Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence When+incubated+with+peroxynitrite%2C+IL-10+has+enhanced+activity+to+inhibit+IL-1+production+of+stimulated+peripheral+blood+mononuclear+leukocytes. assertion.
- assertion asSentence IFN-alpha2b+increases+the+expression+of+this+interleukin+in+primary+activated+human+CD8%2B+T+cells. assertion.
- assertion asSentence IL-10+production+following+whole-blood+stimulation+is+increased+in+first-degree+family+members+of+patients+with+non-paraneoplastic+Lambert-Eaton+myasthenic+syndrome. assertion.
- assertion asSentence IL-10+is+one+of+the+cytokines+up-regulating+the+GM-CSF+expression+in+non-small+cell+lung+cancer. assertion.
- assertion asSentence The+-627C--%3EA+substitution+in+the+IL-10+promoter+represents+a+silent+or+neutral+variant+in+subjects+with+family+history+of+asthma. assertion.
- assertion asSentence IL-6+and+IL-10+polymorphisms+act+synergistically%2C+with+a+fivefold+decreased+risk+of+AD+being+found+in+subjects+who+concomitantly+carry+the+%28-174%29+IL-6+C%2FC+and+the+%28-1%2C082%29+IL-10+A%2FA+genotypes. assertion.
- assertion asSentence Impaired+cell-mediated+response+to+C+trachomatis+is+associated+with+IL-10+genotype+in+subjects+with+high+IL-10+producing+capacity. assertion.
- assertion asSentence IL-10+polymorphisms+are+not+associated+with+celiac+disease+in+the+Spanish+population. assertion.
- assertion asSentence The+carriers+of+the+-592A+allele+in+the+IL-10+promoter+have+higher+risk+of+persistent+HBV+infection. assertion.
- assertion asSentence The+frequences+of+IL-10-1082+G-allele+and+GG+high+expression+genotype+increased+significantly+in+cystic+fibrosis+patients. assertion.
- assertion asSentence Interleukin-10+overexpression+under+control+of+the+constitutive+ubiquitin+C+promoter+ameliorates+acute+rejection+and+preserves+lung+graft+function+for+a+prolonged+time. assertion.
- assertion asSentence Polymorphisms+at+-819+and+-592+sites+in+IL10+promoter+and+their+protein+production+are+associated+with+endometriosis+risk. assertion.
- assertion asSentence Constitutive+expression+of+IL-10+by+lung+inflammatory+cells+is+associated+with+the+risk+for+bronchopulmonary+dysplasia. assertion.
- assertion asSentence Chronic+morphine+treatment+diromg+demdritic+cell+development+from+monocytes+decreased+il-10+secretion. assertion.
- assertion asSentence Il-10+is+produced+by+memory+CD45RA-+CD8%2B+T+cells+during+development+of+infections+with+Leishmania+guyanensis. assertion.
- assertion asSentence Predisposition+to+rheumatic+heart+disease+is+influenced+by+cytokine+gene+polymorphisms+esp.+composite+polymorphism+%28TNF-alpha%28-308+%29A%2FA+and+IL-10%28-1082%29+A%2FA%29+and+%28TNF-alpha%28-308+%29A%2FA+and+IL-10%28-1082%29+G%2FG%29. assertion.
- assertion asSentence Production+of+human+interleukin-10+%28IL-10%29+and+IL-4+partially+contributed+to+HSV-1-induced+KSHV+replication. assertion.
- assertion asSentence Regulatory+function+is+impaired+in+patients+with+multiple+sclerosis. assertion.
- assertion asSentence IL-10+has+a+role+in+the+regulation+of+the+immune+response+in+vivo+by+initiating+actions+that+dampen+inflammation. assertion.
- assertion asSentence Mechanism+of+IgG4+induction+by+regulatory+cells+involves+GITR-GITR-L+interactions%2C+IL-10+and+TGF-beta. assertion.
- assertion asSentence IL-10+suppresses+the+co-stimulatory+effect+of+CD2+in+T+cells+that+have+intact+SHP-1%2C+demonstrating+an+essential+role+of+SHP-1+in+IL-10-mediated+direct+T+cell+suppression. assertion.
