Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence The+germinal+center+%28GC%29+B+cells+in+tonsils+and+colonic+mucosa+are+a+predominant+source+of+IL-4+and+demonstrate+the+reliance+of+IL-4-dependent+Th2+differentiation+in+vivo+on+strong+B+cell+participation+and+the+development+of+GCs. assertion.
- assertion asSentence IL-4+interfered+with+the+TGF-beta-induced+transcriptional+activation+of+the+CTGF+gene. assertion.
- assertion asSentence Association+of+interleukin-4+and+interleukin-1B+gene+variants+with+Larsen+score+progression+in+rheumatoid+arthritis. assertion.
- assertion asSentence Lack+of+antitumor+activity+and+intolerance+of+this+drug+in+patients+with+advanced+HIV+disease+and+Kaposi%27s+sarcoma. assertion.
- assertion asSentence In+conjunctiva+of+keratoconjunctivitis+sicca+patients. assertion.
- assertion asSentence IL4+is+associated+with+diabetes+mellitus%2C+type+1+in+Filipinos. assertion.
- assertion asSentence The+IL-4+gene+locus+%28-590+C--%3ET+polymorphism+and+70+bp+repeat+polymorphism%29+contributes+little+to+the+interindividual+susceptibility+for+adult+periodontitis+in+a+Korean+population. assertion.
- assertion asSentence Autocrine+production+of+IL-4+and+IL-10+promotes+thyroid+tumor+cell+progression+and+resistance+to+chemotherapy+through+the+up-regulation+of+antiapoptotic+proteins. assertion.
- assertion asSentence IL-4+plays+a+very+important+role+in+both+pathogenesis+of+allergic+rhinitis+and+desensitization+therapy. assertion.
- assertion asSentence Certain+IL-13%2Fl4+haplotypes+associated+with+severe+Respiratory+Syncytial+virus+infection. assertion.
- assertion asSentence IL-4+up-regulates+mitochondrial+adenine+nucleotide+translocase+%28ANT%293+in+human+T+cells. assertion.
- assertion asSentence An+influence+of+genetic+variability+at+the+promoter+of+IL-4+gene+%28-590C%3ET%29+and+a+coding+region+of+IL-13+gene+%28R130Q%29+on+the+occurrence+of+allergic+asthma+and+no+relationship+between+IL-16+promoter+polymorphism+%28-295T%3EC%29+and+this+disease. assertion.
- assertion asSentence Some+cytokine+gene+alleles+reflecte+stable+graft+function+among+kidney+transplant+recipients. assertion.
- assertion asSentence Production+of+human+interleukin-10+%28IL-10%29+and+IL-4+partially+contributed+to+HSV-1-induced+KSHV+replication. assertion.
- assertion asSentence IL-4+gene+polymorphisms+that+arise+at+either+intron+3+or+promoter+-590+positions+are+not+suitable+genetic+markers+for+autoimmune+diseases+of+the+thyroid+gland+among+Taiwanese+Chinese. assertion.
- assertion asSentence The+-590CC+genotype+in+the+IL4+gene+is+a+strong+predictive+factor+for+the+development+of+hypothyroidism+in+Hashimoto+disease. assertion.
- assertion asSentence The+follicular+lymphoma+microenvironment+contains+increased+levels+of+IL-4%2C+with+prominent+tumor+basal+phosphorylation+of+Erk. assertion.
- assertion asSentence Expanded+catalog+of+genetic+loci+implicated+in+psoriasis+susceptibility. assertion.
- assertion asSentence IL-4%2FIL-10+impairs+the+Th1+protective+response+and+allows+the+parasite+to+survive+in+hydatid+patients. assertion.
- assertion asSentence Susceptibility+to+tuberculous+infection+is+associated+with+C+allele+and+CC+and+CT+genotypes+of+C-590T+polymorphism+in+the+IL4+gene. assertion.
- assertion asSentence Increased+IL-4+is+associated+with+multiple+myeloma. assertion.
- assertion asSentence Interleukin-4+increased+CD209+expression+on+human+Schwann+cells+and+subsequent+Schwann+cell+binding+to+Mycobacterium+leprae. assertion.
- assertion asSentence Signals+ensued+by+IFN-alpha+and+IL-4+induce+cytoplasmic+sequestration+of+IL-4-activated+STAT6+and+IFN-alpha-activated+STAT2%3Ap48+in+B+cells+through+the+formation+of+pY-STAT6%3ApY-STAT2%3Ap48+complex. assertion.
- assertion asSentence Interleukin-4+-590T%2FC+polymorphism+influences+the+susceptibility+to+nonsmall+cell+lung+cancer. assertion.
- assertion asSentence Internalization+of+interleukin+4+receptor+alpha+increases+cytotoxic+effect+of+interleukin+4-receptor-targeted+cytotoxin+in+cancer+cells. assertion.
