Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence GSTM1+null+genotype+is+associated+with+benign+prostate+hyperplasia. assertion.
- assertion asSentence Examine+role+of+GSTM1+polymorphisms+in+patient+response+to+gastric+cancers+treated+with+FOLFOX+or+FOLFIRI. assertion.
- assertion asSentence GSTM1+and+GSTT1+null+genotypes+have+protective+role%28s%29+for+developing+coronary+heart+disease. assertion.
- assertion asSentence Ethnicity+affects+the+genetic+association+of+GSTM1+with+rheumatoid+arthritis+in+South+Asian+and+Caucasian+patients+living+in+East+Midlands%2FUnited+Kingdom. assertion.
- assertion asSentence GSTM1-null+individuals+demonstrated+lower+busulfan+pharmacokinetics+in+children+with+congenital+hemoglobinopathies+undergoing+hematopoietic+stem+cell+transplantation. assertion.
- assertion asSentence GSTM1+deletion+polymorphism+is+significantly+associated+with+increased+risk+of+symptomatic+benign+prostate+hyperplasia. assertion.
- assertion asSentence Genetic+polymorphisms+of+GSTM1+is+associated+with+gastric+carcinoma. assertion.
- assertion asSentence There+is+a+significant+involvement+of+the+GSTT1+and+GSTM1+polymorphisms+in+female+Pakistani+patients+having+pseudoexfoliative+glaucoma. assertion.
- assertion asSentence GSTM1+polymorphism+is+associated+with+oral+submucous+fibrosis. assertion.
- assertion asSentence No+increased+prostate+scancer+risk+for+men+carrying+any+of+the+GSTM1+or+GSTT1+genotypes. assertion.
- assertion asSentence Diminished+GSTM3+mRNA+levels+correlated+with+decreased+minichromosome+maintenance+deficient+3+%28MCM3%29+mRNA+levels+in+a+diagnostic+and+SNP-dependent+fashion+in+Alzheimer+disease. assertion.
- assertion asSentence A+T2517C+polymorphism+in+the+GSTM4+gene+is+associated+with+risk+of+developing+lung+cancer. assertion.
- assertion asSentence GSTM4+contributes+to+the+cancerous+behavior+of+Ewing%27s+sarcoma. assertion.
- assertion asSentence Reversal+of+GSTP1+CpG+island+hypermethylation+and+reactivation+of+pi-class+glutathione+S-transferase+%28GSTP1%29+expression+in+human+prostate+cancer+cells+by+treatment+with+procainamide. assertion.
- assertion asSentence Glutathione+S-transferase+P1+and+NADPH+quinone+oxidoreductase+polymorphisms+are+associated+with+aberrant+promoter+methylation+of+P16%28INK4a%29+and+O%286%29-methylguanine-DNA+methyltransferase+in+sputum. assertion.
- assertion asSentence Liver+disease+in+pediatric+patients+with+cystic+fibrosis+is+associated+with+glutathione+S-transferase+P1+polymorphism. assertion.
- assertion asSentence GSTP1+is+up-regulated+by+antiestrogens+mediated+by+estrogen+receptor+beta. assertion.
- assertion asSentence GSTP1+blocks+As%282%29O%283%29-induced+apoptosis+in+lymphoma+cells+by+decreasing+intracellular+amounts+of+H%282%29O%282%29+by+catabolism. assertion.
- assertion asSentence GSTT1%28null%29+and+GSTP1%28val%2Fval%29+polymorphisms+not+associated+with+increased+risk+of+developing+Behcet%27s+disease. assertion.
- assertion asSentence PCR+for+GSTP1+detected+prostatic+cancer+with+a+75%25+sensitivity. assertion.
- assertion asSentence Polymorphic+in+brain+cancer. assertion.
- assertion asSentence GSTP1+promotor+hypermethylation+occurs+during+carcinogenesis+and+is+considered+to+be+a+major+event+of+prostate+carcinogenesis. assertion.
- assertion asSentence Polymorphisms+within+GSTP1+do+not+play+a+major+role+in+the+development+of+bronchial+asthma+in+German+children. assertion.
- assertion asSentence Finds+no+association+of+the+GSTPI+Ilel105Val+gene+polymorphism+with+AIA+phenotype+in+the+Korean+population. assertion.
- assertion asSentence GSTT1+wildtype+and+GSTP1+GG+are+associated+with+increased+risk+of+skin+lesions. assertion.
- assertion asSentence An+animo+acid+substituition+is+a+risk+factor+for+breast+cancer. assertion.
- assertion asSentence GSTP1+genotype+coding+for+an+enzyme+with+high+conjugation+capacity+significantly+increases+the+risk+of+developing+asbestosis. assertion.