- assertion asSentence Plasma+levels+of+IL-10+and+five+single+nucleotide+polymorphisms+in+the+interleukin-10+%28IL-10%29+gene+promoter+in+patients+with+Hodgkin+lymphoma. assertion.
- assertion asSentence Interleukin-10+correlates+with+oxidized+low+density+lipoprotein+in+coronary+culprit+plaques. assertion.
- assertion asSentence Genetic+variation+in+IL10+does+not+affect+outcome+in+unrelated+and+related+hematopoietic+cell+transplantation. assertion.
- assertion asSentence IL-10+single+nucleotide+polymorphisms+are+associated+with+prostate+cancer. assertion.
- assertion asSentence Pan-DR-binding+Hsp60+self+epitopes+induce+an+interleukin-10-mediated+immune+response+in+rheumatoid+arthritis. assertion.
- assertion asSentence IL-10+and+TGF-beta1%2C+as+two+important+immunoregulatory+mediators%2C+participate+in+middle+ear+inflammatory+response%2C+especially+in+chronic+course+of+OME+in+adults. assertion.
- assertion asSentence Marked+antitumor+action+of+lymphokine-activated+lymphocytes+against+malignant+drug-resistant+breast+tumors+is+associated+with+high+expression+level+of+soybean+lectin+receptor+on+the+lymphocytes. assertion.
- assertion asSentence Recombinant+human+IL-10+treatment+suppresses+chemokine+CXCL10+expression+in+human+brain+neurons. assertion.
- assertion asSentence Production+of+IL-10+is+an+important+self-regulatory+function+of+CD4%28%2B%29+T+lymphocytes. assertion.
- assertion asSentence Increased+IL-10+is+associated+with+multiple+myeloma. assertion.
- assertion asSentence IL-6%2FIL-10+genetic+polymorphisms+are+correlated+with+a+high+short-term+risk+of+acute+postoperative+cardiovascular+events+in+patients+with+peripheral+artery+disease+receiving+surgical+revascularization+and+with+endothelial+dysfunction+in+these+patients. assertion.
- assertion asSentence Single+Nucleotide+Polymorphisms+in+IL-10+is+associated+with+metabolic+syndrome+and+type+2+diabetes+mellitus. assertion.
- assertion asSentence IL10+polymorphism+is+not+associated+with+multiple+sclerosis+and+its+subtypes+nor+influences+the+disease+progression. assertion.
- assertion asSentence IL-10+contributes+to+acute+coronary+syndrome+%28ACS%29+pathogenesis. assertion.
- assertion asSentence The+rapid+downregulation+of+FLI-1+expression+after+LPS+stimulation+attenuates+the+induction+of+various+MMPs+and+IL-10+under+inflammatory+conditions. assertion.
- assertion asSentence Missense+mutation+in+IL-10+receptor+that+cause+severe+colitis+in+patients+less+than+12+mo. assertion.
- assertion asSentence The+culture+supernatant+of+mesenchymal+stem+cells+isolated+from+stage+III+breast+cancer+patients+induced+upregulation+of+the+mRNA+expression+levels+of+IL-4%2C+TGF-beta1%2C+IL-10%2C+CCR4+and+CD25+in+peripheral+blood+T+lymphocytes. assertion.
- assertion asSentence The+galectin-1%2FIL-10+functional+axis+is+crucial+in+lung+cancer-mediated+immune+suppression%2C+by+demonstrating+that+galectin-1+can+serve+as+a+target+in+the+development+of+lung+cancer+immunotherapy. assertion.
- assertion asSentence Tumor-derived+cytokines+IL-10+and+IL-6+potentiate+macrophage+colony-stimulating+factor+%28M-CSF%29-inducible+DC-SIGN+expression+along+monocyte-to-macrophage+differentiation. assertion.
- assertion asSentence An+association+of+IL10+promoter+polymorphisms+is+found+with+chronic+recurrent+multifocal+osteomyelitis%2C+demonstrating+an+increased+frequency+of+high+IL-10+expressing+-1082G%2FG+alleles. assertion.
