Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP292321.RAZq6QwSknd3liJko4Wy9HCk_2cXWyKGK69FD_R6rPVVY130_assertion description "[Taken together, the results of our study suggest that the transcriptional silencing of DLC-1, by epigenetic mechanism, may be involved in gastric carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292321.RAZq6QwSknd3liJko4Wy9HCk_2cXWyKGK69FD_R6rPVVY130_provenance.
- NP292323.RAetV3B502aiZ3QftkcyP_JqFvu9gaxYWP5kRTN3mO2hk130_assertion description "[In the study presented here, we examined the incidence of mutations in the ras gene family and the p53 gene in CCCs of both Japanese and Thai patients by single-strand conformation polymorphism and direct sequencing analyses and compared the pattern of p53 mutation between these two CCC groups.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292323.RAetV3B502aiZ3QftkcyP_JqFvu9gaxYWP5kRTN3mO2hk130_provenance.
- NP292325.RAWRHA54xAqHbfZSuelC6IfeZb2pLV-oh_LYubnuwTJfQ130_assertion description "[Our analysis identified families with heterozygous, deleterious mutations in the DNA repair genes FANCC and BLM, which are responsible for the autosomal recessive disorders Fanconi Anemia and Bloom syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292325.RAWRHA54xAqHbfZSuelC6IfeZb2pLV-oh_LYubnuwTJfQ130_provenance.
- NP292326.RAUfXqUTBeY77H93TdajaBh0Pmzmkbqfoo3jqbRIpetnY130_assertion description "[IGF-1 proved to be a possible predictive factor for resistance to anti-EGFR monoclonal antibodies in K-RAS wild type colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292326.RAUfXqUTBeY77H93TdajaBh0Pmzmkbqfoo3jqbRIpetnY130_provenance.
- NP292328.RAbspEh8LO-8bVI-Kj3mms7hRoS7bUu5nP0dkqp4PK9s0130_assertion description "[However, recently released exome data make some of the prior associations of BrS with genes SCN3B, MOG1, and KCND3 less likely.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292328.RAbspEh8LO-8bVI-Kj3mms7hRoS7bUu5nP0dkqp4PK9s0130_provenance.
- NP292330.RAeq8kP-btgT1hbMtcRJaCJMdg3_GBtq2P08pmb5rJdJc130_assertion description "[Autocrine and paracrine loops between cancer cells and macrophages promote lymph node metastasis via CCR4/CCL22 in head and neck squamous cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292330.RAeq8kP-btgT1hbMtcRJaCJMdg3_GBtq2P08pmb5rJdJc130_provenance.
- NP292335.RAQOLbFsYQ043tzaUE3WpVDzL7Be2XBB2CLnIVBarMSjo130_assertion description "[Mutation analysis of the optineurin gene in familial amyotrophic lateral sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292335.RAQOLbFsYQ043tzaUE3WpVDzL7Be2XBB2CLnIVBarMSjo130_provenance.
- NP292342.RAQzYC631Jt1T7BvC_eQpcNkCi2Xvr_6uDY0vovBPSKLo130_assertion description "[Epidermal growth factor receptor independently predicted improved disease-free interval in adeno/BAC (p = 0.03; hazard ratio, 0.47; 95% confidence interval, 0.23 to 0.94).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292342.RAQzYC631Jt1T7BvC_eQpcNkCi2Xvr_6uDY0vovBPSKLo130_provenance.
- NP292347.RAUPzveWhFX8Hojs2FpidFj2POZY9IzV-m17Z3XHLBi0U130_assertion description "[We have studied a male patient with significant developmental delay, growth failure, hypotonia, girdle weakness, microcephaly, and multiple congenital anomalies including atrial (ASD) and ventricular (VSD) septal defects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292347.RAUPzveWhFX8Hojs2FpidFj2POZY9IzV-m17Z3XHLBi0U130_provenance.
- NP292352.RAbNo1Az2NM4Pmh-lz6b_XjrEbevMLf1SIHk6CJ83DLoA130_assertion description "[Moreover, AID expression was also induced in response to the T helper cell 2-driven cytokines interleukin-4 and interleukin-13, which are activated in human inflammatory bowel disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292352.RAbNo1Az2NM4Pmh-lz6b_XjrEbevMLf1SIHk6CJ83DLoA130_provenance.
- NP292369.RAdV5lyt6_9n-2vm2yJshY9n5rBQmdSJ3hPbCiT6szZtU130_assertion description "[In prostate cancer the secreted form of clusterin (sCLU) has been described as an anti-apoptotic protein whose expression is increased after therapeutic intervention, whereas, the nuclear protein form nCLU was reported to have pro-apoptotic properties.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292369.RAdV5lyt6_9n-2vm2yJshY9n5rBQmdSJ3hPbCiT6szZtU130_provenance.
- NP292372.RATXvfXQxcxaujLC1zG-prl8fKl0cpAaz_7K-pe7fYcgs130_assertion description "[We determined HFE genotypes of 68 male patients with PCT.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292372.RATXvfXQxcxaujLC1zG-prl8fKl0cpAaz_7K-pe7fYcgs130_provenance.
- NP292376.RAe1TcxHL0DxXvvzCp7vRiwyZ_Bz3LFqaaAkKFBp39aKk130_assertion description "[IL-6 could be a CD8(+) proliferation and differentiation agent, an autocrine proteolysis-inducing factor of damaged myotubes, and a proliferation-stimulating agent for satellite cells to replace the destroyed myofibers in IBM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292376.RAe1TcxHL0DxXvvzCp7vRiwyZ_Bz3LFqaaAkKFBp39aKk130_provenance.
