Nanopublications

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NP216420.RAmXsgi1cEYrRDP183A9-LKbNd46dImVPdDhXF4x-hN7Q130_assertion description "[The steroid receptor coactivator-3 (SRC-3), also known as p/CIP, RAC3, AIB1, ACTR and TRAM-1, is a cancer-amplified coactivator in the SRC gene family that also contains SRC-1 and TIF2/GRIP1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216420.RAmXsgi1cEYrRDP183A9-LKbNd46dImVPdDhXF4x-hN7Q130_provenance.
NP216421.RAnLt7_5R85Zxj2J7cdKqc0nj1W-KP2a12jwo4JJggM24130_assertion description "[Because the DISC1 gene is shown to be a causative gene for psychosis in a Scottish family, the FEZ1 gene may well have importance in mental disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216421.RAnLt7_5R85Zxj2J7cdKqc0nj1W-KP2a12jwo4JJggM24130_provenance.
NP216424.RAsmHJcGGZl1SM5jtmi_DMW6YxEzD6pU2nnSygpBn9r9w130_assertion description "[A reduction in immunohistochemically detectable ATM protein in sporadic breast carcinoma implicates ATM in the progression of the disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216424.RAsmHJcGGZl1SM5jtmi_DMW6YxEzD6pU2nnSygpBn9r9w130_provenance.
NP216426.RAt0KatiJnmmYq1RXNFo1dlplpXzmnaFcQ-ZQya27Mg_I130_assertion description "[Compound heterozygous mutations in the GNAS gene of a boy with morbid obesity, thyroid-stimulating hormone resistance, pseudohypoparathyroidism, and a prothrombotic state.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216426.RAt0KatiJnmmYq1RXNFo1dlplpXzmnaFcQ-ZQya27Mg_I130_provenance.
NP216428.RAgb39LtT8D_kwYoa4mIxXesUtwsWWv6s9iRHs0pMlb_0130_assertion description "[Thirty-eight malignant mesothelioma (MM) specimens were subjected to IHC staining and FISH to evaluate the expression of EGFR protein and gene status.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216428.RAgb39LtT8D_kwYoa4mIxXesUtwsWWv6s9iRHs0pMlb_0130_provenance.
NP216430.RAl-pXmi7xmeUPtepAed1P-YQ23owsu10TkACsh45ADEE130_assertion description "[Strikingly, profiling of the T-ALLs by clinical, genomic, and large-scale gene expression analyses shows that the TCRB-MYB translocation defines a new T-ALL subtype associated with a very young age for T-cell leukemia (median, 2.2 years) and with a proliferation/mitosis expression signature.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216430.RAl-pXmi7xmeUPtepAed1P-YQ23owsu10TkACsh45ADEE130_provenance.
NP216431.RAsyBr73Aeg2B-WWIZ78ERTnBY51Y0rPamOhv3jGDbvsg130_assertion description "[The PD1/PDL1 pathway is an important element contributing to tumor-mediated immune suppression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216431.RAsyBr73Aeg2B-WWIZ78ERTnBY51Y0rPamOhv3jGDbvsg130_provenance.
NP216433.RAnCaamUTNuAd9QSrhLav8_iMmSKzhdHq6oAQ-UUUZx8A130_assertion description "[The results showed that, KLK10 was significantly downregulated in NSCLC (57.7%, 45/78) as compared to non-cancer samples (P = 0.010).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216433.RAnCaamUTNuAd9QSrhLav8_iMmSKzhdHq6oAQ-UUUZx8A130_provenance.
NP216437.RAvWIzYctnw_3b9Sh36Y4QnyBjhPXzndCvj2y5-jxiqMs130_assertion description "[To identify genetic changes that cooperate with PML-RARA in leukemogenesis, we performed spectral karyotyping analysis of myeloid leukemias from hMRP8-PML-RARA mice (11 cases) and from mice coexpressing PML-RARA and BCL2 (8 cases).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216437.RAvWIzYctnw_3b9Sh36Y4QnyBjhPXzndCvj2y5-jxiqMs130_provenance.
NP216442.RAsIM2ns_aaTT8-S5G8IagZFhCwh2PFg5eLHtNE6VamJc130_assertion description "[To analyze the promoter region of PIP5K2A, a phosphatidylinositol 4-phosphate 5-kinase that maps to 10p in a region linked to both bipolar disorder and schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216442.RAsIM2ns_aaTT8-S5G8IagZFhCwh2PFg5eLHtNE6VamJc130_provenance.
NP216451.RAnGcmqliuaDbHIh5WeygVDP57FPsCzpYHYHWknyNrEjA130_assertion description "[However, p53 overexpression or mutation and decreased expression of p27 are associated with cancer progression and survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216451.RAnGcmqliuaDbHIh5WeygVDP57FPsCzpYHYHWknyNrEjA130_provenance.
NP216464.RAts5jaLzMinSs1A6cAOAStyqox6SxaAM_3DOURc2FMQE130_assertion description "[In this study, we demonstrated that GITR is inactivated during tumor progression in Multiple Myeloma (MM) through promoter CpG island methylation, mediating gene silencing in primary MM plasma cells and MM cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216464.RAts5jaLzMinSs1A6cAOAStyqox6SxaAM_3DOURc2FMQE130_provenance.
NP216469.RAsB-s8zrkg-l6XdD4k5TpbJPmGBCYFE-saEUp8ClkrmI130_assertion description "[Diamond-Blackfan anemia (DBA) is a rare congenital pure red cell hypoplasia characterized by a selective defect of erythropoiesis with a normochromic macrocytic anemia and reticulocytopenia often accompanied by various congenital anomalies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216469.RAsB-s8zrkg-l6XdD4k5TpbJPmGBCYFE-saEUp8ClkrmI130_provenance.