- assertion asSentence IL4R+is+associated+with+diabetes+mellitus%2C+type+1+in+Filipinos. assertion.
- assertion asSentence Tumor+expression+of+IL-4Ralpha+is+inversely+correlated+with+survival+in+patients+undergoing+surgical+resection+for+epithelial+MPM. assertion.
- assertion asSentence Constitutive+overexpression+of+human+IL-5+in+transgenic+mice+induces+migration+of+bone+marrow+progenitor+cells+to+the+spleen+and+extramedullary+hematopoiesis+in+the+spleen. assertion.
- assertion asSentence IL-5+induces+the+protein+expression+of+cyclin+D3+and+the+kinase+Pim-1%2C+both+of+which+are+regulated+by+STAT-dependent+processes+in+airway+and+blood+eosinophils. assertion.
- assertion asSentence IL-5+overexpression+is+associated+with+eosinophilia+in+T-cell+lymphomas. assertion.
- assertion asSentence RgpA-Kgp+proteinase-adhesin+complexes+of+Prophyromonas+gingivalis+degrade+Th2+cytokines+IL-4+and+IL-5+and+reduce+their+bioavailability+in+T+cell+lines. assertion.
- assertion asSentence Interleukin+%28IL%29-6+protein+concentrations+are+increased+approximately+18-fold+in+clinically+localized+prostate+cancers+when+compared+to+normal+prostate+tissue. assertion.
- assertion asSentence Autocrine+production+of+interleukin+6+causes+multidrug+resistance+in+breast+cancer+cells. assertion.
- assertion asSentence The+-597+G--%3EA+and+-174+G--%3EC+polymorphisms+in+the+promoter+of+the+IL-6+gene+are+associated+with+hyperandrogenism. assertion.
- assertion asSentence Reproductive+hormone-induced%2C+STAT3-mediated+interleukin+6+action+in+normal+and+malignant+human+ovarian+surface+epithelial+cells. assertion.
- assertion asSentence Interleukin-6+production+is+induced+in+smooth+muscle+cells+by+monocyte+chemoattractant+protein-1+via+differential+activation+of+nuclear+factor-kappa+B. assertion.
- assertion asSentence The+IL-6+G%28-174%29C+polymorphism+is+not+associated+with+the+risk+of+CAD+or+MI+and+does+not+contribute+to+cardiovascular+risk+stratification. assertion.
- assertion asSentence Interleukin-6+down-regulates+TFF+expression+in+human+stomach+neoplasm+cells+cultivated+in+vitro. assertion.
- assertion asSentence Release+of+IL-6+from+oncostatin+M-stimulated+peritoneal+mesothelial+cells+is+dose-+and+time-dependent+and+contributes+to+the+control+of+leukocyte+recruitment+by+the+soluble+IL-6+receptor. assertion.
- assertion asSentence Bradykinin+induces+IL-6+production+in+human+airway+smooth+muscle+cells. assertion.
- assertion asSentence IL-6+precludes+the+negative+effects+induced+by+IL-3+on+cord+blood+CD34%2B+cell+expansion+and+telomerase+activity. assertion.
- assertion asSentence Constitutive+activation+of+nuclear+factor+kappaB+p50%2Fp65+and+Fra-1+and+JunD+is+essential+for+deregulated+interleukin+6+expression+in+prostate+cancer. assertion.
- assertion asSentence Skeletal+muscle+IL-6+production+is+regulated+by+an+autocrine+mechanism+at+the+transcriptional+level. assertion.
- assertion asSentence IL-6+secreted+by+Mycobacterium+tuberculosis-infected+macrophages+inhibits+the+responses+of+uninfected+macrophages+to+interferon-gamma. assertion.
- assertion asSentence Cyclooxygenase+2+gene+polymorphism+is+associated+with+squamous+cell+carcinoma. assertion.
- assertion asSentence No+difference+in+serum+level+of+normal+and+hemodialysis+or+peritoneal+dialysis+patients. assertion.
- assertion asSentence Expreeeion+of+interleukin-6+in+human+osteoblast-like+cells+is+suppressed+by+arginine-vasopressin. assertion.
- assertion asSentence Secreted+in+cultured+osteoblasts+from+uremia+patients. assertion.
- assertion asSentence The+additive+concentration+of+cytokines+in+diabetes+and+CVD+%28cardiovascular+disease%29suggests+a+common+inflammatory+state+in+both+diabetes+and+CVD. assertion.
- assertion asSentence The+IL-6-mediated+bFGF+upregulation+is+through+activation+of+JAK%2FSTAT3+and+PI3-Kinase%2FAkt+pathways. assertion.
- assertion asSentence Oncostatin+M+stimulates+proliferation+of+prostate+cacner+22Rv1+cells%2C+in+part+through+activation+of+the+phosphatidylinositol+3-kinase+%28PI+3-K%29+signaling+pathway. assertion.