- assertion asSentence Hypermethylation+of+the+IFN-gamma+and+IL-10+genes+is+a+usual+feature+of+the+healthy+and+inflamed+periodontal+tissues. assertion.
- assertion asSentence Functional+gene+polymorphisms+of+interleukin-10+are+associated+with+liver+disease+progression+in+Japanese+patients+with+hepatitis+C+virus+infection. assertion.
- assertion asSentence mTOR+pathway+controls+IL-12%2FIL-10+modulation+by+L.+donovani+in+monocyte-derived+macrophages. assertion.
- assertion asSentence IL-10+modulates+fondaparinux+inhibition+of+monocyte-induced+thrombin+generation. assertion.
- assertion asSentence Decreased+TLR4-mediated+IL-10+production+is+associated+with+increased+risk+of+subsequent+atopic+dermatitis+in+neonates. assertion.
- assertion asSentence CaMKII+upregulates+IL-10+production+by+primary+human+T+lymphocytes+stimulated+through+the+antigen+receptor+or+bypassing+that. assertion.
- assertion asSentence There+is+no+association+of+TNF-alpha+or+IL-10+gene+polymorphisms+with+lepromatous+leprosy+in+Mexican+mestizos+patients+from+northwest+Mexico. assertion.
- assertion asSentence IL-10R1+S138G+loss-of-function+polymorphism+is+associated+with+extrapulmonary+tuberculosis+risk+development+in+Tunisia. assertion.
- assertion asSentence The+haplotype+-185%2F-116+of+IL10+receptor+alpha+in+combination+with+the+haplotype+-754%2F-750+of+IL10+receptor+beta+contributed+towards+mild+malaria. assertion.
- assertion asSentence Role+of+interleukin-11+to+prevent+chemotherapy-induced+thrombocytopenia. assertion.
- assertion asSentence The+up-regulation+of+IL10%2C+IL11+and+IL18+expression+in+tumor-associated+macrophage+by+hypoxia+differed+in+gastric+cancer+cell+lines. assertion.
- assertion asSentence IL-11+administration+exhibits+postconditioning+effects+through+cardiac+STAT3+activation%2C+preventing+myocardial+ischemia-reperfusion+injury. assertion.
- assertion asSentence IL11RA+promoter+polymorphism--rs1061758--may+be+associated+with+the+risk+of+papillary+thyroid+cancer+in+the+Korean+population. assertion.
- assertion asSentence IL-12%28p35%29+transcriptional+repression+in+neonatal+dendritic+cells+takes+place+at+the+chromatin+level. assertion.
- assertion asSentence In+the+subset+of+genes+that+STAT4+programs+for+expression+in+Th1+cells%2C+IL-12-induced+mRNA+levels+remain+increased+for+a+longer+time+than+mRNA+from+genes+that+are+not+programmed. assertion.
- assertion asSentence Hyperglycemia+influenced+IL-12+response+from+peripheral+mononuclear+cells+in+diabetes+mellitus+patients+to+some+degree+during+infection. assertion.
- assertion asSentence IL-12B+3%27untranslated+region+has+no+effect+or+has+a+negligible+effect+on+human+susceptibility+to+tuberculosis. assertion.
- assertion asSentence The+IL12B+1188+%28A--%3EC%29+gene+polymorphism+is+not+involved+in+defining+the+genetic+basis+of+the+susceptibility+to+and+final+outcome+of+peptic+ulcer+disease. assertion.
- assertion asSentence Sequence+variants+in+the+genes+for+the+interleukin-23+receptor+%28IL23R%29+and+its+ligand+%28IL12B%29+confer+protection+against+psoriasis. assertion.
- assertion asSentence Genotypical+variations+of+the+IL-12B+%2840%29+gene+have+not+been+investigated+for+schizophrenic+patients+yet.We+examined+polymorphic+variants+of+IL-12B+%28p40%29. assertion.
- assertion asSentence Single-stranded+RNA+induced+Interleukin-12+production+in+myeloid+dendritic+cells. assertion.