NP216483.RAu7R89bVp0EIfCqoSjmuLPmxnjs9gkiXB8tCHBg4991M130_assertion description "[We compared the density of neurofibrillary tangles (NT) and neuritic (senile) plaques (NP) in 10 cortical areas, the amygdala, the hippocampus, the parahippocampal gyrus, and the cerebellum in patients with familial (FAD) and sporadic (SAD) Alzheimer's disease with early (< 55 years), intermediate (55-70 years) and late (> 70 years) ages of onset of dementia and age-matched controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216483.RAu7R89bVp0EIfCqoSjmuLPmxnjs9gkiXB8tCHBg4991M130_provenance.
NP216484.RAhx-A5SzMudi8QhfLL2D22ZlTo_jpoeeVC1nKFL5YXNc130_assertion description "[Expression of sFRP2 was examined in 20 pairs of primary cancers by immunohistochemistry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216484.RAhx-A5SzMudi8QhfLL2D22ZlTo_jpoeeVC1nKFL5YXNc130_provenance.
NP216487.RAhzNrP1gcwqp61JHtktJYGGuuQlNyOOOfup5SYQ1NrQA130_assertion description "[Germline mutations in the base excision repair gene, MutY human homolog (MYH), have recently been associated with a recessively inherited multiple adenoma polyposis syndrome and colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216487.RAhzNrP1gcwqp61JHtktJYGGuuQlNyOOOfup5SYQ1NrQA130_provenance.
NP216493.RApkXjOUw24SlgHkshmY3Va1Bsyc0G3x3Ra8DXggU_Z_E130_assertion description "[Although ischemic stroke can result from merely one gene defect (and a number of clearly defined mendelian hereditary disorders do lead to stroke), the interaction of unfavorable genetic factors such as the Leiden V, methylenetetrahydrofolate reductase (MTHFR) 677TT, apolipoprotein E (ApoE) 4, and angiotensin-converting enzyme (ACE) D/D genotypes, which alone are not major risk factors, can in specific patterns exert a synergistic effect on certain clinical risk factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216493.RApkXjOUw24SlgHkshmY3Va1Bsyc0G3x3Ra8DXggU_Z_E130_provenance.
NP216507.RAhDh3Jr8E5mhuIMU56HpnsY72rn3Xo2o4IwUpcTU0vmY130_assertion description "[Three different exostosis (EXT) loci on chromosomes 8q (exostosin 1, EXT1), 11p (exostosin 2, EXT2) and 19p (exostosin 3, EXT3) have been reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216507.RAhDh3Jr8E5mhuIMU56HpnsY72rn3Xo2o4IwUpcTU0vmY130_provenance.
NP216513.RAh2Agt-Cc8tGfXjoZYLjEfZOeUMjrBLBFMoJIx6sw54Y130_assertion description "[Intratumoral injection of Ad5CMV-p53 is safe, feasible and biologically active when administered in multiple doses to patients with esophageal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216513.RAh2Agt-Cc8tGfXjoZYLjEfZOeUMjrBLBFMoJIx6sw54Y130_provenance.
NP216522.RApUQU6hn1eLbQ404w5HjlCAG45iJPq_Sdy4rS0LGV7_c130_assertion description "[The androgen receptor (AR) and enzymes (AKR1C3, HSD17B2, HSD17B3, UGT2B15 and UGT2B17 ) that are involved in the metabolism of adrenal steroids were upregulated in castration resistant prostate cancer (CRPC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216522.RApUQU6hn1eLbQ404w5HjlCAG45iJPq_Sdy4rS0LGV7_c130_provenance.
NP216527.RAhi5SuamHbDjyy4Ol-1OHaOvrycYokxiGvcfeJ4NAoic130_assertion description "[To investigate the potential consequences of somatic heterozygosity for a BRCA1 mutation demonstrably associated with breast carcinogenesis on background somatic mutational burden, we applied the two standard assays of in vivo human somatic mutation to blood samples from a manifesting carrier of the Q1200X mutation in BRCA1 whose tumor was uniquely ascertained through an MRI screening study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216527.RAhi5SuamHbDjyy4Ol-1OHaOvrycYokxiGvcfeJ4NAoic130_provenance.
NP216530.RAtsj-GulD7dldDL9kPqIVN3Ws9D4bNYQ92Tvk30sslMA130_assertion description "[The presence of MHC class I antigens and TAP-1 was studied in a series of 93 resection specimens of non-small-cell lung carcinomas (NSCLCs) by immunohistochemical methods using antibodies against the assembled class I molecule, beta 2-microglobulin (beta 2-m), heavy-chain A locus, A2 allele and TAP-1 protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216530.RAtsj-GulD7dldDL9kPqIVN3Ws9D4bNYQ92Tvk30sslMA130_provenance.
NP216531.RAimsf3Mddzn0na-zc1LLiUEvNVfurJ-acvX7qW9Oc3BQ130_assertion description "[Genetic polymorphisms of the renin-angiotensin system have been reported to be related to the clinical outcomes in immunoglobulin A nephropathy (IgAN).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216531.RAimsf3Mddzn0na-zc1LLiUEvNVfurJ-acvX7qW9Oc3BQ130_provenance.
NP216532.RArSnIA1uFMOpjrDbSSYOk6HaJGYR0ScnD46AVyZQrUxM130_assertion description "[We present Classification by Ensembles from Random Partitions (CERP) for class prediction and apply CERP to genomic data on leukemia patients and to genomic data with several clinical variables on breast cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216532.RArSnIA1uFMOpjrDbSSYOk6HaJGYR0ScnD46AVyZQrUxM130_provenance.
