Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP288337.RAUxbb-EQGHulH6bI6q3cMnHGt010Msz3dSnCoa3KbyAc130_assertion description "[Immunohistochemical analysis of expression of a 65 kDa oncofetal protein (p65), epidermal growth factor receptor (EGFR), oncogene c-erb B2 and tumor suppressor gene p53 protein products in breast cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288337.RAUxbb-EQGHulH6bI6q3cMnHGt010Msz3dSnCoa3KbyAc130_provenance.
- NP288339.RAe3pq9LFlhWmD-Cu-cR7-MH4px0pf5mX_8B708aRDG-E130_assertion description "[NRAMP1/SLC11A1 gene polymorphisms and host susceptibility to Mycobacterium tuberculosis and M. leprae in South Sulawesi, Indonesia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288339.RAe3pq9LFlhWmD-Cu-cR7-MH4px0pf5mX_8B708aRDG-E130_provenance.
- NP288340.RAZwHdGnGLIuNfnWVTA0pVRN5c_ulPPoYbeRRjDDoDBYM130_assertion description "[Our findings are consistent with the theory of reduced dopamine D(2) receptor (D2R) availability in dystonia, although the possibility of increased endogenous dopamine, and consequently, competitive D2R occupancy cannot be ruled out.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288340.RAZwHdGnGLIuNfnWVTA0pVRN5c_ulPPoYbeRRjDDoDBYM130_provenance.
- NP288341.RAeSwVwp3PoRrgqHQ60Z-MldJKCcJSbnWnp9kBSzYEJ8w130_assertion description "[In addition, we found increased expression of Sqstm1 transcripts during CSF3-induced neutrophil differentiation of 32D-CSF3R cells and an inverse correlation of SQSTM1 protein levels and miR-106 expression in AML samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288341.RAeSwVwp3PoRrgqHQ60Z-MldJKCcJSbnWnp9kBSzYEJ8w130_provenance.
- NP288343.RAdI3oENbLlt8DrJICuZBcTN2swD_l9a2sKbnxZH1ScmA130_assertion description "[A human clusterin ASO targeting the translation initiation site and incorporating MOE-gapmer backbone (OGX-011) synergistically enhanced the cytotoxic effects of paclitaxel in human xenografts of prostate, renal cell, bladder, and lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288343.RAdI3oENbLlt8DrJICuZBcTN2swD_l9a2sKbnxZH1ScmA130_provenance.
- NP288345.RAR44qm2aaSP0cz7g-eW_H_eutEHhtYckSV-F9xN-V4M4130_assertion description "[The steroid coactivator AIB1 (Ampified In Breast cancer 1) is a member of the SRC-1 family of transactivation coactivators that is amplified in about 7% of breast tumor samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288345.RAR44qm2aaSP0cz7g-eW_H_eutEHhtYckSV-F9xN-V4M4130_provenance.
- NP288346.RAaz1lMDuzWazDU-LLNZ_lYU4my5MlWZ-A4XEPamd4aTg130_assertion description "[However, most recent published data on deep brain stimulation (DBS) for dystonia, applied to different targets and patients, are still mainly from uncontrolled case reports (especially for secondary dystonia).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288346.RAaz1lMDuzWazDU-LLNZ_lYU4my5MlWZ-A4XEPamd4aTg130_provenance.
- NP288351.RASxXioTirQxo5R0jo9ESNeth-_bBi6iqI9iD0fx0BCi0130_assertion description "[To investigate the effect of HTLV-1 infection on CD4+ T-cell subsets, we used flow cytometry to analyze the T-cell phenotype and HTLV-1 infection in peripheral mononuclear cells (PBMCs) of four groups of subjects, including 23 HTLV-1-infected asymptomatic carriers (AC), 10 patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), 10 patients with adult T-cell leukemia (ATL), and 10 healthy donors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288351.RASxXioTirQxo5R0jo9ESNeth-_bBi6iqI9iD0fx0BCi0130_provenance.
- NP288352.RARmCStJC3nDrHvMmupGSQqd8cFbjoISg_aLUyhXvohh8130_assertion description "[Here we challenge this view with evidence that genetic ablation of IL-10 in the mouse significantly heightens sensitivity to chemical carcinogenesis, growth of transplanted tumors, and formation of metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288352.RARmCStJC3nDrHvMmupGSQqd8cFbjoISg_aLUyhXvohh8130_provenance.
- NP288361.RAVwYmtL-yuMGchyRO3K0Pv8IxeTp3mBVJmdkqhpYBcu8130_assertion description "[Thus, we identified a novel mechanism that governs B7-H6 expression in tumor cells that has implications for potential cancer treatments combining immunotherapy with HDACi.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288361.RAVwYmtL-yuMGchyRO3K0Pv8IxeTp3mBVJmdkqhpYBcu8130_provenance.
- NP288367.RAfg4V_m8UyBKrb7WeNmd1vm-uvWuqMraGR6tXPn0k7oU130_assertion description "[Mutations in the spastin (SPG4) gene are responsible for approximately 40% of autosomal dominant HSP (AD-HSP) and 6.5-18% of sporadic cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288367.RAfg4V_m8UyBKrb7WeNmd1vm-uvWuqMraGR6tXPn0k7oU130_provenance.
- NP288372.RAamjMJHQg2pzk_Kq_TIgDKrkdBFVaG50ZDnQoR4R-SWI130_assertion description "[In particular, genetic polymorphisms for NQO1, CYP2E1, and ALDH2 synergistically with cumulative smoking amounts and alcohol drinking levels interact in the carcinogenesis of lung cancer in Koreans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288372.RAamjMJHQg2pzk_Kq_TIgDKrkdBFVaG50ZDnQoR4R-SWI130_provenance.
- NP288374.RARJEMLKxlIvmgA_gcdCHhXRnXkklGYoHJRvvQcvgXK1Q130_assertion description "[To characterize genetic contributions toward aberrant splicing of the hyaluronan synthase 1 (HAS1) gene in multiple myeloma (MM) and Waldenstrom macroglobulinemia (WM), we sequenced 3616 bp in HAS1 exons and introns involved in aberrant splicing, from 17 patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288374.RARJEMLKxlIvmgA_gcdCHhXRnXkklGYoHJRvvQcvgXK1Q130_provenance.