- assertion asSentence GSTP1+prevented+LPS-induced+TNF-alpha%2C+IL-1beta%2C+MCP-1+and+NO+production. assertion.
- assertion asSentence Somatic+promoter+hypermethylation+and+impaired+ERK+signaling+are+associated+with+decreased+GSTP1+expression+and+CDDP+sensitivity+in+gastric+cancer+cell+lines. assertion.
- assertion asSentence Reduced+expression+of+glutathione-s-transferase+pi+in+patients+with+esophageal+squamous+cell+carcinoma. assertion.
- assertion asSentence Lower+frequency+of+the+single+nucleotide+polymorphisms+in+GSTP1+is+associated+with+hypertension%2C+thrombophilia+and+oxidative+stress+in+mexican+populations. assertion.
- assertion asSentence Urinary+1-hydroxypyrene+concentrations+can+be+modified+by+GSTM1%2C+GSTT1+and+GSTP1+gene+polymorphisms. assertion.
- assertion asSentence GSTP1+promoter+methylation+is+associated+with+prostate+cancer. assertion.
- assertion asSentence Glutathione+S-transferase+P1+polymorphisms+are+associated+with+time+to+tumor+progression+in+small+cell+lung+cancer. assertion.
- assertion asSentence Association+between+genetic+polymorphisms+of+the+GSTP1+gene+and+bone+mineral+density+variation+and+biochemical+bone+remodeling+markers+in+pre-+and+post-menopausal+women. assertion.
- assertion asSentence GSTP1+down-regulation+is+involved+in+human+bronchial+epithelial+carcinogenesis. assertion.
- assertion asSentence The+carcinogenic+effects+of+DCM+in+humans+are+caused+by+the+interaction+with+DNA+of+a+glutathione+%28GSH%29+conjugate+that+is+produced+by+the+class+theta+glutathione+S-transferase+T1-1+%28GST+T1-1%29. assertion.
- assertion asSentence Polymorphism+is+not+associated+with+laryngeal+cancer+risk+in+Caucasians. assertion.
- assertion asSentence Genetic+polymorphisms+of+GSTT1+found+in+head+and+neck+squamous+cell+carcinoma. assertion.
- assertion asSentence GSTT1+deletion+increrases+the+risk+for+MALT+lymphoma+in+a+chinese+population. assertion.
- assertion asSentence Polymorphic+in+brain+cancer. assertion.
- assertion asSentence The+GSTT1+null+genotype%2C+particularly+if+it+is+associated+with+the+GSTM1+null+genotype%2C+greatly+increases+the+risk+for+colorectal+and+gastric+cancers. assertion.
- assertion asSentence Null+genotypes+of+GSTT1+is+associated+with+inflammatory+bowel+diseases. assertion.
- assertion asSentence Functional+GSTT-1+phenotypes+do+not+correlate+with+susceptibility+to+or+severity+of+acute+pancreatitis+in+a+patient+population+from+Pittsburgh%2C+Pa.%2C+USA. assertion.
- assertion asSentence Genetic+polymorphisms+of+metabolic+enzymes+CYP1A1%2C+CYP2D6%2C+GSTM1+and+GSTT1+and+leukemia+susceptibility. assertion.
- assertion asSentence Diabetics+with+null+GSTT1+genotypes+are+substantially+at+higher+risk+for+developing+complications. assertion.
- assertion asSentence GST+and+mEPHX+variants+share+a+positive+association+with+viral-related+hepatocellular+carcinoma+risk+in+Indian+population. assertion.
- assertion asSentence Coronary+heart+disease+patients+have+an+increased+incidence+of+both+GSTM+and+GSTT+null+polymorphisms. assertion.
- assertion asSentence There+are+no+relationship+between+GSTT1+and+GSTM1+gene+deletions+and+hepatic+damage+caused+by+HBV. assertion.
- assertion asSentence Single-nucleotide+polymorphic+variants+of+GSTT1+differ+in+stability+and+functional+properties. assertion.
- assertion asSentence Genetic+peculiarities+particularly+xenobiotic+detoxification+enzymes+CYP1A1%2C+CYP2E1%2C+EPHX1+and+GSTM1%2C+GSTT1+play+important+role+in+pulmonary+diseases+development. assertion.
- assertion asSentence Genetic+polymorphism+of+glutathione+S+transferases+T1+is+associated+with+hepatocellular+carcinoma. assertion.
- assertion asSentence Genetic+polymorphisms+of+GSTT1+is+not+associated+with+gastric+carcinoma. assertion.
