Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP27484.RAbRT1IbmWQP7qkDh4WDVtPh3aPiA1r4QUCm0Rn7RJ6EA130_assertion description "[Missense mutations in PTCH may be rare causes of isolated cleft lip and/or palate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27484.RAbRT1IbmWQP7qkDh4WDVtPh3aPiA1r4QUCm0Rn7RJ6EA130_provenance.
- NP27485.RATLxEQRopBQcxVoIu2K9w6bw0h4fgrM4eRG-UcuN5_WU130_assertion description "[This variant was absent in the NBCCS patient that did not develop basal cell carcinomas, suggesting that this variant could have favored the development of skin cancers, in patients carrying the PTCH1 mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27485.RATLxEQRopBQcxVoIu2K9w6bw0h4fgrM4eRG-UcuN5_WU130_provenance.
- NP27486.RAYtGeDXLtw2aTgiG4D41xLpyqzLcXYis66hWbwN98sDc130_assertion description "[Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27486.RAYtGeDXLtw2aTgiG4D41xLpyqzLcXYis66hWbwN98sDc130_provenance.
- NP27491.RAcsPLDRfGlJ66wVfy4ezTzsIgi5F4giSCbGvsi8Rw3XM130_assertion description "[In summary, our results indicate that both PTCH and SMOH represent important targets for genetic alterations in sporadic BCCs and PNETs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27491.RAcsPLDRfGlJ66wVfy4ezTzsIgi5F4giSCbGvsi8Rw3XM130_provenance.
- NP27492.RAYSiiAcbkZ2YQaFncs2Th2iKx6G9gaRP-nOViAn67_HQ130_assertion description "[The expression pattern of PDX-1, SHH, Patched and Gli-1 is associated with pathological and clinical features in human pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27492.RAYSiiAcbkZ2YQaFncs2Th2iKx6G9gaRP-nOViAn67_HQ130_provenance.
- NP27493.RAS4CBaEOx7CLUU_VoSOPDd90YXJ2EZa48tkq9dCQlh3c130_assertion description "[Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27493.RAS4CBaEOx7CLUU_VoSOPDd90YXJ2EZa48tkq9dCQlh3c130_provenance.
- NP27497.RAUdJOoiBy1YgEPVThx0Pme-bKmb1mAajYf2ATOB5bMFQ130_assertion description "[]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27497.RAUdJOoiBy1YgEPVThx0Pme-bKmb1mAajYf2ATOB5bMFQ130_provenance.
- NP27499.RAXQnWKSJ8VlGZRyB3V46dEu-TG_2FhxdXIxzu3tJ9E-I130_assertion description "[Structural variation of chromosomes in autism spectrum disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27499.RAXQnWKSJ8VlGZRyB3V46dEu-TG_2FhxdXIxzu3tJ9E-I130_provenance.
- NP27501.RAcyLEeKYEDmk5ZQV8t5PTTPIEawkHuycg2zwLKkU6ZQk130_assertion description "[Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27501.RAcyLEeKYEDmk5ZQV8t5PTTPIEawkHuycg2zwLKkU6ZQk130_provenance.
- NP27502.RAQeF-0F3v1oxlfk6EsFHkj3-4E97JfXLasiz-t6pa-48130_assertion description "[Deletion in Xp22.11: PTCHD1 is a candidate gene for X-linked intellectual disability with or without autism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27502.RAQeF-0F3v1oxlfk6EsFHkj3-4E97JfXLasiz-t6pa-48130_provenance.
- NP27503.RASyqmlLchbKVer6jWugwgg2hyZElUKZMZeQ-rxDYj7hw130_assertion description "[]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27503.RASyqmlLchbKVer6jWugwgg2hyZElUKZMZeQ-rxDYj7hw130_provenance.
- NP27508.RAYpi3mG88jNkFrw9a0d-qGZvF3b6lNVOavNIFNzWkey8130_assertion description "[PTEN down-regulates IL-17 expression in a murine model of toluene diisocyanate-induced airway disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27508.RAYpi3mG88jNkFrw9a0d-qGZvF3b6lNVOavNIFNzWkey8130_provenance.
- NP27509.RAe9sdfTrPD3tPmHbWgKuEfG9NpS-s2GkXCLCO4Py0qe8130_assertion description "[We review the scanty literature data on the association of Cowden syndrome and autism and emphasize that the association of progressive macrocephaly and pervasive developmental disorder seems to be an indication for screening for PTEN mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27509.RAe9sdfTrPD3tPmHbWgKuEfG9NpS-s2GkXCLCO4Py0qe8130_provenance.