- assertion asSentence C57BL%2F6+mice+transgenic+for+colitis-prone+SJL%2FJ+mouse+p40+variant+synthesize+significantly+more+IL-12p70+upon+lipopolysaccharide+challenge+and+are+more+prone+to+develop+colonic+inflammation+than+are+C57BL%2F6+mice+transgenic+for+the+C57BL%2F6-p40+variant. assertion.
- assertion asSentence Genetic+variation+in+IL12B%2C+a+highly+relevant+candidate+gene%2C+is+a+risk+factor+for+pulmonary+tuberculosis+in+populations+of+African+ancestry. assertion.
- assertion asSentence IL-12Rbeta1-+and+STAT-3--dependent+signals+play+a+key+role+in+the+differentiation+and%2For+expansion+of+human+IL-17-producing+T+cell+populations+in+vivo. assertion.
- assertion asSentence Expression+of+IL-13+mRNA+and+the+FMLP-induced+release+of+IL-13+from+basophils+are+both+inhibited+by+preincubation+of+the+cells+with+synthetic+HIV-1+envelope+gp41+peptides. assertion.
- assertion asSentence IL-13+in+combination+with+TGF-beta+1+increases+production+of+eotaxin-1+in+airway+fibroblasts+from+asthmatic+and+normal+subjects. assertion.
- assertion asSentence IL13+is+associated+with+diabetes+mellitus%2C+type+1+in+Filipinos. assertion.
- assertion asSentence In+transgenic+mice+in+which+IL-13+is+targeted+to+the+lung%2C+IL-13+is+a+potent+stimulator+of+lung+inflammation+and+remodeling+via+IL-11+receptor+alpha-dependent+pathways. assertion.
- assertion asSentence Allele+T+is+associated+with+asthma+and+increases+the+total+plasma+IgE+level+via+enhanced+IL-13+gene+expression. assertion.
- assertion asSentence Gene-gene+interaction+between+GATA3+and+IL13+polymorphisms+can+influence+the+risk+of+childhood+rhinitis. assertion.
- assertion asSentence Molecular+and+structural+basis+of+cytokine+receptor+pleiotropy+in+the+interleukin-4%2F13+system+are+eported. assertion.
- assertion asSentence IL13%2B2044G--%3EA+is+significantly+associated+with+a+reduced+lung+function+in+Korean+children+and+adolescents. assertion.
- assertion asSentence IL13-1512A%3EC+is+a+functional+polymorphism+that+enhances+IL13+expression+by+creating+a+binding+site+for+the+transcription+factor+Oct-1. assertion.
- assertion asSentence GATA-binding+protein+3+%28Gata3%29+is+essentially+required+for+II13+gene+expression+in+super+T%28h%291+cells. assertion.
- assertion asSentence A+polymorphic+variant+of+human+IL-13%2C+R130Q%2Cis+more+active+than+wildtype+IL-13+in+inducing+hydrocortisone-dependent+IgE+synthesis. assertion.
- assertion asSentence Polymorphisms+of+IL-13+is+not+associated+with+Non-Small-Cell+Lung+Carcinoma. assertion.
- assertion asSentence Bronchial+submucosal+mast+cell+IL-13+receptor+alpha+1+expression+is+higher+in+asthmatics+than+normal+controls. assertion.
- assertion asSentence The+D1+domain+of+IL-13Ralpha1+acts+as+an+affinity+converter%2C+through+direct+cytokine+interactions%2C+that+allows+the+shared+receptor+to+respond+differentially+to+IL-4+and+IL-13. assertion.
- assertion asSentence The+IL-13R+A%281%29+%2B1398+A%2FG+polymorphism+does+not+contribute+to+asthma+or+allergic+rhinitis+susceptibility. assertion.
- assertion asSentence Highly+variable+expression+of+IL13Ralpha2+protein+both+within+and+across+specimens+of+glioblastoma+multiforme. assertion.
- assertion asSentence IL-15+is+required+for+expression+of+granulysin-mediated+anticryptococcal+activity+in+CD8+T+cells. assertion.
- assertion asSentence IL-15+alone%2C+similarly+to+IL-18%2C+has+no+significant+ability+for+regulation+of+both+soluble+IL-6+receptors%2C+sIL-6R+and+sgp130%2C+released+by+human+neutrophils. assertion.