- assertion asSentence The+GSTT1+polymorphism+influences+the+outcome+of+Brazilian+patients+with+Hodgkin+lymphoma. assertion.
- assertion asSentence There+is+a+significant+involvement+of+the+GSTT1+and+GSTM1+polymorphisms+in+female+Pakistani+patients+having+pseudoexfoliative+glaucoma. assertion.
- assertion asSentence GSTT1+deletion+polymorphism+is+associated+with+oral+cancer+progression. assertion.
- assertion asSentence Copy+number+variations+of+GSTT1+is+not+associated+with+colorectal+cancer+risk+or+for+an+effective+modification+of+cigarette+smoking+and+menopausal+hormone+therapy. assertion.
- assertion asSentence Deletion+polymorphism+of+GSTT1+glutathione+transferase+gene+is+recommended+as+a+marker+for+predictive+diagnostics+of+development+and+progress+of+chronic+obstructive+pulmonary+disease. assertion.
- assertion asSentence MSH6%2FMUTYH+heterozygote+mutation+carriers+display+a+predominant+HNPCC+molecular+tumour+phenotype%2C+with+microsatellite+instability+and+underrepresentation+of+G%3ET+transversions. assertion.
- assertion asSentence Tumours+with+loss+of+MSH6+expression+are+MSI-H+when+screened+with+a+pentaplex+of+five+mononucleotide+repeats. assertion.
- assertion asSentence Collapse+of+the+transcription+bubble+defines+the+RNA+polymerase+II+promoter+clearance+transition. assertion.
- assertion asSentence The+specific+binding+of+the+C-terminal+acidic+domain+%28AC-D%29+of+the+human+TFIIEalpha+subunit+to+the+pleckstrin+homology+domain+%28PH-D%29+of+the+human+TFIIH+p62+subunit+is+demonstrated. assertion.
- assertion asSentence alpha1-Helix+of+RAP74+is+important+for+supporting+NTP-driven+translocation+by+RNAP+II. assertion.
- assertion asSentence p62+subunit+of+TFIIH+interacts+with+TRbeta+in+a+ligand-dependent+manner. assertion.
- assertion asSentence The+pleckstrin+homology+domain+from+the+62+kDa+subunit+Tfb1+%28residues+1-108%29+of+TFIIH+is+sufficient+for+binding+to+the+activation+domain+of+herpes+simplex+virus+protein+VP16. assertion.
- assertion asSentence The+CO+binding+affinity+of+soluble+guanylate+cyclase+alpha+2+subunit+is+threefold+greater+than+that+of+human+soluble+guanylate+cyclase+alpha+1+subunit. assertion.
- assertion asSentence ABH+blood+group+antigens+in+N-glycan+of+human+glycophorin+A. assertion.
- assertion asSentence The+S-s-U%2Bvar+phenotype+arises+from+changes+in+or+around+GYPB+exon+5. assertion.
- assertion asSentence The+N-terminal+GzmA+cleavage+fragment+of+PARP-1+acts+as+a+PARP-1+dominant+negative%2C+binding+to+DNA+and+blocking+DNA+repair. assertion.
- assertion asSentence Patients+with+chronic+immune+thrombocytopenia+have+elevated+serum+granzyme+A+levels. assertion.
- assertion asSentence TNFalpha-+and+FasL-stimulated+acute+myeloid+leukemia+cell+lytic+induction+is+regulated+by+a+signalling+pathway+involving+sequentially%2C+radical+oxygen+species+generation%2C+Trx+oxidation%2C+ASK1+activation%2C+p38MAPK+stimulation+and+GrB+induction. assertion.
- assertion asSentence Granzyme+B+is+expressed+and+released+by+human+mast+cells+upon+physiologic+stimulation. assertion.
- assertion asSentence Accessible+chromatin-associated+%28histone+3+lysine+9%29+acetylation+state+serves+as+a+cornerstone+for+differentially+high+expression+of+effector+gene+eomesodermin+and+its+targets+perforin+1+and+granzyme+B+in+memory+CD8+T+cells. assertion.
- assertion asSentence The+production+of+GzmB+by+strongly+activated+CD4+T+cells+represents+a+mechanism+by+which+CD4+T+cells+resist+Treg+suppression. assertion.
- assertion asSentence Upregulation+of+granzyme+B+is+associated+with+acute+pancreas+allograft+rejection. assertion.
- assertion asSentence A+critical+and+previously+unsuspected+role+is+revealed+for+granzymes+A+and+B+in+dictating+immunogenicity+by+influencing+the+mode+of+tumor+cell+death. assertion.
