Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP346599.RAehgQeRsWHiWoKubhVotFl_n7oCgFOrE5DTCt6Xkb61w130_assertion description "[Cholesteryl ester transfer protein (CETP) deficiency, which has been found only in Japan, is characterized by marked hyperalphalipoproteinemia (HALP) and abnormalities of both low density and high density lipoproteins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346599.RAehgQeRsWHiWoKubhVotFl_n7oCgFOrE5DTCt6Xkb61w130_provenance.
- NP346600.RARl6MVUPjs-nUqem1AOEZe7Qv1kaEe59OrBJEATFLedk130_assertion description "[The human PENUMBRA gene is mapped to chromosome 7q32, a hot spot for deletions in myelodysplastic syndromes and acute myelogenous leukemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346600.RARl6MVUPjs-nUqem1AOEZe7Qv1kaEe59OrBJEATFLedk130_provenance.
- NP346606.RAVS57QZ297Q7UX6TkKRDcMUnHpa9c56AMrVcOKOKdM3s130_assertion description "[Individuals with mutations in SLC6A5 present with hypertonia, an exaggerated startle response to tactile or acoustic stimuli, and life-threatening neonatal apnea episodes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346606.RAVS57QZ297Q7UX6TkKRDcMUnHpa9c56AMrVcOKOKdM3s130_provenance.
- NP346610.RAQv30aKTF-9RD_DZFJvtJ9R8ur-jblFqvbgXzCuELsp0130_assertion description "[The extracellular domain of CLAC-P/collagen type XXV was secreted by furin convertase, and the N-terminus of CLAC deposited in AD brains was pyroglutamate modified.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346610.RAQv30aKTF-9RD_DZFJvtJ9R8ur-jblFqvbgXzCuELsp0130_provenance.
- NP346614.RATLhUf2XtarYt_uMmFdcObVT9UixbNodf0kdooZd8DcQ130_assertion description "[Hence, targeting the non-PRC2 function of EZH2 may have therapeutic efficacy for treating metastatic, hormone-refractory prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346614.RATLhUf2XtarYt_uMmFdcObVT9UixbNodf0kdooZd8DcQ130_provenance.
- NP346619.RAdmJnQrXS41i_TBegeeBVWVMbRthsm3ExPvJmNxH5168130_assertion description "[Proinflammatory cytokines, such as interleukin-1beta (IL-1beta), IL-6, and tumor necrosis factor-alpha (TNF-alpha), are suggested to have an important role in the process of atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346619.RAdmJnQrXS41i_TBegeeBVWVMbRthsm3ExPvJmNxH5168130_provenance.
- NP346620.RAb500wbCfyNr4dJuvDZqrctT82mT14xmmBN1f75_vsQ0130_assertion description "[The results of [3H]thymidine incorporation showed an AT heterozygote-like RDS in fibroblasts from patients with atherosclerosis that appeared to be intermediate between that of AT homozygotes and that of healthy subjects, suggesting a partial deregulation of cell cycle in the patients with atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346620.RAb500wbCfyNr4dJuvDZqrctT82mT14xmmBN1f75_vsQ0130_provenance.
- NP346623.RAY8HXtLmebmJXH39P8UkvaH-e5P5u_rpbSgUUJif31Cs130_assertion description "[The results showed that the PLA2G7, HPGD, EPHX2, and CYP4F8 genes are highly expressed in prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346623.RAY8HXtLmebmJXH39P8UkvaH-e5P5u_rpbSgUUJif31Cs130_provenance.
- NP346630.RAevbDz9aj85mkrNenndOFklYEWZhyTgKliN5l8Y7VxbY130_assertion description "[Microdeletions Glu767(1-bp del), Thr967(1-bp del), and Leu1446(2-bp del) in the human USH2A gene have been reported to cause Usher syndrome type II, a disorder characterized by retinitis pigmentosa (RP) and mild-to-severe hearing loss.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346630.RAevbDz9aj85mkrNenndOFklYEWZhyTgKliN5l8Y7VxbY130_provenance.
- NP346633.RAVgxJ66wXBzn1mqLeFMsTMunwEJAb2rnvjpLrHiNZagg130_assertion description "[Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346633.RAVgxJ66wXBzn1mqLeFMsTMunwEJAb2rnvjpLrHiNZagg130_provenance.
- NP346635.RAbG4NRIkrOBAN-dqPcIM493jmtcvxwdwN0teqzkuzSns130_assertion description "[The CD10(high)AGR2(low) phenotype in primary tumors is predictive of poor outcome; however, the CD10(low)AGR2(high) phenotype is more common in metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346635.RAbG4NRIkrOBAN-dqPcIM493jmtcvxwdwN0teqzkuzSns130_provenance.
- NP346642.RAYZ5v1pmD9hjy_B49ZIXCLyKKorAR9Fnn1QVhI_t2wRc130_assertion description "[Immunohistochemistry confirmed that fibroblasts recruited into pancreatic cancer stroma strongly expressed carbonic anhydrase IX and keratin-8, whose transcripts were upregulated in KM104GFP-5G by oligonucleotide microarray analysis, whereas their expression in fibroblasts within noncancerous pancreatic stroma were under the detection level.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346642.RAYZ5v1pmD9hjy_B49ZIXCLyKKorAR9Fnn1QVhI_t2wRc130_provenance.
- NP346648.RAYM62dT4fQwYsFW8_WNcwOQV5iTV6TAJh9KxUKkAaWMA130_assertion description "[Our data indicate that human c-MET and INK4a/ARF, situated at the nexus of pathways regulating myogenic growth and differentiation, represent critical targets in RMS pathogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346648.RAYM62dT4fQwYsFW8_WNcwOQV5iTV6TAJh9KxUKkAaWMA130_provenance.
