Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP370590.RAUMH5l57Lwk21SkbMyPbnrbJd2HnbAencNwkkN-9zzvg130_assertion description "[Myxoid liposarcomas (LPS) are characterized by the t(12; 16)(q13; p11), which leads to the formation of a FUS-CHOP fusion transcript.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370590.RAUMH5l57Lwk21SkbMyPbnrbJd2HnbAencNwkkN-9zzvg130_provenance.
- NP370591.RAZlnNbID3PTB7BYKwsIPrfohoMLEdZaPucmb6SYfsFtA130_assertion description "[Most data on the therapeutic potential of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) as well as resistance to FAS ligand (FASL) in colorectal cancer have come from in vitro studies using cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370591.RAZlnNbID3PTB7BYKwsIPrfohoMLEdZaPucmb6SYfsFtA130_provenance.
- NP370600.RAUbzEQREwASdhFQn2dqXDWqQRbdRZxk5-xwaZUTtNug4130_assertion description "[Unexpectedly, cells expressing open, active Ezrin could form neither primary orthotopic tumors nor lung metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370600.RAUbzEQREwASdhFQn2dqXDWqQRbdRZxk5-xwaZUTtNug4130_provenance.
- NP370601.RAYLO7-IbyRnbc2TOOz1jkIsFRwpAafjTorexgTuHwVmQ130_assertion description "[Expression of synaptic-like microvesicle proteins, e.g., Synaptic vesicle protein 2 (SV2), synaptobrevin, synapsin 1, and amphiphysin was demonstrated in a majority of GISTs by immunohistochemistry, western blotting, and quantitative reversetranscriptase PCR.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370601.RAYLO7-IbyRnbc2TOOz1jkIsFRwpAafjTorexgTuHwVmQ130_provenance.
- NP370604.RAT39wvyg5JZx7c5jDj5_mFiV-eyhgDshM-SLdpX68kkk130_assertion description "[Genes including PAX6, PITX2, FOXC1, MAF, TMEM114, SOX2, OTX2 and BMP4 have been identified in this way to be associated with developmental eye disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370604.RAT39wvyg5JZx7c5jDj5_mFiV-eyhgDshM-SLdpX68kkk130_provenance.
- NP370606.RAaW3_qFtlk0Qli4oUPpZ9vaHkir2j7w8Vd3sUuM1KnXg130_assertion description "[This review, discusses current medical therapeutic options for prostate cancer including traditional treatments using luteinising hormone releasing analogues (LHRH), anti-androgens and estrogen treatments, and the use of novel drugs directed against molecular targets considered important in oncogenesis and metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370606.RAaW3_qFtlk0Qli4oUPpZ9vaHkir2j7w8Vd3sUuM1KnXg130_provenance.
- NP370607.RAXDzvLieRazfa7doylDwLwEI4SrOFJzDybjECqjtNaoo130_assertion description "[Interleukin-22 genetic polymorphisms and risk of colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370607.RAXDzvLieRazfa7doylDwLwEI4SrOFJzDybjECqjtNaoo130_provenance.
- NP370609.RAU6IEpYBAWg0Q1YRaiaOIBPr0R3s_yMEPh3QNT5ViQx0130_assertion description "[Our analysis further reveals that clinical resistance to these drugs may be attenuated by using multitargeted inhibitors that simultaneously inhibit additional PI3K pathway members.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370609.RAU6IEpYBAWg0Q1YRaiaOIBPr0R3s_yMEPh3QNT5ViQx0130_provenance.
- NP370611.RAVGWWvVRV4_gNCLgLHLfJdUHwmXS2WmButhzcAvuRjdY130_assertion description "[We examined Jumonji domain containing 1A expression in 110 hepatocellular carcinoma samples with quantitative real-time polymerase chain reaction and immunohistochemistry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370611.RAVGWWvVRV4_gNCLgLHLfJdUHwmXS2WmButhzcAvuRjdY130_provenance.
- NP370613.RAep6we2tis8Tx17V2qJqeZqz-gT0Qfi68q4faCkHZIIQ130_assertion description "[Recently it has been demonstrated that the heterozygous loss of function in LEMD3 can result in osteopoikilosis, BOS, and melorheostosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370613.RAep6we2tis8Tx17V2qJqeZqz-gT0Qfi68q4faCkHZIIQ130_provenance.
- NP370615.RAR48C5Eg7_7Qp3ZQRdqMmej4xM3bp1U8eBKEaPLqpVLE130_assertion description "[Recent studies have identified mutations that cause lipin-1 or lipin-2 deficiency in humans, leading to acute myoglobinuria in childhood or the inflammatory disorder Majeed syndrome, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370615.RAR48C5Eg7_7Qp3ZQRdqMmej4xM3bp1U8eBKEaPLqpVLE130_provenance.
- NP370619.RAW9ghnD9gA5j2tyFIWVO98X_fupOHH0JE7aT74gH6PCo130_assertion description "[Education regarding these risky conditions in connection with ALDH2 and ADH2 is vitally important in a new strategic approach aimed at preventing esophageal cancer in East Asians.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370619.RAW9ghnD9gA5j2tyFIWVO98X_fupOHH0JE7aT74gH6PCo130_provenance.
- NP370625.RARlCZF1YWe8KkSAfwKKsInWLK5Atz6mOxXX1UfVafkwg130_assertion description "[IL-6 and CRP levels were elevated among those with lifetime depression and, among those with depression only, IL-6 methylation showed an inverse correlation with circulating IL-6 and CRP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370625.RARlCZF1YWe8KkSAfwKKsInWLK5Atz6mOxXX1UfVafkwg130_provenance.
- NP370629.RAaUWVZPWFjKZpibkcixr2OFOcUre4fumP-rZEc2U7P5o130_assertion description "[A defining characteristic of DSRCT is a specific chromosomal translocation, t(11;22)(p13;q12), that fuses EWS with WT1, leading to a production of two isoforms of chimeric transcription factor, EWS/WT1(-KTS) and EWS/WT1(+KTS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370629.RAaUWVZPWFjKZpibkcixr2OFOcUre4fumP-rZEc2U7P5o130_provenance.