- NP27520.RASRpUgH5HEQtCD9fewT3_g5IBurupS20RK5tYKLYV2JE130_assertion description "[We suggest that PTEN gene testing be considered for patients with autistic behaviour and extreme macrocephaly.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27520.RASRpUgH5HEQtCD9fewT3_g5IBurupS20RK5tYKLYV2JE130_provenance.
- NP27524.RAdmLNvBhT1UrhAHDw9XjEUtGuMuS_-XgPNDVDNKl8Tw0130_assertion description "[The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27524.RAdmLNvBhT1UrhAHDw9XjEUtGuMuS_-XgPNDVDNKl8Tw0130_provenance.
- NP27525.RATfnE4tOw-424dfHCXEP_bF4PNS6-qvQ8X4wa9st1CVQ130_assertion description "[In adults, PTEN mutations cause Cowden syndrome where, in addition to the macrocephaly, there is a higher risk of tumour development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27525.RATfnE4tOw-424dfHCXEP_bF4PNS6-qvQ8X4wa9st1CVQ130_provenance.
- NP27528.RARJFi3zRY8_HYsBZG6v_SVzVS29KAWVfBxySsh9N2MGo130_assertion description "[The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27528.RARJFi3zRY8_HYsBZG6v_SVzVS29KAWVfBxySsh9N2MGo130_provenance.
- NP27533.RATIKkE0k4YLiNsCiWZjPnokCBMB205e7RYRa_3XJDKG4130_assertion description "[Neonatal estrogenic exposure suppresses PTEN-related endometrial carcinogenesis in recombinant mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27533.RATIKkE0k4YLiNsCiWZjPnokCBMB205e7RYRa_3XJDKG4130_provenance.
- NP27535.RAfl7XbdVR5A_BYqoyZSeDqsFnyUgKaSutUJPcnhly1W4130_assertion description "[PTEN1 is frequently mutated in primary endometrial carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27535.RAfl7XbdVR5A_BYqoyZSeDqsFnyUgKaSutUJPcnhly1W4130_provenance.
- NP27537.RAXuYp0iofPNkAecqQnaFYoS-jrpMAc2iYvb5i43dCG_M130_assertion description "[Sequencing analysis confirmed the presence of PTEN splice-acceptor site mutation in intron 8 (c.1027-2A>G), a germline mutation which had not been previously reported in CS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27537.RAXuYp0iofPNkAecqQnaFYoS-jrpMAc2iYvb5i43dCG_M130_provenance.
- NP27541.RAVAAoytpmQW0YmEZzXVApb6Yf17amWwsG5eaqHNkdc9o130_assertion description "[A novel germline mutation of the PTEN gene in a patient with macrocephaly, ventricular dilatation, and features of VATER association.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27541.RAVAAoytpmQW0YmEZzXVApb6Yf17amWwsG5eaqHNkdc9o130_provenance.
- NP27548.RAcW-GtyIcwpzdyH-tqZusKY1U844G6S2W4uD1BPVWJXs130_assertion description "[The intensity of PTEN-positive immunohistochemical production in aorta of the hypertension group was weaker than that of the hypertension and captopril group, and likewise, it was weaker than the control.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27548.RAcW-GtyIcwpzdyH-tqZusKY1U844G6S2W4uD1BPVWJXs130_provenance.
- NP27551.RAQDX4_2TOsAVU2N5jbMI5yMv_SWU98Givt3yi7CNo4Oc130_assertion description "[PTEN mutation in a family with Cowden syndrome and autism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27551.RAQDX4_2TOsAVU2N5jbMI5yMv_SWU98Givt3yi7CNo4Oc130_provenance.
- NP27560.RATzXkB7_DDAjSKz9suvTr2qTHlez2y0fr_NzO7lyelHM130_assertion description "[This region includes the PTEN gene, mutations of which have been reported to cause Cowden disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27560.RATzXkB7_DDAjSKz9suvTr2qTHlez2y0fr_NzO7lyelHM130_provenance.
- NP27563.RAcHW8c6BGbbm81THGIC7erGVqOgrDxDNt1P9-XyLPbhE130_assertion description "[Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27563.RAcHW8c6BGbbm81THGIC7erGVqOgrDxDNt1P9-XyLPbhE130_provenance.
- NP27564.RAd_yFqn55MUV_BRdk2C0icULJCAjhkYy2bRNcFnyGzTw130_assertion description "[Quantitative MRI establishes the efficacy of PI3K inhibitor (GDC-0941) multi-treatments in PTEN-deficient mice lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27564.RAd_yFqn55MUV_BRdk2C0icULJCAjhkYy2bRNcFnyGzTw130_provenance.