NP216535.RAgMpzCMM45gGJG4_w9yt2ozqNRJGjOgJzAiGjrUS7Slw130_assertion description "[PTPN22 (1p13.2), STAT4 (2q32.2), CTLA4 (2q33.2), HLA (6p21), IL2RA (10p15.1), INS (11p15.5), ERBB3 (12q13.2), SH2B3 (12q24.12), and CLEC16A (16p13.13) were convincingly associated with autoimmune diabetes in adults (P ≤ 0.002), with consistent directions of effect as reported for pediatric type 1 diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216535.RAgMpzCMM45gGJG4_w9yt2ozqNRJGjOgJzAiGjrUS7Slw130_provenance.
NP216538.RAmHe_6kaq8DYKuBKTg8jSlVssGhF-HOZV1eBitN-S1Zk130_assertion description "[Hence, UBQLN2 was not found to be a cause of familial ALS in the Netherlands.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216538.RAmHe_6kaq8DYKuBKTg8jSlVssGhF-HOZV1eBitN-S1Zk130_provenance.
NP216540.RAtOv0XfuwZQ0w8t2JSdN5KVCUl460xtSdrmZiO-n4L60130_assertion description "[The present study shows that the neural phenotype of Ewing's tumors is attributable to the EWS-FLI1 expression and the resultant phenotype resembles developing neural crest.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216540.RAtOv0XfuwZQ0w8t2JSdN5KVCUl460xtSdrmZiO-n4L60130_provenance.
NP216542.RAgICYJBoT2g0c3drgHZ7v3AOQtGJ17jQMj5MM_-wdV_c130_assertion description "[We performed a study to assess clinical significance, especially prognostic impact, of MUC1 expression in NSCLC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216542.RAgICYJBoT2g0c3drgHZ7v3AOQtGJ17jQMj5MM_-wdV_c130_provenance.
NP216543.RApKVem_h7azdTVziLuwti52bgL5E_l893XrjexWBxzAw130_assertion description "[WT1 expression at diagnosis does not predict survival in pediatric AML: a report from the Children's Oncology Group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216543.RApKVem_h7azdTVziLuwti52bgL5E_l893XrjexWBxzAw130_provenance.
NP216551.RAmbKFt2Dy3dYU2ByZUd4GM9v-tAUOhAfhTgvbzXTHVJs130_assertion description "[Herein are illustrated some pitfalls in the diagnosis of melanoma, as well as variants of Spitz's nevus that correlate with specific genomic aberrations such as gains of chromosome 11p and loss of the BAP-1 gene on chromosome 3p.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216551.RAmbKFt2Dy3dYU2ByZUd4GM9v-tAUOhAfhTgvbzXTHVJs130_provenance.
NP216558.RAnV2QOeKSWYM5ZvutygQ4PHPCE_hORHSxy9coIdf_wU4130_assertion description "[We examined 43 sporadic bone and soft-tissue sarcomas for molecular genetic alterations affecting the retinoblastoma susceptibility gene Rb-1 (also known as RB1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216558.RAnV2QOeKSWYM5ZvutygQ4PHPCE_hORHSxy9coIdf_wU4130_provenance.
NP216562.RAqjlPNSDnxbqsk4cB4sx4axiWX2vKq0_0iBUAx9Hc-yU130_assertion description "[The COMT Met158 allele and violence in schizophrenia: a meta-analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216562.RAqjlPNSDnxbqsk4cB4sx4axiWX2vKq0_0iBUAx9Hc-yU130_provenance.
NP216563.RAlX3qEw0VKxA4OLinDUDNde4R5DfN_Fx3womznw3awzs130_assertion description "[Targeted therapy against the BRAF/mitogen-activated protein kinase (MAPK) pathway is a promising new therapeutic approach for the treatment of melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216563.RAlX3qEw0VKxA4OLinDUDNde4R5DfN_Fx3womznw3awzs130_provenance.
NP216564.RApagilevqr8bdXIkrgItezSPelb4aY-WURgOyqwtKIYY130_assertion description "[We tested the reliability of MLPA by analyzing DNA isolated from formalin-fixed melanomas that were previously characterized by comparative genomic hybridization (CGH), and additionally the applicability of MLPA was tested by analyzing 29 routinely processed melanocytic lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216564.RApagilevqr8bdXIkrgItezSPelb4aY-WURgOyqwtKIYY130_provenance.
NP216568.RAodBmjxGY9e0wHGp19OHWjMBrpfVhDBr75uwQ0kYRU-U130_assertion description "[Mutations in the AR gene can be associated with isolated micropenis without other features of PAIS, such as hypospadias or gynecomastia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216568.RAodBmjxGY9e0wHGp19OHWjMBrpfVhDBr75uwQ0kYRU-U130_provenance.
NP216571.RAuJltQxAlShtRHGegxTngISU2YFnI0GpdrTdxajxq8Xk130_assertion description "[Moreover, the relative risks associated with the 1S/S genotype for patients with LADA showed a substantial increase with respect to those with type 1 diabetes (52%) when we compare them to the controls (1S/S LADA/control, 2.282 [RR1] vs type 1 diabetes/control, 1.497 [RR2]).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216571.RAuJltQxAlShtRHGegxTngISU2YFnI0GpdrTdxajxq8Xk130_provenance.
