Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP389750.RAcrUXMxczvKKAs9DEpk_tn4rJP_BsZeKV2-xGfVGJVxA130_assertion description "[The phospholipid-binding plasma protein beta2-glycoprotein I (beta2-GPI) is the primary antigen recognized by the circulating autoantibodies in patients with the `anti-phospholipid syndrome` (APS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389750.RAcrUXMxczvKKAs9DEpk_tn4rJP_BsZeKV2-xGfVGJVxA130_provenance.
- NP389757.RAcq-xP_cq71TIF-6lHO77s4ljy3VsRtbVFBJaEQOrC_s130_assertion description "[An artificial hyperinsulinemia, which was induced to delineate the potential interaction between elevated FFAs and hyperinsulinemia, revealed that hyperinsulinemia also increased FGF-21 levels in vivo, while rosiglitazone treatment had no effect.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389757.RAcq-xP_cq71TIF-6lHO77s4ljy3VsRtbVFBJaEQOrC_s130_provenance.
- NP389758.RAcdTzA9-fKRW4xpzCOLNzuQkYex9WbVm6gcEb_DdLDEM130_assertion description "[Aldo-keto reductase family 1 B10 (AKR1B10), a member of aldo-keto reductase superfamily, is overexpressed in human hepatocellular carcinoma, lung squamous cell carcinoma and lung adenocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389758.RAcdTzA9-fKRW4xpzCOLNzuQkYex9WbVm6gcEb_DdLDEM130_provenance.
- NP389759.RAcXPRYBbIF-OrV_61E6vcmXnsAT3Sa8DtzwPbt_Db4Uo130_assertion description "[To better understand the genetic risk factors of SLE, we investigated the associations of seven SLE susceptibility genes in a Chinese population, including FCGR3A, FCGR2A, TNFAIP3, TLR9, TREX1, ETS1 and TNIP1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389759.RAcXPRYBbIF-OrV_61E6vcmXnsAT3Sa8DtzwPbt_Db4Uo130_provenance.
- NP389771.RAVtEYGBlqiDa9mU92_GK6TGqBNbOJSmSFbR6mgRxWIwo130_assertion description "[Protein 4.1B is a 4.1/ezrin/radixin/moesin domain-containing protein whose expression is frequently lost in a variety of human tumors, including meningiomas, non-small-cell lung cancers, and breast carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389771.RAVtEYGBlqiDa9mU92_GK6TGqBNbOJSmSFbR6mgRxWIwo130_provenance.
- NP389774.RAZ3udKNTR43ZQtyRdCmjgz_t3tPpzbR6DHvIjf5exMhg130_assertion description "[Since the cloning in 1997 of SEL1L, the human ortholog of the sel-1 gene of C. elegans, most studies have focused on its role in cancer progression and have provided significant evidences to link its increased expression to a decrease in tumor aggressiveness.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389774.RAZ3udKNTR43ZQtyRdCmjgz_t3tPpzbR6DHvIjf5exMhg130_provenance.
- NP389776.RAZgv3lmgwGjG00rPD5Id3Wdli524Cfb0LUaf9hSOCk1k130_assertion description "[Thirty-five of these pedigrees (27 SA and 8 SLV) had at least 2 individuals with metabolic syndrome (216 affected individuals and 563 affected relative pairs).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389776.RAZgv3lmgwGjG00rPD5Id3Wdli524Cfb0LUaf9hSOCk1k130_provenance.
- NP389780.RAWah4U7YbCq13d91dzPDGWXFOg4RwqPSr6WV7D-Ilq4U130_assertion description "[Many cellular, preclinical, and observational studies support a role for vitamin D in the pathogenesis of both types of diabetes including: (1) T1D and T2D patients have a higher incidence of hypovitaminosis D; (2) pancreatic tissue (more specifically the insulin-producing beta-cells) as well as numerous cell types of the immune system express the vitamin D receptor (VDR) and vitamin D-binding protein (DBP); and (3) some allelic variations in genes involved in vitamin D metabolism and VDR are associated with glucose (in)tolerance, insulin secretion, and sensitivity, as well as inflammation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389780.RAWah4U7YbCq13d91dzPDGWXFOg4RwqPSr6WV7D-Ilq4U130_provenance.
- NP389782.RAe2HcO-Ty-zf9qj9tdLS3rSJ6BbhQYC-S_rC03zNlFe8130_assertion description "[In addition, the donor (but not the recipient) had a polymorphism of the 5' UTR of NOD2/CARD15 that may be associated with Crohn's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389782.RAe2HcO-Ty-zf9qj9tdLS3rSJ6BbhQYC-S_rC03zNlFe8130_provenance.
- NP389786.RAaPBoTduI3MZCx94tOgNdx-nWZw-NvH0Zgn7HNgm2dC0130_assertion description "[From FUS to Fibs: what's new in frontotemporal dementia?]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389786.RAaPBoTduI3MZCx94tOgNdx-nWZw-NvH0Zgn7HNgm2dC0130_provenance.
- NP389802.RAaCWpi_--HRFtA8dTraJHumtZlgaj5AKrbROts3d0f_8130_assertion description "[Our results implicate the human tau gene as a target gene for the alternative splicing regulator Tra2 beta, suggesting that Tra2 beta may play a role in aberrant tau exon 10 alternative splicing and in the pathogenesis of tauopathies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389802.RAaCWpi_--HRFtA8dTraJHumtZlgaj5AKrbROts3d0f_8130_provenance.
- NP389810.RAWIgQfUxKkpbPeE7R14pPziYmM-wbqSay63g2-vR40kg130_assertion description "[Animal studies with different genotoxic or nongenotoxic compounds, as organized for instance within the framework of the International Life Sciences Institute/Health and Environmental Sciences Institute program, are needed to further evaluate the suitability of the XPA model for short-term carcinogenicity testing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389810.RAWIgQfUxKkpbPeE7R14pPziYmM-wbqSay63g2-vR40kg130_provenance.