- NP27568.RAadUXjUGGX6db2tvmoeNZ_2VaXbhDeA56xeRux9uOJC4130_assertion description "[These data support the notion that PTEN alterations occur in some metastatic melanomas, and that mutation of this gene plays a role in the progression of some forms of melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27568.RAadUXjUGGX6db2tvmoeNZ_2VaXbhDeA56xeRux9uOJC4130_provenance.
- NP27572.RAQ3aCpGZWf2gWHA0TujXLQ7bEADdLSXVoBXdB7r39nhM130_assertion description "[]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27572.RAQ3aCpGZWf2gWHA0TujXLQ7bEADdLSXVoBXdB7r39nhM130_provenance.
- NP27581.RAcSbKzktdqnau73z3pnxP3ocsrietPZIoZTcMZPMt1Yw130_assertion description "[Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27581.RAcSbKzktdqnau73z3pnxP3ocsrietPZIoZTcMZPMt1Yw130_provenance.
- NP27582.RARYbAudd8ZBVWUexL-kNDKKkd7di715im0Zkw_ryJhoU130_assertion description "[PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27582.RARYbAudd8ZBVWUexL-kNDKKkd7di715im0Zkw_ryJhoU130_provenance.
- NP27584.RAYpd1yEPicJA_4JcZwPXhb3300rslTrJGrOyCF8GG96c130_assertion description "[The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27584.RAYpd1yEPicJA_4JcZwPXhb3300rslTrJGrOyCF8GG96c130_provenance.
- NP27589.RAZZSNdbKR2zYrhCcF1c6uhFd-54frLLumzjj9BLVK0tI130_assertion description "[Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27589.RAZZSNdbKR2zYrhCcF1c6uhFd-54frLLumzjj9BLVK0tI130_provenance.
- NP27593.RAR4nzi_Orv8nTy4sNNGyU5TwdhOAcqnK3FeR9Ol3rPso130_assertion description "[Germline mutation of the tumour suppressor PTEN in Proteus syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27593.RAR4nzi_Orv8nTy4sNNGyU5TwdhOAcqnK3FeR9Ol3rPso130_provenance.
- NP27599.RAcxwXAE6ekpNP-tITfjU0DPdNYxBZoNhHCp9CsFH42j4130_assertion description "[A novel germline mutation of the PTEN gene in a patient with macrocephaly, ventricular dilatation, and features of VATER association.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27599.RAcxwXAE6ekpNP-tITfjU0DPdNYxBZoNhHCp9CsFH42j4130_provenance.
- NP27600.RAS5ClGnvoUf9d0yn9BL3Sm0XBMaa1QMg8E4yaoVu8pA4130_assertion description "[]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27600.RAS5ClGnvoUf9d0yn9BL3Sm0XBMaa1QMg8E4yaoVu8pA4130_provenance.
- NP27605.RAbanIIsy29DfCdhV--iam5CH68QQh9dvXjAx50rhz2PI130_assertion description "[In this study, a single topical application of either 7,12-dimethylbenz[a]anthracene (DMBA) or benzo[a]pyrene (B[a]P), alone, was found to elicit squamous cell carcinomas (SCCs) in the BK5.EP1 transgenic mice, but not in WT mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27605.RAbanIIsy29DfCdhV--iam5CH68QQh9dvXjAx50rhz2PI130_provenance.
- NP27607.RAT221RxvPGwG4TtrtUlIJH-GRy783qV66fPqGApTjt8U130_assertion description "[Chemopreventive effects of ONO-8711, a selective prostaglandin E receptor EP(1) antagonist, on breast cancer development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27607.RAT221RxvPGwG4TtrtUlIJH-GRy783qV66fPqGApTjt8U130_provenance.
- NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_assertion description "[Results of the present study indicate that 1) PGE(2) promotes survival of human endometriotic cells through EP2 and EP4 receptors by activating ERK1/2, AKT, nuclear factor-kappaB, and beta-catenin signaling pathways; 2) selective inhibition of EP2 and EP4 suppresses these cell survival pathways and augments interactions between proapoptotic proteins (Bax and Bad) and antiapoptotic proteins (Bcl-2/Bcl-XL), facilitates the release of cytochrome c, and thus activates caspase-3/poly (ADP-ribose) polymerase-mediated intrinsic apoptotic pathways; and 3) these PGE(2) signaling components are more abundantly expressed in ectopic endometriosis tissues compared with eutopic endometrial tissues during the menstrual cycle in women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.