- NP346649.RATLRgiVYFyG6R3smp3Yfw8VZ-Vx-ROEZLFm6ex4NJCmw130_assertion description "[Notably, T-SP1 protein was also detectable in prostate cancer and in some ovarian cancer tissues, indicating tumor-related synthesis of T-SP1 beyond testis tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346649.RATLRgiVYFyG6R3smp3Yfw8VZ-Vx-ROEZLFm6ex4NJCmw130_provenance.
- NP346653.RAXC7sm8MAXwwhzHwyFFtruNTYAwKyyZdykSOGDl37yEY130_assertion description "[The HBV genotypes and sequences of the precore/BCP regions were determined in 180 HBV/HCV dually-infected patients and were compared with 90 age, sex and hepatitis B e antigen-matched chronic hepatitis B controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346653.RAXC7sm8MAXwwhzHwyFFtruNTYAwKyyZdykSOGDl37yEY130_provenance.
- NP346655.RAcKxJO0-DUMbfqG3-YwI73zwv9O7mLWWs-2nFUqLCaM8130_assertion description "[The release of [3H]D-aspartate ([3H]D-ASP) or [3H]GABA evoked by glycine and that of [3H]D-ASP or [3H]glycine evoked by GABA from spinal cord synaptosomes were studied in SOD1-G93A(+) mice, a transgenic model of amyotrophic lateral sclerosis, SOD1(+) mice and SOD1(-)/G93A(-) animals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346655.RAcKxJO0-DUMbfqG3-YwI73zwv9O7mLWWs-2nFUqLCaM8130_provenance.
- NP346657.RAazyCSos6mMlbgovFqTaBILJsH0V80NIwd0lJ_OqIQjQ130_assertion description "[We report here that an alphavirus vector, packaged in virus-like replicon particles (VRP) and capable of efficiently infecting DCs, could be repeatedly administered to patients with metastatic cancer expressing the tumor antigen carcinoembryonic antigen (CEA) and that it overcame high titers of neutralizing antibodies and elevated Treg levels to induce clinically relevant CEA-specific T cell and antibody responses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346657.RAazyCSos6mMlbgovFqTaBILJsH0V80NIwd0lJ_OqIQjQ130_provenance.
- NP346666.RAXaZ5-aw-VPTxEkhBHYWX5A83PVzljeUD80u9ruUiX9A130_assertion description "[Decreased IL-13 and IFN-gamma secretion in HIV infection was present in sorted CD4+ and CD8+ T cell subsets, and additional analysis determined concurrent deficiency at the protein and transcriptional level.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346666.RAXaZ5-aw-VPTxEkhBHYWX5A83PVzljeUD80u9ruUiX9A130_provenance.
- NP346674.RASQ8KFlIzwZ3yM2niTkjn5cpKZSAMqkbSIKrhohscb9Y130_assertion description "[In a murine model of arachidonic acid-induced ear inflammation, the LTA(4)H inhibitor, JNJ-26993135 (1-[4-(benzothiazol-2-yloxy)-benzyl]-piperidine-4-carboxylic acid), dose-dependently inhibited ex vivo LTB(4) production in blood, in parallel with dose-dependent inhibition of neutrophil influx (ED(50), 1-3 mg/kg) and ear edema.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346674.RASQ8KFlIzwZ3yM2niTkjn5cpKZSAMqkbSIKrhohscb9Y130_provenance.
- NP346677.RAUrP_Bg2h-Z87XEF_y7V7JxrTn4NbkH6Vp-CYRJ2LF6g130_assertion description "[Here we show that in the chronic helminth infection onchocerciasis (river blindness), where patients have relatively little sign of dermatitis despite the presence of millions of small worms in the skin, T cells can be obtained which bear characteristics of Tr1 cells, producing no IL-2 or IL-4 but substantial amounts of IL-10, variable amounts of IL-5, and some IFN-gamma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346677.RAUrP_Bg2h-Z87XEF_y7V7JxrTn4NbkH6Vp-CYRJ2LF6g130_provenance.
- NP346678.RAVqgm7xjPro8f7e-Dh2xI-bpbWR6CiIyKAG53ttPXccE130_assertion description "[The genes encoding corticotropin releasing hormone receptor 1 (CRHR1), tachykinin receptor 1 (TACR1), gastrin releasing peptide (GRP), and gastrin releasing peptide receptor (GRPR) were selected as candidates for PD based on their biology.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346678.RAVqgm7xjPro8f7e-Dh2xI-bpbWR6CiIyKAG53ttPXccE130_provenance.
- NP346683.RAXhOsnkiPpTSfW3cUgnKk4-_0RNt8Qd26ypRngGhIfIA130_assertion description "[In addition, a significant positive correlation between expression of ULK1 and LC3A (r = 0.401, P < 0.001), and a significant negative correlation between expression of ULK1 and p62 (r = -0.226, P < 0.001) were observed in our breast cancer cohort.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346683.RAXhOsnkiPpTSfW3cUgnKk4-_0RNt8Qd26ypRngGhIfIA130_provenance.
- NP346689.RAbJ3TQ4lpVJIJry2KoV9uqlTE5yQFYUB76ch5vWsHaOQ130_assertion description "[The RNA-binding protein Roquin-1 has been found to be crucial in the maintenance of peripheral tolerance and the prevention of autoimmune disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346689.RAbJ3TQ4lpVJIJry2KoV9uqlTE5yQFYUB76ch5vWsHaOQ130_provenance.
- NP346691.RAb4RHfC4ajOIKmykWtnMa-9SF7dFJwEGmLRISyzJKCqM130_assertion description "[The DLC-1 gene encoding a regulator of the Rho family of small GTPases is altered in breast, prostate, colon, and liver cancer and has several characteristics of a tumor suppressor gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346691.RAb4RHfC4ajOIKmykWtnMa-9SF7dFJwEGmLRISyzJKCqM130_provenance.