- NP292383.RAeo2Az_bc8i5QhDyQ2BkLTERLVkaVaDLs4ml6Qr40u8g130_assertion description "[Treatment with the PAD inhibitor, Cl-amidine, reduced the abundance of deiminated-histone 3, consistent with inhibition of PAD activity, and significantly reduced apoptosis and tissue loss following injury at E15.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292383.RAeo2Az_bc8i5QhDyQ2BkLTERLVkaVaDLs4ml6Qr40u8g130_provenance.
- NP292384.RAUXyUHHgD6R5lxxqrFUlODbDH4qR_BFkVg8wsMzzIqOE130_assertion description "[These results suggest that the MPO -463A allele significantly contributes to a protective effect overall and in smokers against lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292384.RAUXyUHHgD6R5lxxqrFUlODbDH4qR_BFkVg8wsMzzIqOE130_provenance.
- NP292388.RARaRmjb3kJ4yFHpX3_CcVQhqYEONOShq8Pb3VeckgidU130_assertion description "[Albumin-TRS in conjunction with retroviral vector might be used in limited cases such as HCCs with no AFP expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292388.RARaRmjb3kJ4yFHpX3_CcVQhqYEONOShq8Pb3VeckgidU130_provenance.
- NP292393.RASH2v2YxKia1VMosVsgCpUC19fBzrFy9pxbtSDj6lLFE130_assertion description "[In this study, we investigated the mRNA expression of seven Notch-related genes, Notch1/2/3, Hes1/2/3, and Hath1, and then compared it with the expression of gastric mucin genes, MUC5AC and MUC6, in eight gastric cancer (GC) cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292393.RASH2v2YxKia1VMosVsgCpUC19fBzrFy9pxbtSDj6lLFE130_provenance.
- NP292399.RAdmgP4fsfblaVW7cf_gv3jy_w6yz9mP5se5CAHMbGCro130_assertion description "[Forty-nine primary retinoblastoma (Rb) tumors were analyzed by the use of comparative genomic hybridization (CGH), and clinical/histological correlations were performed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292399.RAdmgP4fsfblaVW7cf_gv3jy_w6yz9mP5se5CAHMbGCro130_provenance.
- NP292400.RAcyYPC1BkFnYlpOfwZLsnF30JBfFP6YI-r0_YxbfvRjg130_assertion description "[We tested DNA from 15 centrally infected cases of iatrogenic Creutzfeldt-Jakob disease (CJD) (dura mater or corneal homografts and stereotactic EEG electrodes), 11 peripherally infected cases (native human growth hormone or gonadotrophin), and 110 control individuals for the presence of mutations in the chromosome 20 amyloid gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292400.RAcyYPC1BkFnYlpOfwZLsnF30JBfFP6YI-r0_YxbfvRjg130_provenance.
- NP292403.RAeRX0lFzPiM_OWsBe-zA220BevyeohXHzAWcvgcOc-Bc130_assertion description "[In this regard, we hypothesize that abnormal regulation of hypothalamic-pituitary-adrenal function in UDPF lowers expression of DbetaH protein, which could in turn alter the ratio of dopamine and norepinephrine in noradrenergic neurons, thereby promoting development of psychotic symptoms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292403.RAeRX0lFzPiM_OWsBe-zA220BevyeohXHzAWcvgcOc-Bc130_provenance.
- NP292404.RAaODeHmrp2ZE9R2Huj6EmKt3YgbFp3vAUTyr9KgriIKo130_assertion description "[Serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (T) levels were 36.3 ± 14.0 IU/L, 15.8 ± 6.7 IU/L, and 3.2 ± 2.0 ng/ml in Klinefelter syndrome, and 20.8 ± 10.4 IU/L, 8.2 ± 5.2 IU/L and 4.1 ± 1.5 ng/ml in other sex-chromosome abnormalities, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292404.RAaODeHmrp2ZE9R2Huj6EmKt3YgbFp3vAUTyr9KgriIKo130_provenance.
- NP292405.RAZ7FezkCf1kGDDVcsGY87s7wdAy_EP7hmTe3X3E7I_5M130_assertion description "[A series of bioinformatic analyses identified TNFRSF14-MMEL1 at the 1p36 locus and IKZF3-ORMDL3-GSDMB at the 17q12 locus as the genes most likely associated with RA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292405.RAZ7FezkCf1kGDDVcsGY87s7wdAy_EP7hmTe3X3E7I_5M130_provenance.
- NP292409.RAX8w_76m7KJG_GIN9s9Q3XJfagK3-ltf4XcpS55edZHk130_assertion description "[A haplotype of -1195G, -765G and 8160A alleles was associated with a modest increase in the risk (adjusted odds ratio [OR] 1.38, 95% confidence interval [CI] 0.99-1.91), and the increase was more evident for distal adenomas (adjusted OR 1.57, 95% CI 1.04-2.38).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292409.RAX8w_76m7KJG_GIN9s9Q3XJfagK3-ltf4XcpS55edZHk130_provenance.
- NP292417.RAVb7mbt_JQEm8Ac6qn1EEWrP0-gRMxgmou1rmVcMNsac130_assertion description "[Here we show that human melanomas express inducible T-cell costimulator ligand (ICOS-L/B7H) that can provide costimulation through ICOS for the expansion of activated Tregs maintaining high Foxp3 and CD25 expression as well as a suppressive function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292417.RAVb7mbt_JQEm8Ac6qn1EEWrP0-gRMxgmou1rmVcMNsac130_provenance.
- NP292423.RAXdoKysg0jmvAgYnMFHp1qAhY8yMM24W5clYRHwn_QNo130_assertion description "[The downregulation of IRF4 in CML samples was predominantly found in T cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292423.RAXdoKysg0jmvAgYnMFHp1qAhY8yMM24W5clYRHwn_QNo130_provenance.