- NP27612.RAW3wVFWmqFntmaTcflQnsSfCIv8JVCHCXo7KGD3Jrd3c130_assertion description "[Using mice deficient in 1 of 4 prostaglandin E2 (PGE2) receptors -- specifically, the EP2 receptor -- we show that Ep2(-/-) females are infertile secondary to failure of the released ovum to become fertilized in vivo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27612.RAW3wVFWmqFntmaTcflQnsSfCIv8JVCHCXo7KGD3Jrd3c130_provenance.
- NP27613.RATuW_11J0ayA0mYgiVvigU7Pfbk277uJQi-wD5LGpsvU130_assertion description "[Our findings provide further evidence that polymorphisms in PTGER3 might play a significant role in aspirin hypersensitivity among Korean asthmatics.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27613.RATuW_11J0ayA0mYgiVvigU7Pfbk277uJQi-wD5LGpsvU130_provenance.
- NP27622.RAXHzR59Wc8_1WONuIsq-pt7PDW-Gb6xy5EeR3BToXUr4130_assertion description "[Prostaglandin E2 regulates B cell proliferation through a candidate tumor suppressor, Ptger4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27622.RAXHzR59Wc8_1WONuIsq-pt7PDW-Gb6xy5EeR3BToXUr4130_provenance.
- NP27628.RATiiV3E8pyj29or0mHYolHJh6UoQQ9BWpBmfkxHFaQ-s130_assertion description "[Pharmacology of acebutolol in animals].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27628.RATiiV3E8pyj29or0mHYolHJh6UoQQ9BWpBmfkxHFaQ-s130_provenance.
- NP27629.RAfNs8BQXhBXXtqX3YFgFWa252L4qpUPxTbfREmVW66FM130_assertion description "[Genetic and ethnic risk factors associated with drug hypersensitivity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27629.RAfNs8BQXhBXXtqX3YFgFWa252L4qpUPxTbfREmVW66FM130_provenance.
- NP27634.RAZ-tiF1HZ2w2stXamWhet0BGseKApPoaBL-4iJrUStuA130_assertion description "[We hypothesized that pulmonary overexpression of prostacyclin synthase may prevent the development of murine lung tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27634.RAZ-tiF1HZ2w2stXamWhet0BGseKApPoaBL-4iJrUStuA130_provenance.
- NP27641.RASIumdt61istIlMyYPMwTBo-MQhBqRVU6q_0spzQyt10130_assertion description "[GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27641.RASIumdt61istIlMyYPMwTBo-MQhBqRVU6q_0spzQyt10130_provenance.
- NP27643.RAbEkqDAogTCE8e-_FM3X9GbtQvZxqN3Vu1FLWUrTDnSo130_assertion description "[The results of the study suggest participation of COX-1, COX-2 and iNOS, but not nNOS, in transmission of pain stimuli in STZ-induced diabetic hyperalgesia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27643.RAbEkqDAogTCE8e-_FM3X9GbtQvZxqN3Vu1FLWUrTDnSo130_provenance.
- NP27648.RAWSSjr9KNb_ExLuSpJ58p6upb8Frbl1fk0SdQCTamX0s130_assertion description "[Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27648.RAWSSjr9KNb_ExLuSpJ58p6upb8Frbl1fk0SdQCTamX0s130_provenance.
- NP27649.RAXnPkWXX0woMYkICx27QgzLEz3A_TXtS3AmERlmJm58s130_assertion description "[Role of prostaglandins generated by cyclooxygenase-1 and cyclooxygenase-2 in healing of ischemia-reperfusion-induced gastric lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27649.RAXnPkWXX0woMYkICx27QgzLEz3A_TXtS3AmERlmJm58s130_provenance.
- NP27651.RAUfzG84pgBbKZU9BfmM1Px77YQFeQL1UYo-zm7HgmEP4130_assertion description "[Role of prostaglandins generated by cyclooxygenase-1 and cyclooxygenase-2 in healing of ischemia-reperfusion-induced gastric lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27651.RAUfzG84pgBbKZU9BfmM1Px77YQFeQL1UYo-zm7HgmEP4130_provenance.
- NP27653.RAZ6HraTlLCXTdXbAt3vVOAC_kFJJQc1EacBmO9OZM2fY130_assertion description "[Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27653.RAZ6HraTlLCXTdXbAt3vVOAC_kFJJQc1EacBmO9OZM2fY130_provenance.
- NP27660.RAXcZOSJkpuYJYg2VmVfALcUQSfn6iohNxGiea99-OWi0130_assertion description "[Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27660.RAXcZOSJkpuYJYg2VmVfALcUQSfn6iohNxGiea99-OWi0130_provenance.
- NP27670.RAVy0iVVVzoQiA3DF6hs8nyUwIsceTSus6cVHIXNLIv7U130_assertion description "[NO-releasing aspirin exerts stronger growth inhibitory effect on Barrett's adenocarcinoma cells than traditional aspirin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27670.RAVy0iVVVzoQiA3DF6hs8nyUwIsceTSus6cVHIXNLIv7U130_provenance.