- NP346692.RAVXh-qXeu-hW3nNzxSclQxuT7hrykBrUdg7HrlIV86pw130_assertion description "[We have compared high resolution typing of major histocompatibility complex class II loci (HLA-DRB1, DQB1) in 21 patients with BP, 17 with ocular cicatricial pemphigoid (OCP), and 22 with oral pemphigoid (OP) to a panel of 218 haplotypes of normal individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346692.RAVXh-qXeu-hW3nNzxSclQxuT7hrykBrUdg7HrlIV86pw130_provenance.
- NP346694.RAc4BVAerplTCIg5NRsf2dJjwHO2XRkNsXWdOHrBz924c130_assertion description "[Mutations in ASPM do not seem to affect later stages of cortical development, such as neuronal migration, and this might be responsible for the low epileptogenicity of this malformation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346694.RAc4BVAerplTCIg5NRsf2dJjwHO2XRkNsXWdOHrBz924c130_provenance.
- NP346699.RAV3YhWUj7SomNHHkX2Gz6bSRmD8MVH1kDEJwzBz5h8CM130_assertion description "[MMP-9 genotype (C-1562T promoter polymorphism) was determined in 84 patients (73 male) with angiographically defined coronary artery disease (CAD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346699.RAV3YhWUj7SomNHHkX2Gz6bSRmD8MVH1kDEJwzBz5h8CM130_provenance.
- NP346706.RARdLMGcA8sXAImu6TCl6aa8dIjDyon6J6qZXN_Yik4Xg130_assertion description "[Chemoradiotherapy and gefitinib in stage III non-small cell lung cancer with epidermal growth factor receptor and KRAS mutation analysis: cancer and leukemia group B (CALEB) 30106, a CALGB-stratified phase II trial.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346706.RARdLMGcA8sXAImu6TCl6aa8dIjDyon6J6qZXN_Yik4Xg130_provenance.
- NP346707.RAWf3qBsjKuuToI2nqSNwbCy-mw-KktSquWoCbEPfCsQg130_assertion description "[In this replication study, we examined the six top-most associated variants in APOL1 and MYH9 in an independent cohort of African Americans with various nephropathies (44 with FSGS, 21 with HIVAN, 32 with IgA nephropathy, and 74 healthy controls).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346707.RAWf3qBsjKuuToI2nqSNwbCy-mw-KktSquWoCbEPfCsQg130_provenance.
- NP346710.RATDvU70Hso75VgWiMS8LqH3RHq0yDuFKW3CM9sJMkexk130_assertion description "[We report a cooperative study from the French Sarcoma Group and the Mesopath Group on 40 t(X;18)(SYT-SSX)-positive primary intrathoracic SS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346710.RATDvU70Hso75VgWiMS8LqH3RHq0yDuFKW3CM9sJMkexk130_provenance.
- NP346712.RAapGA_6qVUPYg-rnG_28OcU0BvUJT5gnPkGQRTF5zuyI130_assertion description "[Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human colorectal carcinoma tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346712.RAapGA_6qVUPYg-rnG_28OcU0BvUJT5gnPkGQRTF5zuyI130_provenance.
- NP346713.RAYCrijcasX3s_G53WFr5GDGUZsamF9rYd2FS4ZamdVzM130_assertion description "[Slight association between type 1 diabetes and `ff` VDR FokI genotype in patients from the Italian Lazio Region. Lack of association with diabetes complications.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346713.RAYCrijcasX3s_G53WFr5GDGUZsamF9rYd2FS4ZamdVzM130_provenance.
- NP346733.RAccPyzwfWBBGgJSbMAYMMfO-kyu4cugVfVm-tTBXH_us130_assertion description "[We previously reported genetic association of a SNP in the promoter of S100B, rs3788266, with a psychotic form of BPAD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346733.RAccPyzwfWBBGgJSbMAYMMfO-kyu4cugVfVm-tTBXH_us130_provenance.
- NP346740.RAdxzmp_S-D8h7OaD9HAXBbUD3OuZgsFHeZTcP_bL0xtk130_assertion description "[GBM distribution of col IV alpha1-, alpha3-, and alpha5-chain was investigated by immunohistochemistry in 32 patients (21 males and 11 females, mean age at biopsy of 11.5 years) with ultrastructural findings suggestive of AS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346740.RAdxzmp_S-D8h7OaD9HAXBbUD3OuZgsFHeZTcP_bL0xtk130_provenance.
- NP346743.RAYxpfyIk976CgMmn5tp50n8H9R2Eek7NMI4FzzGpo6Yc130_assertion description "[Subsequently, the effect of Aza was investigated in aneurysm formation in the angiotensin II aneurysm mouse model in apolipoprotein E-deficient mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346743.RAYxpfyIk976CgMmn5tp50n8H9R2Eek7NMI4FzzGpo6Yc130_provenance.
- NP346744.RAfABmbCj0jEDrrTWye51LSfSNLh5Jijfziu2019lmwOw130_assertion description "[The CASK gene harbored in a deletion detected by array-CGH as a potential candidate for a gene causative of X-linked dominant mental retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346744.RAfABmbCj0jEDrrTWye51LSfSNLh5Jijfziu2019lmwOw130_provenance.
- NP346749.RAaYe-0SN6jahao02PWNWW7kw1Fggb5ye_u6XXXREem8Y130_assertion description "[Mutations in the glucose-6-phosphate transporter (G6PT) gene in patients with glycogen storage diseases type 1b and 1c.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346749.RAaYe-0SN6jahao02PWNWW7kw1Fggb5ye_u6XXXREem8Y130_provenance.
