Nanopublications

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NP283431.RAefIfTevNNPBUGW1I3wyW4qJimRfTIDnp9EJXFZbxUyI130_assertion description "[Recently, a poor anticoagulant response to activated protein C (APC), due to a mutation of factor V (FV Leiden), has been identified as the most frequent hereditary disorder associated with venous thrombophilia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283431.RAefIfTevNNPBUGW1I3wyW4qJimRfTIDnp9EJXFZbxUyI130_provenance.
NP283433.RASYz5hGJvXe580rWe8TcxCxkTXAm5JdV3coPtfF9lR4s130_assertion description "[In contrast, EVI-1 is barely expressed in normal hematopoietic cells, but it is overexpressed in chronic myelocytic leukemia in blastic crisis and myelodysplastic syndrome-derived leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283433.RASYz5hGJvXe580rWe8TcxCxkTXAm5JdV3coPtfF9lR4s130_provenance.
NP283434.RATqjPwP5z6TYjFSs8M1jL9etJtMgvKtpuyWLJ3Nku9qk130_assertion description "[The induction of PAI-1 and TF, and the decrease in u-PA expression in the kidneys of lupus-prone or of endotoxemic mice may promote the formation of renal microthrombi and thus contribute to the progression of renal damage in these models.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283434.RATqjPwP5z6TYjFSs8M1jL9etJtMgvKtpuyWLJ3Nku9qk130_provenance.
NP283438.RAbXnXAyrNek6mfosaZX08NwP1H0FYWvcpdb9i2lBPMFA130_assertion description "[The generated expandable reference map of SRM assays for cancer-associated proteins will be a valuable resource for accelerating and planning biomarker verification studies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283438.RAbXnXAyrNek6mfosaZX08NwP1H0FYWvcpdb9i2lBPMFA130_provenance.
NP283442.RAVbKyFi7q23XUKDrXQnzbbFQNzYv4TuBVoGDUeViCoBI130_assertion description "[Inhibition of hepatocarcinoma and tumor metastasis to liver by gene therapy with recombinant CBD-HepII polypeptide of fibronectin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283442.RAVbKyFi7q23XUKDrXQnzbbFQNzYv4TuBVoGDUeViCoBI130_provenance.
NP283448.RAZoYzq48hXH3pgyjP--Vh7U-mhZrlKzbRWKfgB0OoeiU130_assertion description "[NOTCH1 point mutations, insertions, and deletions producing aberrant increases in NOTCH1 signaling are frequently present in both childhood and adult T cell acute lymphoblastic leukemia/lymphoma and are detected in tumors from all major molecular subtypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283448.RAZoYzq48hXH3pgyjP--Vh7U-mhZrlKzbRWKfgB0OoeiU130_provenance.
NP283449.RAeSnifRC3bK0ZTQ8V21FVpv12DUZWLViZy8v5du0JygQ130_assertion description "[As PAX8/PPARG and RET/PTC rearrangements have been detected in follicular thyroid carcinomas (FTCs) and papillary thyroid carcinomas (PTCs), their detection in FNA smears could improve the FNA diagnosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283449.RAeSnifRC3bK0ZTQ8V21FVpv12DUZWLViZy8v5du0JygQ130_provenance.
NP283450.RAZf97pspLstoCIRtG92Up3kj9tQpt4b3Xe8rng3RomXc130_assertion description "[The autoantigens of Type 1A diabetes may be divided into subgroups based on their tissue distributions: Beta-cell-specific antigens like insulin, insulin derivatives, and IGRP (Islet-specific Glucose-6-phosphatase catalytic subunit Related Peptide); neurendocrine antigens such as carboxypeptidase H, insulinoma-associated antigen (IA-2), glutamic acid decarboxylase (GAD65), and carboxypeptidase E; and those expressed ubiquitously like heat shock protein 60 (a putative autoantigen for type 1 diabetes).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283450.RAZf97pspLstoCIRtG92Up3kj9tQpt4b3Xe8rng3RomXc130_provenance.
NP283452.RAes65vjq_0EZ_IhzJqkND8g3DTF1hCgmRYUud9FoG4PU130_assertion description "[The gene expression microarray and ontology analysis revealed that genes involved in mitotic processes, including AURKA, were associated with poor prognosis in glioblastoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283452.RAes65vjq_0EZ_IhzJqkND8g3DTF1hCgmRYUud9FoG4PU130_provenance.
NP283453.RATW-bZ_gOeRACWN6OcOilPXpizFTu5o5U5Bb0LDaWyC8130_assertion description "[NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283453.RATW-bZ_gOeRACWN6OcOilPXpizFTu5o5U5Bb0LDaWyC8130_provenance.
NP283456.RATigDc7CCMGQAQ1ila6CC5U-QNu5CInHD9FUFJGmdYu4130_assertion description "[A nonverbal learning disability in a case of central hypoventilation syndrome without a PHOX2B gene mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283456.RATigDc7CCMGQAQ1ila6CC5U-QNu5CInHD9FUFJGmdYu4130_provenance.
NP283466.RAR6LJQR5f-qY7_2Qar7IbUJC-gbIjs2nykKmZ5V1BgsU130_assertion description "[Consequently, heparanase expression is considered a biomarker for cancer detection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283466.RAR6LJQR5f-qY7_2Qar7IbUJC-gbIjs2nykKmZ5V1BgsU130_provenance.
NP283479.RARgURieWZ3reeNP56NO6q7-RLkK_BxOez2-CccoVuPzw130_assertion description "[Together, these results firstly demonstrated that Mac-2BP can be used as a therapeutic target and potential biomarker for lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283479.RARgURieWZ3reeNP56NO6q7-RLkK_BxOez2-CccoVuPzw130_provenance.