- NP370631.RAU9In6AlkXzS9Z9QAHZIYpXa83QmzMgB12yB1JS6QJ2Q130_assertion description "[Therefore, in a patient with acquired erythrocytosis, it is reasonable to begin the diagnostic work-up with JAK2 mutation analysis to distinguish PV from secondary erythrocytosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370631.RAU9In6AlkXzS9Z9QAHZIYpXa83QmzMgB12yB1JS6QJ2Q130_provenance.
- NP370633.RASkJuiRrMutA6pnX7jItUuQV7uTqeD5A52B9OME5Bkc4130_assertion description "[Tumor necrosis factor (TNF) and interleukin 10 (IL10) are promising candidate susceptibility genes for non-Hodgkin lymphoma (NHL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370633.RASkJuiRrMutA6pnX7jItUuQV7uTqeD5A52B9OME5Bkc4130_provenance.
- NP370636.RAU9t3J_XV_QHYURgRO-ueekbBwRtN6OXeuETkjh0uLTU130_assertion description "[A 7 3/4-year-old girl with short stature was found to have a recombinant (X),dup q chromosome resulting from an apparently unique pericentric inversion (X)(p11.2q26) present in her mother and maternal grandmother.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370636.RAU9t3J_XV_QHYURgRO-ueekbBwRtN6OXeuETkjh0uLTU130_provenance.
- NP370640.RAc-OLtC5R1M9AxYsgvHsiitT2sXmDzrAgwTOWwnEPW-o130_assertion description "[We have recently identified a minimally deleted region encompassing parts of two adjacent genes, termed LEU1 and LEU2 (leukemia-associated genes 1 and 2), and several additional transcripts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370640.RAc-OLtC5R1M9AxYsgvHsiitT2sXmDzrAgwTOWwnEPW-o130_provenance.
- NP370647.RAYzIJ7YSIzTRlnRDO3-teuNbFGlYtBf4V7LXqFcdIBV4130_assertion description "[We conclude that (1) the frequent mutation of p53 and Ha-ras may play a key part in the formation of at least some psoralen + ultraviolet A keratoses; (2) environmental and/or therapeutic ultraviolet exposure may be a major cause of psoralen + ultraviolet A keratosis as most Ha-ras and p53 mutations are induced by ultraviolet light; and (3) psoralen + ultraviolet A itself plays a smaller, though direct, role in causing these mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370647.RAYzIJ7YSIzTRlnRDO3-teuNbFGlYtBf4V7LXqFcdIBV4130_provenance.
- NP370648.RAc-QslHHgWSAPhmtJ3G7vlKr5SWnQnS0Cz2yLsSwO5gE130_assertion description "[The role of LGP2 in virus infection is controversial, and the only LGP2 experiments previously carried out with mammalian influenza A viruses employed an attenuated, mouse-adapted H1N1 A/PR/8/34 (PR8) virus that does not encode the NS1 protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370648.RAc-QslHHgWSAPhmtJ3G7vlKr5SWnQnS0Cz2yLsSwO5gE130_provenance.
- NP370660.RAa6iENE00444UyniI6arf_rPzQwnKMbn7d7-H_b59vZw130_assertion description "[Neuroblastomas frequently show expression of the epidermal growth factor receptor (EGFR) and may therefore be susceptible to EGFR-targeted therapies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370660.RAa6iENE00444UyniI6arf_rPzQwnKMbn7d7-H_b59vZw130_provenance.
- NP370672.RAXdWK5_JhKSNd6peyJrf7uPcHhDXm7C998yrwt91M3W4130_assertion description "[The ablepharon-macrostomia (AMS) and Barber-Say syndromes (BSS) are rare disorders characterized by absence of the eyelids or ectropion, macrostomia, ambiguous genitalia, abnormal ears, rudimentary nipples, and dry, redundant skin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370672.RAXdWK5_JhKSNd6peyJrf7uPcHhDXm7C998yrwt91M3W4130_provenance.
- NP370683.RAY-tBumPBatVaLfCSaA614IIxxdCfZd8NHJNZQ0_Aam4130_assertion description "[Using a cervicovaginal tissue culture system, we found that expression of HD5 and HD6 was induced in response to Neisseria gonorrhoeae (GC, for gonococcus) infection and that conditioned medium from GC-exposed cervicovaginal epithelial cells with elevated levels of HD5 also enhanced HIV infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370683.RAY-tBumPBatVaLfCSaA614IIxxdCfZd8NHJNZQ0_Aam4130_provenance.
- NP370684.RAdocb_xeGn1HS9CI8osA9RT-Aj1iREmPOsItsZd8qwqY130_assertion description "[Hepatoerythropoietic porphyria is caused by a marked deficiency in the activity of uroporphyrinogen decarboxylase, an enzyme that is essential for heme biosynthesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370684.RAdocb_xeGn1HS9CI8osA9RT-Aj1iREmPOsItsZd8qwqY130_provenance.
- NP370688.RAU3K-DJ8uZO5f6Yd3H8lTSgavRnjzlIjxx5kAdtyBZVM130_assertion description "[Rare cases of CML are due to a p190-type of BCR-ABL gene and, in these, the disease tends to have a prominent monocytic component, resembling CMML.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370688.RAU3K-DJ8uZO5f6Yd3H8lTSgavRnjzlIjxx5kAdtyBZVM130_provenance.
- NP370689.RAbjEbwJldpzlEgUe7-Lp3WNk5YfmDzUAj8SzUQtvC-_g130_assertion description "[Catalytic activity of PKC and protein and messenger RNA levels of various PKC isozymes, such as PKC alpha, beta, and gamma, were determined in the prefrontal cortex and hippocampus of both groups.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370689.RAbjEbwJldpzlEgUe7-Lp3WNk5YfmDzUAj8SzUQtvC-_g130_provenance.