- NP292426.RARCwRW4aZzmsRrzo-CLXV9v96_7JDoLEe2SLINQ83qng130_assertion description "[The transcription factor, signal transducer and activator of transcription 3 (Stat3), is constitutively activated in multiple tumors, and aberrant Stat3 activation is linked to the promotion of growth and desensitization of apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292426.RARCwRW4aZzmsRrzo-CLXV9v96_7JDoLEe2SLINQ83qng130_provenance.
- NP292428.RARMv1W0G4rxel2bBqBqukxtPW8H4UsBj9PwpcD22o_yo130_assertion description "[Peptidase A (Pep A) activity assigned to chromosome 18q23 was biochemically examined in fibroblasts cultured from two patients with trisomy 18 and in fibroblasts derived from normal individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292428.RARMv1W0G4rxel2bBqBqukxtPW8H4UsBj9PwpcD22o_yo130_provenance.
- NP292429.RARFEeh6W5w2m3jTqZjHxgqUQVSWtIVZR36_nuxR8P2Go130_assertion description "[One had moderate [clinical dementia rating (CDR = 2], 2 had mild dementia (CDR = 1), and 2 had possible dementia (CDR = 0.5).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292429.RARFEeh6W5w2m3jTqZjHxgqUQVSWtIVZR36_nuxR8P2Go130_provenance.
- NP292430.RAabgAkbNhafCXPGlEyua0rqTfB68Np_hm1B_U7bu09AU130_assertion description "[Hypermethylation of the MLH1 promoter DNA was not evident in sections of normal colon from 10 people with no history of colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292430.RAabgAkbNhafCXPGlEyua0rqTfB68Np_hm1B_U7bu09AU130_provenance.
- NP292431.RAeDGlMtk_OiJxHutfWIt4cZGNtO6TXtzhNX4skqOcGeU130_assertion description "[This study was designed to compare the efficacy and safety of thymosin-alphal (T-alpha1) with that of interferon-alpha (IFN-alpha) in patients with chronic hepatitis B who were positive for hepatitis B virus (HBV) DNA and hepatitis B envelope antibody (anti-HBe).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292431.RAeDGlMtk_OiJxHutfWIt4cZGNtO6TXtzhNX4skqOcGeU130_provenance.
- NP292432.RATAtyLZNDSlq5fqkRui8W-iB2x4cwLCrrcn0AO0TLd5U130_assertion description "[We found an estimated BC HR of 0.89 (95% CI 0.65-1.12, P=0.25) and 1.11 (95% CI 0.81-1.52, P=0.53) for the null alleles of GSTM1 and GSTT1, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292432.RATAtyLZNDSlq5fqkRui8W-iB2x4cwLCrrcn0AO0TLd5U130_provenance.
- NP292434.RAed0LRIeZ5TekH-Pq1e5uZRVEQJJ5pZy1bIX4B9AzeDA130_assertion description "[Insulin resistance is frequently associated with acanthosis nigricans and hyperandrogenism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292434.RAed0LRIeZ5TekH-Pq1e5uZRVEQJJ5pZy1bIX4B9AzeDA130_provenance.
- NP292437.RAbJgGNGSgsA2z_ad6oDZmDP62lxCz728gHjTCQXwX1EY130_assertion description "[Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292437.RAbJgGNGSgsA2z_ad6oDZmDP62lxCz728gHjTCQXwX1EY130_provenance.
- NP292440.RAesnVkeBUfubR6aa_fnvj-KrDIrnZWmb5jScn87qug2M130_assertion description "[Although distinct pathologies, BPH and PCa are both characterized by extensive stromal remodeling, in particular fibroblast-to-myofibroblast differentiation, thought to be induced by elevated local production of TGFβ1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292440.RAesnVkeBUfubR6aa_fnvj-KrDIrnZWmb5jScn87qug2M130_provenance.
- NP292444.RAd0OySITB6loWFRyKqXA5tzELNnu_d1qxqhhoQaEpm98130_assertion description "[ARH should be considered in cases of severe hypercholesterolaemia with a pattern of recessive inheritance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292444.RAd0OySITB6loWFRyKqXA5tzELNnu_d1qxqhhoQaEpm98130_provenance.
- NP292451.RAajBR8TomWgBfVPzweCovlqu-NgGJdLK-7Th3Ojbxc2M130_assertion description "[A variable number of tandem repeats (VNTR) polymorphism in the promoter of PTTG1IP, pituitary tumor transforming gene binding factor targeted by estrogen receptor α (ERα) in endocrine neoplasia, has been shown to be functional, but its relevance to cancer etiology was unknown.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292451.RAajBR8TomWgBfVPzweCovlqu-NgGJdLK-7Th3Ojbxc2M130_provenance.
- NP292452.RAXkrV2mocaxesf3-bZnSPygRnPhnRnlZWIwaGDutWZ-c130_assertion description "[HPV DNA was found either by ViraPap or PCR in 45 of 63 (71%) biopsy specimens, and 37 of 38 (97%) HPV-positive CIN, including the low-grade CIN I variant, contained oncogenic HPV types.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292452.RAXkrV2mocaxesf3-bZnSPygRnPhnRnlZWIwaGDutWZ-c130_provenance.
- NP292453.RAcdHvTZfGd75dj9kEqFhPeIbUnd8b54UdHOSn8OMGB90130_assertion description "[FAK and its homolog Proline-rich tyrosine kinase 2 (Pyk2) modulate paxillin activation; however, their role in regulating IGF-IR-dependent signaling and motility in bladder cancer has not been established.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292453.RAcdHvTZfGd75dj9kEqFhPeIbUnd8b54UdHOSn8OMGB90130_provenance.
- NP292455.RAcGEHJXeFW2jeRPLzSCFA31KwGHIf4cNz_escOevs16Y130_assertion description "[Upstream transcription factor 1 (USF1) has been associated with familial combined hyperlipidemia, the metabolic syndrome, and related conditions, but the mechanisms involved are unknown.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292455.RAcGEHJXeFW2jeRPLzSCFA31KwGHIf4cNz_escOevs16Y130_provenance.