- NP389813.RAT1BeSEDVxq1h_uUqxEYq6GeAQ_ERoHHbmfcs1Aqua9c130_assertion description "[Our study provides suggestive evidence for greater brain atrophy in MS patients bearing the PCK1 allele associated with AD-susceptibility, yielding new insights into potentially shared neurodegenerative process between MS and late onset AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389813.RAT1BeSEDVxq1h_uUqxEYq6GeAQ_ERoHHbmfcs1Aqua9c130_provenance.
- NP389818.RAb8lDk0lSYd3W1QVz9_9H4MTwILY57uLNdnjB4g95WQM130_assertion description "[We found antimicrobial peptides (human cathelicidin LL-37) in the CSF of patients with bacterial meningitis but not in control CSF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389818.RAb8lDk0lSYd3W1QVz9_9H4MTwILY57uLNdnjB4g95WQM130_provenance.
- NP389838.RAShbD547x9EmVCx7OYX7MpFM6FVwwUu9awBRLyndznMA130_assertion description "[In thyroids from three RAd-treated animals, there was marked, significant inhibition of Tie2, FGFR1, VEGFR1, FGF-2, and VEGF expression, compared with control goiters.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389838.RAShbD547x9EmVCx7OYX7MpFM6FVwwUu9awBRLyndznMA130_provenance.
- NP389843.RAfNaFcOReAZbzWKr2sIBpg4NHfb5no47oksXO3NrArGc130_assertion description "[The mechanism by which HDAC9 increases stroke risk is not clear; both vascular and neuronal mechanisms have been proposed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389843.RAfNaFcOReAZbzWKr2sIBpg4NHfb5no47oksXO3NrArGc130_provenance.
- NP389844.RAZBxiCnUbpSbsJEolvJF2YS-K4INgZKyB9R9ny-TJkiI130_assertion description "[Glutathione s-transferase (GST) polymorphisms (GSTM1, GSTP1 and GSTT1) have been considered as risk factors for developing acute leukaemia in a number of studies; however the overall results of such studies are inconsistent.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389844.RAZBxiCnUbpSbsJEolvJF2YS-K4INgZKyB9R9ny-TJkiI130_provenance.
- NP389846.RAQ4kbTkLiGvGXUx2YivAO1kTTgQvq3bDSFxfWL8k5YzY130_assertion description "[BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389846.RAQ4kbTkLiGvGXUx2YivAO1kTTgQvq3bDSFxfWL8k5YzY130_provenance.
- NP389849.RAbirn4l8Ntr9QC0lDzvuGeHuTMjH4OBJdUHWu1A1tzLQ130_assertion description "[Autoantibodies were also detected against chromodomain-helicase-DNA binding protein 8, presynaptic cytomatrix protein (piccolo), Ca(2+)-dependent secretion activator, PGSF2 and NSE in serum samples from patients with lymphocytic hypophysitis, but at a frequency that did not differ from healthy controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389849.RAbirn4l8Ntr9QC0lDzvuGeHuTMjH4OBJdUHWu1A1tzLQ130_provenance.
- NP389856.RATCIvVg8zCS8e0u8SPQg9QPgLxxze5y7LRflXZnasqcg130_assertion description "[Once transformed, the impairment turns to be a target for therapy as exemplified by the synthetic lethal strategy such as poly (ADP-ribose) polymerase (PARP) inhibitor for BRCA1/2-defective breast and ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389856.RATCIvVg8zCS8e0u8SPQg9QPgLxxze5y7LRflXZnasqcg130_provenance.
- NP389863.RAY6tBNBxbtGk_c1shV2m56Pa-J2a8VAOPHkyahejjmmw130_assertion description "[The identification of ADAM33 as a psoriasis susceptibility gene identified by positional cloning in an outbred population should provide insights into the pathogenesis and natural history of this common disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389863.RAY6tBNBxbtGk_c1shV2m56Pa-J2a8VAOPHkyahejjmmw130_provenance.
- NP389864.RAXEQE1wpDaeSTwV9C6hhtc7fKMTGE8jkw0HWbv6uFyvY130_assertion description "[Laing early onset distal myopathy (MPD1) is an autosomal dominant myopathy caused by mutations within the slow skeletal muscle fibre myosin heavy chain gene, MYH7.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389864.RAXEQE1wpDaeSTwV9C6hhtc7fKMTGE8jkw0HWbv6uFyvY130_provenance.
- NP389876.RAamjhQPR3YTHFZY4-ZZY8h3Iy0ZDPmcIs0oxnuwL8lsQ130_assertion description "[In this study, we investigated the prevalence of human papilloma virus (HPV) infection and TP53 expression in patients with squamous cell carcinoma (SCC) of the tongue and, subsequently, its significance in cervical lymph node metastases and tumor differentiation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389876.RAamjhQPR3YTHFZY4-ZZY8h3Iy0ZDPmcIs0oxnuwL8lsQ130_provenance.
- NP389878.RAU8MYW0uQ9LVYV4fh2GTB5f3KDKdUAcQXn7SyV8tYnRQ130_assertion description "[Association between schizophrenia and a microsatellite polymorphism at the dopamine D5 receptor gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389878.RAU8MYW0uQ9LVYV4fh2GTB5f3KDKdUAcQXn7SyV8tYnRQ130_provenance.
- NP389879.RAYTsBUexgXLy8SdFGB_haqYwWSh6XKVaIgM35JhypSu0130_assertion description "[The immunocytochemical study of thrombomodulin (TM), a newly recognized anticoagulant endothelial surface protein, was performed with a surgical specimen of a superficial temporal artery (STA) obtained from a 29-year-old woman with familial moyamoya disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389879.RAYTsBUexgXLy8SdFGB_haqYwWSh6XKVaIgM35JhypSu0130_provenance.
