Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP222898.RArrhLOLqIp7biM9-iv6S4lLneGDw7flxi34f3xu4EeMo130_assertion description "[These results suggest that the 5178A genotype of mitochondrial ND2 gene polymorphism is protective against MI; and this effect would explain, at least in part, its contribution to longevity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222898.RArrhLOLqIp7biM9-iv6S4lLneGDw7flxi34f3xu4EeMo130_provenance.
- NP222902.RAsfuieIyi2wpapzi3FHRcrFr_9K9sqpBbe-0-LrTXEgc130_assertion description "[Here, we examined 70 microsatellite unstable primary human cancers and we report that MRE11 mutations occur in 83.7 and 50% of the colorectal and endometrial cancers, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222902.RAsfuieIyi2wpapzi3FHRcrFr_9K9sqpBbe-0-LrTXEgc130_provenance.
- NP222903.RAuwG53cAffeAV__IoJxyfKaJ4WLZFtRmfswbjJcAFhy4130_assertion description "[We show here that Skp2 expression correlates directly with grade of malignancy and inversely with p27 levels in human lymphomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222903.RAuwG53cAffeAV__IoJxyfKaJ4WLZFtRmfswbjJcAFhy4130_provenance.
- NP222911.RAv4S0pivOd2jXuf2Pn25yzxUWNcUXycIHQJNA9uTfhiI130_assertion description "[Using a rat model of IPF, we explored the role of the proangiogenic and antiapoptotic growth factor VEGF in the vascular remodeling that underlies PH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222911.RAv4S0pivOd2jXuf2Pn25yzxUWNcUXycIHQJNA9uTfhiI130_provenance.
- NP222913.RAsLB-y6mH2BW0oTRWTM587329P_H5dxZunD5bFhi-QGY130_assertion description "[We investigated mechanisms of anti-CD20-mediated immune modulation using 2 paradigms of experimental autoimmune encephalomyelitis (EAE).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222913.RAsLB-y6mH2BW0oTRWTM587329P_H5dxZunD5bFhi-QGY130_provenance.
- NP222916.RAiChJXSxlUU5S5-8TDwSDUMkpojWSKwCH-ObtAC7nnDM130_assertion description "[Point mutations in LRRK2 cause autosomal dominant Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222916.RAiChJXSxlUU5S5-8TDwSDUMkpojWSKwCH-ObtAC7nnDM130_provenance.
- NP222922.RAqnmJHde8lMq9ESH3PL1kOCl5v_KgjiNzdHQVzHh6cc0130_assertion description "[To determine if the MCC, DCC or p53 gene is associated with susceptibility to hereditary non-polyposis colorectal cancer (HNPCC), these genes in normal cells from 12 HNPCC patients were analysed by polymerase chain reaction-single strand conformation polymorphism analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222922.RAqnmJHde8lMq9ESH3PL1kOCl5v_KgjiNzdHQVzHh6cc0130_provenance.
- NP222923.RAlusok2qxdeqly96nXWVKbKrvEIH-2z9_6yL4HzyUzpU130_assertion description "[The present study suggests that polymorphisms in OPRD1 are relevant for cocaine addiction in the African American population and provides additional support for a broad role for OPRD1 variants in drug dependence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222923.RAlusok2qxdeqly96nXWVKbKrvEIH-2z9_6yL4HzyUzpU130_provenance.
- NP222931.RAnI4Yf1Dusd2iVKmZ1YfhgUgsjaG5YqBGB6P-6gu5GAY130_assertion description "[Quantification of MITF mRNA expression might be clinically useful to predict metastasis and survival of patients with RCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222931.RAnI4Yf1Dusd2iVKmZ1YfhgUgsjaG5YqBGB6P-6gu5GAY130_provenance.
- NP222934.RAo9ilWP4LMj78ARDSCn9hf0gARIg2oGwkrn6b5gfrpaw130_assertion description "[Protein 4.1B is a 4.1/ezrin/radixin/moesin domain-containing protein whose expression is frequently lost in a variety of human tumors, including meningiomas, non-small-cell lung cancers, and breast carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222934.RAo9ilWP4LMj78ARDSCn9hf0gARIg2oGwkrn6b5gfrpaw130_provenance.
- NP222935.RAgKmXoe4PKGSfkp2S7YilGwgbWgMndMdsFpww9mXvnCE130_assertion description "[Here we investigate the capability of protein 14-3-3, total-tau (t-tau), threonin-181-phosphorylated tau (p-tau), and neuron-specific enolase (NSE) in cerebrospinal fluid (CSF) together with the prion protein gene genotype to discriminate patients with sCJD (n=21) from neurological controls (n=164) and Alzheimer's disease (AD) patients (n=49).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222935.RAgKmXoe4PKGSfkp2S7YilGwgbWgMndMdsFpww9mXvnCE130_provenance.
- NP222938.RAodk3ImXMsILoEHtiXSDql0fzGUf0kyuPFu_nXBaa80k130_assertion description "[We investigated whether SDHB immunohistochemistry could effectively discriminate between SDH-related and non-SDH-related phaeochromocytomas and paragangliomas in large retrospective and prospective tumour series.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222938.RAodk3ImXMsILoEHtiXSDql0fzGUf0kyuPFu_nXBaa80k130_provenance.
- NP222939.RAo5K05gJXwb3chEHo5KSgMuN8-A75YvCV9VsfkB_bZog130_assertion description "[Possession of a CCL3L1 copy number lower than the population average was associated with markedly enhanced HIV/acquired immunodeficiency syndrome (AIDS) susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222939.RAo5K05gJXwb3chEHo5KSgMuN8-A75YvCV9VsfkB_bZog130_provenance.
