Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence IKK+beta+phosphorylation+is+involved+in+decoy+receptor+3+expression+in+AsPC-1+pancreatic+adenocarcinoma+cells. assertion.
- assertion asSentence EBNA1+inhibits+the+canonical+NF-kappaB+pathway+in+carcinoma+lines+by+inhibiting+the+phosphorylation+of+IKKalpha%2Fbeta. assertion.
- assertion asSentence Regulatory+subunit+of+PP5+G4-1+functions+as+an+adaptor+to+recruit+PP5+to+the+phosphorylated+C-terminus+of+activated+IKKbeta+and+to+down-regulate+the+activation+of+IKKbeta. assertion.
- assertion asSentence Lipopolysaccharide-mediated+reactive+oxygen+species+and+signal+transduction+in+the+regulation+of+interleukin-1+gene+expression. assertion.
- assertion asSentence Interleukin-1+system+plays+a+role+in+sex+steroid+receptor+gene+expression+in+human+endometrial+cancer. assertion.
- assertion asSentence Association+of+the+interleukin-1+gene+cluster+on+chromosome+2q13+with+knee+osteoarthritis. assertion.
- assertion asSentence IL-1A+allele+2+is+a+risk+factor+for+Alzheimer%27s+disease+%28AD%29+in+a+dose-dependent+manner%2C+the+risk+of+developing+AD+with+two+copies+of+the+IL-1A+allele+2+being+approximately+double+that+of+one+copy+of+the+IL-1A+allele+2. assertion.
- assertion asSentence IL1-alpha+induced+during+in+vitro+activation+of+mast+cells+by+cystic+fibrosis-associated+Pseudomonas+aeruginosa+stimulates+neutrophil+transendothelial+migration. assertion.
- assertion asSentence The+association+of+the+TN7%28delTTCA%29A+haplotype+with+higher+levels+of+IL-1+alpha+expression+and+reduced+risk+for+ESRD+is+consistent+with+involvement+of+cytokines+in+risk+for+developing+nephropathy. assertion.
- assertion asSentence Activation+of+vascular+endothelial+cells+by+IL-1alpha+released+by+a+pulmonary+epithelial+cell+line+infected+with+respiratory+syncytial+virus. assertion.
- assertion asSentence Cancer+cell-derived+cytokines%2C+such+as+IL-1+alpha%2C+induce+cachexia+by+affecting+leptin-dependent+metabolic+pathways. assertion.
- assertion asSentence A+potent+cytokine+stimulus+for+IL-8+RNA+stabilization+in+breast+cancer+cells. assertion.
- assertion asSentence Constitutively+expressed+IL-1alpha+is+critical+for+numerous+interferon-gamma+activities. assertion.
- assertion asSentence Dihydrotestosterone+inhibits+TNF-alpha-induced+IL1A+mRNA+expression+in+rheumatoid+synovial+cells. assertion.
- assertion asSentence In+silico+complete+mRNA+structures+of+the+IL-1alpha+and+IL-1beta+mRNAs+in+humans. assertion.
- assertion asSentence There+is+an+association+between+the+IL-1+polymorphisms+and+chronic+periodontitis. assertion.
- assertion asSentence Colon+cancer+cell-derived+IL-1alpha+up-regulates+angiogenesis+by+modulating+stromal+cells+within+the+tumor+cells%27+microenvironment. assertion.
- assertion asSentence Modulation+of+calprotectin+in+human+keratinocytes+by+keratinocyte+growth+factor+and+interleukin-1alpha. assertion.
- assertion asSentence Conditional+cellular+depletion+and+reconstitution+in+diphtheria+toxin+receptor+transgenic+mice+reveals+that+host+macrophages+play+an+essential+role+in+the+generation+of+the+inflammatory+response+to+cell+death+and+are+the+source+of+the+required+IL-1alpha. assertion.
- assertion asSentence IL-1A+rs3783553+polymorphism+is+associated+with+nasopharyngeal+carcinoma. assertion.