- NP370694.RAb_AbJAKCMPViga5OgO7g6SMcKf86bHcd8XV_906E5-E130_assertion description "[The demonstration of a mutation in the SLC34A2 gene helps to confirm the diagnosis of PAM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370694.RAb_AbJAKCMPViga5OgO7g6SMcKf86bHcd8XV_906E5-E130_provenance.
- NP370696.RAYKuaS-OM83DlIRDJE1xx3L2_uBkawmlmRKB_xmrJjNg130_assertion description "[Infection of HHV-8+ primary effusion lymphoma cells with a recombinant Epstein-Barr virus leads to restricted EBV latency, altered phenotype, and increased tumorigenicity without affecting TCL1 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370696.RAYKuaS-OM83DlIRDJE1xx3L2_uBkawmlmRKB_xmrJjNg130_provenance.
- NP370704.RAfDKlMtz00odtNdl0wFfXkINv4srtW_xw5o9jWfAC2_o130_assertion description "[LMO2 was detected in all cases of HL (100%), in nine cases of BL (90%) and in all cases of DLBCL of germinal center (GC) subtype 20/35 (57.1%) but is completely negative in non-germinal center (NGC) DLBCL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370704.RAfDKlMtz00odtNdl0wFfXkINv4srtW_xw5o9jWfAC2_o130_provenance.
- NP370707.RAeGzqBDFz-B02ijdl58rWatB2RNT4PSQYjTjfBwmStz8130_assertion description "[Mutations in KATP channel genes (KCNJ11, ABCC8) and the insulin gene (INS) are the most common causes of PNDM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370707.RAeGzqBDFz-B02ijdl58rWatB2RNT4PSQYjTjfBwmStz8130_provenance.
- NP370713.RAU91ch9GJfwk3m8qBN_wa7JEpa4lFc-ZFLG4nqOZaCgE130_assertion description "[CDH1 expression is down-modulated in invasive lobular breast carcinomas but its regulation in invasive ductal carcinomas (IDC) is less clear.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370713.RAU91ch9GJfwk3m8qBN_wa7JEpa4lFc-ZFLG4nqOZaCgE130_provenance.
- NP370715.RAWX_H9I2JKw4H66xDE8StfA2cOXbIuBC3hf0uww3G4yg130_assertion description "[In this study we have investigated the significance of CYP3A4*1B and CYP2D6*4 polymorphisms in TD susceptibility among chronic schizophrenia patients (n = 335) from north India.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370715.RAWX_H9I2JKw4H66xDE8StfA2cOXbIuBC3hf0uww3G4yg130_provenance.
- NP370722.RAbp2RSxmX25gc1l3plmompuK4qO9BlcIpvC-92Q3Biso130_assertion description "[Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant and age-dependent vascular disorder characterised mainly by mutations in the Endoglin (ENG) or activin receptor-like kinase-1 (ALK1, ACVRL1) genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370722.RAbp2RSxmX25gc1l3plmompuK4qO9BlcIpvC-92Q3Biso130_provenance.
- NP370727.RAfO5RACR69RVUsgWpzyMsLH3sAOU3n-OwMtBs8de0iNM130_assertion description "[Three MDR-1 genetic markers were analyzed in 108 children diagnosed with SRNS and in 135 healthy controls with neither allergic nor renal disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370727.RAfO5RACR69RVUsgWpzyMsLH3sAOU3n-OwMtBs8de0iNM130_provenance.
- NP370729.RAWbo_jgsj7nd3g8OqFGYiWWxIDxTYx8CwjbV8vg9-ptA130_assertion description "[To investigate the etiologic potential of Borna disease virus (BDV) in these disorders, two populations were studied: (1) 27 prospectively identified patients with various neurological disorders were evaluated with BDV RT-PCR (CSF, PBMC), and BDV serology, and (2) a separate group of 25 retrospectively studied patients with AIDS dementia complex was evaluated using BDV serology only.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370729.RAWbo_jgsj7nd3g8OqFGYiWWxIDxTYx8CwjbV8vg9-ptA130_provenance.
- NP370734.RAXJctJuD1GDbJkdGiyha1XHXzHB5k25omjn6LzEupp-o130_assertion description "[Furthermore, we develop a clinically relevant ATP site inhibitor of mTOR, INK128, which reprograms this gene expression signature with therapeutic benefit for prostate cancer metastasis, for which there is presently no cure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370734.RAXJctJuD1GDbJkdGiyha1XHXzHB5k25omjn6LzEupp-o130_provenance.
- NP370735.RAf_Pki7hYcF_SgjqAgr_469Fzaqra-2ss8namL9Xs9r0130_assertion description "[This case goes against dogma that mothers of severely affected sons are asymptomatic as adults and expands the differential diagnosis of primary progressive multiple sclerosis to include proteolipid protein 1 gene mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370735.RAf_Pki7hYcF_SgjqAgr_469Fzaqra-2ss8namL9Xs9r0130_provenance.
- NP370740.RAUPF7n7sQWZ5RPtmAPIj88Os6aknrsbQWAOzffjLsl0s130_assertion description "[To investigate the genetic basis for RSV disease severity, linked variants of 3 Th2 cytokine genes, IL4, IL13, and IL5 (which are clustered on chromosome 5q31.1) were characterized in 105 children who were hospitalized with severe RSV infection and 315 Korean control subjects in a pilot study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370740.RAUPF7n7sQWZ5RPtmAPIj88Os6aknrsbQWAOzffjLsl0s130_provenance.
- NP370744.RAWVw3SaelIuiTnWCDob6Z-hit0dxIkTxWyE_9v0-OsZQ130_assertion description "[In conclusions, the dominancy of PR form B mRNA expression might be associated with the expression of a malignant phenotype in gynecologic cancers, and advanced clinical stage in ovarian cancers, suggesting a biological marker of malignant phenotype in these three types of cancer cell.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370744.RAWVw3SaelIuiTnWCDob6Z-hit0dxIkTxWyE_9v0-OsZQ130_provenance.