- NP292463.RAYj5UzRSyWzSIc9GoRcdb2dhfeHO7ByP-ffGD8U-tEeY130_assertion description "[PARP expression was 4-fold lower in prednisolone, vincristine and L-asparaginase (PVA)-resistant compared with PVA-sensitive ALL patients (P < .001).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292463.RAYj5UzRSyWzSIc9GoRcdb2dhfeHO7ByP-ffGD8U-tEeY130_provenance.
- NP292464.RAREzoLMY_FsItyQTqpdl4avqHe9-rBiG3jCN6tf5ziuw130_assertion description "[COL4A3, COL4A4, and COL4A5 are the only collagen genes that have been implicated in inherited nephropathies in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292464.RAREzoLMY_FsItyQTqpdl4avqHe9-rBiG3jCN6tf5ziuw130_provenance.
- NP292469.RAV_1u-fyWZ-WtPBLoTkd7DUkNUevTtSQVpIZJ1C12-3M130_assertion description "[ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292469.RAV_1u-fyWZ-WtPBLoTkd7DUkNUevTtSQVpIZJ1C12-3M130_provenance.
- NP292475.RAfx5tRonKXaDmez_PvBPt46mh-OFBrYD_iMGXsvTkAqI130_assertion description "[Polymorphisms in the TP53 tumor suppressor gene and HRAS1 proto-oncogene have been associated in some studies with this cancer; we sought to replicate these associations in an ethnically diverse population in Hawaii.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292475.RAfx5tRonKXaDmez_PvBPt46mh-OFBrYD_iMGXsvTkAqI130_provenance.
- NP292476.RAVe9N_a7KClMV_wbsm560TRnpsY-bny5n1i-ZZ8B1V7E130_assertion description "[We discuss in detail findings in GSF from three historical patients with AIS, which include identification of novel mechanisms of AR malfunction, and the potential ability to utilize HCA for personalized treatment of patients affected by this condition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292476.RAVe9N_a7KClMV_wbsm560TRnpsY-bny5n1i-ZZ8B1V7E130_provenance.
- NP292481.RAfN24MtpexXbyYQrnwW3GDfu-JyCZtKVbYZZ86fzKrFU130_assertion description "[The human nuclear receptor liver receptor homolog-1 (LRH-1) has an important role in controlling lipid and cholesterol homeostasis and is a potential target for the treatment of diabetes and hepatic diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292481.RAfN24MtpexXbyYQrnwW3GDfu-JyCZtKVbYZZ86fzKrFU130_provenance.
- NP292489.RAVdOPSI_aRr3idixrDJe_3YYCAb4dDnNWMWx4jEaVGRw130_assertion description "[Increased level of interleukin-8 (IL-8) and CXCR2 on tumours and in the tumour microenvironment has been associated with CRC growth, progression and recurrence in patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292489.RAVdOPSI_aRr3idixrDJe_3YYCAb4dDnNWMWx4jEaVGRw130_provenance.
- NP292499.RAdUxMY4aNvjIWaB4xNYMTbouzwD7MbAoI61feG-3TUL0130_assertion description "[PCDH19 sequencing analysis was performed in 116 females with various epilepsies, including 97 with Dravet syndrome (83.6%).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292499.RAdUxMY4aNvjIWaB4xNYMTbouzwD7MbAoI61feG-3TUL0130_provenance.
- NP292504.RAQwXTQ_RV4BnH09TWYyk7lcm2otnu4tIh9jj6iWqVaq4130_assertion description "[One individual with familial defective apolipoprotein B-100 (Arg3500Gln) was found in each group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292504.RAQwXTQ_RV4BnH09TWYyk7lcm2otnu4tIh9jj6iWqVaq4130_provenance.
- NP292505.RARmGgrXrody3xZW9VFyuNXddK5EatUB7BUyKASNBhYWQ130_assertion description "[The current study aimed to determine the impact of VEGFA gene single-nucleotide polymorphisms (SNPs) on the risk of aGVHD after allogeneic stem cell transplantation (SCT).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292505.RARmGgrXrody3xZW9VFyuNXddK5EatUB7BUyKASNBhYWQ130_provenance.
- NP292516.RAVwSdgl7aIuS3K2ECxf8xhS4OWJW493pJLcf3j7TEgwU130_assertion description "[While most of our understanding of immune dysfunction in dialysis patients involves alterations in CD28-CD80/86 signalling, nothing is known of CD46-mediated co-stimulation of T cells in these patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292516.RAVwSdgl7aIuS3K2ECxf8xhS4OWJW493pJLcf3j7TEgwU130_provenance.
- NP292522.RAYoihr349bTGu0A9gEbmsU0LZH0foCUBSB1IAT55ypb0130_assertion description "[Her son's axial length was shortened with refractive errors of +16.75 dioptres in the right and +14.0 dioptres in the left eye; ERG evidenced a rod-cone dystrophy, OCT showed central macular thickening with cystoid changes and ultrasonography revealed optic disc drusen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292522.RAYoihr349bTGu0A9gEbmsU0LZH0foCUBSB1IAT55ypb0130_provenance.
- NP292524.RARjbaaGF75Ypz9Gv3hz-JOWdakKIZ01jF8lm46Km6siE130_assertion description "[It was previously reported that hnRNP A2/B1 was overexpressed at the early clinical stage of lung cancer, and that hnRNP B1 protein, a splicing variant of hnRNP A2 mRNA, was elevated in lung cancer tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292524.RARjbaaGF75Ypz9Gv3hz-JOWdakKIZ01jF8lm46Km6siE130_provenance.
- NP292525.RAUdluQoXSOXQiAPDUO-HfVv74LmpG2Od30qqsbIiAi8U130_assertion description "[GCNT2 expression is also significantly correlated to the metastatic phenotype in breast tumor samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292525.RAUdluQoXSOXQiAPDUO-HfVv74LmpG2Od30qqsbIiAi8U130_provenance.