- NP222954.RAmqplUv9p7hXILuq00ODudy4oFdujsrQAUPFmuxBXNIk130_assertion description "[The expressions of CCR7 and CXCR4 mRNA were analyzed by RT-PCR in 10 human gastric cancer cell lines and in 43 gastric cancer tissues, and in an additional 307 gastric cancer tissues by immunohistochemistry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222954.RAmqplUv9p7hXILuq00ODudy4oFdujsrQAUPFmuxBXNIk130_provenance.
- NP222955.RAv6AbxnXPM__9f0RaUR_U-zkTSM0Ceqnk2RvCu5Ukpsc130_assertion description "[Our results revealed that the frequencies of GSTO1 and GSTO2 genotypes were not significantly different between HNSCC cases and controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222955.RAv6AbxnXPM__9f0RaUR_U-zkTSM0Ceqnk2RvCu5Ukpsc130_provenance.
- NP222956.RAgIbTFtbQh5bp7C5PInTNG-vBxXXwv7lPFqBhcyY-p_E130_assertion description "[However, recent immunolabeling experiments have demonstrated extensive Spastin expression in the cortex and striatum.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222956.RAgIbTFtbQh5bp7C5PInTNG-vBxXXwv7lPFqBhcyY-p_E130_provenance.
- NP222959.RAo2sZCLEjkjqREYE_86hF-H1zRRyolzGyRj_180VY9b0130_assertion description "[In a case-control sample that has shown the well established associations between AMD and variants in CFH, CFB and C3 there was absence of association with SNPs in CFP, CD46, CD55 and CD59.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222959.RAo2sZCLEjkjqREYE_86hF-H1zRRyolzGyRj_180VY9b0130_provenance.
- NP222969.RAimFWqqHmwr2-_1xr3DZzLC0aL3Q0XdwoN5rs5jTq3sc130_assertion description "[We tested the hypothesis that GH could improve cardiac and renal function in volume overload-induced heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222969.RAimFWqqHmwr2-_1xr3DZzLC0aL3Q0XdwoN5rs5jTq3sc130_provenance.
- NP222970.RAngHjx5_j01GmM3c2X9aaWAVx5A9-1MFzWrV4bTjYTV4130_assertion description "[Here, we report the identification of mutations in transport protein particle complex 11 (TRAPPC11) in three individuals of a consanguineous Syrian family presenting with LGMD and in five individuals of Hutterite descent presenting with myopathy, infantile hyperkinetic movements, ataxia, and intellectual disability.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222970.RAngHjx5_j01GmM3c2X9aaWAVx5A9-1MFzWrV4bTjYTV4130_provenance.
- NP222978.RAtjvI6BgpHGCyIx19SCxaX7aSsTJVPmB5IPzfSEelcmE130_assertion description "[Our aim was to assess the value of microalbuminuria (MA) for predicting clinical neurological disease and overt nephropathy in TTR-related amyloidosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP222978.RAtjvI6BgpHGCyIx19SCxaX7aSsTJVPmB5IPzfSEelcmE130_provenance.
- NP223001.RAnRa2sNerSV318UfCyicVUaXinPUCqOojED-hziUEjCM130_assertion description "[Treatment of the cells with curcumin and siRNA-based knockdown of CXCL1 and -2 induce apoptosis, inhibit proliferation and downregulate several important metastasis-promoting factors like COX2, SPARC and EFEMP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223001.RAnRa2sNerSV318UfCyicVUaXinPUCqOojED-hziUEjCM130_provenance.
- NP223007.RAjwEYkJLH486OWzqElrhcpR0jcA4B7t8MTLwJJLY52ME130_assertion description "[Expression of IL-1 alpha, IL-1 beta, IL-2, IL-4, IL-6, IL-10, IL-12, IFN-gamma, TGF-beta, TNF-alpha, and PDGF was examined in 28 patients with IgA nephropathy (IgAN), 20 patients with non-IgA mesangial proliferative glomerulonephritis (mesPGN), and 19 healthy controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223007.RAjwEYkJLH486OWzqElrhcpR0jcA4B7t8MTLwJJLY52ME130_provenance.
- NP223009.RAnq0ZsQuD2uMND8MRXK_wUCYo4Y2GdkWAoHHgdskmemU130_assertion description "[The purpose of this study was to determine whether inhibition of the epidermal growth factor receptor (EGFR) is a plausible therapeutic strategy in pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223009.RAnq0ZsQuD2uMND8MRXK_wUCYo4Y2GdkWAoHHgdskmemU130_provenance.
- NP223016.RAp8ONYGF3eUtfi4ti2K4AKPEyOEs_axAU4u9RXi9S434130_assertion description "[Our data suggest that IDH1 or IDH2 mutation plays a role in early tumor progression of several types of glioma and might arise from a common glial precursor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223016.RAp8ONYGF3eUtfi4ti2K4AKPEyOEs_axAU4u9RXi9S434130_provenance.
- NP223018.RApiz7o7l3ErtySjEUqJizw6DGFApagaHs8HPv6jqxBOs130_assertion description "[Carrier detection of sialidosis with partial beta-galactosidase deficiency by the assay of lysosomal sialidase in lymphocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223018.RApiz7o7l3ErtySjEUqJizw6DGFApagaHs8HPv6jqxBOs130_provenance.