- assertion asSentence CD34-CD133-CD7-CD45%28dim%29lin-+hematopoietic+stem+cells+from+human+umbilical+cord+blood+display+an+exquisite+sensitivity+to+IL-15+in+vitro+and+differentiate+into+lymphoid%2Fnatural+killer+cells. assertion.
- assertion asSentence Human+T+cells+constitutively+express+IL-15+that+acts+through+autocrine%2Fjuxtacrine+loops+to+promote+ex+vivo+homeostatic+T+cell+proliferation. assertion.
- assertion asSentence Induces+local+chromatin+modifications+specific+for+the+T-cell+antigen+receptor+variable+gamma-region+gene+segment+and+enhanced+accessibility+conducive+to+subsequent+targeted+gene+rearrangement. assertion.
- assertion asSentence Irradiated+MyD88-deficient+IL-15+transgenic+mice+transferred+with+wild-type+bone+marrow+cells+have+increased+numbers+of+CD8alphaalpha+TCRalphabeta+and+TCRgammadelta+subsets+in+the+intestinal+intraepithelial+lymphocytes. assertion.
- assertion asSentence Respiratory+syncytial+virus+%28RSV%29-induced+up-regulation+of+IL-15+expression+in+THP-1+cells+involves+the+phosphorylation+of+PKC-alpha%2Fbeta. assertion.
- assertion asSentence IL-15+and+IL-15Ralpha+complex+is+10-fold+more+active+than+IL-15+alone+in+stimulating+proliferation+and+survival+of+memory+phenotype+CD8+T+cells. assertion.
- assertion asSentence IL-15+has+dual+roles+in+maintaining+IL-7Ralpha%28low%29CCR7%28-%29+memory+CD8%28%2B%29+T+cells+via+TCR-dependent+and+-independent+mechanisms. assertion.
- assertion asSentence Genetic+treatment+with+pIL-15+and+pIL-21+in+the+presence+or+absence+of+cognate+antigen+can+contribute+to+immune-enhancement+against+HSV. assertion.
- assertion asSentence IL-15+plays+an+important+role+in+dictating+the+composition+rather+than+simply+the+maintenance+of+the+CD8+memory+pool. assertion.
- assertion asSentence Adenovirus+dendritic+cells+and+matured+dendritic+cells+can+efficiently+promote+innate+immune+functions+by+activation+of+NK+cells+through+the+cooperative+activities+of+tmTNF+and+trans-IL-15+mediated+by+cell-to-cell+contact. assertion.
- assertion asSentence IL-15+can+have+innate+anti-tumor+activity+independent+of+natural+killer+cells+and+CD8%28%2B%29+T+cells+and+the+common+gamma%28c%29R. assertion.
- assertion asSentence Monocytes+differentiated+with+GM-CSF+and+IL-15+initiate+Th17+and+Th1+responses+that+are+contact-dependent+and+mediated+by+IL-15. assertion.
- assertion asSentence In+lymphodepleted+cancer+patients%2C+the+serum+IL-15+is+exclusively+present+in+its+heterodimeric+form. assertion.
- assertion asSentence Human+Langerhans+cells+use+an+IL-15R-alpha%2FIL-15%2FpSTAT5-dependent+mechanism+to+break+T-cell+tolerance+against+the+self-differentiation+tumor+antigen+WT1. assertion.
- assertion asSentence IL-16+rs11556218+G%2FT+polymorphism+is+significantly+associated+with+the+risk+of+coronary+artery+disease+in+the+Chinese+Han+population. assertion.
- assertion asSentence Mutations+in+the+5%27+end+of+the+PDZ1+region+of+pro-IL-16+cause+loss+of+its+nuclear+localization+%26+facilitate+CTCL+cell+proliferation+by+decreasing+p27Kip1+expression+thru+increasing+Skp2. assertion.
- assertion asSentence 4-1BB+enhanced+expansion%2C+survival+and+effector+functions+of+newly+primed+CD8%28%2B%29+T+cells. assertion.