Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Five+sequence+variants+found+in+Gilles+de+la+Tourette+syndrome. assertion.
- assertion asSentence The+serotonin+type+6+%285-HT%286%29%29+receptor+is+a+G-protein+coupled+receptor+%28GPCR%29+coupled+to+a+stimulatory+G-protein+%28G%28S%29%29. assertion.
- assertion asSentence Common+variants+in+the+gene+for+HT6R+do+not+contribute+to+obesity. assertion.
- assertion asSentence HTR7+is+a+susceptibility+gene+for+schizophrenia+in+this+Japanese+group. assertion.
- assertion asSentence The+human+Rad9%2FRad1%2FHus1+complex+interacts+with+and+stimulates+DNA+polymerase+beta+activity. assertion.
- assertion asSentence Loss+of+HUS1+sensitizes+cells+to+etopside-induced+apoptosis+by+regulating+BH3-only+proteins. assertion.
- assertion asSentence Rad9-Rad1-Hus1+complex+enhances+in+vitro+activity+of+8-oxoguanine+DNA+glycosylase. assertion.
- assertion asSentence The+HUS1+protein+interacts+with+casein+kinase+2. assertion.
- assertion asSentence Tenascin-C+is+a+beta-catenin+target+gene+in+human+colorectal+tumors. assertion.
- assertion asSentence TGF-beta1+and+eosinophils+dramatically+induced+Tn-C+mRNA+and+protein+expression+in+nasal+epithelial+cells. assertion.
- assertion asSentence EMMPRIN+regulates+migration%2C+MMP+production+by+mouth+cancer+SCC+cells+and+deposition+of+the+TN-C+matrix. assertion.
- assertion asSentence Tumor-cell+expressions+of+alpha9+and+beta1+integrins+in+combination+with+extracellular+tenascin+%28tenascin+C+is+preferential+substrate%29+are+necessary+for+medulloblastoma+adhesion+to+the+leptomeninges. assertion.
- assertion asSentence In+gliomas%2C+the+TNC+gene+is+transactivated+by+Notch2+in+an+RBPJk-dependent+manner+mediated+by+an+RBPJk+binding+element+in+the+TNC+promoter. assertion.
- assertion asSentence Endogenous+TNC+enhances+glioblastoma+invasion+with+reactive+change+of+surrounding+brain+tissue. assertion.
- assertion asSentence Demonstrate+increased+expression+of+tenascin-C+and+alpha-smooth+muscle+actin+positive+cells+in+the+large+airways+in+chronic+obstructive+pulmonary+disease. assertion.
- assertion asSentence Upregulation+of+HYAL1+expression+in+breast+cancer+promoted+tumor+cell+proliferation%2C+migration%2C+invasion+and+angiogenesis. assertion.
- assertion asSentence The+frequency+of+the+S20G+mutation+in+the+amylin+gene+is+1.92%25+in+unrelated+Korean+type+2+diabetic+patients+and+this+mutation+is+associated+with+a+lower+BMI+and+a+higher+HbA%281c%29+level. assertion.
- assertion asSentence Amylin+is+expressed+in+the+human+placenta+and+is+regulated+by+nutritional+status. assertion.
- assertion asSentence Role+of+ICAM-1+in+the+aggregation+and+adhesion+of+human+alveolar+macrophages+in+response+to+TNF-alpha+and+INF-gamma. assertion.
- assertion asSentence ICAM-1+participated+in+cell+attachment+to+X-+and+Y-fragments%2C+rather+than+to+intact+fibrinogen+or+late+degradation+products%2C+fragments+D+and+E. assertion.
- assertion asSentence In+endothelial+cells%2C+ICAM-1+stimulates+c-fos+and+rhoA+transcription+and+up-regulates+rhoA+expression+by+a+positive+feedback+pathway+after+RhoA+activation. assertion.
- assertion asSentence Expression+of+ICAM-1+is+sufficient+to+initiate+a+signal-dependent+adhesion+of+resting+NK+cells+which+can+be+greatly+enhanced+either+by+a+pulse+of+IL-2+or+IL-15%2C+or+by+coexpression+of+LFA-3+or+CD48+with+ICAM-1%2C+even+in+the+absence+of+cytokines. assertion.
- assertion asSentence ICAM-1+is+a+protective+haplotype+against+multiple+sclerosis. assertion.
- assertion asSentence Causal+role+of+in+invasion+of+metastatic+human+breast+carcinoma+cell+lines. assertion.
- assertion asSentence Mutation+of+the+serine+phosphorylation+site+leads+to+inability+of+Mac-1+to+become+activated+to+bind+the+cellular+ligands+ICAM-1+and+ICAM-2. assertion.