NP216578.RAl9WmnhnPPjYFhhjpQSP97OSl4MvGXgUwRacm0AZ-umU130_assertion description "[Evaluation of genotype distributions by the chi2-test and subsequent multivariable logistic regression analysis with adjustment for covariates revealed that the 3949T-->G (3' untranslated region) polymorphism of the thrombospondin-2 gene (THBS2; odds ratio, 4.6), the -110A-->C polymorphism of the heat shock 70-kDa protein 8 gene (HSPA8; odds ratio, 0.4), the C-->T (Pro198Leu) polymorphism of the glutathione peroxidase 1 gene (GPX1; odds ratio, 0.3), the -6G-->A polymorphism of the angiotensinogen gene (AGT; odds ratio, 0.3), and the -850C-->T polymorphism of the tumor necrosis factor gene (TNF; odds ratio, 0.5) were significantly (P < 0.05) associated with TAA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216578.RAl9WmnhnPPjYFhhjpQSP97OSl4MvGXgUwRacm0AZ-umU130_provenance.
NP216580.RAnvkurREo9mtdmmEhNRQn0b6fQU1Kdn3oYO-hsThqto4130_assertion description "[In order to test this hypothesis, we genotyped the 941T > G and the promoter VNTR polymorphisms in the MAOA gene and the Val 108/158 Met COMT polymorphism in 305 families with at least one member having bipolar disorder (BD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216580.RAnvkurREo9mtdmmEhNRQn0b6fQU1Kdn3oYO-hsThqto4130_provenance.
NP216590.RArBPirVofuF3Kc7NkNItu8umma_1LOtEkyPJOMiVr95U130_assertion description "[In multivariate analysis, when considering karyotype, transfusion dependence, and IDH1 mutation status, ASXL1 frameshift mutations remained an independent prognostic marker in MDS (overall survival: HR, 1.85; 95% CI, 1.03 to 3.34; P = .040; time to AML progression: HR, 2.39; 95% CI, 1.12 to 5.09; P = .024).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216590.RArBPirVofuF3Kc7NkNItu8umma_1LOtEkyPJOMiVr95U130_provenance.
NP216593.RAppQUe0feSc-uHkpjufK5_Q9tdhjyoG_JagQ-yDmoZWs130_assertion description "[Most patients with NR5A1 (SF-1) mutations and poor virilization at birth are sex-assigned female and receive early gonadectomy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216593.RAppQUe0feSc-uHkpjufK5_Q9tdhjyoG_JagQ-yDmoZWs130_provenance.
NP216595.RArs3Wa0kfXRDUz6QXVpnDiCE9JhYMHhLCP7Mot5G1478130_assertion description "[In this article, we report that POU5F1 was fused to EWSR1 in a case of undifferentiated sarcoma derived from pelvic bone with chromosomal translocation t(6;22)(p21;q12).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216595.RArs3Wa0kfXRDUz6QXVpnDiCE9JhYMHhLCP7Mot5G1478130_provenance.
NP216599.RAiKV8cdLgPKxoskk9bjVGkzA6NWsKrDokSbP1dey9ZWc130_assertion description "[We concluded that IL-20 may be involved in the injury of renal epithelial cells in acute renal failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216599.RAiKV8cdLgPKxoskk9bjVGkzA6NWsKrDokSbP1dey9ZWc130_provenance.
NP216610.RAqgFsNdXzTb5hn1UCo6R9kg3CmZ140vf5pcN30kPIDOk130_assertion description "[Thus interactive effects related to HLA-DR2/DR4 and DR4/DR5 may predispose to pernicious anaemia without endocrine disease, whereas interactive effects related to HLA-DR3/DR4 may predispose to pernicious anaemia in association with endocrine disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216610.RAqgFsNdXzTb5hn1UCo6R9kg3CmZ140vf5pcN30kPIDOk130_provenance.
NP216611.RAhyxstYMd2CC6mUGL9SCXZ65IqMzvHCyiEOMGcL9bGYU130_assertion description "[Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC): evidence for trans-allele repression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216611.RAhyxstYMd2CC6mUGL9SCXZ65IqMzvHCyiEOMGcL9bGYU130_provenance.
NP216615.RAvR87HUo5CyZl8L1vZhVJaxe8F68Z7SfhdL8EsBf9u5Y130_assertion description "[Our findings indicate that common SNPs in the MDR1 gene are associated with an overall susceptibility for UC and specific disease phenotypes in North Indians.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216615.RAvR87HUo5CyZl8L1vZhVJaxe8F68Z7SfhdL8EsBf9u5Y130_provenance.
NP216617.RAsFzDKSMZbC2sSdghnGmMweKwF0Jp1wgbmpgtN34aOgs130_assertion description "[Acquired causes include conditions such as surgery, cancer, and prolonged immobilization, while genetic causes have been linked to the inherited deficiencies of antithrombin, protein C, and protein S. The identification of the genetic basis of these inherited causes of thrombophilia ushered in a new way of thinking about thrombosis and the importance of its genetic component.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216617.RAsFzDKSMZbC2sSdghnGmMweKwF0Jp1wgbmpgtN34aOgs130_provenance.
NP216618.RAvv8EyH_V5r_eMH59B0-apwBapigUI_jhWcalqzkjPNc130_assertion description "[Since majority of prostate tumors express wild-type p53, its activation by MDM2 antagonists in combination with androgen depletion may offer an efficacious new approach to prostate cancer therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216618.RAvv8EyH_V5r_eMH59B0-apwBapigUI_jhWcalqzkjPNc130_provenance.
NP216619.RAowdMzQmHQp6hdpG8T3KTBECWXdn-oPs2v4ixdmbPGzA130_assertion description "[Finally, the stronger association at S mu rather than at the downstream S alpha 1, Gm and D14S1 loci suggest that the genes predisposing to MG are located within the variable region of the Ig heavy chain loci.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216619.RAowdMzQmHQp6hdpG8T3KTBECWXdn-oPs2v4ixdmbPGzA130_provenance.