- assertion asSentence Association+between+carriage+of+IL-1+rare+alleles+and+periodontitis+differed+between+Down+and+non-Down+subjects.+carriage+of+IL-1+rare+alleles+in+Down+subjects+tended+to+confer+protective+effect+against+loss+of+periodontal+attachment. assertion.
- assertion asSentence The+polymorphism+of+promotor+region+-31C%2FT+of+IL-1B+gene+is+associated+with+the+susceptibility+of+gastric+cancer+in+Chinese. assertion.
- assertion asSentence Genotype+not+altered+in+MALT+lymphoma. assertion.
- assertion asSentence IL-1beta+polymorphism+influences+the+susceptibility+to+acquire+systemic+lupus+erythematosus. assertion.
- assertion asSentence Glucocorticoids+inhibit+transcription+directed+by+the+IL-lbeta+gene+%28IL1B%29+upstream+induction+sequence+%28UIS%29+enhancer. assertion.
- assertion asSentence IL-6+polymorphism+is+associated+with+age+of+onset+of+type+1+diabetes+only+when+detected+in+patients+with+a+high+IL-1beta+and+tumor+necrosis+factor-alpha+producer+genotype. assertion.
- assertion asSentence Complex+folds+of+IL-1+beta+like+the+beta-trefoil+fold+and+functional+loops+like+the+beta-bulge+can+make+some+of+the+configuration+space+unavailable+to+the+protein+and+cause+topological+frustration. assertion.
- assertion asSentence IL-1beta+and+IL-1Ra+haplotype+influences+the+impact+of+allograft+outcome+in+renal+transplant+patients. assertion.
- assertion asSentence The+IL-1B%2B3954+T+allele+is+a+major+risk+for+cachexia+from+locally+advanced+gastric+cancer. assertion.
- assertion asSentence Inhibition+of+ERK+phosphorylation+decreased+expression+of+IL1B. assertion.
- assertion asSentence IL-1+beta+plus+interleukin-6+enhance+the+binding+of+transcription+factor+C%2FEBPbeta+to+the+C-reactive+protein+promoter+in+Hep3B+tumor+cells. assertion.
- assertion asSentence Variation+in+IL-1beta+promoter+conditions+susceptibility+to+severe+malarial+anemia+and+functional+changes+in+circulating+IL-1beta+levels. assertion.
- assertion asSentence IL1+beta+and+tumor+necrosis+factor+are+important+regulators+of+chorioamnionitis-related+decidual+leukocyte+infiltration+and+activation. assertion.
- assertion asSentence IL-1beta+increases+vascular+cell+adhesion+molecule-1+expression+via+PI-PLC%2FCa2%2B%2FCaM%2FCaMKII%2FHDAC4+and+PI-PLC%2FPKCalpha%2Fc-Src%2FROS%2FNF-kappaB%2C+p300+signaling+pathways+in+human+tracheal+smooth+muscle+cells. assertion.
- assertion asSentence Regulation+of+epithelial-mesenchymal+IL-1+signaling+by+PPARbeta%2Fdelta+is+essential+for+skin+homeostasis+and+wound+healing. assertion.
- assertion asSentence The+constitutive+activation+of+the+PI3K-Akt+pathway+in+Fanconi+anaemia+cells+upregulates+the+expression+of+IL-1beta. assertion.
- assertion asSentence IL1B+single+nucleotide+polymorphisms+are+associated+with+prostate+cancer. assertion.
- assertion asSentence IL-1beta%2C+TNF+and+IP-10+in+the+cerebrospinal+fluid+and+serum+are+not+altered+in+patients+with+idiopathic+intracranial+hypertension+compared+to+controls. assertion.
- assertion asSentence Sterile+trauma+to+normal+human+dermis+invariably+induces+IL1beta%2C+IL6+and+IL8+in+an+innate+response+to+%22danger%22. assertion.
- assertion asSentence IL-1B-511+polymorphism+is+associated+with+increased+risk+of+certain+subtypes+of+gastric+cancer+in+Chinese. assertion.