- NP389880.RAZRJLVuQcuTDuJYGt4NCsJ0GLUJe0NHv7Z6xMnyJbSWg130_assertion description "[Consistent with preclinical findings, a synonymous CNR1 polymorphism, rs1049353, is linked to the effects of stress attributable to childhood physical abuse on anhedonia and anhedonic depression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389880.RAZRJLVuQcuTDuJYGt4NCsJ0GLUJe0NHv7Z6xMnyJbSWg130_provenance.
- NP389886.RAURjRkOcZzhvws7JixbmWQUwbYaowtMbbWe2m5i2P3Xk130_assertion description "[In total, 109 of 238 (45.8 %) specimens were culture-positive for Mycobacterium tuberculosis complex (MTBC), and, of these, 67 isolates were rifampicin resistant (RIF-R) by phenotypic DST and 64/67 (95.5 %) were isoniazid resistant (INH-R).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389886.RAURjRkOcZzhvws7JixbmWQUwbYaowtMbbWe2m5i2P3Xk130_provenance.
- NP389890.RARvyZRWa1DsYmdVlzO-EPjChXVBP8iAEcW8nS6SaQ3G4130_assertion description "[Soluble IL-4R regulates the bioactivity of IL-4, a cytokine important in mediating progressive forms of leishmaniasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389890.RARvyZRWa1DsYmdVlzO-EPjChXVBP8iAEcW8nS6SaQ3G4130_provenance.
- NP389891.RASl6S0F-Bz2t46C9B5AHqPOU5Vzq7yIw98wM8JpS26HM130_assertion description "[The relationship between selenium (Se) deficiency and insulin resistance has not much been established in persistent hepatitis C virus (HCV) infection, although Se deficiency is often observed in patients with liver cirrhosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389891.RASl6S0F-Bz2t46C9B5AHqPOU5Vzq7yIw98wM8JpS26HM130_provenance.
- NP389894.RAWzkuGdeSTKyNqnZhjKF8T0u1pRTkte4aRKwnf6YpLnY130_assertion description "[We have previously shown that human colorectal cancer tissue is able to inactivate the anticancer drug paclitaxel through cytochrome P450 (CYP)2C8 and CYP3A4 metabolisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389894.RAWzkuGdeSTKyNqnZhjKF8T0u1pRTkte4aRKwnf6YpLnY130_provenance.
- NP389906.RAXZn9B3EYrfh6KATYbAFdy39hW7xsCla_sf-LbJ2Dyjg130_assertion description "[NOR1 is an HSF1- and NRF1-regulated putative tumor suppressor inactivated by promoter hypermethylation in nasopharyngeal carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389906.RAXZn9B3EYrfh6KATYbAFdy39hW7xsCla_sf-LbJ2Dyjg130_provenance.
- NP389907.RAXmwWTVc6QpDrgsIAXhjhzOHkP0qA7y16on8WyLF1XZs130_assertion description "[However, the association of AEDs-induced mild maculopapular eruption (MPE) with HLA-B*1502 remains unclear until recently.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389907.RAXmwWTVc6QpDrgsIAXhjhzOHkP0qA7y16on8WyLF1XZs130_provenance.
- NP389908.RAVSGlhGQRLa6HeUG4IBjLDHgba2ZbHtvdh8rQtXbl2F4130_assertion description "[Each patient was scanned using HH SD-OCT (Bioptigen Inc., Research Triangle Park, NC) without sedation, and foveal morphology was classified into 1 of 4 categories: (1) typical foveal hypoplasia (predicting clinical diagnosis of albinism, PAX6 mutations, or isolated foveal hypoplasia); (2) atypical foveal hypoplasia (predicting achromatopsia); (3) other foveal changes (corresponding to retinal dystrophies); and (4) normal fovea (predicting idiopathic or manifest latent nystagmus).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389908.RAVSGlhGQRLa6HeUG4IBjLDHgba2ZbHtvdh8rQtXbl2F4130_provenance.
- NP389909.RAS8dxhE_k8pZU7RYa7zDelaNT-EZbCJ4cgCKxWKQX0Gs130_assertion description "[Anti-interleukin-5 therapy for asthma and hypereosinophilic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389909.RAS8dxhE_k8pZU7RYa7zDelaNT-EZbCJ4cgCKxWKQX0Gs130_provenance.
- NP389914.RARtkj8qclNLGnpt_abnhIW26SA4KBBA1V0DxI3q1Trro130_assertion description "[In addition, Cdk4(R24C/R24C) mice showed extraordinary susceptibility to carcinogens and developed papillomas within the first 8 to 10 weeks following cutaneous application of the carcinogens 9,10-di-methyl-1,2-benz[a]anthracene (DMBA) and 12-O-tetradecanoylphorbol-13-acetate (TPA).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389914.RARtkj8qclNLGnpt_abnhIW26SA4KBBA1V0DxI3q1Trro130_provenance.
- NP389918.RAYuZsD9xnPiBBk1dQKF57sJD9G_V_RHJ8HHmFQ_hw31s130_assertion description "[The shortcoming in using Ad5 is mostly attributed to a reduction in Coxsackie-adenovirus receptors (CAR) on the surface of cancer cells, which can be mitigated by generating tropism-modified Ads permitting CAR-independent infection of tumor cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389918.RAYuZsD9xnPiBBk1dQKF57sJD9G_V_RHJ8HHmFQ_hw31s130_provenance.
- NP389922.RAZu_xGOrf-cUnuoj3vxBK1oA-FD-Hmr5er3kICOqSYaY130_assertion description "[Massive pulmonary embolism in pregnancy treated with tissue plasminogen activator.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389922.RAZu_xGOrf-cUnuoj3vxBK1oA-FD-Hmr5er3kICOqSYaY130_provenance.
- NP389924.RAWdi60BwUdOV2v2xnAk3cNUDfkv764ddeQj9zZxnOuQo130_assertion description "[Compared with HPV-negative TC, HPV-positive TC showed a strong association with p16 overexpression (p<0.0001), and an inverse association with EGFR amplification (p=0.0478).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389924.RAWdi60BwUdOV2v2xnAk3cNUDfkv764ddeQj9zZxnOuQo130_provenance.