NP216628.RAq7x1iPkRmstGPPu-pXMaWsbG1XibpUNvaqS9iOnpzEc130_assertion description "[In conclusion, this meta-analysis suggests that the LSP1 rs3817198T>C polymorphism is a low-penetrant risk factor for developing breast cancer but may not be in Africans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216628.RAq7x1iPkRmstGPPu-pXMaWsbG1XibpUNvaqS9iOnpzEc130_provenance.
NP216634.RAqcBOeshof4l2d8inLVvxOAggzLbTIl7SGwq7RbW1cUs130_assertion description "[No BRAF mutations were detected in 33 HNPCC colorectal carcinomas, while they were detected in 3 of 26 (12%) FAP carcinomas and 2 of 53 (4%) microsatellite stable sporadic carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216634.RAqcBOeshof4l2d8inLVvxOAggzLbTIl7SGwq7RbW1cUs130_provenance.
NP216639.RAmdRzlUDdbwvzuB_Xo1e1rq-b_PWHacmW_OddvMzCDoQ130_assertion description "[Retrovirus-mediated sFlt-1 gene modification was performed to examine the influence of VEGF in controlling the growth of an experimental osteosarcoma in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216639.RAmdRzlUDdbwvzuB_Xo1e1rq-b_PWHacmW_OddvMzCDoQ130_provenance.
NP216643.RAm_1xm5Sy_Y1d2i0GEIJKRXqAYga-P6-eGVZcqpN_OPQ130_assertion description "[Bloom's syndrome (BS) is a rare recessive disorder caused by germline mutation of the BLM gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216643.RAm_1xm5Sy_Y1d2i0GEIJKRXqAYga-P6-eGVZcqpN_OPQ130_provenance.
NP216652.RAtHtwzh3d0ssK7wMdU_7PZu_o2gpfjJthJaMGdw4Ceow130_assertion description "[The present study evaluated single-nucleotide polymorphisms (SNPs) in XRCC3, XPD and Aurora kinase A in NSCLC patients in order to assess whether these biomarkers were able to predict the outcomes of the patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216652.RAtHtwzh3d0ssK7wMdU_7PZu_o2gpfjJthJaMGdw4Ceow130_provenance.
NP216661.RAu1TmlmTyJ2PIkyL-dDLmPj5d_U-_Jx5b7hL2PbaF_Gg130_assertion description "[Triggering of antitumor activity through melanoma-specific transduction of a constitutively active tumor necrosis factor (TNF) R1 chimeric receptor in the absence of TNF-alpha.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216661.RAu1TmlmTyJ2PIkyL-dDLmPj5d_U-_Jx5b7hL2PbaF_Gg130_provenance.
NP216663.RAiDgRYUlCpmK5IugAqR5gbc4AkBKHAYY_EYx58jk9JUM130_assertion description "[We review here the current understanding of PCSK9 and its potential as a therapeutic target through which to reduce LDL cholesterol for prevention and treatment of coronary heart disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216663.RAiDgRYUlCpmK5IugAqR5gbc4AkBKHAYY_EYx58jk9JUM130_provenance.
NP216666.RAoU2ZX5Wz01yQ56p3CJuC6cJsOqIaZ1URyfDTdETZSG8130_assertion description "[The phosphatase activity associated with R3E is slightly higher than that associated with R5/PTG and it is downregulated in streptozotocin-induced diabetes by 60-70% and restored by insulin treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216666.RAoU2ZX5Wz01yQ56p3CJuC6cJsOqIaZ1URyfDTdETZSG8130_provenance.
NP216671.RAhY_nzVS1UYvqneihTqBo_XCmPNXawV92vkK9RfHuERs130_assertion description "[Recently, the novel antifolates raltitrexed and pemetrexed that target thymidylate synthase (TS) and glycineamide ribonucleotide transformylase (GARTF) were introduced for the treatment of colorectal cancer and malignant pleural mesothelioma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216671.RAhY_nzVS1UYvqneihTqBo_XCmPNXawV92vkK9RfHuERs130_provenance.
NP216683.RAt0PvJKheYbxDl6z34ffFjk9pfL3IANhVOoa15SlaHJc130_assertion description "[High levels of circulating IGF1 and certain genetic polymorphisms of IGF1 and IGFBP3 are associated with an increased risk of several common cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216683.RAt0PvJKheYbxDl6z34ffFjk9pfL3IANhVOoa15SlaHJc130_provenance.
NP216688.RAscsmFF8vbLmg4m1rHfVaE8u8bNawOWnKVkUz9BTRVz0130_assertion description "[We examined the expression of MK-1 in 10 urological tumor cell lines using flow cytometry and reverse transcription-polymerase chain reaction (RT-PCR) and in 15 cancer tissue specimens by immunohistochemical staining, and then compared it with that of carcinoembryonic antigen (CEA).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216688.RAscsmFF8vbLmg4m1rHfVaE8u8bNawOWnKVkUz9BTRVz0130_provenance.
NP216690.RAh4Dc7Gh4yfefHG0MbxF4rJs5ETp7k-Qf2-iSW2LcLpM130_assertion description "[Four weeks later, CD4-depleted SP-A-deficient mice had developed a more severe Pneumocystis infection than CD4-depleted WT (P. carinii pneumonia [PCP] scores of 3 versus 2, respectively).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216690.RAh4Dc7Gh4yfefHG0MbxF4rJs5ETp7k-Qf2-iSW2LcLpM130_provenance.
NP216694.RApeHvjlWox4L16WYr_ha24H7u9IcyGyOdIt9OT74pPGc130_assertion description "[A proportion of PCCs occurs in hereditary cancer syndromes, including multiple endocrine neoplasia Type 2 (MEN2), caused by mutations in the RET proto-oncogene, von Hippel-Lindau (VHL) disease, caused by VHL gene abnormalities, and the pheochromocytoma-paraganglioma (PCC-PGL) syndrome, caused by mutations in SDHB and SDHD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216694.RApeHvjlWox4L16WYr_ha24H7u9IcyGyOdIt9OT74pPGc130_provenance.