- NP370745.RAbCie7ZBoUYA7Hkh9QLNrp6MAzpA22yJXO3gAHxGKM4s130_assertion description "[Expression silencing through CpG island methylation of DAP-kinase has been frequently found in connection with adverse survival, as cells lacking DAP-kinase appear to be more invasive and more metastatic in lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370745.RAbCie7ZBoUYA7Hkh9QLNrp6MAzpA22yJXO3gAHxGKM4s130_provenance.
- NP370747.RAXt4GR_B1fCfNLO7cPSGdg9RahTufrCtcJuyIX66rqmE130_assertion description "[These results unveil a critical role for TGF-β1 in the progression of mucoepidermoid carcinomas and suggest that patients with this malignancy may benefit from therapeutic inhibition of the effectors of the TGF-β1 pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370747.RAXt4GR_B1fCfNLO7cPSGdg9RahTufrCtcJuyIX66rqmE130_provenance.
- NP370750.RAahVELILyEyhluN4nUN8yxrPLyEAnXD6pvLegEK2ID84130_assertion description "[Three major criteria, saccade amplitude, saccade velocity, and presence of gaze-evoked nystagmus, permitted the correct assignment of 90% of the SCA1, 90% of the SCA2, and 93% of the patients with SCA3 to their genetically confirmed patient group and, therefore, may help orient diagnoses of SCA1, SCA2, and SCA3 at early clinical stages of the diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370750.RAahVELILyEyhluN4nUN8yxrPLyEAnXD6pvLegEK2ID84130_provenance.
- NP370751.RAbcwRMcWnH8X-Tfc7nm45mffMHEAMLRFgXEi6YvdNJno130_assertion description "[An m.9856T>C (Ile217Thr) mutation in MT-CO3 from one LVNC patient was found to be a non-haplogroup associated variant, and was rare in the mtDB Human Mitochondrial Genome Database, suggesting that the variant may be pathogenic.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370751.RAbcwRMcWnH8X-Tfc7nm45mffMHEAMLRFgXEi6YvdNJno130_provenance.
- NP370753.RATlUnJrbxvDf5tTauamQ502SJ573N-MkGh9HTNhE1cG4130_assertion description "[The role of inflammatory signaling is discussed and TLR4 signaling, IL-1β, TNFα and IL-6 expression appears to coincide with the development of heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370753.RATlUnJrbxvDf5tTauamQ502SJ573N-MkGh9HTNhE1cG4130_provenance.
- NP370756.RAaal5ZOYFB0ICtINFaMX_S40xGUgNU8ZcGYGeIzOMDKo130_assertion description "[In these cell lines the increased activity of the androgen responsive reporter gene (MMTV-CAT) by 1 nM MPA was fully (MDA-MB-453, CV-1) or partially (ZR-75-1) inhibited by co-culture with 1 microM anandron.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370756.RAaal5ZOYFB0ICtINFaMX_S40xGUgNU8ZcGYGeIzOMDKo130_provenance.
- NP370758.RAa1VA06l1NkfVjet_OCM7uNL1hs_ZItt9JL0pdE9h1b0130_assertion description "[We studied the effect of biologically relevant doses (comparable to 2-3 MED (minimal erythemal dose) for in vivo irradiated full-thickness skin) of monochromatic UVB light of 302 nm on cultured melanocytes derived from foreskin, common melanocytic nevi, and dysplastic nevi.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370758.RAa1VA06l1NkfVjet_OCM7uNL1hs_ZItt9JL0pdE9h1b0130_provenance.
- NP370764.RAfKN93YHwX5nL-lu3P2vlB_BK9Rz6Sq7NvDJe9CeZ9F0130_assertion description "[In conclusion, MPO polymorphisms were associated with the extent of brain damage and the functional outcome rather than with the risk of developing a BI.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370764.RAfKN93YHwX5nL-lu3P2vlB_BK9Rz6Sq7NvDJe9CeZ9F0130_provenance.
- NP370775.RAcUktKB08SmfyOv4-HngfHZuvIsNSFhpwqphBPkAU3qc130_assertion description "[Patients who had CD117-negative GIST had similar TTP but inferior OS compared with patients who had CD117-positive disease, which suggests that patients who have CD117-negative GIST may benefit from imatinib treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370775.RAcUktKB08SmfyOv4-HngfHZuvIsNSFhpwqphBPkAU3qc130_provenance.
- NP370778.RAWdDO_C6Ue6Ed8Kotn4LiFk18HDqzEBASWx-7DgqSPIc130_assertion description "[The TRAP assay revealed moderate telomerase activity in all uveal melanomas examined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370778.RAWdDO_C6Ue6Ed8Kotn4LiFk18HDqzEBASWx-7DgqSPIc130_provenance.
- NP370779.RAaejIfxk88qM7kn9vFWkFQHy7dNbtvhDW_SOwEBV_AKU130_assertion description "[Previously, we reported MAFIP can inhibit the growth of human cervical cancer HeLa cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370779.RAaejIfxk88qM7kn9vFWkFQHy7dNbtvhDW_SOwEBV_AKU130_provenance.
- NP370787.RAYigeaty9Rr5lXeAgVUtJglhzU09Cv4xoJnS7b1mblr4130_assertion description "[Mutations in the transactive response DNA binding protein-43 (TARDBP/TDP-43) gene, which regulates transcription and splicing, causes a familial form of amyotrophic lateral sclerosis (ALS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370787.RAYigeaty9Rr5lXeAgVUtJglhzU09Cv4xoJnS7b1mblr4130_provenance.
- NP370795.RAS5b6-Nz-4V335RWXwXVsSA6-c0hDTtRNUUSNr7mS2bk130_assertion description "[Heterozygous nonsense mutations in the CDSN gene encoding corneodesmosin (CDSN), an adhesive protein expressed in cornified epithelia and hair follicles, cause hypotrichosis simplex of the scalp (HSS), a nonsyndromic form of alopecia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370795.RAS5b6-Nz-4V335RWXwXVsSA6-c0hDTtRNUUSNr7mS2bk130_provenance.