- NP288380.RAVQq-HtSebjJsFcMlWU-AfctH69eZcWGeRFwnUE8_A8c130_assertion description "[Genetic analysis demonstrated the absence of an usual FMTC mutation and the presence of a germline 9-bp duplication in RET exon 8 in the heterozygous state in all patients with MTC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288380.RAVQq-HtSebjJsFcMlWU-AfctH69eZcWGeRFwnUE8_A8c130_provenance.
- NP288397.RAYXl__ImBxNHqcDf5ZGlFA3GNbb5eQOwI0idhBOLjXQQ130_assertion description "[Our results identify TCF3 as a central regulator of tumor growth and initiation, and a novel link between stem cells and cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288397.RAYXl__ImBxNHqcDf5ZGlFA3GNbb5eQOwI0idhBOLjXQQ130_provenance.
- NP288401.RAQaTiXXz_FwwGbSiltXv_kDjvkPb8hBQo4Z2i_cgReIA130_assertion description "[This assumption was initially confirmed by functional analyses showing that both IL-9 and Th2 cells play an important role in the pathogenesis of asthma, IgE class switch recombination, and resolution of parasitic infections.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288401.RAQaTiXXz_FwwGbSiltXv_kDjvkPb8hBQo4Z2i_cgReIA130_provenance.
- NP288402.RAT66VjeLygGXQ30Q-c-0VdQtoRIboo5MO8XSRW4KXeJ0130_assertion description "[It is well-known that male breast cancer (MBC) susceptibility is mainly due to high-penetrance BRCA1/2 mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288402.RAT66VjeLygGXQ30Q-c-0VdQtoRIboo5MO8XSRW4KXeJ0130_provenance.
- NP288405.RAVviUbE8btLEzeab8UbYDcJewEouu5SCvkeZO0fy4Amc130_assertion description "[Autosomal recessive mental retardation, deafness, ankylosis, and mild hypophosphatemia associated with a novel ANKH mutation in a consanguineous family.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288405.RAVviUbE8btLEzeab8UbYDcJewEouu5SCvkeZO0fy4Amc130_provenance.
- NP288409.RAXxkkJMfWyiXVUTlAqyHRcHy-hTJa2VB3xBv1VT6nCmo130_assertion description "[The purpose of this longitudinal study was to examine the changes in the p53 gene in progressive, sequential epithelial dysplasias and carcinomas from the oral cavity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288409.RAXxkkJMfWyiXVUTlAqyHRcHy-hTJa2VB3xBv1VT6nCmo130_provenance.
- NP288417.RAQCIdY4F0rIhqqPMMFgELpC6CqR2JCbT0nTg69K9bQgk130_assertion description "[Generalized alterations in beta-adrenergic signalling, including betaARK1, could be a major contributory factor in the development of LVH in hypertension, and the concentration of betaARK1 in lymphocytes can reflect the development of LVH in a patient with hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288417.RAQCIdY4F0rIhqqPMMFgELpC6CqR2JCbT0nTg69K9bQgk130_provenance.
- NP288418.RAfnQ2whAchMhoau-smHEM-zGNLBVNXkdUqd_d3uv2reg130_assertion description "[In a study of 1,604 incident colon cancer cases and 1,969 matched population-based controls genotyped for BER variants OGG1 (S326C) and XRCC1 (R194W, R280H, and R399Q), we found no associations with colon cancer overall.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288418.RAfnQ2whAchMhoau-smHEM-zGNLBVNXkdUqd_d3uv2reg130_provenance.
- NP288431.RAa35DB3v5bDEKgL2UDbgWIw1upizYo0pR4EuxCk4j68s130_assertion description "[Here, we demonstrate that adenovirus-mediated overexpression of SIRT1 in the liver of diet-induced insulin-resistant low-density lipoprotein receptor-deficient mice and of genetically obese ob/ob mice attenuates hepatic steatosis and ameliorates systemic insulin resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288431.RAa35DB3v5bDEKgL2UDbgWIw1upizYo0pR4EuxCk4j68s130_provenance.
- NP288432.RAY4vEGy1LFRvtaaoI4z7XtCqHaCgWQStwxCX9nj5xx2M130_assertion description "[Pretreatment with a monoclonal antibody/interleukin-2 fusion protein directed against DNA enhances the delivery of therapeutic molecules to solid tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288432.RAY4vEGy1LFRvtaaoI4z7XtCqHaCgWQStwxCX9nj5xx2M130_provenance.
- NP288434.RAXrVGcOuLHb2YGCKKQdofNmVpAHDSCATWGupsejICYtA130_assertion description "[Expression of the c-myc proto-oncogene in multiple myeloma and chronic lymphocytic leukemia: an in situ analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288434.RAXrVGcOuLHb2YGCKKQdofNmVpAHDSCATWGupsejICYtA130_provenance.
- NP288436.RAX38Tv04kIZkLsEvve428Y6DA2LKVBpRvt2lMTiQKWmI130_assertion description "[Recently, it has been shown that mutations in the HRPT2 gene (encoding parafibromin) are associated with the development of parathyroid carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288436.RAX38Tv04kIZkLsEvve428Y6DA2LKVBpRvt2lMTiQKWmI130_provenance.
- NP288438.RAaNQ7NtvVp0cTv6PVYfQMXwPNxiTF-OYjID9rH_1vs60130_assertion description "[The origin and function of soluble CD14 in experimental bacterial meningitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288438.RAaNQ7NtvVp0cTv6PVYfQMXwPNxiTF-OYjID9rH_1vs60130_provenance.
- NP288440.RARkKiFjBTWpjDLn6xyihe6SVBVvXIiToAwtfFWyKcSfw130_assertion description "[The significance of fibroblast growth factor receptor 2 expression in differentiation of hepatocellular carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288440.RARkKiFjBTWpjDLn6xyihe6SVBVvXIiToAwtfFWyKcSfw130_provenance.