- assertion asSentence IL-6+-634C%2FG+and+ICAM-1+469K%2FE+polymorphisms+synergistically+affect+the+susceptibility+for+endometriosis+in+the+Japanese+population. assertion.
- assertion asSentence Tyrosine+phosphorylation+of+cortactin+dynamically+links+ICAM-1+to+the+actin+cytoskeleton%2C+enabling+ICAM-1+to+form+clusters+and+facilitate+leukocyte+transmigration. assertion.
- assertion asSentence Hemoglobin+A1C+in+diabetics+is+positively+associated+with+ICAM1+levels. assertion.
- assertion asSentence Cytokine-induced+endothelial+intercellular+adhesion+molecule-1+and+vascular+cell+adhesion+molecule-1+expressionwas+inhibited+by+tecastemazole+in+a+manner+independent+of+H1+receptor+antagonism. assertion.
- assertion asSentence Increased+blood+levels+in+rheumatoid+arthritis+are+diminished+after+treatment+with+methotrexate. assertion.
- assertion asSentence FasL+and+ICAM-1+expression+in+the+tonsillar+high+endothelial+venules+contribute+to+idiopathic+tonsillar+hypertrophy+and+chronic+hypertrophic+tonsillitis. assertion.
- assertion asSentence Plays+a+nonredundant+role+in+T+cell+receptor-driven+formation+of+transendothelial+protrusion+and+transendothelial+migration. assertion.
- assertion asSentence Treatment+of+K562+cells+with+bortezomib+downregulates+the+expression+of+CAM-1+by+inhibiting+the+activity+of+NF-kappaB. assertion.
- assertion asSentence Interactions+between+rs5498+polymorphism+in+the+ICAM1+gene+and+traditional+risk+factors+influence+susceptibility+to+coronary+artery+disease. assertion.
- assertion asSentence An+important+role+of+PKC-delta+and+PI3K%2FAkt1%2C2+pathways+in+activating+mTOR+as+an+endogenous+modulator+to+ensure+a+tight+regulation+of+NF-kappaB+signaling+of+ICAM-1+expression+in+endothelial+cells. assertion.
- assertion asSentence ICAM-1+%28Lys469Glu%29+and+PECAM-1+%28Leu125Val%29+polymorphisms+in+diffuse+astrocytomas. assertion.
- assertion asSentence Fibrinogen+binding+to+ICAM-1+promotes+mucin+production+by+decreasing+TGF-alpha-induced+EGFR+and+ERK1%2F2+activation. assertion.
- assertion asSentence Compared+with+open+surgery%2C+laparoscopy-assisted+radical+gastrectomy+is+not+associated+with+a+greater+effect+on+the+expression+of+ICAM-1+and+integrin+beta%281%29+in+peritoneal+mesothelial+cells. assertion.
- assertion asSentence Efficient+MTOC+polarization+at+the+virological+synapse+requires+Tax-mediated+stimulation+of+T-cell+activation+pathways+in+synergy+with+ICAM-1+cross-linking. assertion.
- assertion asSentence Both+high+pressure+CO2+and+5%25+dextrose+solution+can+increase+the+expression+of+CD44+and+ICAM-1+in+endometrial+cancer+cells. assertion.
- assertion asSentence GPx-1+modulates+LPS-mediated+up-regulation+of+ICAM-1+and+VCAM-1+mRNA+and+protein+in+endothelial+cells%2C+in+part%2C+by+altering+CD14-mediated+effects. assertion.
- assertion asSentence There+is+not+any+association+between+G241R+or+K469E+polymorphisms+within+the+ICAM-1+gene+and+susceptibility+to+polycystic+ovary+syndrome. assertion.
- assertion asSentence Plasmodium+VIR+proteins+can+specifically+mediate+cytoadherence+to+the+ICAM-1+endothelial+receptor. assertion.
- assertion asSentence An+interplay+between+ICAM-1+and+MLCK-dependent+contractile+forces+mediates+neutrophil+transmigration+through+oxLDL-treated+endothelium. assertion.
- assertion asSentence The+binding+partner+of+DC-SIGN+on+endothelial+cells+is+the+glycan+epitope+Lewis%28Y%29+%28Le%28Y%29%29%2C+expressed+on+ICAM-2. assertion.
- assertion asSentence Receptor+tyrosine+kinase+EphA2+mediates+thrombin-induced+upregulation+of+ICAM-1+in+endothelial+cells+in+vitro. assertion.
- assertion asSentence Id1+has+cell+cycle+regulatory+functions+that+are+similar+to+those+of+c-Myc. assertion.
- assertion asSentence Dysregulates+centrosome+homeostasis+at+least+in+part+by+interfering+with+S5A%2FRpn10+activities+at+the+centrosome. assertion.