- NP223022.RAoVlN5ZiCXktRAKqnEu2JyUA2BZzfq58hDyB7Kvr6UZs130_assertion description "[We investigated the following SNPs: -1082, -819, -592 in the promoter region of IL10 in a normal (control) population and selected diseases: breast cancer (BrCa), systemic lupus erythematosus (SLE), and B-cell chronic lymphocytic leukemia (B-CLL) by denaturing high-performance liquid chromatography (DHPLC) and found distinct genotype and haplotype patterns.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223022.RAoVlN5ZiCXktRAKqnEu2JyUA2BZzfq58hDyB7Kvr6UZs130_provenance.
- NP223023.RAgBqMWGlT_S_jZMjJjgzs15xkLSRoMocVdxXz-6KLTeQ130_assertion description "[Homozygous deletions of the CDKN2/p16 gene in dural hemangiopericytomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223023.RAgBqMWGlT_S_jZMjJjgzs15xkLSRoMocVdxXz-6KLTeQ130_provenance.
- NP223031.RAoQiG-drB03OgGn_mjGXQyVzkYyS2ESCTtwHRoh3Y-LA130_assertion description "[Metabolism of albumin and immunoglobulins in the nephrotic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223031.RAoQiG-drB03OgGn_mjGXQyVzkYyS2ESCTtwHRoh3Y-LA130_provenance.
- NP223034.RAvNWU26hCrOpSResNqrcu0w6S-BAOWhO3xnSiL2kT_AE130_assertion description "[Furthermore, chronic treatment of aged Tg2576 mice with energy inhibitors increases levels of eIF2alpha-P, BACE1, Abeta, and amyloid plaques.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223034.RAvNWU26hCrOpSResNqrcu0w6S-BAOWhO3xnSiL2kT_AE130_provenance.
- NP223039.RApfRwpJgqno21Wfgl0ooAF6J0u5wqNp8Iy_k6bNmPDgs130_assertion description "[To confirm that aggressive PTCs were characterized by EMT, 34 additional PTCs were examined for expression of vimentin, a hallmark of EMT.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223039.RApfRwpJgqno21Wfgl0ooAF6J0u5wqNp8Iy_k6bNmPDgs130_provenance.
- NP223041.RAvlzaLh7Ayf1horG222JDOIhPEf3jdxn13kwhqDwSBOA130_assertion description "[The MIF risk genotypes and H. pylori conferred a joint ARP of 93.2% to gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223041.RAvlzaLh7Ayf1horG222JDOIhPEf3jdxn13kwhqDwSBOA130_provenance.
- NP223048.RAj8olro5TPe8lAQOq141Ndks9MpMsqSkMgKACVXQ0OoU130_assertion description "[The study suggests a connection between CD133 and EGR1 and emphasises the importance of the EGR1/TCF4/CD133/LGR5 network in CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223048.RAj8olro5TPe8lAQOq141Ndks9MpMsqSkMgKACVXQ0OoU130_provenance.
- NP223060.RArtAIrWrtnFHKItF3TKAbvZKf0fFiB-U2uqTEf4-tV3A130_assertion description "[TBC1D24 in the mouse inner ear was immunolocalized predominantly to spiral ganglion neurons, indicating that DFNB86 deafness might be an auditory neuropathy spectrum disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223060.RArtAIrWrtnFHKItF3TKAbvZKf0fFiB-U2uqTEf4-tV3A130_provenance.
- NP223063.RAh3grrRtRElvfM9FSRgWEQrR1K734bdGA2iMIRZ6IknA130_assertion description "[Newborn metabolic disease screening uses blood dried on filter paper (DBS) to prospectively identify candidate newborns affected with PKU via an elevated concentration of phenylalanine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223063.RAh3grrRtRElvfM9FSRgWEQrR1K734bdGA2iMIRZ6IknA130_provenance.
- NP223065.RAsVL7YvXacbSaSCRVl1f4ZXQ-a0C_syYxJsHZWr7WLMI130_assertion description "[In this study we have investigated the effect of two functional polymorphisms of the MTHFR gene, MTHFR_677_C > T and MTHFR_1298_A > C, on breast and ovarian cancer risk in Polish BRCA1 mutation carriers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223065.RAsVL7YvXacbSaSCRVl1f4ZXQ-a0C_syYxJsHZWr7WLMI130_provenance.
- NP223067.RAnBYFAYUrWT-zee3jITRNK7BBLu07oR0qQjaKlJA0GDc130_assertion description "[By contrast, 18 MSI+ colorectal cancers (13 cancer cell lines and five primary tumors) with mismatch repair defects exhibited six mutations in three of the 17 genes (SREBP-2, TAN-1, GR6) (P<0.000003 compared to all other cancers tested).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223067.RAnBYFAYUrWT-zee3jITRNK7BBLu07oR0qQjaKlJA0GDc130_provenance.
- NP223068.RAnomrTwPQR-e5PstQGSZBbtbKwq9E9VBwLYaK7IGU8Oo130_assertion description "[Second-site mutation in the Wiskott-Aldrich syndrome (WAS) protein gene causes somatic mosaicism in two WAS siblings.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223068.RAnomrTwPQR-e5PstQGSZBbtbKwq9E9VBwLYaK7IGU8Oo130_provenance.
- NP223075.RAnrmO-xQKX6vqCM-0FAeBlH-rsLhNshajRtYQDSHB5Vw130_assertion description "[Tumstatin is an anti-angiogenic collagen IV α3 fragment, levels of which are reduced in the airways of asthmatics.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223075.RAnrmO-xQKX6vqCM-0FAeBlH-rsLhNshajRtYQDSHB5Vw130_provenance.
- NP223077.RAtsJdSth-IlKAFGElmV0pwVYVE4b0SgJj0KDbdl5nwdI130_assertion description "[Clinically, normal ovaries from BRCA1 heterozygotes do not show evidence of premalignant alterations in histology, molecular markers, cell proliferation, or apoptosis, indicating that such changes are likely rare.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223077.RAtsJdSth-IlKAFGElmV0pwVYVE4b0SgJj0KDbdl5nwdI130_provenance.