- NP346750.RAXiGfQUMyEAgqx2jfZpOK0jwiiVEP4SnUTu0hETkFHFo130_assertion description "[Parkin functions as an E3 ubiquitin ligase, and loss of this ubiquitin ligase activity appears to be the mechanism underlying pathogenesis of AR-JP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346750.RAXiGfQUMyEAgqx2jfZpOK0jwiiVEP4SnUTu0hETkFHFo130_provenance.
- NP346755.RAa5Zoc3eFVz4dMalkfSOv0z3csUPM5xNyWCAleKaq6do130_assertion description "[Macrophage inflammatory protein-1-alpha (MIP) was measured from GM-CSF-stimulated cells and GM-CSF was measured from LPS-stimulated cells by ELISA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346755.RAa5Zoc3eFVz4dMalkfSOv0z3csUPM5xNyWCAleKaq6do130_provenance.
- NP346756.RAZc2kCG1lOOCOcMiDjHUSrirV5A5KFYWPL9W_9W6zcwo130_assertion description "[The analysis of previously reported PARK14 patients revealed that those who carried a truncated mutation tended to have a complicated phenotype and atrophies of cortex and cerebellum.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346756.RAZc2kCG1lOOCOcMiDjHUSrirV5A5KFYWPL9W_9W6zcwo130_provenance.
- NP346758.RAdJVH2XftIz0AUko2hnp5Mc7LLPspV3JNS01WtUchERM130_assertion description "[We have previously demonstrated the metastasis-promoting effect of an estrogen receptor beta (ERβ) agonist (genistein) in a patient-derived PCa xenograft model mimicking localized and metastatic disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346758.RAdJVH2XftIz0AUko2hnp5Mc7LLPspV3JNS01WtUchERM130_provenance.
- NP346763.RAbwov-RMogju43iutcGIdej2vRTAuSPMlt8af28Dqw6Q130_assertion description "[A novel aspartic protease gene, ALP56, is up-regulated in human breast cancer independently from the cathepsin D gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346763.RAbwov-RMogju43iutcGIdej2vRTAuSPMlt8af28Dqw6Q130_provenance.
- NP346764.RATIaHzsjvUUYptHc1ij7Cj-TLBPk1ycpQU0hf9X7TLZI130_assertion description "[A polymorphic signal was detected in preimplantation genetic diagnosis (PGD) for aneuploidy, in a patient with repeated early miscarriages.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346764.RATIaHzsjvUUYptHc1ij7Cj-TLBPk1ycpQU0hf9X7TLZI130_provenance.
- NP346777.RAZowX42xQ_uY_fgOoBG6oXEwS6GgrWzk5zH6TaNfYKmw130_assertion description "[The present study provides, to our knowledge, the first experimental evidence for a contribution of ADAMTS-12 as a key mediator in airways disease, interfering with immunological processes leading to inflammation and airway hyperresponsiveness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346777.RAZowX42xQ_uY_fgOoBG6oXEwS6GgrWzk5zH6TaNfYKmw130_provenance.
- NP346787.RAUhbCDfq0-Wkv4M94-9JwhpRMSdIDTSqFz10QGJEoZWo130_assertion description "[Nonsmoker subjects with periodontitis had statistically significantly higher MMP-1, lower MMP-9 and TIMP-1 expression and higher MMP-1/TIMP-1 ratio than smokers; and higher MMP-8 expression and MMP-8/TIMP-1 and MMP-1/TIMP-1 ratios than healthy nonsmokers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346787.RAUhbCDfq0-Wkv4M94-9JwhpRMSdIDTSqFz10QGJEoZWo130_provenance.
- NP346789.RAY8p7qlWVJPaBNtJaMtu_4shQWlsu5DEFR9Lul_NkxK8130_assertion description "[Disruption of IRS-1 in mice retards growth, but diabetes does not develop because insulin secretion increases to compensate for the mild resistance to insulin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346789.RAY8p7qlWVJPaBNtJaMtu_4shQWlsu5DEFR9Lul_NkxK8130_provenance.
- NP346791.RASoOuHgt4xlR8nrk7dJZfRxAxQiRSBA38fzbP9ZX1PCE130_assertion description "[We determined the concentrations of copper, the activities of ceruloplasmin and peptidylglycine alpha-amidating monooxygenase (PAM), and the stimulation index of PAM by the in vitro addition of copper in plasma samples obtained from three male patients with occipital horns and a milder Menkes disease phenotype, having severe copper deficiency due to the defect in copper transport.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346791.RASoOuHgt4xlR8nrk7dJZfRxAxQiRSBA38fzbP9ZX1PCE130_provenance.
- NP346796.RAWRimiKFDd1WQqahREm4mGcx7ZI-MNKU_LI1eIIfEsjM130_assertion description "[In this study, we adopted an adenoviral gene delivery system expressing soluble VEGF receptor 1 (sFlt-1) to further study the role of VEGF in CIA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346796.RAWRimiKFDd1WQqahREm4mGcx7ZI-MNKU_LI1eIIfEsjM130_provenance.
- NP346800.RAVcW91dp2a9O5CqpG54GcXOy8cz3I6Y14MwL8xOI7H3o130_assertion description "[Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346800.RAVcW91dp2a9O5CqpG54GcXOy8cz3I6Y14MwL8xOI7H3o130_provenance.
- NP346803.RARn4gzNkvi-pdSH_xftoI5-fIQ962oBQ54CPeBH1AhGg130_assertion description "[We investigated a possible association of gene polymorphisms both in TAP1 and TAP2 in a cohort of clinically classified leprosy patients (n=222) and in ethnically matched controls (n=223).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346803.RARn4gzNkvi-pdSH_xftoI5-fIQ962oBQ54CPeBH1AhGg130_provenance.
- NP346805.RAZcYt8PVLW39M4Tg0oFhqYgZ-v_s25BYPaHtV4ORHSsw130_assertion description "[Finding two patients with WHIM who do not have detectable mutations of CXCR4 but whose cells are hyperresponsive to CXCL12 raises the possibility that there is more than one genetic basis for WHIM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346805.RAZcYt8PVLW39M4Tg0oFhqYgZ-v_s25BYPaHtV4ORHSsw130_provenance.