- NP292529.RAQHZynQ_ONtu-0bhO1NwOi_4uwf21Z9JoECKmfp_PUEk130_assertion description "[Increased IgG2a Ab titer in the sera of tumor-free animals after vaccination and elevated CD4(+) CD25(+) regulatory T cells in the PBL of tumor-bearing animals suggested that IFN-gamma-producing Th1 cells may be responsible for partial protection of CD4(+) T cells against the mammary tumor challenge, whereas CD4(+)CD25(+) regulatory T cells (Th2 cells) may suppress the antitumor immune responses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292529.RAQHZynQ_ONtu-0bhO1NwOi_4uwf21Z9JoECKmfp_PUEk130_provenance.
- NP292530.RAb8coYeYumAqK0EC6qB7te-NdLlpyBgOrHlqzWCX_P0Y130_assertion description "[Our results suggest that both red hair colour (RHC) and non-red hair colour variants, and possibly other rare non-synonymous variants, in MC1R are implicated in the development of MM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292530.RAb8coYeYumAqK0EC6qB7te-NdLlpyBgOrHlqzWCX_P0Y130_provenance.
- NP292531.RATZi1auZYU8-PZ2DKnwTJia9RUYJnNFaqu8kw2Uf3xeU130_assertion description "[Our data suggest that inhibition of soluble VEGFR-1 expression represents a novel mechanism--an estrogen-driven angiogenic switch--possibly responsible for breast carcinoma progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292531.RATZi1auZYU8-PZ2DKnwTJia9RUYJnNFaqu8kw2Uf3xeU130_provenance.
- NP292534.RAX4a4vXguIdma7zrZTxJexX6ugqYNVDYOL5XfKOdsvNg130_assertion description "[New type RS1 elements RS1(cla) and RS1(env), and a CTX(env) with rstR(env) and the classical ctxB were identified on the large chromosome of the Mozambican isolates collected in 2005.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292534.RAX4a4vXguIdma7zrZTxJexX6ugqYNVDYOL5XfKOdsvNg130_provenance.
- NP292538.RAdKbZatakzty6UyuiRsTRBlIfoUgpr1yozsKZl4EW3zU130_assertion description "[We have observed evidence of association between the X-linked AT2 (-1332 G/A) polymorphism and premature CAD with further evidence of a statistically significant association with stenotic atherosclerosis requiring revascularization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292538.RAdKbZatakzty6UyuiRsTRBlIfoUgpr1yozsKZl4EW3zU130_provenance.
- NP292545.RAatPPTuKQzix0ZNzC8t85lOK5LMaQwLdPcaiNqqb-NR0130_assertion description "[Polyalanine expansion in the ZIC3 gene leading to X-linked heterotaxy with VACTERL association: a new polyalanine disorder?]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292545.RAatPPTuKQzix0ZNzC8t85lOK5LMaQwLdPcaiNqqb-NR0130_provenance.
- NP292546.RAbwNExZyhLCzU_Nu0D7jp3ky3rMiU0bFPwOqWe-yRIgo130_assertion description "[Tetraspan myelin protein PMP22 and demyelinating peripheral neuropathies: new facts and hypotheses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292546.RAbwNExZyhLCzU_Nu0D7jp3ky3rMiU0bFPwOqWe-yRIgo130_provenance.
- NP292548.RASdkxuLr-nSwWuN4RlPtsKGeeY5hunaMRFd8X2-_yzZQ130_assertion description "[The loss of heterozygosity (LOH) in tumour suppressor gene loci such as p53, retinoblastoma (rb) and adenomatous polyposis coli (apc) were analyzed in oral cancer tissues with matched controls by employing polymerase chain reaction based/restriction fragment length polymorphism (PCR-RFLP), variable number of tandem repeats (PCR-VNTR) analysis and microsatellite assay.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292548.RASdkxuLr-nSwWuN4RlPtsKGeeY5hunaMRFd8X2-_yzZQ130_provenance.
- NP292549.RAR8iYWbGbIRtz5O2rGjW-q7g2T4X6z7fDfOG-quAg7Ak130_assertion description "[In an attempt to define chromosomal alterations that are associated with the metastatic phenotype, we investigated a total of 29 metastasizing (pN+) and 19 non-metastasizing (pN0) head and neck squamous cell carcinomas by comparative genomic hybridization (CGH).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292549.RAR8iYWbGbIRtz5O2rGjW-q7g2T4X6z7fDfOG-quAg7Ak130_provenance.
- NP292551.RAY2A7JfiCeNXJaCS4MSldk5IYNrvOIDunvLa3KeaUbYw130_assertion description "[A CA repeat polymorphism, in the IGF1 gene, which is located 969 bp upstream from the transcription start site and the rs2854744 and rs2854746 single nucleotide polymorphisms (SNPs) in the IGFBP3 gene have been associated with the serum levels of the respective proteins and colorectal cancer (CRC), but the results are inconsistent.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292551.RAY2A7JfiCeNXJaCS4MSldk5IYNrvOIDunvLa3KeaUbYw130_provenance.
- NP292563.RAWMeYcB9BYxEqm5lHLfM0O4-QacwzZ8QpPnX0upyhKk0130_assertion description "[To investigate the impact of different angiogenic micro-environments on EDB-FN expression, we used a tumour model in which human endometrial adenocarcinoma Tet-FGF2 cells overexpressing fibroblast growth factor-2 (FGF2) driven by the tetracycline-responsive promoter were further transfected with a VEGF antisense cDNA, generating AS-VEGF/Tet-FGF2 cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292563.RAWMeYcB9BYxEqm5lHLfM0O4-QacwzZ8QpPnX0upyhKk0130_provenance.
