Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP188066.RAvSr5nGWcrWZIKKzZl1_Hpl4YiCEbZW-g-Xa8CUzdTVY130_assertion description "[Interestingly, p34(SEI-1) expression is absent or weak in normal tissues but is strongly expressed in tissues obtained from patients with breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188066.RAvSr5nGWcrWZIKKzZl1_Hpl4YiCEbZW-g-Xa8CUzdTVY130_provenance.
- NP188067.RAtqOSHlajLJWgsVEX4pYy977Nvtucchx3afsxVElARH8130_assertion description "[CCDC40 localizes to motile cilia and the apical cytoplasm and is required for axonemal recruitment of CCDC39, disruption of which underlies a similar variant of PCD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188067.RAtqOSHlajLJWgsVEX4pYy977Nvtucchx3afsxVElARH8130_provenance.
- NP188070.RAh-GsI_FcIWA0-WBWYyh9fmGfRV5V19_P1yOTr9aIpQQ130_assertion description "[In the present study, we report a novel rat model for type 2 diabetes: rats transgenic for human IAPP (the HIP rat).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188070.RAh-GsI_FcIWA0-WBWYyh9fmGfRV5V19_P1yOTr9aIpQQ130_provenance.
- NP188073.RAsASDCtm4HRMJLh45QGQ3TxMIYVIx4N8Jwu-uAtSs_1c130_assertion description "[Patients with ADHD and with a history of nicotine abuse both displayed lower values of DAT density in [99mTc]TRODAT-1 SPECT than non-smokers with ADHD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188073.RAsASDCtm4HRMJLh45QGQ3TxMIYVIx4N8Jwu-uAtSs_1c130_provenance.
- NP188074.RAoevU1mxav55yP1PdOa-9FySmVGBtEAI7q3aZT_EZLwQ130_assertion description "[We attempted to describe, in a series of clear cell renal cell carcinoma (RCC), the relationship between CAIX expression, VHL gene mutations, tumor characteristics and outcome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188074.RAoevU1mxav55yP1PdOa-9FySmVGBtEAI7q3aZT_EZLwQ130_provenance.
- NP188075.RAvfNj53L0zdcBsK-2oiI2ucs6pGpxDf9uAKgTNU2MJZY130_assertion description "[Six polymorphisms evaluated in the combined set showed significantly modified breast cancer risk per allele in the joint analysis, including SNPs in CYBA (encoding a subunit of the NADPH oxidase: rs3794624), MT2A (metallothionein 2A: rs1580833), TXN (thioredoxin: rs2301241), and in TXN2 (thioredoxin 2: rs2267337, rs2281082, rs4821494).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188075.RAvfNj53L0zdcBsK-2oiI2ucs6pGpxDf9uAKgTNU2MJZY130_provenance.
- NP188079.RAmeNJv1KnixqtC0N-xMKwDWlE4-FQI3aqsbxOvLJh0AU130_assertion description "[However, the BV8 downstream signaling pathway(s) intrinsic to myeloid cells crucial for angiogenesis, and potentially also for development of cancers of myeloid origin, remains largely unknown.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188079.RAmeNJv1KnixqtC0N-xMKwDWlE4-FQI3aqsbxOvLJh0AU130_provenance.
- NP188080.RAvjnarqJKtPmwuVFE9Zp06ov9UJ1YeeOhutg3kK53ZhE130_assertion description "[Population studies conducted in various countries have demonstrated an association between single nucleotide polymorphisms (SNPs) in ApoA5 and the increased risk to cardiovascular disease and metabolic syndrome (including diabetes and obesity).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188080.RAvjnarqJKtPmwuVFE9Zp06ov9UJ1YeeOhutg3kK53ZhE130_provenance.
- NP188081.RAtdplN2ogA-EO6-XEtSgGDXdWDB2TIzwWizSSezOsaeU130_assertion description "[In this longitudinal observation, we further explored the impact of human leukocyte antigen (HLA) class I/II alleles on MS outcomes, and we tested the hypothesis that HLA DRB1*1501 might uncover different strata of MS subjects harboring distinct MHC allele associations with magnetic resonance imaging (MRI) measures.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188081.RAtdplN2ogA-EO6-XEtSgGDXdWDB2TIzwWizSSezOsaeU130_provenance.
- NP188082.RAqrch50Zl_2xn2lJavvSN1RtPRENnaGh8Z3vYNK87bxM130_assertion description "[Overexpression of NANOG in gestational trophoblastic diseases: effect on apoptosis, cell invasion, and clinical outcome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188082.RAqrch50Zl_2xn2lJavvSN1RtPRENnaGh8Z3vYNK87bxM130_provenance.
- NP188083.RAvrJfSZcMH21OXTk8gxMQVb6AVMSQ0jAFpvZrvN2x-eQ130_assertion description "[GST pi was also variably expressed in human tumors, with the lowest relative levels occurring in lymphoma and breast cancer and the highest levels found in lung cancer and head and neck tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188083.RAvrJfSZcMH21OXTk8gxMQVb6AVMSQ0jAFpvZrvN2x-eQ130_provenance.
- NP188086.RAp3g29pUZZ0fFG_VAQV6VNSudnnMt6SCwtpOggSi-BRI130_assertion description "[Leigh syndrome associated with mitochondrial complex I deficiency due to novel mutations In NDUFV1 and NDUFS2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188086.RAp3g29pUZZ0fFG_VAQV6VNSudnnMt6SCwtpOggSi-BRI130_provenance.