- NP370796.RAfGsEtTpuk5yzR5MBaiZGqYMFaVJnRnJf-QFoQTCXsbc130_assertion description "[In a previous genome-wide association study, the SNP variants rs13429458, rs12478601, rs2479106, rs10818854 and rs13405728 in the THADA, DENND1A and LHCGR genes were identified as being independently associated with PCOS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370796.RAfGsEtTpuk5yzR5MBaiZGqYMFaVJnRnJf-QFoQTCXsbc130_provenance.
- NP370801.RAZ10mLav0v_VXPpC9Cy4v3vuDIOKb8yudZoTxOl8j0fA130_assertion description "[We compared the genotype frequencies for the CYP3A5*3, the CYP3A4*1B and the NQO1609C-->T substitution in 224 children with ALL who did not develop t-ML (controls) and in 53 children with ALL who did develop the complication.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370801.RAZ10mLav0v_VXPpC9Cy4v3vuDIOKb8yudZoTxOl8j0fA130_provenance.
- NP370807.RAbHPO0O2JbBsrJMJjEHiNivO12MiulWYUHcEKBtcgroU130_assertion description "[The p160 nuclear receptor coactivator, AIB1 (amplified in breast cancer 1), is frequently overexpressed in human breast cancer and has been shown to be associated with tamoxifen resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370807.RAbHPO0O2JbBsrJMJjEHiNivO12MiulWYUHcEKBtcgroU130_provenance.
- NP370812.RAWuHIDDEIPYpAGvT5sddsCfpUgIuZtsekR6xVmHJ4b-M130_assertion description "[Clinical examination of the family and linkage analysis using markers flanking COL2A1 and COL11A1, the known loci for Stickler syndrome; mutation screening of COL2A1; construction of splicing reporter minigenes and transfection into cultured cells; and RT-PCR analysis of reporter specific transcripts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370812.RAWuHIDDEIPYpAGvT5sddsCfpUgIuZtsekR6xVmHJ4b-M130_provenance.
- NP370816.RAcHgfxkFHfS2n4dhmXfmZSJyjhSBmjZMmHaQPAxI_neQ130_assertion description "[Based on quantitative PCR analyses of DNA, unlike other ETS fusions described in prostate cancer, the expression of SLC45A3-ELK4 mRNA is not exclusive to cases harboring a chromosomal rearrangement.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370816.RAcHgfxkFHfS2n4dhmXfmZSJyjhSBmjZMmHaQPAxI_neQ130_provenance.
- NP370820.RATbCCiXcOYf5eMagJEb2_Y9Wz3sZr6A8da7r0rww947M130_assertion description "[Finally, after statin treatment in children with FH (n = 10), mRNA levels of OX40L and TRAILR1 decreased, whereas levels BAFF, TRAIL and TRAILR3 increased.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370820.RATbCCiXcOYf5eMagJEb2_Y9Wz3sZr6A8da7r0rww947M130_provenance.
- NP370823.RATwChcFt86Ft1TKAU7j0BP4xlVq5yM5Sb9LerZj28T3w130_assertion description "[Mutation of DNAJC19, a human homologue of yeast inner mitochondrial membrane co-chaperones, causes DCMA syndrome, a novel autosomal recessive Barth syndrome-like condition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370823.RATwChcFt86Ft1TKAU7j0BP4xlVq5yM5Sb9LerZj28T3w130_provenance.
- NP370824.RAShx2H3lfom1yvkVxATyA7_Nk2q9lDuYaAs-EQkoVopc130_assertion description "[It promoted apoptosis in two CD7-positive cell lines derived from T-lineage acute lymphoblastic leukemias, CEM and Jurkat, but not in the CD7-negative B-lymphoid lines REH, Nalm-6, and SEM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370824.RAShx2H3lfom1yvkVxATyA7_Nk2q9lDuYaAs-EQkoVopc130_provenance.
- NP370826.RAVzQdxU34K5v_MuDFEEGIBZqkkqlVIuW-_xLQRL3RNMM130_assertion description "[These findings extend the phenotype associated with the PRKAG2 gene and emphasize an additional cause of familial conduction defect.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370826.RAVzQdxU34K5v_MuDFEEGIBZqkkqlVIuW-_xLQRL3RNMM130_provenance.
- NP370829.RAfh6aZJ7uuhKTXHh9BlkGcDO5nXQQWGNydPpi10g_NDw130_assertion description "[Eight weeks after subcutaneous inoculation of these cells into nude mice, CAT activity was detected in regional lymph nodes, femurs, lungs, and brain, thereby mimicking the organ tropism observed for naturally occurring metastases of prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370829.RAfh6aZJ7uuhKTXHh9BlkGcDO5nXQQWGNydPpi10g_NDw130_provenance.
- NP370830.RAdDn1BSDillLIsP_o-iEu7f1rW_Sc9iTfNxCkvSVis38130_assertion description "[This case of GACI was independent of mutations in the ENPP1 gene but was probably related to ABCC6 mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370830.RAdDn1BSDillLIsP_o-iEu7f1rW_Sc9iTfNxCkvSVis38130_provenance.
- NP370841.RASEwI_QIwVyNd45nDWpe4qKsO3yC-7FWqq-2PruOvd-w130_assertion description "[BMD patients were studied using optical coherence tomography (OCT) to understand the disease process in the macula leading to vision loss.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370841.RASEwI_QIwVyNd45nDWpe4qKsO3yC-7FWqq-2PruOvd-w130_provenance.