NP283480.RAewJOBLhcwyCSsmI7lyf125SxqSb1O2YJi2U_eM0kXbk130_assertion description "[Compared with the NAT, expression of let-7 was significantly lower in ESCC tissues (P < 0.05), and there was a significant correlation between low expression of let-7 and lymph node metastasis in ESCC (P < 0.05).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283480.RAewJOBLhcwyCSsmI7lyf125SxqSb1O2YJi2U_eM0kXbk130_provenance.
NP283483.RAdjx8VTDCRHec2nRBsjgpAACmX-ryXh1dtWFJrW-fJMY130_assertion description "[Thyrotropin receptor epitopes and their relation to histocompatibility leukocyte antigen-DR molecules in Graves' disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283483.RAdjx8VTDCRHec2nRBsjgpAACmX-ryXh1dtWFJrW-fJMY130_provenance.
NP283485.RAaHeUE2zEnAM5RXtqmP0MECy3cNr4cObN31BzzF8OK5s130_assertion description "[Genetic analysis showed that the PCK rat model is orthologous to autosomal recessive polycystic kidney disease, and allowed the human gene, PKHD1, to be precisely localized and identified.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283485.RAaHeUE2zEnAM5RXtqmP0MECy3cNr4cObN31BzzF8OK5s130_provenance.
NP283490.RAem3oQHkJe_VRBmV0xIFEof2donl6hmtlaG2N7cCII-g130_assertion description "[Tumor migration/invasion is the main cause of tumor progression and STAT3 is needed to enhance tumor migration/invasion by up-regulating MMP-9.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283490.RAem3oQHkJe_VRBmV0xIFEof2donl6hmtlaG2N7cCII-g130_provenance.
NP283491.RATwH-Q_u7wz1Al8URnaf6NLW39E2WKAJYRskXIS4n31o130_assertion description "[Endogenous expression of transcripts for NPY2R, IRF1, and SNAI1 was documented in neuroendocrine cells, and the NPY2R mRNA was differentially expressed in two neuroendocrine tissues (adrenal gland, brainstem) of a rodent model of hypertension and the metabolic syndrome, the spontaneously hypertensive rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283491.RATwH-Q_u7wz1Al8URnaf6NLW39E2WKAJYRskXIS4n31o130_provenance.
NP283493.RAQ9WzcTpheNzV3C6PtWVVnYq-IMZ78Lmpau0qFTE9co0130_assertion description "[Transient expression of the fsL178, L261X, and M382I mutations in COS-1 cells demonstrated that these lesions did not produce catalytically active ASM, consistent with the severe neuronopathic Type A NPD phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283493.RAQ9WzcTpheNzV3C6PtWVVnYq-IMZ78Lmpau0qFTE9co0130_provenance.
NP283503.RARBbiwptE7v5dXcYwU7aSRF-vExkmaO_Ouet5-CWn_C0130_assertion description "[Our mutation and expression analysis in neuroblastoma cell lines, combined with expression analysis in normal tissues, putative function and prior implication in neuroblastoma pathogenesis, suggests that the most promising TSG deleted from the 1p36 SRD is CHD5, but TNFRSF25, CAMTA1 and AJAP1 are also viable candidates.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283503.RARBbiwptE7v5dXcYwU7aSRF-vExkmaO_Ouet5-CWn_C0130_provenance.
NP283509.RAR6ePOO-V5kAJxZjuLTodI4qNP9dsFGWD6WfEjweVL1w130_assertion description "[None of these RAVER2 SNPs were associated with CD and APS susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283509.RAR6ePOO-V5kAJxZjuLTodI4qNP9dsFGWD6WfEjweVL1w130_provenance.
NP283514.RAaQxwzRP5hUsbTRs1l5-Qg-AJ3z1RO1G-XwQdaOl5Pgc130_assertion description "[Recurrent grade 2 astrocytomas and grade 2 or 3 oligodendrogliomas showed higher levels of HES6 immunoreactivity than the corresponding primary tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283514.RAaQxwzRP5hUsbTRs1l5-Qg-AJ3z1RO1G-XwQdaOl5Pgc130_provenance.
NP283515.RAWoSh_1FvcZeNroLadeo1PyvwxnZwbWSzGMY9l9zVUFk130_assertion description "[Mutations in the LDLr gene (LDLR), which is located on chromosome 19, cause familial hypercholesterolemia (FH), an autosomal dominant disorder characterized by severe hypercholesterolemia associated with premature coronary atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283515.RAWoSh_1FvcZeNroLadeo1PyvwxnZwbWSzGMY9l9zVUFk130_provenance.
NP283517.RAWjvJx-ZZYAVTpzFckajdJrkjvNNAz-v6LhEhbS7UDZY130_assertion description "[All patients underwent blood tests, assessment of homocysteine, vitamin B(12), folate, hepatitis C virus (HCV)-RNA levels, screening for MTHFR gene polymorphisms and liver ultrasound examination.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283517.RAWjvJx-ZZYAVTpzFckajdJrkjvNNAz-v6LhEhbS7UDZY130_provenance.
NP283526.RAZsS5k4LRH1tjWaEjaocZkFR9mWkMoG0B42Thb7n5W0A130_assertion description "[The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283526.RAZsS5k4LRH1tjWaEjaocZkFR9mWkMoG0B42Thb7n5W0A130_provenance.
NP283536.RAWSPnfflItIL0t9hpwOsNxHtkv9h_nsuHNfcTHww03w0130_assertion description "[However, a major problem in such FCM analyses of solid tumor samples is the admixture of tumor cells with normal epithelial, stromal, and inflammatory cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283536.RAWSPnfflItIL0t9hpwOsNxHtkv9h_nsuHNfcTHww03w0130_provenance.
NP283537.RAfiyXjS50kxG6Rg0-pwuoifxPDwSCY8sl5nLv7mgfDHc130_assertion description "[Our preliminary results show that KLK14 is down-regulated, at the mRNA level, in breast, testicular, prostatic, and ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283537.RAfiyXjS50kxG6Rg0-pwuoifxPDwSCY8sl5nLv7mgfDHc130_provenance.