- NP188089.RAqTu1eAzyhwb2p1p_ZH210GW0UDcMVA640LoFdn7tFJw130_assertion description "[Mean HER-2 mRNA expression was higher (P < 0.05) in AD-CaP than AI-CaP (22,080 versus 15,496 HER-2 copies).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188089.RAqTu1eAzyhwb2p1p_ZH210GW0UDcMVA640LoFdn7tFJw130_provenance.
- NP188091.RAqlJ2BiQGjKUih7hiq-77SutAEWTzL4tq-aFBwOXu1aY130_assertion description "[Population studies on aCL in diseases other than primary APS indicate that aCL are associated with DR4, DR7, and DRw53, at least when they are found in patients with systemic lupus erythematosus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188091.RAqlJ2BiQGjKUih7hiq-77SutAEWTzL4tq-aFBwOXu1aY130_provenance.
- NP188095.RAvCw5uARZNzIOiMyO0HUUspoSpsfGHgkd_5XghcFXnzo130_assertion description "[Persistent elevation of hepatocyte growth factor activator inhibitors in cholangiopathies affects liver fibrosis and differentiation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188095.RAvCw5uARZNzIOiMyO0HUUspoSpsfGHgkd_5XghcFXnzo130_provenance.
- NP188099.RAojZ2OPJHc0GzbFBWQToymgnnnJKwlTC5R9JTCoKfhQE130_assertion description "[Furthermore, HGF concentrations in metastatic cancer tissues were significantly higher than those of non-metastatic cancer tissues and normal gingiva (p < 0.01).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188099.RAojZ2OPJHc0GzbFBWQToymgnnnJKwlTC5R9JTCoKfhQE130_provenance.
- NP188100.RAnc1eCssWQfMcTV1_6Y4XnPT2abZIiePBZHUOtuTiBoA130_assertion description "[Hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) gene mutation have been postulated as a possible cause of recurrent miscarriage (RM).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188100.RAnc1eCssWQfMcTV1_6Y4XnPT2abZIiePBZHUOtuTiBoA130_provenance.
- NP188101.RAl_RZ8RKU0huJYinkDzMVM8HmBwBqXvYD8ltb_xXQyiM130_assertion description "[In the present study of 27 adult male Bangladeshi patients with dysentery (14 cases caused by Shigella Dysenteriae 1 and 13 cases caused by Shigella flexneri), the changes in the TCR Vbeta repertoire of peripheral blood CD4+ and CD8+ T-cell subsets have been analyzed with a panel of nine anti-Vbeta monoclonal antibodies by flow cytometry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188101.RAl_RZ8RKU0huJYinkDzMVM8HmBwBqXvYD8ltb_xXQyiM130_provenance.
- NP188108.RAs_czmdEQcflvEq_Bp0I_CAtzALBKl1dsClLtY8uC8fs130_assertion description "[Nuclear glucocorticoid receptor expression was found in most clear cell renal cell carcinomas (66%), in 26% of papillary renal cell carcinomas, and in only 6% of chromophobe renal cell carcinomas and 14% of oncocytoma (P < .005).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188108.RAs_czmdEQcflvEq_Bp0I_CAtzALBKl1dsClLtY8uC8fs130_provenance.
- NP188116.RAtaRl47yBT2AV1tgkveCjVMJ-7CzjopBpapSU8N05RDs130_assertion description "[Current research suggests that depression and anxiety may be common problems in women with the fragile X (FMR1) premutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188116.RAtaRl47yBT2AV1tgkveCjVMJ-7CzjopBpapSU8N05RDs130_provenance.
- NP188117.RAsbhkWC7cJ4Mv01jPToODrcsh7WcZURJJQ_TSJKAM2pA130_assertion description "[A 57-year-old white woman had serum ferritin 793 ng/mL, HFE C282Y homozygosity, elevated serum angiotensin-converting enzyme (ACE) levels, 3+ hepatocyte iron, cirrhosis, hepatic granulomas, and portal hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188117.RAsbhkWC7cJ4Mv01jPToODrcsh7WcZURJJQ_TSJKAM2pA130_provenance.
- NP188120.RAlDh77DFB5zn0lmmxF-NZqVluY5rQOWV3oc02_7E9E4I130_assertion description "[TNF 2 allele was associated with GD (p = 0.0011), whereas TNF 1, HLA-DR11 and DR12 (p = 0.0039, p = 0.00089 and p = 0.0056, respectively) were rather implicated in HT pathogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188120.RAlDh77DFB5zn0lmmxF-NZqVluY5rQOWV3oc02_7E9E4I130_provenance.
- NP188121.RAvp_p-BPOjF5l9CxMd181tZyF7UamXGhhHohk2JK29LM130_assertion description "[These results suggest that pharmacological inhibition of AR will be beneficial during ischemia and in some forms of heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188121.RAvp_p-BPOjF5l9CxMd181tZyF7UamXGhhHohk2JK29LM130_provenance.
- NP188122.RAjABIudsywcpt2stDoeaskKz9dicKhikiljVZlRa-8Is130_assertion description "[Like its close relatives UCP1 and UCP3, UCP2 uncouples proton entry in the mitochondrial matrix from ATP synthesis and is therefore a candidate gene for obesity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188122.RAjABIudsywcpt2stDoeaskKz9dicKhikiljVZlRa-8Is130_provenance.
- NP188123.RArfTVG0ctiFNuWbfvuGzQUGn4UjwYviLjMG54YS2rHKQ130_assertion description "[We tested this hypothesis by examining the effects of combined MDM2 polymorphisms and somatic p53 mutations on 351 oral squamous cell carcinomas (OSCCs) associated with areca quid chewing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188123.RArfTVG0ctiFNuWbfvuGzQUGn4UjwYviLjMG54YS2rHKQ130_provenance.