- NP389925.RAZy9ViL-S4fK28H2r2xC1eOkYPaFDw8Yo4KnCHX2xaOk130_assertion description "[Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389925.RAZy9ViL-S4fK28H2r2xC1eOkYPaFDw8Yo4KnCHX2xaOk130_provenance.
- NP389932.RAVVW2sDwQGS1bde96cOVSdSgqgNDj8kW0WFGy5-jw-VU130_assertion description "[Impaired granulopoiesis was found in both CD34(+)/Kit(+)/G-CSFR(+) and CD34(+)/Kit(+)/G-CSFR- cells in patients with CyN, whereas this impairment was observed only in CD34(+)/Kit(+)/G-CSFR(+) cells in SCN patients, as previously reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389932.RAVVW2sDwQGS1bde96cOVSdSgqgNDj8kW0WFGy5-jw-VU130_provenance.
- NP389934.RAfi8RfzVteLn3LvthUS95HJ09tICZ9hlQa5-SLXLW_As130_assertion description "[Therefore, we analyzed 20 serous tumors of LMP, 10 invasive serous ovarian carcinomas, and 7 benign serous cystadenomas by nonisotopic in situ hybridization (seven different centromere-specific probes) as well as by flow and image DNA cytometry and compared the data with results of p53 and Ki67 immunohistochemistry, MYC DNA PCR analysis and with the clinical follow-up.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389934.RAfi8RfzVteLn3LvthUS95HJ09tICZ9hlQa5-SLXLW_As130_provenance.
- NP389937.RAYJe4qlZB0wQPBu2Apc3zhvZgbNgxg1u0D5MB1oJytb8130_assertion description "[Recent findings demonstrated that HIPK2 inhibitions do exist in tumors and depend by several mechanisms including HIPK2 cytoplasmic localization, protein degradation, and loss of heterozygosity (LOH), recapitulating the biological outcome obtained by RNA interference studies in tumor cells, such as p53 inactivation, resistance to therapies, apoptosis inhibition, and tumor progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389937.RAYJe4qlZB0wQPBu2Apc3zhvZgbNgxg1u0D5MB1oJytb8130_provenance.
- NP389941.RAdYsDULeUiuYkL6yR9Y3cZ20gCeVC5hd6BVFkCZEmv30130_assertion description "[Hence, reduced circulating levels of B6 vitamers (including PLP as well as its major precursor pyridoxine) are frequently paralleled by hyperhomocysteinemia, a condition that has been associated with an increased risk for multiple cardiovascular diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389941.RAdYsDULeUiuYkL6yR9Y3cZ20gCeVC5hd6BVFkCZEmv30130_provenance.
- NP389942.RAcqzNlBvWhDAl2GxZIS-bY3e6tJEHPosdcp-1BUUD0I0130_assertion description "[Short stature homeobox- containing (SHOX) gene defects determine a highly variable phenotype, that includes an osteochondrodysplasia with mesomelic short stature and Madelung deformity, but also presentations without evident malformations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389942.RAcqzNlBvWhDAl2GxZIS-bY3e6tJEHPosdcp-1BUUD0I0130_provenance.
- NP389944.RAWhW-RqYw-hYCmFb_UAMeG3CXdqKIKXINxRa6HD6vXNo130_assertion description "[The autosomal recessive form of type II cutis laxa (ARCL II) is characterized by the appearance of redundant, inelastic skin with wrinkling, an aged look and additional variable systemic involvement including intrauterine growth retardation, failure to thrive, developmental delay, dysmorphism, osseous abnormality, and CNS manifestations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389944.RAWhW-RqYw-hYCmFb_UAMeG3CXdqKIKXINxRa6HD6vXNo130_provenance.
- NP389952.RATckr-g4wFJqo73IM1--KWqfnXX1gqRGxEUMP0Eo19pE130_assertion description "[In this study, employing a sample of 1,873 subjects from 405 Caucasian nuclear families, we studied seven single nucleotide polymorphisms (SNPs) and their haplotypes of the ER-alpha gene for association with six hip geometric variables, namely, cross-sectional area (CSA), cortical thickness (CT), endocortical diameter (ED), subperiosteal width (W), sectional modulus (Z) and buckling ratio (BR).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389952.RATckr-g4wFJqo73IM1--KWqfnXX1gqRGxEUMP0Eo19pE130_provenance.
- NP389953.RAbp-yeQeY9ID7DlUt4Gwk3BzpK4N_Hbl8541C6vbXW5g130_assertion description "[Silencing ALCAM in miR-214-overexpressing melanoma cells reduced cell migration and invasion without affecting growth or anoikis in vitro, and it also impaired extravasation and metastasis formation in vivo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389953.RAbp-yeQeY9ID7DlUt4Gwk3BzpK4N_Hbl8541C6vbXW5g130_provenance.
- NP389954.RAZdHwGV6-59boomr1I8sLF2E0qGVgNTMOD7M1JbssEwY130_assertion description "[The DR. DQ linkage arrangements in South Indians were shown to be different for DR2, DR4, and DRw6 from those commonly seen in Europeans, so that localization of the primary disease-promoting gene in IDDM could be attempted.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389954.RAZdHwGV6-59boomr1I8sLF2E0qGVgNTMOD7M1JbssEwY130_provenance.
- NP389959.RASgdspz4jURZljU-28tCgwez8yT7qVpiJI0bsm2tubHQ130_assertion description "[A preliminary investigation of the association between haptoglobin polymorphism, serum ferritin concentration and fatty liver disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389959.RASgdspz4jURZljU-28tCgwez8yT7qVpiJI0bsm2tubHQ130_provenance.
- NP389964.RASluZMlCvQMQBq__k_B2aLp6NmaI4mAueCyUQOw9q6Cs130_assertion description "[ERB-041 is a selective estrogen receptor-beta (ERbeta) agonist that has anti-inflammatory activity in preclinical models of arthritis and inflammatory bowel disease, but is inactive in many preclinical models of classic estrogen activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389964.RASluZMlCvQMQBq__k_B2aLp6NmaI4mAueCyUQOw9q6Cs130_provenance.