- NP292566.RAa5Uuszwv644HZRg0JeKgotLml2U_HGixQMhkwtU_9_k130_assertion description "[Effect of polymorphisms in XPD, RAI, ASE-1 and ERCC1 on the risk of basal cell carcinoma among Caucasians after age 50.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292566.RAa5Uuszwv644HZRg0JeKgotLml2U_HGixQMhkwtU_9_k130_provenance.
- NP292568.RAdjVd6WWkFcWfFY3ipXlbmhwRfvWAS7K9urtH7w8rYrI130_assertion description "[Therefore, prorenin-receptor blockers, which competitively bind to the receptor as a decoy peptide, have superior benefits with regard to proteinuria and glomerulosclerosis in experimental animal models with elevated plasma prorenin levels such as diabetes and hypertension compared with conventional RAS inhibitors, possibly by inhibiting both the nonproteolytic activation of prorenin and RAS-independent intracellular signals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292568.RAdjVd6WWkFcWfFY3ipXlbmhwRfvWAS7K9urtH7w8rYrI130_provenance.
- NP292569.RAcSSj1Q4W-TgxoxT_rizj2AUBA4nYelOpz102jyoHyFo130_assertion description "[Insulin-like growth factor II overexpression, a common genetic alteration of adrenocortical carcinomas, was significantly correlated with higher VEGF-A and lower TSP1 concentrations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292569.RAcSSj1Q4W-TgxoxT_rizj2AUBA4nYelOpz102jyoHyFo130_provenance.
- NP292573.RAWfN8Tx-yeIgXXkBZJbvJWn960blXOG0nK0aMo-Z5fE4130_assertion description "[Mutational analysis of SKP2 and P27 in Chinese Han women with premature ovarian failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292573.RAWfN8Tx-yeIgXXkBZJbvJWn960blXOG0nK0aMo-Z5fE4130_provenance.
- NP292577.RAUw3hy7HXzzSliWIKIZBRiM2P9pmczmVauLg8wMVSSkc130_assertion description "[Increasing evidence indicates that the activated type I IFN system in lupus is critical in the etiopathogenesis of the disease and is an important therapeutic target.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292577.RAUw3hy7HXzzSliWIKIZBRiM2P9pmczmVauLg8wMVSSkc130_provenance.
- NP292584.RAdxc0b-CAp35X93Tr-V1BJw15faUAc38tpYtQeT2UdzA130_assertion description "[The present study was designed to analyze more objectively the protein EGFR expression in CCRCC and to compare its value with EGFR gene copy number changes and clinicopathologic characteristics including patient survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292584.RAdxc0b-CAp35X93Tr-V1BJw15faUAc38tpYtQeT2UdzA130_provenance.
- NP292586.RAe3Hj-YaPfpBYb5ymgxJgCuOcv-OXl_0yi3XgneONtUA130_assertion description "[An RHDV-VLP, modified to contain the universal helper T cell epitope PADRE and decorated with an MHC I-restricted peptide (aa 48-57) from the HPV16 E6, was tested for its immunotherapeutic efficacy against the TC-1 HPV16 E6 and E7-expressing tumour in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292586.RAe3Hj-YaPfpBYb5ymgxJgCuOcv-OXl_0yi3XgneONtUA130_provenance.
- NP292589.RAQwmqZJ9E0fRxLlEC1QgPmlrNP0m7JdcyMOihZFrQiLU130_assertion description "[Profound obesity associated with a balanced translocation that disrupts the SIM1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292589.RAQwmqZJ9E0fRxLlEC1QgPmlrNP0m7JdcyMOihZFrQiLU130_provenance.
- NP292593.RAeKt_-2Iy7P19CwcM-L1FaLZxgS8GutZYaeVLjdhV_68130_assertion description "[Soluble P-selectin and vascular endothelial growth factor in steady state sickle cell disease: relationship to genotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292593.RAeKt_-2Iy7P19CwcM-L1FaLZxgS8GutZYaeVLjdhV_68130_provenance.
- NP292594.RAXYnSFsafeVUmINpbuTBBxENwoajk1Pb7RTlC6qqduSg130_assertion description "[Amyloid plaque density, congophilic amyloid angiopathy (CAA), and neurofibrillary tangle (NFT) density scores were based on CERAD criteria and compared in apolipoprotein E (APOE) e4 carriers (n=42) and noncarriers (NC) (n=137).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292594.RAXYnSFsafeVUmINpbuTBBxENwoajk1Pb7RTlC6qqduSg130_provenance.
- NP292596.RAaA4xIyLapelj-bzrmGTZopGYBVSP-anOuE3ZsssZx1o130_assertion description "[In addition, the localization of ET-1 mRNA observed in astrocytomas suggests a role for ET-1 in tumour pathogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292596.RAaA4xIyLapelj-bzrmGTZopGYBVSP-anOuE3ZsssZx1o130_provenance.
- NP292598.RAdN06EDrmsu4U8_D-2OZW4nb2yjPkmSkHc5dix1_O98o130_assertion description "[Pyrosequencing analysis of 150 paired primary gastric cancer samples revealed that promoter CpG methylation was increased in 74% of tested tumors compared with paired adjacent normal tissues, and this hypermethylation correlated significantly with down-regulation of CCDC67.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292598.RAdN06EDrmsu4U8_D-2OZW4nb2yjPkmSkHc5dix1_O98o130_provenance.
- NP292600.RAY3ma5CUk_Qk6ITGV6j152caaABvClBTegJqxdTB4neA130_assertion description "[PPK of Sybert is characterized by palmoplantar hyperkeratosis with transgrediens, autosomal dominant inheritance, and the absence of associated systemic features.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292600.RAY3ma5CUk_Qk6ITGV6j152caaABvClBTegJqxdTB4neA130_provenance.