- NP288443.RASVkLy-MxtBGfDk8GSW42DrmlnU8MTsz4OexfFq4Ew5c130_assertion description "[Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288443.RASVkLy-MxtBGfDk8GSW42DrmlnU8MTsz4OexfFq4Ew5c130_provenance.
- NP288444.RAe_t3ffLZKPh-Q4vYpO8s-FdUyr-KVWIYU0bLb54SYZQ130_assertion description "[Reduction in expression levels of glutathione S-transferase (GST) mu type 1 (GSTM1) in stroke-prone spontaneously hypertensive rats has recently been reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288444.RAe_t3ffLZKPh-Q4vYpO8s-FdUyr-KVWIYU0bLb54SYZQ130_provenance.
- NP288447.RAeSbWBkbJCIIb_RIUQMpO_1TPWwAm2nEJu_nVcysHYSQ130_assertion description "[Using genome-wide single-nucleotide polymorphism array to evaluate for regions of recurrent copy variation, we identified deletions at known DBA-related ribosomal protein gene loci in 17% (9 of 51) of patients without an identifiable mutation, including RPS19, RPS17, RPS26, and RPL35A.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288447.RAeSbWBkbJCIIb_RIUQMpO_1TPWwAm2nEJu_nVcysHYSQ130_provenance.
- NP288449.RAdnfvsm4sZwew9t72x6TP9SehGQdWy_WgRO7pueMlriU130_assertion description "[Recently, analysis of the TATA box-binding protein (TBP) gene, one of the transcription factors known to contain a CAG/CAA repeat, in patients with progressive cerebellar ataxia revealed one sporadic case with 63 repeats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288449.RAdnfvsm4sZwew9t72x6TP9SehGQdWy_WgRO7pueMlriU130_provenance.
- NP288452.RAeFbxUttbkjKgWivHSnheEbQGT8uDybhFRwmw1-79gN4130_assertion description "[Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288452.RAeFbxUttbkjKgWivHSnheEbQGT8uDybhFRwmw1-79gN4130_provenance.
- NP288455.RAfIDmO0w1U2dCNpDAVTZNZrDGEfGajtggqc4r4ZZFJ04130_assertion description "[Specifically, we aimed to optimize the therapeutic efficacy of Flt3L/TK treatment in the RG2 model by overexpressing the following genes within the brain tumor microenvironment: 1) a TK mutant with enhanced cytotoxicity (SR39 mutant TK), 2) Flt3L-IgG fusion protein that has a longer half-life, 3) CD40L to stimulate DC maturation, 4) T helper cell type 1 polarizing dendritic cell cytokines interleukin-12 or C-X-C motif ligand 10 chemokine (CXCL)-10, 5) C-C motif ligand 2 chemokine (CCL2) or C-C motif ligand 3 chemokine (CCL3) to enhance dendritic cell recruitment into the tumor microenvironment, 6) T helper cell type 1 cytokines interferon-γ or interleukin-2 to enhance effector T-cell functions, and 7) IκBα or p65RHD (nuclear factor kappa-B [NF-κB] inhibitors) to suppress the function of Foxp3+ Tregs and enhanced effector T-cell functions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288455.RAfIDmO0w1U2dCNpDAVTZNZrDGEfGajtggqc4r4ZZFJ04130_provenance.
- NP288459.RATW_TxYmPVZm6kd0I2Qy1stT0UHTkeS_KVW06kXAB9BI130_assertion description "[There is a considerable amount of evidence supporting a role for the 5-HT(7) receptor in depression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288459.RATW_TxYmPVZm6kd0I2Qy1stT0UHTkeS_KVW06kXAB9BI130_provenance.
- NP288466.RARIo6wtICHbH6DvAs-VIu4I92_abABrOUrfnhFFMI2Tw130_assertion description "[Mice fed the 45% fat diet had more moderate obesity, less glucose intolerance, and lower WAT macrophage/inflammatory marker mRNA abundances compared with 60% fat-fed mice; TNFα and CD68 mRNA levels were ~2- and ~5-fold of control levels (P < 0.01).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288466.RARIo6wtICHbH6DvAs-VIu4I92_abABrOUrfnhFFMI2Tw130_provenance.
- NP288474.RAXEZbAEY7nFmLKTonvSyoZmUV9SKACX23lR3ebsz8Y7c130_assertion description "[rs4925648 and rs10925019 were the most strongly associated with CD susceptibility (P = 0.001, odds ratio (OR) 1.62, 95% CI 1.2-2.18; and P = 6.5 x 10(-4), OR 1.65, 95% CI 1.23-2.19, respectively).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288474.RAXEZbAEY7nFmLKTonvSyoZmUV9SKACX23lR3ebsz8Y7c130_provenance.
- NP288476.RAbWwSZtiHHVQsCwHWbosbC4Akbu2p4XiFqJQjaDnSALY130_assertion description "[High 4-HNE expression correlated with high DAS28-CRP (P = 0.02; r = 0.53), tender joint count for 28 joints (TJC-28) (P = 0.03; r = 0.49), swollen joint count for 28 joints (SJC-28) (P = 0.03; r = 0.50) and visual analogue scale (VAS) (P = 0.04; r = 0.48).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288476.RAbWwSZtiHHVQsCwHWbosbC4Akbu2p4XiFqJQjaDnSALY130_provenance.
- NP288478.RAUV9iJKdadOzxpMT1_2n8g9fQ5kAFKImkdlpMaTuhmqM130_assertion description "[Analysis of the phenotypic features of OTX2-positive A/M patients in this study and those previously reported suggests the presence of pituitary anomalies and lack of genitourinary and gastrointestinal manifestations as potential distinguishing characteristics from SOX2 anophthalmia syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288478.RAUV9iJKdadOzxpMT1_2n8g9fQ5kAFKImkdlpMaTuhmqM130_provenance.