NP216696.RAp6IB1wfk-Sg8VFifRJnJYOFc4ppY_-JhcpuDoVwKoIg130_assertion description "[ATR-X is characterized by severe mental retardation, mild HbH disease, dysmorphic facies, and genital and skeletal abnormalities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216696.RAp6IB1wfk-Sg8VFifRJnJYOFc4ppY_-JhcpuDoVwKoIg130_provenance.
NP216699.RAv81V4mMYjbWnN3W-mX13tcMspKppJVnqz4XZ6aYf6gM130_assertion description "[Furthermore, stage IB endometrial cancer was associated with a higher VEGF-A protein/mRNA ratio and lower miR-214*, -221 and -222 expression in comparison with stage IA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216699.RAv81V4mMYjbWnN3W-mX13tcMspKppJVnqz4XZ6aYf6gM130_provenance.
NP216707.RAi4xceBfRkbauRqCnUYyo_4JfU0qbGK_DhJW9X2aCms4130_assertion description "[HIV patients naive to ARV were randomized to receive zidovudine (AZT), lamivudine (3TC) with efavirenz (EFV) or tenofovir disoproxil fumarate (TDF) with emtricitabine (FTC) and EFV.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216707.RAi4xceBfRkbauRqCnUYyo_4JfU0qbGK_DhJW9X2aCms4130_provenance.
NP216712.RAqguncFDR2UmDxc2wLZnRvdo73IaoPEkD3oStvCbxZpQ130_assertion description "[Therapy-related MDS (t-MDS) should be classified according to the involved agents.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216712.RAqguncFDR2UmDxc2wLZnRvdo73IaoPEkD3oStvCbxZpQ130_provenance.
NP216713.RAqu_Zux5k8JncBIQ3IncySL2EenHftjm2F8ja938Z7XA130_assertion description "[Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216713.RAqu_Zux5k8JncBIQ3IncySL2EenHftjm2F8ja938Z7XA130_provenance.
NP216717.RAkGfs80EwQibTQyzlVOMMREg2ouLLCK8_uzIF49RPIoU130_assertion description "[The compound genotype KIR3DS1/HLA-B Bw4-80I, which presumably favors natural killer cell activation, has been implicated in protection against HIV disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216717.RAkGfs80EwQibTQyzlVOMMREg2ouLLCK8_uzIF49RPIoU130_provenance.
NP216720.RAkhTnVwQ_8R6GcuVSlTxkGUj0nNPLGJj-8JdV6ugxkyo130_assertion description "[These data suggest that HTRA1 and HTRA3 mRNA and protein levels decrease with increasing grades of EC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216720.RAkhTnVwQ_8R6GcuVSlTxkGUj0nNPLGJj-8JdV6ugxkyo130_provenance.
NP216724.RAucRZv79qR9eQvqUpEiR27BiIhysXzuWzgHVpzhhzzDM130_assertion description "[A del(X)(p11) carrying SRY sequences in an infant with ambiguous genitalia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216724.RAucRZv79qR9eQvqUpEiR27BiIhysXzuWzgHVpzhhzzDM130_provenance.
NP216725.RArH9hV-vnXSbPCQpLt4HjN5MbM-s0UXdW3fvSREJo20g130_assertion description "[In support of this hypothesis, we have investigated the ultrastructure of the ID in mouse hearts from control and dilated cardiomyopathy (DCM) models, the MLP-null and a cardiac-specific β-catenin mutant, cΔex3, as well as in human left ventricle from normal and DCM samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216725.RArH9hV-vnXSbPCQpLt4HjN5MbM-s0UXdW3fvSREJo20g130_provenance.
NP216728.RAtRd2exW0JIDfdgkd2Bo2mgZy4WZBEA6Yl2lHm82uYuk130_assertion description "[Currently, SHOX mutations occur with an estimated incidence of roughly 1 in 1000 newborns, making mutations of this gene one of the most common genetic defects associated with growth failure and skeletal deformities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216728.RAtRd2exW0JIDfdgkd2Bo2mgZy4WZBEA6Yl2lHm82uYuk130_provenance.
NP216734.RAtUqQ7i_MQl4hh3VvKFiBkQi02P_GnkSbzFVu9X3XL8E130_assertion description "[Hormonal regulation of transforming growth factor beta-2 expression in human prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216734.RAtUqQ7i_MQl4hh3VvKFiBkQi02P_GnkSbzFVu9X3XL8E130_provenance.
NP216747.RAv3ZSjQ7qIBLbc32SjDTXiN4VREuZteAdR3sOMTXXzpY130_assertion description "[Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216747.RAv3ZSjQ7qIBLbc32SjDTXiN4VREuZteAdR3sOMTXXzpY130_provenance.
NP216755.RAsspwRkeiqfPNjlHPfn6kYRr3F21CMGrYV4d9iXg3mjY130_assertion description "[The International Life Sciences Institute Alternative Carcinogenicity Testing (ILSI ACT) Workshop concluded with a panel discussion that addressed the framework issue of the appropriate application of alternative models to human cancer risk assessment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216755.RAsspwRkeiqfPNjlHPfn6kYRr3F21CMGrYV4d9iXg3mjY130_provenance.