- NP188124.RAlsscMG2fLpVAy9yACkhHrCAOSTZgpCk28zvNstlqZS0130_assertion description "[The gastrointestinal peptides gastrin and cholecystokinin (CCK) stimulate growth of human pancreatic cancer through a CCK-B/gastrin- like receptor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188124.RAlsscMG2fLpVAy9yACkhHrCAOSTZgpCk28zvNstlqZS0130_provenance.
- NP188132.RAgMxQIwiU7I1Zmts3cemKEuQ6XyCmWMrhOZeI3-Qa4kg130_assertion description "[A novel missense mutation (Leu46Val) of PAX6 found in an autistic patient.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188132.RAgMxQIwiU7I1Zmts3cemKEuQ6XyCmWMrhOZeI3-Qa4kg130_provenance.
- NP188139.RAknmQ4V6nHkxX4hafD-9uVwH-kIdnouGnYm9B-4pWeN4130_assertion description "[Several studies support the dysbindin (dystrobrevin binding protein 1) gene (DTNBP1) as a susceptibility gene for schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188139.RAknmQ4V6nHkxX4hafD-9uVwH-kIdnouGnYm9B-4pWeN4130_provenance.
- NP188145.RArtNWdO42dm3v7rzQM_I3arg7hJltBaarbaD3mSx6lsg130_assertion description "[There are other convincing examples in the last 12 months: age-related macular degeneration (CFH), type 1 diabetes (IL2RA, also known as CD25) and type 2 diabetes (TCF7L2).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188145.RArtNWdO42dm3v7rzQM_I3arg7hJltBaarbaD3mSx6lsg130_provenance.
- NP188154.RAhIWmSk8DyIPY6jG6st5Jw_iQbp9THAl-JPiB992suVc130_assertion description "[We studied 602 patients with previous VTE: the incidence of first recurrence in the absence of anticoagulation was retrospectively estimated in 64 patients with deficiency of antithrombin (AT, n=14), protein C (PC, n=28), or protein S (PS, n=22) and 538 with no known defect, who acted as the reference group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188154.RAhIWmSk8DyIPY6jG6st5Jw_iQbp9THAl-JPiB992suVc130_provenance.
- NP188158.RAgVo5CHwEseMqfimM_S3Q0z4gbZ_NIQD5tSalyzJvcDg130_assertion description "[To investigate its function, we searched for PKP3-interacting proteins and identified dynamin 1-like, which was also activated in NSCLC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188158.RAgVo5CHwEseMqfimM_S3Q0z4gbZ_NIQD5tSalyzJvcDg130_provenance.
- NP188159.RArBt_yFfTnC_IAFNEZeb6Ebq1JmB3e5fptTZRMsCaOSM130_assertion description "[Parallel fluorescence in situ hybridization and immunohistochemical analyses of EEF1A2 and KCIP-1 in tissue microarrays from patients with lung adenocarcinoma showed that gene amplification was associated with high protein expression for both genes and that protein overexpression was related to tumor grade, disease stage, Ki-67 expression, and a shorter survival of patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188159.RArBt_yFfTnC_IAFNEZeb6Ebq1JmB3e5fptTZRMsCaOSM130_provenance.
- NP188160.RAmnpTpS--oSlZxMsa1ZGjINfnRWWFUoiVZZUB9PEyQiA130_assertion description "[In the dl-PFC of alcoholics, methylation levels of the C, non-risk variant of 3'-untranslated region (3'-UTR) SNP (rs2235749; C > T) were increased, and positively correlated with dynorphins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188160.RAmnpTpS--oSlZxMsa1ZGjINfnRWWFUoiVZZUB9PEyQiA130_provenance.
- NP188166.RAuR__S5VEWpenYXbdrcEsjNYNnX84Vx4PT4sKZ9MlVdc130_assertion description "[OncoGenex Technologies Inc in collaboration with Isis Pharmaceuticals Inc is developing OGX-011, an intravenously administered clusterin-inhibiting antisense oligonucleotide, to potentially sensitize solid tumors that are resistant to conventional cancer therapeutics.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188166.RAuR__S5VEWpenYXbdrcEsjNYNnX84Vx4PT4sKZ9MlVdc130_provenance.
- NP188167.RAljQY8npmYga4D8vmqdbftwF5kC8E7vfEPkvb5UMhENw130_assertion description "[Our findings demonstrate that widespread increased p53 expression is present in HAD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188167.RAljQY8npmYga4D8vmqdbftwF5kC8E7vfEPkvb5UMhENw130_provenance.
- NP188175.RAuJgidv2qwFJSS-LeTfxn2qi7fDiCwWU-umueB_AqZoM130_assertion description "[MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188175.RAuJgidv2qwFJSS-LeTfxn2qi7fDiCwWU-umueB_AqZoM130_provenance.
- NP188177.RAmscWxyipiXLixDqJNWD6pbMv6-BVOUMM_CVQoGIRi30130_assertion description "[In this study we have analyzed the balance of expression of mRNAs encoding extracellular matrix components (collagens I, III and IV, laminin, fibronectin), extracellular matrix-degrading metalloproteinases (MMP-1, -2, -3 and -9) and tissue inhibitors of metalloproteinases (TIMP-1 and -2) in pancreatic cancer and control pancreatic tissue by Northern-blot analysis and mRNA in situ hybridization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188177.RAmscWxyipiXLixDqJNWD6pbMv6-BVOUMM_CVQoGIRi30130_provenance.
- NP188185.RAtsAhQOH_zjurVVTJ1Y8pfx6l2OgSFlllMAlz2e3qvjI130_assertion description "[Optimizing the APC gene mutation analysis in archival colorectal tumor tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188185.RAtsAhQOH_zjurVVTJ1Y8pfx6l2OgSFlllMAlz2e3qvjI130_provenance.