- NP27677.RATIVhca18dE95LyM7OA8-vgdwaJuuEpBrt1nOZ9vUG68130_assertion description "[Nimesulide prevents oxidative stress damage following transient forebrain ischemia in the rat hippocampus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27677.RATIVhca18dE95LyM7OA8-vgdwaJuuEpBrt1nOZ9vUG68130_provenance.
- NP27679.RAcfF_nzKLM2F94frtaVLvOSSj7CVxmv10dwRNbI6l83A130_assertion description "[Approximately 30-40% of estrogen receptor alpha (ERalpha)-positive breast tumors express high levels of the cyclooxygenase-2 (COX-2) protein, and these high levels have been associated with a poorer prognosis in breast cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27679.RAcfF_nzKLM2F94frtaVLvOSSj7CVxmv10dwRNbI6l83A130_provenance.
- NP27684.RAWWj71vTnBExngFYEieIGaboQ4anxSuz3Frrpy7UkcpA130_assertion description "[Roles of nitric oxide and prostaglandins in pathogenesis of delayed colonic transit after burn injury in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27684.RAWWj71vTnBExngFYEieIGaboQ4anxSuz3Frrpy7UkcpA130_provenance.
- NP27691.RAQ3VWIqldm7MD8Wl9qV9H0Vcxjjh23G0EBoxG-56nvls130_assertion description "[In several neoplastic diseases, including hepatocellular carcinoma, the expression of P-glycoprotein and cyclooxygenase-2 (COX-2) are often increased and involved in drug resistance and poor prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27691.RAQ3VWIqldm7MD8Wl9qV9H0Vcxjjh23G0EBoxG-56nvls130_provenance.
- NP27696.RAdxwAzxCTbrg925_4OHV7OA4-TjCtYiqUluxGqpUSPEk130_assertion description "[Differential effects of selective cyclooxygenase-2 inhibitors in inhibiting proliferation and induction of apoptosis in oral squamous cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27696.RAdxwAzxCTbrg925_4OHV7OA4-TjCtYiqUluxGqpUSPEk130_provenance.
- NP27702.RAYc-3mk02CKUgzgB2PdI4rMtnZ6T6Q5U6MgI8T3oSQXs130_assertion description "[Nuclear factor-kappaB mediates over-expression of cyclooxygenase-2 during activation of RAW 264.7 macrophages in selenium deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27702.RAYc-3mk02CKUgzgB2PdI4rMtnZ6T6Q5U6MgI8T3oSQXs130_provenance.
- NP27709.RAdpaWtQX3AjS7ftoej8EpKdpSQE17ZgA0kjQm4EwnLJE130_assertion description "[Western blots revealed overexpression of -catenin, c-Myc, cyclin D1, inducible nitric oxide synthase and cyclooxygenase-2 in colon tumor samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27709.RAdpaWtQX3AjS7ftoej8EpKdpSQE17ZgA0kjQm4EwnLJE130_provenance.
- NP27710.RAd3FMMHGIh8w4xDixRDQob8Eva2xA3-htqaU3hgKxPoE130_assertion description "[Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27710.RAd3FMMHGIh8w4xDixRDQob8Eva2xA3-htqaU3hgKxPoE130_provenance.
- NP27712.RAReW-T7SCqAArwoZXhndvo8qqCvWFhR8ozaleMThkq4A130_assertion description "[Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27712.RAReW-T7SCqAArwoZXhndvo8qqCvWFhR8ozaleMThkq4A130_provenance.
- NP27714.RAZwTILJKEQze1QJVdlOxuy9wp3yGc0sz_p0Dtpr28a2A130_assertion description "[Aspirin use and survival after diagnosis of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27714.RAZwTILJKEQze1QJVdlOxuy9wp3yGc0sz_p0Dtpr28a2A130_provenance.
- NP27725.RAYYwdTmqwXmjDn2mYl-8GCyO2zxRzLuJE527l1YPAlDI130_assertion description "[These observations suggest a potential role for selective COX-2 inhibitors in the prevention and treatment of esophageal adenocarcinoma for patients with Barrett's esophagus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27725.RAYYwdTmqwXmjDn2mYl-8GCyO2zxRzLuJE527l1YPAlDI130_provenance.
- NP27728.RAbxzGUbRb__OuUakcjJN4Dj1Q_M6AIrwE_qdJutGjgjg130_assertion description "[Examination of COX-2 mRNA expression is useful for predicting the effect of CRT in patients with ESCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27728.RAbxzGUbRb__OuUakcjJN4Dj1Q_M6AIrwE_qdJutGjgjg130_provenance.