NP216762.RAp6V58jO50pvJnhQcaI-5InN6ZA3POPB4rIVabo9SOAU130_assertion description "[Pediatric non-Hodgkin lymphoma (NHL) is a common and fascinating group of diseases with distinctive underlying genetic events that characterize the major histologic subtypes: diffuse large B-cell lymphoma, Burkitt lymphoma, anaplastic large cell lymphoma and lymphoblastic lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216762.RAp6V58jO50pvJnhQcaI-5InN6ZA3POPB4rIVabo9SOAU130_provenance.
NP216766.RAkJ_gCKsGI8SjM2Ymt-iJ3NgCZWMWGmVbY81eRo36n_M130_assertion description "[Our studies revealed TGF-beta 1 and -beta 2 mRNA in dermal and subcutaneous infiltrating cells in both acute and chronic PSS, but also in the other inflammatory skin disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216766.RAkJ_gCKsGI8SjM2Ymt-iJ3NgCZWMWGmVbY81eRo36n_M130_provenance.
NP216769.RAhk4imim0QOfEjzNIVGirWOYozxS2A__zcNbpsUMS1iM130_assertion description "[In this study, 10 to 25 micromol/L curcumin inhibited 253JB-V and KU7 bladder cancer cell growth, and this was accompanied by induction of apoptosis and decreased expression of the proapoptotic protein survivin and the angiogenic proteins vascular endothelial growth factor (VEGF) and VEGF receptor 1 (VEGFR1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216769.RAhk4imim0QOfEjzNIVGirWOYozxS2A__zcNbpsUMS1iM130_provenance.
NP216776.RAtV2Y3L0JWC-jofxhX9KwBOlJXMHrCakrY2JpF53VWYY130_assertion description "[Mutations in the SCR19-20 domains of factor H were less frequent in P-aHUS patients compared with non-pregnancy-related aHUS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216776.RAtV2Y3L0JWC-jofxhX9KwBOlJXMHrCakrY2JpF53VWYY130_provenance.
NP216778.RAjMekqNYvuymYnndh3ic2PMFaPoRLPuvASRcWPYOHmos130_assertion description "[Fifteen patients received anakinra for up to 39 months, all of whom achieved serologic remission and complete resolution of fever, rash, conjunctivitis, and rheumatic symptoms, without any adverse effects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216778.RAjMekqNYvuymYnndh3ic2PMFaPoRLPuvASRcWPYOHmos130_provenance.
NP216794.RAmxb6bXFdVmsxu3PI7Sy2OyoT4Ulp8anBHCJp67RJek4130_assertion description "[Polymerase chain reaction and direct DNA sequencing of the entire coding regions of EXT1 and 2 for the nine patients revealed a novel pathogenic mutation, insertion of a T in exon 2 (c.72-73 insT) of EXT2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216794.RAmxb6bXFdVmsxu3PI7Sy2OyoT4Ulp8anBHCJp67RJek4130_provenance.
NP216796.RAuP51iI2uEjYkrHbrHD_KO8Ts0g-abPzML2rvq7GNUQY130_assertion description "[We found that MIF was increased in patients with pSS compared with healthy controls (p < 0.01).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216796.RAuP51iI2uEjYkrHbrHD_KO8Ts0g-abPzML2rvq7GNUQY130_provenance.
NP216799.RAiQt9D3bP6pXEHe4Hk0ek_s_gPmn2T7CPZ-GGIa6CP4Y130_assertion description "[Additionally, there was significantly increased PEDF mRNA (2.14+/-0.12 versus 0.30+/-0.05 in the control group; p=0.00002) in the liver metastases after pretreatment with angiostatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216799.RAiQt9D3bP6pXEHe4Hk0ek_s_gPmn2T7CPZ-GGIa6CP4Y130_provenance.
NP216803.RAsaM47niINmV8dO7K7yCuVJXIetYGwjLZUmIitLJg0TU130_assertion description "[Early events induced by BPA in epithelial-stromal cocultures derived from the contralateral tissue of patients with breast cancer included gene expression patterns which facilitate apoptosis evasion, endurance of microenvironmental stress, and cell cycle deregulation without a detectable increase in cell numbers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216803.RAsaM47niINmV8dO7K7yCuVJXIetYGwjLZUmIitLJg0TU130_provenance.
NP216804.RAi7TdKZ3wqALR5Zmqx8wmYgWNx5pyKgZp-r7_M83MJrE130_assertion description "[These tumors have been linked to endocrinopathies, such as Cushing disease and congenital adrenal hyperplasia, which involve overproduction of adrenocorticotropic hormone.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216804.RAi7TdKZ3wqALR5Zmqx8wmYgWNx5pyKgZp-r7_M83MJrE130_provenance.
NP216805.RAvK6zsSZrZub3Jaea6Yu5kUwbsiyHxqz--ryzNCjT918130_assertion description "[RASSF2, RASSF4, RASSF5 and RASSF6 are also epigenetically inactivated in cancer but have not been analysed in as wide a range of malignancies as RASSF1A.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216805.RAvK6zsSZrZub3Jaea6Yu5kUwbsiyHxqz--ryzNCjT918130_provenance.
NP216808.RAkaJxnaoCl0AiShm4cb14h3GagtQ06qb5K7yfCDyMG3M130_assertion description "[Genetic linkage studies have linked congenital contractural arachnodactyly (CCA), a usually mild heritable connective-tissue disorder, to FBN2, the fibrillin gene on chromosome 5.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216808.RAkaJxnaoCl0AiShm4cb14h3GagtQ06qb5K7yfCDyMG3M130_provenance.
NP216809.RAg_G1JHpFIJV0oy3JPzHNkKIwUJh-Q9cUXh2bb-fHais130_assertion description "[Missense and/or nonsense mutations of p53 were detected in 3 (10.7%) of 28 diffuse large B-cell lymphomas (DLBLs) and 2 (15.4%) of 13 T-cell NHLs (15.4%).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216809.RAg_G1JHpFIJV0oy3JPzHNkKIwUJh-Q9cUXh2bb-fHais130_provenance.