- assertion asSentence CCAAT%2FEnhancer-binding+protein+%7Bbeta%7D+and+NF-%7Bkappa%7DB+mediate+high+level+expression+of+chemokine+genes+CCL3+and+CCL4+by+human+chondrocytes+in+response+to+IL-1%7Bbeta%7D. assertion.
- assertion asSentence Inhibitors+of+MAPK+pathway+ERK1%2F2+or+p38+prevent+the+IL-1%7Bbeta%7D-induced+up-regulation+of+SRP72+autoantigen+in+Jurkat+cells. assertion.
- assertion asSentence EGFR+and+IL-1+signaling+synergistically+promote+keratinocyte+antimicrobial+defenses+in+a+differentiation-dependent+manner. assertion.
- assertion asSentence Facultative+heterochromatin+%28fHC%29+silences+IL-1beta+expression+during+sepsis. assertion.
- assertion asSentence Children+with+IL-1B-511TT%2F-31CC+have+a+risk+to+develop+severe+gastric+mucosal+histological+changes+in+South+China. assertion.
- assertion asSentence IL-1beta+induces+dedifferentiation+of+articular+chondrocytes+by+up-regulation+of+SIRT1+activity+enhanced+by+both+NAMPT+and+ERK+signaling. assertion.
- assertion asSentence Carriers+of+-511%2F%2B3954+CTCT+are+at+risk+of+developing+functional+pancreatic+neuroendocrine+tumors+%28pNETs%29+%28p%3D0.006%29+and+carriers+of+-511%2F%2B3954+CTCC+are+at+risk+of+developing+nonfunctional+pNETs. assertion.
- assertion asSentence IL-1B+gene+polymorphism+affects+the+modulation+of+serum+oxLDL+levels. assertion.
- assertion asSentence A+functional+polymorphism+in+the+promoter+region+of+the+IL1B+gene+is+associated+with+risk+of+multiple+myeloma. assertion.
- assertion asSentence IL-1ra+is+associated+with+preserved+beta-cell+capacity+in+type+1+diabetes. assertion.
- assertion asSentence Interleukin-1R3+mediates+interleukin-1-induced+potassium+current+increase+through+fast+activation+of+Akt+kinase. assertion.
- assertion asSentence OxLDL+exposure+reduces+the+expression+of+IL1RN. assertion.
- assertion asSentence Anion+competition+for+the+interleukin-1+receptor+antagonist+%28IL-1ra%29+cationic+site+suppresses+IL-1ra+aggregation+via+interference+with+its+self-association+pathway. assertion.
- assertion asSentence Exerts+intracellular+functions+regulating+effect+of+N-terminal+IL-1alpha+propiece+on+movement+of+ECV304+tumor+cells. assertion.
- assertion asSentence IL-1beta+and+IL-1Ra+haplotype+influences+the+impact+of+allograft+outcome+in+renal+transplant+patients. assertion.
- assertion asSentence IL-1Ra+intron+2+polymorphism+plays+a+prominent+role+among+the+IL-1+gene+cluster+with+respect+to+bladder+carcinogenesis. assertion.
- assertion asSentence Carriers+of+the+IL-1-RA+appeared+to+have+an+increased+risk+of+stroke+in+association+with+a+febrile+episode+prior+to+strokes. assertion.
- assertion asSentence IL-1Ra+gene+polymorphism+is+associated+with+lumbar+disc+disease+among+Chinese+population. assertion.
- assertion asSentence Interleukin-1+receptor+antagonist+is+the+earliest+sensitive+marker+of+anti-inflammatory+response+to+enteral+immunonutrition+in+malnourished+patients+after+pancreaticoduodenectomy. assertion.
- assertion asSentence IL-1RN%2A2+allele+carriage+is+associated+with+a+poor+prognosis+of+achieving+a+pregnancy+after+IVF. assertion.
- assertion asSentence Type+I+IFN-induced+IL1RA+expression+in+hepatocytes+is+mediated+by+activating+STAT6+through+the+formation+of+STAT2%3ASTAT6+heterodimer. assertion.
- assertion asSentence The+genetic+polymorphisms+of+interleukin-1beta+and+interleukin-1+receptor+antagonist+are+not+risk+factors+for+OA+etiology+in+Han+Chinese. assertion.