- assertion asSentence Following+GzmB+uptake%2C+Plasmodium+falciparum-infected+erythrocytes+undergo+eryptosis+via+a+perforin-independent%2C+GzmB-mediated+mechanism. assertion.
- assertion asSentence Structure-based+mutagenesis+reveals+that+the+amino-terminus+and+catalytic+triad+of+GzmM+are+most+essential+for+proteolytic+function. assertion.
- assertion asSentence FoxP3+interacts+with+H1.5+to+alter+its+binding+to+target+genes+to+modulate+their+expression+and+to+program+Treg+function. assertion.
- assertion asSentence Histone+gamma-H2AX+promotes+binding+of+nuclear+DNA+helicase+II+to+transcriptionally+stalled+sites+on+chromosomal+DNA. assertion.
- assertion asSentence Copy+number+alterations+of+the+H2AFX+gene+in+sporadic+breast+cancer+patients. assertion.
- assertion asSentence Changes+in+chromatin+structure+are+sufficient+to+elicit+extensive+gamma-H2AX+formation+in+the+relative+absence+of+DNA+strand+breaks. assertion.
- assertion asSentence Gamma-H2AX+has+important+role+for+effective+DNA+double-strand+breaks+dependent+activation+of+ATM-related+damage+responses+via+NBS1. assertion.
- assertion asSentence miR-24+upregulation+in+postreplicative+cells+reduces+H2AX+and+makes+them+vulnerable+to+DNA+damage. assertion.
- assertion asSentence The+gammaH2AX+foci+change+composition+during+the+cell+cycle%2C+with+proteins+53BP1%2C+NBS1+and+MRE11+dissociating+from+foci+in+G%282%29+and+mitosis+to+return+at+the+beginning+of+the+following+G%281%29. assertion.
- assertion asSentence Histone+deacetylase+inhibitors+valproic+acid+and+depsipeptide+sensitize+retinoblastoma+cells+to+radiotherapy+by+increasing+H2AX+phosphorylation+and+p53+acetylation-phosphorylation. assertion.
- assertion asSentence A+distinct+monoubiquitination-dependent+mechanism+that+is+required+for+H2AX+phosphorylation+and+the+initiation+of+DDR. assertion.
- assertion asSentence Upon+DNA+damage%2C+histone+H2A.Z+is+first+evicted+from+the+p21+promoter%2C+followed+by+the+recruitment+of+the+Tip60+histone+acetyltransferase+to+activate+p21+transcription. assertion.
- assertion asSentence Acetylation+of+H2A.Z+is+a+key+modification+associated+with+gene+activity+in+normal+cells+and+epigenetic+gene+deregulation+in+tumorigenesis. assertion.
- assertion asSentence Failed+to+validate+association+of+FSAP+gene+polymorphisms+with+venous+thromboembolism+amoung+Californians+of+European+ancestry. assertion.
- assertion asSentence Neither+maternal+nor+fetal+heterozygosity+for+the+E474Q+mutation+is+a+relevant+factor+of+HELLP+syndrome. assertion.
- assertion asSentence A+proteolytically+sensitive+conformation+of+HisRS+exists+in+the+lung%2C+the+target+tissue+associated+with+this+autoantibody+response. assertion.
- assertion asSentence Antisense+inhibition+of+HAS2+in+osteosarcoma+cells+inhibits+hyaluronan+retention+and+tumorigenicity. assertion.
- assertion asSentence Quaternary+structure+of+hemoglobin+in+solution. assertion.
- assertion asSentence Aasociated+with+cardiovascular+disease+and+coronary+diseasse+risk+in+Asian-Indian+subjects+with+normal+glucose+tolerance. assertion.
- assertion asSentence Red+cell+life+span+heterogeneity+in+hematologically+normal+people+is+sufficient+to+alter+HbA1c. assertion.
- assertion asSentence The+polyethylene+glycol+chains+conjugated+at+Val-1%28alpha%29+decrease+the+Hill+coefficient%2C+the+Bohr+effect+of+Hb+and+the+sensitization+to+the+presence+of+the+allosteric+effectors. assertion.
- assertion asSentence Chain-selective+substitution+of+mesoheme+into+Hb+coupled+with+time-resolved+resonance+Raman+spectroscopy+has+revealed+identical+geminate+CO+recombination+yields+for+alpha+and+beta+chains. assertion.
- assertion asSentence HbA1c+is+associated+with+severity+of+obstructive+sleep+apnea+hypopnea+syndrome+in+nondiabetic+men. assertion.
- assertion asSentence Dried+blood+can+be+used+for+measurement+of+glycaated+hemoglobin+A1C+by+an+immunoturbidimetric+method. assertion.