- NP370842.RAU4P9qJD26LX9_7Dl03tBQV5D3TaYR4maZOK--7jDoRY130_assertion description "[Tetramer staining showed that (1) by direct staining of single sample and flow cytometric analyses, detection of tetramer-positive CD4(+) T cells ranged from 0.1% to 8.8% (median 0.67% in tetramer 1 and 0.5% in tetramer 2), 0.1 to 10.7% (0.74% and 0.71%), 0.02 to 2.2% (0.25% and 0.25%), 0.02 to 0.48% (0.2% and 0.2%) and most at under 0-0.2% (0.2% and 0.16%) in the initial pulmonary TB (PTB) patients' blood, pleural fluid (PLF) of initial tuberculous pleuritis patients, non-TB patients' blood, healthy donors' blood and umbilical cord blood, respectively; significantly higher levels of CD4(+) T cells were detected in samples of TB patients than in three control donor groups; (2) by direct staining of time point TB samples and flow cytometric analyses, along with TB symptom amendment at day 60, tetramer-positive CD4(+) T cells began to decrease, until after 90-120 days, reached and kept at a relatively low even normal level about at 0.03-0.3%; (3) by enrichment approach, at least 10-fold increased memory tetramer-positive CD4(+) T cells were seen; (4) by in situ staining, tetramer-positive, IFN-γ-producing and/or TNF-α-producing CD4(+) T cells in the lymph node and lung granuloma and cavernous tissues of TB patients could be determined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370842.RAU4P9qJD26LX9_7Dl03tBQV5D3TaYR4maZOK--7jDoRY130_provenance.
- NP370843.RARcdwaPh1wv8Ce47l4PKzHt0eoIgXpVdfdDb8CV1O27Q130_assertion description "[However, the relationship between FOXF2 expression and breast cancer progression, metastasis, and prognosis, remains to be elucidated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370843.RARcdwaPh1wv8Ce47l4PKzHt0eoIgXpVdfdDb8CV1O27Q130_provenance.
- NP370846.RATqu8O6hg6aCfH4mK-pn5cz0PX9k2fvk0h7bLvPwBhZM130_assertion description "[Combined study of in situ hybridization and immunohistochemistry revealed that OC RNA was highly expressed in prostate tumor epithelial cells while only very low levels of protein were detected, which confirms that there are OC RNA variants in non-osseous tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370846.RATqu8O6hg6aCfH4mK-pn5cz0PX9k2fvk0h7bLvPwBhZM130_provenance.
- NP370848.RAZMf6H8r_pvZzA-XOhWXo2oJ1sGmFaNC53us4D8e-ieE130_assertion description "[Alpha-interferon (IFN) has been used to treat hepatitis B virus carriers with chronic hepatitis Delta virus superinfection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370848.RAZMf6H8r_pvZzA-XOhWXo2oJ1sGmFaNC53us4D8e-ieE130_provenance.
- NP370850.RAcAeTtRUo-KSzL-l3vfVBoTYwWMESIdjq_I50LKFNjzQ130_assertion description "[Our results demonstrate that CREB promotes melanoma growth and metastasis by down-regulating CCN1/CYR61 expression, which acts as a suppressor of melanoma cell motility, invasion and angiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370850.RAcAeTtRUo-KSzL-l3vfVBoTYwWMESIdjq_I50LKFNjzQ130_provenance.
- NP370852.RAX1m1Zy7RQyOgV-3pboACl38w8ZYshWjfhHY9JXlfJSk130_assertion description "[To make an ultrastructural comparison of superficial temporal artery (STA) biopsy specimens from patients with spontaneous cervical artery dissection (sCAD) and controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370852.RAX1m1Zy7RQyOgV-3pboACl38w8ZYshWjfhHY9JXlfJSk130_provenance.
- NP370857.RARXdg-HGZiXFP5UL0c-7IVQE0HGgTbREg8fAL0HJIxxk130_assertion description "[HPA phenotypes form a spectrum ranging from classical phenylketonuria (PKU) to mild hyperphenylalaninemia (MHP).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370857.RARXdg-HGZiXFP5UL0c-7IVQE0HGgTbREg8fAL0HJIxxk130_provenance.
- NP370864.RAdlJRzHWnuKGXxpa_9HIH9xwD7T9kITHFwXZAdOZy5Ww130_assertion description "[For this study, we recruited patients with chronic lower-limb ischemia and atherosclerotic infrainguinal occlusion or stenosis suitable for PTA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370864.RAdlJRzHWnuKGXxpa_9HIH9xwD7T9kITHFwXZAdOZy5Ww130_provenance.
- NP370868.RAfojIux8aBdIuT2pyDbzHcyMH5jsQC-iLi3TZOgFGH3M130_assertion description "[We show that genes encoding the inhibitory NK cell receptor KIR2DL3 and its human leukocyte antigen C group 1 (HLA-C1) ligand directly influence resolution of hepatitis C virus (HCV) infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370868.RAfojIux8aBdIuT2pyDbzHcyMH5jsQC-iLi3TZOgFGH3M130_provenance.
- NP370870.RASQp3i7EBBnNF182m06H59HxbLzCsfV0I5_0wk_YPtmQ130_assertion description "[Eighteen single nucleotide polymorphisms (SNPs) were genotyped in TLR2 (2), TLR4 (12) and CD14 (4) in 700 T1D children, 357 nuclear families with T1D children and 796 children from the 'Environment and Childhood Asthma' study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370870.RASQp3i7EBBnNF182m06H59HxbLzCsfV0I5_0wk_YPtmQ130_provenance.
- NP370876.RAbHsKvOjiKlmsCBQByWeV-LRsC_xtTkFzMiASkmiSBa0130_assertion description "[ESR1 in myocardial infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370876.RAbHsKvOjiKlmsCBQByWeV-LRsC_xtTkFzMiASkmiSBa0130_provenance.
- NP370880.RAZY2NHoTChyPJqmCBWTd4bGtsUita_IOm4X1qLpNNI5E130_assertion description "[The proteins involved in DDR pathways exhibited differential expression between squamous cell carcinoma and adenocarcinoma and were important determinants of survival in stage I squamous cell carcinoma patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370880.RAZY2NHoTChyPJqmCBWTd4bGtsUita_IOm4X1qLpNNI5E130_provenance.
- NP370899.RAYT-NDlckN1AJ3CUKI3bPCbymb045K0sWERXVLnvu_9M130_assertion description "[Since imprinted genes tend to be grouped in clusters, we investigated the imprinting status of the dopa-decarboxylase gene (DDC) and the Cordon-bleu gene (COBL) which flank GRB10 within the 7p11.2-p13 SRS duplicated region.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370899.RAYT-NDlckN1AJ3CUKI3bPCbymb045K0sWERXVLnvu_9M130_provenance.