- NP27729.RATxNG_PVv7s08A39EK8_Il0kfmW8X14LTxsyLDIsQdqI130_assertion description "[Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27729.RATxNG_PVv7s08A39EK8_Il0kfmW8X14LTxsyLDIsQdqI130_provenance.
- NP27730.RAVu936cBKrR9b68PLyXW3d4gpNQfK-zdUbQmJHbxRe1Q130_assertion description "[COX-2 mRNA expression is a frequent phenomenon in human ESCC tissue samples and plays an important role in the carcinogenesis of ESCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27730.RAVu936cBKrR9b68PLyXW3d4gpNQfK-zdUbQmJHbxRe1Q130_provenance.
- NP27734.RAZeY7vYWlmzOgklnGY6s0rSM-n3GIgbOpsmZ2N43wXNU130_assertion description "[The induction of cyclooxygenase-2 (COX-2) expression is associated with more aggressive gliomas and poor survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27734.RAZeY7vYWlmzOgklnGY6s0rSM-n3GIgbOpsmZ2N43wXNU130_provenance.
- NP27743.RActASNGqXGMnfviZZCjrZTKGBnCpubeoFyq0a4olKMRA130_assertion description "[Early induction of cytokines/cytokine receptors and Cox2, and activation of NF-B in 4-nitroquinoline 1-oxide-induced murine oral cancer model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27743.RActASNGqXGMnfviZZCjrZTKGBnCpubeoFyq0a4olKMRA130_provenance.
- NP27744.RAaQOPDLThpTcLyfemwIvZY09AI2JS50J43MAxiiBJeIU130_assertion description "[The objectives of the present study were, first, to clarify whether androgens are required in the development of hyperinsulinemia, insulin resistance, and hypertension in fructose-fed rats, and second, to determine if cyclooxygenase-1 and cyclooxygenase-2 are also increased in the arteries of these rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27744.RAaQOPDLThpTcLyfemwIvZY09AI2JS50J43MAxiiBJeIU130_provenance.
- NP27749.RAVxB6AKIvLEbK_EVf-ohRTyhSwlwWVc7EnXXzUHMwh9M130_assertion description "[In inflammatory bowel disease, increased production of prostaglandins by cyclooxygenase-2 (COX-2) contributes to bowel dysfunction, inflammatory edema, and hyperemia suggesting that inhibitors of COX-2 may have beneficial effect in gut inflammation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27749.RAVxB6AKIvLEbK_EVf-ohRTyhSwlwWVc7EnXXzUHMwh9M130_provenance.
- NP27750.RAS5hR3An5lTEv0R2q5RDIOK1_oKLWnfT1yrYUYX-3yUA130_assertion description "[While the exact mechanism(s) for this antitumor activity of p-XSC remains to be elucidated, it appears that modulation of beta-catenin expression and COX-2 activity is associated with inhibition of intestinal polyps.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27750.RAS5hR3An5lTEv0R2q5RDIOK1_oKLWnfT1yrYUYX-3yUA130_provenance.
- NP27754.RAQkW-ut3nl77fPrjARs9G-AFlIbPQW0gG_6CXbxKYw_o130_assertion description "[Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27754.RAQkW-ut3nl77fPrjARs9G-AFlIbPQW0gG_6CXbxKYw_o130_provenance.
- NP27755.RAZMFSnRS6VMS0TgLPx2Xoc23ujFm9PBX5XXx4yUeObVY130_assertion description "[In summary, we have showed that levels of COX-2 are increased in both TCC and RCC derived from urinary tract epithelium as well as gastrointestinal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27755.RAZMFSnRS6VMS0TgLPx2Xoc23ujFm9PBX5XXx4yUeObVY130_provenance.
- NP27760.RAUSx4MyeIIOPqMREbggY7fTxa-m6y0lyMYfas7tn_lsU130_assertion description "[Ablation of primary afferent neurons by neonatal capsaicin treatment reduces the susceptibility of the portal hypertensive gastric mucosa to ethanol-induced injury in cirrhotic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27760.RAUSx4MyeIIOPqMREbggY7fTxa-m6y0lyMYfas7tn_lsU130_provenance.
- NP27763.RAc-mgGEWYBpN0AxI36t0Myaqzp8ynQx7c_bZnfb5c8U4130_assertion description "[Apoptosis of murine lupus T cells induced by the selective cyclooxygenase-2 inhibitor celecoxib: molecular mechanisms and therapeutic potential.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27763.RAc-mgGEWYBpN0AxI36t0Myaqzp8ynQx7c_bZnfb5c8U4130_provenance.