- NP288502.RAQvabNIv1oMgG06VFZAodzZSx5Y87x8QXjrV7lAC4_yM130_assertion description "[Fatty acid synthase (FAS) and SREBP-1c expression were not significantly induced in NAFLD, while ATP-binding cassette sub-family G member 1 (ABCG1), a transporter involved in cholesterol egress, and acyl-CoA-cholesterol acyltransferase mRNA levels were modestly increased (1.5- to 2.5-fold, p<0.05), regardless of fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288502.RAQvabNIv1oMgG06VFZAodzZSx5Y87x8QXjrV7lAC4_yM130_provenance.
- NP288505.RATUPWqgbeBoai3iDwVSp85PZFvRUooYL7Or6keayiaKY130_assertion description "[Genotyping for CTLA4 (49 A/G, -318 C/T, and CT60 A/G), CD28 (IVS3+ 17T/C), and ICOS (c.602 A/C and c.1624C/T) was performed for 62 patients with gastric MALT lymphoma and compared with 250 unrelated healthy controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288505.RATUPWqgbeBoai3iDwVSp85PZFvRUooYL7Or6keayiaKY130_provenance.
- NP288512.RAcV4dY-gBujHW6e2Kn1vjDk6J2kWkPY-KZmyRiy51OZQ130_assertion description "[Although DPw1 was represented on extended haplotypes with greater frequency than on 113 non-A1,-B8,-SCO1,-DR3 haplotypes (0.26 vs. 0.03; P < 0.001), there were no significant differences between healthy individuals with this haplotype and those with autoimmune disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288512.RAcV4dY-gBujHW6e2Kn1vjDk6J2kWkPY-KZmyRiy51OZQ130_provenance.
- NP288515.RAYCv0wTmqRyIH4B5s-oNX0ek0CAvKzJiHZSDFHpk8Bf4130_assertion description "[We further demonstrated highly frequent expression of CCR4 in fresh ATL cells by (1) reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of CCR4 expression in peripheral blood mononuclear cells (PBMCs) from patients with ATL and healthy controls; (2) flow cytometric analysis of CCR4-expressing cells in PBMCs from patients with ATL and healthy controls; (3) CCR4 staining of routine blood smears from patients with ATL; and (4) an efficient migration of fresh ATL cells to the CCR4 ligands, TARC/CCL17 and MDC/CCL22, in chemotaxis assays.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288515.RAYCv0wTmqRyIH4B5s-oNX0ek0CAvKzJiHZSDFHpk8Bf4130_provenance.
- NP288521.RATkeD355mG8RHXv0BbL6dE-YdhW99CMzHmLRvhRGfb9U130_assertion description "[These results suggest that increased DNA methylation is another mechanism of silencing of the p27 gene in some pituitary tumors and possibly in other types of neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288521.RATkeD355mG8RHXv0BbL6dE-YdhW99CMzHmLRvhRGfb9U130_provenance.
- NP288529.RAWRd27wMWKs18Artbm8zk1KRwpa-nX59gFZhTMZlxXlk130_assertion description "[We demonstrate that unique or clonotypic MLL-AF4 genomic fusion sequences are present and detectable in neonatal blood spots from individuals who were diagnosed with acute lymphoblastic leukemia at ages 5 months to 2 years and, therefore, have arisen during fetal hematopoiesis in utero.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288529.RAWRd27wMWKs18Artbm8zk1KRwpa-nX59gFZhTMZlxXlk130_provenance.
- NP288534.RAaZKzLAAneXPjyyEMtjb5vYj7n3hS5Jj4bAyDzPUNy8k130_assertion description "[Mutations in the gene encoding the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) chloride channel give rise to the most common lethal genetic disease of Caucasian populations, CF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288534.RAaZKzLAAneXPjyyEMtjb5vYj7n3hS5Jj4bAyDzPUNy8k130_provenance.
- NP288536.RAV2B5juwj2hjghJl5oaFrn7ljfkHTeEMehdBJ5PHTKXs130_assertion description "[ACAT catalyzes the formation of cholesteryl esters (CE) in monocytes/macrophages, and it promotes the foam cell formation at the early stage of atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288536.RAV2B5juwj2hjghJl5oaFrn7ljfkHTeEMehdBJ5PHTKXs130_provenance.
- NP288540.RAbjLxiQUOn7o3GZmuk-5kY3fCoj5J1voRLbLx6mrdNyM130_assertion description "[Whereas Wilms' tumor was the most frequent tumor seen in BWS cases with UPD for 11p15 or H19 hypermethylation, none of the embryonal tumors with imprinting defects at KCNQ1OT1 was a Wilms' tumor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288540.RAbjLxiQUOn7o3GZmuk-5kY3fCoj5J1voRLbLx6mrdNyM130_provenance.
- NP288541.RAU7L-MMYlidn9eGXunq-nI75xXa_ud1hIG6SZ67S1HaA130_assertion description "[These clinical and molecular findings suggest that (1) a broader range of conductive hearing-loss phenotypes are associated with NOG mutations than had previously been recognized, (2) patients with sporadic or familial nonsyndromic otosclerosis should be evaluated for mild features of this syndrome, and (3) NOG alterations should be considered in conductive hearing loss with subtle clinical and skeletal features, even in the absence of symphalangism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288541.RAU7L-MMYlidn9eGXunq-nI75xXa_ud1hIG6SZ67S1HaA130_provenance.
- NP288544.RAYattBUKY8_CwJxDDz3jS6uOb86otjoxk2qnli68XRAE130_assertion description "[No associations with lung cancer risk were found for the XRCC1 -77 T/C, the XPA -4 G/A and the XPC PAT polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288544.RAYattBUKY8_CwJxDDz3jS6uOb86otjoxk2qnli68XRAE130_provenance.
- NP288546.RAQj2yc9n6DhVQOtYP6ZTKpY1hxG_X1cNetixTViTSiyM130_assertion description "[Statistical analysis revealed a positive correlation between granzyme A (P < .001) and granzyme B (P = .006) expression levels and the number of pack-years in smoking patients with asthma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288546.RAQj2yc9n6DhVQOtYP6ZTKpY1hxG_X1cNetixTViTSiyM130_provenance.