- NP389965.RAXOWJu5_LqNwfj-JwLiQI8ninX5utlZeqdABWTUS7DCY130_assertion description "[Antibody and complementary DNA probes utilized for detection of the MDR1 gene product and mRNA levels, respectively, revealed that prior to drug treatment the lung tumor had virtually no detectable P-glycoprotein while both colon carcinomas displayed low and heterogeneous expression of this resistance-related protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389965.RAXOWJu5_LqNwfj-JwLiQI8ninX5utlZeqdABWTUS7DCY130_provenance.
- NP389971.RAbx1HSwxOVJbVpgKSL3A3dJ5gjiwUbYZh_2g8fHN-TXA130_assertion description "[Pseudodeficiency of arylsulphatase A: strategy for clarification of genotype in families of subjects with low ASA activity and neurological symptoms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389971.RAbx1HSwxOVJbVpgKSL3A3dJ5gjiwUbYZh_2g8fHN-TXA130_provenance.
- NP389984.RAbfdkHNaprGcfraxgpElzVg84FnBDGRPj4iU7BdBj930130_assertion description "[Two dichromats and two anomalous trichromats did not show clear evidence of LWS vs MWS cone antagonism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389984.RAbfdkHNaprGcfraxgpElzVg84FnBDGRPj4iU7BdBj930130_provenance.
- NP389986.RAbiirq7S9Hr5um2nAcV4e-6Z8y6P3lE9PCPgwNWnjci8130_assertion description "[In mid-January 1998 this student suffered a mild episode of IMD (meningitis) during which N. meningitidis was isolated from his CSF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389986.RAbiirq7S9Hr5um2nAcV4e-6Z8y6P3lE9PCPgwNWnjci8130_provenance.
- NP389993.RAbZDAiRvtxvFpRcc92IRRNzmUrOJeQKPs0V_MmYouQmk130_assertion description "[In hyperplasias and carcinomas, the expression of both membranous and cytoplasmic CD24 was found to be sharply reduced in the hyperplastic lesions and significantly enhanced in the carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP389993.RAbZDAiRvtxvFpRcc92IRRNzmUrOJeQKPs0V_MmYouQmk130_provenance.
- NP390001.RATkG0BaQP9-NekS41z_8TF9DBDD1QIspB0K1pMkj2lQY130_assertion description "[Our results suggest that two specific loci may confer a susceptibility to BQ abuse and affect MAO-A enzymatic activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390001.RATkG0BaQP9-NekS41z_8TF9DBDD1QIspB0K1pMkj2lQY130_provenance.
- NP390002.RAQ-shkXcqtYgI3nAa3smzfnw2B8nZWNSEuQkrUyvN0Ik130_assertion description "[We identified a novel single nucleotide polymorphism, -1173 C-->T, in the NOS2 promoter that was significantly associated with protection from symptomatic malaria (odds ratio 0.12, 95% CI 0.03-0.48, p=0.0006) in 179 Tanzanian children, and significantly associated with protection from severe malarial anaemia (adjusted relative risk 0.25, 95% CI 0.09-0.66, p=0.0005) in 1106 Kenyan children studied over 5 years.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390002.RAQ-shkXcqtYgI3nAa3smzfnw2B8nZWNSEuQkrUyvN0Ik130_provenance.
- NP390010.RAU-LYUKpzsZse6Vnp1XFHJzeHpaWM548pINsAt7O5-RY130_assertion description "[The spinocerebellar ataxia type 17 (SCA17) is characterized by cerebellar ataxia, dementia, and involuntary movements, including chorea and dystonia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390010.RAU-LYUKpzsZse6Vnp1XFHJzeHpaWM548pINsAt7O5-RY130_provenance.
- NP390018.RAd2KZehwwgAARVVU-cqIgIA4uWMGlBuY_7eVDhzZdmsU130_assertion description "[Silver-Russell syndrome (SRS, OMIM 180860) is a congenital disorder characterized by severe intrauterine and postnatal growth retardation, dysmorphic facial features and body asymmetry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390018.RAd2KZehwwgAARVVU-cqIgIA4uWMGlBuY_7eVDhzZdmsU130_provenance.
- NP390020.RAWQyPhuC4eur72f1PHGCuIfbwdIT8wIzzE0KRndo9WwM130_assertion description "[There have been reports of tight linkage to a number of chromosome 19 markers, including APOC2 and creatine kinase muscle type (CKMM), but they did not establish orientation of the 2 markers to DM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390020.RAWQyPhuC4eur72f1PHGCuIfbwdIT8wIzzE0KRndo9WwM130_provenance.
- NP390021.RAb86-Yp96ubBz3hFwZGWZJ6e2xksRzlXnmT2jkgyHa8U130_assertion description "[The genotoxicity and cytotoxicity of a Chinese medicinal herb, Tripterygium hypoglaucum (level) Hutch (THH), was investigated in human promyelocytic leukemia (HL-60) cells using the hypoxanthine-guanine phosphoribosyltransferase mutation assay.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390021.RAb86-Yp96ubBz3hFwZGWZJ6e2xksRzlXnmT2jkgyHa8U130_provenance.
- NP390030.RARb1vjjRBiFxQoBMF0Cct5-jFguJYO53mrPW9ngZweuQ130_assertion description "[The Ingenuity Pathway Analysis of the TNFAIP8 interacting proteins suggested that TNFAIP8 influences cancer progression pathways and networks involving integrins and matrix metalloproteinases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390030.RARb1vjjRBiFxQoBMF0Cct5-jFguJYO53mrPW9ngZweuQ130_provenance.
- NP390031.RAQslvG9tYrUdpUbaRIlD9odRNuzYwUMM_7rFzMwZ8iI0130_assertion description "[Immunohistochemical analysis revealed a correlation between LMP1 and RON expression in biopsies from posttransplantation lymphoproliferative disorder (PTLD), suggesting that LMP1-induced RON expression not only is essential for the growth of LCLs but also may contribute to the pathogenesis of EBV-associated PTLD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390031.RAQslvG9tYrUdpUbaRIlD9odRNuzYwUMM_7rFzMwZ8iI0130_provenance.