- NP346806.RAZnvPFWU5id0BJaX2SG38eyfQzoCHTwE7iMKoMC1uFL4130_assertion description "[Pairwise linkage analysis maps the gene for CSNB1 at Xp11.3 and suggests that the CSNB1 locus is distal to another Xp11 marker, TIMP, and proximal to the OTC locus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346806.RAZnvPFWU5id0BJaX2SG38eyfQzoCHTwE7iMKoMC1uFL4130_provenance.
- NP346809.RAROh8RSGxEkq1QK5VSecwN8xes70260wFlWYTLSTj3Qo130_assertion description "[We identified six single-nucleotide polymorphisms, including rs2046210 (ESR1), rs12662670 (ESR1), rs3803662 (TOX3), rs999737 (RAD51L1), rs8170 (19p13.1), and rs8100241 (19p13.1), significantly associated with the risk of triple-negative breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346809.RAROh8RSGxEkq1QK5VSecwN8xes70260wFlWYTLSTj3Qo130_provenance.
- NP346815.RAfu1tKpkPnp1-5GrCAwpbH7gHgeP685Okl6sKFbx0B7U130_assertion description "[Our study identifies NFκB2 as a target for IKKε in antiviral immunity and describes, for the first time, a role for NFκB2 in the regulation of gene expression in response to viral infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346815.RAfu1tKpkPnp1-5GrCAwpbH7gHgeP685Okl6sKFbx0B7U130_provenance.
- NP346821.RAaA1UHmxZ4rZEU9ljaSwert2xQQYKo1iEc_nI77WLM40130_assertion description "[In contrast, DCC was found downregulated in 59% (10/17) of ovarian tumors tested but correlation was not significant when compared to normal or benign specimens.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346821.RAaA1UHmxZ4rZEU9ljaSwert2xQQYKo1iEc_nI77WLM40130_provenance.
- NP346822.RAZ-t03FJoYNp_lqfyKio4iKwVbMB7k4vNohy1kXbTXAw130_assertion description "[In conclusion, overexpression of the EZH2, RING1, and BMI1 genes is common in MDS and indicate poor prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346822.RAZ-t03FJoYNp_lqfyKio4iKwVbMB7k4vNohy1kXbTXAw130_provenance.
- NP346824.RAcEY6IMXAS6rMf-VYnBYXvymJNzL7nXVtQe_C1rX6nfY130_assertion description "[Expression of PML/RAR alpha fusion protein in human HPC/HSC dictates the acute promyelocytic leukemia (APL) phenotype, largely through these previously unreported effects: rapid induction of HPC/HSC differentiation to the promyelocytic stage, followed by maturation arrest, which is abolished by retinoic acid; reprogramming of HPC commitment to preferential granulopoietic differentiation, irrespective of the HGF stimulus (transduction of single sibling HPC formally demonstrated this effect); HPC protection from apoptosis induced by HGF deprivation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346824.RAcEY6IMXAS6rMf-VYnBYXvymJNzL7nXVtQe_C1rX6nfY130_provenance.
- NP346830.RAVe5YRZaSn1lqMd6XDmLuRavfyBxGEMzlymcE8dbEvOQ130_assertion description "[Interferon-inducible p202 in the susceptibility to systemic lupus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346830.RAVe5YRZaSn1lqMd6XDmLuRavfyBxGEMzlymcE8dbEvOQ130_provenance.
- NP346837.RAeXDrsRwC6cOZFmtyw6Opwz0F41V9rKAQb1CY38pWUTM130_assertion description "[Serum and tissue mRNA determination of ANG-1 and ANG-2 levels by ELISA and RTPCR, from 60 (30 EP and 30 MA) patients with failed early pregnancy and 33 IUPs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346837.RAeXDrsRwC6cOZFmtyw6Opwz0F41V9rKAQb1CY38pWUTM130_provenance.
- NP346839.RASNAPMJZAwSPHMa2BT-8FA6_Xg8q3Tq4RhHKfv1zPYmI130_assertion description "[Similarly, breast cancer cell lines with the 'luminal epithelial-like' phenotype did not express or weakly expressed UGT8, in contrast to malignant, 'mesenchymal-like,' cells forming metastases in nude mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346839.RASNAPMJZAwSPHMa2BT-8FA6_Xg8q3Tq4RhHKfv1zPYmI130_provenance.
- NP346840.RAdOJaBgZXhyv74W7WL0aX59kXuFf8cFOByM2wfCuvK7U130_assertion description "[Multifactor analysis of variance in essential hypertension reveals significant (P = 0.001) differences in SLC activity for the presence or absence of Hp 2-1 phenotype and for body weight (P = 0.0003).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346840.RAdOJaBgZXhyv74W7WL0aX59kXuFf8cFOByM2wfCuvK7U130_provenance.
- NP346841.RAcWMnxE_j3zkxHAthua_m2JhjGEjFScsIdlGXNsS8Ujc130_assertion description "[The rest were receiving IFN for hematologic malignancies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346841.RAcWMnxE_j3zkxHAthua_m2JhjGEjFScsIdlGXNsS8Ujc130_provenance.
- NP346842.RAXRmyi9T1MtfPCDOGiXbQbbdHStKXBX8NArsm5BVq0Io130_assertion description "[To clarify the common self-survival mechanism of the residual motor neurons affected by amyotrophic lateral sclerosis (ALS), we examined motor neurons from 40 patients with sporadic ALS (SALS) and 5 patients with superoxide dismutase 1 (SOD1)-mutated familial ALS (FALS) from two different families (frame-shift 126 mutation and A4 V) as well as four different strains of the SOD1-mutated ALS models (H46R/G93A rats and G1H/G1L-G93A mice).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346842.RAXRmyi9T1MtfPCDOGiXbQbbdHStKXBX8NArsm5BVq0Io130_provenance.