- NP288548.RAa4O97o5Id61V9Yr9brzcTx4pqYJB0LwPBqXwFfXe8hg130_assertion description "[The ligands of this receptor, epidermal growth factor and transforming growth factor alpha, lacked quantitative changes at their loci in gliomas and meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288548.RAa4O97o5Id61V9Yr9brzcTx4pqYJB0LwPBqXwFfXe8hg130_provenance.
- NP288550.RAew5K-vbWE2Mb_zkufE39i8VgurkDLQmXNgxuZ1qmflI130_assertion description "[Furthermore, monoclonal antibodies such as 5C9 may well provide the basis of new drugs to control TSHR activity including applications in thyroid cancer and Graves' ophthalmopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288550.RAew5K-vbWE2Mb_zkufE39i8VgurkDLQmXNgxuZ1qmflI130_provenance.
- NP288560.RAXxEhmXtl1sJhvyuxPExoVJ2Hc3DWsbSgqWBMMSC0bNw130_assertion description "[Perforation injury to the eye can protect against retinal degeneration and pigment epithelial derived factor (PEDF) may play a role in this neuro-protective effect.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288560.RAXxEhmXtl1sJhvyuxPExoVJ2Hc3DWsbSgqWBMMSC0bNw130_provenance.
- NP288582.RAbDqDsX_kQpqLJzd_lw3peYrjUWkPNypDv1GUwtp3Fi8130_assertion description "[In this review, we highlight recent advances in studies of the oncogenic role of Jab1/CSN5 in NPC and its potential as a therapeutic target for this cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288582.RAbDqDsX_kQpqLJzd_lw3peYrjUWkPNypDv1GUwtp3Fi8130_provenance.
- NP288583.RAcZNGtW-4rCDRRs0JkTSwoQb8Kjx0VRUjCGL3aAqTdcA130_assertion description "[The X-DING-CD4-mediated inhibition of the IL-8 promoter also resulted in a reduction of the soluble IL-8 protein in endothelial cells and human macrophages infected with a subset of enteric bacteria frequently causing diarrhea in progressive HIV disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288583.RAcZNGtW-4rCDRRs0JkTSwoQb8Kjx0VRUjCGL3aAqTdcA130_provenance.
- NP288585.RAenPjIVV-CRjrV1prb7lDO-bDCzlTrkazVn9paeKcJNU130_assertion description "[Taken together, the high levels of thrombin in BAL fluid and its demonstrated mitogenicity for lung fibroblasts suggest an important role for thrombin in the pathogenesis of SSc and perhaps other fibrotic lung diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288585.RAenPjIVV-CRjrV1prb7lDO-bDCzlTrkazVn9paeKcJNU130_provenance.
- NP288586.RAcoL9xNfaoV1ZGehC1Ot-uh0EmTjofZu810aEA1NKoIw130_assertion description "[Hyperglycemia upregulated mRNA levels of fibronectin, laminin β1, collagen IVα3, and vascular endothelial growth factor (VEGF), and this increase was prevented by insulin therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288586.RAcoL9xNfaoV1ZGehC1Ot-uh0EmTjofZu810aEA1NKoIw130_provenance.
- NP288587.RAR6UWEcAWQ8uboj6G1VbFn2aYC3ZZhUmqmO1w3Vp5Zk8130_assertion description "[These results suggest that MRP4 will be a useful prognostic marker for neuroblastoma and that clinical trials of irinotecan as a neuroblastoma treatment should monitor MRP4 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288587.RAR6UWEcAWQ8uboj6G1VbFn2aYC3ZZhUmqmO1w3Vp5Zk8130_provenance.
- NP288590.RARh81ZPg7FSbIfli6Tb5Sh-mWnPe4ECcCO6Z3e2Z3350130_assertion description "[Eotaxin-1/CCL11, eotaxin-2/CCL24, and eotaxin-3/CCL26 bind specifically and exclusively to CC chemokine receptor (CCR) 3, which is a potential therapeutic target in treating the peribronchial eosinophilia associated with allergic airway diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288590.RARh81ZPg7FSbIfli6Tb5Sh-mWnPe4ECcCO6Z3e2Z3350130_provenance.
- NP288595.RAQ3446AkVchj5xEP3YycxT4rcyiIef19IOI8WxG_yWg0130_assertion description "[HOX11, a divergent homeodomain-containing transcription factor, was isolated from the breakpoint of the nonrandom t(10;14)(q24;q11) chromosome translocation found in human T cell acute lymphoblastic leukemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288595.RAQ3446AkVchj5xEP3YycxT4rcyiIef19IOI8WxG_yWg0130_provenance.
- NP288597.RAVIis-nOpNOFgLQ2b6r_1izf5TL4yTLH9e7J5ew4T5xQ130_assertion description "[We conclude that ACME is not necessary for virulence in rodent models of CA-MRSA USA300 pneumonia or skin infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288597.RAVIis-nOpNOFgLQ2b6r_1izf5TL4yTLH9e7J5ew4T5xQ130_provenance.
- NP288599.RAfN1VHLZlvOUs3HOENS4pTqCeQgiuwkT4xiPhDnVw1cE130_assertion description "[This study was conducted to investigate the feasibility of using endoscopic biopsy samples of esophageal squamous cell cancer (ESCC) for comprehensive gene expression profiling (GEP).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288599.RAfN1VHLZlvOUs3HOENS4pTqCeQgiuwkT4xiPhDnVw1cE130_provenance.
- NP288600.RAQnSOXnClnn5cECFOGMWZeQkxGjYhnaMjxVvSA2m-Js4130_assertion description "[While these malformations are believed to result from the effects of TSC1 or TSC2 gene mutations, the molecular mechanisms leading to tuber formation, as well as the onset of seizures, remain largely unknown.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288600.RAQnSOXnClnn5cECFOGMWZeQkxGjYhnaMjxVvSA2m-Js4130_provenance.