- NP223078.RAgkJnsAEv7_ZyT22gEaQTNckluzyDTRWX2Yx7y2UrVU0130_assertion description "[As a novel mechanism of lung tumorigenesis mediated by CYP2A6, we investigated the effects of cotinine on the suppression of apoptosis and promotion of lung tumor growth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223078.RAgkJnsAEv7_ZyT22gEaQTNckluzyDTRWX2Yx7y2UrVU0130_provenance.
- NP223079.RAs3Qzmalzjdt_mOaRga3NRFU_YS0-zuHsYd_oomVm95Y130_assertion description "[The series of photographs range from the hands of an individual with FLG mutations but no history of eczema, to the hands of individuals with typical and atypical filaggrin hand eczema, and finally to the hands of an individual with FLG mutations and hand eczema caused by exposure to irritants and allergens.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223079.RAs3Qzmalzjdt_mOaRga3NRFU_YS0-zuHsYd_oomVm95Y130_provenance.
- NP223086.RAmAUckR0YQVxa_6eBAEVy8y-GGawQQuHhR6-7uBT5jic130_assertion description "[The locus identified in this study for familial dilated cardiomyopathy, 1q32, is rich in candidate genes, such as MEF-2, renin, and helix loop helix DNA binding protein MYF-4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223086.RAmAUckR0YQVxa_6eBAEVy8y-GGawQQuHhR6-7uBT5jic130_provenance.
- NP223087.RAkhgVMkGSKDqMxc3XsjyHhT0wNRNibLoOlPgY-KM0M7w130_assertion description "[Compared to these DH lymphomas, BCL6(+)/MYC(+) DH lymphomas are far less common, and in fact most of these cases represent BCL2(+)/BCL6(+)/MYC(+) triple-hit lymphomas with involvement of BCL2 as well.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223087.RAkhgVMkGSKDqMxc3XsjyHhT0wNRNibLoOlPgY-KM0M7w130_provenance.
- NP223088.RAhv1HcFyBCQM-NOEssvfGC7VipoQABEZsoEK8svQgyvI130_assertion description "[Glycogen storage disease type 1a (GSD-1a), characterized by growth retardation, hypoglycemia, hepatomegaly, kidney enlargement, hyperlipidemia, hyperuricemia, and renal dysfunction, is caused by deficiencies in glucose-6-phosphatase (G6Pase), a key enzyme in glucose homeostasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223088.RAhv1HcFyBCQM-NOEssvfGC7VipoQABEZsoEK8svQgyvI130_provenance.
- NP223093.RAtrVqY9NBTD7MUuc7TmSYvpR3P-8IsJneF2ovtJgz0jI130_assertion description "[To investigate the expression and clinical significance of DEK, cyclin D1, insulin-like growth factor II (IGF-II), glypican 3 (GPC3), ribosomal phosphoprotein 0 (rpP0) mRNA in hepatocellular carcinoma (HCC) and its paraneoplastic tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223093.RAtrVqY9NBTD7MUuc7TmSYvpR3P-8IsJneF2ovtJgz0jI130_provenance.
- NP223099.RAiTJGYF91ngXeKNV4p39h3ebDlwLhtGL1XBD2InDYE9Y130_assertion description "[Most importantly, tumor formation from DLD-1-Gal7 cells was dramatically reduced compared with DLD-1-V cells when these cells were inoculated s.c. into severe combined immunodeficient mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223099.RAiTJGYF91ngXeKNV4p39h3ebDlwLhtGL1XBD2InDYE9Y130_provenance.
- NP223101.RAs5P7mOQaEXXv3d_o1zC1C0PLSjdKxii0lJ7TKuTuVmA130_assertion description "[Consenting patients (n = 2531) with significant coronary artery disease (> or =1 lesion of > or =70% stenosis) undergoing coronary arteriography were genotyped, grouped by statin prescription at hospital discharge, and prospectively followed-up for the outcomes of all-cause mortality and myocardial infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223101.RAs5P7mOQaEXXv3d_o1zC1C0PLSjdKxii0lJ7TKuTuVmA130_provenance.
- NP223104.RApOMpWp76R7WldwLkbq_Vqh6mjvS4fd39tH4tJycyaNc130_assertion description "[Mucopolysaccharidosis (MPS) type VI, the lysosomal storage disorder caused by the deficiency of arylsulfatase B (ARSB) activity, occurs in humans, cats, and rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223104.RApOMpWp76R7WldwLkbq_Vqh6mjvS4fd39tH4tJycyaNc130_provenance.
- NP223107.RAvpPenZaEyD0x2HJBV_C7BX-DsIgkVN9dzo0skWhV55A130_assertion description "[Here, we report that the promoter usage and expression levels of IGF2 and H19 were altered in cervical carcinoma showing loss of imprinting.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223107.RAvpPenZaEyD0x2HJBV_C7BX-DsIgkVN9dzo0skWhV55A130_provenance.
- NP223109.RAnI0Q0k7zp_7ISvBbRDz7kjMrs-OJhsdJYgl8LjzCwCI130_assertion description "[The three polymorphisms, namely -3826A-->G, an A-->C transition in the 5'-untranslated region (UTR) and Met229Leu, were not associated with type 2 diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223109.RAnI0Q0k7zp_7ISvBbRDz7kjMrs-OJhsdJYgl8LjzCwCI130_provenance.