- NP346844.RAUy9yv_PRHrdhvBQ_QRAnZCFCvb7S3QXELo5LFX8FeHk130_assertion description "[Fabry disease is a lysosomal storage disorder caused by an α-galactosidase A (α-Gal A) deficiency and resulting in the accumulation of glycosphingolipids, predominantly globotriaosylceramide (Gb3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346844.RAUy9yv_PRHrdhvBQ_QRAnZCFCvb7S3QXELo5LFX8FeHk130_provenance.
- NP346847.RAcPXGnEGgnfLMp8RfrTBH4He4n5FySG1yadZHBDnuoQI130_assertion description "[We studied mutations in MODY1-4 genes, the presence of GAD antibodies, and HLA DQB1 risk genotypes in 66 Swedish women with GDM and a family history of diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346847.RAcPXGnEGgnfLMp8RfrTBH4He4n5FySG1yadZHBDnuoQI130_provenance.
- NP346852.RAcirAzrDNRQ_qd8PAlwNrIuNZOtvdxRsiD05s4b4AxV0130_assertion description "[Our results demonstrated that PDCD10 modulation of ERK signaling was mediated by MST4, and PDCD10 could be a regulatory adaptor necessary for MST4 function, suggesting a link between cerebral cavernous malformation pathogenesis and the ERK-MAPK cascade via PDCD10/MST4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346852.RAcirAzrDNRQ_qd8PAlwNrIuNZOtvdxRsiD05s4b4AxV0130_provenance.
- NP346853.RAQZ_yyAu4O7BNniF4iViPAL2sov_qkSx75bUWrZHLXaQ130_assertion description "[We have previously reported that expression of the Wnt antagonist genes SFRP1 and SFRP5 is frequently silenced by promoter hypermethylation in breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346853.RAQZ_yyAu4O7BNniF4iViPAL2sov_qkSx75bUWrZHLXaQ130_provenance.
- NP346859.RAUuQqaUA1Ap4LUijFHMcB10Qr9xZqvQYdPrk_CqJ8TIg130_assertion description "[Peripheral nerve injury increased Kcna2 antisense RNA expression in injured DRG through activation of myeloid zinc finger protein 1, a transcription factor that binds to the Kcna2 antisense RNA gene promoter.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346859.RAUuQqaUA1Ap4LUijFHMcB10Qr9xZqvQYdPrk_CqJ8TIg130_provenance.
- NP346864.RAX4icgrPwL88xAzrMSWWqW9t85eChv1yyqmioI2HSPgg130_assertion description "[In conclusion, the protective HO1 promoter polymorphism correlates with a lower coronary artery plaque burden, whereas the protective ENOS 894 G/T polymorphism seems to favourably influence changes of coronary artery plaque composition during statin therapy, but has no significant correlation to the magnitude of coronary atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346864.RAX4icgrPwL88xAzrMSWWqW9t85eChv1yyqmioI2HSPgg130_provenance.
- NP346867.RASlPrT8ZbSrIk_aetostjCDTA_Io8F26v35MDUVPDcb0130_assertion description "[Previous studies from this and other laboratories have shown that treatment of pregnant mice with 3-methylcholanthrene (MC) caused lung tumors in the offspring, the incidence of which correlated with fetal inducibility of Cyp1a1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346867.RASlPrT8ZbSrIk_aetostjCDTA_Io8F26v35MDUVPDcb0130_provenance.
- NP346874.RAWEVa0t3oySlAXA4wjx3bZ9Yo-L33DsJYGEzLbsrIzNE130_assertion description "[Elevated nuclear TG2 and CLSp1 formation was demonstrated in NASH patients, as well as increased activation of apoptosis inducing factor (AIF) and release of cytochrome c. In Hc human normal hepatocytes treated with free fatty acids (FFAs), biochemical analyses revealed that ethanol and FFAs provoked fat accumulation, endoplasmic reticulum (ER) stress, increased nuclear factor kappa B (NFκB), and nuclear TG2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346874.RAWEVa0t3oySlAXA4wjx3bZ9Yo-L33DsJYGEzLbsrIzNE130_provenance.
- NP346875.RAbd1yZpujSGP8RtP7STtol6QfH3HFnMIx4eIllGJTIQA130_assertion description "[Our study indicates that the involvement of chromosomal arms 10q and 3p is characteristic of SCAs and that the VHL gene is involved in a subset of sporadic cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346875.RAbd1yZpujSGP8RtP7STtol6QfH3HFnMIx4eIllGJTIQA130_provenance.
- NP346880.RAcofle7uD0fVM8VBOPiE4iQAY9nJpNMqta0WmzVTXznA130_assertion description "[Of the 85 cases, 23 tested positive for more than two thrombophilias, 16 had factor V Leiden, five had the prothrombin gene G20210A polymorphism, 26 had antiphospholipid antibodies, 10 had elevated homocysteine, four had protein C deficiency, and seven had protein S deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346880.RAcofle7uD0fVM8VBOPiE4iQAY9nJpNMqta0WmzVTXznA130_provenance.
- NP346881.RAZ-l-0JDZUaXrufU676gBU2eTpjB9U1I48gFckB7U9yk130_assertion description "[The expression of the carcinogenesis-related protein Indian hedgehog was also investigated in comparison to GATA factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346881.RAZ-l-0JDZUaXrufU676gBU2eTpjB9U1I48gFckB7U9yk130_provenance.
- NP346886.RAWAdTqnLKbhOKwMCY9NqJGIOk98CmYQtlwjpo1dmKads130_assertion description "[SPF that was higher than 15% was positively correlated with tumor size, differentiation and LN metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346886.RAWAdTqnLKbhOKwMCY9NqJGIOk98CmYQtlwjpo1dmKads130_provenance.