- NP188191.RAhcRgAY6NVxPRKebU5-HT6h761DHJNQ6JP_nzuerVwgQ130_assertion description "[Here, we show that high-level HOXC9 expression is associated with neuroblastoma differentiation and is prognostic for better survival in neuroblastoma patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188191.RAhcRgAY6NVxPRKebU5-HT6h761DHJNQ6JP_nzuerVwgQ130_provenance.
- NP188193.RAlyVE8Hukoqog8EBPptz1Yd_S2jPQMQPD9WFlQzcEAps130_assertion description "[COX-2 and atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188193.RAlyVE8Hukoqog8EBPptz1Yd_S2jPQMQPD9WFlQzcEAps130_provenance.
- NP188194.RApZ_rOSP5YLmRvx8obw5OJMimr7alFxYjXkLQm2yXyQ4130_assertion description "[In ARLs loss of A20 may be an alternative mechanism of NF-κB activation in the absence of latent membrane protein 1 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188194.RApZ_rOSP5YLmRvx8obw5OJMimr7alFxYjXkLQm2yXyQ4130_provenance.
- NP188198.RAk8Xj6ysMCxMxsvL-NNBZdZwCiF2p3ch61UwUvy1WYGA130_assertion description "[We also analyzed the NPM1 mutation in 142 acute leukemias, including 105 AMLs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188198.RAk8Xj6ysMCxMxsvL-NNBZdZwCiF2p3ch61UwUvy1WYGA130_provenance.
- NP188201.RApeKG3RzL9WdUM8Y6DYT72QDSq-wk0zxwNzm-9ktNowY130_assertion description "[The stimulation with IFNgamma+TNFalpha induced a synergistic CXCL10 release in both cell types; however, a secretion more than ten times higher was induced in PTCs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188201.RApeKG3RzL9WdUM8Y6DYT72QDSq-wk0zxwNzm-9ktNowY130_provenance.
- NP188204.RAtB_X1btB09f9TtvgBG1d8ucD1raYrqzFOPF9tsP3gh4130_assertion description "[In S3B cells, no active MAP kinase could be detected in response to E2, suggesting that signalling through the MAP kinase is not the major pathway in the E2-mediated growth stimulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188204.RAtB_X1btB09f9TtvgBG1d8ucD1raYrqzFOPF9tsP3gh4130_provenance.
- NP188207.RAvTtDgUa4V1sgA_pfzkjyfOWauIE0MmrN0cgFc_Ovfc4130_assertion description "[A primary target leading to low-grade papillary superficial bladder tumors resides on chromosome 9, while p53 gene alterations are commonly seen in flat carcinoma in situ.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188207.RAvTtDgUa4V1sgA_pfzkjyfOWauIE0MmrN0cgFc_Ovfc4130_provenance.
- NP188212.RAn_54QqIYPmGOme_mGQSWr7ug7Xf5_qAyZ6REIyIJ45g130_assertion description "[In summary, we have added new evidence supporting the association between ZNF804A and schizophrenia in our Han Chinese sample.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188212.RAn_54QqIYPmGOme_mGQSWr7ug7Xf5_qAyZ6REIyIJ45g130_provenance.
- NP188213.RAt7qudPVh9M1CoKGYgnEiqq7xAZE4cv-uuW_EtXmmego130_assertion description "[Our study found no link between polymorphisms in APOE, p53, and p21 genes and POAG in Turkish patients, although a larger sample is required to elucidate the role of these polymorphisms in the pathogenesis and course of glaucoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188213.RAt7qudPVh9M1CoKGYgnEiqq7xAZE4cv-uuW_EtXmmego130_provenance.
- NP188218.RAhDVziMnLhSCO2V539wpBjbxA6dzNiYIgBpTbgKMYwUk130_assertion description "[Recent reports indicate that DNA methylation is regulated in part by the ERK pathway, and that ERK pathway signaling is diminished in lupus T cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188218.RAhDVziMnLhSCO2V539wpBjbxA6dzNiYIgBpTbgKMYwUk130_provenance.
- NP188221.RAmboEFr4SOGkYY2Vo9npcdRCsgDYFAyG_FOW2RIpkDHo130_assertion description "[Pathological neuronal inclusions of the 43-kDa TAR DNA-binding protein (TDP-43) are implicated in dementia and motor neuron disorders; however, the molecular mechanisms of the underlying cell loss remain poorly understood.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188221.RAmboEFr4SOGkYY2Vo9npcdRCsgDYFAyG_FOW2RIpkDHo130_provenance.
- NP188222.RAgApcMoseU-7EsI2Chl-63BK3AXnBh3UdQPmXOjdKiU0130_assertion description "[Analysis of CD28 and CTLA-4 gene polymorphisms in Turkish patients with Behcet's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188222.RAgApcMoseU-7EsI2Chl-63BK3AXnBh3UdQPmXOjdKiU0130_provenance.
- NP188226.RAkAprtDiPdyaj5-7mq3CaK6S72RhksFTwCgweuiNVYgs130_assertion description "[It is most likely that loss of function of MUTYH in stem or progenitor cells in the intestinal epithelium of MUTYH-associated polyposis patients results in escape from programmed cell death; however, accumulated 8-oxoguanine causes various mutations in APC or KRAS genes in these proliferative cells, thereby promoting tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188226.RAkAprtDiPdyaj5-7mq3CaK6S72RhksFTwCgweuiNVYgs130_provenance.