- NP27764.RAVIGI0Qv3rk_5RJGVXsNO534htBTpdoxLbe5YEAb25qU130_assertion description "[These findings suggest that increased COX-2 expression and activity, contributes to the pathogenesis of B cell lymphomas and point to a possible role for COX-2 inhibition in their treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27764.RAVIGI0Qv3rk_5RJGVXsNO534htBTpdoxLbe5YEAb25qU130_provenance.
- NP27765.RAf80TtipNfiUAUAeC9DwFMh6ySsftgZUN0Ps9Pv0hWdA130_assertion description "[Epigenetic silencing of novel tumor suppressors in malignant melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27765.RAf80TtipNfiUAUAeC9DwFMh6ySsftgZUN0Ps9Pv0hWdA130_provenance.
- NP27771.RAd5JkcPWCeKtMShASqucFfdgdOZNZU9l73KGEJpuSb78130_assertion description "[COX-2 over-expression can up-regulate the expression of VEGF-C. VEGF-C might promote lymph node metastasis by a lymph-angiogenic pathway, then affect the prognosis of the patients with breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27771.RAd5JkcPWCeKtMShASqucFfdgdOZNZU9l73KGEJpuSb78130_provenance.
- NP27786.RAXpn3dxGU4jQvWYnA8O7iv5b4IviEMQvRuENJqj97Qxw130_assertion description "[As a molecular marker of oxidative stress, increased COX-2 expression was noted in 17 of 18 (94%) TCCs, 4 of 4 (100%) papillomas, and 39 of 47 (83%) PN hyperplasias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27786.RAXpn3dxGU4jQvWYnA8O7iv5b4IviEMQvRuENJqj97Qxw130_provenance.
- NP27793.RAd05rCVz1l-jXwVfUfnNaWG9FYMFShptGwk1iI6Mc-sw130_assertion description "[Distinct roles for basal and induced COX-2 in podocyte injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27793.RAd05rCVz1l-jXwVfUfnNaWG9FYMFShptGwk1iI6Mc-sw130_provenance.
- NP27794.RAeAcTflwZhKXdlLaQNchpY2q6IyH0px5xnUQDmE76COQ130_assertion description "[Manganese induces IGF-1 and cyclooxygenase-2 gene expressions in the basal hypothalamus during prepubertal female development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27794.RAeAcTflwZhKXdlLaQNchpY2q6IyH0px5xnUQDmE76COQ130_provenance.
- NP27797.RAZ-fVA-a8OLAam3JBEV-DhVHai_rxsDcrZDhiflZRbJM130_assertion description "[Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27797.RAZ-fVA-a8OLAam3JBEV-DhVHai_rxsDcrZDhiflZRbJM130_provenance.
- NP27805.RAQgqibHVC4k-nzSm4GOCZWvDi7lbtZhrnoVEvWczMWLg130_assertion description "[The COX-2 inhibitor celecoxib decreased neuronal excitability and prevented epileptogenesis in pilocarpine-induced status epilepticus rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27805.RAQgqibHVC4k-nzSm4GOCZWvDi7lbtZhrnoVEvWczMWLg130_provenance.
- NP27806.RATgvhtxan1cwHLEPZ4NxeOOHAmF7_ScVLA2U2ksqAaFQ130_assertion description "[Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27806.RATgvhtxan1cwHLEPZ4NxeOOHAmF7_ScVLA2U2ksqAaFQ130_provenance.
- NP27807.RASN6KNHskxAJfxcI7foOnmKjsg5X91yogISc9B-MM71Q130_assertion description "[Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27807.RASN6KNHskxAJfxcI7foOnmKjsg5X91yogISc9B-MM71Q130_provenance.
- NP27812.RATKyIxfYBv_KckFqZKYIJx1JjJObbWxK1CU0L_geP5uQ130_assertion description "[Improved antiulcer and anticancer properties of a trans-resveratrol analog in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27812.RATKyIxfYBv_KckFqZKYIJx1JjJObbWxK1CU0L_geP5uQ130_provenance.
- NP27825.RAWekvk-yCEZqMC0do9WNh3Ld_Srgh5OjqxNquREkmLqI130_assertion description "[Mitogenic signal transduction caused by monomethylarsonous acid in human bladder cells: role in arsenic-induced carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27825.RAWekvk-yCEZqMC0do9WNh3Ld_Srgh5OjqxNquREkmLqI130_provenance.