- NP346890.RAWDPJCd53xmeR4AuVmBpOHHEIy1QTaxEkwdpnf6JA-1Y130_assertion description "[Pilot studies confirmed that rhIGF-I could reduce glucose and insulin levels in subjects with type A insulin resistance and those with Rabson-Mendenhall syndrome with sustained beneficial effects on HbA1c.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346890.RAWDPJCd53xmeR4AuVmBpOHHEIy1QTaxEkwdpnf6JA-1Y130_provenance.
- NP346892.RAd26TQ4bDdPr8ww6O8c0jz3_c1nIw9MOAez8sRRLA-wA130_assertion description "[In the other mutant allele, there is a missense mutation substituting serine for Asn462-a mutation identified previously in one allele of the insulin receptor gene in a patient with type-A insulin resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346892.RAd26TQ4bDdPr8ww6O8c0jz3_c1nIw9MOAez8sRRLA-wA130_provenance.
- NP346897.RAdaz7hNs1Gp-VspI8P3ETVxua_ZYBeoX3esdZodB8SDY130_assertion description "[CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346897.RAdaz7hNs1Gp-VspI8P3ETVxua_ZYBeoX3esdZodB8SDY130_provenance.
- NP346899.RARUr5BjiM6eJ7FhMqvzS-j8kMXzg7V-mOEhMsoTBxoWA130_assertion description "[In contrast, expression of CD86 was detected on the AML blasts in more than half of the samples tested and, in some cases, the level of expression was equivalent to that of mature monocytes and activated B lymphocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346899.RARUr5BjiM6eJ7FhMqvzS-j8kMXzg7V-mOEhMsoTBxoWA130_provenance.
- NP346904.RAXAkA2rXrtXToJfySdLs0qCHwJ5EzHmZWWPC_MBj7WBc130_assertion description "[The expression of cytokeratin (CK) 10 and CK18 was examined in 21 samples of SCC arising in MCT.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346904.RAXAkA2rXrtXToJfySdLs0qCHwJ5EzHmZWWPC_MBj7WBc130_provenance.
- NP346909.RAccR9QxvxQOCcTgrpyRFqcxNq3QtCMi7T8__5XD-Pn9Y130_assertion description "[NY-ESO-1-specific immune responses were observed for CD4(+) and CD8(+) T cells from peripheral blood lymphocytes in 4 of 8 neuroblastoma patients, as detected by IFN-gamma enzyme-linked immunospot assay after in vitro stimulation either with the NY-ESO-1 recombinant protein or with the HLA-A2-restricted peptide NY-ESO-1(157-167).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346909.RAccR9QxvxQOCcTgrpyRFqcxNq3QtCMi7T8__5XD-Pn9Y130_provenance.
- NP346914.RAQ0Q_0dVgslc17Ww_mpPZF4uTsl1bo8usU2xTSjRBYrc130_assertion description "[The present data indicate that p63 expression is associated with a worse prognosis in patients with Merkel cell carcinoma, and in localised tumours it represents the single independent predictor of clinical evolution.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346914.RAQ0Q_0dVgslc17Ww_mpPZF4uTsl1bo8usU2xTSjRBYrc130_provenance.
- NP346920.RAagBXZs9CcRCOOjFXemzM3YqH_6NrsM5yvS0qPDjH7vA130_assertion description "[Prognostic significance of p21WAF1/CIP1 expression in tongue squamous cell carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346920.RAagBXZs9CcRCOOjFXemzM3YqH_6NrsM5yvS0qPDjH7vA130_provenance.
- NP346921.RAX5cIo0JZ9Gx30q3CMA6hjGnaNf1jYH2_OuFOI8yaRHw130_assertion description "[Inactivation of a floxed Fgfr2 allele with Dermo1-cre resulted in mice with skeletal dwarfism and decreased bone density.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346921.RAX5cIo0JZ9Gx30q3CMA6hjGnaNf1jYH2_OuFOI8yaRHw130_provenance.
- NP346922.RAYoghagbGdJADRt29w_zXhrxYZipxqHlm33St0Vr21y0130_assertion description "[MBL2 gene polymorphisms are correlated with high-risk human papillomavirus infection but not with human papillomavirus-related cervical cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346922.RAYoghagbGdJADRt29w_zXhrxYZipxqHlm33St0Vr21y0130_provenance.
- NP346925.RAbA26U5O6wR_BM4gBGQiDntfoO2kXzHnyIzjRu7qqq9A130_assertion description "[The current results suggested that cohypermethylation of p14 in combination with DCC and/or CADM1 may be an independent prognostic factor for recurrence in patients with stage I ESCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346925.RAbA26U5O6wR_BM4gBGQiDntfoO2kXzHnyIzjRu7qqq9A130_provenance.
- NP346931.RAc1aG637IPE9UdoMRTvRETOfnLKt2i57xawbOnPHOHX8130_assertion description "[Recombinant human IGF-I alone or combined with its binding protein (IGFBP-3) provides an alternative therapy as IGF-I receptor shares structural and functional homology with the insulin receptor and recombinant human insulin-like growth factor I (rhIGF-I) therapy could improve glucose disposal by signalling through the IGF-I receptor, whilst reducing the adverse effects of high insulin concentrations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346931.RAc1aG637IPE9UdoMRTvRETOfnLKt2i57xawbOnPHOHX8130_provenance.
- NP346943.RAazRPByNsJvDweXbMXpLeMciXW1tpBO6w6FshWjU_9uE130_assertion description "[We further examined whether genetic variants at the interleukin-1 (IL-1) locus would predict clinically incident diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346943.RAazRPByNsJvDweXbMXpLeMciXW1tpBO6w6FshWjU_9uE130_provenance.