NP283540.RAZtFwO50AMAXuTqvQ5Yu5LIpSr90Jj5umcu_VMtIFxwA130_assertion description "[Detection of RET/PTC, TRK and BRAF mutations in preoperative diagnosis of thyroid nodules with indeterminate cytological findings.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283540.RAZtFwO50AMAXuTqvQ5Yu5LIpSr90Jj5umcu_VMtIFxwA130_provenance.
NP283544.RATusVFIYbGVhsXHcqlMGU0R9HLzoNrNxRHdOZR54MUAc130_assertion description "[Therefore, the pseudoautosomal region 1 (PAR1) of 80 patients with LWD, in whom SHOX deletions and mutations had been excluded, was screened for deletions by use of a new panel of microsatellite markers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283544.RATusVFIYbGVhsXHcqlMGU0R9HLzoNrNxRHdOZR54MUAc130_provenance.
NP283550.RAX2_i4XJIosiO0Iub3VB0d3l49_NHEYXcHA_8RQdGN48130_assertion description "[To comprehensively examine the cancer risk and tumour spectrum in Finnish FH mutation positive families, genealogical and cancer data were obtained from 868 individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283550.RAX2_i4XJIosiO0Iub3VB0d3l49_NHEYXcHA_8RQdGN48130_provenance.
NP283551.RAbeMsQ8PoCu-JrXeSBFRCtpqn9utX0xsSSERqOVkj1Y4130_assertion description "[Gastric specimens were obtained for H. pylori status and cytokine evaluation and blood samples for determination of iron deficiency/iron deficiency anaemia parameters and IL1 cluster and TNFA polymorphisms that are associated with increased cytokine secretions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283551.RAbeMsQ8PoCu-JrXeSBFRCtpqn9utX0xsSSERqOVkj1Y4130_provenance.
NP283556.RAfpfEhZCWx6VacE6NGGgAF-HqDHVyGT17bFEE70VQcK4130_assertion description "[The specificity of this assay was evaluated using 4 reference strains of Mycobacterium tuberculosis complex (MTC), 22 species of non-tuberculous mycobacteria (NTM), 7 non-mycobacterial species, and 50 clinical M. tuberculosis isolates.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283556.RAfpfEhZCWx6VacE6NGGgAF-HqDHVyGT17bFEE70VQcK4130_provenance.
NP283557.RAcd4dUcYEhHHFCQOmiaQQ9V3NJs3p8sKD5zC4M-L7Xe8130_assertion description "[Moreover, this study demonstrates gene regulations corresponding to the ATC or PTC phenotypes like inflammatory reaction, epithelial to mesenchymal transition (EMT) and invasion, high proliferation rate, dedifferentiation, calcification and fibrosis processes, high glucose metabolism and glycolysis, lactate generation and chemoresistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283557.RAcd4dUcYEhHHFCQOmiaQQ9V3NJs3p8sKD5zC4M-L7Xe8130_provenance.
NP283559.RAVOiBGuvDf2QuBiaYb78h1Gx1RQD-x1i9Q51BbzrMXmU130_assertion description "[We report here the lack of CD40L expression in four unrelated male children with the hyper-IgM syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283559.RAVOiBGuvDf2QuBiaYb78h1Gx1RQD-x1i9Q51BbzrMXmU130_provenance.
NP283560.RAdcrTCWhemGIjA6iI6Iulaxg3LRKHbOL6ShUGGGgWdXY130_assertion description "[Nonhematologic malignancies included colon (2), lung (2), thyroid (2), and prostate cancer (1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283560.RAdcrTCWhemGIjA6iI6Iulaxg3LRKHbOL6ShUGGGgWdXY130_provenance.
NP283562.RAenA1TfAuwIHogUS-S7c7jcJvttxDMmkRWTMLiVINiUc130_assertion description "[Compared to controls and 354 background/alignment markers, AD brain showed a generalized depression in brain gene transcription, including decreases in RNA encoding transcription factors (TFs), neurotrophic factors, signaling elements involved in synaptic plasticity such as synaptophysin, metallothionein III, and metal regulatory factor-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283562.RAenA1TfAuwIHogUS-S7c7jcJvttxDMmkRWTMLiVINiUc130_provenance.
NP283564.RAfFLsIN30XFHG0XxltGwLDjvVEEmbJ_mlbtMClWCqSYo130_assertion description "[This review highlights some of the major findings, the roles and problems associated with MDR-linked ABC drug transporters in metastatic cancers and solid tumors, and the current strategies to improve the clinical outcome in cancer chemotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283564.RAfFLsIN30XFHG0XxltGwLDjvVEEmbJ_mlbtMClWCqSYo130_provenance.
NP283565.RAanBNiuViXuhBz8dfgXKJ3r9PD9zZIROFzfJaPMrshN8130_assertion description "[JAK2 and MPL mutations were detected in circulating granulocytes and bone marrow CD34+ cells, but not in T lymphocytes, from 11 of 19 patients with RARS-T. Three patients with RARS, who initially had low to normal platelet counts, progressed to RARS-T, and 2 of them acquired JAK2 (V617F) at this time.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283565.RAanBNiuViXuhBz8dfgXKJ3r9PD9zZIROFzfJaPMrshN8130_provenance.
NP283572.RAVivNAbCYfWZzm-LEhNhBzrkfhreXV7WOlAiI5GUSnzE130_assertion description "[Four of the PARK genes, SNCA at PARK1, UCH-L1 at PARK5, PINK1 at PARK6 and LRRK2 at PARK8, have been implicated in sporadic PD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283572.RAVivNAbCYfWZzm-LEhNhBzrkfhreXV7WOlAiI5GUSnzE130_provenance.