- NP188230.RAuRzs2cIm1Kx0-waKkeOCb5acsriEsaCywQhevZXBpMw130_assertion description "[An unusual form of X chromosome aneuploidy, 47,XX,psu dic(X)(p11.2), was found during an evaluation for short stature of a prepubertal girl.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188230.RAuRzs2cIm1Kx0-waKkeOCb5acsriEsaCywQhevZXBpMw130_provenance.
- NP188245.RAquUUtNvumRTp52Qi18yQic7U93-6D3f-mtJDvf-Mj2E130_assertion description "[Besides the well-known TSGs including PTEN, DMBT1, p16, p15, p53 and RB, multiple unknown TSGs associated with GBM may be present on the commonly deleted regions detected in the present study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188245.RAquUUtNvumRTp52Qi18yQic7U93-6D3f-mtJDvf-Mj2E130_provenance.
- NP188248.RApgkuezqgYEyIDpJ22zsTJNLFdTNgHFdiWHG5QuVx0uc130_assertion description "[We describe the analysis of the chromosome breakpoints in a patient with congenital bilateral isolated ptosis and a de novo balanced translocation 46,XY,t(1;8)(p34.3;q21.12).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188248.RApgkuezqgYEyIDpJ22zsTJNLFdTNgHFdiWHG5QuVx0uc130_provenance.
- NP188251.RAuPk7DMocyIe8dLDIY_7Urn7dhxEblYrEhGzrzSrn1hs130_assertion description "[Despite the sharp contrast between T-ALL and B-ALL in CD66 reactivity, CEACAM patterns were comparable, and only minor differences for CEACAM1 and CEACAM8 were detected.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188251.RAuPk7DMocyIe8dLDIY_7Urn7dhxEblYrEhGzrzSrn1hs130_provenance.
- NP188252.RAjxRl-a2bhBM0wcM34JgsVVjcpMTaS7-NZtUnaU1MWSE130_assertion description "[Association of DNA repair gene XRCC1 and XPD polymorphisms with genetic susceptibility to gastric cancer in a Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188252.RAjxRl-a2bhBM0wcM34JgsVVjcpMTaS7-NZtUnaU1MWSE130_provenance.
- NP188254.RAgkwk_rdyhzdKIyTHMimRrFu81fRR70o63QEcP2RK9Fk130_assertion description "[These data suggested that SYT-SSX fusion type is associated with tumor cell proliferative activity and prognosis of patients who have SS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188254.RAgkwk_rdyhzdKIyTHMimRrFu81fRR70o63QEcP2RK9Fk130_provenance.
- NP188258.RArWhQcughTtmsIRaPY5iokRZKtkrifOOaf-xcAzHOikA130_assertion description "[We have purified and partially sequenced a protein from the adventitia of the human aorta (aortic aneurysm antigenic protein 40 kDa; AAAP-40) that has homologies to bovine aortic microfibril-associated glycoprotein (MAGP-36).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188258.RArWhQcughTtmsIRaPY5iokRZKtkrifOOaf-xcAzHOikA130_provenance.
- NP188260.RAgSm1DAvw-Yv3MBZwbtg--ARCfGU2ztag8fb7zxAiBRU130_assertion description "[We tested the association between clinical characteristics and ERP, and estimated sibling recurrence risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188260.RAgSm1DAvw-Yv3MBZwbtg--ARCfGU2ztag8fb7zxAiBRU130_provenance.
- NP188262.RAqAzhuWYtmqD5hlL2a-FjUmR31skTBv3rfSXbOCWSLm0130_assertion description "[The NF2 gene is mutated in constitutional DNA of affected patients from NF2 families and in sporadic cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188262.RAqAzhuWYtmqD5hlL2a-FjUmR31skTBv3rfSXbOCWSLm0130_provenance.
- NP188279.RAmwbboE27LMkdvXLbklMSCRdGzyRzSGtYvrGXXKghnF0130_assertion description "[Kruppel-like transcription factor 6 (KLF6), which is associated with negative control of cell proliferation, is downregulated in many cancers, including NSCLC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188279.RAmwbboE27LMkdvXLbklMSCRdGzyRzSGtYvrGXXKghnF0130_provenance.
- NP188286.RAoQ9ZdoAGgmM0kPx1dB5OHf4WUQ1TKAuzAlUgaeG6Ars130_assertion description "[The regulators of a key metastasis gene PRL-3 in colorectal cancer (CRC) are still largely unknown.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188286.RAoQ9ZdoAGgmM0kPx1dB5OHf4WUQ1TKAuzAlUgaeG6Ars130_provenance.
- NP188288.RAprjns-iU9nlHTO4wFXiROTY27c88Ta-G6f_s5gUYy3g130_assertion description "[Defective assembly and trafficking of mutant HERG channels with C-terminal truncations in long QT syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188288.RAprjns-iU9nlHTO4wFXiROTY27c88Ta-G6f_s5gUYy3g130_provenance.
- NP188294.RAtxYpa9imkZZrguvXyecjru_o43SsUXPz5M2kghtuWx8130_assertion description "[Interestingly, crossing these AkitaKO mice with integrin α1KO mice, a model of exacerbated glomerulosclerosis after injury and also on the Balb/c background, resulted in a 16-fold increase in albuminuria, significant mesangial matrix expansion, nodular and diffuse glomerulosclerosis, and a 2-fold increase in glomerular basement membrane thickening when compared with nondiabetic mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188294.RAtxYpa9imkZZrguvXyecjru_o43SsUXPz5M2kghtuWx8130_provenance.
- NP188296.RAgwzgWXoEMiiz0gKcgZBiHseUMBCX6wLsouETochBlGs130_assertion description "[Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188296.RAgwzgWXoEMiiz0gKcgZBiHseUMBCX6wLsouETochBlGs130_provenance.