- NP27828.RAfINCbbMecfPexEwWqqP_t0DXlTj5dMrF4_ws6JUN2Rg130_assertion description "[Osteitis fibrosa is mediated by Platelet-Derived Growth Factor-A via a phosphoinositide 3-kinase-dependent signaling pathway in a rat model for chronic hyperparathyroidism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27828.RAfINCbbMecfPexEwWqqP_t0DXlTj5dMrF4_ws6JUN2Rg130_provenance.
- NP27832.RAdw2i7oSJURTn9ljwqzB3Toz2aMnBjSqJmF0sejJ05EE130_assertion description "[Calcitriol-mediated hypercalcaemia and increased interleukins in a patient with sarcoid myopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27832.RAdw2i7oSJURTn9ljwqzB3Toz2aMnBjSqJmF0sejJ05EE130_provenance.
- NP27838.RAcUGM8pI2DvoH4o_mINmyWIeqEpCiARar7M-aAOMbIS4130_assertion description "[Episodes were generally mild, and nearly all cases resolved spontaneously or with discontinuation of calcium and vitamin D. The algorithms used to address hypercalcemia and hypercalciuria in the PaTH trial proved effective in safely resolving clinical episodes of increased urinary or serum calcium and might therefore be helpful to clinicians caring for patients on PTH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27838.RAcUGM8pI2DvoH4o_mINmyWIeqEpCiARar7M-aAOMbIS4130_provenance.
- NP27843.RAbtDUxbzqSuWLqnSANskMWbFCUVdNQtwNsGmV55ge3vU130_assertion description "[Alfacalcidol in the therapy of renal bone disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27843.RAbtDUxbzqSuWLqnSANskMWbFCUVdNQtwNsGmV55ge3vU130_provenance.
- NP27845.RAfHBYeRyaIw1cQNPHIOfErbgwgvvOaAp9yhjzkKCYHwY130_assertion description "[Debilitating muscle cramps after teriparatide therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27845.RAfHBYeRyaIw1cQNPHIOfErbgwgvvOaAp9yhjzkKCYHwY130_provenance.
- NP27847.RAQ7q-P4GXnKnUs2k1J3tTJmOuEHFZ_RiPOSZIXAjkoXU130_assertion description "[Osteoporosis: non-hormonal treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27847.RAQ7q-P4GXnKnUs2k1J3tTJmOuEHFZ_RiPOSZIXAjkoXU130_provenance.
- NP27849.RAXUUb27QtTc6h7CSDHb_ow5IcYMqPZwcgXtHBlyke_kc130_assertion description "[Parathyroid hormone (1-34)-coated microneedle patch system: clinical pharmacokinetics and pharmacodynamics for treatment of osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27849.RAXUUb27QtTc6h7CSDHb_ow5IcYMqPZwcgXtHBlyke_kc130_provenance.
- NP27853.RAQ57XrdTDfoIpSJDlcaLtSUB3t4K8BNqwHsu0noCsqXQ130_assertion description "[]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27853.RAQ57XrdTDfoIpSJDlcaLtSUB3t4K8BNqwHsu0noCsqXQ130_provenance.
- NP27857.RAbgEs-1JPwolMb9xd-QkvWV7njmRf6HQUxu0CA5fwBUE130_assertion description "[]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27857.RAbgEs-1JPwolMb9xd-QkvWV7njmRf6HQUxu0CA5fwBUE130_provenance.
- NP27858.RATyJuc8q18Eg4IlaLJNDwxE6B_nxkSbLlHodb6Yu0JP8130_assertion description "[Prenatal treatment with retinoic acid activates parathyroid hormone-related protein signaling in the nitrofen-induced hypoplastic lung.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27858.RATyJuc8q18Eg4IlaLJNDwxE6B_nxkSbLlHodb6Yu0JP8130_provenance.
- NP27866.RAWfMXUpKSrEQlBrSXAWhrLTUFe67toGEbSV_TfU41q1Q130_assertion description "[Deletion and point mutations of PTHLH cause brachydactyly type E.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27866.RAWfMXUpKSrEQlBrSXAWhrLTUFe67toGEbSV_TfU41q1Q130_provenance.
- NP27867.RAcXf6GdDwq_dhzWud_bprNEm4Rraso2Js9K-NSNtNhdE130_assertion description "[Deletion and point mutations of PTHLH cause brachydactyly type E.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27867.RAcXf6GdDwq_dhzWud_bprNEm4Rraso2Js9K-NSNtNhdE130_provenance.
- NP27868.RAffpzmvzca3RYaGBoZF3ptnL_cVZIM1Zc_u-LcQbD62Q130_assertion description "[Deletion and point mutations of PTHLH cause brachydactyly type E.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27868.RAffpzmvzca3RYaGBoZF3ptnL_cVZIM1Zc_u-LcQbD62Q130_provenance.