- NP223113.RAjUXS1l87aqPw1Qbla3L5qp_Bfa_X9c4UZhph4uo7A_E130_assertion description "[A role for LIM kinase in cancer invasion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223113.RAjUXS1l87aqPw1Qbla3L5qp_Bfa_X9c4UZhph4uo7A_E130_provenance.
- NP223117.RAh1kwouIfovsVVNiCVYV6Y95d7fgztt7H42O5pqI1Z78130_assertion description "[A rare congenital ectodermal disorder characterized by ichthyosis follicularis, alopecia and photophobia has been designated the acronym IFAP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223117.RAh1kwouIfovsVVNiCVYV6Y95d7fgztt7H42O5pqI1Z78130_provenance.
- NP223118.RAp-gpCIdt7FoxhdHO4su_r6Y2rOsVjJqU6qAiLgyVZpE130_assertion description "[Type III galactosaemia is a hereditary disease caused by reduced activity in the Leloir pathway enzyme, UDP-galactose 4'-epimerase (GALE).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223118.RAp-gpCIdt7FoxhdHO4su_r6Y2rOsVjJqU6qAiLgyVZpE130_provenance.
- NP223122.RAnnrwKHLheOlMGeUZUnTY-2Dyas0Jc10HNjTsLCLeF_w130_assertion description "[Mouse monoclonal antibody 17-1A is specific for an antigen expressed on cells of human gastrointestinal malignancies and has been used in radioimmune imaging and therapy trials for patients with colon and pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223122.RAnnrwKHLheOlMGeUZUnTY-2Dyas0Jc10HNjTsLCLeF_w130_provenance.
- NP223132.RAnDOmMAD3wXvinI0d81StLqy_Y1PJIcbcL_Nu916S86Q130_assertion description "[In the esophagus, squamous cell carcinoma and adenocarcinoma are known to express COX-2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223132.RAnDOmMAD3wXvinI0d81StLqy_Y1PJIcbcL_Nu916S86Q130_provenance.
- NP223135.RApEMh0cpLaerMQcXf2jRr8mYvn1hw6PjuxxTqQDM_DCw130_assertion description "[Loss of estrogen receptor beta expression in malignant human prostate cells in primary cultures and in prostate cancer tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223135.RApEMh0cpLaerMQcXf2jRr8mYvn1hw6PjuxxTqQDM_DCw130_provenance.
- NP223136.RAo6yMDBu_j2MrVO0lID4X5WRD4V96vZJnA3WB-5GXpz8130_assertion description "[In conclusion, MDM2 and CDK4 immunostainings, which correlate with gene amplification, are helpful adjuncts to differentiate ALT-WDLPS from benign adipose tumors and to separate DDLPS from poorly differentiated sarcomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223136.RAo6yMDBu_j2MrVO0lID4X5WRD4V96vZJnA3WB-5GXpz8130_provenance.
- NP223137.RAvIF5zBwir5T646fYsFM10ZwmZMsa9dQKOCdKrRp6x3I130_assertion description "[CHIP is an E3 ubiquitin ligase that can induce ubiquitylation and degradation of many tumor-related proteins, and it has been reported to act as an upstream regulator in breast cancer; however, its role in human gliomas has not been evaluated yet.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223137.RAvIF5zBwir5T646fYsFM10ZwmZMsa9dQKOCdKrRp6x3I130_provenance.
- NP223141.RAvebtp72jej08b5FcAewuLk72FQ8YcMVrKLitjaNmSc8130_assertion description "[Moreover, there was no evidence of epistasis between the analyzed CEACAM6 variants and the main CD-associated NOD2, IL23R and ATG16L1 variants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223141.RAvebtp72jej08b5FcAewuLk72FQ8YcMVrKLitjaNmSc8130_provenance.
- NP223143.RAkW6Gml1nvfX8Sft4tlX2DxQ2s0qgYFnpTUnay_O5KVs130_assertion description "[Human group 1 CD1 molecules (CD1a, CD1b, and CD1c) bind a pool of lipid antigens expressed by mycobacteria and present them to specific T cells, thereby mediating an effective pathway for host defense against tuberculosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223143.RAkW6Gml1nvfX8Sft4tlX2DxQ2s0qgYFnpTUnay_O5KVs130_provenance.
- NP223147.RAs-K5PUPMIUOpKffO4WXkRbc6uqxo5WiHCZ1nwxXcvqY130_assertion description "[In this study, we characterized the cancer susceptibility of mice deficient in the expression of pRb and either of two related `pocket` proteins, p107 and p130, that are also inactivated by E7.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223147.RAs-K5PUPMIUOpKffO4WXkRbc6uqxo5WiHCZ1nwxXcvqY130_provenance.
- NP223158.RAnasBRRLNhjib2rqLFf37bJMp-sf7sDkU7rJ2nCpozrg130_assertion description "[Ocular albinism of the Nettleship-Falls type (OA1) and X-linked ichthyosis (XI) due to steroid sulfatase (STS) deficiency are cosegregating in three cytogenetically normal half-brothers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223158.RAnasBRRLNhjib2rqLFf37bJMp-sf7sDkU7rJ2nCpozrg130_provenance.
- NP223160.RAi1xh6cYcueM1qejFSfYw9f6IZPp9y-5M1n47MqZ2W90130_assertion description "[Moreover, there was a significantly higher probability of severe febrile neutropenia in patients with a variant ITPA allele among patients whose dose of mercaptopurine had been adjusted for TPMT genotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223160.RAi1xh6cYcueM1qejFSfYw9f6IZPp9y-5M1n47MqZ2W90130_provenance.