- NP292606.RAdww0OBKh8OAYQgZZj5xFp6yp26l7WWmXY3SM8v_9YPQ130_assertion description "[More than 85% of patients with severe sepsis have low levels of protein C. Absolute levels of protein C correlate with morbidity and mortality outcomes of the sepsis population, regardless of age, infecting microorganism, presence of shock, disseminated intravascular coagulation, degree of hypercoagulation, or severity of illness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292606.RAdww0OBKh8OAYQgZZj5xFp6yp26l7WWmXY3SM8v_9YPQ130_provenance.
- NP292608.RAdO5gxHSJvavG4C5XJaf8lpbI6V9qnOs8rMU1mkx4yLA130_assertion description "[Epidermal growth factor (EGF) receptor (EGFR) mutations are the best illustration of the therapeutic relevance of identifying such molecular clusters of lung cancer based on driver genetic alterations that predict the efficacy of specific tyrosine kinase inhibitors, a strategy referred to as `personalized medicine.` Besides EGFR and ALK, other genes harboring driver molecular alterations have been identified as part of integrated genomic studies of lung cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292608.RAdO5gxHSJvavG4C5XJaf8lpbI6V9qnOs8rMU1mkx4yLA130_provenance.
- NP292610.RAVjxysvH2vO4n4Jemn7YegaBgcPmmgxV2ZsJVObe9tFY130_assertion description "[Our data confirms that the angiotensin I converting enzyme genotypes can influence the phenotypic expression of hypertrophy and shows that this influence depends on the mutation, raising the concept of multiple genetic modifiers in familial hypertrophic cardiomyopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292610.RAVjxysvH2vO4n4Jemn7YegaBgcPmmgxV2ZsJVObe9tFY130_provenance.
- NP292619.RAQJY57wf9HgoosZ6r6nAJlm7HELv21F8pcckdL4KrNUo130_assertion description "[A chimeric gene, MSP-Fu(24), was constructed by genetically coupling immunodominant, conserved regions of the two leading malaria vaccine candidates, Plasmodium falciparum merozoite surface protein 1 (C-terminal 19-kDa region [PfMSP-1(19)]) and merozoite surface protein 3 (11-kDa conserved region [PfMSP-3(11)]).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292619.RAQJY57wf9HgoosZ6r6nAJlm7HELv21F8pcckdL4KrNUo130_provenance.
- NP292622.RAdkrIcm7vuHL2Afox7WEAhGLsgvAKpEVf3Mgp5zdSVmA130_assertion description "[GST pull-down results clearly demonstrated that SARS_N protein could directly and specifically bind to human hnRNP A1 in vitro.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292622.RAdkrIcm7vuHL2Afox7WEAhGLsgvAKpEVf3Mgp5zdSVmA130_provenance.
- NP292623.RAYJQSazhIESkofDLElu3AHMdKplP7BLoY3g_vJBRd0iQ130_assertion description "[Acquired mutations in ATRX are observed in the preleukemic condition alpha thalassemia myelodysplastic syndrome (ATMDS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292623.RAYJQSazhIESkofDLElu3AHMdKplP7BLoY3g_vJBRd0iQ130_provenance.
- NP292624.RAfzEyHkF_wY6vClMj5466QQELa1bK-Xs4AyLxj-5Zey8130_assertion description "[The Val/Val, Val/Ala genotypes and the Val allele of the MTS were found predominantly but the Ile/Ile genotype and the Ile allele of the exon-3 were detected in patients with cervical cancer, breast cancer and healthy women in Thailand.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292624.RAfzEyHkF_wY6vClMj5466QQELa1bK-Xs4AyLxj-5Zey8130_provenance.
- NP292628.RAUE2lAJ57e-_0HnBLUzgq90rsHoPToEzkkDCjMik9GaY130_assertion description "[9L gliosarcoma cells transduced with the CPA-activating enzyme couple P450 2B6/P450 reductase and grown s.c. in immunodeficient severe combined immunodeficient (scid) mice were repeatedly challenged with 140 mg/kg CPA every 6 days.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292628.RAUE2lAJ57e-_0HnBLUzgq90rsHoPToEzkkDCjMik9GaY130_provenance.
- NP292630.RAVW7-A-0LQOgP_juCgHV0topln_IezJvpjFzMC3MfaV0130_assertion description "[Apolipoprotein B (apoB) is associated with MetS by multiple logistic analysis with an OR of 1.05 (1.03-1.07, P<0.001) in FCHL families, OR of 1.26 (1.03-1.55, P=0.026) in FHTG and OR of 1.07 (1.01-1.12, P=0.014) in FH families, independent of variables including age, gender, apolipoprotein A1, and low density lipoprotein cholesterol.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292630.RAVW7-A-0LQOgP_juCgHV0topln_IezJvpjFzMC3MfaV0130_provenance.
- NP292633.RAWfs0DgX_qH4o-7FvuZda11btywhRUI402e4GkZJ8wa8130_assertion description "[To study the pattern of aspirin-induced urticaria (AIU) in two families, with special interest on the polymorphisms of LTC4S (AA, AC, CC) and the glutathione S-transferase M1 and P1 genes (GSTM1 and GSTP1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292633.RAWfs0DgX_qH4o-7FvuZda11btywhRUI402e4GkZJ8wa8130_provenance.
- NP292634.RAfRhF2QNRUEJ12c5Z6Lo0gp0H11Zi9gTsOIWMruo8pSY130_assertion description "[We determined the diagnosis of hereditary hemorrhagic telangiectasis (HHT) in a suspected HHT family, identified ALK1 gene mutation and established a gene diagnosis method of HHT.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292634.RAfRhF2QNRUEJ12c5Z6Lo0gp0H11Zi9gTsOIWMruo8pSY130_provenance.