- NP390033.RAa_MjG8HA4eCGUx8pxGMS9rR7Lazr2t8rHRV7LPtkYw0130_assertion description "[Complete loss of P/Q calcium channel activity caused by a CACNA1A missense mutation carried by patients with episodic ataxia type 2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390033.RAa_MjG8HA4eCGUx8pxGMS9rR7Lazr2t8rHRV7LPtkYw0130_provenance.
- NP390036.RAYVrxmcbpiE-aseFgSxDA4qihnYD1IFDt_Q5g6TEom-0130_assertion description "[The finding of LOH in ACF with normal expressions of adenomatous polyposis coli (APC) and beta-catenin proteins suggests that LOH can occur very early in colon neoplasia and perhaps even before APC mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390036.RAYVrxmcbpiE-aseFgSxDA4qihnYD1IFDt_Q5g6TEom-0130_provenance.
- NP390037.RAYZeIryfq6UQ303cGHplzuyqZz1m7WgCTfhoSp-_595E130_assertion description "[Four such genes, HPS1, ADTB3A, HPS3, and HPS4, are associated with the four known subtypes of HPS, i.e.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390037.RAYZeIryfq6UQ303cGHplzuyqZz1m7WgCTfhoSp-_595E130_provenance.
- NP390043.RATIzKMGKUdB_f4zg3BZBAEfUg8gboYwmbgZ9V658rWOQ130_assertion description "[The importance of the expression of the autocrine growth system for bombesin-like peptides (BLPS) to the biological behavior of human lung cancer has not been determined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390043.RATIzKMGKUdB_f4zg3BZBAEfUg8gboYwmbgZ9V658rWOQ130_provenance.
- NP390045.RAUSU1ej00leEEbfHTOYKVlDlUX4f_jveUG9JVVmHzk4U130_assertion description "[We examined the insertion (I) and deletion (D) polymorphism in intron 16 of ACE gene by PCR amplification of genomic DNA of 82 patients (37 children), with biopsy-proven IgAN associated with HSP enrolled in a collaborative study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390045.RAUSU1ej00leEEbfHTOYKVlDlUX4f_jveUG9JVVmHzk4U130_provenance.
- NP390046.RARuVFP4K-dxz_aQGRB57TMi_FdNbtMVbYCqA9G-qLhc4130_assertion description "[Among the cognate genes, six including ALG8, DGKE, GNA12, KLF11, LRPAP1, and MMAB are related to multiple genetic diseases such as depressive disorder and Type-II diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390046.RARuVFP4K-dxz_aQGRB57TMi_FdNbtMVbYCqA9G-qLhc4130_provenance.
- NP390048.RAfGOaiAG21J2ItpBluC17KnEdNYWgcaZzFsC2bVKBoeQ130_assertion description "[These findings suggest that a mutation of GAD is not directly involved in all cases of PDS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390048.RAfGOaiAG21J2ItpBluC17KnEdNYWgcaZzFsC2bVKBoeQ130_provenance.
- NP390051.RAXYB_cHGx937quvTZv3_hdZzTj11Cy24AyzX2JXbxk8w130_assertion description "[The natural history of all known patients with French-Canadian Leigh disease (Saguenay-Lac-St-Jean cytochrome c oxidase deficiency, MIM220111, SLSJ-COX), the largest known cohort of patients with a genetically homogeneous, nuclear encoded congenital lactic acidosis, was studied.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390051.RAXYB_cHGx937quvTZv3_hdZzTj11Cy24AyzX2JXbxk8w130_provenance.
- NP390053.RAf9wLRv5c3YGiWxLZx2cUYz6Wl5_-tLyqld6Uui_oWzI130_assertion description "[In HHT1 relatives, 29 of 53 (55%) PAVMs and in HHT2 relatives three of 17 (18%) PAVMS were treated, resulting in a PPV of TTCE for treatable PAVMs of 36.3% and 8.3%, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390053.RAf9wLRv5c3YGiWxLZx2cUYz6Wl5_-tLyqld6Uui_oWzI130_provenance.
- NP390055.RAaXE6CFs0Zm0CFmtnXYrmWYpWqAU6r32XX30pGvU4Dos130_assertion description "[We aimed to determine the frequency of TERC mutations in pediatric patients with aplastic anemia and MDS who required a hematopoietic stem cell transplant.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390055.RAaXE6CFs0Zm0CFmtnXYrmWYpWqAU6r32XX30pGvU4Dos130_provenance.
- NP390059.RAehF6DOBuV0aYXOKsrHga26Ck0w9nJe3tu7Z7wbLB4oM130_assertion description "[Association study between schizophrenia and monoamine oxidase A and B DNA polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390059.RAehF6DOBuV0aYXOKsrHga26Ck0w9nJe3tu7Z7wbLB4oM130_provenance.
- NP390061.RAUFCaoJFmOzMzZTNA9CwEsngoXqg-7-m4KxBRY3R-eAE130_assertion description "[After adjustment for traditional risk factors for atherosclerosis, only the association between severe periodontitis and DBP (odds ratio: 3.1; 95% CI: 1.1 to 8.5; P = 0.03) was confirmed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390061.RAUFCaoJFmOzMzZTNA9CwEsngoXqg-7-m4KxBRY3R-eAE130_provenance.
- NP390064.RAR8UL6Os4NeaHvix_SaVB1Ik81fS2NpE9HTcPkYmhOSA130_assertion description "[To determine the frequency of this mutation in a larger series of patients, we examined 44 index patients with sporadic or familial (seven patients) writer's cramp for the presence of the DYT1 GAG deletion, including eight patients with segmental dystonia involving at least one upper limb.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390064.RAR8UL6Os4NeaHvix_SaVB1Ik81fS2NpE9HTcPkYmhOSA130_provenance.