- NP223165.RAjHcd2g64gUfy0DO1YaPrcefLkKJe5FV5FAf3_9phMac130_assertion description "[Immunohistochemical staining with a polyclonal VEGF antibody was performed in 55 paraffin-embedded PCA, in which MVD had previously been determined, as well as in 5 prostatic adenomas (PA) and 20 adjacent normal prostate tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223165.RAjHcd2g64gUfy0DO1YaPrcefLkKJe5FV5FAf3_9phMac130_provenance.
- NP223167.RAr1bTywm8p3drGboq-3EYYFljm6UL9tceoQNwZk-RNbM130_assertion description "[Sections of four tumors, and corresponding adjacent areas, from patients with achalasia due to Chagas' disease were examined by immunohistochemistry for p53 and PCNA proteins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223167.RAr1bTywm8p3drGboq-3EYYFljm6UL9tceoQNwZk-RNbM130_provenance.
- NP223182.RAkVfrDau2T9BTAnE2Pm-jnfJbCoTLq5zn0n4_l_pSmzc130_assertion description "[The symptoms of atopic dermatitis (AD) are often aggravated by anxiety, and the serotonin transporter (5-HTT) has been shown to be of importance in this context.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223182.RAkVfrDau2T9BTAnE2Pm-jnfJbCoTLq5zn0n4_l_pSmzc130_provenance.
- NP223184.RAppxXy0mF9ESf8RMkU6uSU7rOMNgbzUTbIOlIjv7kfco130_assertion description "[SCA14 represented only 1.5% (7/454) of French ADCA families but none of the German families.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223184.RAppxXy0mF9ESf8RMkU6uSU7rOMNgbzUTbIOlIjv7kfco130_provenance.
- NP223191.RAqpNWySYBY3N9BALPXIF7FgGds2nDQlBqqXnJ8qS_T70130_assertion description "[Metachromatic leukodystrophy (MLD) is an autosomal recessive disorder due to arylsulfatase A (ARSA) deficiency that affects primarily the central nervous system.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223191.RAqpNWySYBY3N9BALPXIF7FgGds2nDQlBqqXnJ8qS_T70130_provenance.
- NP223193.RAoh1E4oEFWLSBjP-D3KyluxIm6LKR4Z_smjVRxNTrBkM130_assertion description "[The mechanism by which loss of C/EBPβ promoted the TGF-β response towards EMT, invasion and metastasis, was traced to a previously uncharacterized role of C/EBPβ as a transcriptional activator of genes encoding the epithelial junction proteins E-cadherin and coxsackie virus and adenovirus receptor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223193.RAoh1E4oEFWLSBjP-D3KyluxIm6LKR4Z_smjVRxNTrBkM130_provenance.
- NP223195.RAt2KOKt1xaL4qLHB7AOcfeozFEMUk-dqIuV7XV9BzlmY130_assertion description "[Importantly, tumors formed in the presence of p16(INK4A)-defective fibroblasts exhibited higher levels of active Akt, Cox-2, MMP-2 and MMP-9, showing their greater aggressiveness as compared with xenografts formed in the presence of p16(INK4A)-proficient fibroblasts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223195.RAt2KOKt1xaL4qLHB7AOcfeozFEMUk-dqIuV7XV9BzlmY130_provenance.
- NP223197.RArZ3T4JophdZDI06mNiB4gOj--7Gcl6tgKcu4wgt2WmY130_assertion description "[Additional findings, particularly elevation of CSF lactate, suggested mitochondrial cytopathy as an essential feature of the multisystem degeneration in these patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223197.RArZ3T4JophdZDI06mNiB4gOj--7Gcl6tgKcu4wgt2WmY130_provenance.
- NP223199.RAl3WUEyZPwfxXLECNJtPYjVZbyaAD2wODDTzqF9WhaBE130_assertion description "[Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223199.RAl3WUEyZPwfxXLECNJtPYjVZbyaAD2wODDTzqF9WhaBE130_provenance.
- NP223201.RAh0Lxt8yAVQfJjRbY4ggMaCRCiIcQ5dbUb8sFW70Gwmw130_assertion description "[We identified a LRRK2 mutation leading to the G2019S amino acid substitution in a 79-year-old woman with frontotemporal lobar degeneration with ubiquitinated neuronal intranuclear inclusions (FTLD-U/NII) and a possible family history of tremor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223201.RAh0Lxt8yAVQfJjRbY4ggMaCRCiIcQ5dbUb8sFW70Gwmw130_provenance.
- NP223202.RAlse54lCpYaeQI-RC_sVvkxe1HWtPkuRVGC8r8-5yLFc130_assertion description "[These results indicate the activation of IL-4/IL-4 receptor system in leukemic cells from some ATL patients and suggest the possible involvement of the system in the proliferation of leukemic cells and the leukemogenesis in ATL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223202.RAlse54lCpYaeQI-RC_sVvkxe1HWtPkuRVGC8r8-5yLFc130_provenance.
- NP223205.RAuyNeEl9FUvVA4Dn0nLViUU0ok0gySzzyDOnUzwWoIPQ130_assertion description "[Hereditary non-polyposis colorectal cancer (HNPCC, Lynch syndrome) is characterized by the development of cancer of the colorectum, endometrium and other cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223205.RAuyNeEl9FUvVA4Dn0nLViUU0ok0gySzzyDOnUzwWoIPQ130_provenance.
- NP223208.RAqm8ltpuyVyfGtxeN2wMt2NkDXJJXUd8AIWY5j8pCND0130_assertion description "[We analyzed the influence of I105V polymorphism of GSTP1 on clinico-pathological features and outcomes in 166 Chinese patients with metastatic colorectal carcinoma who had been treated with first-line FOLFOX-4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223208.RAqm8ltpuyVyfGtxeN2wMt2NkDXJJXUd8AIWY5j8pCND0130_provenance.