NP283574.RAcTMsiHIxmRXnotX-WAYevBIAdwrx8JkRXe8RABoICjk130_assertion description "[Gene polymorphisms of TGF-β1 in 869T > C and PAI-1 4G/5G may affect the susceptibility to IPF in Han ethnicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283574.RAcTMsiHIxmRXnotX-WAYevBIAdwrx8JkRXe8RABoICjk130_provenance.
NP283577.RAQ-Rb2nbKkSoEEdyiVoH7F3Qr0gLnO63sOUsLo7ECdyc130_assertion description "[Consistently, these leukaemias show lower frequencies of prototypical T-ALL lesions such as CDKN2A/B deletions and activating mutations in NOTCH1 and show a higher prevalence of mutations typically associated with the pathogenesis of acute myeloid leukaemias (AMLs).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283577.RAQ-Rb2nbKkSoEEdyiVoH7F3Qr0gLnO63sOUsLo7ECdyc130_provenance.
NP283579.RAZCySpWHm_5DGwmpn6oajvCifqd08Jd-8-eUuSbvvLQk130_assertion description "[To examine whether the G-to-A polymorphism at position -308 in the promoter of the tumour necrosis factor-alpha (TNFalpha) gene influences the therapeutic response to TNFalpha-blockers in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283579.RAZCySpWHm_5DGwmpn6oajvCifqd08Jd-8-eUuSbvvLQk130_provenance.
NP283580.RARizdR9VtDkpmdRbOdSRNxNdaTHFR7Y97Uq2A44zNyyk130_assertion description "[This study tested for an association between SLC18A2 and ADRB1 and treatment outcome in 873 major depressive disorder patients treated with the antidepressant citalopram in the Sequenced Treatment Alternatives to Relieve Depression study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283580.RARizdR9VtDkpmdRbOdSRNxNdaTHFR7Y97Uq2A44zNyyk130_provenance.
NP283582.RAWyyWVzLjABXTOKT8kT5da6jRF7_Nn6-cxkAxXEFgegk130_assertion description "[Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behavioral correction of a rat model of Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283582.RAWyyWVzLjABXTOKT8kT5da6jRF7_Nn6-cxkAxXEFgegk130_provenance.
NP283588.RAfWpwDrr1PH5rveM7bJSzJO49oGF1mfMrxEEBhE04nuY130_assertion description "[In this study, we determined the level of expression of EGFR and the mutational status of the EGFR receptor in a subset of osteosarcoma tumor samples as well as in a series of established bone tumor-derived cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283588.RAfWpwDrr1PH5rveM7bJSzJO49oGF1mfMrxEEBhE04nuY130_provenance.
NP283590.RAeYK3gng8VMzoGZP8EPIZTFocmYEY5Bt4zCjgAPIMgi8130_assertion description "[We studied the expression of vitamin D receptor (VDR) and related enzymes, including 1,25(OH)(2)D-24-hydroxylase (24-OHase; CYP24A1) and 25(OH)D-1α-hydroxylase (CYP27B1), in CNS tissues of 39 MS patients and 20 controls and in primary human glial cells in vitro.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283590.RAeYK3gng8VMzoGZP8EPIZTFocmYEY5Bt4zCjgAPIMgi8130_provenance.
NP283595.RAfOXYe-Ozg3_v66PSN348TapWQmgQ9P1X5DmQfFEfGwc130_assertion description "[Promoter hypermethylation of DAP-kinase has been observed in a high variety of primary tumors including head and neck tumors, and non-small cell lung cancers, where an association with poor prognosis was also noted.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283595.RAfOXYe-Ozg3_v66PSN348TapWQmgQ9P1X5DmQfFEfGwc130_provenance.
NP283597.RAZS2vHm2ahpFS_8q49dqYVwk4fBVuoUb238Ph29SDPJk130_assertion description "[Apoptin, a small protein encoded by chicken anemia virus (CAV) was expressed in various human hematologic malignant cell lines derived from leukemias and lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283597.RAZS2vHm2ahpFS_8q49dqYVwk4fBVuoUb238Ph29SDPJk130_provenance.
NP283599.RAQeuO1VDYxluGjEbGNGY2l-V_CI26aVInsUzT4gUVC6o130_assertion description "[In conclusion, we observed an interaction of A1166C AT1R polymorphism with diabetes in men but not of I/D ACE and M235T AGT polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283599.RAQeuO1VDYxluGjEbGNGY2l-V_CI26aVInsUzT4gUVC6o130_provenance.
NP283600.RAaSDWxJx2259k2r0GM9v0by6St--fsZ5QlUiQUHbfW6o130_assertion description "[Primary hyperparathyroidism (HPT), most commonly due to parathyroid adenoma, is a disorder characterized by excessive secretion of PTH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283600.RAaSDWxJx2259k2r0GM9v0by6St--fsZ5QlUiQUHbfW6o130_provenance.
NP283605.RAQiTLzgPQpyIvkLv6h1yKpJTkVkpq75D4ZdrkbaJKdO8130_assertion description "[We also found elevated levels of the TLR4 adaptor protein TRIF and reduced levels of the TLR4-inhibitor SIGIRR in the patients with ABU, but MyD88 and TRAM levels were not significantly altered.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283605.RAQiTLzgPQpyIvkLv6h1yKpJTkVkpq75D4ZdrkbaJKdO8130_provenance.
NP283613.RAS6O3WNy9cIflb7_ubkNTjWCVF4A0Qi6fUk04MQeVuX4130_assertion description "[Gastric (AGS, MKN28) and esophageal (FLO-1) adenocarcinoma cancer cell lines that lack t-DARPP expression were utilized to establish stable and transient in vitro expression models of t-DARPP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283613.RAS6O3WNy9cIflb7_ubkNTjWCVF4A0Qi6fUk04MQeVuX4130_provenance.