- NP346944.RAT11Ms71gHmjyZYm0XaY59niqKcRSe0nKbKKtQtFCgVc130_assertion description "[Mutations in the NOTCH3 gene (NOTCH3) are responsible for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an adult-onset hereditary angiopathy leading to ischemic episodes, vascular dementia and other neurologic deficits.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346944.RAT11Ms71gHmjyZYm0XaY59niqKcRSe0nKbKKtQtFCgVc130_provenance.
- NP346946.RATvZvV0TOI-MZkd65rCtTUWX66n6J-CnYIJsFPtWC8TY130_assertion description "[MiRNA expression and DNA methylation changes were also investigated in FACS sorted CD44(high) oral cancer stem cells from primary tumor samples (CSCs), and in oral rinse and saliva from 15 OSCC patients and 7 healthy volunteers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346946.RATvZvV0TOI-MZkd65rCtTUWX66n6J-CnYIJsFPtWC8TY130_provenance.
- NP346947.RAaEwEsodVt0q9q_EtD8UkNS-kxFauhUfUzrMUt7y1TtE130_assertion description "[Among the malignant tumors, the t(12;16)(q13;p11) resulting in the fusion of DDIT3 and FUS genes is the hallmark of myxoid and round cell liposarcoma and is used as a highly specific and sensitive marker of this entity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346947.RAaEwEsodVt0q9q_EtD8UkNS-kxFauhUfUzrMUt7y1TtE130_provenance.
- NP346956.RAQLPOuhx0YaE82OWjWgeD23qEOR3k8wJoe_OwUUXaLBE130_assertion description "[Poly(ADP-ribose) polymerase-1 (PARP-1) is a sensor for DNA strand breaks and some unusual DNA structures and catalyzes poly(ADP-ribosyl)ation of nuclear proteins with NAD(+) serving as substrate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346956.RAQLPOuhx0YaE82OWjWgeD23qEOR3k8wJoe_OwUUXaLBE130_provenance.
- NP346957.RAV1BdO0tYmnrp-YT58hbz8SrLqSjRM6G1pxnR5rpoAJo130_assertion description "[in contrast to the findings from cross-sectionally based studies, the results from this longitudinal study show that Hp 1-1 individuals are at elevated risk for CHD mortality.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346957.RAV1BdO0tYmnrp-YT58hbz8SrLqSjRM6G1pxnR5rpoAJo130_provenance.
- NP346958.RAbqdaJWmSZhEWUa9ikaKZNNKTphuaid8pLBscE3-ooGU130_assertion description "[FBXL2 expression was strongly suppressed, and yet cyclin D2 protein levels were robustly expressed in acute myelogenous leukemia (AML) and acute lymphoblastic leukemia (ALL) patient samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346958.RAbqdaJWmSZhEWUa9ikaKZNNKTphuaid8pLBscE3-ooGU130_provenance.
- NP346961.RARBLDazuFBfJ2OS9GCJRI4VDwPQQqGMUxH1VgtUioqtc130_assertion description "[Our data reveal that RNAi-mediated downregulation of ERK1/2 expression can lead to potent antitumor activity and chemosensitizing effects in human osteosarcoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346961.RARBLDazuFBfJ2OS9GCJRI4VDwPQQqGMUxH1VgtUioqtc130_provenance.
- NP346965.RAQAUSN1hT3kBzVR2xwIUnfb565r7I1lHCc2Fn6lTIbDQ130_assertion description "[Blood samples from 50 biopsy-proven CHC patients, with no prior anti-viral treatment and persistently elevated serum transaminase levels for 6 months, as well as 15 age- and sex-matched healthy subjects were used for determination of the antioxidants: reduced glutathione (GSH), superoxide dismutase (SOD), α tocopherol and ascorbic acid as well as lipid peroxidation (LPO) index (malondialdehyde [MDA]).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346965.RAQAUSN1hT3kBzVR2xwIUnfb565r7I1lHCc2Fn6lTIbDQ130_provenance.
- NP346970.RAVX9cHsZQdz-xI9fL1HfFizp2EmFFM_qD_vIrc_pwp7c130_assertion description "[Recent studies have suggested that mutations in genes encoding several hypothalamo-pituitary (H-P) transcription factors result in hypopituitarism [isolated GH deficiency (IGHD) and combined pituitary hormone deficiency (CPHD)], which may in turn be related to the neuroanatomy revealed by magnetic resonance (MR) imaging.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346970.RAVX9cHsZQdz-xI9fL1HfFizp2EmFFM_qD_vIrc_pwp7c130_provenance.
- NP346975.RATFGFstyJZlcHAVvRE009ILOek_11q8YkbcaSyNIsMgY130_assertion description "[It is considered that BCL2 translocation precedes MYC events in lymphomagenesis of DHL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346975.RATFGFstyJZlcHAVvRE009ILOek_11q8YkbcaSyNIsMgY130_provenance.
- NP346985.RAUiGQ03RHuSZeEIFtZxF8ssN32Q0Kf7CVxEvxBS2MQ3g130_assertion description "[The differences in the prevalence of BRAF(T1796A) mutations between childhood and adult cases of PTC may well reflect inherent differences in the clinical features of these cancers between the two age groups.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346985.RAUiGQ03RHuSZeEIFtZxF8ssN32Q0Kf7CVxEvxBS2MQ3g130_provenance.
- NP346997.RAT51VknNahrnihkhyr7-6ipWKKTDXUseRFd1bIcFR-cc130_assertion description "[All 3 CARD15 mutations increased susceptibility to a variety of CD subphenotypic manifestations, including early-onset CD in individuals with a family history of IBD, and CD complicated by extraintestinal disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP346997.RAT51VknNahrnihkhyr7-6ipWKKTDXUseRFd1bIcFR-cc130_provenance.