- NP223209.RAsRxx94vkPW0xtXlJ_35HEeLRgd4lUMkqEYxhreUWxXY130_assertion description "[We review studies that have identified a potential role for polymorphisms in the genes encoding the glutathione-S-transferases (GSTs), NAD(P) H: quinone oxidoreductase, myeloperoxidase, N-acetyltransferase (NATs), cytochrome P450 (CYP) 1A1 and 3A4, methylenetetrahydrofolate reductase (MTHFR), cystathionine-beta-synthase (CBS), and others in the etiology of primary or secondary acute leukemias, and therapy-related complications.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223209.RAsRxx94vkPW0xtXlJ_35HEeLRgd4lUMkqEYxhreUWxXY130_provenance.
- NP223212.RAtBB8WuFF3ZHpuAufMR059Nbi0RFHRL9nSSqvzTsTpwo130_assertion description "[The purpose of this study is to examine the association of HLA-B*1502 allele with CBZ-induced SJS/TEN in the mainland Han Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223212.RAtBB8WuFF3ZHpuAufMR059Nbi0RFHRL9nSSqvzTsTpwo130_provenance.
- NP223216.RAmOhzVKPSX7g4Sd05fEQwz7Y1OHDhr-Oj1sWeVvr_ln4130_assertion description "[USOD and SEDI immunohistochemistry of spinal cord sections from ALS cases resulting from SOD1 mutations (A4V and DeltaG27/P28) shows that inclusions within remaining motor neurons contain SOD1 with both an unfolded beta barrel and a disrupted dimer interface.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223216.RAmOhzVKPSX7g4Sd05fEQwz7Y1OHDhr-Oj1sWeVvr_ln4130_provenance.
- NP223217.RAv-lEOvQhcaQktz2kUZU_GcP6ULU6jPQbqDQIvr3y5aA130_assertion description "[These findings suggest that hU-II may play a novel role in pulmonary hypertension by promoting remodeling processes via activation of NADPH oxidases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223217.RAv-lEOvQhcaQktz2kUZU_GcP6ULU6jPQbqDQIvr3y5aA130_provenance.
- NP223231.RAi6PybmjxXVdq4LDFKWH4B1KAQ8aWnr3R1C2ozJJdKZA130_assertion description "[In conclusion, within the Chinese population, the c.297T>C p.Ala99Ala polymorphism of the GIGYF2 gene may be associated with an increased risk of developing PD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223231.RAi6PybmjxXVdq4LDFKWH4B1KAQ8aWnr3R1C2ozJJdKZA130_provenance.
- NP223233.RAo6mEtgjJgbvVVgfLCEMiyD3msrcQ8kqJ-1q_Uxwqy-4130_assertion description "[These findings point to a role for BDNF polymorphisms in Chinese Han children with asthma and may inform future genetic or biological studies on childhood asthma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223233.RAo6mEtgjJgbvVVgfLCEMiyD3msrcQ8kqJ-1q_Uxwqy-4130_provenance.
- NP223243.RAlXthUisEpdSzUHSNK9BpiVA_4B0R9HrNlii_HzCK3n8130_assertion description "[Of these, the CD7 expression in CD4(+) T cells discriminates between HL and reactive LAD, suggesting that this could be a useful and practical adjunctive tool in the diagnosis of HL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223243.RAlXthUisEpdSzUHSNK9BpiVA_4B0R9HrNlii_HzCK3n8130_provenance.
- NP223253.RAvKNMxdSsW4iVf5VDQvc0YXK9wkZQ8ZkXwOaUMNKIDn4130_assertion description "[Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223253.RAvKNMxdSsW4iVf5VDQvc0YXK9wkZQ8ZkXwOaUMNKIDn4130_provenance.
- NP223260.RAjVvPy-sROuenMwMMRGFKCnXiQgRrvxuMVsfBrSFgTLY130_assertion description "[We describe mutations in the PML nuclear body protein Sp110 in the syndrome veno-occlusive disease with immunodeficiency, an autosomal recessive disorder of severe hypogammaglobulinemia, combined T and B cell immunodeficiency, absent lymph node germinal centers, absent tissue plasma cells and hepatic veno-occlusive disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223260.RAjVvPy-sROuenMwMMRGFKCnXiQgRrvxuMVsfBrSFgTLY130_provenance.
- NP223269.RAjUtUDWdQV5KLyD9Ex8ZkkVQ8xqxy1fZX8goenxO4UNk130_assertion description "[Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223269.RAjUtUDWdQV5KLyD9Ex8ZkkVQ8xqxy1fZX8goenxO4UNk130_provenance.
- NP223273.RAnJPIN9_Kb2pN41903EmtaNxGBRFlLfhgSZxXmhYeKFo130_assertion description "[In vivo, G92A replicated well in subcutaneous xenografts of human hepatoma cells (Hep3B) in athymic mice, but not in non-hepatoma subcutaneous tumors (PC3 and HeLa), whereas, hrR3 replicated well in both tumor types.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223273.RAnJPIN9_Kb2pN41903EmtaNxGBRFlLfhgSZxXmhYeKFo130_provenance.
- NP223274.RArnLWIPQJh7WYcCUsbIuXC_y_XtYPfrq8bW5hL-EXJos130_assertion description "[PECAM-1 expression has been reported on a variety of human malignancies-especially hematopoietic and vascular cell cancers-but the significance of this expression has not been fully explored.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223274.RArnLWIPQJh7WYcCUsbIuXC_y_XtYPfrq8bW5hL-EXJos130_provenance.