- NP188299.RAuO2YDfXrnQLAvhEFUN3bOqPWMfJ3V-5lpwCcvXG74XM130_assertion description "[This study therefore aims to clarify the relationship between single nucleotide polymorphisms (SNPs) in BDNF and a genetic predisposition to AR and asthma in an ethnic Chinese population of Singapore.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188299.RAuO2YDfXrnQLAvhEFUN3bOqPWMfJ3V-5lpwCcvXG74XM130_provenance.
- NP188301.RAnSjXGK5dV5EZl0Fah_d_fcbn2q1nVk4C1a7Q9SymIas130_assertion description "[Lack of association between the CALM1 core promoter polymorphism (-16C/T) and susceptibility to knee osteoarthritis in a Chinese Han population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188301.RAnSjXGK5dV5EZl0Fah_d_fcbn2q1nVk4C1a7Q9SymIas130_provenance.
- NP188303.RAgvqhryuFWDkDI5iN4KuOtNbhjz11vKGw-TpVeOVaUrs130_assertion description "[We assessed CA9 single nucleotide polymorphisms and mutations, and their association with CAIX protein expression, overall survival and response to interleukin-2 in white patients with metastatic clear cell renal cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188303.RAgvqhryuFWDkDI5iN4KuOtNbhjz11vKGw-TpVeOVaUrs130_provenance.
- NP188310.RAisANLMgoJXhRKb2qfRftGzBDrBmgCtZz1BBxmzuIDa4130_assertion description "[At presentation, the HCV-infected PBC group had significantly lower levels of ALP, gamma-glutamyl transpeptidase, and IgM than the AMA positive or AMA negative PBC patients (p < 0.01).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188310.RAisANLMgoJXhRKb2qfRftGzBDrBmgCtZz1BBxmzuIDa4130_provenance.
- NP188311.RAjhFL35dceHbu28PzofSRvxr3P_XXr9bFXNV-A8DXXfw130_assertion description "[Only 1 of 124 infiltrating lobular carcinomas (0.8%) showed HER2 overexpression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188311.RAjhFL35dceHbu28PzofSRvxr3P_XXr9bFXNV-A8DXXfw130_provenance.
- NP188313.RAt7EpBArfJQjO6yYbirIPGcaoBS-J-biXQKem3ENA1p8130_assertion description "[Our results implicate variation in FGF5 and ZNF652 gene upstream regions with altered susceptibility to hypertension in Han Chinese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188313.RAt7EpBArfJQjO6yYbirIPGcaoBS-J-biXQKem3ENA1p8130_provenance.
- NP188315.RAgyA2Pir_VKCq55x-kNxzCYrDod34jmZ3cMC8mwWV9yA130_assertion description "[Our aim is to analyze the expression of transcription repressors Snail, Slug, Twist, and SIP1 in SpCC of the head and neck in comparison to SCC, matched for location and stage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188315.RAgyA2Pir_VKCq55x-kNxzCYrDod34jmZ3cMC8mwWV9yA130_provenance.
- NP188318.RArnCLV6EXViguQ5QeBH4R2UL7XWPHK273KWODyBbTkO0130_assertion description "[Thus, our procedure identified at least one allelic variant of ATM associated with breast cancer, and indicated that the ATM locus may interact with HRAS1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188318.RArnCLV6EXViguQ5QeBH4R2UL7XWPHK273KWODyBbTkO0130_provenance.
- NP188321.RAoDz2i4cUala6rSga_8sS8KP3Ecesx6NtGiWGHFfn7c4130_assertion description "[Conversely, no association between GSTM1, GSTT1, and CYP2E1gene polymorphisms and coronary atherosclerosis was detected.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188321.RAoDz2i4cUala6rSga_8sS8KP3Ecesx6NtGiWGHFfn7c4130_provenance.
- NP188325.RAsJJzZCRubBtPkqzlmhITffLOls15GtR_1sWGSN2IaQ0130_assertion description "[Polymorphisms in the cytochrome P450 1B1 (CYP1B1) and glutathione S-transferase (GST) drug metabolic enzymes, which are responsible for metabolic activation/detoxification of estrogen and environmental carcinogens, were analyzed for their association with breast cancer risk in 541 cases and 635 controls from a North Carolina population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188325.RAsJJzZCRubBtPkqzlmhITffLOls15GtR_1sWGSN2IaQ0130_provenance.
- NP188327.RAlrq9MMOatqV1jep14C2o5lK9ZjsqHnKmlIOt1fOrJPY130_assertion description "[In self-identified white patients with major depressive disorder (N=126) treated with open-label duloxetine (60-120 mg/d), a significant association of (P=0.020) of a composite risk score (based on SLC6A2 rs5569 [G1287A] AA, HTR1A rs6295 [C(-1019)G] GG, and COMT rs174697 AA/AG) with 17-item Hamilton Depression Rating Scale total score change from baseline to 12 weeks was observed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188327.RAlrq9MMOatqV1jep14C2o5lK9ZjsqHnKmlIOt1fOrJPY130_provenance.
- NP188328.RAn9QeNvzUAVtlcxwKtzMtF413qdQXbs3hsk0j2uPySgo130_assertion description "[A significant association between anti-VacA antibodies and diffuse GC was found using neutralization [odds ratio (OR)=1.69, 95 % CI 1.08-2.66], but the association did not remain significant after adjusting for CagA status (OR 1.37, 95 % CI 0.81-2.32).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188328.RAn9QeNvzUAVtlcxwKtzMtF413qdQXbs3hsk0j2uPySgo130_provenance.