- NP288601.RAUbfNAB5B5qA3hnZidEHMaWzQhW0AdNAApqShlRmMHtw130_assertion description "[H19 is an imprinted gene that demonstrates maternal monoallelic expression in fetal tissues and in some cancers, and very likely does not code for a protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288601.RAUbfNAB5B5qA3hnZidEHMaWzQhW0AdNAApqShlRmMHtw130_provenance.
- NP288605.RAT0AU0fI7ekcta3Qoys97-_iSuZCdWg19mCU3_6y7j1k130_assertion description "[In an attempt to understand the mechanism by which serum- or IGF-1-activated JNK induces SHP1 expression resulting in suppression of cell proliferation, we reveal for the first time that in serum- or IGF-1-stimulated breast cancer MCF-7 cells, JNK induces SHP1 expression through the binding of AP-4 and RFX-1 transcription factors to the epithelial tissue-specific SHP1 promoter.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288605.RAT0AU0fI7ekcta3Qoys97-_iSuZCdWg19mCU3_6y7j1k130_provenance.
- NP288609.RAeCtsuHvO5HvWHwPsR9yO9zrPgpAzKQaNInMQDcbGTXY130_assertion description "[Here we report a locus for dominant deafness, DFNA36, which maps to human chromosome 9q13-21 in a region overlapping the DFNB7/B11 locus for recessive deafness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288609.RAeCtsuHvO5HvWHwPsR9yO9zrPgpAzKQaNInMQDcbGTXY130_provenance.
- NP288610.RAW8XvgYKaIpjaBS0ESWbjufg5O3obH3Vxklu4BCm3FRk130_assertion description "[A non-radioactive in situ hybridization method for IL-2 mRNA detection based on the use of four biotinylated oligonucleotide probes, plus appropriate positive and negative control probes was developed and applied to synovial surgical and needle biopsies from rheumatoid arthritis (RA), spondyloarthropathy (SpA), psoriatic arthritis (PsA) and juvenile chronic arthritis (JCA) patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288610.RAW8XvgYKaIpjaBS0ESWbjufg5O3obH3Vxklu4BCm3FRk130_provenance.
- NP288622.RAfc79SS7XCe6aA3DFUOzELyz6Ow0pk8atTrlGMKD4srY130_assertion description "[Moreover, upon treatment with the hypoxia-mimicking desferrioxamine, we demonstrated a decrease in HLA-G gene expression in melanoma FON and choriocarcinoma JEG-3 cell lines, both expressing constitutively HLA-G.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288622.RAfc79SS7XCe6aA3DFUOzELyz6Ow0pk8atTrlGMKD4srY130_provenance.
- NP288628.RASuo-oQZWGObrtLnrKeuQrStMAPEanxZGRD0aqHDEmuk130_assertion description "[Abrogation of Jak1 and Jak2 activity by transient transfection of C4HD cells with dominant negative (DN) Jak1 or DN Jak2 vectors, or inhibition of Src activity by preincubation of cells with the Src family kinase inhibitor PP2, blocked the capacity of MPA to induce Stat3 phosphorylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288628.RASuo-oQZWGObrtLnrKeuQrStMAPEanxZGRD0aqHDEmuk130_provenance.
- NP288630.RAaOMU2Ftfhgcad4mg_jhzl57LFQbeyfjH6gP3XhoAzG0130_assertion description "[These strategies (TRICOM/diversified prime and boost/GM-CSF) were combined to treat CEA-expressing carcinoma liver metastases in CEA-transgenic mice; vaccination was initiated 14 days posttumor transplant.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288630.RAaOMU2Ftfhgcad4mg_jhzl57LFQbeyfjH6gP3XhoAzG0130_provenance.
- NP288633.RARdKhJmMDGK-AK5Tw_3PHmntbwuf6BIZaqTAnkCeH3js130_assertion description "[Transient hyperlipidemia during treatment of ALL with L-asparaginase is related to decreased lipoprotein lipase activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288633.RARdKhJmMDGK-AK5Tw_3PHmntbwuf6BIZaqTAnkCeH3js130_provenance.
- NP288637.RAbCz0Nt9B_-u2HMlfWbOBw4QiZyfN9JrWQPJ4ca49Dys130_assertion description "[Recent findings suggest the involvement of the MET oncogene, encoding the tyrosine kinase receptor for hepatocyte growth factor, in the onset and progression of basal-like breast carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288637.RAbCz0Nt9B_-u2HMlfWbOBw4QiZyfN9JrWQPJ4ca49Dys130_provenance.
- NP288639.RAXwdobDm9KMA2Z7LRcZLnMLwf7bU1iN0OeUeXyy5UZM0130_assertion description "[Furthermore, the PKC activator phorbol 12-myristate 13-acetate (PMA), but not its analog 4α-phorbol 12, 13-didecanoate (4α-PDD), suppressed TRPC6 expression, and this PMA effect was not affected by catalase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288639.RAXwdobDm9KMA2Z7LRcZLnMLwf7bU1iN0OeUeXyy5UZM0130_provenance.
- NP288640.RAb2574ukqaC3EeoEr_r5UpZyI7lEFxHa-9B1MSmGp2Js130_assertion description "[Neuropathological characterization of the ub-ir NII in this family shows that they are positive for promyelocytic leukaemia protein (PML) and SUMO-1 that suggests that these inclusions form in the nuclear body and suggests a possible mechanism of neurodegeneration in tau-negative FTD linked to chromosome 17q21.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288640.RAb2574ukqaC3EeoEr_r5UpZyI7lEFxHa-9B1MSmGp2Js130_provenance.
- NP288643.RAcnyZ6chqza_U8Fca9sEgia1-x_aERUIJu_ej5Jzz4xQ130_assertion description "[We show that the activated epidermal growth factor receptor (EGFR) and the cancer-specific constitutively active EGFR type III deletion mutant (EGFRvIII) induce the expression of EphA2 in mammalian cell lines, including the human cancer cell lines A431 and HN5.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288643.RAcnyZ6chqza_U8Fca9sEgia1-x_aERUIJu_ej5Jzz4xQ130_provenance.