- NP292640.RAS4Iouqj20fHwzHUk3rO40cm6QZZYuOoUseVNOBZjUYk130_assertion description "[Additionally, mRNA of the full-length leptin receptor OB-R and of the short isoforms B219.1-B219.3 was identified in granulosa cells and the CL, as well as in the cortex and medulla.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292640.RAS4Iouqj20fHwzHUk3rO40cm6QZZYuOoUseVNOBZjUYk130_provenance.
- NP292641.RAaaO4cfcS9qsWobTQOjta9WpyoDDZCilapLW5A3vESLY130_assertion description "[Knowledge that mutations in the RET proto-oncogene cause MTC and studies documenting genitourinary abnormalities in RET or GDNF knockout mice led us to examine the GDNF/RET-GDNFR alpha signaling complex in this family.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292641.RAaaO4cfcS9qsWobTQOjta9WpyoDDZCilapLW5A3vESLY130_provenance.
- NP292642.RAbA7yCBeEiKsUBWnttOQ_z5-CIqOh3ws5X3_Q7Hp4dSc130_assertion description "[We investigated p53 and its downstream effectors p21WAF1/CIP1, BAX, and hMSH2 as well as the proliferation marker Ki-67 (mki-67/MIB-1) in patients undergoing preoperative radiochemotherapy for rectal carcinoma to identify prognostic and predictive factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292642.RAbA7yCBeEiKsUBWnttOQ_z5-CIqOh3ws5X3_Q7Hp4dSc130_provenance.
- NP292661.RAXtn2c6zAXw-Tkcf8M3HG8-jx_a4zXFAs8tEMtWtB9n8130_assertion description "[Cystic fibrosis (CF) is a multisystem autosomal recessive disorder caused by mutations of the cystic fibrosis transmembrane regulator (CFTR), a protein that regulates cyclic-AMP-mediated chloride conductance at the apical membrane of secretory epithelia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292661.RAXtn2c6zAXw-Tkcf8M3HG8-jx_a4zXFAs8tEMtWtB9n8130_provenance.
- NP292665.RAXQSCV9UMitY2rfVv7jR_UbMnAkZeSvxdADcnlWaM3t8130_assertion description "[In a series of sibpairs with late onset Alzheimer's disease, we have examined the segregation of the loci involved in the early onset, autosomal dominant form of the disorder by using flanking microsatellite repeat markers: thus we have used APP-PCR3 and D21S210 to examine the segregation of the amyloid-beta precursor protein (APP) gene, the markers DI 4S77 and D14S284 to examine the segregation of the presenilin 1 (PSI) gene and the markers D1S227, D1S249 and D1S419 to examine the segregation of presenilin 2 (PS2).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292665.RAXQSCV9UMitY2rfVv7jR_UbMnAkZeSvxdADcnlWaM3t8130_provenance.
- NP292667.RATgMs6CMpIopT2LovTFqWwz-pquoUeMYuLGwtdG3mUPI130_assertion description "[NSCLC patients with at least one susceptible allele of the MspI polymorphism of the CYP1A1 gene [heterozygous genotype B or a rare homozygous genotype C; n = 131; median survival time (MST) = 24.2 months] were associated with a shortened survival compared with those with nonsusceptible homozygous alleles (genotype A; n = 101; MST = 65.2 months; P = 0.005 by log-rank test).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292667.RATgMs6CMpIopT2LovTFqWwz-pquoUeMYuLGwtdG3mUPI130_provenance.
- NP292681.RAZuVvQXhTfo_GWmgoLwL8_0riv1nzgmIIobairFcgRtk130_assertion description "[Our estimates of CRC and EC cumulative risks for MLH1 and MSH2 mutation carriers are the most precise currently available.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292681.RAZuVvQXhTfo_GWmgoLwL8_0riv1nzgmIIobairFcgRtk130_provenance.
- NP292682.RAc0-vpyL4PsZXFJaeN1aESREMRHU7PqBa99-4J4jD65o130_assertion description "[A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292682.RAc0-vpyL4PsZXFJaeN1aESREMRHU7PqBa99-4J4jD65o130_provenance.
- NP292683.RAcGrb2RD0tlVmQyNN44sKRlR6QJXnu_xB8h61aBbDJME130_assertion description "[The insertion (I)/deletion (D) polymorphism of the ACE gene and the M235T polymorphism of the AGT gene were genotyped in 773 nondiabetic individuals with hypertension, 193 normotensive patients with type 2 diabetes, 243 patients with type 2 diabetes and hypertension, and in 820 normotensive control individuals identified in a community-based study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292683.RAcGrb2RD0tlVmQyNN44sKRlR6QJXnu_xB8h61aBbDJME130_provenance.
- NP292692.RARLCiOqp2x3UcZIV1aMshIfjbLwiQHAJqLvonKKJfeSM130_assertion description "[Utilizing a loss of constitutional heterozygosity assay in the B-NHL tumor panel, 24 additional 6q26-q27 polymorphic markers (21 mapping to the contig) further defined RMD-1 between markers D6S186 proximally and D6S227 distally.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292692.RARLCiOqp2x3UcZIV1aMshIfjbLwiQHAJqLvonKKJfeSM130_provenance.
- NP292696.RAbuHcunvN_2vyhPf_VHp7vNItdeAXlWXY1baLWLjKICs130_assertion description "[LINE-1 hypomethylation and AIM1 hypermethylation have prognostic utility in both melanoma patients' tumors and serum.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292696.RAbuHcunvN_2vyhPf_VHp7vNItdeAXlWXY1baLWLjKICs130_provenance.
- NP292697.RAfJWoDo2qrOT0quKqTPfB1zGnKDnfW84MHaoeO6nWAv4130_assertion description "[Here we show that mice with PVH-specific ablation of LIM domain only 4 (Lmo4) become rapidly obese when fed regular chow due to hyperphagia rather than to reduced energy expenditure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP292697.RAfJWoDo2qrOT0quKqTPfB1zGnKDnfW84MHaoeO6nWAv4130_provenance.