- NP188333.RArILcwEB6VuP1T_URQiHIkjNu7T7_HCUe5nDfqykmvZI130_assertion description "[Interleukin (IL)-23, IL-17A, IL-17F, and interferon-gamma (IFN-γ) are important mediators of inflammatory colitis and are potential therapeutic targets in inflammatory bowel disease (IBD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188333.RArILcwEB6VuP1T_URQiHIkjNu7T7_HCUe5nDfqykmvZI130_provenance.
- NP188335.RArOLqWPodDVHjzTWtCsN2uNXN7Nk_6pobyyPDg3De7MM130_assertion description "[We report a case of Wolf-Hirschhorn syndrome in a female infant with a 4p deletion, for which the breakpoint was detected at p14.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188335.RArOLqWPodDVHjzTWtCsN2uNXN7Nk_6pobyyPDg3De7MM130_provenance.
- NP188344.RAmbgiwjBjBNPksOwFaF4a6XsrjdevakHHgcvWOzzqk0E130_assertion description "[These results suggest that VASP protein regulates osteosarcoma cell migration and metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188344.RAmbgiwjBjBNPksOwFaF4a6XsrjdevakHHgcvWOzzqk0E130_provenance.
- NP188345.RAmCUVKO82VZ3HY8bc0wRyAlRsUD1keJlYSqOuyGjlL00130_assertion description "[The interaction of SCC with fibroblasts, possibly occurring during the invasive phase of SCC, may be the stimulus for enhanced PLP production, thus contributing to the genesis of humoral hypercalcemia of malignancy in this type of cancer (Cancer Res 50:3589-3594, 1990).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188345.RAmCUVKO82VZ3HY8bc0wRyAlRsUD1keJlYSqOuyGjlL00130_provenance.
- NP188351.RAljNvkvJCtsRQV74DW435sZ6A2xDPLJQiu7clhpUAbjc130_assertion description "[In colorectal and gastric cancers, the use of epidermal growth factor receptor inhibitors and HER2/neu inhibitors has increased the available treatment options for patients with advanced disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188351.RAljNvkvJCtsRQV74DW435sZ6A2xDPLJQiu7clhpUAbjc130_provenance.
- NP188352.RApS3lQe2_zR1kMJozMJhx3ZMXy6-L-j-1qzz1qSKr3MQ130_assertion description "[A novel 28-bp deletion in the RPGR gene identified in an X-linked Chinese RP family causes severe RP in male patients as well as myopia and ERG abnormalities in female carriers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188352.RApS3lQe2_zR1kMJozMJhx3ZMXy6-L-j-1qzz1qSKr3MQ130_provenance.
- NP188360.RArKC-LJCOrrcWE_W66syY_VeeKOeou8tF5QViut34u80130_assertion description "[Small molecule kinase inhibitors of EGFR and of both HER2 and EGFR have received approval for the treatment of cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188360.RArKC-LJCOrrcWE_W66syY_VeeKOeou8tF5QViut34u80130_provenance.
- NP188362.RAp1rintbedFeFIJ7-GNOzBfx6CtFY_JzTTBy6EQXsJjE130_assertion description "[With the goal of identifying a potential intermediate biomarker in the multistep process of head and neck cancer development, we conducted immunohistochemical analyses for p53 expression in 33 patients with head and neck squamous cell carcinomas whose tissue sections contained adjacent normal epithelium, hyperplastic, and/or dysplastic lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188362.RAp1rintbedFeFIJ7-GNOzBfx6CtFY_JzTTBy6EQXsJjE130_provenance.
- NP188366.RAsczHQSJUWaPpjTMc0AHHTyi5XQI8H2r5Vo8hQ-q2uho130_assertion description "[In the present study, we have investigated a series of 37 meningiomas for mutation and expression of 4 tumor suppressor genes (MADH2, MADH4, APM-1 and DCC) located at 18q21.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188366.RAsczHQSJUWaPpjTMc0AHHTyi5XQI8H2r5Vo8hQ-q2uho130_provenance.
- NP188370.RAjZELo7IA70opMoBtelSOtRQntHcZF0dEc_5BL9-m6kg130_assertion description "[The serum positivity and mean absorbance value of HP-NAP-specific antibodies in the gastric cancer group (97.7% and 1.01 +/- 0.24) were significantly higher than those in the chronic gastritis group (85.7% and 0.89 +/- 0.14, P < 0.005) and healthy control group (27.7% and 0.65 +/- 0.18, P < 0.001).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188370.RAjZELo7IA70opMoBtelSOtRQntHcZF0dEc_5BL9-m6kg130_provenance.
- NP188371.RApX2kqiWms-EHCtS1kAGaVfix6wFxhMaHvOUEg-BO14U130_assertion description "[These results suggest that the IRS-1 genetic polymorphism is involved in the occurrence of gestational diabetes, as well as type 2 diabetes mellitus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188371.RApX2kqiWms-EHCtS1kAGaVfix6wFxhMaHvOUEg-BO14U130_provenance.
- NP188379.RAhN-HAgC3Gv_TBFXL07kMjuwYZ8ARB6HMaoKnc3WSvug130_assertion description "[A significant association (OR = 2.70) between short rare MUC6-MS5 alleles (7, 9 repeats) and the occurrence of cancer was observed in rectal cancer [95 % confidence interval (CI), 1.12-6.54; p = 0.022].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188379.RAhN-HAgC3Gv_TBFXL07kMjuwYZ8ARB6HMaoKnc3WSvug130_provenance.