- NP288653.RAZ4U6mcz7MMiGhpiJsnMRJFR4FqBKF7MKhhKqI2W4BM8130_assertion description "[Finally, we applied APL-OSA to a family study of age-related macular degeneration, where cigarette smoking was used as a covariate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288653.RAZ4U6mcz7MMiGhpiJsnMRJFR4FqBKF7MKhhKqI2W4BM8130_provenance.
- NP288655.RAQHUQg5ia8NoGK4RM5BqwRUMWxRqfhWCkSyaTUOC-zFk130_assertion description "[We show here that tERG expression induces PIM1 in the non-malignant prostate cell line RWPE-1, strengthening the relation between tERG and PIM1 up-regulation in the initial stages of prostate carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288655.RAQHUQg5ia8NoGK4RM5BqwRUMWxRqfhWCkSyaTUOC-zFk130_provenance.
- NP288656.RAfTd3o_dFpvYug_XVq8VzXdFSiBbtB0TKLhy8ZFyIC1Y130_assertion description "[We report the lack of megaloblastic anaemia in a patient with severe methionine synthase deficiency who is also homozygous for C677T in MTHFR, hypothesize that the MTHFR polymorphism protects the patient against anaemia and speculate that homozygosity for MTHFR C677T could cause the dissociation between haematological and neurological disease seen in some patients with vitamin B12 deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288656.RAfTd3o_dFpvYug_XVq8VzXdFSiBbtB0TKLhy8ZFyIC1Y130_provenance.
- NP288658.RAXLidOKMP8dCV3EfWQZ00edAx7SL8ZYHlLVAAX_-zQqI130_assertion description "[Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288658.RAXLidOKMP8dCV3EfWQZ00edAx7SL8ZYHlLVAAX_-zQqI130_provenance.
- NP288660.RAQWp4nZiCj0MZDPL4wJRcr19wU1sOjLnXPKNlqiMRqBM130_assertion description "[The non-tumorigenic HeLa x fibroblast cell hybrid CGL1 and the normal diploid fibroblast WI38 expressed the 50-55 kDa GLUT1, whereas in a tumorigenic segregant hybrid, CGL4, as well as in parental HeLa cells, GLUT1 glycosylation was altered and its molecular mass was about 70 kDa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288660.RAQWp4nZiCj0MZDPL4wJRcr19wU1sOjLnXPKNlqiMRqBM130_provenance.
- NP288666.RAYrrSRlNp8F5Sj6AojW8FtWc5TDTzmkibbIN7gsZrCa4130_assertion description "[In vivo, a recent work analyzed the prognostic role of CLU in NSCLC, showing that CLU-positive patients with lung cancer had a better overall survival and disease-free survival than those with CLU-negative tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288666.RAYrrSRlNp8F5Sj6AojW8FtWc5TDTzmkibbIN7gsZrCa4130_provenance.
- NP288671.RAeAWhv9aroNJaCXEIjHjtAAWbbXFxJX936JBBMqvenbM130_assertion description "[On the contrary, genes that decreased upon WT1 inhibition were mainly related to defense against apoptosis, cell cycle, and tumor progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288671.RAeAWhv9aroNJaCXEIjHjtAAWbbXFxJX936JBBMqvenbM130_provenance.
- NP288675.RAcfhyw2OBdXhfXJ0DkAgCkK3Z5_mzEDe4rs6akxBGjcc130_assertion description "[The use of previously established sequence matrices for the scoring of putative ESE motifs showed that the adjacent silent and missense mutations are located within highly conserved overlapping stretches of seven nucleotides with a close similarity to the ESE-specific consensus sequences recognised by the SC35 and SF2/ASF SR proteins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288675.RAcfhyw2OBdXhfXJ0DkAgCkK3Z5_mzEDe4rs6akxBGjcc130_provenance.
- NP288681.RAf0DVjnDS2N81pMPqjdxlH5xYL9vatuP_jRpXU4mStfo130_assertion description "[Estrogen receptor alpha-351 XbaI*G and -397 PvuII*C-related genotypes and alleles are associated with higher susceptibilities of endometriosis and leiomyoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288681.RAf0DVjnDS2N81pMPqjdxlH5xYL9vatuP_jRpXU4mStfo130_provenance.
- NP288684.RAQt_xccaGddZUsV465iw7JPmqT9Lgi-K6txyAm4qTrEo130_assertion description "[Fluorescent polymerase chain reaction (PCR) was used to assay 12 microsatellite markers (APC x 2, DCC, P53 x 2, RB1, NM23, WT1, D6S260, D6S262, D6S281 and TNFa) to look for evidence of microsatellite instability in 40 cases of follicle centre cell lymphoma (FCC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288684.RAQt_xccaGddZUsV465iw7JPmqT9Lgi-K6txyAm4qTrEo130_provenance.
- NP288687.RARTr2K8Az0_8wfRbeAMRETEOgUla4E9E9VUZ30tHxv1M130_assertion description "[Of particular interest is therapy for KS, breast cancer, melanoma, and other cancers in which integrin alpha(v)beta3 is expressed on both angiogenic endothelial cells and tumor cells, which would allow a dual antiangiogenic and antitumor strike with a single drug.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288687.RARTr2K8Az0_8wfRbeAMRETEOgUla4E9E9VUZ30tHxv1M130_provenance.
- NP288690.RAaNC-9wym4bOGALLCplLi0iiclOSg03SYgnv4W9wbUF0130_assertion description "[ID, microcephaly, epilepsy, and language delay are the more specific features associated with DYRK1A abnormalities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288690.RAaNC-9wym4bOGALLCplLi0iiclOSg03SYgnv4W9wbUF0130_provenance.
- NP288692.RAR3LXpdfJxq1ga-Dk6a27Nw9Ip9p6kQT5crA9tx7DVT4130_assertion description "[Several studies have shown that deficiency of C4A is associated with systemic lupus erythematosus (SLE), rheumatoid arthritis and scleroderma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288692.RAR3LXpdfJxq1ga-Dk6a27Nw9Ip9p6kQT5crA9tx7DVT4130_provenance.
