+nasopharyngeal+carcinoma. assertion.
- assertion asSentence The+Arabidopsis+co-chaperone+protein+p23+is+a+CK2+target. assertion.
- assertion asSentence Inhibition+of+CK2+activity+by+three+different+inhibitors+led+to+a+down-regulation+of+the+level+of+cdc25C. assertion.
- assertion asSentence The+human+adenovirus+type+5+E1B+protein+is+phosphorylated+by+protein+kinase+CK2. assertion.
- assertion asSentence Protein+kinase+CK2+co-localizes+with+gamma-H2AX+to+sites+of+genetic+lesions+and+modulation+of+its+expression+levels+affects+the+cellular+DNA+damage+response. assertion.
- assertion asSentence Mapping+of+the+interaction+domain+of+the+protein+kinase+CKII+beta+subunit+with+target+proteins. assertion.
- assertion asSentence Consequences+of+CK2+signaling+to+the+nuclear+matrix. assertion.
- assertion asSentence Threonine+at+amino+acid+%28aa%29+770+and+serine+at+aa+854+to+855+of+RIG-I+are+phosphorylated+by+casein+kinase+II+%28CK2%29+in+the+resting+state+of+the+cell+and+dephosphorylated+when+cells+are+infected+by+RNA+virus. assertion.
- assertion asSentence Versican+demonstrated+distinctive+localization+relative+to+nodules+within+calcified+aortic+valves. assertion.
- assertion asSentence Hyaluronan+and+versican+play+a+role+in+T-cell+trafficking+and+function+in+inflamed+tissues. assertion.
- assertion asSentence Co-expression+and+interaction+of+NG2+and+galectin-3+in+human+glioma+cells+establish+a+molecular+basis+for+the+NG2%2Fgalectin-3+interaction. assertion.
- assertion asSentence Associated+with+exudative+age+related+macular+degeneration. assertion.
- assertion asSentence A+more+sensitive+serum+marker+than+creatinine+of+glomerular+filtration+rate+fter+kidney+transplantation. assertion.
- assertion asSentence Elastin-+and+collagen-rich+human+carotid+plaques+have+increased+levels+of+the+cysteine+protease+inhibitor+cystatin+C. assertion.
- assertion asSentence Plasma+cystatin+C+is+better+than+serum+creatinine+in+detecting+stage+3+CKD+in+patients+with+AN. assertion.
- assertion asSentence Cystatin+C+through+this+effect+can+act+as+an+immunomodulatory+molecule. assertion.
- assertion asSentence CST3+genotype+an+dlow+cystatin+c+cerebrospinal+fluid+are+associated+with+dementia+in+Lewy+body+disease. assertion.
- assertion asSentence The+diagnostic+accuracy+of+various+cystatin+C+equations+varies+with+GFR+in+children. assertion.
- assertion asSentence Serum+CysC+is+a+useful+marker+for+detecting+significant+renal+dysfunction+in+patients+with+cirrhotic+ascites+and+normal+serum+creatinine+levels. assertion.
- assertion asSentence Cystatin+C+is+a+good+predictor+of+hepatorenal+syndrome+and+survival+in+patients+with+cirrhosis+who+have+normal+serum+creatinine+levels. assertion.
- assertion asSentence Elevated+cystatin+C%2C+together+with+hs-CRP+and+homocysteine%2C+is+an+independent+risk+factor+that+is+important+in+the+prognosis+of+patients+with+systolic+heart+failure. assertion.
- assertion asSentence Compared+with+its+homologues%2C+cystatin+D+presents+an+unusual+inhibition+profile+with+a+preferential+inhibition+cathepsin+S+%3E+cathepsin+H+%3E+cathepsin+L+and+no+inhibition+of+cathepsin+B+or+pig+legumain. assertion.
- assertion asSentence Cystatin+M+suppresses+the+malignant+phenotype+of+MDA-MB-435S+cells. assertion.
- assertion asSentence Methylation-dependent+epigenetic+silencing+of+CST6+represents+an+important+mechanism+for+loss+of+CST6+during+breast+tumorigenesis+and%2For+progression+to+metastasis. assertion.
- assertion asSentence The+Hinge+domain+is+necessary+for+CstF-64+interaction+with+CstF-77+and+consequent+nuclear+localization. assertion.
- assertion asSentence The+Hinge+domain+is+necessary+for+CstF-64+interaction+with+CstF-77+and+consequent+nuclear+localization. assertion.
- assertion asSentence In+T-cell+acute+lymphoblastic+leukemia%2C+alternative+t%285%3B14%29%28q35%3Bq32.2%29+forms+effect+dysregulation+of+either+TLX3+or+NKX2-5+homeobox+genes+at+5q35+by+juxtaposition+with+14q32.2+breakpoints+dispersed+across+the+BCL11B+downstream+genomic+desert. assertion.
- assertion asSentence Variants+within+the+cardiac+enhancer+in+the+NKX2-5+gene+is+not+associated+with+ventricular+septal+defects. assertion.
- assertion asSentence NY-ESO-1+119-143+is+a+promiscuous+major+histocompatibility+complex+class+II+T-helper+epitope+recognized+by+Th1-+and+Th2-type+tumor-reactive+CD4%2B+T+cells. assertion.
- assertion asSentence NY-ESO-1+overexpression+increases+as+the+malignancy+grade+of+the+astrocytic+tumors+increases. assertion.
- assertion asSentence The+Golgi+mitotic+checkpoint+is+controlled+by+BARS-dependent+fission+of+the+Golgi+ribbon+into+separate+stacks+in+G2. assertion.