- NP188384.RAhbcWkHlztmjcJyO_5Ge75hOKt6kmD5zLv0h-SxgY7S4130_assertion description "[An early step in the carcinogenesis of hereditary non-polyposis colorectal cancer (HNPCC) and some sporadic colorectal cancers (CRCs) is the acquisition of a 'mutator phenotype' resulting from defects in DNA mismatch repair (MMR) genes, which normally maintain genomic stability.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188384.RAhbcWkHlztmjcJyO_5Ge75hOKt6kmD5zLv0h-SxgY7S4130_provenance.
- NP188385.RApLylyrXg6L7Izhbm1KzIoH17oIUwojaFruY4AOwVUDk130_assertion description "[Levels of both TGF beta 1 and TGF beta 3 increased with increasing cell density for leiomyoma and myometrium smooth muscle cells cultured in vitro.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188385.RApLylyrXg6L7Izhbm1KzIoH17oIUwojaFruY4AOwVUDk130_provenance.
- NP188387.RAvfbtGdDGTlm46Keg9EE7e2SVWMg6M3q2qoBpBC5DE90130_assertion description "[In a patient with CGL and insulin resistance we investigated the known candidate genes but the patient did not carry a relevant mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188387.RAvfbtGdDGTlm46Keg9EE7e2SVWMg6M3q2qoBpBC5DE90130_provenance.
- NP188391.RAncWxXiHqgXCDGhjDiQcqhT_oM7a20X7fZnwgPz488xY130_assertion description "[In another study (Abstract #147), substantial responses were observed in both patients with BRCA2-associated pancreatic cancer treated with the poly-(ADP-ribose) polymerase (PARP) inhibitor ABT-888 (veliparib).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188391.RAncWxXiHqgXCDGhjDiQcqhT_oM7a20X7fZnwgPz488xY130_provenance.
- NP188394.RAgjDn5LnyISaRR456zELHfo-0RAscYe3hopyBE0-ctnA130_assertion description "[We carried out an association study of BD with CREB1, CREB2 and CREB3 genes, located at ch 2q32.3-q34, 22q13.1 and 9pter-p22.1, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188394.RAgjDn5LnyISaRR456zELHfo-0RAscYe3hopyBE0-ctnA130_provenance.
- NP188395.RAg2R7Y1w-PrsgTbZfHvctQ8qJfYOHNtmKomOAQpHdlso130_assertion description "[Current data implicating the role of human papillomavirus (HPV) infections in squamous cell carcinogenesis may be summarised as follows: animal models have shown that PVs can induce malignant transformation; HPV involvement in both benign and malignant human squamous cell tumours has been demonstrated by morphological, immunohistochemical and DNA hybridisation techniques; HPV infections in the genital tract are venereally transmitted and are associated with the same risk factors as cervical carcinoma; the natural history of cervical HPV lesions is similar to that of CIN, namely, they have the potential to develop into carcinoma in situ; malignant transformation of PV-induced lesions seems to depend on virus type and the physical state of its DNA, e.g., whether or not it is integrated in the host cell DNA; malignant transformation most probably requires synergistic actions between the PVs and chemical or physical carcinogens, or other infectious agents; genetic disposition (at least in animals) significantly contributes to malignant transformation; immunological defence mechanisms of the host are probably capable of modifying the course of PV infections (efficacy in man remains to be elucidated).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188395.RAg2R7Y1w-PrsgTbZfHvctQ8qJfYOHNtmKomOAQpHdlso130_provenance.
- NP188396.RApXGalSJ7_q9g0FPYOTGp1r22yDG-grHD3rpL-EI33Q8130_assertion description "[We also analyzed the effect of inflammatory modulators like TNF-α, lipopolysaccharides (LPS) and drugs (5-ASA, prednisolone and hydrocortisone) on the expression of ABCA1, ABCB8, ABCF2 and ABCC4 using HT-29 cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188396.RApXGalSJ7_q9g0FPYOTGp1r22yDG-grHD3rpL-EI33Q8130_provenance.
- NP188399.RAtszbo3gPEnF-mfpd14OdfJtVDNzDnprQ6OwSBRAUkWc130_assertion description "[The multivariate logistic regression showed that HPV viral load was associated with an increased odds of LSIL/HSIL, odds ratio of 10.7 (95% CI 2.0 - 57.7) for those that were HC2 positive and had a viral load of <or= 181.1 RLU (the median HPV viral load), and 33.8 (95% CI 6.4 - 178.9) for those that were HC2 positive with a HPV viral load > 181.1 RLU.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188399.RAtszbo3gPEnF-mfpd14OdfJtVDNzDnprQ6OwSBRAUkWc130_provenance.
- NP188402.RAufFvpVQpK7Sy6aa2Y7GIbduURbUZNUcEpRVXxDRDuG4130_assertion description "[Interestingly, male patients with EGF G/G had a 1.6-fold higher risk of recurrence (HR 1.6; 95% CI 1.0-2.5, P = 0.07).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188402.RAufFvpVQpK7Sy6aa2Y7GIbduURbUZNUcEpRVXxDRDuG4130_provenance.
- NP188403.RAuKECjfIi1ia6BJZSg4r-H7BVontwRqdA83BGPjfLBjA130_assertion description "[Considering the need to treat advanced TC more effectively, disparate findings in predictive molecular markers (eg, KIT mutations in TSCC, but not in thymomas) suggest that targeted treatments will have to be different in thymomas and TC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188403.RAuKECjfIi1ia6BJZSg4r-H7BVontwRqdA83BGPjfLBjA130_provenance.
- NP188405.RAuVEdOP6dhhiQsvYtJb7eYkXHIVBdHAGBEFGllnZp0uE130_assertion description "[Methylation of the p73 gene in gliomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP188405.RAuVEdOP6dhhiQsvYtJb7eYkXHIVBdHAGBEFGllnZp0uE130_provenance.