- assertion asSentence Id1+can+be+strongly+up-regulated+by+Transforming+Growth+Factor+beta1+in+the+human+mammary+gland+epithelial+cell+line+MCF10A. assertion.
- assertion asSentence High+Id1+expression+is+associated+with+acute+myeloid+leukemia. assertion.
- assertion asSentence ID-1+is+implicated+in+the+pathogenesis+and+progression+of+gastric+cancer. assertion.
- assertion asSentence AMP-activated+protein+kinase+%28PRKAA1%2F2%2C+aka+AMPK%29+mediates+the+stress-induced+proteasome-dependent+loss+of+ID2+at+high+stress+levels. assertion.
- assertion asSentence ID4+drives+brain+tumor-initiating+cell+genesis+through+cyclin+E+and+notch+signaling. assertion.
- assertion asSentence Increased+frequency+of+promoter+hypermethylation+in+ID4+gene+in+acute+myeloid+leukemia+compared+to+chronic+myeloid+leukemia. assertion.
- assertion asSentence Id4+gene+methylation+is+found+in+myelodysplastic+syndrome+patients+with+higher+ratio+of+blast+cells. assertion.
- assertion asSentence The+insulin-dependent+diabetes+mellitus+2+gene+%28IDDM2%29+is+a+type+1+diabetes+susceptibility+locus+contributed+to+by+the+variable+number+of+tandem+repeats+upstream+of+the+insulin+gene. assertion.
- assertion asSentence IDE+is+targeted+to+mitochondria+via+alternative+initiation+of+translation. assertion.
- assertion asSentence Polymorphisms+in+the+IDE-KIF11-HHEX+gene+locus+are+associated+with+susceptibility+to+type+2+diabetes+across+the+boundary+of+race. assertion.
- assertion asSentence In+comparison+to+Abeta40%2C+Abeta42+is+more+flexible+and+interacts+through+a+smaller+number+%2817-22%29+of+hydrogen+bonds+in+the+catalytic+chamber+of+IDE. assertion.
- assertion asSentence Mutations+of+IDH1+is+not+detected+in+brain+metastases+of+colorectal+cancer. assertion.
- assertion asSentence Frequent+IDH1+mutations+in+supratentorial+primitive+neuroectodermal+tumors+of+adults. assertion.
- assertion asSentence IDH1+and+IDH2+mutations+are+associated+glioma+and+acute+myeloid+leukemia+cases. assertion.
- assertion asSentence IDH1+mutations+are+associated+with+acute+myeloid+leukemia. assertion.
- assertion asSentence IDH1+mutation+is+not+associated+with+glioblastoma. assertion.
- assertion asSentence IDH1+mutation+is+associated+with+brain+tumors. assertion.
- assertion asSentence Up-regulation+of+isocitrate+dehydrogenase+1+is+associated+with+non-small+cell+lung+cancer. assertion.
- assertion asSentence Reverse+TCA+cycle+flux+through+isocitrate+dehydrogenases+1+and+2+is+required+for+lipogenesis+in+hypoxic+melanoma+cells. assertion.
- assertion asSentence IDH-1+mutation+is+associated+with+oligodendroglioma. assertion.
- assertion asSentence Some+patients+with+cytogenetically+normal+acute+myeloid+leukemia+and+elevated+2-hydroxyglutarate+possessed+IDH2+mutations. assertion.
- assertion asSentence IDH1+and+IDH2+mutations+are+recurrent+in+de+novo+cytogenetically+normal+acute+myeloid+leukemia+and+have+an+unfavorable+impact+on+outcome. assertion.
- assertion asSentence IDH2+gene+mutation+is+associated+with+blast-phase+myeloproliferative+neoplasms. assertion.
- assertion asSentence IDH2+somatic+mutations+in+chronic+myeloid+leukemia+patients+in+blast+crisis. assertion.
- assertion asSentence IDH2+mutation+is+associated+with+brain+tumors. assertion.
- assertion asSentence High+IDH2+is+associated+with+d-2-hydroxyglutaric+aciduria+type+II. assertion.
- assertion asSentence In+WHO+grade+II+astrocytomas%2C+IDH1%2F2+mutations+mostly+occur+in+tumors+infiltrating+the+frontal+lobe. assertion.
- assertion asSentence An+abnormal+control+of+the+complement+alternative+pathway+is+a+risk+factor+for+the+occurrence+of+HELLP+syndrome. assertion.
- assertion asSentence Increased+levels+of+IFI+16+in+prostate+epithelial+cells+contribute+to+senescence-associated+irreversible+cell+growth+arrest. assertion.