- NP223287.RAqNjw3rt1ZyKBbDSBs068OAUN1Z9BxA1mPYQBDClpdYw130_assertion description "[The most common inherited form of PTD is associated with the DYT1 mutation on chromosome 9q34.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223287.RAqNjw3rt1ZyKBbDSBs068OAUN1Z9BxA1mPYQBDClpdYw130_provenance.
- NP223289.RAnSDQQhzx9VF0lXhb069G2E58WsbcYqmkl5HNmqEH7pI130_assertion description "[We found that TM4SF5 overexpression correlates with vascular endothelial growth factor (VEGF) expression in SNU449 hepatocytes and with vessel formation in clinical hepatocarcinoma samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223289.RAnSDQQhzx9VF0lXhb069G2E58WsbcYqmkl5HNmqEH7pI130_provenance.
- NP223300.RAtUU2Ui39J9Ua9PMdN6nvQeMV1ROkJjhd3F3m2tL6-3s130_assertion description "[The loss of CD81 is associated with differentiation and metastasis of HCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223300.RAtUU2Ui39J9Ua9PMdN6nvQeMV1ROkJjhd3F3m2tL6-3s130_provenance.
- NP223306.RAkD2sT0-R3fB14em4voaGFDo3RLgOsmiqtRHUxCuY3X0130_assertion description "[Association study of polymorphisms in the GluR6 kainate receptor gene (GRIK2) with schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223306.RAkD2sT0-R3fB14em4voaGFDo3RLgOsmiqtRHUxCuY3X0130_provenance.
- NP223307.RAqKe3R-pgaV4guwP1nRUSLOF9JZJoWlORAvngeXRML8E130_assertion description "[Breast cancers are known to frequently (over)express several well-characterized tumor-associated antigens (TAAs) such as carcinoembryonic antigen, MUC-1, Her-2/neu, and cancer/testis antigens such as NY-ESO-1, SSX-2, and members of the MAGE family.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223307.RAqKe3R-pgaV4guwP1nRUSLOF9JZJoWlORAvngeXRML8E130_provenance.
- NP223310.RAm5UC-3uFYj3VplTtlsihc3KeTWmCUWMkxfwn9FIBMb8130_assertion description "[In the present paper, we examined the incidence of polymorphic genes involved with the detoxification of exogenous chemicals, including carcinogens, namely GSTT1 (glutathione transferase theta1), GSTM1 (glutathione transferase micro1) and NQO1 (NAD(P)H:quinone oxidoreductase 1) in 60 Filipino paediatric patients with ALL (acute lymphoblastic leukaemia).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223310.RAm5UC-3uFYj3VplTtlsihc3KeTWmCUWMkxfwn9FIBMb8130_provenance.
- NP223312.RAkwc5pFdKyXjlyeHDMh8Q7Rnxp3m3JFLyb_RO44mCryU130_assertion description "[We report a case of chronic eosinophilic leukemia (CEL), demonstrating for the first time: (i) the association of CEL with the 5'KIAA1509/3'PDGFRB fusion gene as a consequence of a t(5;14)(q33;q32); (ii) the molecular detection of this rearrangement in an extramedullary site; (iii) the cloning and sequencing of the KIAA1509 and PDGFRB genomic breakpoints.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223312.RAkwc5pFdKyXjlyeHDMh8Q7Rnxp3m3JFLyb_RO44mCryU130_provenance.
- NP223316.RAp9p6SvRB8jlHRDKWkgjUVYbr30D3F_xxwKXI6R3b8DM130_assertion description "[The frequencies of polymorphisms in p53 and in MDM2 SNP309 did not differ from rates previously reported for normal control populations, and no polymorphism in either gene could be associated with early onset CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223316.RAp9p6SvRB8jlHRDKWkgjUVYbr30D3F_xxwKXI6R3b8DM130_provenance.
- NP223317.RAtCKdrFaex5Hz231ldtC05YhwkWgegXuUC53rAXTw-no130_assertion description "[Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223317.RAtCKdrFaex5Hz231ldtC05YhwkWgegXuUC53rAXTw-no130_provenance.
- NP223321.RAsDnCsP-hM2Ln5VBUVkAgAZ4Gg1EMjTZFGEB_2acFEi0130_assertion description "[Given the documented importance of IRS-1 and -2 in insulin signalling and the implications of distribution of these genes for the pathogenesis of insulin resistance and diabetes, we decided that the most recently identified member of the IRS family, IRS-4, was a relevant candidate to examine for genetic variability which might be associated with subsets of diabetes or insulin resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223321.RAsDnCsP-hM2Ln5VBUVkAgAZ4Gg1EMjTZFGEB_2acFEi0130_provenance.
- NP223329.RAk4RiU7wDHRP4aeYKah0eLUxxfliUn4csHxHi_fmKaeA130_assertion description "[We have therefore screened the TERT gene for mutation by denaturing HPLC in 80 patients with inherited and acquired bone marrow failure (24 with dyskeratosis congenita, 36 with constitutional aplastic anemia, 13 with idiopathic aplastic anemia and 7 with other forms of bone marrow failure).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223329.RAk4RiU7wDHRP4aeYKah0eLUxxfliUn4csHxHi_fmKaeA130_provenance.
- NP223336.RAp3kyombrCtnF7_OwrCTlLKRQ4Jelk_7kj4-hFe0hRL4130_assertion description "[Biallelic alterations of both ETV6 and CDKN1B genes in a t(12;21) childhood acute lymphoblastic leukemia case.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP223336.RAp3kyombrCtnF7_OwrCTlLKRQ4Jelk_7kj4-hFe0hRL4130_provenance.