NP283617.RAeb-heSWKvYqGKomX5Gr7DmsIpBDWpL1fXfPXZHFCK6s130_assertion description "[The gene mutated in families displaying the `incomplete phenotype` of CSNB (i.e., CSNB2) has recently been identified.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283617.RAeb-heSWKvYqGKomX5Gr7DmsIpBDWpL1fXfPXZHFCK6s130_provenance.
NP283623.RAVEjQwz5fU-2_AYGqHkoxBYIax1TZWEclF9QXew8G-As130_assertion description "[Autosomal dominant optic atrophy (ADOA, OMIM 165500), an inherited optic neuropathy that leads to retinal ganglion cell degeneration and reduced visual acuity during the early decades of life, is mainly associated with mutations in the OPA1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283623.RAVEjQwz5fU-2_AYGqHkoxBYIax1TZWEclF9QXew8G-As130_provenance.
NP283625.RAdFhKpOJktmfp2q2WRSS7Y0SKrT9XdfeApI-Aa3v1v8U130_assertion description "[Renal involvement is among its most common extra hepatic manifestations and usually manifests in the form of immune complex mediated glomerulopathy, such as membranous glomerulonephritis (MGN), membranoproliferative glomerulonephritis (MPGN), mesangioproliferative glomerulonephritis and immunoglobulin A (IgA) nephropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283625.RAdFhKpOJktmfp2q2WRSS7Y0SKrT9XdfeApI-Aa3v1v8U130_provenance.
NP283628.RAbqkf2F7oRLTw1L7qTUW8MBGRAbNEL_dvALYVYuf8EIk130_assertion description "[Recent studies have demonstrated that although SFT expression is reciprocally regulated in response to cellular iron levels, it is aberrantly upregulated in the liver of hemochromatosis patients, indicating that enhanced SFT expression contributes to the etiology of this disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283628.RAbqkf2F7oRLTw1L7qTUW8MBGRAbNEL_dvALYVYuf8EIk130_provenance.
NP283629.RAa9yyIqeM-ZHzn9OhfnuO7hoTXBDYaGzTH60IItpmWCI130_assertion description "[For severe asthma multiple regression analysis revealed as independent risk factors IL-17 (p = 0.000290), NSAID intolerance (p = 0.000585) and low FEV(1) (p = 0.000059).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283629.RAa9yyIqeM-ZHzn9OhfnuO7hoTXBDYaGzTH60IItpmWCI130_provenance.
NP283639.RAe8HnqqerQfwoOt6IIvIEd2IXqRBItn4MgteB-MRPb8c130_assertion description "[To determine the location of a putative tumor suppressor gene (TSG), and evaluate the frequency loss of heterozygosity (LOH) of the long arm of chromosome 9 (9q) in bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283639.RAe8HnqqerQfwoOt6IIvIEd2IXqRBItn4MgteB-MRPb8c130_provenance.
NP283642.RAfr-weO0FhCOkEbwQhljfQxuRXPXObCYdycHeRlDLk_k130_assertion description "[The clinical implications of MMP-11 and CK-20 expression in human breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283642.RAfr-weO0FhCOkEbwQhljfQxuRXPXObCYdycHeRlDLk_k130_provenance.
NP283646.RAcVP_rCpf94zteoYTg5n_qupa_JzYB9oNxD9rrfwd8Z8130_assertion description "[These results suggest that the p73 G4C14-to-A4T14 polymorphism does not significantly affect susceptibility to lung cancer in the Korean population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283646.RAcVP_rCpf94zteoYTg5n_qupa_JzYB9oNxD9rrfwd8Z8130_provenance.
NP283650.RARrL-VXQPnE7_ri6j8DSfik6IA4dkPl-qWg1rUEhGRLk130_assertion description "[Of those, syndromic deafness-associated tRNA mutations such as tRNA(Leu(UUR)) 3243A>G are often present in heteroplasmy, while non-syndromic deafness-associated tRNA mutations including tRNA(Ser(UCN)) 7445A>G often occur in homplasmy or in high levels of heteroplasmy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283650.RARrL-VXQPnE7_ri6j8DSfik6IA4dkPl-qWg1rUEhGRLk130_provenance.
NP283656.RAQOS7Gvt32Ca0kRgi5C73UUCa4e_aBZWfc2PiJS-IAU0130_assertion description "[MDM2/p53 pathway plays an important role in the control of apoptotic and proliferation mechanisms, and alterations in this pathway have been described in myelodysplastic syndromes (MDS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283656.RAQOS7Gvt32Ca0kRgi5C73UUCa4e_aBZWfc2PiJS-IAU0130_provenance.
NP283658.RATpcot5ggOqjqCZvo2t8x54LvtdQF2jwH1WanqFf9i48130_assertion description "[Although these nonsteroidal anti-inflammatory drugs (NSAIDs) are often associated with gastrointestinal toxicity, there is renewed interest in their use as colorectal cancer (CRC) chemopreventive agents due to the adverse side effects associated with long-term use of selective COX-2 inhibitors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283658.RATpcot5ggOqjqCZvo2t8x54LvtdQF2jwH1WanqFf9i48130_provenance.
NP283660.RAcI_unWmM6kVnJA9UDYY0OSf-D014dzX0MPLmkgPMejs130_assertion description "[In 35 patients with normal karyotype and 16 patients with cytogenetic anomalies not presently associated with FAB subtypes the expected correlations of rather immature myeloid immunologic phenotypes with M1 and M2 morphology and CD14 expression in monoblastic leukemias was found.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283660.RAcI_unWmM6kVnJA9UDYY0OSf-D014dzX0MPLmkgPMejs130_provenance.