- assertion asSentence Histone+deacetylase-dependent+transcriptional+silencing+of+the+IFI16+gene+in+prostate+epithelial+cells+contributes+to+the+development+of+prostate+cancer. assertion.
- assertion asSentence IFI16+exerts+in+vivo+anti-tumoral+activity+by+promoting+apoptosis+of+tumor+cells. assertion.
- assertion asSentence Both+HIN+domains+of+interferon%2C+gamma-inducible+protein+16+are+capable+of+enhancing+p53-DNA+complex+formation+and+transcriptional+activation+via+distinctive+means. assertion.
- assertion asSentence Dissociation+of+the+IFN-induced+protein+IFP35+from+NMI+is+a+newly+defined+specific+cytoplasmic+event+occurring+during+apoptosis. assertion.
- assertion asSentence A+range+of+mutations+in+SP110+that+cause+decreased+SP110+protein+levels+and+impaired+late+B-cell+differentiation+cause+veno-occlusive+disease+with+immunodeficiency+syndrome. assertion.
- assertion asSentence High+levels+of+serum+IFN-alpha+are+correlated+with+febrile+seizures+in+influenza. assertion.
- assertion asSentence IFN-alpha+alone+is+able+to+induce+the+secretion+of+small+amounts+of+IP-10+in+plasmacytoid+dendritic+cells+and+is+found+to+synergize+with+low+concentrations+of+IFN-gamma%2C+in+a+Th1-like+environment. assertion.
- assertion asSentence Measles+virus+V+protein+blocks+IFN-alpha+by+inhibiting+STAT1+and+STAT2+phosphorylation. assertion.
- assertion asSentence Demdritic+cells+express+and+store+IFN-alpha+in+to+confer+resistance+to+foot+and+mouth+disase+virus. assertion.
- assertion asSentence IFNalpha+activity+and+BAFF+levels+are+elevated+in+the+plasma+of+patients+with+Sjogren%27s+syndrome+compared+with+healthy+controls. assertion.
- assertion asSentence DC-SIGN+enhances+the+production+of+IFN-alpha+and+TNF-alpha+in+cells+that+infected+by+glycosylated+West+Nile+virus. assertion.
- assertion asSentence IFN-alpha+synergizes+with+interleukin+%28IL%29-12+in+regulating+the+development+of+IL-2-secreting+human+T%28central+memory%29+cells. assertion.
- assertion asSentence IFN-alpha+amplifies+the+inductive+effect+of+CpG+ODN+on+naive+B+activation+and+on+Ig+production+through+a+mechanism+involving+TLR-9%2FMyD88-dependent+signaling. assertion.
- assertion asSentence Less+STAT1+methylation+and+subsequent+increased+STAT1-PIAS1+interaction+are+involved+in+the+mechanism+of+the+interferon+alpha-antagonistic+activity+of+hepatitis+B+virus. assertion.
- assertion asSentence Autophagic+responses+play+a+role+in+influenza+virus-induced+CXCL10+and+interferon-alpha+expression+in+primary+human+blood+macrophages. assertion.
- assertion asSentence Through+direct+interaction%2C+C3a+and+CpGA+synergize+to+increase+IFN-alpha+production+in+a+RAGE-dependent+manner+and+stimulate+an+innate+immune+response. assertion.
- assertion asSentence C1q+inhibits+immune+complex-induced+interferon-alpha+production+in+plasmacytoid+dendritic+cells. assertion.
- assertion asSentence Alpha+interferon+suppresses+the+cyclin+D3+and+cdc25A+genes%2C+leading+to+a+reversible+G0-like+arrest. assertion.
- assertion asSentence Alpha+interferon+suppresses+the+cyclin+D3+and+cdc25A+genes%2C+leading+to+a+reversible+G0-like+arrest. assertion.
- assertion asSentence IFNAR1+and+IFNAR2+levels+reveal+that+the+KAS-6%2F1+cell+line+overexpresses+IFNAR1+relative+to+other+myeloma+cell+lines+that+are+growth+arrested+by+IFN-alpha. assertion.
- assertion asSentence Mutation+of+the+IFNAR-1+receptor+binding+site+of+human+IFN-alpha2+generates+type+I+IFN+competitive+antagonists. assertion.
- assertion asSentence Expression+and+kinase+activity+of+PKD2+are+required+for+the+ligand-inducible+stimulation+of+IFNAR1+ubiquitination+and+endocytosis+and+for+accelerated+proteolytic+turnover+of+IFNAR1. assertion.
- assertion asSentence In+cells+exposed+to+VEGF%2C+phosphorylation-dependent+degradation+of+IFNAR1+leads+to+an+inhibition+of+type+1+IFN+signaling+and+is+required+for+efficient+VEGF-stimulated+angiogenesis. assertion.