NP216810.RAp9mexfWhHRGQv8-Dl2rRrfePPK-D0QrGjFEDaWD4cvg130_assertion description "[Stable transfection of primary cutaneous melanoma SB-2 cells with the dominant-negative AP-2B gene was confirmed by RT--PCR and Northern blot analyses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216810.RAp9mexfWhHRGQv8-Dl2rRrfePPK-D0QrGjFEDaWD4cvg130_provenance.
NP216814.RAug9ZtXoq1zrex25MgljuQuk7Rof7aS2b4m1ZMW1eBZs130_assertion description "[In meningiomas (n = 24 tumors), the neoplastic cells, the ECM of the tumor, and the vessels were TN-C negative.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216814.RAug9ZtXoq1zrex25MgljuQuk7Rof7aS2b4m1ZMW1eBZs130_provenance.
NP216819.RAte33DIrkutayySxd995bQpI0qc-KTOJ2QbZ5TXJK4SE130_assertion description "[HSP70 mRNA levels in mononuclear blood cells (MBCs) were compared in 14 CJD patients (10 confirmed by histo-pathological study), 12 vascular dementia (VD) patients, 16 patients with Parkinson's disease and dementia (PD) and 14 nondemented control subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216819.RAte33DIrkutayySxd995bQpI0qc-KTOJ2QbZ5TXJK4SE130_provenance.
NP216820.RAoRtWUCw4-CNjPC9C_Vm7kJOoP1aWmmtnyQ5NnyzvjSw130_assertion description "[Toll-like receptor 2 (TLR2) and TLR4 have been found to transduce, respectively, peptidoglycan (PGN) and lipopolysaccharide (LPS) signals for the activation of NF-kappaB and the production of inflammatory cytokines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216820.RAoRtWUCw4-CNjPC9C_Vm7kJOoP1aWmmtnyQ5NnyzvjSw130_provenance.
NP216822.RAgqKw2em8P8VWJ59V_1CU9vm9HZiTRucB8p78-HP1_J0130_assertion description "[The Arg16Gly polymorphism of human beta2-adrenoreceptor is associated with type 2 diabetes in Taiwanese people.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216822.RAgqKw2em8P8VWJ59V_1CU9vm9HZiTRucB8p78-HP1_J0130_provenance.
NP216825.RAuzaGLKflrspHprh0_9OWJMkaQ23aixSQlzZRViusm9Y130_assertion description "[We studied a new FISH method to detect CHIC2 deletion, FIP1L1/PDGFRA fusion and PDGFRA translocation in patients with myeloid neoplasms associated with eosinophilia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216825.RAuzaGLKflrspHprh0_9OWJMkaQ23aixSQlzZRViusm9Y130_provenance.
NP216829.RAlQmNtoxsbRuPEEzEBhojq7FK01MJ0Kh2nZ6m8CsANOs130_assertion description "[Genetic variation in CYP27B1 is associated with congestive heart failure in patients with hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216829.RAlQmNtoxsbRuPEEzEBhojq7FK01MJ0Kh2nZ6m8CsANOs130_provenance.
NP216830.RAkTi11CspiJqAgCOpDbGKfIifHDxVXKzUmhVwqh3BHA0130_assertion description "[These results do not support a role for mutations in the class I beta-tubulin gene in the intrinsic resistance of renal cancer to TBAs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216830.RAkTi11CspiJqAgCOpDbGKfIifHDxVXKzUmhVwqh3BHA0130_provenance.
NP216833.RApWz6pKRPgfYUi91MCupbHef11Ofc_BWsUCr1ZQsK-VU130_assertion description "[The patients were assessed with blood pressure measurements, ambulatory blood pressure monitoring, body mass index (BMI), carotid artery intima-media thickness (IMT), flow-mediated dilation (FMD) of the brachial artery, echocardiography, and urinary albumin excretion (UAE) level.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216833.RApWz6pKRPgfYUi91MCupbHef11Ofc_BWsUCr1ZQsK-VU130_provenance.
NP216841.RAkQG8LoO8vP17--z0eawAcBmIbS6ujslJyloY1zHQ3o0130_assertion description "[PDE10A inhibitors: novel therapeutic drugs for schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216841.RAkQG8LoO8vP17--z0eawAcBmIbS6ujslJyloY1zHQ3o0130_provenance.
NP216844.RAkQqixXYS7VdXxt_d2ii6ixZ3V_hlWzaCreBsyQKy1Q8130_assertion description "[Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216844.RAkQqixXYS7VdXxt_d2ii6ixZ3V_hlWzaCreBsyQKy1Q8130_provenance.
NP216846.RAuo3X-j7SzeYsGyBK1jUQ_TUsP1LdX9zD-7ugE3K6BCg130_assertion description "[Acute promyelocytic leukemia (APL) represents the AML subset disclosing higher WT1 expression levels; however, no WT1 studies specifically focused on APL have been conducted.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216846.RAuo3X-j7SzeYsGyBK1jUQ_TUsP1LdX9zD-7ugE3K6BCg130_provenance.
NP216849.RAnIDejpvCFDDZWMjmxo7PO4bAFnRDj9F5B5oiOTxtxco130_assertion description "[Our results demonstrate that LS mutations have dominant-negative effects in vivo, identify enhanced mTOR activity as critical for causing LS-associated HCM, and suggest that TOR inhibitors be considered for treatment of HCM in LS patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP216849.RAnIDejpvCFDDZWMjmxo7PO4bAFnRDj9F5B5oiOTxtxco130_provenance.

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