NP283664.RAbxsa1_fQTOpMYvq9CD7C7sSJqa34wIzjInyjubolqf0130_assertion description "[Down regulation of TGFbeta-1 gene transcription was related to the occurrence of infection but not the onset of sepsis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283664.RAbxsa1_fQTOpMYvq9CD7C7sSJqa34wIzjInyjubolqf0130_provenance.
NP283665.RAV0NiZQBhI4xRzTwkWMp46-JdiLMzqFpI4eCbFOaMyOA130_assertion description "[Our results indicate that variations in APOB48R and nearby genes are among the many factors involved in hypercholesterolemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283665.RAV0NiZQBhI4xRzTwkWMp46-JdiLMzqFpI4eCbFOaMyOA130_provenance.
NP283667.RAVP6Rf_3rJsJ6_UVYh4I11lM3C7DJ3auHmu8HfayI4jQ130_assertion description "[We have examined the impact of tumor size, histologic grade, estrogen receptor (ER) status, tumor ploidy, and S-phase fraction (SPF) on relapse-free survival (RFS) for 169 patients with node-negative breast cancer in order to identify groups of patients at high and low risk of relapse.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283667.RAVP6Rf_3rJsJ6_UVYh4I11lM3C7DJ3auHmu8HfayI4jQ130_provenance.
NP283681.RAa8LG1MuP_gt-x9sXNYtjUXRhbY_H9Vi8SJ_Zelj10EQ130_assertion description "[At the protein level, expression of the immunohistochemical markers cytokeratins (pan-cytokeratin staining), placental-like alkaline phosphatase, anti-cytokeratin clone 5.2, CD30, anion exchanger 1/3, junction plakoglobulin (JUP), and POU domain, class 5, transcription factor 1 (octomer-binding transcription factor 3/4) was significantly different between seminomas and embryonal tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283681.RAa8LG1MuP_gt-x9sXNYtjUXRhbY_H9Vi8SJ_Zelj10EQ130_provenance.
NP283684.RAcD-D9oLJ6Ip1m65NPAWYo6fwv96EMEOqTexFK8TW1EE130_assertion description "[Translocation between the BCL-2 and immunoglobulin heavy chain genes is detected in 85% to 90% of all follicular lymphomas in whites.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283684.RAcD-D9oLJ6Ip1m65NPAWYo6fwv96EMEOqTexFK8TW1EE130_provenance.
NP283685.RAQ2U1q31R81FwWa4OWGfBeSZpOefHW2yzx2zz0s0kBIk130_assertion description "[Human papillomavirus infection along with p53 expression plays a yet to be defined role in the pathogenesis of a limited number of cases of proliferative verrucous leukoplakia and squamous cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283685.RAQ2U1q31R81FwWa4OWGfBeSZpOefHW2yzx2zz0s0kBIk130_provenance.
NP283687.RAVlcOcdM_2eQJp1craiF0hfGVX5VCcGDDKtg79P9cxn8130_assertion description "[Supporting evidence includes the following: [1] expression of constitutive COX-2-catalyzed prostaglandin biosynthesis is induced by most cancer-causing agents including tobacco smoke and its components (polycylic aromatic amines, heterocyclic amines, nitrosamines), essential polyunsaturated fatty acids (unconjugated linoleic acid), mitogens, growth factors, proinflammatory cytokines, microbial agents, tumor promoters, and other epigenetic factors, [2] COX-2 expression is a characteristic feature of all premalignant neoplasms, [3] COX-2 expression is a characteristic feature of all malignant neoplasms, and expression intensifies with stage at detection and cancer progression and metastasis, [4] all essential features of carcinogenesis (mutagenesis, mitogenesis, angiogenesis, reduced apoptosis, metastasis, and immunosuppression) are linked to COX-2-driven prostaglandin (PGE-2) biosynthesis, [5] animal studies show that COX-2 up-regulation (in the absence of genetic mutations) is sufficient to stimulate the transformation of normal cells to invasive cancer and metastatic disease, [6] non-selective COX-2 inhibitors, such as aspirin and ibuprofen, reduce the risk of human cancer and precancerous lesions, and [7] selective COX-2 inhibitors, such as celecoxib, reduce the risk of human cancer and precancerous lesions at all anatomic sites thus far investigated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283687.RAVlcOcdM_2eQJp1craiF0hfGVX5VCcGDDKtg79P9cxn8130_provenance.
NP283689.RAe0aq-3oEqCnAc5mBAAsEvwm5VEWid2PJXVztXGhYJCA130_assertion description "[Genetic polymorphism of apolipoprotein A-IV in five different regions of Europe. Relations to plasma lipoproteins and to history of myocardial infarction: the EARS study. European Atherosclerosis Research Study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283689.RAe0aq-3oEqCnAc5mBAAsEvwm5VEWid2PJXVztXGhYJCA130_provenance.
NP283700.RAe_m5126VJmRnFtu_tg2wf4BRi4etS-KB4QlrMmanx04130_assertion description "[Cross-breeding of APOC1 mice on an apoE-deficient background resulted in a marked 55-fold increase in TG, confirming that the apoC-I-induced hyperlipidemia cannot merely be attributed to blockade of apoE-recognizing hepatic lipoprotein receptors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283700.RAe_m5126VJmRnFtu_tg2wf4BRi4etS-KB4QlrMmanx04130_provenance.
NP283701.RARA7Iu225k8AK8x3aXZnzncMdEniYsAKngZ5OVm1r8gY130_assertion description "[Based on our findings, CNGB3 should be considered as a candidate gene to be evaluated in patients with forms of cone dysfunction, including macular degeneration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283701.RARA7Iu225k8AK8x3aXZnzncMdEniYsAKngZ5OVm1r8gY130_provenance.
NP283703.RAdAOExLT3NNB2OAl53e4iuYp8g2dOlG-X2kynwXeFgeQ130_assertion description "[In summary, our study may explain the elevated levels of IL-21 and GzmB in SLE and other AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283703.RAdAOExLT3NNB2OAl53e4iuYp8g2dOlG-X2kynwXeFgeQ130_provenance.