- assertion asSentence Low+levels+of+IL-1RA+are+associated+with+delirium. assertion.
- assertion asSentence Carriers+of+the+two+relatively+frequent+variants+of+the+IL-1b+gene+at+-31+and+-511+position%2C+i.e.+-31TT+and+-511CC%2C+are+at+a+higher+risk+of+developing+coronary+artery+disease+requiring+surgical+treatment+or+two-stage+percutaneous+angioplasty. assertion.
- assertion asSentence IL-1ra+%28R2%3A0.287%2C+P+%3C+.05%29+correlated+with+BMI+in+overweight+adolescents. assertion.
- assertion asSentence Molecular+mechanism+of+NFAT+family+proteins+for+differential+regulation+of+the+IL-2+and+TNF-alpha+promoters. assertion.
- assertion asSentence The+proximal+promoter+region+of+the+IL-2+gene+can+assemble+into+a+rotationally+and+translationally+positioned+mononucleosome+under+chromatin+reconstitution+conditions+in+vitro+and+in+vivo%2C+maintaining+an+inactive+IL-2+gene+in+resting+T+cells. assertion.
- assertion asSentence Nuclear+export+of+NF90+is+required+for+its+interleukin-2+mRNA+stabilization. assertion.
- assertion asSentence Number+of+CD8%2B%2FIL-2+cells+significantly+higher+in+elderly+trained+than+in+elderly+untrained. assertion.
- assertion asSentence IL2+and+GMCSF+do+not+cause+a+cumulative+gain+in+peripheral+dendritic+cell+counts+or+an+increase+in+myeloid+BDCA-1%2B+BDCA-2-+dendritic+cell+subset+in+the+peripheral+blood. assertion.
- assertion asSentence IL-2+induced+regulation+of+Sgk1+and+a+role+of+the+IL-2+receptor+and+Sgk1+in+the+regulation+of+epithelial+tumor+cell+death+and+survival. assertion.
- assertion asSentence IL-2+gene+polymorphisms+in+Chinese+Han+are+significantly+different+from+those+in+Thai%2C+Japanese+and+Spain+ethnic+groups. assertion.
- assertion asSentence Serum+vascular+endothelial+growth+factor+and+fibronectin+predict+clinical+response+to+high-dose+interleukin-2+therapy. assertion.
- assertion asSentence Susceptibility+to+tuberculous+infection+is+associated+with+G+allele+and+TG+and+GG+genotypes+of+T-330G+polymorphism+in+the+IL2+gene. assertion.
- assertion asSentence The+suppressive+capacity+of+regulatory+T+%28Treg%29+cells+critically+depends+on+IL-2+even+when+Treg+cell+survival+is+independent+of+this+cytokine. assertion.
- assertion asSentence Patients+with+infection+and+sepsis+have+deficient+IL-2+and+IL-7+gene+expression+in+peripheral+blood+leukocytes. assertion.
- assertion asSentence iTreg+cells+-+similar+to+recombinant+TGF-beta+and+nTreg+cells+-+inhibited+IL-2-induced+activation+of+NK+cells+in+the+absence+of+target+cell+contact. assertion.
- assertion asSentence IL-2+upregulates+CD86+expression+on+human+CD4%28%2B%29+and+CD8%28%2B%29+T+cells+via+a+receptor-dependent+mechanism+that+involves+the+NFAT+and+mammalian+target+of+rapamycin+pathways. assertion.
- assertion asSentence Regulatory+T+%28Treg%29+cell+division+does+not+absolutely+require+cell-autonomous+transgenic+T+cell+receptor+signaling+in+vivo%2C+depending+on+the+degree+of+IL-2-mediated+stimulation+provided. assertion.
- assertion asSentence IL-2+drives+activated+B+cell+differentiation+toward+plasma+cells+independently+of+its+proliferation+and+survival+functions. assertion.
- assertion asSentence The+mechanics+of+this+complex+receptor+system+and+to+other+receptor+complexes+in+the+immune+system+that+send+signals+by+clustering+receptor+subunits. assertion.