- NP370903.RAVVo1fzJSyDQVTg8rkxMd81yuXwD4MQaL24PwAPeEE7Q130_assertion description "[Many resource limited settings (RLS) suffer from high rates of both cervical cancer and HIV.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370903.RAVVo1fzJSyDQVTg8rkxMd81yuXwD4MQaL24PwAPeEE7Q130_provenance.
- NP370905.RAW0oOmHIqYVH3iXyRdSizegv7d6gRXeICFriJokSrf7k130_assertion description "[This study investigated the distribution of Ha-ras alleles in 40 members of hereditary non-polyposis colorectal carcinoma (HNPCC) families and in 34 cancer free subjects (spouses).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370905.RAW0oOmHIqYVH3iXyRdSizegv7d6gRXeICFriJokSrf7k130_provenance.
- NP370910.RASWbmwhAWMGvlUmqDrPPhqrsIM1m8GbqC5n0d6tzYHyQ130_assertion description "[Polymorphism in the HO-1 gene promoter was shown to be associated with susceptibility to pulmonary emphysema and restenosis after angioplasty.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370910.RASWbmwhAWMGvlUmqDrPPhqrsIM1m8GbqC5n0d6tzYHyQ130_provenance.
- NP370911.RAfygK-7rAoF-FHU4HoebAFFTdDdJyG3Hf4oYorWZNLe0130_assertion description "[Here, we investigated the tumor specificity of both MK and COX-2 promoters in human pancreatic cancer, with the aim to improve the selectivity of therapeutic gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370911.RAfygK-7rAoF-FHU4HoebAFFTdDdJyG3Hf4oYorWZNLe0130_provenance.
- NP370920.RARc9_v5GSfZ_fev9s-rxAP07_NGHAFSZ-HKDFP16HDSs130_assertion description "[As controversy exists regarding the prognostic significance of genomic rearrangements of CRLF2 in pediatric B-precursor acute lymphoblastic leukemia (ALL) classified as standard/intermediate-risk (SR) or high-risk (HR), we assessed the prognostic significance of CRLF2 mRNA expression, CRLF2 genomic lesions (IGH@-CRLF2, P2RY8-CRLF2, CRLF2 F232C), deletion/mutation in genes frequently associated with high CRLF2 expression (IKZF1, JAK, IL7R), and minimal residual disease (MRD) in 1061 pediatric ALL patients (499 HR and 562 SR) on COG Trials P9905/P9906.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370920.RARc9_v5GSfZ_fev9s-rxAP07_NGHAFSZ-HKDFP16HDSs130_provenance.
- NP370921.RAZs6oVYHgdiW41OI5p97n3xpmmuqC_ZI5T3_Z1gjeYl4130_assertion description "[Our previous work has implicated aldose reductase in a pathway whereby aldose reductase-induced use of nicotinamide adenine dinucleotide phosphate (reduced form) (NADPH) drives the pentose phosphate pathway, which culminates in a protein kinase C-induced increase in glomerular prostaglandin production and loss of mesangial cell contractility as a possible cause of hyperfiltration and glomerular dysfunction in diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370921.RAZs6oVYHgdiW41OI5p97n3xpmmuqC_ZI5T3_Z1gjeYl4130_provenance.
- NP370924.RAaSrGyOah7C6JAavIp05kNs-ZlXgY0AItZdGmNdRPxms130_assertion description "[Previous association studies of breast cancer and BRCA2 N372H and functional observations for APEX D148E ran counter to our findings of decreased risks.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370924.RAaSrGyOah7C6JAavIp05kNs-ZlXgY0AItZdGmNdRPxms130_provenance.
- NP370928.RAejrJHRU4EG6N9QM1icbWrilPdUKKJzC7P-3faiJEEmQ130_assertion description "[The BCR-ABL fusion gene is important for the leukemogenesis of chronic myeloid leukemia (CML).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370928.RAejrJHRU4EG6N9QM1icbWrilPdUKKJzC7P-3faiJEEmQ130_provenance.
- NP370935.RAcLmY-XYcpXKOLTwFZKfV_c8XBjIXUeVajfv7x5rPxuM130_assertion description "[The crucial role of FLNA on D2R was demonstrated by experiments showing that: 1) FLNA silencing in DA-sensitive prolactinomas resulted in 60% reduction of D2R expression and abrogation of DA-induced inhibition of prolactin release and antiproliferative signals, these results being replicated in MMQ cells that endogenously express FLNA and D2R; and 2) FLNA overexpression in DA-resistant prolactinomas restored D2R expression and prolactin responsiveness to DA, whereas this manipulation was ineffective in GH3 cells that express FLNA but not D2R.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370935.RAcLmY-XYcpXKOLTwFZKfV_c8XBjIXUeVajfv7x5rPxuM130_provenance.
- NP370941.RAcxTJtgF5SXRqR0bV-Qay8W9tZgQkmsYVfwwWcWeQVJA130_assertion description "[In the present study, to obtain a more pronounced outcome, we assessed the potential synergistic effect of the simultaneous gene transfer of hPEDF and human fibroblast growth factor-2 (hFGF-2) by improved third-generation SIV on RCS rats and retinal degeneration slow (rds) mice, because the former targets the primary neurons, including photoreceptor cells (PCs), whereas the latter is effective for targeting secondary neural cells, including Muller cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370941.RAcxTJtgF5SXRqR0bV-Qay8W9tZgQkmsYVfwwWcWeQVJA130_provenance.
- NP370946.RAQswd0yFnLX0wWjQenMA4LChhzMXIuGu26ThlePWcsaQ130_assertion description "[Patients with congenital long QT syndrome due to potassium channel mutations (LQT1 and LQT2) may elude diagnosis due to normal electrocardiographic findings at rest, yet remain at risk of sudden death during bradycardia or sympathetic stimulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370946.RAQswd0yFnLX0wWjQenMA4LChhzMXIuGu26ThlePWcsaQ130_provenance.