- assertion asSentence IL6+is+one+of+the+important+factors+in+the+pathogenesis+of+psoriasis. assertion.
- assertion asSentence IL-32+synergizes+with+nucleotide+oligomerization+domain+%28NOD%29+1+and+NOD2+ligands+for+IL-1beta+and+IL-6+production+through+a+caspase+1-dependent+mechanism. assertion.
- assertion asSentence Intracytoplasmic+sperm+injection+patients+with+serum+progesterone+above+0.9+ng%2Fml+have+elevated+serum+and+intrafollicular+concentrations+of+interleukin+6. assertion.
- assertion asSentence IL-6+plays+a+role+in+the+development+and+progression+of+atherosclerosis. assertion.
- assertion asSentence The+impact+of+the+IL6+-634G+allele+on+serum+C-reactive+protein+elevation+is+greater+in+nonsmokers+than+in+current+smokers. assertion.
- assertion asSentence IL-6+production+of+umbilical+cord+vein+endothelial+cells+after+proinflammatory+stimulation+is+not+influenced+by+the+single+nucleotide+polymorphism+at+nucleotide+position+-174. assertion.
- assertion asSentence IL-6+predicts+critical+coronary+stenosis+with+high+sensitivity+and+specificity. assertion.
- assertion asSentence Porphyromonas+gingivalis+vesicle+dose-dependently+induced+PGE%282%29+production+and+up-regulated+COX-2%2C+IL-6+and+IL-8+mRNA+expression+in+gingival+epithelial+cells. assertion.
- assertion asSentence Allicin+supplementation+significantly+reduced+plasma+IL-6+level+and+reduced+perceived+muscle+soreness+after+exercise. assertion.
- assertion asSentence Blood+oxygenation+affects+exercise-induced+IL-6+response+in+hypoxemic+chronic+obstructive+pulmonary+disease+patients. assertion.
- assertion asSentence Hypoglycemia+increases+IL-6+levels+in+healthy+individuals. assertion.
- assertion asSentence IL-6+and+IL-1Ra+polymorphisms+can+be+considered+genetic+markers+for+bronchial+asthma+susceptibility+and%2For+severity+among+Egyptian+children. assertion.
- assertion asSentence There+is+an+increase+of+serum+levels+of+IL-6+and+TNF-alpha+in+autoimmune+disease+patients+with+M.+penetrans+infection+than+the+control+groups. assertion.
- assertion asSentence The+population+with+the+IL6+GG%2BCG+genotype+has+a+higher+risk+for+prostate+cancer. assertion.
- assertion asSentence High+serum+interleukin-6+level+is+associated+with+hepatocellular+carcinoma+development+in+patients+with+chronic+hepatitis+B. assertion.
- assertion asSentence Epicatechin+suppresses+the+production+of+pro-inflammatory+cytokines%2C+IL6+and+IL-8. assertion.
- assertion asSentence Variants+in+the+coagulation+factor+2+receptor+%28F2R%29+gene+influence+the+risk+of+myocardial+infarction+in+men+through+an+interaction+with+interleukin+6+serum+levels. assertion.
- assertion asSentence Interleukin-6+is+significantly+associated+with+increased+circulating+levels+of+asymmetric+dimethylarginine+in+patients+with+septic+shock. assertion.
- assertion asSentence Activated+microglial+cell-derived+IL-6+influences+retinal+neurosphere+formation+and+differentiation. assertion.
- assertion asSentence Interleukin-6+is+a+stronger+prognostic+predictor+than+high-sensitive+C-reactive+protein+in+patients+with+chronic+stable+heart+failure. assertion.
- assertion asSentence IL-6+acts+as+an+inducer+of+inflammatory+cytokines+and+enhances+the+inflammatory+response+of+peptidoglycan-stimulated+synovial+fibroblasts+in+rheumatoid+arthritis. assertion.
- assertion asSentence sCD14+and+il-6+levels+are+associated+with+inflammation+and+protein-energy+wasting+in+hemodialysis+patients. assertion.
- assertion asSentence IL-6+leads+to+a+marked+production+of+IL-10+in+multiple+myeloma+cells+and+enhances+their+proliferation+up+to+160%25. assertion.
- assertion asSentence Mechanical+injury+potentiates+the+catabolic+effects+of+TNFalpha+and+IL-6%2FsIL-6R+in+causing+proteoglycan+degradation+in+human+and+bovine+cartilage. assertion.
- assertion asSentence Males+with+IL-6-174GG+genotype+are+prone+to+develop+Crohn+disease+at+a+younger+age+than+males+with+the+IL-6-174G+--%3E+C+genotype. assertion.