NP283704.RAVZwZeTpe-EYg2WHL_GgFIrjWohUzt7UIcfCZrTG-_Aw130_assertion description "[Laboratory studies revealed the following values: FSH level 72.48 mIU/mL (normal women: <40 mIU/mL), LH level 32.87 mIU/mL (normal women: <21 mIU/mL), and E(2) level <20 pg/mL (normal women up to 375 pg/mL), confirming primary ovarian failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283704.RAVZwZeTpe-EYg2WHL_GgFIrjWohUzt7UIcfCZrTG-_Aw130_provenance.
NP283705.RAXfGEZwCUVTl1RaDmso9Cbd9ZIJbPMQzmJf_xXN-7My4130_assertion description "[Several biochemical pathways can lead to cancer cachexia, one of which involves the elevation of the cytokines, such as tumor necrosis factor alpha (TNF-alpha) and interferon gamma (INF-gamma).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283705.RAXfGEZwCUVTl1RaDmso9Cbd9ZIJbPMQzmJf_xXN-7My4130_provenance.
NP283707.RAYjH_a62tdHy1LpvFnhi969q6cVTrjcpTrEy97BDg74U130_assertion description "[Hu antigen R (HuR), a ubiquitously expressed protein, controls a range of cellular functions such as tumor progression, apoptosis, invasion, and metastasis by stabilizing the AU-rich element located at the 3'-untranslated region (UTR) of target mRNAs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283707.RAYjH_a62tdHy1LpvFnhi969q6cVTrjcpTrEy97BDg74U130_provenance.
NP283709.RAbrlH2em0_54IgJqIHvLvlai8dpHI27-ixIICwYhuBjI130_assertion description "[We expressed a chimeric protein (called His-ILFAC) consisting of the mature coding portion of gibbon interleukin-3 (IL-3) and full-length FAC in Escherichia coli.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283709.RAbrlH2em0_54IgJqIHvLvlai8dpHI27-ixIICwYhuBjI130_provenance.
NP283711.RAVV7evY3EytjOlurV4b0hMEVEMuS6qOWv15d-nDO7PqI130_assertion description "[The amplified sequences were analyzed using array-based CGH.These findings confirm that the NUP214-ABL1 gene requires amplification for oncogenicity; it is part of a multistep process of leukemogenesis; and it can be a late event present only in subpopulations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283711.RAVV7evY3EytjOlurV4b0hMEVEMuS6qOWv15d-nDO7PqI130_provenance.
NP283722.RAa2pRPUm9xzFuLqjnrpv7zmKH1zuzmr5W4rkSL-6RJLE130_assertion description "[Polymorphisms of HLA-A and HLA-B genes in genetic susceptibility to esophageal carcinoma in Chaoshan Han Chinese.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283722.RAa2pRPUm9xzFuLqjnrpv7zmKH1zuzmr5W4rkSL-6RJLE130_provenance.
NP283734.RAeAmrAG1JM5CDN5zeEM9pYIWDShpCXndA3e9AZjR0Z9A130_assertion description "[However, the ability of epigenetic drugs to stimulate metastasis in RMS cells was inhibited by expression of an Ezrin-specific shRNA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283734.RAeAmrAG1JM5CDN5zeEM9pYIWDShpCXndA3e9AZjR0Z9A130_provenance.
NP283735.RAWBQakZch3d3QoDQQPBbS0WyuZ9kt4AJFUpGbJFhFCgY130_assertion description "[In humans, PAX6, EOMES, and TBR1 have been linked to intellectual disability and autism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283735.RAWBQakZch3d3QoDQQPBbS0WyuZ9kt4AJFUpGbJFhFCgY130_provenance.
NP283736.RAV8RtxVCNDvidjtP1SLwTmqK_x9phhJF2zI3yO-QEJoI130_assertion description "[IL-10-592 AA genotype is not associated with either pathologic subtypes (intestinal or diffuse) or anatomic subtypes (non-cardia or cardia) of gastric cancer susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283736.RAV8RtxVCNDvidjtP1SLwTmqK_x9phhJF2zI3yO-QEJoI130_provenance.
NP283737.RAUbz2NhuwpdX26PE13pza_Res8_yhUQa8KrMpEmAdOnE130_assertion description "[Of the 12 subjects with LRP5 mutation six had diabetes and one had impaired glucose tolerance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283737.RAUbz2NhuwpdX26PE13pza_Res8_yhUQa8KrMpEmAdOnE130_provenance.
NP283741.RAR-s_wlAli_rcjVOD8FMUXAgGtBqAOf4Eiy9uTumZqrY130_assertion description "[Mutations in four other genes that encode known or putative glycosylation enzymes (POMT1, POMGnT1, fukutin and FKRP) are also associated with muscular dystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283741.RAR-s_wlAli_rcjVOD8FMUXAgGtBqAOf4Eiy9uTumZqrY130_provenance.
NP283746.RAaoB47UReFrzfbtlS2z2vw5uuTeaGX7I1dwmBL82wgvE130_assertion description "[An initial screen of gene expression data for 48 RTKs in 148 sarcomas showed that ROR2 was expressed in a subset of leiomyosarcoma (LMS), gastrointestinal stromal tumour (GIST) and desmoid-type fibromatosis (DTF).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283746.RAaoB47UReFrzfbtlS2z2vw5uuTeaGX7I1dwmBL82wgvE130_provenance.
NP283753.RAdgiU6j_7JFyzb_gC1mcQu2QH2_ELP7zAWAiVEf-LjiI130_assertion description "[Among the more-interesting information gained from these models is the finding that inhibition of a particular GRK - GRK2 or beta adrenergic receptor kinase 1 (betaARK1) - is a potential novel therapeutic strategy to improve function in the setting of heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283753.RAdgiU6j_7JFyzb_gC1mcQu2QH2_ELP7zAWAiVEf-LjiI130_provenance.