- NP288693.RAZ98u8OAh6ZD1ckehfF04trQWW2_HuWrs0cMnxQwQUww130_assertion description "[In contrast, HCV-specific CD8(+) T cells in acute infections evolving to chronicity expressed low levels of CD127 and Bcl-2, exhibited diminished proliferation and cytokine production, and eventually disappeared from the periphery.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288693.RAZ98u8OAh6ZD1ckehfF04trQWW2_HuWrs0cMnxQwQUww130_provenance.
- NP288694.RAWW-eK67RR5vcctXtKYXT8aXugE8dCqJHnAVJWJd7BvA130_assertion description "[The purpose of this study was to identify the adenomatous polyposis coli (APC) tumor suppressor gene mutation and level of wild-type p53 protein expression in patients with oral submucous fibrosis (OSF).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288694.RAWW-eK67RR5vcctXtKYXT8aXugE8dCqJHnAVJWJd7BvA130_provenance.
- NP288697.RAXXuWDjQE1hMTTvQcY4csqoMlqA9ht6oXGu786nZcaF8130_assertion description "[The human lung adeno-carcinoma SPC-A-1 cell line was used as parental cells for developing of highly metastatic cells by in vivo selection in NOD/SCID mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288697.RAXXuWDjQE1hMTTvQcY4csqoMlqA9ht6oXGu786nZcaF8130_provenance.
- NP288698.RAQS1Xvpkp5fz-xFdfVHCcSIK0lvHUthV5kMBDafIjYSA130_assertion description "[Mutations in TRPP2 (polycystin-2) cause autosomal dominant polycystic kidney disease (ADPKD), a common genetic disorder characterized by progressive development of fluid-filled cysts in the kidney and other organs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288698.RAQS1Xvpkp5fz-xFdfVHCcSIK0lvHUthV5kMBDafIjYSA130_provenance.
- NP288700.RATc23k0zpTAjIxlbacqUuyeR0ytrNrPf2E8e5kZDChvw130_assertion description "[To devise an effective method for detecting mutations in 12 genes (CA4, CRX, IMPDH1, NR2E3, RP9, PRPF3, PRPF8, PRPF31, PRPH2, RHO, RP1, and TOPORS) commonly associated with autosomal dominant retinitis pigmentosa (adRP) that account for more than 95% of known mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288700.RATc23k0zpTAjIxlbacqUuyeR0ytrNrPf2E8e5kZDChvw130_provenance.
- NP288709.RAZ9u8JGHPF_vSsyYn5nysr3Q-3SLVfvvs5dZjO0s-MFs130_assertion description "[However, infiltration of leukocytes and MPO activity in the lungs and pancreas during acute pancreatitis was decreased in S100A9-deficient mice and associated with significantly lower serum amylase and lipase activities as well as reduced intrapancreatic TAP-levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288709.RAZ9u8JGHPF_vSsyYn5nysr3Q-3SLVfvvs5dZjO0s-MFs130_provenance.
- NP288710.RAeOvWLay2nQrDe8ovGO5R_OCOzj9S6Pvhs3Pi0YClwbY130_assertion description "[Neurodegeneration with brain iron accumulation (NBIA) involves several genetic disorders, two of which, aceruloplasminemia and neuroferritinopathy, are caused by mutations in genes directly involved in iron metabolic pathway, and others, such as pantothenate-kinase 2, phospholipase-A2 and fatty acid 2-hydroxylase associated neurodegeneration, are caused by mutations in genes coding for proteins involved in phospholipid metabolism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288710.RAeOvWLay2nQrDe8ovGO5R_OCOzj9S6Pvhs3Pi0YClwbY130_provenance.
- NP288711.RATM38Ao5ENC1nCr5vS5tv202l7rrFtAJaQSrFFMOywLE130_assertion description "[Atypical Rothmund-Thomson syndrome in a patient with compound heterozygous mutations in RECQL4 gene and phenotypic features in RECQL4 syndromes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288711.RATM38Ao5ENC1nCr5vS5tv202l7rrFtAJaQSrFFMOywLE130_provenance.
- NP288713.RAZraqHlt7REWUYU_jQLy1cmcF9cZYqt0lypoajouuVu8130_assertion description "[Conversely, only the high OA group showed a significant inhibition of IGF-1 production when PGE2 synthesis was reduced with Naproxen, a non-steroidal antiinflammatory drug (NSAID) that inhibits cyclooxygenases (COX).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288713.RAZraqHlt7REWUYU_jQLy1cmcF9cZYqt0lypoajouuVu8130_provenance.
- NP288718.RAWU8AukcVd8PGDO3b3F6Oq0H_yHYWzgNs7TxHkslhil8130_assertion description "[The aim of this study was to evaluate the presence and the role of the serum soluble costimulatory molecule CD28 in patients with systemic lupus erythematosus (SLE), primary Sjögren's syndrome (SS), and systemic sclerosis (SSc).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288718.RAWU8AukcVd8PGDO3b3F6Oq0H_yHYWzgNs7TxHkslhil8130_provenance.
- NP288726.RAUrmU2ZqsfwXczu0F8NazVh4Itvp5h-D3OVJ6VgbQZHQ130_assertion description "[This study is the first to assess associations of TPH gene variants with IBS-related GI symptoms and stool characteristics.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288726.RAUrmU2ZqsfwXczu0F8NazVh4Itvp5h-D3OVJ6VgbQZHQ130_provenance.
- NP288727.RAY38blh2xI1uQNsDXhasIWd2rQUAx1XLZzck8gxBn_28130_assertion description "[We found that XLA-DC normally differentiate from monocyte precursors and mature in response to lipopolysaccharide (LPS) as assessed by de novo expression of CD83, up-regulation of MHC class II, B7.1 and B7.2 molecules as well as interleukin (IL)-12 and IL-10 production.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP288727.RAY38blh2xI1uQNsDXhasIWd2rQUAx1XLZzck8gxBn_28130_provenance.