- NP370947.RAYf_E3UkhBThqyubEMJaCHceiZTauzWVKgK40fOOTgbw130_assertion description "[The angiotensinogen gene in adipose tissue might be involved in the development of upper-body obesity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370947.RAYf_E3UkhBThqyubEMJaCHceiZTauzWVKgK40fOOTgbw130_provenance.
- NP370951.RAW-CLk9C4ktliK8mJ9vcFbzOmxJmBCaSRl8OBJxkz6CI130_assertion description "[Our results indicate that MYCN and MYC regulate BMI1 gene expression at the transcriptional level and that dysregulation of the BMI1 gene mediated by MYCN or MYC overexpression, confers increased cell proliferation during neuroblastoma genesis and tumor progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370951.RAW-CLk9C4ktliK8mJ9vcFbzOmxJmBCaSRl8OBJxkz6CI130_provenance.
- NP370953.RAUYEoAGvqBlESCkLlxCsF5ou1LHbrDmc1XIu7635e4L8130_assertion description "[This study shows that cell proliferation increases and apoptosis decreases as prostate cancer progresses to androgen independence, and, that of the markers used in this study, tissue transglutaminase most accurately reflects the anticipated effect of neoadjuvant hormone therapy on localized prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370953.RAUYEoAGvqBlESCkLlxCsF5ou1LHbrDmc1XIu7635e4L8130_provenance.
- NP370955.RAVDGzy3UClXRyBSGamu01ZR5Iu2eo5khctgfDEEOLc-Q130_assertion description "[Elevated messenger RNA expression and plasma protein levels of osteopontin and matrix metalloproteinase types 2 and 9 in patients with ascending aortic aneurysms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370955.RAVDGzy3UClXRyBSGamu01ZR5Iu2eo5khctgfDEEOLc-Q130_provenance.
- NP370957.RAWKyj_9JaxmFLPOS-bBF_Dk6ixMYZ2rPVtobG88s-4Hc130_assertion description "[Realtime quantitative RT-PCR analysis of frontal lobe tissue demonstrated that increasing AD Braak Stage was associated with progressively reduced levels of mRNA corresponding to insulin, IGF-I, and IGF-II polypeptides and their receptors, tau, which is regulated by insulin and IGF-I, and the Hu D neuronal RNA binding protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370957.RAWKyj_9JaxmFLPOS-bBF_Dk6ixMYZ2rPVtobG88s-4Hc130_provenance.
- NP370964.RAdafbtx9T2xQdikcO1GQEhVGCIgA6Gj2JBoC8xKbQfio130_assertion description "[Within this critical region we have identified JAM3, a member of the junction adhesion molecule family, as a strong candidate gene for the cardiac phenotype on the basis that it is expressed during human cardiogenesis in the structures principally affected in hypoplastic left heart.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370964.RAdafbtx9T2xQdikcO1GQEhVGCIgA6Gj2JBoC8xKbQfio130_provenance.
- NP370966.RAXmEGLqGA-KynuIC6unrpDKLZwS4xMJSIlIhGW_oxmN4130_assertion description "[Our findings reveal an important role for AP-1 activation in promoting LY6K gene expression that regulates cell mobility of breast cancer cells, whereas the SNP242 C allele or methylation of the CpG site may reduce the risk of invasion or metastasis by interfering AP-1 activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370966.RAXmEGLqGA-KynuIC6unrpDKLZwS4xMJSIlIhGW_oxmN4130_provenance.
- NP370971.RAX4fniakYUCqhAwQRPjlN_rgmVlwF-ETJRhqpiD4bYHk130_assertion description "[c-N-Methyl-N'-nitro-N-nitroso-guanidine HOS transforming gene (c-MET) is a new potential drug target for treatment of patients with hepatocellular carcinoma (HCC), and a recent study of a c-MET inhibitor in such patients has shown promising results.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370971.RAX4fniakYUCqhAwQRPjlN_rgmVlwF-ETJRhqpiD4bYHk130_provenance.
- NP370981.RAalBBPmBRQ7d1o1yQUlzyhYC8qwE6cKcZg6g-aQzsCGo130_assertion description "[Cells from members of a family with acute intestinal schistosomiasis responded to schistosomal soluble egg antigen (SEA) or soluble adult worm antigen preparation (SWAP) with greater amounts of IFN-gamma than did cells from several patients with chronic intestinal schistosomiasis; IL-10 levels were similar.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370981.RAalBBPmBRQ7d1o1yQUlzyhYC8qwE6cKcZg6g-aQzsCGo130_provenance.
- NP370985.RASHkqWwocfQp3nZRM5u08jm3AmdrqupYmJJi0EfT5ZCo130_assertion description "[Advances have been made in the understanding of the genetic alterations in mucosa-associated lymphoid tissue lymphomas, including various chromosomal translocations, such as the most recently described t(3;14)(p14.1;q32) involving the FOXP1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370985.RASHkqWwocfQp3nZRM5u08jm3AmdrqupYmJJi0EfT5ZCo130_provenance.
- NP370992.RAUyEu46mdHEzFgxWhzxmusFEG0pUNHwCx6Sb0A-BR_MM130_assertion description "[One cardinal feature of Huntington's disease (HD) is the degeneration of striatal neurons, whose survival greatly depends on the binding of cortical brain-derived neurotrophic factor (BDNF) with high-affinity (TrkB) and low-affinity neurotrophin receptors [p75 pan-neurotrophin receptor (p75(NTR))].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370992.RAUyEu46mdHEzFgxWhzxmusFEG0pUNHwCx6Sb0A-BR_MM130_provenance.
- NP370999.RASuEBqHvI0sYwoMLCht-JjkVQb8XbtTLzXHlW9aDiVhg130_assertion description "[We thus show that in experimental gliomas, NUMB overexpression most likely does not exert a tumor suppressor function such as seen in epithelial cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP370999.RASuEBqHvI0sYwoMLCht-JjkVQb8XbtTLzXHlW9aDiVhg130_provenance.