- NP390068.RAehcGL5Nv2Za8-bW81pxVQab6HnlSIuB1IVTVEdPKgfs130_assertion description "[15dPGJ(2), present within the tumor microenvironment, may act to down-regulate CXCR4 and impact upon the overall process of tumor expansion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390068.RAehcGL5Nv2Za8-bW81pxVQab6HnlSIuB1IVTVEdPKgfs130_provenance.
- NP390071.RAXa0VSqU4LwcjfO_q8sCYnbSEj8T7Ro2xjJRNr87VBPs130_assertion description "[Among 154 known leukaemia-related genes, several oncogenes were found to be upregulated, including LARG, TAL1 and MLL, and of several tumour suppressor genes were downregulated, including DLEU1, RUNX1, FANCD2 and DKC1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390071.RAXa0VSqU4LwcjfO_q8sCYnbSEj8T7Ro2xjJRNr87VBPs130_provenance.
- NP390072.RAciISKO2Zx8dC8Lhf_xXTK3aXLEuBBWokWijx7Kz4ZiQ130_assertion description "[Inflammatory breast cancer specimens had significantly higher mRNA expression levels than noninflammatory breast cancer specimens of the following genes: KDR (P = 0.033), Ang-1, (P = 0.0001), Tie-1 (P = 0.001), Tie-2 (P = 0.001), FGF-2 (P = 0.002), VEGF-C (P = 0.001), VEGF-D (P = 0.012), Flt-4 (P = 0.001), Prox-1 (P = 0.005), and LYVE-1 (P = 0.013).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390072.RAciISKO2Zx8dC8Lhf_xXTK3aXLEuBBWokWijx7Kz4ZiQ130_provenance.
- NP390078.RAXAZ_ZjSG6idNB3TJwbglYJj3d6cui2crdEyY1uPvI_Y130_assertion description "[Sequencing demonstrated INSR haploinsufficiency accounting for elevated insulin levels and dysglycemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390078.RAXAZ_ZjSG6idNB3TJwbglYJj3d6cui2crdEyY1uPvI_Y130_provenance.
- NP390079.RAaJUNcILLi7KZPidgU30wZ30qprVGVTBBGRdfxryf0GE130_assertion description "[In vivo, exposure to low-dose LPS rapidly upregulates B7-1 in podocytes of WT and SCID mice, leading to nephrotic-range proteinuria.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390079.RAaJUNcILLi7KZPidgU30wZ30qprVGVTBBGRdfxryf0GE130_provenance.
- NP390080.RAf50y4j7QzeMzz9g4-m_47A-j27pBzbI4BzCK4SC4BgE130_assertion description "[Nephrotic syndrome (NS) in infancy includes NS of Finnish type (mutation of the nephrin gene), diffuse mesangial sclerosis (idiopathic or linked to WT1 mutation), idiopathic NS, most often steroid resistant, and NS related to infections during pregnancy (virus, syphilis, toxoplasmosis).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390080.RAf50y4j7QzeMzz9g4-m_47A-j27pBzbI4BzCK4SC4BgE130_provenance.
- NP390083.RAXHS9ipCdO7_7jQtnA5k9cdAuZ6NaK7ikUH2Hqmerqjs130_assertion description "[This study assessed the clinical and laboratory factors involved in BMD of 45 patients at the Pediatric Unit of Endocrinology, UNICAMP, who had been diagnosed as having classical CAH due to CYP21A2 deficiency including molecular characterization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390083.RAXHS9ipCdO7_7jQtnA5k9cdAuZ6NaK7ikUH2Hqmerqjs130_provenance.
- NP390084.RAYhL6UuxIaRd5KIX5RD2U8SSfLmKE6e5OwEkMWx9pcUA130_assertion description "[We report here the identification of five novel ARHGEF5/TIM alternative transcripts specifically expressed in breast tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390084.RAYhL6UuxIaRd5KIX5RD2U8SSfLmKE6e5OwEkMWx9pcUA130_provenance.
- NP390092.RAXG6RYjNnZ_Mcai-m87NvN0KF0QVlrLy07xZCIkEmp78130_assertion description "[Using phosphomimetic and non-phosphorylatable ezrin mutants, we show that the S1P-induced cytoskeletal protrusions are dependent on ERM phosphorylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390092.RAXG6RYjNnZ_Mcai-m87NvN0KF0QVlrLy07xZCIkEmp78130_provenance.
- NP390097.RAcaU6CNW0oBXS4cFx7Tvf-_8IGKGFFiNdIbYj3ddxT1E130_assertion description "[These include complex diseases like Alzheimer's disease and Parkinson's disease, and Mendelian diseases caused by polyglutamine expansion mutations [like Huntington's disease (HD) and various spinocerebellar ataxias (SCAs), like SCA3].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390097.RAcaU6CNW0oBXS4cFx7Tvf-_8IGKGFFiNdIbYj3ddxT1E130_provenance.
- NP390098.RAWuTT8X4gnbS9ZW4iOdkbsYuEwrAbeGAqGCcZY84gbzk130_assertion description "[Cyclin D1 and D3 associate with the SCF complex and are coordinately elevated in breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390098.RAWuTT8X4gnbS9ZW4iOdkbsYuEwrAbeGAqGCcZY84gbzk130_provenance.
- NP390100.RAT2p2a7ILZzy8pvjU2GRdwoGMVwe5kgiX96GqLKnknio130_assertion description "[In the last few years, several studies have shown a correlation between ras activation and alterations in the expression of cyclin D1 as well as other cell cycle-regulated proteins, but the actual role of these alterations in tumor development had not been determined until a recent study provided genetic and biochemical evidence that cyclin D1 is a critical target of oncogenic ras in mouse skin carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390100.RAT2p2a7ILZzy8pvjU2GRdwoGMVwe5kgiX96GqLKnknio130_provenance.