- assertion asSentence Mucosal+induction+of+tolerance+against+dietary+antigens+is+associated+with+the+development+of+CD4%28%2B%29CD25%28%2B%29+T+cells. assertion.
- assertion asSentence Cytomegalovirus+infection+raises+the+IL-2R+level+in+serum+of+childbearing+age+women. assertion.
- assertion asSentence CD4%2B+CD45RO%2B+Foxp3%2B+CD25hi+T+lymphocytes+are+highly+proliferative%2C+with+a+doubling+time+of+8+days%2C+compared+with+memory+CD4%2B+CD45RO%2B+Foxp3-+CD25-+%2824+days%29. assertion.
- assertion asSentence IL-2Ralpha+solely+has+a+prognostic+value+and+should+be+considered+as+a+major+prognostic+factor+for+adult+lymphoblastic+leukemia. assertion.
- assertion asSentence Hepatocellular+carcinoma+cell+supernatants+increase+expansion+and+function+of+IL2RA+of+regulatory+T-cells. assertion.
- assertion asSentence CD4%28%2B%29CD25%28%2B%29IL-7Ralpha%28%2B%29+cell+population+represents+a+specific+marker+to+monitor+allospecific+CD4+T+cell+responses+in+blood+and+in+tissues+after+organ+transplantation. assertion.
- assertion asSentence Allelic+heterogeneity%22+at+the+IL2RA+region+between+Multiple+sclerosis+and+type+1+diabetes. assertion.
- assertion asSentence Single+nucleotide+polymorphisms+in+IL2RA+in+lymphocytes+are+associated+with+diabetes+mellitus. assertion.
- assertion asSentence Prenatal+exposure+to+malaria+blood-stage+antigen+Msp1+induces+CD25-positive+regulatory+T+cells+that+primarily+suppress+T+helper+type+%28Th%291-type+recall+responses. assertion.
- assertion asSentence Demonstrate+an+increase+in+the+proportion+of+CD4%2BCD25highIL-7Ralphahigh+activated+T+cells+in+kidney+transplant+recipients%2C+regardless+of+the+immunosuppressive+regimen. assertion.
- assertion asSentence High+serum+IL-2R+level+is+associated+with+peripheral+T-cell+lymphoma%2C+unspecified. assertion.
- assertion asSentence The+C627T+polymorphism+in+the+IL2RB+gene+is+not+associated+with+risk+of+endometriosis+in+Korean+women. assertion.
- assertion asSentence The+immature+form+of+the+gamma%28c%29+chain+is+a+54-58+kDa+intracellular+component+localized+in+the+endoplasmic+reticulum+of+resting%2C+unstimulated+CD4+T+cells. assertion.
- assertion asSentence Self-sufficient+growth+of+B+lymphoblastoid+cells+in+X-linked+combined+immunodeficiency+disease+%28SCID%29+cell+lines+is+strongly+dependent+on+common+gamma-chain+expression. assertion.
- assertion asSentence IL-2R+common+gamma-chain+is+epigenetically+silenced+by+nucleophosphin-anaplastic+lymphoma+kinase+%28NPM-ALK%29+and+acts+as+a+tumor+suppressor+by+targeting+NPM-ALK. assertion.
- assertion asSentence WEHI-3B-derived+IL-3+stimulation+of+mcl-1+gene+transcription+through+the+SIE+motif+involves+phosphorylation+of+PU.1+at+serine+142+by+a+p38%28MAPK%29-dependent+pathway. assertion.
- assertion asSentence The+IL3+regulates+the+growth+and+differentiation+of+hematopoietic+progenitor+cells+and+functionally+activates+mature+neutrophils+or+macrophages. assertion.
- assertion asSentence Expression+of+CD48+on+human+peripheral+blood+eosinophils+is+regulated+by+interleukin+%28IL%29-3. assertion.
- assertion asSentence Two+different+modes+of+beta+c+binding+are+utilized+in+the+presence+of+the+hIL-3R+alpha+isoforms. assertion.