NP283756.RAdnaSHBaGVT8DCqslaFcPzCfF_mnvV2y_x-y_uDScglI130_assertion description "[USOD and SEDI immunohistochemistry of spinal cord sections from ALS cases resulting from SOD1 mutations (A4V and DeltaG27/P28) shows that inclusions within remaining motor neurons contain SOD1 with both an unfolded beta barrel and a disrupted dimer interface.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283756.RAdnaSHBaGVT8DCqslaFcPzCfF_mnvV2y_x-y_uDScglI130_provenance.
NP283758.RAQ1g8ITGlw00cxTAHf8rYjApcg7XQA0WLpuChKAfVBhw130_assertion description "[In a study of 130 Caucasian (n = 61) and African-American (n = 69) men with prostate cancer who underwent radical prostatectomy, we quantified polycyclic aromatic hydrocarbon (PAH)-DNA adducts in prostate tumor and adjacent nontumor cells by immunohistochemistry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283758.RAQ1g8ITGlw00cxTAHf8rYjApcg7XQA0WLpuChKAfVBhw130_provenance.
NP283762.RARe2Ckgd9y1Gb2JLkvR1BUWr1Su26eVFdS2eft0ayyDo130_assertion description "[Finally, the study of associations between critical clinicopathological parameters and activated DDR factors highlighted a statistically meaningful correlation between reduced local tumor extension and the phosphorylation of ATM, CHK2 and the presence of 53BP1, whereas no significant correlations with parameters such as survival or relapse of early-stage lung carcinomas were found.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283762.RARe2Ckgd9y1Gb2JLkvR1BUWr1Su26eVFdS2eft0ayyDo130_provenance.
NP283764.RAaQDEHssppDPZcF5rgom45tPiJ7OG2SISPM6VOrOElCA130_assertion description "[Our epidemiologic studies on invasive Group A Streptococci (GAS) infections identified specific HLA class II haplotypes/alleles conferring high-risk or protection from streptococcal toxic shock syndrome with a strong protection conferred by the DRB1*15/DQB1*06 haplotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283764.RAaQDEHssppDPZcF5rgom45tPiJ7OG2SISPM6VOrOElCA130_provenance.
NP283769.RAZJAfQXSj1eZfBIzbGp2M42BLiIYEqL8vQAig4Sst3o8130_assertion description "[Our data indicate that functional variants of MYH6 are associated with cardiac malformations in addition to ASD and provide a novel potential mechanism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283769.RAZJAfQXSj1eZfBIzbGp2M42BLiIYEqL8vQAig4Sst3o8130_provenance.
NP283770.RAcygV4BqmwxBcFVMBra0OcsvI54a7LQnQ-tBCfIB8H28130_assertion description "[This study revealed an association of CFH-rs1065489 with AU as well as uveitis recurrence frequency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283770.RAcygV4BqmwxBcFVMBra0OcsvI54a7LQnQ-tBCfIB8H28130_provenance.
NP283776.RAdfUh2xHRGuI7rqzAk9bJst7qUOc-GDaE0IQh0pIGtyM130_assertion description "[Tumour necrosis factor alpha promoter polymorphisms and etanercept therapy in juvenile idiopathic arthritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283776.RAdfUh2xHRGuI7rqzAk9bJst7qUOc-GDaE0IQh0pIGtyM130_provenance.
NP283778.RAYWf3rxdaRgQDD6K7c8tQtzReed94tSYDYMo718L3NQc130_assertion description "[Urinary trypsin inhibitor (UTI), a Kunitz-type protease inhibitor, efficiently inhibits tumor cell invasion and metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283778.RAYWf3rxdaRgQDD6K7c8tQtzReed94tSYDYMo718L3NQc130_provenance.
NP283783.RAbRQTudh-w02_BgIta3Nzqfi9D-r7fEZw5XJk6kHLX28130_assertion description "[Moreover, in situ hybridization analysis of 177 primary invasive breast carcinomas revealed overexpression of LMO4 in 56% of specimens.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283783.RAbRQTudh-w02_BgIta3Nzqfi9D-r7fEZw5XJk6kHLX28130_provenance.
NP283787.RAfcIPpxdzQNsUSjC2GvAbo1OxBdVa8IvJB1wpx2J7_0k130_assertion description "[This study examined the expression of caveolin and eNOS at the protein and mRNA levels in patients with hepatocellular carcinoma and hepatitis C-related cirrhosis, and in control noncirrhotic liver specimens obtained from patients with metastatic liver carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283787.RAfcIPpxdzQNsUSjC2GvAbo1OxBdVa8IvJB1wpx2J7_0k130_provenance.
NP283788.RAdE7mYtlRcOY68gw_DXErtC3zYgePOwgvCmmQtyFzK30130_assertion description "[However, heterozygous ATR mutations are found in human cancers with microsatellite instability, suggesting that ATR haploinsufficiency contributes to tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283788.RAdE7mYtlRcOY68gw_DXErtC3zYgePOwgvCmmQtyFzK30130_provenance.
NP283798.RAdZgb5UWryKQRb-mrMCSM6-9iNsa0ERn94cJPemT6KNY130_assertion description "[To identify dysregulated pathways in distinct phases of NOTCH1-mediated T-cell leukemogenesis, as well as small-molecule inhibitors that could synergize with or substitute for gamma-secretase inhibitors (GSIs) in T-cell acute lymphoblastic leukemia (T-ALL) therapy, we compared gene expression profiles in a Notch1-induced mouse model of T-ALL with those in human T-ALL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP283798.RAdZgb5UWryKQRb-mrMCSM6-9iNsa0ERn94cJPemT6KNY130_provenance.

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