- assertion asSentence Infectious+Ad3+macropinocytosis+required+viral+activation+of+p21-activated+kinase+1+%28PAK1%29+and+the+C-terminal+binding+protein+1+of+E1A+%28CtBP1%29%2C+recruited+to+macropinosomes. assertion.
- assertion asSentence CtBP1+down-regulates+Brca1+and+E-cadherin+genes+in+human+breast+cancer. assertion.
- assertion asSentence Plasma+cardiotrophin-1+is+associated+with+progression+of+heart+failure+in+hypertensive+patients. assertion.
- assertion asSentence Hypoxia+increased+cardiotrophin-1+levels+in+cardiac+cells+through+a+direct+regulation+of+CT-1+promoter+by+HIF-1alpha%2C+protecting+cells+from+apoptosis. assertion.
- assertion asSentence The+NH2-terminal+CTGF+fragment+content+is+increased+in+the+vitreous+of+patients+with+proliferative+diabetic+retinopathy. assertion.
- assertion asSentence Simvastatin+through+a+Rho+signaling+mechanism+in+lung+fibroblasts+can+modulate+CTGF+expression+and+interaction+with+TGF-beta. assertion.
- assertion asSentence MMP-2+processing+of+HARP+and+CTGF+released+vascular+endothelial+growth+factor+%28VEGF%29+from+angiogenic+inhibitory+complexes. assertion.
- assertion asSentence Regulation+of+CCN2%2FCTGF+and+related+cytokines+in+cultured+peritoneal+cells+under+conditions+simulating+peritoneal+dialysis. assertion.
- assertion asSentence High+glucose-induced+CTGF+expression+is+mediated+through+the+active+SGK1+pathway+in+mesangial+cells. assertion.
- assertion asSentence Role+of+connective+tissue+growth+factor+and+its+interaction+with+basic+fibroblast+growth+factor+and+macrophage+chemoattractant+protein-1+in+skin+fibrosis. assertion.
- assertion asSentence Downregulation+of+connective+tissue+growth+factor+by+three-dimensional+matrix+enhances+ovarian+carcinoma+cell+invasion. assertion.
- assertion asSentence Hypoxia+inhibits+CTGF+synthesis+in+human+proximal+tubular+epithelial+cells%2C+involving+HIF-1alpha. assertion.
- assertion asSentence CTGF+is+involved+in+the+wound-healing+process+and+plays+an+important+role+in+the+pathogenesis+of+intraocular+proliferative+diseases. assertion.
- assertion asSentence Exposure+to+hypoxia+decreased+CTGF+gene+expression+in+cultured+human+tubular+epithelial+cells. assertion.
- assertion asSentence Fascin+regulates+the+proliferation+and+invasiveness+of+ESCC+cells+by+modulating+the+expression+of+CTGF+and+CYR61+via+TGF-beta+pathway. assertion.
- assertion asSentence CTGF+cooperates+with+FN+in+enhancing+the+attachment+and+migration+of+corneal+epithelial+cells. assertion.
- assertion asSentence Myofibroblast+transformation+induced+by+transforming+growth+factor-beta1+is+dependent+on+CTGF+activation. assertion.
- assertion asSentence CCN2+gene+polymorphism+is+a+prognostic+risk+factor+for+cardiovascular+morbidity+and+mortality+in+hemodialysis+patients. assertion.
- assertion asSentence CTGF+expression+in+early+pregnancy+decidua+is+regulated+by+PROK1%2C+via+activation+of+the+Gq%2C+PLC%2C+cSrc%2C+EGFR%2C+MAPK%2FERK+kinase+pathway+and+has+a+role+in+cell+adhesion. assertion.
- assertion asSentence Activation+of+liver+cells+causes+an+increased+synthesis+of+TGF-beta1+followed+by+a+CTGF+overproduction+in+various+polymorphic+hepatic+structures%2C+in+accordance+with+the+degree+of+fibrosis. assertion.
- assertion asSentence Increased+expression+of+CTGF+is+associated+with+hypertrophy+of+the+ligamentum+flavum+in+patients+with+lumbar+spinal+stenosis. assertion.
- assertion asSentence CTLA4+gene+region+is+associated+with+genetic+susceptibility+to+celiac+disease+in+UK+families. assertion.
- assertion asSentence CTLA-4+is+a+predisposing+gene+for+celiac+disease+in+an+Italian+population+with+a+prominent+role+in+patients+not+carrying+the+high-risk+human+leukocyte+antigen-DQ2+molecules. assertion.
- assertion asSentence Association+of+variations+of+the+CTLA4+promoter+region+with+type+1+diabetes. assertion.
- assertion asSentence Susceptibility+to+autoimmune+hepatitis-1+and+-2+in+Brazilian+patients+is+not+influenced+by+exon+1+CTLA-4+gene+polymorphisms+at+position+49. assertion.
- assertion asSentence The+CTLA4+%2B49+A%2FG%2AG-CT60%2AG+haplotype+is+associated+with+susceptibility+to+multiple+sclerosis+in+Flanders. assertion.
- assertion asSentence Exon-1+polymorphism+of+CTLA4+gene+is+not+associated+with+systemic+sclerosis+in+Iranian+patients. assertion.
- assertion asSentence CTLA-4+gene+is+involved+in+predisposition+to+inflammatory+arthropathies+in+the+Northern+Irish+population. assertion.
- assertion asSentence Kidney+graft+rejection+is+greater+in+CTLA4+single+nucleotide+polymorphism. assertion.
- assertion asSentence There+us+an+assoiciation+of+CTLA-4+gene+promoter+polymorphisms+with+systemic+sclerosis+in+the+Iranian+population. assertion.