- assertion asSentence PKR+plays+an+important+role+in+mediating+the+cytokine+gene+expression+induced+by+LMP1+through+NF-kappaB+activation+and+histone+H3+Ser+10+phosphorylation. assertion.
- assertion asSentence LL-37-stimulated+production+of+IL-6+in+airway+epithelial+cells+via+activation+of+NFkappaB+signaling+pathway. assertion.
- assertion asSentence IL-6%2FIL-10+genetic+polymorphisms+are+correlated+with+a+high+short-term+risk+of+acute+postoperative+cardiovascular+events+in+patients+with+peripheral+artery+disease+receiving+surgical+revascularization+and+with+endothelial+dysfunction+in+these+patients. assertion.
- assertion asSentence The+secreted+level+of+IL-6+and+IL-8+depended+on+the+degree+of+hypoxia+in+HUVEC+cells. assertion.
- assertion asSentence Diagnostic+value+of+interleukin-6+and+C-reactive+protein+on+early+onset+bacterial+infection+in+preterm+neonates+with+respiratory+distress. assertion.
- assertion asSentence In+CFTRDeltaF508+cells%2C+the+extracellular+glutathione+levels+are+decreased%2C+leading+to+a+greater+sensitivity+to+reactive+oxygen+species%2C+providing+an+explanation+for+the+hyperactivation+of+the+p38+and+ERK+MAPKs+and+increased+IL-6+synthesis. assertion.
- assertion asSentence High+serum+IL-6+is+associated+with+cervical+carcinoma. assertion.
- assertion asSentence Leprosy+patients+with+oral+infections+%28OI%29exhibited+decreased+serum+IL-6+levels+when+compared+to+patients+without+OI. assertion.
- assertion asSentence Nrf2+induces+interleukin-6+%28IL-6%29+expression+via+an+antioxidant+response+element+within+the+IL-6+promoter. assertion.
- assertion asSentence IL6+locus+regulates+the+serum+CRP+levels+and+inflammatory+pathways. assertion.
- assertion asSentence Exposing+Caco-2+cells+to+increasing+doses+of+phytic+acid+increased+Il6%2FIl6R+transcript+levels. assertion.
- assertion asSentence The+presence+of+the+A+allele+of+the+PZ+FG79A+polymorphism+has+a+higher+protective+effect+against+recurrent+pregnancy+loss+than+the+presence+of+the+G+allele+of+the+IL6+C634G+polymorphism. assertion.
- assertion asSentence IL6+mRNA+levels+are+significantly+higher+in+peripheral+blood+mononuclear+cells+in+highly+trained+subjects+compared+to+sedentary+subjects. assertion.
- assertion asSentence IL-6+and+IL-6+receptor+interaction+enhances+migration+of+chondrosarcoma+through+an+increase+in+MMP-13+production. assertion.
- assertion asSentence Elevated+levels+of+miR-203+lead+to+increased+secretion+of+MMP-1+and+IL-6+via+the+NF-kappaB+pathway+in+rheumatoid+arthritis+synovial+fibroblasts. assertion.
- assertion asSentence Inhibitory+effects+of+chelidonic+acid+on+IL-6+production+by+blocking+NF-kappaB+and+caspase-1+in+HMC-1+cells. assertion.
- assertion asSentence Change+in+amount+body+fat+and+levels+of+IL-6+contribute+to+insulin+resistance+in+type+1+diabetes+patients+with+and+without+diabetic+nephropathy. assertion.
- assertion asSentence Increase+in+inflammation+mediatiors+Il6%2FC-reactive+protein+is+associated+with+the+loss+of+skeletal+muscle+in+free-living+non-sarcopenic+older+men+and+women. assertion.
- assertion asSentence The+higher+the+serum+IL-6+levels+on+postoperative+day+1%2C+the+higher+the+risk+of+early+postoperative+recurrence%2C+even+when+curative+pulmonary+resection+can+be+accomplished+in+lung+cancer+patients. assertion.
- assertion asSentence The+presence+of+both+MTHFR+rs1801133+T+and+IL-6+rs1800795+C+alleles+increases+the+odds+of+developing+Alzheimer+disease+by+2.5+and+vascular+dementia+by+3.7-fold. assertion.
- assertion asSentence TWEAK+inhibited+IL-6+production+from+total+synovial+cells+from+rheumatoid+arthritis+. assertion.
- assertion asSentence In+mononuclear+cells+carrying+the+TC+genotype+of+rs5743836%2C+IL-6+up-regulates+TLR9+expression. assertion.
- assertion asSentence Ligand-stimulated+EGFR+activated+NFkappaB-dependent+transcription+and+induced+secretion+of+IL-6+and+plasminogen+activator+inhibitor. assertion.
- assertion asSentence TRPV1+induced+increases+in+IL-6%2FIL-8+release+occur+through+TAK1+activation+of+JNK1-dependent+and+JNK1-independent+signaling+pathways. assertion.