- NP390102.RAaXoexu_VH7mNmZU_4t_TKgCEzGZO5Mgw1liECVVyT_M130_assertion description "[Of the inherited thrombophilias, factor V Leiden and the prothrombin 20210 mutation have been associated with stroke, but this association is statistically significant only in children and adults under age 40.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390102.RAaXoexu_VH7mNmZU_4t_TKgCEzGZO5Mgw1liECVVyT_M130_provenance.
- NP390110.RAVvUzwdQ8vIE1u43lZN1NEXT9LHWOzAKZhcMaodbioNM130_assertion description "[Linkage to 1p35-p36 (CMT2A), 3q (CMT2B), and 7p (CMT2D) chromosomes has been reported in the disease; however, most HMSN II families do not link to any of the reported loci.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390110.RAVvUzwdQ8vIE1u43lZN1NEXT9LHWOzAKZhcMaodbioNM130_provenance.
- NP390116.RAX0aEneWeVP1oudTRVn2BwevMfoKQZownficVCNl8jSg130_assertion description "[The MVD was significantly correlated with VEGF165, VEGF189, Ang2 and EG-VEGF mRNA with Spearman's related coefficient being 0.764, 0.510, 0.640 and 0.366 in HCC (P = 0.000, 0.000 0.000 and 0.003).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390116.RAX0aEneWeVP1oudTRVn2BwevMfoKQZownficVCNl8jSg130_provenance.
- NP390117.RAevYZ63g1bZSqPtQucQyaBypQfNrKRuhZCncubGGol1I130_assertion description "[Experimental evidence indicates that (1) Ca2+ homeostasis is abnormal in mitochondria isolated from lymphoblasts of HD patients and from brains of the YAC72 HD mouse model; (2) Httexp leads to potentiation of NR1/NR2B NMDA receptor activity in heterologous expression systems and in MSN from YAC72 HD mouse model; and (3) Httexp binds to the type 1 inositol 1,4,5-trisphosphate receptor (InsP3R1) carboxy-terminus and causes sensitization of InsP3R1 to activation by InsP3 in planar lipid bilayers and in MSN.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390117.RAevYZ63g1bZSqPtQucQyaBypQfNrKRuhZCncubGGol1I130_provenance.
- NP390118.RAZnXo5mDKdhSkuIlELNIBNoeeC34Z2IWLJdndQvZo4fY130_assertion description "[In the present study, we describe the expression of caveolin-1 (cav-1) in 64 brain tumors of different grade, of either astroglial or oligodendroglial origin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390118.RAZnXo5mDKdhSkuIlELNIBNoeeC34Z2IWLJdndQvZo4fY130_provenance.
- NP390126.RAUkmIYOjOoiQ9gca9IsnSWKfBDRddSlfMjKd8-VWH6xI130_assertion description "[In situ hybridization and immunocytochemistry were used to determine the number of cells expressing IL-18, IFN-gamma, IL-5 and major basic protein (MBP) within lung tissue from Balb/c mice stimulated with LPS, OVA and in normal control mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390126.RAUkmIYOjOoiQ9gca9IsnSWKfBDRddSlfMjKd8-VWH6xI130_provenance.
- NP390129.RAZNi_GYy3FvoDyiEb8Qei-t_sIbYKp_Sz21Gve0l0I7w130_assertion description "[Diabetic nephropathy (defined as urinary albumin excretion greater than 300 mg/24 hr) was found in 7 out of 21 siblings to patients with nephropathy and 3 out of 30 siblings to normoalbuminuric patients (P less than 0.04).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390129.RAZNi_GYy3FvoDyiEb8Qei-t_sIbYKp_Sz21Gve0l0I7w130_provenance.
- NP390141.RAee0hh9xoewUTHuAcPd4E9OltWw2dpkUtWNeUP7RMi9Y130_assertion description "[Through GWAS, we identified a novel SNP associated with RA at the APOM gene in the MHC class III region on 6p21.33 (rs805297, odds ratio (OR) = 2.28, P = 5.20 × 10-7).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390141.RAee0hh9xoewUTHuAcPd4E9OltWw2dpkUtWNeUP7RMi9Y130_provenance.
- NP390142.RAYw4LHKQBRQ00mXbBHcQExeDNRGWa-M_vhoSWYGn_O_Q130_assertion description "[Microsatellite mutations of transforming growth factor-beta receptor type II and caspase-5 occur in human precursor T-cell lymphoblastic lymphomas/leukemias in vivo but are not associated with hMSH2 or hMLH1 promoter methylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390142.RAYw4LHKQBRQ00mXbBHcQExeDNRGWa-M_vhoSWYGn_O_Q130_provenance.
- NP390145.RAXnVu71cYYYLDshXW36-DOPUcTcAVNw_b2W68V4B-UJs130_assertion description "[Given the accumulating evidence that Survivin, a new member of the inhibitor of apoptosis (IAP) family, is associated with both cancer progression and drug resistance, we hypothesized that Survivin plays a potentially important role in hormone therapy resistance, and that targeting of Survivin may enhance sensitivity to antiandrogen therapy in prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390145.RAXnVu71cYYYLDshXW36-DOPUcTcAVNw_b2W68V4B-UJs130_provenance.
- NP390151.RAVi_nwnbSgtqBjEzSDzbUMFz8LHkqapdo7q0PIVwopK8130_assertion description "[A Cirrhosis Risk Score (CRS) based on seven genetic variants has been recently developed for identifying patients at risk for cirrhosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390151.RAVi_nwnbSgtqBjEzSDzbUMFz8LHkqapdo7q0PIVwopK8130_provenance.
- NP390152.RAV2OB50aBAu-jeU_xAP-oMKbzs56VeXY20mTWSfq42Kk130_assertion description "[Overexpression of FGF-2 mRNA is associated with tumor recurrence and reduced survival after surgical resection of esophageal cancer and that these risks are reduced in tumors coexpressing the FGF-AS mRNA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP390152.RAV2OB50aBAu-jeU_xAP-oMKbzs56VeXY20mTWSfq42Kk130_provenance.